pdb
stringlengths
4
4
Hchain
stringclasses
59 values
Lchain
stringclasses
60 values
model
int64
0
76
antigen_chain
stringclasses
386 values
antigen_type
stringclasses
24 values
antigen_het_name
stringclasses
240 values
antigen_name
stringlengths
1
396
short_header
stringclasses
448 values
date
stringlengths
8
8
compound
stringlengths
4
243
organism
stringlengths
3
175
heavy_species
stringclasses
121 values
light_species
stringclasses
67 values
antigen_species
stringclasses
937 values
authors
stringlengths
6
762
resolution
stringlengths
1
8
method
stringclasses
10 values
r_free
stringclasses
354 values
r_factor
stringclasses
342 values
scfv
bool
2 classes
engineered
bool
2 classes
heavy_subclass
stringclasses
14 values
light_subclass
stringclasses
35 values
light_ctype
stringclasses
3 values
affinity
float64
0
0
delta_g
float64
-16.91
-5.04
affinity_method
stringclasses
11 values
temperature
float64
4
37
pmid
stringclasses
157 values
6vrq
A
B
0
null
null
null
null
IMMUNE SYSTEM
02/08/20
Crystal structure of gl12A21 Fab in complex with anti-idiotypic iv12 Fab
MUS MUSCULUS; HOMO SAPIENS
homo sapiens
homo sapiens
null
Aljedani, S.S., Weidle, C., Pancera, M.
2.57
X-RAY DIFFRACTION
0.241
0.189
false
true
IGHV1
IGKV1
Kappa
null
null
null
null
null
1zmy
A
null
0
L
protein
null
lysozyme c
IMMUNE SYSTEM/HYDROLASE
05/11/05
cAbBCII-10 VHH framework with CDR loops of cAbLys3 grafted on it and in complex with hen egg white lysozyme
CAMELUS DROMEDARIUS; GALLUS GALLUS
camelus dromedarius
null
gallus gallus
Saerens, D., Pellis, M., Loris, R., Pardon, E., Dumoulin, M., Matagne, A., Wyns, L., Muyldermans, S., Conrath, K.
3.0
X-RAY DIFFRACTION
0.254
0.206
false
true
IGHV1
null
null
0
-9.93
SPR
null
16095608
5tsj
1
null
0
J | H
protein | protein
NA | NA
v-type atpase subunit g | v-type atp synthase subunit e
membrane protein, hydrolase
10/29/16
Thermus thermophilus V/A-ATPase bound to VH dAbs
HOMO SAPIENS; THERMUS THERMOPHILUS (STRAIN HB8 / ATCC 27634 / DSM 579)
homo sapiens
null
thermus thermophilus (strain hb8 / atcc 27634 /dsm 579) | thermus thermophilus (strain hb8 / atcc 27634 /dsm 579)
Davies, R.B., Smits, C., Wong, A.S.W., Stock, D., Sandin, S., Stewart, A.G.
8.7
ELECTRON MICROSCOPY
null
null
false
true
IGHV3
null
null
null
null
null
null
null
7rm0
E
F
0
R
peptide
null
peptide from circumsporozoite protein variant vk247
ANTIMICROBIAL PROTEIN
07/26/21
Antibody 2E10.E9 in complex with P. vivax CSP peptide ANGAGNQPGANGAGNQPG
MUS MUSCULUS; SYNTHETIC CONSTRUCT
mus musculus
mus musculus
plasmodium vivax
Kucharska, I., Ivanochko, D., Julien, J.P.
2.71
X-RAY DIFFRACTION
0.246
0.209
false
true
IGHV9
IGKV8
Kappa
null
null
null
null
null
2fr4
H
L
0
N
nucleic-acid
null
5'-d(*cp*tp*gp*cp*cp*tp*tp*cp*ap*g)-3'
IMMUNE SYSTEM/DNA
01/18/06
Structure of Fab DNA-1 complexed with a stem-loop DNA ligand
MUS MUSCULUS; SYNTHETIC CONSTRUCT
mus musculus
mus musculus
null
Tanner, J.J., Ou, Z.
1.95
X-RAY DIFFRACTION
0.256
0.207
false
true
IGHV1
IGKV12
Kappa
0.000004
-7.364108
Unknown
null
TBD
7cvy
D
E
0
B
protein
null
e2 glycoprotein
IMMUNE SYSTEM/VIRUS
08/27/20
Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-124
MUS MUSCULUS; CHIKUNGUNYA VIRUS
mus musculus
mus musculus
chikungunya virus
Zhou, Q.F., Fox, J.M., Earnest, J.T., Ng, T.S., Kim, A.S., Fibriansah, G., Kostyuchenko, V.A., Shu, B., Diamond, M.S., Lok, S.M.
5.2
ELECTRON MICROSCOPY
null
null
false
false
IGHV6
IGKV6
Kappa
null
null
null
null
null
4y5x
A
B
0
C
protein
null
erythropoietin receptor
protein binding/immune system
02/12/15
Diabody 305 complex with EpoR
HOMO SAPIENS
homo sapiens
homo sapiens
homo sapiens
Moraga, I., Guo, F., Ozkan, E., Jude, K.M., Garcia, K.C.
3.15
X-RAY DIFFRACTION
0.241
0.201
false
true
IGHV3
IGLV1
Lambda
null
null
null
null
null
7zmv
E
null
0
D
protein
null
atp-dependent dna helicase q5
HYDROLASE
04/19/22
Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G5-006
Homo sapiens; Lama glama
lama glama
null
homo sapiens
Ye, M., Makola, M., Newman, J.A., Fairhead, M., MacLean, E., Krojer, T., Aitkenhead, H., Bountra, C., Gileadi, O., von Delft, F.
2.002
X-RAY DIFFRACTION
0.275
0.242
false
true
IGHV1
null
null
null
null
null
null
null
3lrs
E
F
0
F
carbohydrate
NAG
N-ACETYL-D-GLUCOSAMINE
IMMUNE SYSTEM
02/11/10
Structure of PG16, an antibody with broad and potent neutralization of HIV-1
HOMO SAPIENS
homo sapiens
homo sapiens
homo sapiens
Pancera, M., Kwong, P.D.
2.37
X-RAY DIFFRACTION
0.260
0.211
false
true
IGHV3
IGLV2
Lambda
null
null
null
null
null
6uye
H
K
0
B
protein
null
sgp
VIRAL PROTEIN/IMMUNE SYSTEM
11/13/19
EBOV GPdMuc Makona bound to rEBOV-548 Fab
EBOLA VIRUS; HOMO SAPIENS
homo sapiens
homo sapiens
ebola virus
Murin, C.D., Ward, A.B.
3.96
ELECTRON MICROSCOPY
null
null
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
5f6h
O
P
0
null
null
null
null
IMMUNE SYSTEM
12/06/15
Crystal Structure of Tier 2 Neutralizing Antibody DH427 from a Rhesus Macaque
HOMO SAPIENS
homo sapiens
homo sapiens
null
Fera, D., Harrison, S.C.
