pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
6o2b | O | P | 0 | L | M | peptide | protein | NA | NA | circumsporozoite protein | anti-kappa vhh domain | IMMUNE SYSTEM | 02/22/19 | Crystal structure of 4493 Fab in complex with circumsporozoite protein DND and anti-kappa VHH domain | HOMO SAPIENS; LAMA GLAMA; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | plasmodium falciparum | lama glama | Scally, S.W., Bosch, A., Prieto, K., Murugan, R., Wardemann, H., Julien, J.P. | 2.1 | X-RAY DIFFRACTION | 0.210 | 0.177 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
2ny0 | D | C | 0 | A | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 11/20/06 | HIV-1 gp120 Envelope Glycoprotein (M95W, W96C, T257S, V275C, S334A, S375W, A433M) Complexed with CD4 and Antibody 17b | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D. | 2.2 | X-RAY DIFFRACTION | 0.242 | 0.202 | false | true | IGHV1 | IGKV3 | Kappa | 0 | null | SPR | null | 17301785 |
7rlw | C | D | 0 | R | peptide | null | pvcspvk210 peptide from circumsporozoite protein | ANTIMICROBIAL PROTEIN | 07/26/21 | Antibody 2F2 in complex with P. vivax CSP peptide GDRAAGQPAGDRAAGQPA | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | plasmodium vivax | Kucharska, I., Julien, J.P. | 2.54 | X-RAY DIFFRACTION | 0.253 | 0.201 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6vi0 | H | L | 0 | G | protein | null | bg505 gp120 | IMMUNE SYSTEM | 01/10/20 | Cryo-EM structure of VRC01.23 in complex with HIV-1 Env BG505 DS.SOSIP | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Gorman, J., Kwong, P.D. | 3.43 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV3 | Kappa | null | null | null | null | null |
6idk | H | L | 0 | D | protein | null | premembrane protein | VIRUS | 09/10/18 | Cryo-EM structure of Immature Dengue virus serotype 3 in complex with human antibody 1H10 Fab at pH 5.0 (Class I particle) | DENGUE VIRUS 3; HOMO SAPIENS | homo sapiens | homo sapiens | dengue virus 3 | Wirawan, M., Fibriansah, G., Ng, T.S., Zhang, Q., Kostyuchenko, V.A., Shi, J., Lok, S.M. | 25 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
7kxk | I | M | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN/Immune System | 12/04/20 | SARS-CoV-2 spike protein in complex with Fab 15033-7, 2-""up""-1-""down"" conformation | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Li, Z., Rini, J. | 5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
1moe | B | b | 0 | null | null | null | null | IMMUNE SYSTEM | 09/09/02 | The three-dimensional structure of an engineered scFv T84.66 dimer or diabody in VL to VH linkage. | MUS MUSCULUS | mus musculus | null | null | Carmichael, J.A., Power, B.E., Garrett, T.P.J., Yazaki, P.J., Shively, J.E., Raubischek, A.A., Wu, A.M., Hudson, P.J. | 2.6 | X-RAY DIFFRACTION | 0.300 | 0.213 | true | true | unknown | unknown | unknown | null | null | null | null | null |
2gfb | L | K | 0 | null | null | null | null | IMMUNOGLOBULIN | 07/07/94 | CRYSTAL STRUCTURE OF A CATALYTIC FAB HAVING ESTERASE-LIKE ACTIVITY | MUS MUSCULUS | mus musculus | mus musculus | null | Golinelli-Pimpaneau, B., Knossow, M. | 3.0 | X-RAY DIFFRACTION | unknown | 0.213 | false | false | IGHV5 | IGKV9 | Kappa | null | null | null | null | null |
6myy | G | F | 0 | E | protein | null | 426c ds-sosip d3 | VIRAL PROTEIN/IMMUNE SYSTEM | 11/02/18 | Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 3 Fabs bound, sharpened map | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Borst, A.J., Weidle, C.E., Gray, M.D., Frenz, B., Snijder, J., Joyce, M.G., Georgiev, I.S., Stewart-Jones, G.B.E., Kwong, P.D., McGuire, A.T., DiMaio, F., Stamatatos, L., Pancera, M., Veesler, D. | 3.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7t4r | P | Q | 0 | K | protein | null | envelope glycoprotein h | VIRAL PROTEIN/Immune System | 12/10/21 | CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with THBD and neutralizing fabs MSL-109 and 13H11 | HOMO SAPIENS; HUMAN BETAHERPESVIRUS 5 | homo sapiens | homo sapiens | human betaherpesvirus 5 | Kschonsak, M., Johnson, M.C., Schelling, R., Green, E.M., Rouge, L., Ho, H., Patel, N., Kilic, C., Kraft, E., Arthur, C.P., Rohou, A.L., Comps-Agrar, L., Martinez-Martin, N., Perez, L., Payandeh, J., Ciferri, C. | 3.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6wf1 | H | L | 0 | B | A | protein | protein | NA | NA | hemagglutinin ha2 chain | hemagglutinin | VIRAL PROTEIN/Immune System | 04/03/20 | Crystal Structure of Broadly Neutralizing Antibody 3I14 Bound to the Influenza A H10 Hemagglutinin | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus | influenza a virus | Harshbarger, W.D., Lockbaum, G.J., Deming, D.T., Attatippaholkun, N., Schiffer, C.A., Marasco, W.A. | 4.19 | X-RAY DIFFRACTION | 0.309 | 0.261 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
6xox | E | e | 0 | A | protein | null | alpha subunit of gs with n-terminus swapped with equivalentresidues in gi,guanine nucleotide-binding protein g(s) subunit alpha isoforms xlas | MEMBRANE PROTEIN | 07/07/20 | cryo-EM of human GLP-1R bound to non-peptide agonist LY3502970 | HOMO SAPIENS; MUS MUSCULUS; LAMA GLAMA | mus musculus | null | homo sapiens | Sun, B., Kobilka, B.K., Sloop, K.W., Feng, D., Kobilka, T.S. | 3.1 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
