pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
6axp | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 09/07/17 | Structure of cetuximab with aminoheptanoic acid-linked n-octylarginine meditope variant | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | null | Bzymek, K.P., Williams, J.C. | 2.484 | X-RAY DIFFRACTION | 0.228 | 0.179 | false | true | IGHV2 | IGKV5 | Kappa | 0.000009 | -6.91751 | Unknown | null | TBD |
7czq | J | N | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN | 09/09/20 | S protein of SARS-CoV-2 in complex bound with P2B-1A10 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Yan, R.H., Zhang, Y.Y., Li, Y.N., Zhou, Q. | 2.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4k3d | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 04/10/13 | Crystal structure of bovine antibody BLV1H12 with ultralong CDR H3 | BOS TAURUS | bos taurus | bos taurus | null | Ekiert, D.C., Wang, F., Wilson, I.A. | 1.85 | X-RAY DIFFRACTION | 0.210 | 0.182 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7ws5 | E | D | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 01/28/22 | Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Guo, H., Gao, Y., Ji, X., Yang, H. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5a7x | R | Q | 0 | I | protein | null | hiv-1 yu2 gp120 | VIRAL PROTEIN | 07/10/15 | negative stain EM of BG505 SOSIP.664 in complex with sCD4, 17b, and 8ANC195 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Scharf, L., Wang, H., Gao, H., Chen, S., McDowall, A., Bjorkman, P. | 17.0 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
2qtj | D | N | 2 | null | null | null | null | IMMUNE SYSTEM | 08/02/07 | Solution structure of human dimeric immunoglobulin A | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Furtado, P.B., Almogren, A., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
4bel | D | null | 0 | A | protein | null | beta-secretase 2 | HYDROLASE/IMMUNE SYSTEM | 03/11/13 | BACE2 XAPERONE COMPLEX | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Banner, D.W., Kuglstatter, A., Benz, J., Stihle, M., Ruf, A. | 1.85 | X-RAY DIFFRACTION | 0.22234 | 0.18130 | false | true | IGHV3 | null | null | null | null | null | null | null |
7f62 | H | L | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN | 06/24/21 | Cryo-EM structure of SARS-CoV-2 spike in complex with a neutralizing antibody chAb-25 (Focused refinement of S-RBD and chAb-25 region) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Yang, T.J., Yu, P.Y., Wu, H.C., Hsu, S.T.D. | 3.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
7bxv | H | L | 0 | A | peptide | null | tyr-glu-val-his-his | IMMUNE SYSTEM | 04/21/20 | 11A1 antibody-peptide complex | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Irie, K., Irie, Y., Kita, A., Miki, K. | 1.75 | X-RAY DIFFRACTION | 0.194 | 0.166 | false | false | IGHV9 | IGKV1 | Kappa | null | null | null | null | null |
6xw7 | D | null | 0 | B | protein | null | capsid protein | VIRAL PROTEIN | 01/23/20 | Crystal structure of murine norovirus P domain in complex with Nanobody NB-5829 and glycochenodeoxycholate (GCDCA) | MURINE NOROVIRUS 1; VICUGNA PACOS | vicugna pacos | null | murine norovirus 1 | Kilic, T., Sabin, C., Hansman, G. | 2.15 | X-RAY DIFFRACTION | 0.215 | 0.171 | false | true | IGHV1 | null | null | null | null | null | null | null |
6mej | A | B | 0 | C | protein | null | e2 glycoprotein | IMMUNE SYSTEM | 09/06/18 | Broadly neutralizing antibodies against HCV use a CDRH3 disulfide motif to recognize an E2 glycoprotein site that can be targeted for vaccine design | HOMO SAPIENS; HEPACIVIRUS C | homo sapiens | homo sapiens | hepacivirus c | Flyak, A.I., Bjorkman, P.J. | 2.8 | X-RAY DIFFRACTION | 0.271 | 0.198 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
2oz4 | H | L | 0 | A | protein | null | intercellular adhesion molecule 1 | CELL ADHESION | 02/23/07 | Structural Plasticity in IgSF Domain 4 of ICAM-1 Mediates Cell Surface Dimerization | HOMO SAPIENS; MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Chen, X., Kim, T.D., Carman, C.V., Mi, L., Song, G., Springer, T.A. | 2.7 | X-RAY DIFFRACTION | 0.253 | 0.204 | false | false | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
6fuz | N | null | 0 | A | protein | null | kinesin light chain 1,kinesin light chain 1,c-jun-amino-terminal kinase-interacting protein 1 | MOTOR PROTEIN | 02/28/18 | Crystal structure of the TPR domain of KLC1 in complex with the C-terminal peptide of JIP1 | MUS MUSCULUS; HOMO SAPIENS; LAMA | lama | null | mus musculus, homo sapiens | Pernigo, S., Dodding, M.P., Steiner, R.A. | 2.7 | X-RAY DIFFRACTION | 0.257 | 0.233 | false | true | IGHV3 | null | null | null | null | null | null | null |
7zfe | Z | null | 0 | E | protein | null | spike protein s1 | VIRAL PROTEIN | 04/01/22 | SARS-CoV-2 Omicron RBD in complex with Omi-32 Fab and nanobody C1 | LAMA GLAMA; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | lama glama | null | severe acute respiratory syndrome coronavirus2 | Zhou, D., Huo, J., Ren, J., Stuart, D.I. | 3.25 | X-RAY DIFFRACTION | 0.293 | 0.237 | false | true | IGHV1 | null | null | null | null | null | null | null |
