pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
4grw | H | null | 0 | B | protein | null | interleukin-12 subunit beta | IMMUNE SYSTEM | 08/27/12 | Structure of a complex of human IL-23 with 3 Nanobodies (Llama vHHs) | LLAMA GLAMA; HOMO SAPIENS; SYNTHETIC CONSTRUCT | lama glama | null | homo sapiens | Desmyter, A., Spinelli, S., Button, C., Saunders, M., de Haard, H., Rommelaere, H., Union, A., Cambillau, C. | 2.55 | X-RAY DIFFRACTION | 0.218 | 0.183 | false | true | IGHV1 | null | null | null | null | null | null | null |
7o2z | H | L | 0 | P | peptide | null | p/a#1 epitope peptide | IMMUNE SYSTEM | 04/01/21 | Crystal structure of the anti-PAS Fab 2.2 in complex with its epitope peptide | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | synthetic construct | Schilz, J., Schiefner, A., Skerra, A. | 2.55 | X-RAY DIFFRACTION | 0.238 | 0.195 | false | true | IGHV8 | IGKV8 | Kappa | null | null | null | null | null |
6apd | H | I | 0 | B | protein | null | fusion glycoprotein f0,envelope glycoprotein | IMMUNE SYSTEM | 08/17/17 | Crystal structure of RSV F bound by AM22 and the infant antibody ADI-19425 | RESPIRATORY SYNCYTIAL VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | respiratory syncytial virus, humanimmunodeficiency virus 1 | Wrapp, D., McLellan, J.S. | 4.1 | X-RAY DIFFRACTION | 0.256 | 0.204 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7lez | D | E | 0 | B | protein | null | arginase-1 | HYDROLASE/IMMUNE SYSTEM | 01/15/21 | Trimeric human Arginase 1 in complex with mAb1 - 2 hArg:2 mAb1 complex | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Gomez-Llorente, Y., Scapin, G., Palte, R.L. | 4.15 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7d00 | J | N | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN | 09/09/20 | S protein of SARS-CoV-2 in complex bound with FabP5A-1B8 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Yan, R.H., Zhang, Y.Y., Li, Y.N., Zhou, Q. | 3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6p95 | F | G | 0 | b | B | protein | protein | NA | NA | unknown | pre-glycoprotein polyprotein gp complex | viral protein/immune system | 06/09/19 | Structure of Lassa virus glycoprotein in complex with Fab 25.6A | LASSA VIRUS; HOMO SAPIENS; LASSA VIRUS (STRAIN MOUSE/SIERRA LEONE/JOSIAH/1976) | homo sapiens | homo sapiens | lassa virus (strain mouse/sierraleone/josiah/1976) | lassa virus | Saphire, E.O., Hastie, K.M. | 3.5 | X-RAY DIFFRACTION | 0.247 | 0.205 | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
1ieh | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 04/09/01 | SOLUTION STRUCTURE OF A SOLUBLE SINGLE-DOMAIN ANTIBODY WITH HYDROPHOBIC RESIDUES TYPICAL OF A VL/VH INTERFACE | LAMA GLAMA | lama glama | null | null | Vranken, W., Tolkatchev, D., Xu, P., Tanha, J., Chen, Z., Narang, S., Ni, F. | NOT | SOLUTION NMR | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
7qn5 | F | null | 0 | C | protein | null | gamma-aminobutyric acid receptor subunit beta-3 | MEMBRANE PROTEIN | 12/20/21 | Cryo-EM structure of human full-length extrasynaptic alpha4beta3delta GABA(A)R in complex with nanobody Nb25 | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Sente, A., Desai, R., Naydenova, K., Malinauskas, T., Jounaidi, Y., Miehling, J., Zhou, X., Masiulis, S., Hardwick, S.W., Chirgadze, D.Y., Miller, K.W., Aricescu, A.R. | 2.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
4zg1 | B | null | 0 | null | null | null | null | PROTEIN BINDING | 04/22/15 | Crystal structure of a nanobody raised against KDM5b | LAMA GLAMA | lama glama | null | null | Wiuf, A., Kristensen, O., Gajhede, M. | 1.85 | X-RAY DIFFRACTION | 0.235 | 0.186 | false | true | IGHV1 | null | null | null | null | null | null | null |
5c8j | G | H | 0 | K | protein | null | protein mj0480 | MEMBRANE PROTEIN | 06/25/15 | A YidC-like protein in the archaeal plasma membrane | HOMO SAPIENS; METHANOCALDOCOCCUS JANNASCHII (STRAIN ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) | homo sapiens | homo sapiens | methanocaldococcus jannaschii (strain atcc43067 / dsm 2661 / jal-1 / jcm 10045 / nbrc 100440) | Borowska, M.T., Dominik, P.K., Anghel, S.A., Kossiakoff, A.A., Keenan, R.J. | 3.502 | X-RAY DIFFRACTION | 0.302 | 0.253 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
1bzq | L | null | 0 | A | protein | null | protein (rnase a) | HYDROLASE/IMMUNE SYSTEM | 11/03/98 | COMPLEX OF A DROMEDARY SINGLE-DOMAIN VHH ANTIBODY FRAGMENT WITH RNASE A | CAMELUS DROMEDARIUS; BOS TAURUS | camelus dromedarius | null | bos taurus | Decanniere, K., Desmyter, A., Gahroudhi, M., Lauwereys, M., Muyldermans, S., Wyns, L. | 2.8 | X-RAY DIFFRACTION | 0.282 | 0.222 | false | true | IGHV1 | null | null | null | null | null | null | null |
6ncp | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 12/11/18 | Crystal structure of HIV-1 broadly neutralizing antibody ACS202 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | null | Yuan, M., Wilson, I.A. | 2.76 | X-RAY DIFFRACTION | 0.256 | 0.222 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4ene | E | F | 0 | B | protein | null | h(+)/cl(-) exchange transporter clca | TRANSPORT PROTEIN | 04/13/12 | Structure of the N- and C-terminal trimmed ClC-ec1 Cl-/H+ antiporter and Fab Complex | ESCHERICHIA COLI K-12; MUS MUSCULUS | mus musculus | mus musculus | escherichia coli k-12 | Hyun-Ho Lim, Shane, T., Miller, C. | 2.4 | X-RAY DIFFRACTION | 0.278 | 0.239 | false | true | IGHV4 | IGKV4 | Kappa | null | null | null | null | null |