2ai0 | K | O | 0 | null | null | null | null | IMMUNE SYSTEM | 07/28/05 | Anti-Cocaine Antibody 7.5.21, Crystal Form III | MUS MUSCULUS | mus musculus | mus musculus | null | Pozharski, E., Hewagama, A., Shanafelt, A., Ringe, D., Petsko, G.A. | 2.2 | X-RAY DIFFRACTION | 0.279 | 0.222 | false | false | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
4imk | B | C | 0 | null | null | null | null | IMMUNE SYSTEM | 01/03/13 | Uncrossed Fab binding to human Angiopoietin 2 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Fenn, S., Schiller, C., Griese, J.J., Hopfner, K.-P., Kettenberger, H. | 2.202 | X-RAY DIFFRACTION | 0.226 | 0.199 | false | true | IGHV1 | IGLV3 | Lambda | null | null | null | null | null |
6bdz | H | L | 0 | A | protein | null | disintegrin and metalloproteinase domain-containing protein10 | MEMBRANE PROTEIN | 10/24/17 | ADAM10 Extracellular Domain Bound by the 11G2 Fab | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Seegar, T.C.M. | 3.1 | X-RAY DIFFRACTION | 0.317 | 0.261 | false | true | IGHV2 | IGKV4 | Kappa | null | null | null | null | null |
4hk3 | J | N | 0 | null | null | null | null | IMMUNE SYSTEM | 10/14/12 | I2 Fab (unbound) from CH65-CH67 Lineage | HOMO SAPIENS | homo sapiens | homo sapiens | null | Schmidt, A.G., Harrison, S.C. | 3.0 | X-RAY DIFFRACTION | 0.290 | 0.221 | false | true | IGHV1 | IGLV3 | Lambda | null | null | null | null | null |
7dc8 | B | A | 0 | C | protein | null | interleukin-6 receptor subunit alpha | IMMUNE SYSTEM | 10/23/20 | Crystal structure of Switch Ab Fab and hIL6R in complex with ATP | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Kadono, S., Fukami, T.A., Kawauchi, H., Torizawa, T., Mimoto, F. | 2.757 | X-RAY DIFFRACTION | 0.278 | 0.207 | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
7rda | H | L | 0 | C | peptide | null | circumsporozoite protein | IMMUNE SYSTEM | 07/09/21 | Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.138 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | plasmodium falciparum | Xu, K., Kwong, P.D. | 1.92 | X-RAY DIFFRACTION | 0.232 | 0.198 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
4f9p | D | d | 0 | B | protein | null | butyrophilin subfamily 3 member a1 | IMMUNE SYSTEM | 05/19/12 | Crystal Structure of the Human BTN3A1 Ectodomain in Complex with the 103.2 Single Chain Antibody | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | Palakodeti, A., Sandstrom, A., Sundaresan, L., Harly, C., Nedellec, S., Olive, D., Scotet, E., Bonneville, M., Adams, E.J. | 3.519 | X-RAY DIFFRACTION | 0.408 | 0.373 | true | true | unknown | unknown | unknown | 0 | -10.673721 | SPR | null | TBD |
3t0v | null | A | 0 | null | null | null | null | DYE-BINDING PROTEIN | 07/20/11 | Unliganded fluorogen activating protein M8VL | HOMO SAPIENS | null | homo sapiens | null | Stanfield, R., Senutovitch, N., Bhattacharyya, S., Rule, G., Wilson, I.A., Armitage, B., Waggoner, A.S., Berget, P. | 1.451 | X-RAY DIFFRACTION | 0.208 | 0.179 | false | true | null | IGLV1 | Lambda | null | null | null | null | null |
7wec | I | K | 0 | C | protein | null | spike glycoprotein | IMMUNE SYSTEM/VIRAL PROTEIN | 12/23/21 | SARS-CoV-2 Omicron variant spike protein with three XGv347 Fabs binding to three closed state RBDs | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Wang, X., Wang, L. | 3.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7omn | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 05/24/21 | Anti-EphA1 JD1-1 VH domain | HOMO SAPIENS | homo sapiens | null | null | Ereno Orbea, J., Nilvebrant, J., Sidhu, S., Julien, J.P. | 1.7 | X-RAY DIFFRACTION | 0.222 | 0.203 | false | true | IGHV3 | null | null | null | null | null | null | null |
3duu | B | A | 0 | B | carbohydrate | KDO | 3-DEOXY-D-MANNO-OCT-2-ULOSONIC ACID | IMMUNE SYSTEM | 07/17/08 | Crystal structure of SAG506-01, orthorhombic, twinned, crystal 2 | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Brooks, C.L., Blackler, R.J., Gerstenbruch, S., Kosma, P., Muller-Loennies, S., Brade, H., Evans, S.V. | 1.95 | X-RAY DIFFRACTION | 0.217 | 0.194 | false | true | IGHV7 | IGKV8 | Kappa | null | null | null | null | null |
4j8r | B | A | 0 | I | peptide | null | major prion protein | IMMUNE SYSTEM | 02/14/13 | Structure of an octapeptide repeat of the prion protein bound to the POM2 Fab antibody fragment | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | mus musculus | Swayampakula, M., Baral, P.K., Kav, N.N.V., Aguzzi, A., James, M.N.G. | 2.303 | X-RAY DIFFRACTION | 0.257 | 0.247 | false | false | IGHV1 | IGKV6 | Kappa | 0 | -10.503274 | Unknown | null | TBD |