3nab | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 06/01/10 | Crystal Structure of fab15 Mut6 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Luo, J. | 2.32 | X-RAY DIFFRACTION | 0.259 | 0.203 | false | true | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
6oro | H | L | 0 | G | protein | null | rc1 variant of hiv-1 env glycoprotein gp120 | VIRAL PROTEIN/Immune System | 04/30/19 | Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab874NHP | HUMAN IMMUNODEFICIENCY VIRUS 1; MACACA MULATTA | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | Abernathy, M.E., Gristick, H.B., Bjorkman, P.J. | 3.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
5dd0 | H | L | 0 | P | peptide | null | oligo peptide | IMMUNE SYSTEM | 08/24/15 | Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques | HUMAN IMMUNODEFICIENCY VIRUS 1; MACACA MULATTA | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | Zhang, R., Verkoczy, L., Wiehe, K., Alam, S.M., Nicely, N.I., Santra, S., Bradley, T., Pemble, C., Gao, F., Montefiori, D.C., Bouton-Verville, H., Kelsoe, G., Parks, R., Foulger, A., Tomaras, G., Keple, T.B., Moody, M.A., Liao, H.-X., Haynes, B.F. | 2.488 | X-RAY DIFFRACTION | 0.274 | 0.227 | false | true | IGHV4 | IGKV1 | Kappa | 0 | -9.65513 | Unknown | null | TBD |
6h02 | B | null | 0 | A | protein | null | mediator of rna polymerase ii transcription subunit 23 | TRANSCRIPTION | 07/06/18 | Crystal structure of human Mediator subunit MED23 | HOMO SAPIENS; LAMA | lama | null | homo sapiens | Clantin, B., Monte, D., Villeret, V. | 2.8 | X-RAY DIFFRACTION | 0.240 | 0.199 | false | true | IGHV1 | null | null | null | null | null | null | null |
7mrz | X | Y | 0 | C | protein | null | activin receptor type-2b,activin receptor type-1b | SIGNALING PROTEIN/IMMUNE SYSTEM | 05/10/21 | Structure of GDF11 bound to fused ActRIIB-ECD and Alk4-ECD with Anti-ActRIIB Fab fragment | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Goebel, E.J., Kattamuri, C., Gipson, G.R., Thompson, T.B. | 3.0 | X-RAY DIFFRACTION | 0.327 | 0.288 | false | true | IGHV4 | IGKV4 | Kappa | null | null | null | null | null |
6cue | q | r | 0 | c | protein | null | unknown | VIRAL PROTEIN | 03/26/18 | Cryo-EM structure at 4.0 A resolution of vaccine-elicited antibody vFP7.04 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122 | HUMAN IMMUNODEFICIENCY VIRUS 1; MUS MUSCULUS; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Carragher, B., Potter, C.S., Kwong, P.D. | 4.0 | ELECTRON MICROSCOPY | null | null | false | false | unknown | unknown | unknown | null | null | null | null | null |
5aaw | F | f | 0 | G | protein | null | dengue serotype 4 envelope protein domain 3 | null | 07/30/15 | Structure of a redesigned cross-reactive antibody to dengue virus with increased in vivo potency | DENGUE VIRUS; MUS MUSCULUS | mus musculus | null | dengue virus | Wong, Y., Robinson, L., Lescar, J., Sasisekharan, R. | 3.27 | X-RAY DIFFRACTION | 0.26258 | 0.22661 | true | true | unknown | unknown | unknown | 0 | -11.411242 | SPR | null | TBD |
4r7d | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 08/27/14 | Fab Hu 15C1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Loyau, J., Didelot, G., Malinge, P., Ravn, U., Magistrelli, G., Depoisier, J.F., Kosco-Vilbois, M., Fischer, N., Thore, S., Rousseau, F. | 2.753 | X-RAY DIFFRACTION | 0.209 | 0.177 | false | true | IGHV4 | IGKV6 | Kappa | null | null | null | null | null |
7ezm | H | h | 0 | A | B | protein | protein | NA | NA | fusion protein of guanine nucleotide-binding protein g(i)subunit alpha-1 and guanine nucleotide-binding protein g(q) subunit alpha-q | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 06/01/21 | Cryo-EM structure of an activated Cholecystokinin A receptor (CCKAR)-Gq complex | HOMO SAPIENS; SYNTHETIC CONSTRUCT | synthetic construct | null | homo sapiens | homo sapiens | Liu, Q.F., Yang, D.H., Zhuang, Y.W., Croll, T.I., Cai, X.Q., Duan, J., Dai, A.T., Yin, W.C., Ye, C.Y., Zhou, F.L., Wu, B.L., Zhao, Q., Xu, H.E., Wang, M.W., Jiang, Y. | 2.9 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
3p9w | B | null | 0 | A | protein | null | vascular endothelial growth factor a | SIGNALING PROTEIN/IMMUNE SYSTEM | 10/18/10 | Crystal structure of an engineered human autonomous VH Domain in complex with VEGF | HOMO SAPIENS | homo sapiens | null | homo sapiens | Ma, X., Wiesmann, C. | 2.41 | X-RAY DIFFRACTION | 0.233 | 0.193 | false | true | IGHV3 | null | null | 0 | -10.635483 | SPR | null | TBD |
4xgz | M | N | 0 | m | peptide | null | unknown | CELL ADHESION | 01/04/15 | Crystal structure of human paxillin LD2 motif in complex with Fab fragment | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Nocula-Lugowska, M., Lugowski, M., Salgia, R., Kossiakoff, A.A. | 2.5 | X-RAY DIFFRACTION | 0.245 | 0.228 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -10.395252 | Unknown | null | TBD |