4i3r | H | L | 0 | G | protein | null | outer domain of hiv-1 gp120 (ker2018 od4.2.2) | Viral Protein/Immune System | 11/26/12 | Crystal structure of the outer domain of HIV-1 gp120 in complex with VRC-PG04 space group P3221 | HUMAN IMMUNODEFICIENCY VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus | Joyce, M.G., Biertumpfel, C., Nabel, G.J., Kwong, P.D. | 3.0 | X-RAY DIFFRACTION | 0.245 | 0.183 | false | true | unknown | unknown | unknown | 0 | -10.810888 | SPR | null | TBD |
5tdo | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 09/19/16 | Crystal structure of the Fab fragment of anti-HER2 antibody 4D5 with redesigned heavy and light chain interfaces | HOMO SAPIENS | homo sapiens | homo sapiens | null | Yin, Y., Carter, P.J. | 1.61 | X-RAY DIFFRACTION | 0.267 | 0.237 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7a6f | C | B | 0 | A | protein | null | multidrug resistance protein 1 | TRANSPORT PROTEIN | 08/25/20 | Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and zosuquidar | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Nosol, K., Locher, K.P. | 3.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
7kmg | A | B | 0 | C | protein | null | spike protein s1 | IMMUNE SYSTEM/VIRAL PROTEIN | 11/02/20 | LY-CoV555 neutralizing antibody against SARS-CoV-2 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Hendle, J., Pustilnik, A., Sauder, J.M., Coleman, K.A., Boyles, J.S., Dickinson, C.D. | 2.16 | X-RAY DIFFRACTION | 0.257 | 0.209 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
2x89 | C | null | 0 | E | G | protein | protein | NA | NA | beta-2-microglobulin | beta-2-microglobulin | IMMUNE SYSTEM | 03/07/10 | Structure of the Beta2_microglobulin involved in amyloidogenesis | HOMO SAPIENS; CAMELUS DROMEDARIUS | homo sapiens | null | homo sapiens | homo sapiens | Domanska, K., Srinivasan, V., Vanderhaegen, S., Pardon, E., Marquez, J.A., Bellotti, V., Wyns, L., Steyaert, J. | 2.16 | X-RAY DIFFRACTION | 0.26691 | 0.23813 | false | true | IGHV3 | null | null | 0 | -10.03 | SPR | null | 21220305 |
2kqn | null | A | 4 | null | null | null | null | IMMUNE SYSTEM | 11/11/09 | Solution structure of the AL-09 H87Y immunoglobulin light chain variable domain | HOMO SAPIENS | null | homo sapiens | null | Volkman, B.F., Peterson, F.C., Ramirez-Alvarado, M., Baden, E.M. | NOT | SOLUTION NMR | null | null | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
4plj | D | C | 0 | B | protein | null | capsid protein | VIRAL PROTEIN/IMMUME SYSTEM | 05/18/14 | Hepatitis E Virus E2s domain (Genotype IV) in complex with a neutralizing antibody 8G12 | HEPATITIS E VIRUS; MUS MUSCULUS | mus musculus | mus musculus | hepatitis e virus | Tang, X.H., Li, S.W., Sivaraman, J. | 2.3 | X-RAY DIFFRACTION | 0.242 | 0.187 | false | false | IGHV1 | IGKV12 | Kappa | null | null | null | null | null |
6krz | D | E | 0 | A | protein | null | adiponectin receptor protein 1 | MEMBRANE PROTEIN/IMMUNE SYSTEM | 08/22/19 | Crystal structure of the human adiponectin receptor 1 D208A mutant | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Tanabe, H., Fujii, Y., Okada-Iwabu, M., Iwabu, M., Yamauchi, T., Kadowaki, T., Yokoyama, S. | 3.05 | X-RAY DIFFRACTION | 0.273 | 0.216 | false | true | IGHV1 | IGKV12 | Kappa | null | null | null | null | null |
3upc | I | null | 0 | null | null | null | null | IMMUNE SYSTEM | 11/17/11 | A general strategy for the generation of human antibody variable domains with increased aggregation resistance | HOMO SAPIENS | homo sapiens | null | null | Dudgeon, K., Rouet, R., Kokmeijer, I., Langley, D.B., Christ, D. | 2.8 | X-RAY DIFFRACTION | 0.247 | 0.209 | false | true | IGHV3 | null | null | null | null | null | null | null |
7cvs | C | D | 0 | A | protein | null | h(+)/cl(-) exchange transporter clca | TRANSPORT PROTEIN | 08/27/20 | Crystal structure of the C85A/L194A mutant CLC-ec1 with Fab fragment | ESCHERICHIA COLI MS 198-1; MUS MUSCULUS | mus musculus | mus musculus | escherichia coli ms 198-1 | Park, K., Mersch, K., Robertson, J., Lim, H.-H. | 3.01 | X-RAY DIFFRACTION | 0.255 | 0.201 | false | true | IGHV4 | IGKV4 | Kappa | null | null | null | null | null |
3qxv | B | null | 0 | B | Hapten | MTX | METHOTREXATE | IMMUNE SYSTEM | 03/02/11 | Structure of an Anti-Methotrexate CDR1-4 Graft VHH Antibody in Complex with Methotrexate | LAMA GLAMA | lama glama | null | lama glama | Fanning, S.W., Horn, J.R. | 2.5 | X-RAY DIFFRACTION | 0.279 | 0.230 | false | true | IGHV1 | null | null | 0 | -11.45684 | Unknown | null | TBD |
6cnk | G | F | 0 | C | B | protein | protein | NA | NA | neuronal acetylcholine receptor subunit beta-2 | neuronal acetylcholine receptor subunit alpha-4 | TRANSPORT PROTEIN | 03/08/18 | Structure of the 3alpha2beta stiochiometry of the human Alpha4Beta2 nicotinic receptor | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | homo sapiens | Walsh Jr, R.M., Roh, S.H., Gharpure, A., Morales-Perez, C.L., Hibbs, R.E. | 3.7 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7v0v | A | null | 9 | null | null | null | null | IMMUNE SYSTEM | 05/11/22 | GFP Nanobody NMR Structure | SYNTHETIC CONSTRUCT | synthetic construct | null | null | Mueller, G.A. | NOT | SOLUTION NMR | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