6mto | H | L | 0 | T | protein | null | vrc42 epitope t117-f scaffold | IMMUNE SYSTEM | 10/21/18 | Crystal structure of VRC42.01 Fab in complex with T117-F MPER scaffold | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Kwon, Y.D., Druz, A., Law, W.H., Peng, D., Zhang, B., Doria-Rose, N.A., Kwong, P.D. | 2.634 | X-RAY DIFFRACTION | 0.269 | 0.221 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5ojm | M | null | 0 | C | protein | null | human gabaa receptor chimera beta3-alpha5,gamma-aminobutyric acid receptor subunit beta-3,gamma-aminobutyric acid receptor subunit alpha-5 | MEMBRANE PROTEIN | 07/21/17 | Structure of a chimaeric beta3-alpha5 GABAA receptor in complex with nanobody Nb25 | SYNTHETIC CONSTRUCT; HOMO SAPIENS; LAMA GLAMA | lama glama | null | synthetic construct, homo sapiens | Miller, P.S., Scott, S., Masiulis, S., De Colibus, L., Pardon, E., Steyaert, J., Aricescu, A.R. | 3.3 | X-RAY DIFFRACTION | 0.250 | 0.234 | false | true | IGHV1 | null | null | null | null | null | null | null |
6vsr | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 02/11/20 | Crystal structure of macaque anti-HIV-1 antibody RM20F | MACACA MULATTA | macaca mulatta | macaca mulatta | null | Oyen, D., Yuan, M., Wilson, I.A. | 2.176 | X-RAY DIFFRACTION | 0.241 | 0.197 | false | true | IGHV3 | IGKV6 | Kappa | null | null | null | null | null |
4n1c | null | B | 0 | C | protein | null | lysozyme c | Immune system/Hydrolase | 10/03/13 | Structural evidence for antigen receptor evolution | HOMO SAPIENS; GALLUS GALLUS | null | homo sapiens | gallus gallus | Langley, D.B., Rouet, R., Roome, B., Stock, D., Christ, D. | 1.7 | X-RAY DIFFRACTION | 0.233 | 0.197 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
4ydv | H | L | 0 | P | peptide | null | hiv gp41 peptide gp41(596-606) | IMMUNE SYSTEM | 02/23/15 | STRUCTURE OF THE ANTIBODY 7B2 THAT CAPTURES HIV-1 VIRIONS | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Nicely, N.I., Pemble IV, C.W. | 2.7 | X-RAY DIFFRACTION | 0.223 | 0.189 | false | true | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
5vta | I | G | 0 | B | protein | null | dipeptidyl peptidase 4 | HYDROLASE | 05/16/17 | Co-Crystal Structure of DPPIV with a Chemibody Inhibitor | RATTUS NORVEGICUS; MUS MUSCULUS | mus musculus | mus musculus | rattus norvegicus | Wang, Z., Johnstone, S., Cheng, A. | 2.8 | X-RAY DIFFRACTION | 0.300 | 0.250 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
7lja | G | F | 0 | B | protein | null | isoform 2 of potassium channel subfamily k member 4 | METAL TRANSPORT/Immune System | 01/28/21 | Human TRAAK K+ channel FHEIG mutant A198E in a Tl+ bound conductive conformation | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Rietmeijer, R.A., Brohawn, S.G. | 2.77 | X-RAY DIFFRACTION | 0.243 | 0.201 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
1ynk | H | L | 0 | H | Hapten | SC5 | 2-[((R)-{[4-(AMINOMETHYL)PHENYL]AMINO}{[(1R)-1-PHENYLETHYL]AMINO}METHYL)AMINO]ETHANE-1,1-DIOL | IMMUNE SYSTEM | 01/24/05 | Identification of Key residues of the NC6.8 Fab antibody fragment binding to synthetic sweeteners: Crystal structure of NC6.8 co-crystalized with high potency sweetener compound SC45647 | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Gokulan, K., Khare, S., Ronning, D.R., Linthicum, S.D., Sacchettini, J.C., Rupp, B. | 2.1 | X-RAY DIFFRACTION | 0.277 | 0.213 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
3x3f | H | L | 0 | A | protein | null | tumor necrosis factor receptor superfamily member 10b | APOPTOSIS/IMMUNE SYSTEM | 01/20/15 | TRAIL-R2 Extracellular Region Complexed to a Fab fragment from Human Agonist Antibody KMTR2 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Tamada, T. | 2.1 | X-RAY DIFFRACTION | 0.224 | 0.186 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
4w2o | A | null | 0 | B | protein | null | nucleoprotein | IMMUNE SYSTEM | 08/17/17 | Anti-Marburgvirus Nucleoprotein Single Domain Antibody B Complexed with Nucleoprotein C-terminal domain | LAMA GLAMA; LAKE VICTORIA MARBURGVIRUS (STRAIN MUSOKE-80) | lama glama | null | lake victoria marburgvirus (strain musoke-80) | Taylor, A.B., Garza, J.A. | 3.2 | X-RAY DIFFRACTION | 0.285 | 0.227 | false | true | IGHV1 | null | null | null | null | null | null | null |
5zia | G | L | 0 | R | peptide | null | phosphorylated tau peptide | IMMUNE SYSTEM | 03/14/18 | Crystal structure of human anti-tau antibody CBTAU-24.1 in complex with its phosphorylated tau peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Zhang, H., Wilson, I.A. | 2.603 | X-RAY DIFFRACTION | 0.249 | 0.200 | false | true | IGHV1 | IGKV4 | Kappa | 0 | -8.898799 | Unknown | null | TBD |
6cuf | h | l | 0 | c | protein | null | unknown | VIRAL PROTEIN | 03/26/18 | Cryo-EM structure at 4.2 A resolution of vaccine-elicited antibody vFP1.01 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122 | MUS MUSCULUS; HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | mus musculus | mus musculus | human immunodeficiency virus 1 | Acharya, P., Carragher, B., Potter, C.S., Kwong, P.D. | 4.2 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7p02 | H | h | 0 | A | B | G | protein | protein | protein | NA | NA | NA | guanine nucleotide-binding protein g(i) subunit alpha-1,guanine nucleotide-binding protein g(s) subunit alpha isoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | guanine nucleotide-binding protein g(i)/g(s)/g(o) subunitgamma-2 | MEMBRANE PROTEIN | 06/29/21 | Human Neurokinin 1 receptor (NK1R) substance P Gs complex | MUS MUSCULUS; HOMO SAPIENS | mus musculus | null | homo sapiens | homo sapiens | homo sapiens | Thom, C., Ehrenmann, J., Vacca, S., Waltenspuhl, Y., Schoppe, J., Medalia, O., Pluckthun, A. | 2.87 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
