pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1r24 | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 11/05/98 | FAB FROM MURINE IGG3 KAPPA | MUS MUSCULUS | mus musculus | mus musculus | null | Evans, S.V. | 3.1 | X-RAY DIFFRACTION | unknown | 0.245 | false | false | IGHV5 | IGKV10 | Kappa | null | null | null | null | null |
7vyt | H | L | 0 | T | protein | null | t-cell immunoreceptor with ig and itim domains | IMMUNE SYSTEM | 11/15/21 | Crystal structure of human TIGIT(23-129) in complex with the scFv fragment of anti-TIGIT antibody MG1131 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Jeong, B.-S., Nam, H., Kim, M., Oh, B.-H. | 1.53 | X-RAY DIFFRACTION | 0.219 | 0.201 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
2ajz | B | A | 0 | A | Hapten | ECG | 3-HYDROXY-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID METHYL ESTER | IMMUNE SYSTEM | 08/02/05 | Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with ecgonine methyl ester | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Zhu, X., Wilson, I.A. | 2.3 | X-RAY DIFFRACTION | 0.285 | 0.238 | false | false | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
3o11 | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 07/20/10 | Anti-beta-amyloid antibody c706 fab in space group c2 | MUS MUSCULUS, HOMO SAPIENS | mus musculus, homo sapiens | mus musculus, homo sapiens | null | Teplyakov, A., Obmolova, G., Malia, T., Gilliland, G.L. | 2.8 | X-RAY DIFFRACTION | 0.304 | 0.220 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
1yed | B | A | 0 | A | Hapten | PNB | 4-NITRO-BENZYLPHOSPHONOBUTANOYL-GLYCINE | CATALYTIC ANTIBODY | 04/15/97 | STRUCTURE OF A CATALYTIC ANTIBODY IGG2A FAB FRAGMENT (D2.4) | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Golinelli-Pimpaneau, B., Knossow, M. | 3.1 | X-RAY DIFFRACTION | 0.260 | 0.215 | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5d96 | C | B | 0 | A | protein | null | sulfhydryl oxidase 1 | IMMUNE SYSTEM | 08/18/15 | Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from an Antibody Targeting Mouse and Human QSOX1 | OTHER SEQUENCES; MUS MUSCULUS | other sequences | other sequences | mus musculus | Fass, D., Grossman, I. | 2.3 | X-RAY DIFFRACTION | 0.228 | 0.167 | false | true | IGHV2 | IGKV6 | Kappa | null | null | null | null | null |
5aam | A | a | 0 | C | protein | null | envelope protein | null | 07/27/15 | Structure of a redesigned cross-reactive antibody to dengue virus with increased in vivo potency | MUS MUSCULUS; DENGUE VIRUS | mus musculus | null | dengue virus | Wong, Y.H., Robinson, L.N., Lescar, J., Sasisekharan, R. | 2.49 | X-RAY DIFFRACTION | 0.2698 | 0.2196 | true | true | unknown | unknown | unknown | 0 | -11.48723 | SPR | null | TBD |
7rm3 | A | B | 0 | Q | peptide | null | peptide from circumsporozoite protein variant vk247 | ANTIMICROBIAL PROTEIN | 07/26/21 | Antibody 2E10.E9 in complex with P. vivax CSP peptide ANGAGNQPGANGAGNQPGANGAGGQAA | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | plasmodium vivax | Kucharska, I., Ivanochko, D., Julien, J.P. | 2.68 | X-RAY DIFFRACTION | 0.239 | 0.207 | false | true | IGHV9 | IGKV8 | Kappa | null | null | null | null | null |
5jxa | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 05/12/16 | Crystal structure of ligand-free VRC03 antigen-binding fragment. | HOMO SAPIENS | homo sapiens | homo sapiens | null | Zhou, T., Moquin, S., Joyce, M.G., Mascola, J.R., Kwong, P.D. | 1.6 | X-RAY DIFFRACTION | 0.180 | 0.160 | false | true | unknown | IGKV3 | Kappa | null | null | null | null | null |
5vxj | B | null | 0 | A | protein | null | invasin ipad | IMMUNE SYSTEM | 05/23/17 | 2.50 A resolution structure of IpaD from Shigella flexneri in complex with single-domain antibody JMK-E3 | SHIGELLA FLEXNERI; VICUGNA PACOS | vicugna pacos | null | shigella flexneri | Barta, M.L., Lovell, S., Battaile, K.P., Picking, W.D., Picking, W.L. | 2.5 | X-RAY DIFFRACTION | 0.259 | 0.196 | false | true | IGHV1 | null | null | null | null | null | null | null |
6k2i | A | null | 16 | null | null | null | null | AFB1-BINDING PROTEIN | 05/14/19 | Solution structure of camelid nanobody Nb11 against aflatoxin B1 | VICUGNA PACOS | vicugna pacos | null | null | Nie, Y., Li, S.L., He, T., Zhu, J., Yang, Y.H. | NOT | SOLUTION NMR | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
7c95 | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 06/04/20 | Crystal structure of the anti-human podoplanin antibody Fab fragment | MUS MUSCULUS | mus musculus | mus musculus | null | Nakamura, S., Suzuki, K., Ogasawara, S., Naruchi, K., Shimabukuro, J., Tukahara, N., Kaneko, M.K., Kato, Y., Murata, T. | 2.13 | X-RAY DIFFRACTION | 0.237 | 0.204 | false | false | IGHV5 | IGKV8 | Kappa | null | null | null | null | null |
5ihu | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 02/29/16 | Crystal structure of bovine Fab B11 | BOS TAURUS | bos taurus | bos taurus | null | Stanfield, R., Wilson, I. | 2.06 | X-RAY DIFFRACTION | 0.235 | 0.194 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