7lzp | C | null | 0 | A | protein | null | botulinum neurotoxin a light chain | ANTITOXIN | 03/10/21 | LC/A-JPU-B9-JPU-A11-JPU-G11 | CLOSTRIDIUM BOTULINUM; VICUGNA PACOS | vicugna pacos | null | clostridium botulinum | Lam, K., Jin, R. | 2.86 | X-RAY DIFFRACTION | 0.273 | 0.235 | false | true | IGHV1 | null | null | null | null | null | null | null |
5mv3 | L | M | 0 | N | peptide | null | synthetic peptide containing the cii583-591 epitope ofcollagen type ii,collagen alpha-1(ii) chain,synthetic peptide containing the cii583-591 epitope of collagen type ii, | IMMUNE SYSTEM | 01/15/17 | ACC1 Fab fragment in complex with CII583-591 (CG10) | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | mus musculus | Dobritzsch, D., Holmdahl, R., Ge, C. | 2.95 | X-RAY DIFFRACTION | 0.261 | 0.202 | false | false | IGHV6 | IGKV3 | Kappa | null | null | null | null | null |
7kew | I | L | 0 | C | protein | null | spike glycoprotein 1 | VIRAL PROTEIN/IMMUNE SYSTEM | 10/13/20 | Bundibugyo virus GP (mucin deleted) bound to antibody Fab BDBV-43 | BUNDIBUGYO EBOLAVIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | bundibugyo ebolavirus | Murin, C.D., Ward, A.B. | 4.16 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7r6w | H | L | 0 | R | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 06/23/21 | SARS-CoV-2 spike receptor-binding domain (RBD) in complex with S2X35 Fab and S309 Fab | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Snell, G., Czudnochowski, N., Hernandez, P., Nix, J.C., Croll, T.I., Corti, D., Cameroni, E., Pinto, D., Beltramello, M. | 1.83 | X-RAY DIFFRACTION | 0.232 | 0.211 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
4x7t | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 12/09/14 | Structure of Omalizumab Fab fragment, crystal form 2 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Jensen, R.K., Andersen, G.R. | 3.0 | X-RAY DIFFRACTION | 0.237 | 0.193 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7pij | H | L | 0 | null | null | null | null | MEMBRANE PROTEIN | 08/20/21 | Structure of Staphylococcus capitis divalent metal ion transporter (DMT) by NabFab-fiducial assisted cryo-EM | SYNTHETIC CONSTRUCT; STAPHYLOCOCCUS CAPITIS; LAMA GLAMA | synthetic construct | synthetic construct | null | Bloch, J.S., Mukherjee, S., Kowal, J., Kossiakoff, A.A., Locher, K.P. | 3.47 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7o85 | null | B | 0 | A | protein | null | protective antigen pa-63 | TOXIN | 04/14/21 | Anthrax toxin prepore in complex with the neutralizing Fab cAb29 | BACILLUS ANTHRACIS; MUS MUSCULUS | null | mus musculus | bacillus anthracis | Hoelzgen, F., Zalk, R., Alcalay, R., Cohen-Schwartz, S., Garau, G., Shahar, A., Mazor, O., Frank, G.A. | 3.3 | ELECTRON MICROSCOPY | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
5ifj | A | B | 0 | C | peptide | null | peptide pro-leu-gln-pro-glu-gln-pro-phe-pro | IMMUNE SYSTEM | 02/26/16 | Crystal structure of anti-gliadin 1002-1E01 Fab fragment in complex of peptide PLQPEQPFP | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | triticum aestivum | Chen, X., Zhao, Y., Harlos, K., Snir, O., Sollid, L.M. | 2.35 | X-RAY DIFFRACTION | 0.241 | 0.205 | false | true | IGHV3 | IGLV4 | Lambda | null | null | null | null | null |
5a1z | I | J | 0 | E | protein | null | envelope protein | null | 05/06/15 | Cryo-EM structure of Dengue virus serotype 2 strain PVP94-07 complexed with human antibody 2D22 Fab at 37 degrees C | DENGUE VIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | dengue virus 2 | Fibriansah, G., Ibarra, K.D., Ng, T.S., Smith, S.A., Tan, J.L., Lim, X.N., Ooi, J.S.G., Kostyuchenko, V.A., Wang, J., de Silva, A.M., Harris, E., Crowe Jr, J.E., Lok, S.M. | 6.9 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7b18 | I | null | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN | 11/24/20 | SARS-CoV-spike bound to two neutralising nanobodies | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; LAMA GLAMA; VICUGNA PACOS | vicugna pacos | null | severe acute respiratory syndrome coronavirus2 | Hallberg, B.M., Das, H. | 2.62 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
4xpa | H | L | 0 | A | protein | null | transporter | transport protein/inhibitor | 01/16/15 | X-ray structure of Drosophila dopamine transporter bound to 3,4dichlorophenethylamine | DROSOPHILA MELANOGASTER; MUS MUSCULUS | mus musculus | mus musculus | drosophila melanogaster | Aravind, P., Wang, K., Gouaux, E. | 2.95 | X-RAY DIFFRACTION | 0.255 | 0.230 | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
4hxa | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 11/09/12 | Crystal structure of 13D9 FAB | MUS MUSCULUS | mus musculus | mus musculus | null | Johal, A.R., Jarrell, H.C., Khieu, N.H., Letts, J.A., Landry, R.C., Jachymek, W., Yang, Q., Jennings, H.J., Brisson, J.R., Evans, S.V. | 2.06 | X-RAY DIFFRACTION | 0.286 | 0.213 | false | false | IGHV13 | IGKV4 | Kappa | null | null | null | null | null |