6xcn | H | L | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 06/08/20 | Structure of the SARS-CoV-2 spike glycoprotein in complex with the C105 neutralizing antibody Fab fragment (state 2) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Barnes, C.O., Bjorkman, P.J. | 3.66 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
6bi2 | I | M | 0 | null | null | null | null | IMMUNE SYSTEM | 10/31/17 | Trastuzumab Fab D185A (Light Chain) Mutant Biotin Conjugation. | HOMO SAPIENS | homo sapiens | homo sapiens | null | DiDonato, M., Spraggon, G. | 1.801 | X-RAY DIFFRACTION | 0.202 | 0.166 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7bel | C | D | 0 | X | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 12/23/20 | Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in a ternary complex with COVOX-88 and COVOX-45 Fabs | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Zhao, Y., Ren, J., Stuart, D. | 2.53 | X-RAY DIFFRACTION | 0.286 | 0.249 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5i16 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 02/05/16 | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV1-69/IGKV3-11 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Teplyakov, A., Obmolova, G., Malia, T., Luo, J., Gilliland, G. | 1.9 | X-RAY DIFFRACTION | 0.222 | 0.192 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6x08 | K | null | 0 | B | protein | null | nucleoporin nup85 | STRUCTURAL PROTEIN | 05/15/20 | Nup85-Seh1 from S. cerevisiae bound by VHH-SAN2 | SACCHAROMYCES CEREVISIAE (STRAIN ATCC 204508 / S288C); VICUGNA PACOS | vicugna pacos | null | saccharomyces cerevisiae (strain atcc 204508 /s288c) | Nordeen, S.A., Schwartz, T.U. | 4.19 | X-RAY DIFFRACTION | 0.347 | 0.311 | false | true | IGHV1 | null | null | null | null | null | null | null |
5vxr | H | L | 0 | P | peptide | null | virus envelope protein 2 | IMMUNE SYSTEM | 05/24/17 | The antigen-binding fragment of MAb24 in complex with a peptide from Hepatitis C Virus E2 epitope I (412-423) | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | hepatitis c virus | Hardy, J.M., Gu, J., Boo, I., Drummer, H.E., Coulibaly, F.J. | 1.4 | X-RAY DIFFRACTION | 0.190 | 0.171 | false | false | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
7my3 | E | null | 0 | A | protein | null | spike glycoprotein | IMMUNE SYSTEM/VIRAL PROTEIN | 05/20/21 | CryoEM structure of neutralizing nanobody Nb12 in complex with SARS-CoV2 spike | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; MUS MUSCULUS | mus musculus | null | severe acute respiratory syndrome coronavirus2 | Xu, K., Kwong, P.D. | 2.9 | ELECTRON MICROSCOPY | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
6okm | H | L | 0 | R | protein | null | tumor necrosis factor receptor superfamily member 4 | IMMUNE SYSTEM | 04/14/19 | Human OX40R (TNFRSF4) bound to Fab 3C8 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Boenig, G., Ultsch, M.H., Harris, S.F. | 2.1 | X-RAY DIFFRACTION | 0.238 | 0.211 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
2r56 | I | M | 0 | B | protein | null | beta-lactoglobulin | IMMUNE SYSTEM | 09/03/07 | Crystal Structure of a Recombinant IgE Fab Fragment in Complex with Bovine Beta-Lactoglobulin Allergen | BOS TAURUS; HOMO SAPIENS | homo sapiens | homo sapiens | bos taurus | Niemi, M., Kallio, J.M., Hakulinen, N., Rouvinen, J. | 2.8 | X-RAY DIFFRACTION | 0.291 | 0.246 | false | false | IGHV3 | IGKV1 | Kappa | 0 | -12.12 | SPR | null | 17997967 |
7bej | H | L | 0 | E | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 12/23/20 | Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-158 Fab (crystal form 1) | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Zhao, Y., Ren, J., Stuart, D. | 2.42 | X-RAY DIFFRACTION | 0.231 | 0.190 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5x2o | J | K | 0 | C | D | protein | protein | NA | NA | taste receptor, type 1, member 2a | taste receptor, type 1, member 3 | SIGNALING PROTEIN/IMMUNE SYSTEM | 02/02/17 | Crystal structure of the medaka fish taste receptor T1r2a-T1r3 ligand binding domains in complex with L-arginine | ORYZIAS LATIPES; MUS MUSCULUS | mus musculus | mus musculus | oryzias latipes | oryzias latipes | Nuemket, N., Yasui, N., Atsumi, N., Yamashita, A. | 2.6 | X-RAY DIFFRACTION | 0.272 | 0.185 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
3j42 | K | L | 0 | F | protein | null | prm | VIRUS/IMMUNE SYSTEM | 06/13/13 | Obstruction of Dengue Virus Maturation by Fab Fragments of the 2H2 Antibody | MUS MUSCULUS; DENGUE VIRUS 2 | mus musculus | mus musculus | dengue virus 2 | Wang, Z., Pennington, J.G., Jiang, W., Rossmann, M.G. | 21 | ELECTRON MICROSCOPY | null | null | false | true | IGHV5 | IGKV6 | Kappa | null | null | null | null | null |
