pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3b2u | W | X | 0 | V | protein | null | epidermal growth factor receptor | IMMUNE SYSTEM/TRANSFERASE | 10/19/07 | Crystal structure of isolated domain III of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Ferguson, K.M., Li, S., Kussie, P. | 2.58 | X-RAY DIFFRACTION | 0.291 | 0.227 | false | true | IGHV4 | IGKV3 | Kappa | 0 | -12.27 | SPR | 25 | 18275813 |
2ih1 | A | B | 0 | C | protein | null | voltage-gated potassium channel | MEMBRANE PROTEIN | 09/25/06 | Ion selectivity in a semi-synthetic K+ channel locked in the conductive conformation | STREPTOMYCES LIVIDANS; MUS MUSCULUS | mus musculus | mus musculus | streptomyces lividans | Valiyaveetil, F.I., Leonetti, M., Muir, T.W., MacKinnon, R. | 2.4 | X-RAY DIFFRACTION | 0.251 | 0.233 | false | false | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
7r98 | F | null | 0 | C | protein | null | nucleoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 06/28/21 | Structure of the SARS-CoV-2 N protein RNA-binding domain bound to single-domain antibody B6 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; LAMA GLAMA | lama glama | null | severe acute respiratory syndrome coronavirus2 | Corbett, K.D., Ye, Q. | 2.51 | X-RAY DIFFRACTION | 0.273 | 0.226 | false | true | IGHV1 | null | null | null | null | null | null | null |
7faf | d | c | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 07/06/21 | S protein of SARS-CoV-2 in complex bound with P36-5D2 (state1) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhang, L., Wang, X., Zhang, S., Shan, S. | 3.69 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7rd3 | A | B | 0 | C | peptide | null | circumsporozoite protein | IMMUNE SYSTEM | 07/09/21 | Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m42.126 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | plasmodium falciparum | Xu, K., Kwong, P.D. | 1.81 | X-RAY DIFFRACTION | 0.260 | 0.216 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
4gw5 | D | C | 0 | null | null | null | null | Immune system | 08/31/12 | cQYN meditope - Cetuximab Fab | MURINAE,HOMO SAPIENS; SYNTHETIC CONSTRUCT | murinae,homo sapiens | murinae,homo sapiens | null | Donaldson, J.M., Zer, C., Avery, K.N., Bzymek, K.P., Horne, D.A., Williams, J.C. | 2.2 | X-RAY DIFFRACTION | 0.222 | 0.174 | false | true | IGHV2 | IGKV5 | Kappa | 0.000004 | -7.443223 | Unknown | null | TBD |
3hb3 | C | D | 0 | B | protein | null | cytochrome c oxidase subunit 2 | OXIDOREDUCTASE | 05/04/09 | High resolution crystal structure of Paracoccus denitrificans cytochrome c oxidase | PARACOCCUS DENITRIFICANS; MUS MUSCULUS | mus musculus | mus musculus | paracoccus denitrificans | Koepke, J., Angerer, H., Peng, G. | 2.25 | X-RAY DIFFRACTION | 0.280 | 0.218 | false | true | IGHV5 | IGKV12 | Kappa | null | null | null | null | null |
7eh3 | A | null | 9 | null | null | null | null | IMMUNE SYSTEM | 03/28/21 | Structure of Nanobody Nb23 in solution using NMR spectroscopy | LAMA GLAMA | lama glama | null | null | Percipalle, M., Hunashal, Y., Esposito, G., Fogolari, F. | NOT | SOLUTION NMR | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
6xw4 | C | null | 0 | A | protein | null | capsid protein | VIRAL PROTEIN | 01/23/20 | Crystal structure of murine norovirus P domain in complex with Nanobody NB-5867 | MURINE NOROVIRUS 1; VICUGNA PACOS | vicugna pacos | null | murine norovirus 1 | Kilic, T., Sabin, C., Hansman, G. | 2.19 | X-RAY DIFFRACTION | 0.218 | 0.173 | false | true | IGHV1 | null | null | null | null | null | null | null |
2kqn | null | B | 14 | null | null | null | null | IMMUNE SYSTEM | 11/11/09 | Solution structure of the AL-09 H87Y immunoglobulin light chain variable domain | HOMO SAPIENS | null | homo sapiens | null | Volkman, B.F., Peterson, F.C., Ramirez-Alvarado, M., Baden, E.M. | NOT | SOLUTION NMR | null | null | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
5yoy | R | O | 0 | J | protein | null | tumor necrosis factor | IMMUNE SYSTEM | 10/31/17 | Crystal structure of the human tumor necrosis factor in complex with golimumab Fv | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Ono, M., Horita, S., Sato, Y., Nomura, Y., Iwata, S., Nomura, N. | 2.727 | X-RAY DIFFRACTION | 0.234 | 0.190 | false | true | IGHV3 | IGKV3 | Kappa | 0 | -14.658431 | Unknown | null | TBD |
4ngh | H | L | 0 | P | peptide | null | modified fragment of hiv glycoprotein (gp41) | IMMUNE SYSTEM | 11/01/13 | Crystal structure of the HIV-1 neutralizing antibody 4E10 Fab fragment in complex with a hydrocarbon-stapled peptide containing the 4e10 epitope on gp41 and a tethered phosphate moiety. | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | null | Irimia, A., Wilson, I.A. | 2.68 | X-RAY DIFFRACTION | 0.223 | 0.169 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5vf6 | A | a | 0 | null | null | null | null | IMMUNE SYSTEM | 04/06/17 | Crystal structure of single chain variable fragment (scFv45). | GALLUS GALLUS | gallus gallus | null | null | Shrestha, O.K., Tocilj, A., Joshua-Tor, L., Tonks, N.K. | 1.635 | X-RAY DIFFRACTION | 0.196 | 0.172 | true | true | unknown | unknown | unknown | null | null | null | null | null |