6vc9 | H | L | 0 | A | protein | null | 5'-nucleotidase, ecto (cd73), isoform cra_a | IMMUNE SYSTEM | 12/20/19 | TB19 complex | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Zhou, Y.F., Lord, D.M. | 2.25 | X-RAY DIFFRACTION | 0.279 | 0.237 | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
3vg0 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 01/10/12 | Antibody Fab fragment | MUS MUSCULUS | mus musculus | mus musculus | null | Carpenter, B., Hemsworth, G.R., Ross, R.J., Artymiuk, P.J. | 2.27 | X-RAY DIFFRACTION | 0.260 | 0.190 | false | false | IGHV2 | IGKV6 | Kappa | null | null | null | null | null |
7eyc | H | L | 0 | P | peptide | null | acetylated tau peptide | IMMUNE SYSTEM | 05/30/21 | Crystal structure of Tau and acetylated tau peptide antigen | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | synthetic construct | Hong, M., Park, J. | 2.49 | X-RAY DIFFRACTION | 0.245 | 0.192 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
6jhr | E | D | 0 | C | protein | null | vp3 | VIRUS | 02/18/19 | The cryo-EM structure of HAV bound to a neutralizing antibody-F6 | HUMAN HEPATITIS A VIRUS HU/AUSTRALIA/HM175/1976; MUS MUSCULUS | mus musculus | mus musculus | human hepatitis a virushu/australia/hm175/1976 | Cao, L., Liu, P., Yang, P., Gao, Q., Li, H., Sun, Y., Zhu, L., Lin, J., Su, D., Rao, Z., Wang, X. | 3.68 | ELECTRON MICROSCOPY | null | null | false | false | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
2fx8 | H | L | 0 | P | peptide | null | fragment of hiv glycoprotein (gp41) | IMMUNE SYSTEM | 02/03/06 | Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with an aib-induced peptide encompassing the 4e10 epitope on gp41 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | null | Cardoso, R.M.F., Brunel, F.M., Ferguson, S., Burton, D.R., Dawson, P.E., Wilson, I.A. | 2.2 | X-RAY DIFFRACTION | 0.283 | 0.235 | false | true | IGHV1 | IGKV3 | Kappa | 0 | -8.89 | SPR | null | 17125793 |
7wph | H | L | 0 | B | protein | null | spike protein s1 | PROTEIN BINDING | 01/23/22 | SARS-CoV2 RBD bound to Fab06 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Lin, J.Q., El Sahili, A., Lescar, J. | 2.89 | X-RAY DIFFRACTION | 0.269 | 0.229 | false | true | IGHV4 | IGLV2 | Lambda | null | null | null | null | null |
3ogc | A | B | 0 | C | protein | null | voltage-gated potassium channel | MEMBRANE PROTEIN | 08/16/10 | KcsA E71A variant in presence of Na+ | MUS MUSCULUS; STREPTOMYCES LIVIDANS | mus musculus | mus musculus | streptomyces lividans | McCoy, J.G., Nimigean, C.M. | 3.8 | X-RAY DIFFRACTION | 0.283 | 0.247 | false | true | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
1maj | null | A | 0 | null | null | null | null | IMMUNOGLOBULIN | 09/16/93 | SOLUTION STRUCTURE OF AN ISOLATED ANTIBODY VL DOMAIN | MUS MUSCULUS | null | mus musculus | null | Constantine, K.L., Friedrichs, M.S., Metzler, W.J., Wittekind, M., Hensley, P., Mueller, L. | NOT | SOLUTION NMR | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
4i18 | H | L | 0 | C | protein | null | prolactin receptor | CYTOKINE, SIGNALING PROTEIN | 11/20/12 | Crystal structure of human prolactin receptor complexed with Fab fragment | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Duguid, E.M., Mukherjee, S., Kouadio, J.L. | 3.238 | X-RAY DIFFRACTION | 0.246 | 0.191 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -11.257486 | SPR | null | TBD |
4oii | I | M | 0 | B | protein | null | non-structural protein ns1 | VIRAL PROTEIN/IMMUNE SYSTEM | 01/19/14 | West Nile Virus NS1 in complex with neutralizing 22NS1 antibody Fab | WEST NILE VIRUS; MUS MUSCULUS | mus musculus | mus musculus | west nile virus | Edeling, M.A., Fremont, D.H., Center for Structural Genomics of Infectious Diseases (CSGID) | 3.0 | X-RAY DIFFRACTION | 0.265 | 0.214 | false | true | IGHV1 | IGKV12 | Kappa | null | null | null | null | null |
7tty | H | L | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 02/02/22 | Crystal structure of potent neutralizing antibody 10-40 in complex with bat WIV1 receptor-binding domain | BAT SARS-LIKE CORONAVIRUS WIV1; HOMO SAPIENS | homo sapiens | homo sapiens | bat sars-like coronavirus wiv1 | Reddem, E.R., Shapiro, L. | 3.11 | X-RAY DIFFRACTION | 0.329 | 0.235 | false | true | IGHV4 | IGLV6 | Lambda | null | null | null | null | null |
6rlo | G | H | 0 | L | protein | null | cd9 antigen | IMMUNE SYSTEM | 05/02/19 | Crystal structure of AT1412dm Fab fragment in complex with CD9 large extracellular loop | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Neviani, V., Pearce, N.M., Pos, W., Schotte, R., Spits, H., Gros, P. | 2.2 | X-RAY DIFFRACTION | 0.287 | 0.254 | false | true | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
6xpr | B | C | 0 | A | protein | null | hemagglutinin | VIRAL PROTEIN/IMMUNE SYSTEM | 07/08/20 | Human antibody D2 H1-1/H3-1 H3 in complex with the influenza hemagglutinin head domain of A/Texas/50/2012(H3N2) | INFLUENZA A VIRUS (A/TEXAS/50/2012(H3N2)); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus (a/texas/50/2012(h3n2)) | McCarthy, K.R., Harrison, S.C., Lee, J. | 4.092 | X-RAY DIFFRACTION | 0.298 | 0.252 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6h06 | A | B | 0 | K | peptide | null | microtubule-associated protein tau | IMMUNE SYSTEM | 07/06/18 | FAB CBTAU-22.1 IN COMPLEX WITH TAU PEPTIDE V1088-5 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Juraszek, J., Steinbacher, S. | 2.63 | X-RAY DIFFRACTION | 0.270 | 0.216 | false | true | IGHV1 | IGKV2 | Kappa | 0.000006 | -7.164753 | Unknown | null | TBD |