4xvs | H | L | 0 | G | protein | null | donor 45 01dg5 coree gp120 | Viral protein/Immune system | 01/27/15 | Crystal structure of HIV-1 donor 45 d45-01dG5 coreE gp120 with antibody 45-VRC01.H01+07.O-863513/45-VRC01.L01+07.O-110653 (VRC07_1995) | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Joyce, M.G., Mascola, J.R., Kwong, P.D. | 1.9 | X-RAY DIFFRACTION | 0.214 | 0.194 | false | true | unknown | IGKV3 | Kappa | null | null | null | null | null |
1f11 | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 05/18/00 | F124 FAB FRAGMENT FROM A MONOCLONAL ANTI-PRES2 ANTIBODY | MUS MUSCULUS | mus musculus | mus musculus | null | Saul, F.A., Vulliez-Le Normand, B., Passafiume, M., Riottot, M.M., Bentley, G.A. | 3.0 | X-RAY DIFFRACTION | 0.271 | 0.184 | false | false | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6wfz | A | B | 0 | C | peptide | null | npna3 peptide | IMMUNE SYSTEM | 04/04/20 | Crystal structure of Fab399 in complex with NPNA3 peptide from circumsporozoite protein | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | plasmodium falciparum | Pholcharee, T., Oyen, D., Wilson, I.A. | 1.84 | X-RAY DIFFRACTION | 0.225 | 0.186 | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
7n62 | H | L | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN/Immune System | 06/07/21 | SARS-CoV-2 Spike (2P) in complex with C12C9 Fab (NTD local reconstruction) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Windsor, I.W., Jenni, S., Bajic, G., Tong, P., Gautam, A.K., Wesemann, D.R., Harrison, S.C. | 4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
4dk6 | A | null | 0 | D | protein | null | rna-editing complex protein mp81 | RNA BINDING PROTEIN/IMMUNE SYSTEM | 02/03/12 | Structure of Editosome protein | LAMA GLAMA; TRYPANOSOMA BRUCEI | lama | null | trypanosoma brucei | Park, Y.-J., Hol, W. | 2.65 | X-RAY DIFFRACTION | 0.264 | 0.224 | false | true | IGHV1 | null | null | null | null | null | null | null |
6mek | H | L | 0 | C | protein | null | e2 glycoprotein | IMMUNE SYSTEM | 09/06/18 | Broadly neutralizing antibodies against HCV use a CDRH3 disulfide motif to recognize an E2 glycoprotein site that can be targeted for vaccine design | HEPACIVIRUS C; HOMO SAPIENS | homo sapiens | homo sapiens | hepacivirus c | Flyak, A.I., Bjorkman, P.J. | 3.1 | X-RAY DIFFRACTION | 0.290 | 0.223 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7bz2 | N | null | 0 | B | A | protein | protein | NA | NA | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | SIGNALING PROTEIN | 04/26/20 | Cryo-EM structure of the formoterol-bound beta2 adrenergic receptor-Gs protein complex. | HOMO SAPIENS; BOS TAURUS; LAMA GLAMA | lama glama | null | bos taurus | homo sapiens | Zhang, Y.N., Yang, F., Ling, S.L., Lv, P., Zhou, Y.X., Fang, W., Sun, W., Shi, P., Tian, C.L. | 3.82 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
7cyp | G | F | 0 | B | protein | null | sars-cov-2 spike glycoprotein | VIRAL PROTEIN | 09/04/20 | Complex of SARS-CoV-2 spike trimer with its neutralizing antibody HB27 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Wang, X., Zhu, L. | 3.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV5 | IGKV3 | Kappa | null | null | null | null | null |
5ihz | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 03/01/16 | Crystal structure of anti-gliadin 1002-1E01 Fab fragment | HOMO SAPIENS | homo sapiens | homo sapiens | null | Chen, X., Zhao, Y., Harlos, K., Snir, O., Sollid, L.M. | 1.64 | X-RAY DIFFRACTION | 0.229 | 0.200 | false | true | IGHV3 | IGLV4 | Lambda | null | null | null | null | null |
1eo8 | H | L | 0 | A | protein | null | hemagglutinin (ha1 chain) | Viral protein/Immune system | 03/22/00 | INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY | INFLUENZA A VIRUS (A/X-31(H3N2)); MUS MUSCULUS | mus musculus | mus musculus | influenza a virus (a/x-31(h3n2)) | Fleury, D., Gigant, B., Daniels, R.S., Skehel, J.J., Knossow, M., Bizebard, T. | 2.8 | X-RAY DIFFRACTION | 0.298 | 0.196 | false | false | IGHV1 | IGKV4 | Kappa | 0 | -10.87 | SPR | 22 | 10899782 |
6u59 | F | E | 0 | C | protein | null | sosip.664 gp120,sosip.664 gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 08/27/19 | HIV-1 B41 SOSIP.664 in complex with rabbit antibody 13B | HUMAN IMMUNODEFICIENCY VIRUS 1; ORYCTOLAGUS CUNICULUS | oryctolagus cuniculus | oryctolagus cuniculus | human immunodeficiency virus 1 | Yang, Y.R., Ward, A.B. | 3.86 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
4k3j | H | L | 0 | B | protein | null | hepatocyte growth factor beta chain | Transferase/Immune System/Growth Factor | 04/10/13 | Crystal structure of Onartuzumab Fab in complex with MET and HGF-beta | HOMO SAPIENS; SYNTHETIC CONSTRUCT | synthetic construct | synthetic construct | homo sapiens | Ma, X., Starovasnik, M.A. | 2.8 | X-RAY DIFFRACTION | 0.253 | 0.211 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -12.170174 | SPR | null | TBD |
3mj9 | H | L | 0 | A | protein | null | junctional adhesion molecule-like | IMMUNE SYSTEM | 04/12/10 | Crystal structure of JAML in complex with the stimulatory antibody HL4E10 | MUS MUSCULUS; CRICETULUS MIGRATORIUS | cricetulus migratorius | cricetulus migratorius | mus musculus | Verdino, P., Wilson, I.A. | 2.95 | X-RAY DIFFRACTION | 0.287 | 0.222 | false | false | IGHV2 | IGLV3 | Lambda | 0 | -11.06 | SPR | 25 | 21220118 |