5mv4 | R | S | 0 | T | peptide | null | synthetic peptide containing the citrullinated collagentype ii epitope cii616-639,collagen alpha-1(ii) chain,synthetic peptide containing the citrullinated collagen type ii epitope cii616- 639 | IMMUNE SYSTEM | 01/15/17 | ACC1 Fab fragment in complex with citrullinated CII616-639 epitope of collagen type II (ptm23) | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | mus musculus | Dobritzsch, D., Holmdahl, R., Ge, C. | 2.9 | X-RAY DIFFRACTION | 0.247 | 0.232 | false | false | IGHV6 | IGKV3 | Kappa | null | null | null | null | null |
4x7c | D | null | 0 | B | protein | null | vp1 | VIRAL PROTEIN | 12/09/14 | Crystal structure of Saga-2006 GII.4 P domain in complex with Nano-85 | NOROVIRUS HU/GII-4/SAGA1/2006/JP; VICUGNA PACOS | vicugna pacos | null | norovirus hu/gii-4/saga1/2006/jp | Koromyslova, A.D., Hansman, G.S. | 2.0 | X-RAY DIFFRACTION | 0.218 | 0.166 | false | true | IGHV1 | null | null | null | null | null | null | null |
5x0t | C | D | 0 | F | protein | null | basigin | IMMUNE SYSTEM | 01/23/17 | Crystal structure of CD147 C2 domain in complex with Fab of its monoclonal antibody 6H8 | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Lin, P., Zhang, M.-Y., Ye, S., Chen, X., Yu, X.-L., Zhang, R.-G., Zhu, P., Chen, Z.-N. | 2.5 | X-RAY DIFFRACTION | 0.300 | 0.246 | false | true | IGHV6 | IGKV6 | Kappa | null | null | null | null | null |
6edu | R | S | 0 | D | A | protein | protein | NA | NA | envelope glycoprotein gp160 | envelope glycoprotein gp160 | IMMUNE SYSTEM | 08/11/18 | B41 SOSIP.664 in complex with soluble CD4 (D1-D2), the co-receptor mimicking antibody 21c and the broadly neutralizing antibody 8ANC195 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | human immunodeficiency virus 1 | Barnes, C.O., Bjorkman, P.J. | 4.06 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
6mtr | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 10/21/18 | Crystal structure of VRC43.01 Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Kwon, Y.D., Druz, A., Law, W.H., Peng, D., Zhang, B., Doria-Rose, N.A., Kwong, P.D. | 1.798 | X-RAY DIFFRACTION | 0.243 | 0.209 | false | true | IGHV4 | IGLV7 | Lambda | null | null | null | null | null |
7a6e | C | B | 0 | A | protein | null | multidrug resistance protein 1 | TRANSPORT PROTEIN | 08/25/20 | Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and tariquidar | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Nosol, K., Locher, K.P. | 3.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
6mhg | K | V | 0 | E | protein | null | circumsporozoite protein | IMMUNE SYSTEM | 09/17/18 | Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts | PLASMODIUM FALCIPARUM; HOMO SAPIENS | homo sapiens | homo sapiens | plasmodium falciparum | Cottrell, C.A., Torres, J.L., Ward, A.B. | 3.57 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
1f3r | b | B | 0 | A | peptide | null | acetylcholine receptor alpha | IMMUNE SYSTEM | 06/06/00 | COMPLEX BETWEEN FV ANTIBODY FRAGMENT AND AN ANALOGUE OF THE MAIN IMMUNOGENIC REGION OF THE ACETYLCHOLINE RECEPTOR | RATTUS NORVEGICUS; SYNTHETIC CONSTRUCT | null | rattus norvegicus | null | Kleinjung, J., Petit, M.-C., Orlewski, P., Mamalaki, A., Tzartos, S.-J., Tsikaris, V., Sakarellos-Daitsiotis, M., Sakarellos, C., Marraud, M., Cung, M.-T. | NOT | SOLUTION NMR / HOMOLOGY MODEL | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
4qex | H | L | 0 | A | protein | null | erythrocyte-binding antigen-175 | IMMUNE SYSTEM | 05/19/14 | Crystal structure of PfEBA-175 RII in complex with a Fab fragment from inhibitory antibody R217 | PLASMODIUM FALCIPARUM; MUS MUSCULUS | mus musculus | mus musculus | plasmodium falciparum | Chen, E., Paing, M.M., Salinas, N., Sim, B.K., Tolia, N.H. | 4.5 | X-RAY DIFFRACTION | 0.285 | 0.232 | false | false | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7wcz | a | b | 0 | A | protein | null | heavy chain of s5d2 fab | VIRAL PROTEIN | 12/20/21 | SARS-CoV-2 Beta spike in complex with one S5D2 Fab | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; MUS MUSCULUS | mus musculus | mus musculus | severe acute respiratory syndrome coronavirus2 | Wang, Y.F., Cong, Y. | 3.5 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
3hr5 | I | P | 0 | T | peptide | null | m1prime-derived peptide | IMMUNE SYSTEM | 06/08/09 | M1prime peptide from IgE bound by humanized antibody 47H4 Fab | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Eigenbrot, C.W., Ultsch, M.H. | 2.4 | X-RAY DIFFRACTION | 0.253 | 0.213 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
2bx5 | null | D | 0 | null | null | null | null | ANTIBODY | 07/22/05 | Is FR1 the antibody's Achillies heel | ESCHERICHIA COLI | null | null | null | James, L.C. | 2.7 | X-RAY DIFFRACTION | 0.290 | 0.250 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