7o85 | null | K | 0 | J | L | protein | protein | NA | NA | protective antigen pa-63 | fab | TOXIN | 04/14/21 | Anthrax toxin prepore in complex with the neutralizing Fab cAb29 | BACILLUS ANTHRACIS; MUS MUSCULUS | null | mus musculus | bacillus anthracis | mus musculus | Hoelzgen, F., Zalk, R., Alcalay, R., Cohen-Schwartz, S., Garau, G., Shahar, A., Mazor, O., Frank, G.A. | 3.3 | ELECTRON MICROSCOPY | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
4xwo | W | X | 0 | T | protein | null | atpase get3 | HYDROLASE/TRANSPORT PROTEIN | 01/29/15 | Structure of Get3 bound to the transmembrane domain of Sec22 | HOMO SAPIENS, SYNTHETIC CONSTRUCT; SACCHAROMYCES CEREVISIAE (ATCC 204508 / S288C); SACCHAROMYCES CEREVISIAE | homo sapiens, synthetic construct | homo sapiens, synthetic construct | saccharomyces cerevisiae (atcc 204508 / s288c) | Mateja, A., Paduch, M., Chang, H.-Y., Szydlowska, A., Kossiakoff, A.A., Hegde, R.S., Keenan, R.J. | 2.75 | X-RAY DIFFRACTION | 0.247 | 0.196 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3d85 | B | A | 0 | C | protein | null | interleukin-23 subunit p19 | IMMUNE SYSTEM/CYTOKINE | 05/22/08 | Crystal structure of IL-23 in complex with neutralizing FAB | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Beyer, B.M., Ingram, R., Ramanathan, L., Reichert, P., Le, H., Madison, V. | 1.9 | X-RAY DIFFRACTION | 0.214 | 0.171 | false | false | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
1t3f | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 04/26/04 | THREE DIMENSIONAL STRUCTURE OF A HUMANIZED ANTI-IFN-GAMMA FAB (HuZAF) IN P21 21 21 SPACE GROUP | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bourne, P.C., Terzyan, S.S., Cloud, G., Landolfi, N.F., Vasquez, M., Edmundson, A.B. | 2.0 | X-RAY DIFFRACTION | 0.222 | 0.172 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
3cvh | H | L | 0 | A | C | protein | peptide | NA | NA | h-2 class i histocompatibility antigen, k-b alpha chain | ovalbumin | IMMUNE SYSTEM | 04/18/08 | How TCR-like antibody recognizes MHC-bound peptide | MUS MUSCULUS; GALLUS GALLUS | mus musculus | mus musculus | mus musculus | gallus gallus | Mareeva, T., Martinez-Hackert, E., Sykulev, Y. | 2.9 | X-RAY DIFFRACTION | 0.296 | 0.219 | false | false | IGHV1 | IGKV13 | Kappa | null | null | null | null | null |
7m8l | O | R | 0 | F | protein | null | virion spike glycoprotein 2 | VIRAL PROTEIN/IMMUNE SYSTEM | 03/30/21 | EBOV GP bound to rEBOV-442 and rEBOV-515 Fabs | EBOLA VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | ebola virus | Murin, C.D., Ward, A.B. | 3.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
7wk8 | C | D | 0 | A | B | protein | peptide | NA | NA | spike glycoprotein | spike glycoprotein | VIRAL PROTEIN | 01/08/22 | SARS-CoV-2 Omicron spike protein SD1 in complex with S3H3 Fab | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; MUS MUSCULUS | mus musculus | mus musculus | severe acute respiratory syndrome coronavirus2 | severe acute respiratory syndrome coronavirus2 | Hong, Q., Cong, Y. | 3.61 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6bah | B | A | 0 | C | E | protein | protein | NA | NA | immunoglobulin g binding protein a | protein l | IMMUNE SYSTEM | 10/12/17 | Trastuzumab Fab v3 with 5-diphenyl meditope variant | MUS MUSCULUS; HOMO SAPIENS; FINEGOLDIA MAGNA; STAPHYLOCOCCUS AUREUS; SYNTHETIC CONSTRUCT | mus musculus, homo sapiens | mus musculus, homo sapiens | staphylococcus aureus | finegoldia magna | Bzymek, K.P., King, J.D., Williams, J.C. | 1.9 | X-RAY DIFFRACTION | 0.194 | 0.164 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4z8f | H | L | 0 | E | A | nucleic-acid | nucleic-acid | NA | NA | 5'-d(p*tp*tp*tp*tp*t)-3' | 5'-d(p*tp*tp*tp*tp*t)-3' | IMMUNE SYSTEM/DNA | 04/08/15 | Fab structure of antibody S1-15 in complex with ssDNA DNA, 5'-p5(dT)p-3' | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | | | Haji-Ghassemi, O., Evans, S.V. | 1.75 | X-RAY DIFFRACTION | 0.240 | 0.208 | false | false | IGHV10 | IGKV10 | Kappa | null | null | null | null | null |
5x4g | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 02/13/17 | Crystal structure of Fab fragment of anti-CD147 monoclonal antibody 6H8 | MUS MUSCULUS | mus musculus | mus musculus | null | Lin, P., Zhang, M.-Y., Chen, X., Ye, S., Yu, X.-L., Zhang, R.-G., Zhu, P., Chen, Z.-N. | 1.45 | X-RAY DIFFRACTION | 0.226 | 0.206 | false | true | IGHV6 | IGKV6 | Kappa | null | null | null | null | null |
5c3l | D | null | 0 | C | A | B | protein | protein | protein | NA | NA | NA | nucleoporin nup62 | nup54 | nucleoporin nup58 | TRANSPORT PROTEIN | 06/17/15 | Structure of the metazoan Nup62.Nup58.Nup54 nucleoporin complex. | XENOPUS LAEVIS; CAMELUS DROMEDARIUS | camelus dromedarius | null | xenopus laevis | xenopus laevis | xenopus laevis | Chug, H., Trakhanov, S., Hulsmann, B.B., Pleiner, T., Gorlich, D. | 2.9 | X-RAY DIFFRACTION | 0.301 | 0.265 | false | true | IGHV3 | null | null | null | null | null | null | null |