2.66
X-RAY DIFFRACTION
0.262
0.230
false
true
IGHV3
IGLV2
Lambda
null
null
null
null
null
4ttd
H
L
0
A
protein
null
lysozyme c
IMMUNE SYSTEM
06/20/14
Structure of a lysozyme antibody complex
HOMO SAPIENS; GALLUS GALLUS
homo sapiens
homo sapiens
gallus gallus
Wensley, B.
2.15
X-RAY DIFFRACTION
0.279
0.255
false
true
IGHV3
IGLV1
Lambda
null
null
null
null
null
7mmn
M
G
0
K
protein
null
fusion glycoprotein f1,fibritin
IMMUNE SYSTEM/VIRAL PROTEIN
04/29/21
Crystal Structure of the Prefusion RSV F Glycoprotein bound by human antibody AM14
HOMO SAPIENS; HUMAN RESPIRATORY SYNCYTIAL VIRUS; ENTEROBACTERIA PHAGE T4
homo sapiens
homo sapiens
human respiratory syncytial virus,enterobacteria phage t4
Harshbarger, W., Malito, E.
3.57
X-RAY DIFFRACTION
0.245
0.202
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
5dd6
A
B
0
null
null
null
null
IMMUNE SYSTEM
08/24/15
Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
MACACA MULATTA
macaca mulatta
macaca mulatta
null
Nicely, N.I., Pemble IV, C.W., Haynes, B.F.
1.699
X-RAY DIFFRACTION
0.224
0.191
false
true
IGHV4
IGKV1
Kappa
null
null
null
null
null
6z06
H
L
0
A
protein
null
envelope polyprotein
VIRAL PROTEIN
05/07/20
Crystal structure of Puumala virus Gc in complex with Fab 4G2
MYODES GLAREOLUS; PUUMALA ORTHOHANTAVIRUS
myodes glareolus
myodes glareolus
puumala orthohantavirus
Rissanen, I.R., Stass, R., Krumm, S.A., Seow, J., Hulswit, R.J.G., Paesen, G.C., Hepojoki, J., Vapalahti, O., Lundkvist, A., Reynard, O., Volchkov, V., Doores, K.J., Huiskonen, J.T., Bowden, T.A.
3.5
X-RAY DIFFRACTION
0.264
0.217
false
true
IGHV5
unknown
unknown
null
null
null
null
null
3pnw
N
M
0
O
protein
null
tudor domain-containing protein 3
PROTEIN BINDING/IMMUNE SYSTEM
11/19/10
Crystal Structure of the tudor domain of human TDRD3 in complex with an anti-TDRD3 FAB
HOMO SAPIENS, SYNTHETIC CONSTRUCT; HOMO SAPIENS
synthetic
synthetic
homo sapiens
Loppnau, P., Tempel, W., Wernimont, A.K., Lam, R., Ravichandran, M., Adams-Cioaba, M.A., Persson, H., Sidhu, S.S., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Cossar, D., Structural Genomics Consortium (SGC)
2.05
X-RAY DIFFRACTION
0.264
0.223
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
6vbg
C
null
0
A
protein
null
galactoside permease
PROTEIN TRANSPORT
12/18/19
Lactose permease complex with thiodigalactoside and nanobody 9043
ESCHERICHIA COLI; LAMA GLAMA
lama glama
null
escherichia coli
Kumar, H., Stroud, R.M., Kaback, H.R., Finer-Moore, J., Smirnova, I., Kasho, V., Pardon, E., Steyart, J.
2.8
X-RAY DIFFRACTION
0.275
0.239
false
true
IGHV1
null
null
null
null
null
null
null
7lu9
m
n
0
I
carbohydrate
MAN
ALPHA-D-MANNOSE
VIRAL PROTEIN/IMMUNE SYSTEM
02/21/21
Cryo-EM structure of DH851.3 bound to HIV-1 CH505 Env
MACACA MULATTA; HUMAN IMMUNODEFICIENCY VIRUS 1
macaca mulatta
macaca mulatta
null
Manne, K., Edwards, R.J., Acharya, P.
5.6
ELECTRON MICROSCOPY
null
null
false
false
IGHV2
IGLV2
Lambda
null
null
null
null
null
7s13
I
M
0
C
protein
null
t-cell surface protein tactile
IMMUNE SYSTEM
08/31/21
Crystal structure of Fab in complex with mouse CD96 dimer
RATTUS; MUS MUSCULUS
rattus
rattus
mus musculus
Lee, P.S., Barman, I., Strop, P.
2.12
X-RAY DIFFRACTION
0.265
0.217
false
true
IGHV2
IGLV3
Lambda
null
null
null
null
null
6bzw
A
B
0
J
peptide
null
e2 as412 peptide
IMMUNE SYSTEM
12/26/17
Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the GL precursor of the broadly neutralizing antibody AP33
MUS MUSCULUS; SYNTHETIC CONSTRUCT
mus musculus
mus musculus
hepatitis c virus
Tzarum, N., Alemn, F., Wilson, I.A., Law, M.
2.2
X-RAY DIFFRACTION
0.231
0.192
false
true
IGHV3
IGKV3
Kappa
null
null
null
null
null
7lrt
F
G
0
B
protein
null
sars-cov-2 spike glycoprotein
VIRAL PROTEIN/IMMUNE SYSTEM
02/17/21
Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody A23-58.1 that targets the receptor-binding domain
HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2
homo sapiens
homo sapiens
severe acute respiratory syndrome coronavirus2
Zhou, T., Tsybovsky, T.
3.54
ELECTRON MICROSCOPY
null
null
false
true
IGHV1
IGKV3
Kappa
null
null
null
null
null
3oko
B
A
0
B
carbohydrate
KDA
polysaccharide
IMMUNE SYSTEM
08/25/10
Crystal structure of S25-39 in complex with Kdo(2.8)Kdo(2.4)Kdo
MUS MUSCULUS
mus musculus
mus musculus
mus musculus
Blackler, R.J., Evans, S.V.
2.45
X-RAY DIFFRACTION
0.267
0.210
false
false
IGHV7
IGKV8
Kappa
null
null
null
null
null
6eyo
H
L
0
A
protein
null
immunoglobulin heavy constant epsilon
IMMUNE SYSTEM
11/13/17
Structure of extended IgE-Fc in complex with two anti-IgE Fabs
HOMO SAPIENS
homo sapiens
homo sapiens
homo sapiens
Chen, J.B., Ramadani, F., Pang, M.O.Y., Beavil, R.L., Holdom, M.D., Mitropoulou, A.N., Beavil, A.J., Gould, H.J., Chang, T.W., Sutton, B.J., McDonnell, J.M., Davies, A.M.
3.7
X-RAY DIFFRACTION
0.288
0.247
false
true
IGHV1
IGKV3
Kappa
0
-14.596007
SPR
null
TBD
1mf2
H
L
0
null
null
null
null
IMMUNOGLOBULIN
12/27/96
ANTI HIV1 PROTEASE FAB COMPLEX
MUS MUSCULUS
mus musculus
mus musculus
null
Lescar, J., Bentley, G.A.