1uz8 | B | A | 0 | H | carbohydrate | MAG | polysaccharide | IMMUNE SYSTEM | 03/05/04 | anti-Lewis X Fab fragment in complex with Lewis X | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Van Roon, A.M.M., Pannu, N.S., De Vrind, J.P.M., Hokke, C.H., Deelder, A.M., Van Der marel, G.A., Van Boom, J.H., Abrahams, J.P. | 1.8 | X-RAY DIFFRACTION | 0.247 | 0.210 | false | false | IGHV4 | IGKV2 | Kappa | 0.000011 | -6.764751 | Unknown | null | TBD |
7w55 | E | e | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(q) subunit alpha | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | SIGNALING PROTEIN | 11/29/21 | Cryo-EM structure of the neuromedin U-bound neuromedin U receptor 2-Gq protein complex | HOMO SAPIENS | homo sapiens | null | homo sapiens | homo sapiens | You, C., Xu, H.E., Jiang, Y. | 2.8 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
6x04 | D | null | 0 | C | protein | null | nucleoporin nup133 | STRUCTURAL PROTEIN | 05/15/20 | Nup133 (aa55-481) from S. cerevisiae bound by VHH-SAN5 | SACCHAROMYCES CEREVISIAE (STRAIN ATCC 204508 / S288C); VICUGNA PACOS | vicugna pacos | null | saccharomyces cerevisiae (strain atcc 204508 /s288c) | Nordeen, S.A., Schwartz, T.U. | 2.68 | X-RAY DIFFRACTION | 0.261 | 0.244 | false | true | IGHV1 | null | null | null | null | null | null | null |
4krm | H | null | 0 | G | protein | null | epidermal growth factor receptor | TRANSFERASE/IMMUNE SYSTEM | 05/16/13 | Nanobody/VHH domain 7D12 in complex with domain III of the extracellular region of EGFR, pH 3.5 | LAMA GLAMA; HOMO SAPIENS | lama glama | null | homo sapiens | Ferguson, K.M., Schmitz, K.R. | 2.655 | X-RAY DIFFRACTION | 0.244 | 0.208 | false | true | IGHV1 | null | null | null | null | null | null | null |
6ell | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 09/29/17 | FAB Fragment. AbVance: Increasing our knowledge of antibody structural space to enable faster and better decision making in antibody drug discovery | HOMO SAPIENS | homo sapiens | homo sapiens | null | Benz, J., Weigand, S., Dengl, S., Schlothauer, T., Auer, J., Ehler, A., Kettenberger, H., Lorenz, S., Hirschheydt, T., Georges, G. | 1.9 | X-RAY DIFFRACTION | 0.245 | 0.203 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
2igf | H | L | 0 | P | peptide | null | peptide (residues 69-87 of myohemerythrin) | IMMUNOGLOBULIN | 03/21/91 | CRYSTAL STRUCTURES OF AN ANTIBODY TO A PEPTIDE AND ITS COMPLEX WITH PEPTIDE ANTIGEN AT 2.8 ANGSTROMS | MUS MUSCULUS | mus musculus | mus musculus | null | Stanfield, R.L., Wilson, I.A. | 2.8 | X-RAY DIFFRACTION | unknown | 0.220 | false | true | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
3pnw | T | S | 0 | U | protein | null | tudor domain-containing protein 3 | PROTEIN BINDING/IMMUNE SYSTEM | 11/19/10 | Crystal Structure of the tudor domain of human TDRD3 in complex with an anti-TDRD3 FAB | HOMO SAPIENS, SYNTHETIC CONSTRUCT; HOMO SAPIENS | synthetic | synthetic | homo sapiens | Loppnau, P., Tempel, W., Wernimont, A.K., Lam, R., Ravichandran, M., Adams-Cioaba, M.A., Persson, H., Sidhu, S.S., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Cossar, D., Structural Genomics Consortium (SGC) | 2.05 | X-RAY DIFFRACTION | 0.264 | 0.223 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
1jnh | D | C | 0 | H | Hapten | ECO | ESTRADIOL-6 CARBOXYL-METHYL-OXIME | IMMUNE SYSTEM | 07/24/01 | Crystal Structure of Fab-Estradiol Complexes | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Monnet, C., Bettsworth, F., Stura, E.A., Le Du, M.-H., Menez, R., Derrien, L., Zinn-Justin, S., Gilquin, B., Sibai, G., Battail-Poirot, N., Jolivet, M., Menez, A., Arnaud, M., Ducancel, F., Charbonnier, J.B. | 2.85 | X-RAY DIFFRACTION | 0.253 | 0.198 | false | false | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
6mwx | C | D | 0 | B | protein | null | e2 | VIRUS/IMMUNE SYSTEM | 10/30/18 | CryoEM structure of Chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-69 Antibody | EASTERN EQUINE ENCEPHALITIS VIRUS; MUS MUSCULUS | mus musculus | mus musculus | eastern equine encephalitis virus | Hasan, S.S., Sun, C., Kim, A.S., Watanabe, Y., Chen, C.L., Klose, T., Buda, G., Crispin, M., Diamond, M.S., Klimstra, W.B., Rossmann, M.G. | 8.2 | ELECTRON MICROSCOPY | null | null | false | false | IGHV9 | IGLV1 | Lambda | null | null | null | null | null |
4fhb | D | null | 0 | A | protein | null | dihydrofolate reductase | Oxidoreductase/protein binding | 06/06/12 | Enhancing DHFR catalysis by binding of an allosteric regulator nanobody (Nb179) | ESCHERICHIA COLI; LAMA GLAMA | lama glama | null | escherichia coli | Oyen, D. | 2.8 | X-RAY DIFFRACTION | 0.296 | 0.217 | false | true | IGHV1 | null | null | null | null | null | null | null |
4ldl | B | null | 0 | A | protein | null | lysozyme, beta-2 adrenergic receptor | MEMBRANE PROTEIN/HYDROLASE | 06/24/13 | Structure of beta2 adrenoceptor bound to hydroxybenzylisoproterenol and an engineered nanobody | LAMA GLAMA; ENTEROBACTERIA PHAGE T4, HOMO SAPIENS | lama glama | null | enterobacteria phage t4, homo sapiens | Ring, A.M., Manglik, A., Kruse, A.C., Enos, M.D., Weis, W.I., Garcia, K.C., Kobilka, B.K. | 3.1 | X-RAY DIFFRACTION | 0.254 | 0.229 | false | true | IGHV1 | null | null | null | null | null | null | null |