4r4b | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 08/19/14 | Crystal structure of the anti-hiv-1 antibody 2.2c | HOMO SAPIENS | homo sapiens | homo sapiens | null | McLellan, J.S., Acharya, P., Huang, C.-C., Robinson, J., Kwong, P.D. | 2.199 | X-RAY DIFFRACTION | 0.214 | 0.166 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
2qtj | B | M | 8 | null | null | null | null | IMMUNE SYSTEM | 08/02/07 | Solution structure of human dimeric immunoglobulin A | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Furtado, P.B., Almogren, A., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6ko5 | H | L | 0 | A | protein | null | chimera of soluble cytochrome b562 and growth hormonesecretagogue receptor type 1 | MEMBRANE PROTEIN | 08/08/19 | Complex structure of Ghrelin receptor with Fab | ESCHERICHIA COLI; HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | escherichia coli, homo sapiens | Shiimura, Y., Horita, S., Asada, H., Hirata, K., Iwata, S., Kojima, M. | 3.3 | X-RAY DIFFRACTION | 0.258 | 0.211 | false | false | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
7bnw | B | null | 0 | null | null | null | null | IMMUNE SYSTEM | 01/22/21 | Llama nanobody nb18 raised against GldL from Flavobacterium jonhsoniae | LAMA GLAMA | lama glama | null | null | Trinh, N.T., Cambillau, C., Leone, P. | 2.59 | X-RAY DIFFRACTION | 0.243 | 0.193 | false | true | IGHV1 | null | null | null | null | null | null | null |
7l06 | M | K | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 12/11/20 | Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound to two copies of domain-swapped antibody 2G12 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Manne, K., Henderson, R., Acharya, P. | 3.3 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
5n7b | H | h | 0 | I | peptide | null | apd(cg6)rp(nh2) peptide | IMMUNE SYSTEM | 02/20/17 | Understanding the singular conformational landscape of the Tn antigens: Sulfur-for- oxygen substitution in the glycosidic linkage provides new insights into molecular recognition by an antibody | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | null | synthetic construct | Companon, I., Martinez-Saez, N., Castro-Lopez, J., Jimenez-Barbero, J., Bernardes, G.J.L., Busto, J.H., Avenoza, A., Jimenez-Oses, G., Hurtado-Guerrero, R., Peregrina, J.M., Corzana, F. | 1.7 | X-RAY DIFFRACTION | 0.211 | 0.176 | true | true | unknown | unknown | unknown | null | null | null | null | null |
7zr9 | H | L | 0 | A | protein | null | spike glycoprotein,fibritin | STRUCTURAL PROTEIN | 05/03/22 | OMI-2 FAB IN COMPLEX WITH SARS-COV-2 BETA SPIKE GLYCOPROTEIN | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; ENTEROBACTERIA PHAGE T4; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2, enterobacteria phage t4 | Duyvesteyn, H.M.E., Ren, J., Stuart, D.I. | 4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
3skj | I | M | 0 | F | protein | null | ephrin type-a receptor 2 | IMMUNE SYSTEM | 06/22/11 | Structural And Functional Characterization of an Agonistic Anti-Human EphA2 Monoclonal Antibody | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Oganesyan, V.Y., Wu, H., Dall'Acqua, W.F. | 2.5 | X-RAY DIFFRACTION | 0.271 | 0.216 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -12.4 | SPR | null | 21867711 |
3qg6 | H | L | 0 | C | peptide | null | agr autoinducing peptide | IMMUNE SYSTEM/INHIBITOR | 01/24/11 | Structural Basis for Ligand Recognition and Discrimination of a Quorum Quenching Antibody | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Kirchdoerfer, R.N., Janda, J.D., Kaufmann, G.F, Wilson, I.A | 2.5 | X-RAY DIFFRACTION | 0.239 | 0.184 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4lsq | H | L | 0 | G | protein | null | envelope glycoprotein gp120 with loop d and v5 from strain3415_v1_c1 | viral protein/immune system | 07/23/13 | Crystal structure of broadly and potently neutralizing antibody VRC-CH31 in complex with HIV-1 clade A/E gp120 93TH057 with LOOP D and Loop V5 from clade A strain 3415_v1_c1 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Zhou, T., Moquin, S., Kwong, P.D. | 2.25 | X-RAY DIFFRACTION | 0.229 | 0.192 | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
7a0v | F | null | 0 | E | protein | null | synaptojanin-1 | HYDROLASE | 08/11/20 | Crystal structure of the 5-phosphatase domain of Synaptojanin1 in complex with a nanobody | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Paesmans, J., Galicia, C., Martin, E., Versees, W. | 2.3 | X-RAY DIFFRACTION | 0.252 | 0.196 | false | true | IGHV1 | null | null | null | null | null | null | null |
7wd9 | I | J | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN | 12/21/21 | SARS-CoV-2 Beta spike in complex with three S3H3 Fabs | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; MUS MUSCULUS | mus musculus | mus musculus | severe acute respiratory syndrome coronavirus2 | Wang, Y.F., Cong, Y. | 3.7 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7mdw | B | null | 0 | R | protein | null | spike protein s1 | VIRAL PROTEIN/Immune System | 04/06/21 | CryoEM structure of SARS-CoV-2 RBD in complex with nanobodies Nb21 and Nb105 | LAMA GLAMA; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | lama glama | null | severe acute respiratory syndrome coronavirus2 | Huang, W., Taylor, D.J. | 3.58 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