2.6
X-RAY DIFFRACTION
0.307
0.206
false
false
IGHV5
IGKV3
Kappa
null
null
null
null
null
7sg5
H
L
0
A
peptide
null
pfcsp peptide 21
IMMUNE SYSTEM
10/05/21
Structure of PfCSP peptide 21 with antibody CIS43_Var2
Homo sapiens; SYNTHETIC CONSTRUCT
homo sapiens
homo sapiens
synthetic construct
Tripathi, P., Kwong, P.D.
1.4
X-RAY DIFFRACTION
0.218
0.185
false
true
IGHV1
IGKV4
Kappa
null
null
null
null
null
5mv4
L
M
0
N
peptide
null
synthetic peptide containing the citrullinated collagentype ii epitope cii616-639,collagen alpha-1(ii) chain,synthetic peptide containing the citrullinated collagen type ii epitope cii616- 639
IMMUNE SYSTEM
01/15/17
ACC1 Fab fragment in complex with citrullinated CII616-639 epitope of collagen type II (ptm23)
MUS MUSCULUS; SYNTHETIC CONSTRUCT
mus musculus
mus musculus
mus musculus
Dobritzsch, D., Holmdahl, R., Ge, C.
2.9
X-RAY DIFFRACTION
0.247
0.232
false
false
IGHV6
IGKV3
Kappa
null
null
null
null
null
7o30
B
A
0
Q
peptide
null
pas#1 epitope peptide
IMMUNE SYSTEM
04/01/21
Crystal structure of the anti-PAS Fab 1.1 in complex with its epitope peptide
MUS MUSCULUS; SYNTHETIC CONSTRUCT
mus musculus
mus musculus
synthetic construct
Schilz, J., Schiefner, A., Skerra, A.
2.65
X-RAY DIFFRACTION
0.269
0.220
false
true
IGHV2
IGKV3
Kappa
null
null
null
null
null
1rjc
A
null
0
B
protein
null
lysozyme c
IMMUNE SYSTEM/HYDROLASE
11/19/03
Crystal structure of the camelid single domain antibody cAb-Lys2 in complex with hen egg white lysozyme
CAMELUS DROMEDARIUS; GALLUS GALLUS
camelus dromedarius
null
gallus gallus
De Genst, E., Silence, K., Ghahroudi, M.A., Decanniere, K., Loris, R., Kinne, J., Wyns, L., Muyldermans, S.
1.4
X-RAY DIFFRACTION
0.235
0.220
false
true
IGHV1
null
null
null
null
null
null
null
3ifp
H
L
0
P
peptide
null
amyloid beta a4 protein
IMMUNE SYSTEM
07/24/09
X-ray structure of amyloid beta peptide:antibody (Abeta1-7:12B4) complex
MUS MUSCULUS; SYNTHETIC CONSTRUCT
mus musculus
mus musculus
homo sapiens
Weis, W.I., Feinberg, H., Basi, G.S., Schenk, D.
2.95
X-RAY DIFFRACTION
0.269
0.235
false
true
IGHV8
IGKV1
Kappa
0
-10.38
SPR
25
19923222
6w4m
H
L
0
G | N
protein | peptide
NA | NA
clade a/e 93th057 hiv-1 gp120 core | m48u1 cd4 mimetic peptide
VIRAL PROTEIN/IMMUNE SYSTEM
03/11/20
CRYSTAL STRUCTURE OF THE ADCC-POTENT, WEAKLY NEUTRALIZING HIV ENV CO-RECEPTOR BINDING SITE ANTIBODY N12-I2 FAB IN COMPLEX WITH HIV-1 CLADE A/E GP120 AND M48U1
HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS; SYNTHETIC CONSTRUCT
homo sapiens
homo sapiens
human immunodeficiency virus 1 | synthetic construct
Tolbert, W.D., Gohain, N., Pazgier, M.
3.2
X-RAY DIFFRACTION
0.301
0.241
false
true
IGHV1
IGKV3
Kappa
null
null
null
null
null
2f5b
H
L
0
P
peptide
null
protein (gp41 epitope)
IMMUNOGLOBULIN
04/09/99
CRYSTAL STRUCTURE OF FAB' FROM THE HIV-1 NEUTRALIZING ANTIBODY 2F5 IN COMPLEX WITH ITS GP41 EPITOPE
HOMO SAPIENS; SYNTHETIC CONSTRUCT
homo sapiens
homo sapiens
null
Bryson, S., Julien, J.P., Hynes, R.C., Pai, E.F.
2.0
X-RAY DIFFRACTION
0.258
0.232
false
false
IGHV2
IGKV1
Kappa
null
null
null
null
null
7mlv
F
null
0
D
protein
null
glycine receptor alpha 1
MEMBRANE PROTEIN, SIGNALING PROTEIN
04/29/21
Cryo-EM reveals partially and fully assembled native glycine receptors,homomeric tetramer
RATTUS NORVEGICUS; SUS SCROFA
rattus norvegicus
null
sus scrofa
Zhu, H., Gouaux, E.
4.1
ELECTRON MICROSCOPY
null
null
false
true
IGHV1
null
null
null
null
null
null
null
2hfg
H
L
0
R
peptide
null
tumor necrosis factor receptor superfamily member 13c
IMMUNE SYSTEM
06/23/06
Crystal structure of hBR3 bound to CB3s-Fab
HOMO SAPIENS
homo sapiens
homo sapiens
homo sapiens
Hymowitz, S.G.
2.61
X-RAY DIFFRACTION
0.252
0.195
false
true
IGHV3
IGKV1
Kappa
0
-12.57
SPR
25
16840730
5u3o
H
L
0
A
peptide
null
gp41 mper peptide
IMMUNE SYSTEM/VIRAL PROTEIN
12/02/16
Crystal Structure of DH511.2_K3 Fab in Complex with HIV-1 gp41 MPER Peptide
HOMO SAPIENS; SYNTHETIC CONSTRUCT
homo sapiens
homo sapiens
human immunodeficiency virus 1
Ofek, G., Wu, L., Lougheed, C.S., Williams, L.D., Nicely, N.I., Haynes, B.F.
1.761
X-RAY DIFFRACTION
0.192
0.161
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
7swd
H
h
0
D | E
protein | protein
NA | NA
virion spike glycoprotein | small/secreted glycoprotein
VIRAL PROTEIN/Immune System
11/19/21
Structure of EBOV GP lacking the mucin-like domain with 1C11 scFv and 1C3 Fab bound
ZAIRE EBOLAVIRUS (STRAIN GABON-94); ZAIRE EBOLAVIRUS; HOMO SAPIENS
homo sapiens
null
zaire ebolavirus | zaire ebolavirus (strain gabon-94)
Milligan, J.C., Yu, X., Saphire, E.O.