4uin | H | L | 0 | H | Hapten | QI9 | Quinine | null | 03/30/15 | crystal structure of quinine-dependent Fab 314.3 with quinine | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Zhu, J., Zhu, J., Bougie, D.W., Aster, R.H., Springer, T.A. | 2.5 | X-RAY DIFFRACTION | 0.2544 | 0.2030 | false | false | IGHV1 | IGKV10 | Kappa | 0 | -10.395252 | Unknown | null | TBD |
3hc0 | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 05/05/09 | BHA10 IgG1 wild-type Fab - antibody directed at human LTBR | HOMO SAPIENS | homo sapiens | homo sapiens | null | Arndt, J.W., Jordan, J.L., Lugovskoy, A., Wang, D. | 1.9 | X-RAY DIFFRACTION | 0.206 | 0.180 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6uun | N | null | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 10/30/19 | CryoEM Structure of the active Adrenomedullin 1 receptor G protein complex with adrenomedullin peptide | HOMO SAPIENS; LAMA GLAMA; SYNTHETIC CONSTRUCT | lama glama | null | homo sapiens | homo sapiens | Belousoff, M.J., Liang, Y.L., Sexton, P., Danev, R. | 3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
6i6j | C | null | 0 | A | protein | null | er lumen protein-retaining receptor 2 | MEMBRANE PROTEIN | 11/15/18 | Crystal structure of the KDEL receptor bound to synthetic nanobody. | GALLUS GALLUS; UNIDENTIFIED | unidentified | null | gallus gallus | Braeuer, P., Newstead, S. | 2.23 | X-RAY DIFFRACTION | 0.247 | 0.211 | false | true | IGHV1 | null | null | null | null | null | null | null |
7dhi | N | null | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | SIGNALING PROTEIN | 11/15/20 | Cryo-EM structure of the partial agonist salbutamol-bound beta2 adrenergic receptor-Gs protein complex. | HOMO SAPIENS; BOS TAURUS; LAMA GLAMA | lama glama | null | homo sapiens | bos taurus | Yang, F., Ling, S.L., Zhou, Y.X., Zhang, Y.N., Lv, P., Liu, S.L., Fang, W., Sun, W.J., Hu, L.Y.A. | 3.26 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
6iyn | A | null | 13 | null | null | null | null | AFLATOXIN B1-BINDING PROTEIN | 12/17/18 | Solution structure of camelid nanobody Nb26 against aflatoxin B1 | VICUGNA PACOS | vicugna pacos | null | null | Nie, Y., He, T., Zhu, J., Li, S.L., Hu, R., Yang, Y.H. | NOT | SOLUTION NMR | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
3bgf | B | C | 0 | A | protein | null | spike protein s1 | Viral Protein/Immune System | 11/26/07 | X-ray crystal structure of the SARS coronavirus spike receptor binding domain in complex with F26G19 Fab | SARS CORONAVIRUS; MUS MUSCULUS | mus musculus | mus musculus | sars coronavirus | Pak, J.E., Rini, J.M. | 3.0 | X-RAY DIFFRACTION | 0.286 | 0.234 | false | false | IGHV1 | IGKV9 | Kappa | 0 | -10.34 | SPR | 25 | 19324051 |
6itc | V | null | 0 | Y | E | protein | protein | NA | NA | protein translocase subunit secy | protein translocase subunit sece | PROTEIN TRANSPORT | 11/21/18 | Structure of a substrate engaged SecA-SecY protein translocation machine | BACILLUS SUBTILIS (STRAIN 168); GEOBACILLUS THERMODENITRIFICANS (STRAIN NG80-2); LAMA GLAMA; ESCHERICHIA COLI; AEQUOREA VICTORIA | lama glama | null | geobacillus thermodenitrificans (strain ng80-2) | geobacillus thermodenitrificans (strain ng80-2) | Ma, C.Y., Wu, X.F., Sun, D.J., Park, E.Y., Rapoport, T.A., Gao, N., Long, L. | 3.45 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
6q23 | G | I | 0 | D | protein | null | neuraminidase | VIRAL PROTEIN,HYDROLASE/IMMUNE SYSTEM | 08/06/19 | Crystal structure of human 1G01 Fab in complex with influenza virus neuraminidase from A/California/04/2009 (H1N1) | INFLUENZA A VIRUS (A/CALIFORNIA/04/2009 (H1N1); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus (a/california/04/2009 (h1n1) | Zhu, X., Wilson, I.A. | 3.27 | X-RAY DIFFRACTION | 0.241 | 0.196 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5cma | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 07/16/15 | Anti-B7-H3 monoclonal antibody ch8H9 Fab fragment | MUS MUSCULUS | mus musculus | mus musculus | null | Ahmed, M., Goldgur, Y., Cheng, M., Cheung, N.K. | 2.5 | X-RAY DIFFRACTION | 0.261 | 0.208 | false | true | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
2mcp | H | L | 0 | H | Hapten | PC | PHOSPHOCHOLINE | IMMUNOGLOBULIN | 10/15/84 | REFINED CRYSTAL STRUCTURE OF THE MC/PC603 FAB-PHOSPHOCHOLINE COMPLEX AT 3.1 ANGSTROMS RESOLUTION | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Padlan, E.A., Cohen, G.H., Davies, D.R. | 3.1 | X-RAY DIFFRACTION | unknown | 0.185 | false | true | IGHV7 | IGKV8 | Kappa | null | null | null | null | null |
7mw3 | F | G | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN/Immune System | 05/15/21 | Structure of the SARS-CoV-2 Spike trimer with two RBDs down in complex with the Fab fragment of human neutralizing antibody clone 6 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Hu, Y., Xiong, Y. | 3.15 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