6xli | H | L | 0 | P | peptide | null | tau phosphopeptide (ac-sr(pt)pslp(pt)pptre-oh) | IMMUNE SYSTEM | 06/28/20 | CRYSTAL STRUCTURE OF ANTI-TAU ANTIBODY PT3 Fab+pT212/pT217-TAU PEPTIDE | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Malia, T.J., Teplyakov, A., Luo, J. | 2.0 | X-RAY DIFFRACTION | 0.213 | 0.186 | false | true | IGHV5 | IGKV14 | Kappa | null | null | null | null | null |
5dhz | H | L | 0 | M | protein | null | protein rev | IMMUNE SYSTEM | 08/31/15 | HIV-1 Rev NTD dimers with variable crossing angles | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | DiMattia, M.A., Watts, N.R., Wingfield, P.T., Grimes, J.M., Stuart, D.I., Steven, A.C. | 4.3 | X-RAY DIFFRACTION | unknown | unknown | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6rps | H | L | 0 | A | protein | null | carbonic anhydrase 12 | LYASE | 05/14/19 | X-ray crystal structure of carbonic anhydrase XII complexed with a theranostic monoclonal antibody fragment | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Alterio, V., Esposito, D., De Simone, G. | 2.79 | X-RAY DIFFRACTION | 0.231 | 0.203 | false | true | IGHV2 | IGKV5 | Kappa | null | null | null | null | null |
6r7t | A | null | 0 | B | protein | null | melanoma-associated antigen b1 | IMMUNE SYSTEM | 03/29/19 | Crystal Structure of human Melanoma-associated antigen B1 (MAGEB1) in complex with nanobody | LAMA GLAMA; HOMO SAPIENS | lama glama | null | homo sapiens | Ye, M., Newman, J., Pike, A.C.W., Burgess-Brown, N., Bountra, C., Arrowsmith, C., Edwards, A., Gileadi, O., von Delft, F. | 2.682 | X-RAY DIFFRACTION | 0.288 | 0.258 | false | true | IGHV3 | null | null | null | null | null | null | null |
1ymh | B | A | 0 | E | protein | null | protein l | IMMUNE SYSTEM | 01/21/05 | anti-HCV Fab 19D9D6 complexed with protein L (PpL) mutant A66W | FINEGOLDIA MAGNA; MUS MUSCULUS | mus musculus | mus musculus | finegoldia magna | Granata, V., Housden, N.G., Harrison, S., Jolivet-Reynaud, C., Gore, M.G., Stura, E.A. | 2.6 | X-RAY DIFFRACTION | 0.302 | 0.224 | false | false | IGHV9 | IGKV8 | Kappa | null | null | null | null | null |
2mmx | null | A | 8 | null | null | null | null | IMMUNE SYSTEM | 03/20/14 | NMR study of 6aJL2 | HOMO SAPIENS | null | homo sapiens | null | Amero, C., Maya-Martinez, R.C., Gil-Rodriguez, P.C. | NOT | SOLUTION NMR | null | null | false | true | null | IGLV6 | Lambda | null | null | null | null | null |
6xul | H | L | 0 | null | null | null | null | ANTITUMOR PROTEIN | 01/20/20 | Apo Ab 5b1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Diskin, R., Borenstein-Katz, A. | 2.41 | X-RAY DIFFRACTION | 0.230 | 0.168 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
7rd4 | H | L | 0 | G | peptide | null | circumsporozoite protein | IMMUNE SYSTEM | 07/09/21 | Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.149 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | plasmodium falciparum | Xu, K., Kwong, P.D. | 1.75 | X-RAY DIFFRACTION | 0.233 | 0.194 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
1xf4 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 09/13/04 | Structure of ligand-free Fab DNA-1 in space group P321 solved from crystals with perfect hemihedral twinning | MUS MUSCULUS | mus musculus | mus musculus | null | Schuermann, J.P., Prewitt, S.P., Deutscher, S.L., Tanner, J.J. | 2.5 | X-RAY DIFFRACTION | 0.224 | 0.183 | false | true | IGHV1 | IGKV12 | Kappa | null | null | null | null | null |
4r4b | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 08/19/14 | Crystal structure of the anti-hiv-1 antibody 2.2c | HOMO SAPIENS | homo sapiens | homo sapiens | null | McLellan, J.S., Acharya, P., Huang, C.-C., Robinson, J., Kwong, P.D. | 2.199 | X-RAY DIFFRACTION | 0.214 | 0.166 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
1yec | H | L | 0 | H | Hapten | PNB | 4-NITRO-BENZYLPHOSPHONOBUTANOYL-GLYCINE | CATALYTIC ANTIBODY | 04/15/97 | STRUCTURE OF A CATALYTIC ANTIBODY IGG2A FAB FRAGMENT (D2.3) | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Golinelli-Pimpaneau, B., Knossow, M. | 1.9 | X-RAY DIFFRACTION | 0.252 | 0.208 | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5grv | L | K | 0 | null | null | null | null | IMMUNE SYSTEM | 08/12/16 | Crystal structure of homo-specific diabody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Kim, J.H., Song, D.H., Youn, S.J., Kim, J.W., Cho, G., Lee, H., Lee, J.O. | 2.3 | X-RAY DIFFRACTION | 0.221 | 0.184 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
3whe | 3 | 4 | 0 | I | protein | null | hemagglutinin | VIRAL PROTEIN/IMMUNE SYSTEM | 08/25/13 | A new conserved neutralizing epitope at the globular head of hemagglutinin in H3N2 influenza viruses | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus | Fujii, Y., Sumida, T., Shirouzu, M., Yokoyama, S. | 4.0 | X-RAY DIFFRACTION | 0.308 | 0.235 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