3.59
ELECTRON MICROSCOPY
null
null
true
true
unknown
unknown
unknown
null
null
null
null
null
1mci
null
B
0
P
peptide
null
peptide n-acetyl-d-phe-l-his-d-pro-oh
IMMUNE SYSTEM
02/25/93
PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS
HOMO SAPIENS
null
homo sapiens
null
Edmundson, A.B., Harris, D.L., Fan, Z.-C., Guddat, L.W.
2.7
X-RAY DIFFRACTION
unknown
0.177
false
true
null
IGLV2
Lambda
null
null
null
null
null
4x7e
C
null
0
A
protein
null
capsid protein
VIRAL PROTEIN
12/09/14
Crystal structure of norovirus GII.10 P domain in complex with Nano-85
NORWALK VIRUS; VICUGNA PACOS
vicugna pacos
null
norwalk virus
Hansman, G.H., Koromyslova, A.D.
2.11
X-RAY DIFFRACTION
0.218
0.189
false
true
IGHV1
null
null
0
-11.125277
ITC
null
TBD
5jmr
B
null
0
null
null
null
null
IMMUNE SYSTEM
04/29/16
X-ray structure of an camelid VHH fragment
CAMELUS DROMEDARIUS
camelus dromedarius
null
null
Dahms, S.O., Than, M.E.
2.27
X-RAY DIFFRACTION
0.216
0.190
false
true
IGHV3
null
null
null
null
null
null
null
7zmp
C
null
0
A
protein
null
atp-dependent dna helicase q5
HYDROLASE
04/19/22
Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G3-055
Homo sapiens; Lama glama
lama glama
null
homo sapiens
Ye, M., Makola, M., Newman, J.A., Fairhead, M., MacLean, E., Krojer, T., Aitkenhead, H., Bountra, C., Gileadi, O., von Delft, F.
3.626
X-RAY DIFFRACTION
0.359
0.332
false
true
IGHV1
null
null
null
null
null
null
null
6q0i
H
L
0
A
protein
null
hemagglutinin
IMMUNE SYSTEM
08/01/19
Inferred intermediate I-7 (I-7-6) of the human antibody lineage 652 in complex with influenza hemagglutinin head domain of A/Beijing/262/95(H1N1)
INFLUENZA A VIRUS (A/BEIJING/262/1995(H1N1)); HOMO SAPIENS
homo sapiens
homo sapiens
influenza a virus (a/beijing/262/1995(h1n1))
McCarthy, K.R., Harrison, S.C.
2.702
X-RAY DIFFRACTION
0.255
0.213
false
true
IGHV4
IGLV3
Lambda
null
null
null
null
null
3qa3
D
C
0
G
protein
null
integrin alpha-m
IMMUNE SYSTEM/ cell adhesion
01/10/11
Crystal Structure of A-domain in complex with antibody
HOMO SAPIENS; MUS MUSCULUS
mus musculus
mus musculus
homo sapiens
Mahalingam, B., Xiong, J.P., Arnaout, M.A.
3.0
X-RAY DIFFRACTION
0.224
0.194
false
false
IGHV14
IGKV8
Kappa
null
null
null
null
null
5n0a
I
M
0
B
protein
null
envelope glycoprotein e
Immune System/Viral protein
02/02/17
Crystal structure of A259C covalently linked dengue 2 virus envelope glycoprotein dimer in complex with the Fab fragment of the broadly neutralizing human antibody EDE2 A11
HOMO SAPIENS; DENGUE VIRUS 2
homo sapiens
homo sapiens
dengue virus 2
Vaney, M.C., Rouvinski, A., Guardado-Calvo, P., Sharma, A., Rey, F.A.
3.9
X-RAY DIFFRACTION
0.300
0.285
false
true
IGHV3
IGLV2
Lambda
null
null
null
null
null
6tnp
B
A
0
H
unknown
NO8
unknown
IMMUNE SYSTEM
12/09/19
Crystal structure of the ScFv-5E5 in complex with a Tn glycopeptide
MUS MUSCULUS
mus musculus
mus musculus
mus musculus
Macias-Leon, J., Corzana, F., Hurtado-Guerrero, R.
3.0
X-RAY DIFFRACTION
0.251
0.203
false
true
IGHV1
IGKV8
Kappa
null
null
null
null
null
3k1k
D
null
0
B
protein
null
green fluorescent protein
LUMINESCENT PROTEIN/IMMUNE SYSTEM
09/28/09
Green fluorescent protein bound to minimizer nanobody
AEQUOREA VICTORIA; CAMELUS DROMEDARIUS
lama pacos
null
aequorea victoria
Kirchhofer, A., Helma, J., Schmidthals, K., Frauer, C., Cui, S., Karcher, A., Pellis, M., Muyldermans, S., Delucci, C.C., Cardoso, M.C., Leonhardt, H., Hopfner, K.-P., Rothbauer, U.
2.15
X-RAY DIFFRACTION
0.255
0.212
false
true
IGHV1
null
null
null
null
null
null
null
1i7z
B
A
0
A
Hapten
COC
COCAINE
IMMUNE SYSTEM
03/12/01
ANTIBODY GNC92H2 BOUND TO LIGAND
MUS MUSCULUS, HOMO SAPIENS
mus musculus, homo sapiens
mus musculus, homo sapiens
mus musculus, homo sapiens
Larsen, N.A., Wilson, I.A.
2.3
X-RAY DIFFRACTION
0.265
0.220
false
true
IGHV9
IGKV3
Kappa
0
-8.728352
Unknown
null
TBD
7zf9
A
B
0
C
protein
null
spike protein s1
VIRAL PROTEIN
04/01/22
SARS-CoV-2 Omicron BA.2 RBD in complex with COVOX-150 Fab (P21)
HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2
homo sapiens
homo sapiens
severe acute respiratory syndrome coronavirus2
Zhou, D., Huo, J., Ren, J., Stuart, D.I.
3.25
X-RAY DIFFRACTION
0.265
0.222
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
5veb
H
L
0
Y
protein
null
cadherin-6
IMMUNE SYSTEM
04/04/17
Crystal structure of a Fab binding to extracellular domain 5 of Cadherin-6
HOMO SAPIENS
homo sapiens
homo sapiens
homo sapiens
Zhu, X., Bialucha, C.U., London, A., Clark, K., Hu, T.
2.34
X-RAY DIFFRACTION
0.252
0.212
false
false
IGHV3
IGKV1
Kappa
null
null
null
null
null
7p60
H
null
0
D
protein
null
volume-regulated anion channel subunit lrrc8a
MEMBRANE PROTEIN
07/15/21
Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb4 at 1:0.5 ratio
MUS MUSCULUS; SYNTHETIC CONSTRUCT
synthetic construct
null
mus musculus
Deneka, D., Rutz, S., Sawicka, M.