1yek | H | L | 0 | H | Hapten | NPO | P-NITROPHENOL | IMMUNE SYSTEM | 08/13/98 | CATALYTIC ANTIBODY D2.3 COMPLEX | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Gigant, B., Knossow, M. | 2.1 | X-RAY DIFFRACTION | 0.237 | 0.200 | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6nbi | N | null | 0 | A | B | protein | protein | NA | NA | gs protein alpha subunit | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | SIGNALING PROTEIN | 12/07/18 | Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein | HOMO SAPIENS; BOS TAURUS; RATTUS NORVEGICUS; SYNTHETIC CONSTRUCT | synthetic construct | null | bos taurus | rattus norvegicus | Zhao, L.-H., Ma, S., Sutkeviciute, I., Shen, D.-D., Zhou, X.E., de Waal, P.P., Li, C.-Y., Kang, Y., Clark, L.J., Jean-Alphonse, F.G., White, A.D., Xiao, K., Yang, D., Jiang, Y., Watanabe, T., Gardella, T.J., Melcher, K., Wang, M.-W., Vilardaga, J.-P., Xu, H.E., Zhang, Y. | 4.0 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
3dgg | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 06/13/08 | Crystal structure of FabOX108 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Ren, J., Nettleship, J.E., Owens, R.J., Oxford Protein Production Facility (OPPF) | 2.3 | X-RAY DIFFRACTION | 0.246 | 0.187 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
6bzy | H | L | 0 | B | peptide | null | e2 as412 peptide | IMMUNE SYSTEM | 12/26/17 | Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the 22D11 broadly neutralizing antibody | MUS MUSCULUS; HEPACIVIRUS C | mus musculus | mus musculus | hepacivirus c | Tzarum, N., Alemn, F., Wilson, I.A., Law, M. | 1.6 | X-RAY DIFFRACTION | 0.218 | 0.188 | false | true | IGHV2 | IGKV3 | Kappa | null | null | null | null | null |
5f3h | C | D | 0 | I | protein | null | growth/differentiation factor 8 | Signaling Protein/Immune System | 12/02/15 | Structure of myostatin in complex with humanized RK35 antibody | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Parris, K.D., Mosyak, L. | 2.7 | X-RAY DIFFRACTION | 0.270 | 0.218 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3rif | J | M | 0 | E | protein | null | avermectin-sensitive glutamate-gated chloride channel gluclalpha | transport protein/immune system | 04/13/11 | C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab, ivermectin and glutamate. | CAENORHABDITIS ELEGANS; MUS MUSCULUS | mus musculus | mus musculus | caenorhabditis elegans | Hibbs, R.E., Gouaux, E. | 3.345 | X-RAY DIFFRACTION | 0.271 | 0.248 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
4tyu | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 07/09/14 | Homodimeric Single Domain Antibody (sdAb) against Staphylococcal enterotoxin B (SEB) | LAMA GLAMA | lama glama | null | null | Legler, P.M. | 2.13 | X-RAY DIFFRACTION | 0.263 | 0.239 | false | true | IGHV1 | null | null | null | null | null | null | null |
5x8l | J | O | 0 | E | protein | null | programmed cell death 1 ligand 1 | IMMUNE SYSTEM | 03/03/17 | PD-L1 in complex with atezolizumab | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Heo, Y.S., Lee, H.T. | 3.1 | X-RAY DIFFRACTION | 0.256 | 0.208 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
2zuq | C | B | 0 | A | protein | null | disulfide bond formation protein b | Oxidoreductase/IMMUNE SYSTEM | 10/28/08 | Crystal structure of DsbB-Fab complex | ESCHERICHIA COLI; MUS MUSCULUS | mus musculus | mus musculus | escherichia coli | Inaba, K., Suzuki, M., Murakami, S. | 3.3 | X-RAY DIFFRACTION | 0.351 | 0.275 | false | false | IGHV5 | IGKV8 | Kappa | null | null | null | null | null |
6vmk | H | G | 0 | I | protein | null | fab y49r heavy chain | HYDROLASE/IMMUNE SYSTEM | 01/28/20 | Crystal structure of human Complement Factor D with anti-Factor D Fab 20D12 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Wu, P., Harris, S.F., Eigenbrot, C. | 3.01 | X-RAY DIFFRACTION | 0.215 | 0.174 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
4zg1 | F | null | 0 | null | null | null | null | PROTEIN BINDING | 04/22/15 | Crystal structure of a nanobody raised against KDM5b | LAMA GLAMA | lama glama | null | null | Wiuf, A., Kristensen, O., Gajhede, M. | 1.85 | X-RAY DIFFRACTION | 0.235 | 0.186 | false | true | IGHV1 | null | null | null | null | null | null | null |
6ejm | I | i | 0 | A | protein | null | cd81 antigen | CELL ADHESION | 09/22/17 | CRYSTAL STRUCTURE OF HUMAN CD81 LARGE EXTRACELLULAR LOOP IN COMPLEX WITH SINGLE CHAIN FV FRAGMENT 5 | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | Kuglstatter, A., Harris, S.F., Villasenor, A. | 2.15 | X-RAY DIFFRACTION | 0.278 | 0.215 | true | true | unknown | unknown | unknown | 0 | -12.367557 | SPR | null | TBD |
6n16 | H | L | 0 | F | peptide | null | hiv fusion peptide (512-519) | IMMUNE SYSTEM | 11/08/18 | Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-b.01 in complex with HIV fusion peptide (residue 512-519) | PLATYRRHINI; SYNTHETIC CONSTRUCT | platyrrhini | platyrrhini | human immunodeficiency virus 1 | Xu, K., Wang, Y., Kwong, P.D. | 2.302 | X-RAY DIFFRACTION | 0.274 | 0.222 | false | true | IGHV4 | IGKV2 | Kappa | null | null | null | null | null |
7l7d | H | L | 0 | E | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 12/28/20 | Crystal structure of SARS-CoV-2 spike RBD in complex with human monoclonal antibody AZD8895 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Dong, J., Crowe, J.E. | 2.5 | X-RAY DIFFRACTION | 0.231 | 0.185 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7c2e | N | null | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 05/07/20 | GLP-1R-Gs complex structure with a small molecule full agonist | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | homo sapiens | Ma, H., Yuan, D.P., Huang, W., Wenge, Z., Xu, E. | 4.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