6lfx | A | a | 0 | a | Hapten | OM4 | 1,2-bis(chloranyl)-4-(3-chloranyl-4-methoxy-phenyl)benzene | IMMUNE SYSTEM | 12/03/19 | Crystal structure of PCB4scFv(hN56D) in complex with PCB#77 | MUS MUSCULUS | mus musculus | null | null | Nakamura, T., Yamagata, Y., Morioka, H. | 1.43 | X-RAY DIFFRACTION | 0.166 | 0.136 | true | true | unknown | unknown | unknown | null | null | null | null | null |
5jof | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 05/02/16 | Crystal structure of VRC03 gHVgLV antigen-binding fragment. | HOMO SAPIENS | homo sapiens | homo sapiens | null | Joyce, M.G., Mascola, J.R., Kwong, P.D. | 3.208 | X-RAY DIFFRACTION | 0.242 | 0.195 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6mej | H | L | 0 | C | protein | null | e2 glycoprotein | IMMUNE SYSTEM | 09/06/18 | Broadly neutralizing antibodies against HCV use a CDRH3 disulfide motif to recognize an E2 glycoprotein site that can be targeted for vaccine design | HOMO SAPIENS; HEPACIVIRUS C | homo sapiens | homo sapiens | hepacivirus c | Flyak, A.I., Bjorkman, P.J. | 2.8 | X-RAY DIFFRACTION | 0.271 | 0.198 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5wb2 | A | null | 0 | null | null | null | null | MEMBRANE PROTEIN | 06/27/17 | US28 bound to engineered chemokine CX3CL1.35 and nanobodies | HUMAN CYTOMEGALOVIRUS; LAMA GLAMA; HOMO SAPIENS; SYNTHETIC CONSTRUCT | human cytomegalovirus, lama glama | null | null | Jude, K.M., Burg, J.S., Tsutsumi, N., Miles, T.F., Garcia, K.C. | 3.5 | X-RAY DIFFRACTION | 0.296 | 0.252 | false | true | IGHV1 | null | null | null | null | null | null | null |
4xce | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 12/17/14 | Crystal structure of human 4E10 Fab crystalized in the presence of Phosphatidylcholine (06:0 PC); C2 space group | HOMO SAPIENS | homo sapiens | homo sapiens | null | Irimia, A., Stanfield, R.L., Wilson, I.A. | 2.93 | X-RAY DIFFRACTION | 0.247 | 0.192 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6hjx | G | null | 0 | B | protein | null | cys-loop ligand-gated ion channel | MEMBRANE PROTEIN | 09/04/18 | X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) 7'C pore mutant (L238C) in complex with nanobody 72 | DICKEYA CHRYSANTHEMI; LAMA GLAMA | lama glama | null | dickeya chrysanthemi | Spurny, R., Govaerts, C., Evans, G.L., Pardon, E., Steyaert, J., Ulens, C. | 2.5 | X-RAY DIFFRACTION | 0.245 | 0.204 | false | true | IGHV1 | null | null | null | null | null | null | null |
6ikm | O | o | 0 | null | null | null | null | ANTIMICROBIAL PROTEIN | 10/16/18 | Crystal structure of SpuE-Spermidine in complex with ScFv5 | PSEUDOMONAS AERUGINOSA; HOMO SAPIENS | pseudomonas aeruginosa | homo sapiens | null | Wu, D., Sun, X. | 3.398 | X-RAY DIFFRACTION | 0.268 | 0.228 | true | true | unknown | unknown | unknown | null | null | null | null | null |
7b27 | D | null | 0 | a | protein | null | unknown | VIRAL PROTEIN | 11/26/20 | RBD domain SARS-CoV2 in complex with neutralizing nanobody NM1230 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; VICUGNA PACOS | null | null | null | Ostertag, E., Zocher, G., Stehle, T. | 2.902 | X-RAY DIFFRACTION | 0.305 | 0.266 | false | false | unknown | unknown | unknown | null | null | null | null | null |
6my5 | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 11/01/18 | Crystal structure of the dimeric bH1-Fab variant [HC-Y33W,HC-D98F,HC-G99M,LC-S30bR] | HOMO SAPIENS | homo sapiens | homo sapiens | null | Shi, R. | 1.73 | X-RAY DIFFRACTION | 0.229 | 0.186 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5dhy | H | L | 0 | M | protein | null | protein rev | IMMUNE SYSTEM | 08/31/15 | HIV-1 Rev NTD dimers with variable crossing angles | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | DiMattia, M.A., Watts, N.R., Wingfield, P.T., Grimes, J.M., Stuart, D.I., Steven, A.C. | 3.1 | X-RAY DIFFRACTION | 0.300 | 0.291 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
1j05 | B | A | 0 | null | null | null | null | Immune system | 11/01/02 | The crystal structure of anti-carcinoembryonic antigen monoclonal antibody T84.66 Fv fragment | MUS MUSCULUS | mus musculus | mus musculus | null | Kondo, H., Nishimura, Y., Shiroishi, M., Asano, R., Noro, N., Tsumoto, K., Kumagai, I. | 1.5 | X-RAY DIFFRACTION | unknown | unknown | false | true | IGHV14 | IGKV3 | Kappa | null | null | null | null | null |
5j3h | C | D | 0 | E | protein | null | insulin receptor | HORMONE RECEPTOR/IMMUNE SYSTEM | 03/30/16 | Human insulin receptor domains L1-CR in complex with peptide S519C16 and 83-7 Fv | HOMO SAPIENS; MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Lawrence, M., Menting, J., Lawrence, C. | 3.27 | X-RAY DIFFRACTION | 0.248 | 0.226 | false | true | IGHV2 | IGKV8 | Kappa | 0 | -11.735309 | ITC | null | TBD |
2v7n | F | E | 0 | null | null | null | null | IMMUNE SYSTEM | 07/31/07 | Unusual twinning in crystals of the CitS binding antibody Fab fragment f3p4 | SYNTHETIC CONSTRUCT | synthetic construct | synthetic construct | null | Frey, D., Huber, T., Plueckthun, A., Gruetter, M.G. | 1.92 | X-RAY DIFFRACTION | unknown | unknown | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