3.8
ELECTRON MICROSCOPY
null
null
false
true
IGHV1
null
null
null
null
null
null
null
7e3k
F
G
0
B
protein
null
spike glycoprotein
VIRAL PROTEIN
02/09/21
Ultrapotent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants
SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS
homo sapiens
homo sapiens
severe acute respiratory syndrome coronavirus2
Guo, H., Li, T., Liu, F., Gao, Y., Ji, X., Yang, H.
3.9
ELECTRON MICROSCOPY
null
null
false
true
IGHV1
IGKV3
Kappa
null
null
null
null
null
1mcw
null
M
0
null
null
null
null
IMMUNOGLOBULIN
05/09/89
THREE-DIMENSIONAL STRUCTURE OF A HYBRID LIGHT CHAIN DIMER. PROTEIN ENGINEERING OF A BINDING CAVITY
HOMO SAPIENS
null
homo sapiens
null
Ely, K.R., Herron, J.N., Edmundson, A.B.
3.5
X-RAY DIFFRACTION
unknown
unknown
false
false
null
IGLV2
Lambda
null
null
null
null
null
5f93
D
null
0
B
protein
null
adhesin binding fucosylated histo-blood group antigen,adhesin,adhesin binding fucosylated histo-blood group antigen
CELL ADHESION
12/09/15
Blood group antigen binding adhesin BabA of Helicobacter pylori strain A730 in complex with blood group H Lewis b hexasaccharide
HELICOBACTER PYLORI; LAMA GLAMA
lama glama
null
helicobacter pylori
Moonens, K., Gideonsson, P., Subedi, S., Romao, E., Oscarson, S., Muyldermans, S., Boren, T., Remaut, H.
2.99
X-RAY DIFFRACTION
0.234
0.181
false
true
IGHV1
null
null
null
null
null
null
null
6cse
A
B
0
C
protein
null
sodium/alanine symporter agcs
MEMBRANE PROTEIN
03/20/18
Crystal structure of sodium/alanine symporter AgcS with L-alanine bound
METHANOCOCCUS MARIPALUDIS (STRAIN S2 / LL); MUS MUSCULUS
mus musculus
mus musculus
methanococcus maripaludis (strain s2 / ll)
Ma, J., Reyes, F.E., Gonen, T.
3.24
X-RAY DIFFRACTION
0.251
0.230
false
false
IGHV6
IGKV12
Kappa
null
null
null
null
null
6sc7
B
null
0
A
protein
null
e3 ubiquitin-protein ligase rnf31
LIGASE
07/23/19
dAb3/HOIP-RBR-Ligand3
HOMO SAPIENS; SYNTHETIC CONSTRUCT
synthetic construct
null
homo sapiens
Tsai, Y.-C.I., Johansson, H., House, D., Rittinger, K.
2.56
X-RAY DIFFRACTION
0.267
0.224
false
true
IGHV3
null
null
null
null
null
null
null
7nis
F
null
0
null
null
null
null
VIRAL PROTEIN
02/13/21
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8192 core
CAMELIDAE MIXED LIBRARY; INFLUENZA A VIRUS (STRAIN A/BREVIG MISSION/1/1918 H1N1); STAPHYLOCOCCUS AUREUS; SYNTHETIC CONSTRUCT
camelidae mixed library
null
null
Keown, J.R., Carrique, L., Fodor, E., Grimes, J.M.
5.96
ELECTRON MICROSCOPY
null
null
false
true
IGHV1
null
null
null
null
null
null
null
3idy
B
C
0
A
protein
null
hiv-1 hxbc2 gp120 core
IMMUNE SYSTEM
07/22/09
Crystal structure of HIV-gp120 core in complex with CD4-binding site antibody b13, space group C2221
HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS
homo sapiens
homo sapiens
human immunodeficiency virus 1
Chen, L., Kwon, Y.D., Zhou, T., Wu, X., O'Dell, S., Cavacini, L., Hessell, A.J., Pancera, M., Tang, M., Xu, L., Yang, Z.Y., Zhang, M.Y., Arthos, J., Burton, D.R., Dimitrov, D.S., Nabel, G.J., Posner, M., Sodroski, J., Wyatt, R., Mascola, J.R., Kwong, P.D.
3.2
X-RAY DIFFRACTION
0.237
0.196
false
true
IGHV3
IGKV1
Kappa
0
-11.450945
SPR
null
TBD
6iw2
N
O
0
M
protein
null
envelope protein e
VIRAL PROTEIN/IMMUNE SYSTEM
12/04/18
Crystal structure of 5A ScFv in complex with YFV-17D sE in prefusion state
YELLOW FEVER VIRUS (STRAIN 17D VACCINE); HOMO SAPIENS
homo sapiens
homo sapiens
yellow fever virus (strain 17d vaccine)
Lu, X.S., Xiao, H.X., Li, S.H., Pang, X.F.
2.9
X-RAY DIFFRACTION
0.272
0.238
false
true
IGHV4
IGKV1
Kappa
null
null
null
null
null
6xv8
B
null
0
null
null
null
null
STRUCTURAL PROTEIN
01/21/20
Crystal structure of Megabody Mb-Nb207-c7HopQ_G10
LAMA GLAMA; HELICOBACTER PYLORI (STRAIN G27)
lama glama, helicobacter pylori (strain g27)
null
null
Steyaert, J., Uchanski, T., Fischer, B.
3.15
X-RAY DIFFRACTION
0.297
0.255
false
true
IGHV1
null
null
null
null
null
null
null
6bzv
C
D
0
J
peptide
null
e2 as412 peptide
IMMUNE SYSTEM
12/26/17
Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the GL precursor of the broadly neutralizing antibody 19B3
MUS MUSCULUS; SYNTHETIC CONSTRUCT
mus musculus
mus musculus
hepatitis c virus
Tzarum, N., Alemn, F., Wilson, I.A., Law, M.
2.654
X-RAY DIFFRACTION
0.241
0.199
false
true
IGHV3
IGKV3
Kappa
null
null
null
null
null
3hi5
H
L
0
null
null
null
null
IMMUNE SYSTEM
05/18/09
Crystal structure of Fab fragment of AL-57
HOMO SAPIENS
homo sapiens
homo sapiens
null
Zhang, H., Wang, J.
2.5
X-RAY DIFFRACTION
0.277
0.234
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
6bpe
H
I
0
G
protein
null
reticulocyte binding protein 2, putative
CELL INVASION
11/22/17
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to monoclonal antibody 6H1
PLASMODIUM VIVAX (STRAIN SALVADOR I); MUS MUSCULUS
mus musculus
mus musculus
plasmodium vivax (strain salvador i)
Gruszczyk, J., Chan, L.J., Tham, W.H.
3.34
X-RAY DIFFRACTION
0.367
0.318
false
false
IGHV5
IGKV6
Kappa
null
null
null
null
null
7f7e
C
L
0
E
protein
null
spike protein s1
VIRAL PROTEIN
06/29/21
SARS-CoV-2 S protein RBD in complex with A5-10 Fab
HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2
homo sapiens
homo sapiens
severe acute respiratory syndrome coronavirus2
Dou, Y., Wang, X., Wang, K., Liu, P., Lu, B.