5m2i | L | null | 0 | F | protein | null | tumor necrosis factor | CYTOKINE | 10/13/16 | Structure of human Tumor Necrosis Factor (TNF) in complex with the Llama VHH1 | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Cambillau, C., Spinelli, S., Desmyter, A., de Haard, H. | 2.15 | X-RAY DIFFRACTION | 0.238 | 0.207 | false | true | IGHV1 | null | null | 0 | -12.643277 | SPR | null | TBD |
4tvs | a | null | 0 | A | protein | null | vhh domain bs-1 | MEMBRANE PROTEIN | 06/27/14 | LAP1(aa356-583), H.sapiens, bound to VHH-BS1 | HOMO SAPIENS; VICUGNA PACOS | vicugna pacos | null | homo sapiens | Sosa, B.A., Schwartz, T.U. | 1.6 | X-RAY DIFFRACTION | 0.229 | 0.181 | false | false | IGHV1 | null | null | null | null | null | null | null |
6oyz | G | null | 0 | C | protein | null | phospho-n-acetylmuramoyl-pentapeptide-transferase | MEMBRANE PROTEIN/TRANSFERASE | 05/15/19 | Crystal structure of MraY bound to capuramycin | LAMA GLAMA; AQUIFEX AEOLICUS (STRAIN VF5) | lama glama | null | aquifex aeolicus (strain vf5) | Mashalidis, E.H., Lee, S.Y. | 3.62 | X-RAY DIFFRACTION | 0.301 | 0.277 | false | true | IGHV1 | null | null | null | null | null | null | null |
4xnm | H | L | 0 | C | protein | null | hemagglutinin | Viral protein/Immune system | 01/15/15 | Antibody Influenza H5 Complex | HOMO SAPIENS; INFLUENZA A VIRUS | homo sapiens | homo sapiens | influenza a virus | Winarski, K.L., Spiler, B.W. | 2.51 | X-RAY DIFFRACTION | 0.241 | 0.214 | false | true | IGHV4 | IGLV3 | Lambda | 0 | -11.046162 | SPR | null | TBD |
5m2i | I | null | 0 | C | protein | null | tumor necrosis factor | CYTOKINE | 10/13/16 | Structure of human Tumor Necrosis Factor (TNF) in complex with the Llama VHH1 | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Cambillau, C., Spinelli, S., Desmyter, A., de Haard, H. | 2.15 | X-RAY DIFFRACTION | 0.238 | 0.207 | false | true | IGHV1 | null | null | 0 | -12.643277 | SPR | null | TBD |
4pd4 | J | K | 0 | E | protein | null | cytochrome b-c1 complex subunit rieske, mitochondrial | OXIDOREDUCTASE/INHIBITOR | 04/17/14 | Structural analysis of atovaquone-inhibited cytochrome bc1 complex reveals the molecular basis of antimalarial drug action | MUS MUSCULUS; SACCHAROMYCES CEREVISIAE | mus musculus | mus musculus | saccharomyces cerevisiae | Birth, D., Kao, W.-C., Hunte, C. | 3.04 | X-RAY DIFFRACTION | 0.297 | 0.268 | false | true | IGHV3 | IGKV10 | Kappa | null | null | null | null | null |
2ghw | D | d | 0 | C | protein | null | spike glycoprotein | VIRUS/VIRAL PROTEIN/ANTIBIOTIC | 03/27/06 | Crystal structure of SARS spike protein receptor binding domain in complex with a neutralizing antibody, 80R | SARS CORONAVIRUS; HOMO SAPIENS | homo sapiens | null | sars coronavirus | Hwang, W.C., Lin, Y., Santelli, E., Sui, J., Jaroszewski, L., Stec, B., Farzan, M., Marasco, W.A., Liddington, R.C. | 2.3 | X-RAY DIFFRACTION | 0.295 | 0.248 | true | true | unknown | unknown | unknown | null | null | null | null | null |
6ur5 | G | H | 0 | D | protein | null | influenza hemagglutinin ha1 | VIRAL PROTEIN/IMMUNE SYSTEM | 06/10/20 | Resurfaced influenza hemagglutinin in complex with a broadly neutralizing antibody | HOMO SAPIENS; INFLUENZA A VIRUS | homo sapiens | homo sapiens | influenza a virus | Bajic, G., Schmidt, A.G. | 4.0 | X-RAY DIFFRACTION | 0.322 | 0.300 | false | true | IGHV1 | IGLV2 | Lambda | null | null | null | null | null |
4tuj | C | D | 0 | F | peptide | null | peptide1 | IMMUNE SYSTEM | 06/24/14 | Crystal structure of monoclonal antibody against neuroblastoma associated antigen. | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Grudnik, P., Golik, P., Horwacik, I., Zdzalik, M., Rokita, H., Dubin, G. | 1.89 | X-RAY DIFFRACTION | 0.232 | 0.179 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
2mmx | null | A | 18 | null | null | null | null | IMMUNE SYSTEM | 03/20/14 | NMR study of 6aJL2 | HOMO SAPIENS | null | homo sapiens | null | Amero, C., Maya-Martinez, R.C., Gil-Rodriguez, P.C. | NOT | SOLUTION NMR | null | null | false | true | null | IGLV6 | Lambda | null | null | null | null | null |
6zhd | F | null | 0 | B | protein | null | spike glycoprotein,fibritin | ANTIVIRAL PROTEIN | 06/22/20 | H11-H4 bound to Spike | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; ENTEROBACTERIA PHAGE T4; LAMA GLAMA | lama glama | null | severe acute respiratory syndrome coronavirus2, enterobacteria phage t4 | Clare, D.K., Naismith, J.H., Weckener, M., Vogirala, V.K. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
4web | H | L | 0 | E | protein | null | hepatitis c virus envelope glycoprotein 2 | IMMUNE SYSTEM/VIRAL PROTEIN | 09/09/14 | Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2 | HEPATITIS C VIRUS SUBTYPE 2A; MUS MUSCULUS | mus musculus | mus musculus | hepatitis c virus subtype 2a | Khan, A.G., Whidby, J., Miller, M.T., Scarborough, H., Zatorski, A.V., Cygan, A., Price, A.A., Yost, S.A., Bohannon, C.D., Jacob, J., Grakoui, A., Marcotrigiano, J. | 2.4 | X-RAY DIFFRACTION | 0.259 | 0.199 | false | true | IGHV14 | IGKV8 | Kappa | null | null | null | null | null |