6ii9 | H | L | 0 | A | protein | null | hemagglutinin | IMMUNE SYSTEM | 10/03/18 | Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a human neutralizing antibody L3A-44 | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus | Jiang, H.H., Shi, Y., Qi, J., Gao, G.F. | 3.5 | X-RAY DIFFRACTION | 0.234 | 0.201 | false | true | IGHV4 | IGLV1 | Lambda | 0 | -10.521321 | SPR | null | TBD |
4jo2 | H | L | 0 | P | peptide | null | gp120 | IMMUNE SYSTEM/VIRAL PROTEIN | 03/16/13 | Crystal structure of rabbit mAb R56 Fab in complex with V3 crown of HIV-1 Consensus A gp120 | ORYCTOLAGUS CUNICULUS; HUMAN IMMUNODEFICIENCY VIRUS 1 | oryctolagus cuniculus | oryctolagus cuniculus | human immunodeficiency virus 1 | Pan, R.M., Kong, X.P. | 2.5 | X-RAY DIFFRACTION | 0.265 | 0.190 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6wtv | E | F | 0 | D | protein | null | reticulocyte binding protein 2b | CELL INVASION | 05/04/20 | Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 258259 | PLASMODIUM VIVAX (STRAIN SALVADOR I); HOMO SAPIENS | homo sapiens | homo sapiens | plasmodium vivax (strain salvador i) | Chan, L.J., Dietrich, M.H., Tham, W.H. | 3.05 | X-RAY DIFFRACTION | 0.277 | 0.235 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
1l7t | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 03/17/02 | Crystal Structure Analysis of the anti-testosterone Fab fragment | MUS MUSCULUS | mus musculus | mus musculus | null | Valjakka, J., Hemminki, A., Niemi, S., Soderlund, H., Takkinen, K., Rouvinen, J. | 2.1 | X-RAY DIFFRACTION | 0.275 | 0.213 | false | true | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
7cai | E | D | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN | 06/08/20 | SARS-CoV-2 S trimer with two RBDs in the open state and complexed with two H014 Fab | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhe, L., Cao, L., Deng, Y., Sun, Y., Wang, N., Xie, L., Wang, Y., Rao, Z., Qin, C., Wang, X. | 3.49 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
5ihz | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 03/01/16 | Crystal structure of anti-gliadin 1002-1E01 Fab fragment | HOMO SAPIENS | homo sapiens | homo sapiens | null | Chen, X., Zhao, Y., Harlos, K., Snir, O., Sollid, L.M. | 1.64 | X-RAY DIFFRACTION | 0.229 | 0.200 | false | true | IGHV3 | IGLV4 | Lambda | null | null | null | null | null |
5wdu | U | V | 0 | R | protein | null | envelope glycoprotein gp160 | IMMUNE SYSTEM | 07/06/17 | HIV-1 Env BG505 SOSIP.664 H72C-H564C trimer in complex with bNAbs PGT122 Fab, 35O22 Fab and NIH45-46 scFv | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Julien, J.-P., Torrents de la Pena, A., Sanders, R.W., Wilson, I.A. | 7.0 | X-RAY DIFFRACTION | 0.363 | 0.301 | false | true | unknown | unknown | unknown | null | null | null | null | null |
5vjo | A | B | 0 | E | protein | null | lysozyme isoform i (del-i) | HYDROLASE/IMMUNE SYSTEM | 04/19/17 | Complex between HyHEL10 Fab fragment heavy chain mutant I29F and Pekin duck egg lysozyme isoform I (DEL-I) | MUS MUSCULUS; ANAS PLATYRHYNCHOS | mus musculus | mus musculus | anas platyrhynchos | Langley, D.B., Christ, D. | 2.43 | X-RAY DIFFRACTION | 0.296 | 0.262 | false | true | IGHV3 | IGKV5 | Kappa | null | null | null | null | null |
6hd8 | A | null | 0 | null | null | null | null | TRANSPORT PROTEIN | 08/17/18 | Crystal structure of the potassium channel MtTMEM175 in complex with a Nanobody-MBP fusion protein | LAMA GLAMA; ESCHERICHIA COLI (STRAIN K12); MARIVIRGA TRACTUOSA DSM 4126 | lama glama, escherichia coli (strain k12) | null | null | Brunner, J.D., Jakob, R.P., Schulze, T., Neldner, Y., Moroni, A., Thiel, G., Maier, T., Schenck, S. | 2.4 | X-RAY DIFFRACTION | 0.253 | 0.209 | false | true | IGHV1 | null | null | null | null | null | null | null |
6p9x | N | null | 0 | A | B | G | protein | protein | protein | NA | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | guanine nucleotide-binding protein g(i)/g(s)/g(o) subunitgamma-2 | MEMBRANE PROTEIN | 06/10/19 | CRF1 Receptor Gs GPCR protein complex with CRF1 peptide | HOMO SAPIENS; LAMA GLAMA; SYNTHETIC CONSTRUCT | lama glama | null | homo sapiens | homo sapiens | homo sapiens | Belousoff, M.J., Liang, Y.L., Sexton, P., Danev, R. | 2.91 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
5x2q | J | K | 0 | C | D | protein | protein | NA | NA | taste receptor, type 1, member 2a | taste receptor, type 1, member 3 | SIGNALING PROTEIN/IMMUNE SYSTEM | 02/02/17 | Crystal structure of the medaka fish taste receptor T1r2a-T1r3 ligand binding domains in complex with glycine | ORYZIAS LATIPES; MUS MUSCULUS | mus musculus | mus musculus | oryzias latipes | oryzias latipes | Nuemket, N., Yasui, N., Atsumi, N., Yamashita, A. | 2.6 | X-RAY DIFFRACTION | 0.230 | 0.154 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6cuf | 3 | 4 | 0 | A | protein | null | envelope glycoprotein gp41 | VIRAL PROTEIN | 03/26/18 | Cryo-EM structure at 4.2 A resolution of vaccine-elicited antibody vFP1.01 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122 | MUS MUSCULUS; HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | mus musculus | mus musculus | human immunodeficiency virus 1 | Acharya, P., Carragher, B., Potter, C.S., Kwong, P.D. | 4.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6y90 | H | L | 0 | A | protein | null | b-lymphocyte antigen cd20 | MEMBRANE PROTEIN | 03/06/20 | Structure of full-length CD20 in complex with Rituximab Fab | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Kumar, A., Reyes, N. | 3.69 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