6udk | O | P | 0 | R | protein | null | rc1 variant of hiv-1 env glycoprotein gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 09/19/19 | HIV-1 bNAb 1-55 in complex with modified BG505 SOSIP-based immunogen RC1 and 10-1074 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Abernathy, M.E., Barnes, C.O., Gristick, H.B., Bjorkman, P.J. | 3.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | unknown | unknown | null | null | null | null | null |
3chn | C | O | 0 | null | null | null | null | IMMUNE SYSTEM | 03/10/08 | Solution structure of human secretory IgA1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Almogren, A., Furtado, P.B., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING / HOMOLOGY MODEL | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7whk | F | null | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN | 12/30/21 | The state 3 complex structure of Omicron spike with Bn03 (2-up RBD, 5 nanobodies) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | null | severe acute respiratory syndrome coronavirus2 | Zhan, W.Q., Zhang, X., Chen, Z.G., Sun, L. | 3.01 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
5etu | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 11/18/15 | Cetuximab Fab in complex with L5E meditope variant | MUS MUSCULUS, HOMO SAPIENS; SYNTHETIC CONSTRUCT | mus musculus, homo sapiens | mus musculus, homo sapiens | null | Bzymek, K.P., Williams, J.C. | 2.53 | X-RAY DIFFRACTION | 0.232 | 0.180 | false | true | IGHV2 | IGKV5 | Kappa | 0.00013 | -5.30153 | Unknown | null | TBD |
2vxt | H | L | 0 | I | protein | null | interleukin-18 | CYTOKINE | 07/10/08 | Crystal structure of human IL-18 complexed to murine reference antibody 125-2H Fab | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Argiriadi, M.A., Xiang, T., Wu, C., Ghayur, T., Borhani, D.W. | 1.49 | X-RAY DIFFRACTION | 0.196 | 0.162 | false | true | IGHV1 | IGKV9 | Kappa | 0 | -12.64 | SPR | null | 19553661 |
6q0e | H | L | 0 | A | protein | null | hemagglutinin | IMMUNE SYSTEM | 08/01/19 | Inferred precursor (UCA) of the human antibody lineage 652 in complex with influenza hemagglutinin head domain of A/Beijing/262/95(H1N1) | INFLUENZA A VIRUS (A/BEIJING/262/1995(H1N1)); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus (a/beijing/262/1995(h1n1)) | McCarthy, K.R., Harrison, S.C. | 2.15 | X-RAY DIFFRACTION | 0.249 | 0.230 | false | true | IGHV4 | IGLV3 | Lambda | null | null | null | null | null |
6mb3 | G | Q | 0 | E | protein | null | plasmodium falciparum recombinant shortened csp | IMMUNE SYSTEM | 08/29/18 | Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts | PLASMODIUM FALCIPARUM; HOMO SAPIENS | homo sapiens | homo sapiens | plasmodium falciparum | Cottrell, C.A., Torres, J.L., Ward, A.B. | 3.37 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
6sne | D | C | 0 | J | peptide | null | envelope glycoprotein gp160 | IMMUNE SYSTEM | 08/23/19 | crystal structure of LN01 Fab in complex with an HIV-1 gp41 peptide | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Caillat, C., Pinto, D., Corti, D., Fenwick, C., Pantaleo, G., Weissenhorn, W. | 3.9 | X-RAY DIFFRACTION | 0.261 | 0.218 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
4mxw | W | V | 0 | X | protein | null | lymphotoxin-alpha | CYTOKINE/IMMUNE SYSTEM | 09/26/13 | Structure of heterotrimeric lymphotoxin LTa1b2 bound to lymphotoxin beta receptor LTbR and anti-LTa Fab | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Sudhamsu, J., Yin, J.P., Hymowitz, S.G. | 3.6 | X-RAY DIFFRACTION | 0.296 | 0.231 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5m95 | B | null | 0 | A | protein | null | divalent metal cation transporter mnth | TRANSPORT PROTEIN | 10/31/16 | STAPHYLOCOCCUS CAPITIS DIVALENT METAL ION TRANSPORTER (DMT) IN COMPLEX WITH MANGANESE | LAMA GLAMA; STAPHYLOCOCCUS CAPITIS | lama glama | null | staphylococcus capitis | Ehrnstorfer, I.A., Geertsma, E.R., Pardon, E., Steyaert, J., Dutzler, R. | 3.4 | X-RAY DIFFRACTION | 0.292 | 0.252 | false | true | IGHV1 | null | null | null | null | null | null | null |
5ir1 | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 03/11/16 | Cetuximab Fab in complex with 3-bromophenylalanine meditope variant | MUS MUSCULUS, HOMO SAPIENS; SYNTHETIC CONSTRUCT | mus musculus, homo sapiens | mus musculus, homo sapiens | null | Bzymek, K.P., Williams, J.C. | 2.482 | X-RAY DIFFRACTION | 0.215 | 0.163 | false | true | IGHV2 | IGKV5 | Kappa | null | null | null | null | null |
7me7 | A | null | 0 | R | protein | null | spike protein s1 | VIRAL PROTEIN/Immune System | 04/06/21 | CryoEM structure of SARS-CoV-2 RBD in complex with nanobodies Nb17 and Nb105 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; LAMA GLAMA | lama glama | null | severe acute respiratory syndrome coronavirus2 | Huang, W., Taylor, D.J. | 3.73 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
2iqa | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 10/13/06 | PFA2 FAB fragment, monoclinic apo form | MUS MUSCULUS | mus musculus | mus musculus | null | Gardberg, A.S., Dealwis, C. | 2.0 | X-RAY DIFFRACTION | 0.279 | 0.230 | false | false | IGHV8 | IGKV1 | Kappa | null | null | null | null | null |