6wm9 | E | F | 0 | D | protein | null | reticulocyte binding protein 2b | CELL INVASION | 04/20/20 | Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 237235 | PLASMODIUM VIVAX (STRAIN SALVADOR I); HOMO SAPIENS | homo sapiens | homo sapiens | plasmodium vivax (strain salvador i) | Chan, L.J., Dietrich, M.H., Tham, W.H. | 2.45 | X-RAY DIFFRACTION | 0.279 | 0.223 | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
4r4n | H | L | 0 | A | m | protein | peptide | NA | NA | m48u1 peptide | unknown | VIRAL PROTEIN/IMMUNE SYSTEM/INHIBITOR | 08/19/14 | Crystal structure of the anti-hiv-1 antibody 2.2c in complex with hiv-1 93ug037 gp120 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | synthetic construct | Acharya, P., Louder, R., Kwong, P.D. | 3.56 | X-RAY DIFFRACTION | 0.328 | 0.296 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
6a79 | I | M | 0 | B | protein | null | roundabout homolog 1 | IMMUNE SYSTEM | 07/02/18 | Crystal structure of the fifth immunoglobulin domain (Ig5) of human Robo1 in complex with the mutant scFv fragment (P103A) of murine monoclonal antibody B5209B | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Mizohata, E., Nakayama, T., Kado, Y., Yokota, Y., Inoue, T. | 2.31 | X-RAY DIFFRACTION | 0.295 | 0.273 | false | true | IGHV5 | IGKV12 | Kappa | null | null | null | null | null |
6gkd | Q | null | 0 | O | protein | null | cystic fibrosis transmembrane conductance regulator | HYDROLASE | 05/18/18 | human NBD1 of CFTR in complex with nanobodies D12 and G3a | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Sigoillot, M., Overtus, M., Grodecka, M., Scholl, D., Garcia-Pino, A., Laeremans, T., He, L., Pardon, E., Hildebrandt, E., Urbatsch, I., Steyaert, J., Riordan, J.R., Govaerts, C. | 2.99 | X-RAY DIFFRACTION | 0.235 | 0.204 | false | true | IGHV1 | null | null | null | null | null | null | null |
5f72 | S | s | 0 | K | protein | null | kelch-like ech-associated protein 1 | DE NOVO PROTEIN | 12/07/15 | De novo design and crystallographic validation of antibodies targeting a pre-selected epitope | HOMO SAPIENS | homo sapiens | null | homo sapiens | Liu, X., Taylor, R.D., Griffin, L., Coker, S., Adams, R., Ceska, T., Shi, J., Lawson, A.D.G., Baker, T. | 1.85 | X-RAY DIFFRACTION | 0.265 | 0.223 | true | true | unknown | unknown | unknown | null | null | null | null | null |
6oe4 | B | C | 0 | A | protein | null | fusion glycoprotein f0 | Viral protein/immune system | 03/27/19 | Prefusion RSV F monomer bound by neutralizing antibody CR9501 | HUMAN RESPIRATORY SYNCYTIAL VIRUS A (STRAIN A2); HOMO SAPIENS | homo sapiens | homo sapiens | human respiratory syncytial virus a (straina2) | McLellan, J.S., Gilman, M.S.A. | 3.3 | X-RAY DIFFRACTION | 0.259 | 0.212 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
4rfe | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 09/25/14 | Crystal structure of ADCC-potent ANTI-HIV-1 Rhesus macaque antibody JR4 Fab | MACACA MULATTA | macaca mulatta | macaca mulatta | null | Wu, X., Gohain, N., Tolbert, W.D., Pazgier, M. | 1.91 | X-RAY DIFFRACTION | 0.246 | 0.192 | false | true | IGHV4 | IGLV1 | Lambda | null | null | null | null | null |
6h6y | E | null | 0 | A | protein | null | capsid protein vp1 | VIRAL PROTEIN | 12/19/18 | GI.1 human norovirus protruding domain in complex with Nano-7 | NORWALK VIRUS (STRAIN GI/HUMAN/UNITED STATES/NORWALK/1968); VICUGNA PACOS | vicugna pacos | null | norwalk virus (strain gi/human/unitedstates/norwalk/1968) | Kilic, T., Ruoff, K., Hansman, G.S. | 1.58 | X-RAY DIFFRACTION | 0.175 | 0.155 | false | true | IGHV1 | null | null | null | null | null | null | null |
3mck | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 03/29/10 | Crystal structure of anti-beta-amyloid antibody C705 | MUS MUSCULUS | mus musculus | mus musculus | null | Teplyakov, A., Obmolova, G., Gilliland, G.L. | 2.3 | X-RAY DIFFRACTION | 0.254 | 0.203 | false | true | IGHV8 | IGKV1 | Kappa | null | null | null | null | null |
7dcc | B | M | 0 | I | protein | null | spike glycoprotein | VIRAL PROTEIN | 10/24/20 | S-3C1-F3b structure, all the three RBDs are in the up conformation and each of them associates with a 3C1 Fab | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; MUS MUSCULUS | mus musculus | mus musculus | severe acute respiratory syndrome coronavirus2 | Cong, Y., Liu, C.X. | 4.3 | ELECTRON MICROSCOPY | null | null | false | false | IGHV3 | IGKV6 | Kappa | null | null | null | null | null |
1um6 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 09/23/03 | catalytic antibody 21h3 | MUS MUSCULUS | mus musculus | mus musculus | null | Beuscher IV, A.E., Reuter, J., Olson, A.J., Romesberg, F.E., Schultz, P.G., Wirsching, P., Janda, K.D., Lerner, R.A., Stevens, R.C. | 1.8 | X-RAY DIFFRACTION | 0.257 | 0.231 | false | true | IGHV1 | IGKV9 | Kappa | null | null | null | null | null |