1qnz | H | L | 0 | P | peptide | null | gp120 | IMMUNE SYSTEM | 10/26/99 | NMR structure of the 0.5b anti-HIV antibody complex with the gp120 V3 peptide | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | human immunodeficiency virus | Tugarinov, V., Zvi, A., Levy, R., Hayek, Y., Matsushita, S., Anglister, J. | NOT | SOLUTION NMR | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6aq7 | H | L | 0 | A | protein | null | major prion protein | IMMUNE SYSTEM | 08/18/17 | Structure of POM6 FAB fragment complexed with mouse PrPc | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Baral, P.K., Swayampakula, M., James, M.N.G. | 1.83 | X-RAY DIFFRACTION | 0.230 | 0.197 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
4lvo | C | B | 0 | A | protein | null | subtilisin-like serine protease | HYDROLASE/INHIBITOR/IMMUNE SYSTEM | 07/26/13 | Crystal structure of PfSUB1-prodomain-NIMP.M7 Fab complex with added CaCl2 | PLASMODIUM FALCIPARUM; MUS MUSCULUS | mus musculus | mus musculus | plasmodium falciparum | Withers-Martinez, C., Blackman, M.J. | 2.26 | X-RAY DIFFRACTION | 0.236 | 0.191 | false | false | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
5d9q | O | o | 0 | J | protein | null | envelope glycoprotein gp120 | IMMUNE SYSTEM | 08/18/15 | Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122 and scFv NIH45-46 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | null | human immunodeficiency virus 1 | Julien, J.-P., Stanfield, R.L., Ward, A.B., Wilson, I.A. | 4.4 | X-RAY DIFFRACTION | 0.320 | 0.290 | true | true | unknown | unknown | unknown | null | null | null | null | null |
4kvn | H | L | 0 | A | protein | null | hemagglutinin | IMMUNE SYSTEM | 05/22/13 | Crystal structure of Fab 39.29 in complex with Influenza Hemagglutinin A/Perth/16/2009 (H3N2) | HOMO SAPIENS; INFLUENZA A VIRUS | homo sapiens | homo sapiens | influenza a virus | Fong, R., Swem, L.R., Lupardus, P.J. | 3.1 | X-RAY DIFFRACTION | 0.248 | 0.202 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
7jhj | D | d | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(i) subunit alpha-1 | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 07/20/20 | Structure of the Epstein-Barr virus GPCR BILF1 in complex with human Gi | HOMO SAPIENS; MUS MUSCULUS; EPSTEIN-BARR VIRUS | mus musculus | null | homo sapiens | homo sapiens | Tsutsumi, N., Qu, Q.H., Skiniotis, G., Garcia, K.C. | 3.2 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
6nc2 | R | W | 0 | M | F | protein | protein | NA | NA | amc011 v4.2 sosip gp41 | amc011 v4.2 sosip gp120 | IMMUNE SYSTEM | 12/10/18 | AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody ACS202 fragment antigen binding | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | human immunodeficiency virus 1 | Cottrell, C.A., Ozorowski, G., Yuan, M., Copps, J., Wilson, I.A., Ward, A.B. | 5.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6ddm | B | A | 0 | C | protein | null | mhc class i polypeptide-related sequence a | IMMUNE SYSTEM | 05/10/18 | Crystal Structure Analysis of the Epitope of an Anti-MICA Antibody | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Matsumoto, M.L. | 1.3 | X-RAY DIFFRACTION | 0.205 | 0.188 | false | true | IGHV1 | IGKV4 | Kappa | 0 | -12.792177 | ITC | null | TBD |
7cah | E | D | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN | 06/08/20 | The interface of H014 Fab binds to SARS-CoV-2 S | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhe, L., Cao, L., Deng, Y., Sun, Y., Wang, N., Xie, L., Rao, Z., wang, Y., Qin, C., Wang, X. | 3.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
7su1 | H | L | 0 | C | protein | null | cytotoxic t-lymphocyte protein 4 | IMMUNE SYSTEM | 11/15/21 | Crystal structure of an acidic pH-selective Ipilimumab variant Ipi.106 in complex with CTLA-4 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Lee, P.S., Chau, B., Strop, P. | 2.53 | X-RAY DIFFRACTION | 0.251 | 0.206 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
2gk0 | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 03/31/06 | Structure of Catalytic Elimination Antibody 13G5 from a twinned crystal in space group C2 | MUS MUSCULUS | mus musculus | mus musculus | null | Debler, E.W., Wilson, I.A. | 2.45 | X-RAY DIFFRACTION | unknown | unknown | false | false | IGHV2 | IGKV1 | Kappa | null | null | null | null | null |
4ki5 | C | D | 0 | M | protein | null | coagulation factor viii | IMMUNE SYSTEM | 05/01/13 | Cystal structure of human factor VIII C2 domain in a ternary complex with murine inhbitory antibodies 3E6 and G99 | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Walter, J.D., Meeks, S.L., Healey, J.F., Lollar, P., Spiegel, P.C. | 2.47 | X-RAY DIFFRACTION | 0.238 | 0.188 | false | false | IGHV9 | IGKV4 | Kappa | null | null | null | null | null |