2.49
X-RAY DIFFRACTION
0.256
0.214
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
5dtf
A
B
0
B
Hapten
5CT
Hypusine
IMMUNE SYSTEM
09/18/15
context-independent anti-hypusine antibody FabHpu98.61 in complex with hypusine
ORYCTOLAGUS CUNICULUS; SYNTHETIC CONSTRUCT
oryctolagus cuniculus
oryctolagus cuniculus
oryctolagus cuniculus
Zhai, Q., Carter, P.J.
1.9
X-RAY DIFFRACTION
0.254
0.212
false
true
IGHV1
IGKV1
Kappa
null
null
null
null
null
2bx5
null
K
0
null
null
null
null
ANTIBODY
07/22/05
Is FR1 the antibody's Achillies heel
ESCHERICHIA COLI
null
null
null
James, L.C.
2.7
X-RAY DIFFRACTION
0.290
0.250
false
true
null
IGKV1
Kappa
null
null
null
null
null
5xp1
null
G
0
null
null
null
null
IMMUNE SYSTEM
05/31/17
Structure of monomeric mutant of REI immunoglobulin light chain variable domain crystallized at pH 6
HOMO SAPIENS
null
homo sapiens
null
Mine, S., Nakamura, T., Uegaki, K., Hamada, D.
2.88
X-RAY DIFFRACTION
0.297
0.257
false
true
null
IGKV1
Kappa
null
null
null
null
null
3piq
E
F
0
null
null
null
null
IMMUNE SYSTEM
11/07/10
Crystal structure of human 2909 Fab, a quaternary structure-specific antibody against HIV-1
HOMO SAPIENS
homo sapiens
homo sapiens
null
Changela, A., Gorny, M.K., Zolla-Pazner, S., Kwong, P.D.
3.325
X-RAY DIFFRACTION
0.299
0.236
false
true
IGHV3
IGLV3
Lambda
null
null
null
null
null
6feq
F
E
0
A
protein
null
atp-binding cassette sub-family g member 2
MEMBRANE PROTEIN
01/03/18
Structure of inhibitor-bound ABCG2
HOMO SAPIENS; MUS MUSCULUS
mus musculus
mus musculus
homo sapiens
Jackson, S.M., Manolaridis, I., Kowal, J., Zechner, M., Altmann, K.H., Locher, K.P.
3.6
ELECTRON MICROSCOPY
null
null
false
true
IGHV3
IGKV13
Kappa
null
null
null
null
null
3mod
H
L
0
P
peptide
null
gp41 mper-derived peptide
IMMUNE SYSTEM
04/22/10
Crystal structure of the neutralizing HIV antibody 2F5 Fab fragment (recombinantly produced IgG) with 11 aa gp41 MPER-derived peptide
HOMO SAPIENS; SYNTHETIC CONSTRUCT
homo sapiens
null
homo sapiens
Nicely, N.I., Dennison, S.M., Kelsoe, G., Liao, H.-X., Alam, S.M., Haynes, B.F.
2.2
X-RAY DIFFRACTION
0.214
0.184
false
true
IGHV2
IGKV1
Kappa
null
null
null
null
null
3thm
H
L
0
F
protein
null
tumor necrosis factor receptor superfamily member 6
IMMUNE SYSTEM
08/19/11
Crystal structure of Fas receptor extracellular domain in complex with Fab EP6b_B01
HOMO SAPIENS
homo sapiens
homo sapiens
homo sapiens
Zuger, S., Stirnimann, C., Briand, C., Grutter, M.G.
2.1
X-RAY DIFFRACTION
0.221
0.183
false
true
IGHV4
IGLV1
Lambda
null
null
null
null
null
7mfa
M
N
0
null
null
null
null
IMMUNE SYSTEM
04/08/21
Crystal structure of antibody 10E8v4-P100fA+P100gA Fab
HOMO SAPIENS
homo sapiens
homo sapiens
null
Kwon, Y.D., Kwong, P.D.
2.4
X-RAY DIFFRACTION
0.286
0.238
false
true
IGHV3
IGLV3
Lambda
null
null
null
null
null
1ngy
B
A
0
null
null
null
null
IMMUNE SYSTEM
12/18/02
Chimeric Mature Fab 7g12-Apo
MUS MUSCULUS, HOMO SAPIENS
mus musculus, homo sapiens
mus musculus, homo sapiens
null
Yin, J., Andryski, S.A., Beuscher, A.B., Stevens, R.C., Schultz, P.G.
2.2
X-RAY DIFFRACTION
0.273
0.235
false
true
IGHV1
IGKV6
Kappa
null
null
null
null
null
7llk
G
H
0
E
protein
null
envelope glycoprotein gp120
IMMUNE SYSTEM/VIRAL PROTEIN
02/04/21
Cryo-EM structure of Q23.17_DS-SOSIP in complex with Glycan276-Dependent Broadly Neutralizing Antibody 179NC75 Fab
HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS
homo sapiens
homo sapiens
human immunodeficiency virus 1
Manne, K., Acharya, P.
4.8
ELECTRON MICROSCOPY
null
null
false
true
unknown
unknown
unknown
null
null
null
null
null
1xfp
A
null
0
L
protein
null
lysozyme c
IMMUNE SYSTEM/HYDROLASE
09/15/04
Crystal structure of the CDR2 germline reversion mutant of cAb-Lys3 in complex with hen egg white lysozyme
CAMELUS DROMEDARIUS; GALLUS GALLUS
camelus dromedarius
null
gallus gallus
De Genst, E., Handelberg, F., Van Meirhaeghe, A., Vynck, S., Loris, R., Wyns, L., Muyldermans, S.
1.5
X-RAY DIFFRACTION
0.216
0.201
false
true
IGHV1
null
null
null
null
null
null
null
6u02
D
C
0
B
protein
null
neuraminidase
VIRAL PROTEIN/IMMUNE SYSTEM
08/13/19
CryoEM-derived model of NA-63 Fab in complex with N9 Shanghai2
INFLUENZA A VIRUS (A/ENVIRONMENT/SHANGHAI/S1439/2013(H7N9)); HOMO SAPIENS
homo sapiens
homo sapiens
influenza a virus(a/environment/shanghai/s1439/2013(h7n9))
Ward, A.B., Turner, H.L., Zhu, X.
3.05
ELECTRON MICROSCOPY
null
null
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
6ca7
H
L
0
null
null
null
null
IMMUNE SYSTEM
01/29/18
Crystal structure of PCT64_13C, a strain specific anti-HIV antibody
HOMO SAPIENS
homo sapiens
homo sapiens
null
Murrell, S., Wilson, I.A.