1uz6 | P | M | 0 | null | null | null | null | IMMUNE SYSTEM | 03/05/04 | anti-Lewis X Fab fragment uncomplexed | MUS MUSCULUS | mus musculus | mus musculus | null | Van Roon, A.M.M., Pannu, N.S., De Vrind, J.P.M., Hokke, C.H., Deelder, A.M., Van Der marel, G.A., Van Boom, J.H., Abrahams, J.P. | 2.05 | X-RAY DIFFRACTION | 0.244 | 0.198 | false | false | IGHV4 | IGKV2 | Kappa | null | null | null | null | null |
4o5i | Q | R | 0 | E | protein | null | hemagglutinin ha1 chain | VIRAL PROTEIN/IMMUNE SYSTEM | 12/19/13 | Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/361/2011 (H3N2) influenza hemagglutinin | HOMO SAPIENS; INFLUENZA A VIRUS | homo sapiens | homo sapiens | influenza a virus | Lee, P.S., Wilson, I.A. | 6.501 | X-RAY DIFFRACTION | 0.248 | 0.201 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
4ocm | C | null | 0 | B | A | protein | protein | NA | NA | 26s proteasome regulatory subunit rpn11 | 26s proteasome regulatory subunit rpn8 | HYDROLASE, PROTEIN BINDING | 01/09/14 | Crystal Structure of the Rpn8-Rpn11 MPN domain heterodimer, crystal form Ib | SACCHAROMYCES CEREVISIAE; LAMA GLAMA | lama glama | null | saccharomyces cerevisiae | saccharomyces cerevisiae | Pathare, G.R., Bracher, A. | 1.99 | X-RAY DIFFRACTION | 0.262 | 0.216 | false | true | IGHV1 | null | null | null | null | null | null | null |
6gwq | B | null | 0 | A | protein | null | plasminogen activator inhibitor-1 | HYDROLASE | 06/25/18 | Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-stab) in Complex with an Inhibitory Nanobody (VHH-2g-42) | HOMO SAPIENS; VICUGNA PACOS | vicugna pacos | null | homo sapiens | Sillen, M., Weeks, S.D., Strelkov, S.V., Declerck, P.J. | 2.32 | X-RAY DIFFRACTION | 0.230 | 0.206 | false | true | IGHV1 | null | null | null | null | null | null | null |
4hem | E | null | 0 | C | B | protein | protein | NA | NA | bpp | bpp | VIRAL PROTEIN | 10/04/12 | Llama vHH-02 binder of ORF49 (RBP) from lactococcal phage TP901-1 | LACTOCOCCUS PHAGE TP901-1; LAMA GLAMA | lama glama | null | lactococcus phage tp901-1 | lactococcus phage tp901-1 | Desmyter, A., Spinelli, S., Farenc, C., Blangy, S., Bebeacua, C., van Sinderen, D., Mahony, J., Cambillau, C. | 1.65 | X-RAY DIFFRACTION | 0.177 | 0.167 | false | true | IGHV1 | null | null | null | null | null | null | null |
6o3g | H | L | 0 | S | peptide | null | meper peptide, region 671-683 of hiv-1 gp41 | IMMUNE SYSTEM | 02/26/19 | Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1 in complex with its MPER peptide epitope (region 671-683 of HIV-1 gp41). | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Irimia, A., Wilson, I.A. | 3.645 | X-RAY DIFFRACTION | 0.289 | 0.260 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6o2c | A | B | 0 | C | peptide | null | circumsporozoite protein | IMMUNE SYSTEM | 02/22/19 | Crystal structure of 4493 Fab in complex with circumsporozoite protein NANP3 and anti-kappa VHH domain | HOMO SAPIENS; LAMA GLAMA; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | plasmodium falciparum | Scally, S.W., Bosch, A., Prieto, K., Murugan, R., Wardemann, H., Julien, J.P. | 2.017 | X-RAY DIFFRACTION | 0.195 | 0.162 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
4s1d | H | L | 0 | H | Hapten | 41M | N~6~-{5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}-L-lysinamide | IMMUNE SYSTEM | 01/13/15 | Structure of IgG1 Fab fragment in complex with Biotincytidinamide | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Dengl, S., Hoffmann, E., Grote, M., Wagner, C., Mundigl, O., Georges, G., Theorey, I., Stubenrauch, K.-G., Bujotzek, A., Josel, H.-P., Dziadek, S., Benz, J., Brinkmann, U. | 2.5 | X-RAY DIFFRACTION | 0.274 | 0.225 | false | true | IGHV14 | IGKV12 | Kappa | null | null | null | null | null |
5zud | E | D | 0 | C | A | B | protein | protein | protein | NA | NA | NA | vp3 | capsid protein vp1 | vp2 | VIRUS LIKE PARTICLE | 05/07/18 | Fit R10 Fab coordinates into the cryo-EM of EV71 in complex with D6 | ENTEROVIRUS A71; MUS MUSCULOIDES | mus musculoides | mus musculoides | enterovirus a71 | enterovirus a71 | enterovirus a71 | Wang, X., Zhu, L., Wang, N. | 4.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
6mhg | D | Q | 0 | E | protein | null | circumsporozoite protein | IMMUNE SYSTEM | 09/17/18 | Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts | PLASMODIUM FALCIPARUM; HOMO SAPIENS | homo sapiens | homo sapiens | plasmodium falciparum | Cottrell, C.A., Torres, J.L., Ward, A.B. | 3.57 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
5mu2 | C | D | 0 | Q | peptide | null | synthetic peptide containing the cii583-591 epitope ofcollagen type ii | IMMUNE SYSTEM | 01/12/17 | ACC1 Fab fragment in complex with CII583-591 (CG10) | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | mus musculus | Dobritzsch, D., Holmdahl, R., Ge, C. | 2.7 | X-RAY DIFFRACTION | 0.228 | 0.206 | false | false | IGHV6 | IGKV3 | Kappa | null | null | null | null | null |
6mei | H | L | 0 | C | protein | null | e2 glycoprotein | IMMUNE SYSTEM | 09/06/18 | Broadly neutralizing antibodies against HCV use a CDRH3 disulfide motif to recognize an E2 glycoprotein site that can be targeted for vaccine design | HEPACIVIRUS C; HOMO SAPIENS | homo sapiens | homo sapiens | hepacivirus c | Flyak, A.I., Bjorkman, P.J. | 2.9 | X-RAY DIFFRACTION | 0.277 | 0.208 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