3csy | A | B | 0 | J | I | protein | protein | NA | NA | envelope glycoprotein gp2 | envelope glycoprotein gp1 | IMMUNE SYSTEM/VIRAL PROTEIN | 04/10/08 | Crystal structure of the trimeric prefusion Ebola virus glycoprotein in complex with a neutralizing antibody from a human survivor | HOMO SAPIENS; ZAIRE EBOLA VIRUS | homo sapiens | homo sapiens | zaire ebola virus | zaire ebola virus | Lee, J.E., Fusco, M.L., Hessell, A.J., Oswald, W.B., Burton, D.R., Saphire, E.O. | 3.4 | X-RAY DIFFRACTION | 0.302 | 0.261 | false | true | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
5t6l | H | L | 0 | I | protein | null | 10e8 epitope scaffold t117v2 | IMMUNE SYSTEM | 09/01/16 | Crystal structure of 10E8 Fab in complex with the MPER epitope scaffold T117v2 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | synthetic construct | Irimia, A., Wilson, I.A. | 2.1 | X-RAY DIFFRACTION | 0.218 | 0.178 | false | true | IGHV3 | IGLV3 | Lambda | 0 | -14.386166 | SPR | null | TBD |
7ntc | H | L | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN | 03/09/21 | Trimeric SARS-CoV-2 spike ectodomain bound to P008_056 Fab | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Rosa, A., Pye, V.E., Nans, A., Cherepanov, P. | 3.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6o25 | E | F | 0 | H | peptide | null | circumsporozoite protein | IMMUNE SYSTEM | 02/22/19 | Crystal structure of 3945 Fab in complex with circumsporozoite protein NANP3 and anti-Kappa VHH domain | HOMO SAPIENS; LAMA GLAMA; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | plasmodium falciparum | Scally, S.W., Bosch, A., Prieto, K., Murugan, R., Wardemann, H., Julien, J.P. | 2.9 | X-RAY DIFFRACTION | 0.268 | 0.215 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
6mu6 | D | E | 0 | B | protein | null | envelope glycoprotein gp160 | IMMUNE SYSTEM/INHIBITOR | 10/22/18 | Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to Small Molecule HIV-1 Entry Inhibitor BMS-814508 in Complex with Human Antibodies 3H109L and 35O22 at 3.2 Angstrom | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Lai, Y.-T., Kwong, P.D. | 2.551 | X-RAY DIFFRACTION | 0.264 | 0.231 | false | true | unknown | unknown | unknown | null | null | null | null | null |
6huk | G | null | 0 | A | E | protein | protein | NA | NA | gamma-aminobutyric acid receptor subunit alpha-1,gamma-aminobutyric acid receptor subunit alpha-1 | gamma-aminobutyric acid receptor subunit beta-3 | MEMBRANE PROTEIN | 10/08/18 | CryoEM structure of human full-length alpha1beta3gamma2L GABA(A)R in complex with bicuculline and megabody Mb38. | BOS TAURUS; HOMO SAPIENS; LAMA GLAMA | lama glama | null | bos taurus, homo sapiens | homo sapiens | Masiulis, S., Desai, R., Uchanski, T., Serna Martin, I., Laverty, D., Karia, D., Malinauskas, T., Jasenko, Z., Pardon, E., Kotecha, A., Steyaert, J., Miller, K.W., Aricescu, A.R. | 3.69 | ELECTRON MICROSCOPY | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
6nc2 | Q | V | 0 | K | E | protein | protein | NA | NA | amc011 v4.2 sosip gp41 | amc011 v4.2 sosip gp120 | IMMUNE SYSTEM | 12/10/18 | AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody ACS202 fragment antigen binding | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | human immunodeficiency virus 1 | Cottrell, C.A., Ozorowski, G., Yuan, M., Copps, J., Wilson, I.A., Ward, A.B. | 5.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6vi1 | F | C | 0 | O | peptide | null | terminase, large subunit | IMMUNE SYSTEM | 01/11/20 | Structure of Fab4 bound to P22 TerL(1-33) | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | salmonella phage p22 | Cingolani, G., Lokareddy, R., Ko, Y. | 2.4 | X-RAY DIFFRACTION | 0.239 | 0.189 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
1mce | null | B | 0 | P | peptide | null | peptide n-acetyl-l-gln-d-phe-l-his-d-pro-b-ala-oh | IMMUNOGLOBULIN | 02/25/93 | PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS | HOMO SAPIENS | null | homo sapiens | null | Edmundson, A.B., Harris, D.L., Fan, Z.-C., Guddat, L.W. | 2.7 | X-RAY DIFFRACTION | unknown | unknown | false | true | null | IGLV2 | Lambda | null | null | null | null | null |
7k75 | M | N | 0 | E | peptide | null | pfcsp n-terminal peptide p17 | IMMUNE SYSTEM | 09/22/20 | Crystal structure of MAD2-6 IgA Fab in complex with PfCSP N-terminal peptide. | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | plasmodium falciparum | Pholcharee, T., Wilson, I.A. | 2.5 | X-RAY DIFFRACTION | 0.236 | 0.192 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
7k60 | N | n | 0 | G | F | H | protein | protein | protein | NA | NA | NA | histone h2a type 1-b/e | histone h4 | histone h2b type 1-j | NUCLEAR PROTEIN/DNA | 09/17/20 | Cryo-EM structure of a chromatosome containing human linker histone H1.10 | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | homo sapiens | homo sapiens | Zhou, B.-R., Bai, Y. | 3.12 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
6mqm | J | K | 0 | L | peptide | null | hiv env fusion peptide residue 512-519 | IMMUNE SYSTEM | 10/10/18 | Vaccine-elicited NHP FP-targeting neutralizing antibody DF1W-a.01 in complex with HIV fusion peptide (residue 512-519) | PLATYRRHINI; SYNTHETIC CONSTRUCT | platyrrhini | platyrrhini | human immunodeficiency virus 1 | Xu, K., Wang, Y., Kwong, P.D. | 3.484 | X-RAY DIFFRACTION | 0.246 | 0.200 | false | true | IGHV4 | IGKV2 | Kappa | null | null | null | null | null |