7l2e | H | L | 0 | A | protein | null | spike glycoprotein | Viral Protein/IMMUNE SYSTEM | 12/16/20 | Cryo-EM structure of NTD-directed neutralizing antibody 4-18 in complex with prefusion SARS-CoV-2 spike glycoprotein | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Cerutti, G., Shapiro, L. | 2.97 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
1g6v | K | null | 0 | A | protein | null | carbonic anhydrase | LYASE/IMMUNE SYSTEM | 11/08/00 | Complex of the camelid heavy-chain antibody fragment CAB-CA05 with bovine carbonic anhydrase | CAMELUS DROMEDARIUS; BOS TAURUS | camelus dromedarius | null | bos taurus | Desmyter, A., Decanniere, K., Muyldermans, S., Wyns, L. | 3.5 | X-RAY DIFFRACTION | 0.276 | 0.210 | false | true | IGHV1 | null | null | 0 | -9.74 | SPR | null | 11342547 |
6z7w | D | C | 0 | K | L | peptide | peptide | NA | NA | insulin | insulin | HORMONE | 06/02/20 | Human insulin in complex with the analytical antibody HUI-018 Fab | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | homo sapiens | Johansson, E. | 2.42 | X-RAY DIFFRACTION | 0.275 | 0.209 | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
4llu | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 07/09/13 | Structure of Pertuzumab Fab with light chain Clambda at 2.16A | HOMO SAPIENS | homo sapiens | homo sapiens | null | Pustilnik, A., Lewis, S.M., Wu, X., Sereno, A., Huang, F., Guntas, G., Leaver-Fay, A., Smith, E.M., Ho, C., Hansen-Estruch, C., Chamberlain, A.K., Truhlar, S.M., Kuhlman, B., Demarest, S.J., Atwell, S. | 2.16 | X-RAY DIFFRACTION | 0.273 | 0.222 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7s0x | C | D | 0 | F | protein | null | circumsporozoite protein | IMMUNE SYSTEM | 08/31/21 | Fab352 in complex with the C-terminal alphaTSR domain of P. falciparum | HOMO SAPIENS; PLASMODIUM FALCIPARUM (ISOLATE 3D7) | homo sapiens | homo sapiens | plasmodium falciparum (isolate 3d7) | Pholcharee, T., Oyen, D., Wilson, I.A. | 2.8 | X-RAY DIFFRACTION | 0.276 | 0.225 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
5gs3 | H | h | 0 | null | null | null | null | IMMUNE SYSTEM | 08/13/16 | Crystal structure of diabody | HOMO SAPIENS | homo sapiens | null | null | Kim, J.H., Song, D.H., Youn, S.J., Kim, J.W., Cho, G., Lee, H., Lee, J.O. | 1.698 | X-RAY DIFFRACTION | 0.211 | 0.192 | true | true | unknown | unknown | unknown | null | null | null | null | null |
6cde | H | L | 0 | D | protein | null | glycoprotein 41 | VIRAL PROTEIN | 02/08/18 | Cryo-EM structure at 3.8 A resolution of vaccine-elicited antibody vFP20.01 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122 | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Xu, K., Liu, K., Carragher, B., Potter, C.S., Kwong, P.D. | 3.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6l8t | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 11/07/19 | Crystal structure of the Fab fragment of a humanized HBV therapeutic antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | He, M.Z., Gu, Y., Li, S.W. | 1.766 | X-RAY DIFFRACTION | 0.192 | 0.165 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6nb6 | I | M | 0 | B | protein | null | spike glycoprotein | VIRUS | 12/06/18 | SARS-CoV complex with human neutralizing S230 antibody Fab fragment (state 1) | SARS CORONAVIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | sars coronavirus | Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 4.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
7dcx | B | G | 0 | D | protein | null | sars-cov2 s protein | VIRAL PROTEIN | 10/27/20 | S-3C1-F3a structure, two RBDs are up and one RBD is down, each RBD binds with a 3C1 fab. | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; MUS MUSCULUS | mus musculus | mus musculus | severe acute respiratory syndrome coronavirus2 | Cong, Y., Liu, C.X. | 5.9 | ELECTRON MICROSCOPY | null | null | false | false | IGHV3 | IGKV6 | Kappa | null | null | null | null | null |
1g9e | A | null | 15 | null | null | null | null | IMMUNE SYSTEM | 11/23/00 | SOLUTION STRUCTURE AND RELAXATION MEASUREMENTS OF AN ANTIGEN-FREE HEAVY CHAIN VARIABLE DOMAIN (VHH) FROM LLAMA | LAMA GLAMA | lama glama | null | null | Renisio, J.-G., Perez, J., Czisch, M., Guenneugues, M., Bornet, O., Frenken, L., Cambillau, C., Darbon, H. | NOT | SOLUTION NMR | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
2qhr | H | L | 0 | P | peptide | null | envelope glycoprotein peptide | Immune system/viral protein | 07/02/07 | Crystal structure of the 13F6-1-2 Fab fragment bound to its Ebola virus glycoprotein peptide epitope. | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Lee, J.E., Kuehne, A., Abelson, D.M., Fusco, M.L., Hart, M.K., Saphire, E.O. | 2.0 | X-RAY DIFFRACTION | 0.245 | 0.203 | false | false | IGHV5 | IGLV3 | Lambda | 0 | -10.07 | SPR | 25 | 18005986 |
7zfe | J | K | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN | 04/01/22 | SARS-CoV-2 Omicron RBD in complex with Omi-32 Fab and nanobody C1 | LAMA GLAMA; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Huo, J., Ren, J., Stuart, D.I. | 3.25 | X-RAY DIFFRACTION | 0.293 | 0.237 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