6vgr | H | L | 0 | B | protein | null | dipeptidase 3 | HYDROLASE | 05/13/20 | Crystal Structure of Human Dipeptidase 3 in Complex with Fab of SC-003 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Hayashi, K., Longenecker, K.L., Vivona, S. | 2.84 | X-RAY DIFFRACTION | 0.248 | 0.190 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6vca | H | L | 0 | B | protein | null | 5'-nucleotidase, ecto (cd73), isoform cra_a | IMMUNE SYSTEM | 12/20/19 | TB38 complex | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Zhou, Y.F., Lord, D.M. | 3.73 | X-RAY DIFFRACTION | 0.264 | 0.224 | false | true | IGHV3 | IGLV8 | Lambda | null | null | null | null | null |
5dk3 | G | F | 0 | null | null | null | null | IMMUNE SYSTEM | 09/02/15 | Crystal Structure of Pembrolizumab, a full length IgG4 antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Scapin, G., Prosise, W., Reichert, P. | 2.28 | X-RAY DIFFRACTION | 0.224 | 0.184 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5jw5 | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 05/11/16 | Structure of MEDI8852 Fab Fragment | HOMO SAPIENS | homo sapiens | homo sapiens | null | Neu, U., Collins, P.J., Walker, P.A., Vorlaender, M.K., Ogrodowicz, R.W., Martin, S.R., Gamblin, S.J., Skehel, J.J. | 1.9 | X-RAY DIFFRACTION | 0.217 | 0.187 | false | true | IGHV6 | IGKV1 | Kappa | null | null | null | null | null |
7dkj | K | L | 0 | I | protein | null | hemagglutinin | VIRAL PROTEIN | 11/24/20 | Hemagglutinin Influenza A virus (A/Okuda/1957(H2N2) bound with a neutralizing antibody | INFLUENZA A VIRUS (A/OKUDA/1957(H2N2)); MUS MUSCULUS | mus musculus | mus musculus | influenza a virus (a/okuda/1957(h2n2)) | Kamada, K., Shirouzu, M. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV7 | IGKV12 | Kappa | null | null | null | null | null |
7fab | H | L | 0 | null | null | null | null | IMMUNOGLOBULIN | 11/20/91 | CRYSTAL STRUCTURE OF HUMAN IMMUNOGLOBULIN FRAGMENT FAB NEW REFINED AT 2.0 ANGSTROMS RESOLUTION | HOMO SAPIENS | homo sapiens | homo sapiens | null | Saul, F., Poljak, R.J. | 2.0 | X-RAY DIFFRACTION | unknown | 0.169 | false | true | IGHV4 | IGLV1 | Lambda | null | null | null | null | null |
5ovw | K | null | 0 | E | protein | null | vitamin b12-binding protein | TRANSPORT PROTEIN | 08/30/17 | Nanobody-bound BtuF, the vitamin B12 binding protein in Escherichia coli | ESCHERICHIA COLI; LAMA GLAMA | lama glama | null | escherichia coli | Mireku, S.A., Sauer, M.M., Glockshuber, R., Locher, K.P. | 2.653 | X-RAY DIFFRACTION | 0.259 | 0.223 | false | true | IGHV1 | null | null | null | null | null | null | null |
2kh2 | B | b | 72 | A | protein | null | interleukin-1 beta | Cytokine/IMMUNE SYSTEM | 03/23/09 | Solution structure of a scFv-IL-1B complex | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | Wilkinson, I.C., Hall, C.J., Veverka, V., Muskett, F.W., Stephens, P.E., Taylor, R.J., Henry, A.J., Carr, M.D. | NOT | SOLUTION NMR | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
1fvd | D | C | 0 | null | null | null | null | IMMUNOGLOBULIN | 10/20/92 | X-RAY STRUCTURES OF THE ANTIGEN-BINDING DOMAINS FROM THREE VARIANTS OF HUMANIZED ANTI-P185-HER2 ANTIBODY 4D5 AND COMPARISON WITH MOLECULAR MODELING | HOMO SAPIENS | homo sapiens | homo sapiens | null | Eigenbrot, C., Presta, L., Randal, M., Kossiakoff, A.A. | 2.5 | X-RAY DIFFRACTION | unknown | 0.179 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6ey6 | J | null | 0 | B | protein | null | t9ss component cytoplasmic membrane protein porm | PROTEIN TRANSPORT | 11/10/17 | C-terminal part (residues 315-516) of PorM with the llama naobody nb130 | PORPHYROMONAS GINGIVALIS; LAMA GLAMA | lama glama | null | porphyromonas gingivalis | Leone, P., Cambillau, C., Roussel, A. | 2.1 | X-RAY DIFFRACTION | 0.215 | 0.181 | false | true | IGHV1 | null | null | null | null | null | null | null |
6fyw | C | null | 0 | A | B | protein | protein | NA | NA | hemagglutinin | hemagglutinin | VIRAL PROTEIN | 03/12/18 | Structure of B/Brisbane/60/2008 Influenza Hemagglutinin in complex with SD83 | INFLUENZA B VIRUS (B/BRISBANE/60/2008); LAMA GLAMA | lama glama | null | influenza b virus (b/brisbane/60/2008) | influenza b virus (b/brisbane/60/2008) | Laursen, N.S., Wilson, I.A. | 2.2 | X-RAY DIFFRACTION | 0.218 | 0.193 | false | true | IGHV1 | null | null | null | null | null | null | null |
6d01 | C | D | 0 | I | peptide | null | nanp5 | IMMUNE SYSTEM | 04/09/18 | Crystal structure of 1210 Fab in complex with circumsporozoite protein NANP5 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | plasmodium falciparum | Scally, S.W., Bosch, A., Imkeller, K., Wardemann, H., Julien, J.P. | 3.2 | X-RAY DIFFRACTION | 0.227 | 0.204 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -8.927114 | Unknown | null | TBD |