4yhi | H | L | 0 | H | Hapten | 4CC | N-[(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazol-5-yl)carbonyl]-N-pyridin-2-yl-beta-alanine | IMMUNE SYSTEM | 02/27/15 | Reversal Agent for Dabigatran | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Schiele, F., Nar, H. | 1.9 | X-RAY DIFFRACTION | 0.215 | 0.181 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6dwi | H | G | 0 | H | carbohydrate | HD4 | 4-O-[2-acetamido-2-deoxy-beta-D-glucopyranosyl]-1-O-phosphono-D-ribitol | IMMUNE SYSTEM | 06/26/18 | Structure of the 4462 Antibody Fab fragment bound to a Staphylococcus aureus wall techoic acid analog | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Fong, R., Lupardus, P.J. | 2.39 | X-RAY DIFFRACTION | 0.249 | 0.203 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
7so9 | M | L | 0 | K | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 10/29/21 | SARS-CoV-2 S B.1.617.2 delta variant + S2M11 + S2L20 Global Refinement | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | McCallum, M., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 2.4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6opq | K | N | 0 | D | protein | null | envelope glycoprotein gp160 | VIRAL PROTEIN/Immune System | 04/25/19 | CD4- and 17-bound HIV-1 Env B41 SOSIP frozen with LMNG | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Ozorowski, G., Torres, J.L., Ward, A.B. | 3.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5tdo | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 09/19/16 | Crystal structure of the Fab fragment of anti-HER2 antibody 4D5 with redesigned heavy and light chain interfaces | HOMO SAPIENS | homo sapiens | homo sapiens | null | Yin, Y., Carter, P.J. | 1.61 | X-RAY DIFFRACTION | 0.267 | 0.237 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7u0c | H | L | 0 | null | null | null | null | ANTIVIRAL PROTEIN,IMMUNE SYSTEM | 02/17/22 | Crystal structure of broadly neutralizing antibody HEPC3.4 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Flyak, A.I., Bjorkman, P.J. | 3.3 | X-RAY DIFFRACTION | 0.260 | 0.215 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6k5a | C | D | 0 | A | protein | null | h(+)/cl(-) exchange transporter clca | MEMBRANE PROTEIN | 05/28/19 | Crystal structure of the E148D/R147A/F317A mutant in presence of 200 mM NaBr | ESCHERICHIA COLI MS 117-3; MUS MUSCULUS | mus musculus | mus musculus | escherichia coli ms 117-3 | Park, K., Lim, H.H. | 3.162 | X-RAY DIFFRACTION | 0.276 | 0.222 | false | true | IGHV4 | IGKV4 | Kappa | null | null | null | null | null |
5ikc | H | L | 0 | N | protein | null | neuronal migration protein doublecortin | TRANSFERASE | 03/03/16 | X-RAY STRUCURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN in complex with FAB | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Ruf, A., Stihle, M., Benz, J., Thoma, R., Rudolph, M.G. | 2.06 | X-RAY DIFFRACTION | 0.265 | 0.198 | false | true | IGHV14 | IGKV6 | Kappa | 0 | -10.325467 | SPR | null | TBD |
4hpo | H | L | 0 | P | peptide | null | envelope glycoprotein gp160 | Immune System/Viral Protein | 10/24/12 | Crystal structure of RV144-elicited antibody CH58 in complex with V2 peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | McLellan, J.S., Gorman, J., Haynes, B.F., Kwong, P.D. | 1.694 | X-RAY DIFFRACTION | 0.211 | 0.185 | false | true | IGHV5 | IGLV6 | Lambda | null | null | null | null | null |
7l0l | I | K | 0 | F | D | protein | protein | NA | NA | hemagglutinin ha2 chain | hemagglutinin ha1 chain | IMMUNE SYSTEM/Viral protein | 12/11/20 | Cryo-EM structure of the VRC316 clinical trial, vaccine-elicited, human antibody 316-310-1B11 in complex with an H2 CAN05 HA trimer | HOMO SAPIENS; INFLUENZA A VIRUS (A/CANADA/720/2005(H2N2)) | homo sapiens | homo sapiens | influenza a virus (a/canada/720/2005(h2n2)) | influenza a virus (a/canada/720/2005(h2n2)) | Gorman, J., Kwong, P.D. | 2.85 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6nf2 | C | D | 0 | G | protein | null | envelope glycoprotein gp120 | IMMUNE SYSTEM | 12/18/18 | Cryo-EM structure of vaccine-elicited antibody 0PV-c.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Gorman, J., Kwong, P.D. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV3 | Kappa | null | null | null | null | null |
6e9g | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 08/01/18 | The crystal structure of bovine ultralong antibody BOV-2 | BOS TAURUS | bos taurus | bos taurus | null | Dong, J., Crowe, J.E. | 2.904 | X-RAY DIFFRACTION | 0.263 | 0.220 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
5kem | G | H | 0 | F | protein | null | ebola secreted glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 06/09/16 | EBOV sGP in complex with variable Fab domains of IgGs c13C6 and BDBV91 | HOMO SAPIENS; ZAIRE EBOLAVIRUS | homo sapiens | homo sapiens | zaire ebolavirus | Pallesen, J., Murin, C.D., de Val, N., Cottrell, C.A., Hastie, K.M., Turner, H.L., Fusco, M.L., Flyak, A.I., Zeitlin, L., Crowe Jr., J.E., Andersen, K.G., Saphire, E.O., Ward, A.B. | 5.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
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