6b3j | N | null | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | SIGNALING PROTEIN | 09/22/17 | 3.3 angstrom phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex | HOMO SAPIENS; LAMA GLAMA; SYNTHETIC CONSTRUCT | lama glama | null | homo sapiens | homo sapiens | Liang, Y.L., Khoshouei, M., Glukhova, A., Furness, S.G.B., Koole, C., Zhao, P., Clydesdale, L., Thal, D.M., Radjainia, M., Danev, R., Baumeister, W., Wang, M.W., Miller, L.J., Christopoulos, A., Sexton, P.M., Wootten, D. | 3.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
1rul | H | L | 0 | null | null | null | null | immune system | 12/11/03 | Crystal Structure (D) of u.v.-irradiated cationic cyclization antibody 4C6 Fab at pH 5.6 with a data set collected at SSRL beamline 11-1. | MUS MUSCULUS | mus musculus | mus musculus | null | Zhu, X., Wentworth Jr., P., Wentworth, A.D., Eschenmoser, A., Lerner, R.A., Wilson, I.A. | 1.88 | X-RAY DIFFRACTION | unknown | unknown | false | false | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5c9k | null | H | 0 | null | null | null | null | IMMUNE SYSTEM | 06/27/15 | Crystal structure of a highly fibrillogenic Arg24Gly mutant of the Recombinant variable domain 6AJL2 | HOMO SAPIENS | null | homo sapiens | null | Hernandez-Santoyo, A., Rodriguez-Romero, A., Luna-Martinez, O.D., Becerril-Lujan, B. | 1.92 | X-RAY DIFFRACTION | 0.219 | 0.170 | false | true | null | IGLV6 | Lambda | null | null | null | null | null |
6ch9 | D | E | 0 | B | protein | null | envelope glycoprotein gp41 | IMMUNE SYSTEM | 02/22/18 | Crystal structure of a natively-glycosylated B41 SOSIP.664 HIV-1 Envelope Trimer in complex with the broadly-neutralizing antibodies BG18 and 35O22 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Barnes, C.O., Bjorkman, P.J. | 4.85 | X-RAY DIFFRACTION | 0.292 | 0.285 | false | true | unknown | unknown | unknown | null | null | null | null | null |
5tru | H | L | 0 | C | protein | null | cytotoxic t-lymphocyte protein 4 | IMMUNE SYSTEM | 10/27/16 | Structure of the first-in-class checkpoint inhibitor Ipilimumab bound to human CTLA-4 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Ramagopal, U.A., Liu, W., Garrett-Thomson, S.C., Yan, Q., Srinivasan, M., Wong, S.C., Bell, A., Mankikar, S., Rangan, V.S., Deshpande, S., Bonanno, J.B., Korman, A.J., Almo, S.C. | 3.0 | X-RAY DIFFRACTION | 0.268 | 0.204 | false | true | IGHV3 | IGKV3 | Kappa | 0 | -10.879429 | Unknown | null | TBD |
5kan | H | L | 0 | B | C | protein | protein | NA | NA | hemagglutinin ha2 | hemagglutinin ha1 | IMMUNE SYSTEM | 06/01/16 | Crystal structure of multidonor HV1-18-class broadly neutralizing Influenza A antibody 16.g.07 in complex with A/Hong Kong/1-4-MA21-1/1968 (H3N2) Hemagglutinin | INFLUENZA A VIRUS (STRAIN A/HONG KONG/1/1968 H3N2); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus (strain a/hong kong/1/1968h3n2) | influenza a virus (strain a/hong kong/1/1968h3n2) | Joyce, M.G., Thomas, P.V., Wheatley, A.K., McDermott, A.B., Mascola, J.R., Kwong, P.D. | 2.785 | X-RAY DIFFRACTION | 0.243 | 0.218 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5zmj | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 04/04/18 | Crystal structure of the Fab region of a neutralizing fully human antibody against GM-CSF | HOMO SAPIENS | homo sapiens | homo sapiens | null | Angkawidjaja, C., Torashima, T. | 1.81 | X-RAY DIFFRACTION | 0.191 | 0.161 | false | true | IGHV7 | IGLV1 | Lambda | null | null | null | null | null |
3cfb | H | L | 0 | L | Hapten | SPB | 4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID | IMMUNE SYSTEM | 03/03/08 | High-resolution structure of blue fluorescent antibody EP2-19G2 in complex with stilbene hapten at 100K | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Debler, E.W., Wilson, I.A. | 1.6 | X-RAY DIFFRACTION | 0.218 | 0.186 | false | false | IGHV5 | IGKV2 | Kappa | null | null | null | null | null |
4nkm | G | H | 0 | null | null | null | null | IMMUNE SYSTEM/CHAPERONE | 11/12/13 | Crystal structure of engineered anti-EE scFv antibody fragment | MUS MUSCULUS | mus musculus | mus musculus | null | Kalyoncu, S., Hyun, J., Pai, J.C., Johnson, J.L., Etzminger, K., Jain, A., Heaner Jr., D., Molares, I.A., Truskett, T.M., Maynard, J.A., Lieberman, R.L. | 3.71 | X-RAY DIFFRACTION | 0.282 | 0.264 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7joz | N | null | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 08/07/20 | Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist | HOMO SAPIENS; LAMA GLAMA; ENTEROBACTERIA PHAGE T4 | lama glama | null | homo sapiens | homo sapiens | Sun, B., Feng, D., Chu, M.L., Fish, I., Kelm, S., Lebon, F., Lovera, S., Valade, A., Wood, M., Ceska, T., Kobilka, T.S., Sands, Z., Kobilka, B.K. | 3.8 | X-RAY DIFFRACTION | 0.297 | 0.254 | false | true | IGHV3 | null | null | null | null | null | null | null |
6h1f | A | null | 0 | B | protein | null | gelsolin | STRUCTURAL PROTEIN | 07/11/18 | Structure of the nanobody-stabilized gelsolin D187N variant (second domain) | LAMA GLAMA; HOMO SAPIENS | lama glama | null | homo sapiens | Hassan, A., Milani, M., Mastrangelo, E., de Rosa, M. | 1.9 | X-RAY DIFFRACTION | 0.233 | 0.199 | false | true | IGHV1 | null | null | null | null | null | null | null |
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