5t5n | K | J | 0 | B | protein | null | bestrophin-1 (best1) | MEMBRANE PROTEIN | 08/31/16 | Calcium-activated chloride channel bestrophin-1 (BEST1), triple mutant: I76A, F80A, F84A; in complex with an Fab antibody fragment, chloride, and calcium | GALLUS GALLUS; MUS MUSCULUS | mus musculus | mus musculus | gallus gallus | Long, S.B., Vaisey, G. | 3.1 | X-RAY DIFFRACTION | 0.243 | 0.218 | false | false | IGHV1 | IGKV12 | Kappa | null | null | null | null | null |
7rdl | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 07/09/21 | Crystal structure of PCDN-22A, an anti-HIV antibody from the PCDN bnAb lineage | HOMO SAPIENS | homo sapiens | homo sapiens | null | Omorodion, O., Wilson, I.A. | 2.71 | X-RAY DIFFRACTION | 0.258 | 0.230 | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
5any | L | P | 0 | H | G | protein | protein | NA | NA | e2 | e1 | VIRUS | 09/08/15 | Electron cryo-microscopy of chikungunya virus in complex with neutralizing antibody Fab CHK265 | CHIKUNGUNYA VIRUS; MUS MUSCULUS | mus musculus | mus musculus | chikungunya virus | chikungunya virus | Fox, J.M., Long, F., Edeling, M.A., Lin, H., Duijl-Richter, M., Fong, R.H., Kahle, K.M., Smit, J.M., Jin, J., Simmons, G., Doranz, B.J., Crowe, J.E., Fremont, D.H., Rossmann, M.G., Diamond, M.S. | 16.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV9 | IGLV1 | Lambda | null | null | null | null | null |
6aj9 | H | L | 0 | C | B | protein | protein | NA | NA | capsid protein vp3 | capsid protein vp2 | VIRUS | 08/27/18 | The structure of Enterovirus D68 mature virion in complex with Fab 15C5 and 11G1 | MUS MUSCULUS; ENTEROVIRUS D68 | mus musculus | mus musculus | enterovirus d68 | enterovirus d68 | Zheng, Q.B., Zhu, R., Xu, L.F., He, M.Z., Yan, X.D., Cheng, T., Li, S.W. | 3.5 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV9 | Kappa | null | null | null | null | null |
2qtj | C | O | 6 | null | null | null | null | IMMUNE SYSTEM | 08/02/07 | Solution structure of human dimeric immunoglobulin A | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Furtado, P.B., Almogren, A., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7s6k | C | D | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN/Immune System | 09/14/21 | J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut2 S protein (conformation 2) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Ozorowski, G., Torres, J.L., Ward, A.B. | 3.4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
3j8w | I | M | 0 | B | A | protein | protein | NA | NA | l1 | l1 | VIRUS/IMMUNE SYSTEM | 11/19/14 | Cryo-EM reconstruction of quasi-HPV16 complex with H263.A2 Fab | MUS MUSCULUS; HUMAN PAPILLOMAVIRUS TYPE 16 | mus musculus | mus musculus | human papillomavirus type 16 | human papillomavirus type 16 | Guan, J., Hafenstein, S. | 13 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV12 | Kappa | null | null | null | null | null |
5hvh | C | null | 0 | A | protein | null | carboxypeptidase b2 | HYDROLASE/HYDROLASE INHIBITOR | 01/28/16 | Crystal Structure of Thrombin-activatable Fibrinolysis Inhibitor in Complex with two Inhibitory Nanobodies | HOMO SAPIENS; VICUGNA PACOS | vicugna pacos | null | homo sapiens | Zhou, X., Weeks, S.D., Strelkov, S.V., Declerck, P.J. | 3.0 | X-RAY DIFFRACTION | 0.202 | 0.190 | false | true | IGHV1 | null | null | null | null | null | null | null |
6avn | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 09/03/17 | Crystal structure of unbound anti-HIV antibody Fab PGV19 at 2.5 A | HOMO SAPIENS | homo sapiens | homo sapiens | null | Sarkar, A., Wilson, I.A. | 2.5 | X-RAY DIFFRACTION | 0.250 | 0.199 | false | true | unknown | IGLV2 | Lambda | null | null | null | null | null |
1mck | null | B | 0 | P | peptide | null | peptide n-acetyl-d-glu-l-his-d-pro-nh2 | IMMUNOGLOBULIN | 02/25/93 | PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS | HOMO SAPIENS | null | homo sapiens | null | Edmundson, A.B., Harris, D.L., Fan, Z.-C., Guddat, L.W. | 2.7 | X-RAY DIFFRACTION | unknown | unknown | false | true | null | IGLV2 | Lambda | null | null | null | null | null |
1ieh | A | null | 6 | null | null | null | null | IMMUNE SYSTEM | 04/09/01 | SOLUTION STRUCTURE OF A SOLUBLE SINGLE-DOMAIN ANTIBODY WITH HYDROPHOBIC RESIDUES TYPICAL OF A VL/VH INTERFACE | LAMA GLAMA | lama glama | null | null | Vranken, W., Tolkatchev, D., Xu, P., Tanha, J., Chen, Z., Narang, S., Ni, F. | NOT | SOLUTION NMR | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
3chn | C | O | 9 | null | null | null | null | IMMUNE SYSTEM | 03/10/08 | Solution structure of human secretory IgA1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Almogren, A., Furtado, P.B., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING / HOMOLOGY MODEL | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