1.643
X-RAY DIFFRACTION
0.190
0.169
false
true
IGHV3
IGKV3
Kappa
null
null
null
null
null
5a3i
G
H
0
E
protein
null
hemagglutinin
VIRAL PROTEIN
06/01/15
Crystal Structure of a Complex formed between FLD194 Fab and Transmissible Mutant H5 Haemagglutinin
INFLUENZA A VIRUS (A/VIETNAM/1203/2004(H5N1)); HOMO SAPIENS
homo sapiens
homo sapiens
influenza a virus (a/vietnam/1203/2004(h5n1))
Xiong, X., Corti, D., Liu, J., Pinna, D., Foglierini, M., Calder, L.J., Martin, S.R., Lin, Y.P., Walker, P.A., Collins, P.J., Monne, I., Suguitan Jr, A.L., Santos, C., Temperton, N.J., Subbarao, K., Lanzavecchia, A., Gamblin, S.J., Skehel, J.J.
2.89
X-RAY DIFFRACTION
0.277
0.244
false
false
IGHV5
IGKV2
Kappa
null
null
null
null
null
5obf
H
L
0
null
null
null
null
IMMUNE SYSTEM
06/26/17
fAb. AbVance: increasing our knowledge of antibody structural space to enable faster and better decision-making in antibody drug discovery.
MUS MUSCULUS
mus musculus
mus musculus
null
Vicentini, G., Convery, M.A.
1.92
X-RAY DIFFRACTION
0.210
0.174
false
true
IGHV14
IGKV2
Kappa
null
null
null
null
null
4yfl
H
L
0
G
protein
null
envelope glycoprotein gp160,envelope glycoprotein gp160,envelope glycoprotein gp160
IMMUNE SYSTEM
02/25/15
Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 1B2530 in complex with HIV-1 clade A/E 93TH057 gp120
HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS
homo sapiens
homo sapiens
human immunodeficiency virus 1
Acharya, P., Zhou, T., Moquin, S., Kwong, P.D.
3.387
X-RAY DIFFRACTION
0.326
0.268
false
true
unknown
IGLV1
Lambda
null
null
null
null
null
6iyn
A
null
5
null
null
null
null
AFLATOXIN B1-BINDING PROTEIN
12/17/18
Solution structure of camelid nanobody Nb26 against aflatoxin B1
VICUGNA PACOS
vicugna pacos
null
null
Nie, Y., He, T., Zhu, J., Li, S.L., Hu, R., Yang, Y.H.
NOT
SOLUTION NMR
null
null
false
true
IGHV1
null
null
null
null
null
null
null
5d1z
D
C
0
I
protein
null
iron-regulated surface determinant protein b
IMMUNE SYSTEM
08/04/15
IsdB NEAT1 bound by clone D4-10
HOMO SAPIENS; STAPHYLOCOCCUS AUREUS (STRAIN MSSA476)
homo sapiens
homo sapiens
staphylococcus aureus (strain mssa476)
Deng, X.
3.17
X-RAY DIFFRACTION
0.287
0.233
false
true
IGHV4
IGKV1
Kappa
null
null
null
null
null
7tb8
H
L
0
A
protein
null
spike glycoprotein
VIRAL PROTEIN/Immune System
12/21/21
Cryo-EM structure of SARS-CoV-2 spike in complex with antibodies B1-182.1 and A19-61.1
SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS
homo sapiens
homo sapiens
severe acute respiratory syndrome coronavirus2
Zhou, T., Tsybovsky, T., Kwong, P.D.
2.83
ELECTRON MICROSCOPY
null
null
false
true
IGHV1
IGKV3
Kappa
null
null
null
null
null
1dqq
B
A
0
null
null
null
null
IMMUNE SYSTEM
01/04/00
CRYSTAL STRUCTURE OF ANTI-LYSOZYME ANTIBODY HYHEL-63
MUS MUSCULUS
mus musculus
mus musculus
null
Li, H., Mariuzza, R.A.
1.8
X-RAY DIFFRACTION
0.255
0.210
false
true
IGHV3
IGKV5
Kappa
null
null
null
null
null
7mdw
A
null
0
R
protein
null
spike protein s1
VIRAL PROTEIN/Immune System
04/06/21
CryoEM structure of SARS-CoV-2 RBD in complex with nanobodies Nb21 and Nb105
LAMA GLAMA; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2
lama glama
null
severe acute respiratory syndrome coronavirus2
Huang, W., Taylor, D.J.
3.58
ELECTRON MICROSCOPY
null
null
false
true
IGHV1
null
null
null
null
null
null
null
4nbz
D
null
0
C
protein
null
tcda
IMMUNE SYSTEM
10/23/13
Crystal Structure of TcdA-A1 Bound to A26.8 VHH
CLOSTRIDIUM DIFFICILE; LAMA GLAMA
lama glama
null
clostridium difficile
Murase, T., Eugenio, L., Schorr, M., Hussack, G., Tanha, J., Kitova, E.N., Klassen, J.S., Ng, K.K.S.
1.75
X-RAY DIFFRACTION
0.247
0.206
false
true
IGHV1
null
null
null
null
null
null
null
2ajv
H
L
0
L
Hapten
COC
COCAINE
IMMUNE SYSTEM
08/02/05
Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with Cocaine
MUS MUSCULUS
mus musculus
mus musculus
mus musculus
Zhu, X., Wilson, I.A.
1.5
X-RAY DIFFRACTION
0.227
0.182
false
false
IGHV3
IGKV2
Kappa
null
null
null
null
null
4fqr
e
f
0
E
protein
null
broadly neutralizing antibody c05, heavy chain
VIRAL PROTEIN/IMMUNE SYSTEM
06/25/12
Crystal structure of broadly neutralizing antibody C05 bound to H3 influenza hemagglutinin
INFLUENZA A VIRUS; HOMO SAPIENS
homo sapiens
homo sapiens
influenza a virus
Ekiert, D.C., Wilson, I.A.
4.1
X-RAY DIFFRACTION
0.334
0.309
false
false
IGHV3
IGKV1
Kappa
0
-9.549709
SPR
null
TBD
1nmc
H
L
0
N
protein
null
neuraminidase
COMPLEX (SINGLE-CHAIN ANTIBODY/ANTIGEN)
12/21/97
COMPLEX BETWEEN NC10 ANTI-INFLUENZA VIRUS NEURAMINIDASE SINGLE CHAIN ANTIBODY WITH A 15 RESIDUE LINKER AND INFLUENZA VIRUS NEURAMINIDASE
INFLUENZA A VIRUS; MUS MUSCULUS
mus musculus
mus musculus
influenza a virus
Malby, R.L., Mccoy, A.J., Kortt, A.A., Hudson, P.J., Colman, P.M.
2.5
X-RAY DIFFRACTION
0.260
0.220
false
true
IGHV1
IGKV10
Kappa
null
null
null
null
null
5cus
I
M
0
B
protein
null
receptor tyrosine-protein kinase erbb-3
TRANSFERASE
07/25/15
Crystal Structure of sErbB3-Fab3379 Complex
HOMO SAPIENS
homo sapiens
homo sapiens
homo sapiens
Lee, S., Schlessinger, J.