6dwa | B | A | 0 | B | carbohydrate | HD4 | 4-O-[2-acetamido-2-deoxy-beta-D-glucopyranosyl]-1-O-phosphono-D-ribitol | IMMUNE SYSTEM | 06/26/18 | Structure of the 4497 Antibody Fab fragment bound to a Staphylococcus aureus wall techoic acid analog | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Fong, R., Lupardus, P.J. | 1.922 | X-RAY DIFFRACTION | 0.235 | 0.207 | false | true | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
6xey | F | G | 0 | B | protein | null | sars-cov-2 spike glycoprotein | VIRAL PROTEIN/Immune System | 06/14/20 | Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-4 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Rapp, M., Shapiro, L., Ho, D.D. | 3.25 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV2 | Lambda | null | null | null | null | null |
6nf2 | H | L | 0 | B | protein | null | envelope glycoprotein gp41 | IMMUNE SYSTEM | 12/18/18 | Cryo-EM structure of vaccine-elicited antibody 0PV-c.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Gorman, J., Kwong, P.D. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGKV2 | Kappa | null | null | null | null | null |
4k8r | H | L | 0 | B | A | protein | protein | NA | NA | proprotein convertase subtilisin/kexin type 9 | proprotein convertase subtilisin/kexin type 9 | IMMUNE SYSTEM | 04/18/13 | An Antibody Against the C-terminal Domain of PCSK9 lowers LDL Cholesterol Levels in vivo | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | homo sapiens | Schiele, F., Nar, H. | 3.22 | X-RAY DIFFRACTION | 0.226 | 0.167 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
6wqo | E | F | 0 | D | protein | null | reticulocyte binding protein 2b | CELL INVASION | 04/29/20 | Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 283284 | PLASMODIUM VIVAX (STRAIN SALVADOR I); HOMO SAPIENS | homo sapiens | homo sapiens | plasmodium vivax (strain salvador i) | Chan, L.J., Dietrich, M.H., Tham, W.H. | 3.15 | X-RAY DIFFRACTION | 0.305 | 0.254 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
7web | H | L | 0 | B | protein | null | spike glycoprotein | IMMUNE SYSTEM/VIRAL PROTEIN | 12/23/21 | SARS-CoV-2 Omicron variant spike protein with two XGv347 binding to two open state RBDs | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Wang, X., Wang, L. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
3qpq | F | E | 0 | null | null | null | null | IMMUNE SYSTEM | 02/14/11 | Crystal structure of ANTI-TLR3 antibody C1068 FAB | HOMO SAPIENS, MUS MUSCULUS | homo sapiens, mus musculus | homo sapiens, mus musculus | null | Luo, J., Obmolova, G., Teplyakov, A., Gilliland, G.L. | 1.9 | X-RAY DIFFRACTION | 0.256 | 0.201 | false | true | IGHV1 | IGKV12 | Kappa | null | null | null | null | null |
5f72 | T | t | 0 | C | protein | null | kelch-like ech-associated protein 1 | DE NOVO PROTEIN | 12/07/15 | De novo design and crystallographic validation of antibodies targeting a pre-selected epitope | HOMO SAPIENS | homo sapiens | null | homo sapiens | Liu, X., Taylor, R.D., Griffin, L., Coker, S., Adams, R., Ceska, T., Shi, J., Lawson, A.D.G., Baker, T. | 1.85 | X-RAY DIFFRACTION | 0.265 | 0.223 | true | true | unknown | unknown | unknown | null | null | null | null | null |
6x87 | I | J | 0 | X | protein | null | circumsporozoite protein | IMMUNE SYSTEM | 06/01/20 | CryoEM structure of the Plasmodium berghei circumsporozoite protein in complex with inhibitory mouse antibody 3D11. | MUS MUSCULUS; PLASMODIUM BERGHEI | mus musculus | mus musculus | plasmodium berghei | Kucharska, I., Thai, E., Rubinstein, J., Julien, J.P. | 3.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5gjs | H | L | 0 | B | A | protein | protein | NA | NA | hemagglutinin | hemagglutinin | IMMUNE SYSTEM | 07/01/16 | Crystal structure of H1 hemagglutinin from A/California/04/2009 in complex with a neutralizing antibody 3E1 | HOMO SAPIENS; INFLUENZA A VIRUS | homo sapiens | homo sapiens | influenza a virus | influenza a virus | Wang, W., Zhang, T., Ding, J. | 2.9 | X-RAY DIFFRACTION | 0.304 | 0.251 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
4n9g | A | B | 0 | C | peptide | null | epitope scaffold rsv_1isea_ffl_001_c | IMMUNE SYSTEM | 10/21/13 | Crystal Structure of a Computationally Designed RSV-Presenting Epitope Scaffold And Its Elicited Antibody 17HD9 | MACACA MULATTA; SYNTHETIC CONSTRUCT | macaca mulatta | macaca mulatta | synthetic construct | Carrico, C.T.D., Strong, R.K. | 2.5 | X-RAY DIFFRACTION | 0.295 | 0.263 | false | true | IGHV4 | IGKV1 | Kappa | 0 | -12.942287 | Unknown | null | TBD |
6meg | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 09/06/18 | Broadly neutralizing antibodies against HCV use a CDRH3 disulfide motif to recognize an E2 glycoprotein site that can be targeted for vaccine design | HOMO SAPIENS | homo sapiens | homo sapiens | null | Flyak, A.I., Bjorkman, P.J. | 1.41 | X-RAY DIFFRACTION | 0.200 | 0.174 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
3u0t | B | A | 0 | F | peptide | null | amyloid beta a4 protein | IMMUNE SYSTEM | 09/29/11 | Fab-antibody complex | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | LaPorte, S.L., Pons, J.P. | 2.5 | X-RAY DIFFRACTION | 0.268 | 0.219 | false | true | IGHV1 | IGKV2D | Kappa | 0 | -12.991531 | Unknown | null | TBD |