3s88 | H | L | 0 | J | J | I | carbohydrate | protein | protein | NAG | NA | NA | N-ACETYL-D-GLUCOSAMINE | envelope glycoprotein | envelope glycoprotein | IMMUNE SYSTEM/VIRAL PROTEIN | 05/27/11 | Crystal structure of Sudan Ebolavirus Glycoprotein (strain Gulu) bound to 16F6 | MUS MUSCULUS; SUDAN EBOLAVIRUS | mus musculus | mus musculus | sudan ebolavirus | sudan ebolavirus | sudan ebolavirus | Saphire, E.O., Dias, J.M., Bale, S. | 3.351 | X-RAY DIFFRACTION | 0.278 | 0.222 | false | true | IGHV5 | IGKV6 | Kappa | null | null | null | null | null |
3cm9 | D | O | 7 | null | null | null | null | IMMUNE SYSTEM | 03/21/08 | Solution Structure of Human SIgA2 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Almogren, A., Furtado, P.B., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7n5h | E | F | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 06/05/21 | Cryo-EM structure of broadly neutralizing antibody 2-36 in complex with prefusion SARS-CoV-2 spike glycoprotein | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Casner, R.G., Cerutti, G., Shapiro, L. | 3.24 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
4uok | A | L | 0 | null | null | null | null | IMMUNE SYSTEM | 06/04/14 | Electron Cryo-microscopy of Venezuelan Equine Encephalitis Virus TC-83 in complex with neutralizing antibody Fab 3B4C-4 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Porta, J., Jose, J., Roehrig, J.T., Blair, C.D., Kuhn, R.J., G Rossmann, M. | 18.0 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
4lsu | H | L | 0 | G | protein | null | hiv-1 clade a/e strain 93th057 gp120 | viral protein/immune system | 07/23/13 | Crystal structure of broadly and potently neutralizing antibody VRC-PG20 in complex with HIV-1 clade A/E 93TH057 gp120 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Zhou, T., Moquin, S., Kwong, P.D. | 2.3 | X-RAY DIFFRACTION | 0.234 | 0.179 | false | true | IGHV1 | IGLV2 | Lambda | null | null | null | null | null |
6wzm | A | B | 0 | E | protein | null | interleukin-8 | IMMUNE SYSTEM | 05/14/20 | LY3041658 Fab bound to CXCL8 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Durbin, J.D., Druzina, Z. | 2.28 | X-RAY DIFFRACTION | 0.229 | 0.187 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5m63 | M | N | 0 | N | carbohydrate | GAL | polysaccharide | IMMUNE SYSTEM | 10/24/16 | Crystal structure of group B Streptococcus type III DP2 oligosaccharide bound to Fab NVS-1-19-5 | ORYCTOLAGUS CUNICULUS | oryctolagus cuniculus | oryctolagus cuniculus | oryctolagus cuniculus | Carboni, F., Adamo, R., Veggi, D., Rappuoli, R., Malito, E., Margarit, I.R., Berti, F. | 2.74 | X-RAY DIFFRACTION | 0.282 | 0.236 | false | true | IGHV1 | IGKV1 | Kappa | 0 | -9.493239 | Unknown | null | TBD |
5c2b | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 06/15/15 | anti-CXCL13 parental scFv - 3B4 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Tu, C., Bard, J., Mosyak, L. | 1.4049 | X-RAY DIFFRACTION | 0.194 | 0.179 | true | true | IGHV1 | IGLV2 | Lambda | null | null | null | null | null |
6ofi | H | L | 0 | G | protein | null | clade a/e 93th057 hiv-1 gp120 core | IMMUNE SYSTEM | 03/29/19 | CRYSTAL STRUCTURE OF the RV144 C1-C2 SPECIFIC ANTIBODY CH55 FAB IN COMPLEX WITH HIV-1 CLADE A/E GP120 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Tolbert, W.D., Yan, F., Van, V., Pazgier, M. | 3.85 | X-RAY DIFFRACTION | 0.326 | 0.271 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5bk3 | E | F | 0 | F | carbohydrate | NAG | polysaccharide | IMMUNE SYSTEM | 09/12/17 | Crystal structure of the neutralizing anti-circumsporozoite protein 580 antibody | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Scally, S.W., Bosch, A., Triller, G., Wardemann, H., Julien, J.P. | 2.8 | X-RAY DIFFRACTION | 0.231 | 0.190 | false | true | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
4yk4 | Z | Y | 0 | E | protein | null | hemagglutinin | Viral protein/Immune system | 03/03/15 | Human antibody 641 I-9 in complex with influenza hemagglutinin H1 Solomon Islands/03/2006 | HOMO SAPIENS; INFLUENZA A VIRUS | homo sapiens | homo sapiens | influenza a virus | Schmidt, A.G., Harrison, S.C. | 2.8 | X-RAY DIFFRACTION | 0.260 | 0.220 | false | true | IGHV4 | IGKV1 | Kappa | 0 | -8.784229 | BLI | null | TBD |
6h6y | G | null | 0 | C | protein | null | capsid protein vp1 | VIRAL PROTEIN | 12/19/18 | GI.1 human norovirus protruding domain in complex with Nano-7 | NORWALK VIRUS (STRAIN GI/HUMAN/UNITED STATES/NORWALK/1968); VICUGNA PACOS | vicugna pacos | null | norwalk virus (strain gi/human/unitedstates/norwalk/1968) | Kilic, T., Ruoff, K., Hansman, G.S. | 1.58 | X-RAY DIFFRACTION | 0.175 | 0.155 | false | true | IGHV1 | null | null | null | null | null | null | null |
5iie | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 03/01/16 | STRUCTURE OF THE UNLIGANDED ANTI-HIV ANTIBODY DH501 THAT BINDS GP120 V3 GLYCAN AND THE BASE OF V3 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Nicely, N.I., Haynes, B.F. | 2.8 | X-RAY DIFFRACTION | 0.273 | 0.206 | false | true | IGHV2 | IGLV1 | Lambda | null | null | null | null | null |
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