5dup | H | L | 0 | A | protein | null | hemagglutinin | IMMUNE SYSTEM | 09/20/15 | Influenza A virus H5 hemagglutinin globular head in complex with antibody AVFluIgG03 | HOMO SAPIENS; INFLUENZA A VIRUS (A/ANHUI/1/2005(H5N1)) | homo sapiens | homo sapiens | influenza a virus (a/anhui/1/2005(h5n1)) | Zuo, T., Sun, J., Wang, G., Zhou, P., Wang, X., Zhang, L. | 3.052 | X-RAY DIFFRACTION | 0.257 | 0.199 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
5fhc | A | B | 0 | J | protein | null | envelope glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 12/21/15 | Crystal Structure of Protective Human Antibodies 100 and 114 in Complex with Ebola Virus Fusion Glycoprotein (GP) | HOMO SAPIENS; ZAIRE EBOLAVIRUS; ZAIRE EBOLAVIRUS (STRAIN MAYINGA-76) | homo sapiens | homo sapiens | zaire ebolavirus (strain mayinga-76) | Gilman, M.S.A., McLellan, J.S. | 6.704 | X-RAY DIFFRACTION | 0.343 | 0.260 | false | true | IGHV4 | IGLV3 | Lambda | null | null | null | null | null |
7orb | H | L | 0 | R | protein | null | spike protein s1 | VIRAL PROTEIN | 06/04/21 | Crystal structure of the L452R mutant receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-75 and COVOX-253 Fabs | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Ren, J., Stuart, D.I. | 2.5 | X-RAY DIFFRACTION | 0.251 | 0.213 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5tlj | F | E | 0 | null | null | null | null | IMMUNE SYSTEM | 10/11/16 | COMPLEX BETWEEN HUMAN CD27 AND FAB FRAGMENTS OF ANTIBODIES M2177 AND M2191 | HOMO SAPIENS; MUS MUSCULUS, HOMO SAPIENS | mus musculus, homo sapiens | mus musculus, homo sapiens | null | Teplyakov, A., Obmolova, G., Malia, T., Gilliland, G.L. | 3.5 | X-RAY DIFFRACTION | 0.356 | 0.283 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7jkm | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 07/28/20 | REGN1 Human Fab in complex with anti-Kappa VHH domain | HOMO SAPIENS; LAMA GLAMA | homo sapiens | homo sapiens | null | Dennis, T.N., de la Cruz, M., Williams, J.C. | 1.78 | X-RAY DIFFRACTION | 0.210 | 0.182 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4hkb | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 10/15/12 | CH67 Fab (unbound) from the CH65-67 Lineage | HOMO SAPIENS | homo sapiens | homo sapiens | null | Schmidt, A.G., Harrison, S.C. | 3.6 | X-RAY DIFFRACTION | 0.306 | 0.258 | false | true | IGHV1 | IGLV3 | Lambda | null | null | null | null | null |
4hc1 | M | N | 0 | B | protein | null | mucosal addressin cell adhesion molecule 1 | IMMUNE SYSTEM | 09/28/12 | Crystal structure of a loop deleted mutant of human MAdCAM-1 D1D2 complexed with Fab 10G3 | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Springer, T., Yu, Y., Zhu, J. | 2.871 | X-RAY DIFFRACTION | 0.253 | 0.200 | false | true | IGHV3 | IGKV14 | Kappa | null | null | null | null | null |
4qex | I | M | 0 | B | protein | null | erythrocyte-binding antigen-175 | IMMUNE SYSTEM | 05/19/14 | Crystal structure of PfEBA-175 RII in complex with a Fab fragment from inhibitory antibody R217 | PLASMODIUM FALCIPARUM; MUS MUSCULUS | mus musculus | mus musculus | plasmodium falciparum | Chen, E., Paing, M.M., Salinas, N., Sim, B.K., Tolia, N.H. | 4.5 | X-RAY DIFFRACTION | 0.285 | 0.232 | false | false | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5dsc | E | F | 0 | M | peptide | null | peptide | IMMUNE SYSTEM | 09/17/15 | Context-independent anti-hypusine antibody FabHpu24.B in complex with hypusine | ORYCTOLAGUS CUNICULUS; SYNTHETIC CONSTRUCT | oryctolagus cuniculus | oryctolagus cuniculus | synthetic construct | Zhai, Q., Carter, P.J. | 2.4 | X-RAY DIFFRACTION | 0.248 | 0.207 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5nqw | C | null | 0 | B | protein | null | immunoglobulin heavy constant epsilon | IMMUNE SYSTEM | 04/21/17 | IgE-Fc in complex with single domain antibody 026 | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Laursen, N.S., Jabs, F., Spillner, E., Andersen, G.R. | 3.4 | X-RAY DIFFRACTION | 0.241 | 0.212 | false | true | IGHV3 | null | null | 0 | -12.078842 | SPR | null | TBD |
3mlt | H | L | 0 | P | peptide | null | hiv-1 gp120 third variable region (v3) crown | IMMUNE SYSTEM | 04/18/10 | Crystal structure of anti-HIV-1 V3 Fab 2557 in complex with a UG1033 V3 peptide | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Kong, X.-P. | 2.49 | X-RAY DIFFRACTION | 0.280 | 0.202 | false | false | IGHV5 | IGLV3 | Lambda | null | null | null | null | null |
6osy | H | L | 0 | A | protein | null | bg505 gp41 | IMMUNE SYSTEM | 05/02/19 | Cryo-EM structure of vaccine-elicited antibody 0PV-a.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Gorman, J., Kwong, P.D. | 4.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
2fb4 | H | L | 0 | null | null | null | null | IMMUNOGLOBULIN | 04/18/89 | DIR PRIMAERSTRUKTUR DES KRISTALLISIERBAREN MONOKLONALEN IMMUNOGLOBULINS IGG1 KOL. II. AMINOSAEURESEQUENZ DER L-KETTE, LAMBDA-TYP, SUBGRUPPE I (GERMAN) | HOMO SAPIENS | homo sapiens | homo sapiens | null | Marquart, M., Huber, R. | 1.9 | X-RAY DIFFRACTION | unknown | 0.189 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