1dfb | H | L | 0 | null | null | null | null | IMMUNOGLOBULIN | 03/27/92 | STRUCTURE OF A HUMAN MONOCLONAL ANTIBODY FAB FRAGMENT AGAINST GP41 OF HUMAN IMMUNODEFICIENCY VIRUS TYPE I | HOMO SAPIENS | homo sapiens | homo sapiens | null | He, X.M., Rueker, F., Casale, E., Carter, D.C. | 2.7 | X-RAY DIFFRACTION | unknown | 0.177 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6n1v | f | h | 0 | A | protein | null | pgt122 light chain | VIRAL PROTEIN | 11/12/18 | Cryo-EM structure at 4.0 A resolution of vaccine-elicited antibody A12V163-a.01 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122 | MACACA MULATTA; HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Kwong, P.D. | 4 | ELECTRON MICROSCOPY | null | null | false | false | unknown | unknown | unknown | null | null | null | null | null |
1igm | H | L | 0 | null | null | null | null | IMMUNOGLOBULIN | 07/10/92 | THREE DIMENSIONAL STRUCTURE OF AN FV FROM A HUMAN IGM IMMUNOGLOBULIN | HOMO SAPIENS | homo sapiens | homo sapiens | null | Fan, Z.-C., Guddat, L.W., Edmundson, A.B. | 2.3 | X-RAY DIFFRACTION | unknown | unknown | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6vmj | B | A | 0 | Z | protein | null | complement factor d | HYDROLASE/IMMUNE SYSTEM | 01/28/20 | Crystal structure of human Complement Factor D with anti-Factor D Fab 20D12 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Wu, P., Harris, S.F., Eigenbrot, C. | 2.95 | X-RAY DIFFRACTION | 0.265 | 0.218 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6wo5 | H | L | 0 | E | protein | null | envelope glycoprotein e2 | IMMUNE SYSTEM/Viral Protein | 04/24/20 | Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 1a bound to neutralizing antibody 212.1.1 and non neutralizing antibody E1 | HOMO SAPIENS; HEPATITIS C VIRUS (ISOLATE H) | homo sapiens | homo sapiens | hepatitis c virus (isolate h) | Tzarum, N., Wilson, I.A., Law, M. | 2.619 | X-RAY DIFFRACTION | 0.250 | 0.203 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6fys | F | null | 0 | null | null | null | null | VIRAL PROTEIN | 03/12/18 | Structure of single domain antibody SD83 | LAMA GLAMA | lama glama | null | null | Laursen, N.S., Wilson, I.A. | 2.0 | X-RAY DIFFRACTION | 0.231 | 0.201 | false | true | IGHV1 | null | null | null | null | null | null | null |
5zs0 | B | A | 0 | C | protein | null | envelope glycoprotein b,envelope glycoprotein b | VIRAL PROTEIN | 04/26/18 | Structure of glycoprotein B Domain IV of pseudorabies virus with 7B11 antibody | SUID ALPHAHERPESVIRUS 1; MUS MUSCULUS | mus musculus | mus musculus | suid alphaherpesvirus 1 | Hu, X.L., Yang, F.L. | 3.29 | X-RAY DIFFRACTION | 0.310 | 0.241 | false | false | IGHV5 | IGKV6 | Kappa | null | null | null | null | null |
4jm2 | A | B | 0 | E | protein | null | gp120 | IMMUNE SYSTEM/VIRAL PROTEIN | 03/13/13 | Crystal Structure of PGT 135 Fab in Complex with gp120 Core Protein from HIV-1 Strain JR-FL Bound to CD4 and 17b Fab | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Kong, L., Wilson, I.A. | 3.1 | X-RAY DIFFRACTION | 0.285 | 0.238 | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
3wih | H | L | 0 | A | protein | null | roundabout homolog 1 | IMMUNE SYSTEM | 09/12/13 | Crystal structure of the third fibronectin domain (Fn3) of human ROBO1 in complex with the Fab fragment of murine monoclonal antibody B2212A. | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Nakayama, T., Mizohata, E., Yamashita, T., Nagatoishi, M., Iwanari, H., Mochizuki, Y., Kado, Y., Yokota, Y., Sato, R., Tsumoto, K., Fujitani, H., Kodama, T., Hamakubo, T., Inoue, T. | 1.701 | X-RAY DIFFRACTION | 0.236 | 0.189 | false | false | IGHV1 | IGKV10 | Kappa | 0 | -10.533665 | ITC | null | TBD |
5t85 | H | L | 0 | G | protein | null | 10e8 epitope scaffold t117v2 | IMMUNE SYSTEM | 09/06/16 | Crystal structure of 10E8 Fab in complex with the MPER epitope scaffold T117v2 and phosphatidylglycerol (06:0 PG) | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | synthetic construct | Irimia, A., Wilson, I.A. | 2.373 | X-RAY DIFFRACTION | 0.250 | 0.195 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
5vkk | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 04/21/17 | Crystal structure of Fab fragment of anti-CD22 Epratuzumab | HOMO SAPIENS, MUS MUSCULUS; HOMO SAPIENS | homo sapiens, mus musculus, homo sapiens | homo sapiens, mus musculus, homo sapiens | null | Sicard, T., Ereno Orbea, J., Julien, J.-P. | 2.014 | X-RAY DIFFRACTION | 0.237 | 0.212 | false | true | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
1mhh | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 08/20/02 | Antibody-antigen complex | FINEGOLDIA MAGNA; MUS MUSCULUS | mus musculus | mus musculus | null | Graille, M., Stura, E.A. | 2.1 | X-RAY DIFFRACTION | 0.247 | 0.197 | false | false | IGHV9 | IGKV8 | Kappa | 0 | -12.278197 | Unknown | null | TBD |