3.2
X-RAY DIFFRACTION
0.278
0.252
false
true
IGHV3
IGLV1
Lambda
null
null
null
null
null
7sp7
B
null
0
A
protein
null
hyaluronan synthase
MEMBRANE PROTEIN
11/02/21
Chlorella virus hyaluronan synthase inhibited by UDP
PARAMECIUM BURSARIA CHLORELLA VIRUS CZ-2; LAMA GLAMA
lama glama
null
paramecium bursaria chlorella virus cz-2
Maloney, F.P., Kuklewicz, J., Zimmer, J.
3.1
ELECTRON MICROSCOPY
null
null
false
true
IGHV1
null
null
null
null
null
null
null
4zyk
H
L
0
null
null
null
null
IMMUNE SYSTEM
05/21/15
Crystal Structure of Quaternary-Specific RSV-Neutralizing Human Antibody AM14
HOMO SAPIENS
homo sapiens
homo sapiens
null
Gilman, M.S.A., McLellan, J.S.
2.0
X-RAY DIFFRACTION
0.226
0.186
false
true
IGHV3
IGKV1
Kappa
null
null
null
null
null
6w1c
L
P
0
H
protein
null
e2 glycoprotein
VIRUS/IMMUNE SYSTEM
03/04/20
Human mAbs broadly protect against infection of arthritiogenic alphaviruses by recognizing conserved elements of the MXR8 receptor binding domain
MAYARO VIRUS (STRAIN BRAZIL); HOMO SAPIENS
homo sapiens
homo sapiens
mayaro virus (strain brazil)
Miller, A.S., Kuhn, R.J.
5.3
ELECTRON MICROSCOPY
null
null
false
true
IGHV9
IGLV1
Lambda
null
null
null
null
null
7dk6
a
b
0
A
protein
null
the heavy chain of 2h2 fab
VIRAL PROTEIN
11/23/20
S-2H2-F2 structure, two RBDs are up and one RBD is down, each up RBD binds with a 2H2 Fab.
SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; MUS MUSCULUS
mus musculus
mus musculus
severe acute respiratory syndrome coronavirus2
Cong, Y., Wang, Y.F.
4.3
ELECTRON MICROSCOPY
null
null
false
false
IGHV2
IGKV3
Kappa
null
null
null
null
null
5mub
F
G
0
H
peptide
null
triple-helical peptide containing the citrullinated c1epitope of collagen type ii,collagen alpha-1(ii) chain,triple-helical peptide containing the citrullinated c1 epitope of collagen type ii
IMMUNE SYSTEM
01/13/17
ACC1 Fab fragment in complex with citrullinated C1 epitope of CII (CG05)
MUS MUSCULUS; SYNTHETIC CONSTRUCT
mus musculus
mus musculus
mus musculus
Dobritzsch, D., Holmdahl, R., Ge, C.
3.1
X-RAY DIFFRACTION
0.264
0.231
false
false
IGHV6
IGKV3
Kappa
null
null
null
null
null
2bx5
null
F
0
null
null
null
null
ANTIBODY
07/22/05
Is FR1 the antibody's Achillies heel
ESCHERICHIA COLI
null
null
null
James, L.C.
2.7
X-RAY DIFFRACTION
0.290
0.250
false
true
null
IGKV1
Kappa
null
null
null
null
null
5nml
I
null
0
null
null
null
null
IMMUNE SYSTEM
04/06/17
Nb36 Ser85Cys with Hg bound
LAMA GLAMA
lama glama
null
null
Hansen, S.B., Andersen, K.R., Laursen, N.S., Andersen, G.R.
2.5
X-RAY DIFFRACTION
0.265
0.238
false
true
IGHV1
null
null
null
null
null
null
null
1u8m
B
A
0
C
peptide
null
gp41 peptide
IMMUNE SYSTEM
08/06/04
Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide ELDKYAS
HOMO SAPIENS; SYNTHETIC CONSTRUCT
homo sapiens
homo sapiens
human immunodeficiency virus 1
Bryson, S., Julien, J.-P., Hynes, R.C., Pai, E.F.
2.4
X-RAY DIFFRACTION
0.225
0.218
false
false
IGHV2
IGKV1
Kappa
null
null
null
null
null
4tuk
H
L
0
I
peptide
null
peptide2
IMMUNE SYSTEM
06/24/14
Crystal structure of monoclonal antibody against neuroblastoma associated antigen.
MUS MUSCULUS; SYNTHETIC CONSTRUCT
mus musculus
mus musculus
phage #d
Golik, P., Grudnik, P., Dubin, G., Horwacik, I., Zdzalik, M., Rokita, H.
1.6
X-RAY DIFFRACTION
0.206
0.162
false
true
IGHV1
IGKV1
Kappa
null
null
null
null
null
2vxs
H
L
0
B
protein
null
interleukin-17a
CYTOKINE
07/09/08
Structure of IL-17A in complex with a potent, fully human neutralising antibody
HOMO SAPIENS
homo sapiens
homo sapiens
homo sapiens
Gerhardt, S., Hargreaves, D., Pauptit, R.A., Davies, R.A., Russell, C., Welsh, F., Tuske, S.J., Coales, S.J., Hamuro, Y., Needham, M.R.C., Langham, C., Barker, W., Bell, P., Aziz, A., Smith, M.J., Dawson, S., Abbott, W.M.
2.63
X-RAY DIFFRACTION
0.264
0.213
false
true
IGHV3
IGLV6
Lambda
0
-11.83
SPR
null
19835883
2itd
A
B
0
C
protein
null
voltage-gated potassium channel
MEMBRANE PROTEIN
10/19/06
Potassium Channel KcsA-Fab complex in Barium Chloride
STREPTOMYCES LIVIDANS; MUS MUSCULUS
mus musculus
mus musculus
streptomyces lividans
Lockless, S.W., Zhou, M., MacKinnon, R.
2.7
X-RAY DIFFRACTION
0.261
0.241
false
false
IGHV1
IGKV5
Kappa
null
null
null
null
null
7p5w
J
null
0
D
protein
null
volume-regulated anion channel subunit lrrc8a
MEMBRANE PROTEIN
07/15/21
Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb2
MUS MUSCULUS; SYNTHETIC CONSTRUCT
synthetic construct
null
mus musculus
Deneka, D., Rutz, S., Sawicka, M.
3.5
ELECTRON MICROSCOPY
null
null
false
true
IGHV1
null
null
null
null
null
null
null
3v6f
C
D
0
null
null
null
null
IMMUNE SYSTEM
12/19/11
Crystal Structure of an anti-HBV e-antigen monoclonal Fab fragment (e6), unbound
MUS MUSCULUS
mus musculus
mus musculus
null
Dimattia, M.A., Watts, N.R., Stahl, S.J., Grimes, J.M., Steven, A.C., Stuart, D.I., Wingfield, P.T.
2.52
X-RAY DIFFRACTION
0.220
0.179
false
false
IGHV5
IGKV8
Kappa
null
null
null
null
null