7lq7 | H | L | 0 | A | protein | null | spike protein s1 | IMMUNE SYSTEM | 02/13/21 | Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CV503 and COVA1-16 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Yuan, M., Zhu, X., Wilson, I.A. | 3.4 | X-RAY DIFFRACTION | 0.233 | 0.197 | false | true | IGHV1 | IGLV2 | Lambda | null | null | null | null | null |
6k4z | A | a | 0 | a | Hapten | NPA | 2-(4-HYDROXY-3-NITROPHENYL)ACETIC ACID | IMMUNE SYSTEM | 05/27/19 | Single-chain Fv antibody of C6 COMPLEXED WITH 2-(4-HYDROXY-3-NITROPHENYL)ACETIC ACID | MUS MUSCULUS | mus musculus | null | null | Nishiguchi, A., Numoto, N., Ito, N., Azuma, T., Oda, M. | 1.65 | X-RAY DIFFRACTION | 0.196 | 0.167 | true | true | unknown | unknown | unknown | null | null | null | null | null |
7qbf | B | null | 0 | A | protein | null | transcobalamin-2 | TRANSPORT PROTEIN | 11/19/21 | TC:CD320 in complex with nanobody TC-Nb34 | HOMO SAPIENS; VICUGNA PACOS | vicugna pacos | null | homo sapiens | Bloch, J.S., Locher, K.P. | 1.85 | X-RAY DIFFRACTION | 0.205 | 0.174 | false | true | IGHV1 | null | null | null | null | null | null | null |
5mi0 | B | C | 0 | A | protein | null | reticulocyte binding-like protein 5,reticulocyte bindingprotein 5 | IMMUNE SYSTEM | 11/27/16 | A thermally stabilised version of Plasmodium falciparum RH5 | PLASMODIUM FALCIPARUM; MUS MUSCULUS | mus musculus | mus musculus | plasmodium falciparum | Campeotto, I., Goldenzweig, A., Davey, J., Barfod, L., Marshall, J.M., Silk, S.E., Wright, K.E., Draper, S.J., Higgins, M.K., Fleishman, S.J. | 2.35 | X-RAY DIFFRACTION | 0.222 | 0.176 | false | true | IGHV5 | IGKV3 | Kappa | 0 | -8.713722 | SPR | null | TBD |
4ma1 | B | C | 0 | null | null | null | null | IMMUNE SYSTEM | 08/15/13 | Unliganded 3 crystal structure of S25-26 Fab | MUS MUSCULUS | mus musculus | mus musculus | null | Haji-Ghassemi, O., Evans, S.V. | 2.32 | X-RAY DIFFRACTION | 0.260 | 0.229 | false | false | IGHV2 | IGKV1 | Kappa | null | null | null | null | null |
5jor | D | A | 0 | null | null | null | null | IMMUNE SYSTEM | 05/02/16 | Crystal structure of unbound anti-glycan antibody Fab14.22 at 2.2 A | MUS MUSCULUS | mus musculus | mus musculus | null | Sarkar, A., Irimia, A., Teyton, L., Wilson, I.A. | 2.206 | X-RAY DIFFRACTION | 0.237 | 0.205 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6nip | H | L | 0 | Z | protein | null | envelope protein e | VIRAL PROTEIN/IMMUNE SYSTEM | 12/31/18 | Crystal structure of a human anti-ZIKV-DENV neutralizing antibody MZ1 in complex with ZIKV E glycoprotein | HOMO SAPIENS; ZIKA VIRUS (ISOLATE ZIKV/HUMAN/FRENCH POLYNESIA/10087PF/2013) | homo sapiens | homo sapiens | zika virus (isolate zikv/human/frenchpolynesia/10087pf/2013) | Sankhala, R.S., Dussupt, V., Donofrio, G., Choe, M., Modjarrad, K., Michael, N.L., Krebs, S.J., Joyce, M.G. | 4.16 | X-RAY DIFFRACTION | 0.237 | 0.188 | false | true | IGHV4 | IGLV1 | Lambda | null | null | null | null | null |
7r63 | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 06/22/21 | Nb82, a nanobody against voltage gated sodium channels Nav1.4 and Nav1.5 | LAMA GLAMA | lama glama | null | null | Srinivasan, L., Gabelli, S.B. | 2.0 | X-RAY DIFFRACTION | 0.244 | 0.184 | false | true | IGHV1 | null | null | null | null | null | null | null |
3ulu | D | C | 0 | A | protein | null | toll-like receptor 3 | IMMUNE SYSTEM | 11/11/11 | Structure of quaternary complex of human TLR3ecd with three Fabs (Form1) | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Luo, J., Gilliland, G.L., Obmolova, O., Malia, T., Teplyakov, A. | 3.52 | X-RAY DIFFRACTION | 0.309 | 0.268 | false | true | IGHV6 | IGLV3 | Lambda | null | null | null | null | null |
3j8v | F | J | 0 | D | protein | null | l1 | VIRUS/IMMUNE SYSTEM | 11/19/14 | Cryo-EM reconstruction of quasi-HPV16 complex with H16.14J Fab | HUMAN PAPILLOMAVIRUS TYPE 16; MUS MUSCULUS | mus musculus | mus musculus | human papillomavirus type 16 | Guan, J., Hafenstein, S. | 13.9 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV13 | Kappa | null | null | null | null | null |
6w51 | O | P | 0 | D | F | protein | peptide | NA | NA | mhc class i antigen | cellular tumor antigen p53 peptide | IMMUNE SYSTEM | 03/12/20 | Structure of the antibody fragment H2 in complex with HLA-A*02:01/p53R175H | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | homo sapiens | Wright, K.M., Gabelli, S.B. | 3.53 | X-RAY DIFFRACTION | 0.283 | 0.200 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7tm0 | E | D | 0 | C | protein | null | spike glycoprotein | VIRUS | 01/19/22 | SARS-CoV-2 S B.1.1.529 Omicron variant + S309 + S2L20 Global Refinement | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | McCallum, M., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 3.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
1vfb | B | A | 0 | C | protein | null | hen egg white lysozyme | IMMUNOGLOBULIN/HYDROLASE(O-GLYCOSYL) | 12/03/93 | BOUND WATER MOLECULES AND CONFORMATIONAL STABILIZATION HELP MEDIATE AN ANTIGEN-ANTIBODY ASSOCIATION | MUS MUSCULUS; GALLUS GALLUS | mus musculus | mus musculus | gallus gallus | Bhat, T.N., Poljak, R.J. | 1.8 | X-RAY DIFFRACTION | unknown | 0.185 | false | true | IGHV2 | IGKV12 | Kappa | 0 | -11.47 | ITC | 24 | 8302837 |