7kqy | E | null | 0 | null | null | null | null | IMMUNE SYSTEM | 11/18/20 | Crystal Structure and Characterization of Human Heavy-Chain only Antibodies reveals a novel, stable dimeric structure similar to Monoclonal Antibodies | HOMO SAPIENS | homo sapiens | null | null | Bahmanjah, S., Mieczkowski, C., Yu, Y., Baker, J., Raghunathan, G., Tomazela, D., Hsieh, M., Mccoy, M., Strickland, C., Fayadat-Dilman, L. | 2.913 | X-RAY DIFFRACTION | 0.260 | 0.207 | false | true | IGHV1 | null | null | null | null | null | null | null |
4py7 | I | J | 0 | null | null | null | null | IMMUNE SYSTEM | 03/26/14 | Crystal Structure of Fab 3.1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Dreyfus, C. | 2.7 | X-RAY DIFFRACTION | 0.273 | 0.228 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7sl8 | B | null | 0 | A | protein | null | sodium/glucose cotransporter 1 | MEMBRANE PROTEIN | 10/23/21 | CryoEM structure of SGLT1 at 3.4 A resolution | HOMO SAPIENS; SYNTHETIC CONSTRUCT | synthetic construct | null | homo sapiens | Qu, Q., Han, L., Panova, O., Feng, L., Skiniotis, G. | 3.4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
3dgg | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 06/13/08 | Crystal structure of FabOX108 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Ren, J., Nettleship, J.E., Owens, R.J., Oxford Protein Production Facility (OPPF) | 2.3 | X-RAY DIFFRACTION | 0.246 | 0.187 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
5i75 | B | C | 0 | A | protein | null | sodium-dependent serotonin transporter | MEMBRANE PROTEIN | 02/16/16 | X-ray structure of the ts3 human serotonin transporter complexed with s-citalopram at the central site and Br-citalopram at the allosteric site | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Coleman, J.A., Green, E.M., Gouaux, E. | 3.49 | X-RAY DIFFRACTION | 0.286 | 0.244 | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
4ob5 | H | L | 0 | L | Hapten | TMO | TRIMETHYLAMINE OXIDE | IMMUNE SYSTEM | 01/06/14 | Ontogeny of recognition specificity and functionality for the broadly neutralizing anti-HIV antibody 4E10 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Jaffe, J.B., Rupert, P.B. | 1.7 | X-RAY DIFFRACTION | 0.207 | 0.178 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7fjo | J | K | 0 | B | protein | null | spike glycoprotein | IMMUNE SYSTEM/VIRAL PROTEIN | 08/04/21 | Cryo-EM structure of South African (B.1.351) SARS-CoV-2 spike glycoprotein in complex with three T6 Fab | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Wang, X., Zhang, L., Zhang, S., Liang, Q. | 3.34 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
4w2q | A | null | 0 | B | protein | null | nucleoprotein | IMMUNE SYSTEM | 08/17/17 | Anti-Marburgvirus Nucleoprotein Single Domain Antibody C Complexed with Nucleoprotein C-terminal domain | LAMA GLAMA; LAKE VICTORIA MARBURGVIRUS | lama glama | null | lake victoria marburgvirus | Taylor, A.B., Garza, J.A. | 2.7 | X-RAY DIFFRACTION | 0.274 | 0.220 | false | true | IGHV1 | null | null | null | null | null | null | null |
4ouu | B | A | 0 | null | null | null | null | HYDROLASE | 02/19/14 | anti-MT1-MMP monoclonal antibody | MUS MUSCULUS | mus musculus | mus musculus | null | Udi, Y., Grossman, M., Solomonov, I., Dym, O., Rozenberg, H., Koziol, A., Cuniasse, P., Dive, V., Arroyo, A.G., Irit, S., Israel Structural Proteomics Center (ISPC) | 2.6 | X-RAY DIFFRACTION | 0.253 | 0.197 | false | true | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
7cw0 | O | P | 0 | E | D | protein | protein | NA | NA | e2 glycoprotein | e1 glycoprotein | VIRUS/IMMUNE SYSTEM | 08/27/20 | Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG | CHIKUNGUNYA VIRUS; MUS MUSCULUS | mus musculus | mus musculus | chikungunya virus | chikungunya virus | Zhou, Q.F., Fox, J.M., Earnest, J.T., Ng, T.S., Kim, A.S., Fibriansah, G., Kostyuchenko, V.A., Shu, B., Diamond, M.S., Lok, S.M. | 5.9 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
7sp9 | B | null | 0 | A | protein | null | hyaluronan synthase | MEMBRANE PROTEIN | 11/02/21 | Chlorella virus Hyaluronan Synthase in the GlcNAc-primed channel-closed state | LAMA GLAMA; PARAMECIUM BURSARIA CHLORELLA VIRUS CZ-2 | lama glama | null | paramecium bursaria chlorella virus cz-2 | Maloney, F.P., Kuklewicz, J., Zimmer, J. | 2.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
3lrh | null | M | 0 | N | peptide | null | huntingtin | IMMUNE SYSTEM | 02/11/10 | Structure of anti-huntingtin VL domain in complex with huntingtin peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | null | homo sapiens | null | Schiefner, A., Chatwell, L., Skerra, A. | 2.6 | X-RAY DIFFRACTION | 0.278 | 0.216 | false | true | null | IGLV1 | Lambda | 0 | -10.022811 | Unknown | null | TBD |
7m7f | C | D | 0 | A | protein | null | eryai,6-deoxyerythronolide-b synthase erya3, modules 5 and6 chimera | BIOSYNTHETIC PROTEIN/IMMUNE SYSTEM | 03/28/21 | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: State 1 | SACCHAROPOLYSPORA ERYTHRAEA; HOMO SAPIENS | homo sapiens | homo sapiens | saccharopolyspora erythraea | Cogan, D.P., Zhang, K., Chiu, W., Khosla, C. | 3.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
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