2p42 | D | null | 0 | C | protein | null | ribonuclease pancreatic | HYDROLASE/IMMUNE SYSTEM | 03/11/07 | Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.8A resolution: SE3-mono-2 crystal form with three se-met sites (M34, M51, M83) in vhh scaffold | CAMELUS DROMEDARIUS; BOS TAURUS | camelus dromedarius | null | bos taurus | Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A. | 1.8 | X-RAY DIFFRACTION | 0.215 | 0.171 | false | true | IGHV1 | null | null | 0 | -10.59 | Other | 30 | 18445622 |
3kj6 | H | L | 0 | A | protein | null | beta-2 adrenergic receptor | SIGNALING PROTEIN | 11/02/09 | Crystal structure of a Methylated beta2 Adrenergic Receptor-Fab complex | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Bokoch, M.P., Zou, Y., Rasmussen, S.G.F., Liu, C.W., Nygaard, R., Rosenbaum, D.M., Fung, J.J., Choi, H.-J., Thian, F.S., Kobilka, T.S., Puglisi, J.D., Weis, W.I., Pardo, L., Prosser, S., Mueller, L., Kobilka, B.K. | 3.4 | X-RAY DIFFRACTION | 0.280 | 0.238 | false | true | IGHV1 | IGKV14 | Kappa | null | null | null | null | null |
6cde | M | N | 0 | C | protein | null | glycoprotein 120 | VIRAL PROTEIN | 02/08/18 | Cryo-EM structure at 3.8 A resolution of vaccine-elicited antibody vFP20.01 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122 | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Xu, K., Liu, K., Carragher, B., Potter, C.S., Kwong, P.D. | 3.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | unknown | unknown | null | null | null | null | null |
4gw4 | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 08/31/12 | Crystal structure of 3BNC60 Fab with P61A mutation | HOMO SAPIENS | homo sapiens | homo sapiens | null | Diskin, R., Fu, B.Z., Bjorkman, P.J. | 2.65 | X-RAY DIFFRACTION | 0.256 | 0.213 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7ra8 | C | D | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 06/30/21 | SARS-CoV-2 S glycoprotein in complex with S2X259 Fab | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Veesler, D., Tortorici, M.A., Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 3.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
6xsk | I | K | 0 | B | A | protein | protein | NA | NA | hemagglutinin ha2 chain | hemagglutinin ha1 chain | IMMUNE SYSTEM/Viral Protein | 07/15/20 | Cryo-EM structure of vaccine-elicited Rhesus VH6-1 antibody 789-203-3C12 in complex with stabilized SI06 (A/Solomon Islands/3/06) Influenza Hemagglutinin Trimer | MACACA MULATTA; INFLUENZA A VIRUS (A/SOLOMON ISLANDS/3/2006(H1N1)) | macaca mulatta | macaca mulatta | influenza a virus (a/solomonislands/3/2006(h1n1)) | influenza a virus (a/solomonislands/3/2006(h1n1)) | Cerutti, G., Gorman, J., Kwong, P.D., Shapiro, L. | 3.85 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
6rp8 | h | l | 0 | c | protein | null | unknown | IMMUNE SYSTEM | 05/14/19 | Crystal Structure of Ipilimumab Fab complexed with CTLA-4 at 2.6A resolution | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Zhang, F., Zhou, A. | 2.6 | X-RAY DIFFRACTION | 0.267 | 0.211 | false | false | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
7jkb | B | null | 0 | null | null | null | null | IMMUNE SYSTEM | 07/28/20 | 2xVH Fab | HOMO SAPIENS | homo sapiens | null | null | Lord, D.M., Zhou, Y.F. | 2.55 | X-RAY DIFFRACTION | 0.292 | 0.254 | false | true | IGHV3 | null | null | null | null | null | null | null |
3hi6 | H | L | 0 | A | protein | null | integrin alpha-l | cell adhesion/immune system | 05/19/09 | Crystal structure of intermediate affinity I domain of integrin LFA-1 with the Fab fragment of its antibody AL-57 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Zhang, H., Wang, J. | 2.3 | X-RAY DIFFRACTION | 0.226 | 0.170 | false | true | IGHV3 | IGKV1 | Kappa | 0.000005 | -7.26 | SPR | null | 19805116 |
2kqm | null | A | 4 | null | null | null | null | IMMUNE SYSTEM | 11/11/09 | Solution structure of the KI O18/O8 Y87H immunoglobulin light chain variable domain | HOMO SAPIENS | null | homo sapiens | null | Volkman, B.F., Peterson, F.C., Ramirez-Alvarado, M., Baden, E.M. | NOT | SOLUTION NMR | null | null | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
6awo | B | C | 0 | A | protein | null | sodium-dependent serotonin transporter | TRANSPORT PROTEIN | 09/06/17 | X-ray structure of the ts3 human serotonin transporter complexed with sertraline at the central site | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Coleman, J.A., Gouaux, E. | 3.534 | X-RAY DIFFRACTION | 0.283 | 0.262 | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
3upc | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 11/17/11 | A general strategy for the generation of human antibody variable domains with increased aggregation resistance | HOMO SAPIENS | homo sapiens | null | null | Dudgeon, K., Rouet, R., Kokmeijer, I., Langley, D.B., Christ, D. | 2.8 | X-RAY DIFFRACTION | 0.247 | 0.209 | false | true | IGHV3 | null | null | null | null | null | null | null |
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