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NCT02620579 | 1:17:chronic_disease | major depression | 2 | [
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NCT01903330 | 86:112:cancer,114:137:cancer,142:153:cancer | Patients must have histologically confirmed diagnosis of a recurrent/progressive WHO grade IV malignant gliomas (glioblastoma multiforme and gliosarcoma) | 2 | [
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NCT02497300 | 1:21:chronic_disease | cognitive impairment prohibiting consent | 2 | [
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NCT02256631 | 18:31:chronic_disease | Documentation of HIV infection | 2 | [
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NCT02316574 | 13:33:chronic_disease | Significant cognitive impairment | 2 | [
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NCT02503358 | ,,113:122:treatment,,,203:224:treatment,238:252:treatment | Males of child bearing potential must agree to practice effective barrier contraception during the entire study treatment period and through 6 months) after the last dose of study drug, (includes males surgically sterilized (i.e. status post vasectomy) | 2 | [
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NCT03072238 | 21:35:chronic_disease,37:46:chronic_disease,51:72:chronic_disease | Any other diseases, cardiovascular, pulmonary, or metabolic dysfunction, physical examination finding, or clinical laboratory finding giving reasonable suspicion of a disease or condition that contraindicates the use of an investigational drug or that may affect the interpretation of the results or renders the particip... | 2 | [
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NCT02227199 | 27:42:chronic_disease | patients with evidence of lymphadenopathy in the neck must have a dedicated CT of neck | 2 | [
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NCT02514083 | 32:66:treatment,74:86:treatment,108:117:treatment,153:162:treatment | Subjects who received a strong cytochrome P450 (CYP) 3A inhibitor within 7 days prior to the first dose of ibrutinib or subjects who require continuous treatment with a strong CYP3A inhibitor | 2 | [
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NCT02452203 | 34:54:chronic_disease | Participant meets criteria for a DSM5 Axis-1 disorder | 2 | [
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NCT02236000 | 52:77:chronic_disease | other disease or condition significantly affecting gastrointestinal function | 2 | [
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NCT02570984 | 12:28:chronic_disease | History of hypoxic seizures during a wheezing episode | 2 | [
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NCT02234557 | 1:45:chronic_disease | Comorbid oppositional defiant disorder (ODD) and simple phobias are permitted | 2 | [
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NCT02332291 | 1:7:chronic_disease | stroke | 2 | [
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NCT01953575 | 15:18:chronic_disease,31:40:chronic_disease,,134:151:treatment,,192:221:treatment | Patients with EoE, defined as dysphagia with histologic finding of greater than or equal to 15 eosinophils per high powered field on esophageal biopsy despite at least 6 weeks of twice daily proton pump inhibitor therapy | 2 | [
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NCT02966665 | 13:26:chronic_disease,, | Significant renal disease (Glomerular Filtration Rate < 50 mL/min/1.73m2) | 2 | [
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NCT02530034 | 1:38:cancer | chronic myelomonocytic leukemia (CMML) | 2 | [
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NCT01859819 | 1:26:cancer | B-Lymphoblastic lymphomas | 2 | [
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NCT02114229 | ,,,82:106:chronic_disease | Performance status defined by Karnofsky or Lansky > 30 (except for patients with posterior fossa syndrome) | 2 | [
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NCT02579967 | 19:41:chronic_disease | Infection with an opportunistic organism | 2 | [
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NCT02290951 | 1:37:treatment | Allogeneic stem cell transplantation | 2 | [
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NCT02565966 | ,,13:29:treatment | 3 - 4 weeks prior to surgery | 2 | [
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NCT01758042 | 14:28:treatment | Existence of haploidentical first degree relative who passes standard donor evaluations for bone marrow and kidney donation | 2 | [
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NCT01626079 | ,,,63:76:treatment | New York Heart Association (NYHA) Functional Class II, III or ambulatory IV | 2 | [
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NCT03016871 | 34:44:cancer,,97:115:treatment,119:139:cancer,143:178:cancer,183:201:cancer,206:230:cancer,237:253:treatment | Diagnosed or treated for another malignancy within 3 years of enrollment, with the exception of complete resection of basal cell carcinoma or squamous cell carcinoma of the skin, an in situ malignancy, or low-risk prostate cancer after curative therapy | 2 | [
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NCT02050113 | 10:31:chronic_disease,33:56:chronic_disease,61:82:chronic_disease | Previous myocardial infarction, coronary artery disease, or coronary artery stent | 2 | [
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NCT01947140 | 34:49:treatment | No upper limit for the number of prior therapies | 2 | [
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NCT01925573 | 23:37:treatment,45:53:treatment,57:68:treatment | Patients on full-dose anticoagulants (e.g., warfarin or LMW heparin) | 2 | [
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NCT02452203 | 16:30:chronic_disease,, | Participant is morbidly obese (BMI > 40) | 2 | [
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NCT03116685 | 18:41:chronic_disease,28:41:chronic_disease,69:86:treatment,98:123:chronic_disease,132:147:chronic_disease,157:183:chronic_disease,188:208:chronic_disease | The existence of secondary hyperoxaluria, e.g. hyperoxaluria due to bariatric surgery or chronic gastrointestinal diseases such as cystic fibrosis, chronic inflammatory bowel disease and short-bowel syndrome | 2 | [
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NCT03137771 | ,103:119:treatment | Patients must be registered within 35 days of administration of the last dose of first-line/induction systemic therapy | 2 | [
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NCT02451488 | 1:28:chronic_disease,34:37:chronic_disease,39:50:chronic_disease,54:65:chronic_disease | Active or chronic infection with HIV, hepatitis B or hepatitis C | 2 | [
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NCT02493530 | 81:92:treatment | Patients with these diagnoses may be eligible, provided they are able to obtain ruxolitinib from commercial supply | 2 | [
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NCT00579514 | 70:76:cancer | Patients of Ashkenazi Jewish ancestry with a histologic diagnosis of cancer of any type | 2 | [
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NCT02939183 | 1:19:chronic_disease, | Measurable disease (assessed within 28 days prior to day 1) | 2 | [
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NCT01681264 | 30:37:treatment,39:52:treatment,54:63:treatment,68:88:treatment | Tests positive for non-study opioids, illicit drugs, marijuana, or non-prescribed drugs | 2 | [
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NCT02171429 | 22:31:chronic_disease,42:51:treatment,57:85:treatment,,123:139:treatment, | Any major episode of infection requiring treatment with intravenous (IV) antibiotics within 8 weeks prior to screening or oral antibiotics within 4 weeks prior to screening | 2 | [
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NCT03078192 | 27:30:chronic_disease,32:59:chronic_disease,63:75:chronic_disease,77:114:chronic_disease,118:143:chronic_disease,148:153:chronic_disease | Either has a diagnosis of PAH, isolated left heart disease or lung disease (chronic obstructive pulmonary disease or interstitial lung disease) or CTEPH using established clinical criteria | 2 | [
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NCT02579096 | 70:94:treatment, | Previous history of failure to reach target uric acid levels despite therapy with allopurinol at dose > 300 mg/day | 2 | [
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NCT02464696 | 1:29:chronic_disease | Supraventricular tachycardia | 2 | [
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NCT02232165 | 10:17:chronic_disease,19:28:chronic_disease,30:37:chronic_disease,41:54:chronic_disease | Advanced cardiac, pulmonary, hepatic or liver disease | 2 | [
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NCT02324387 | 15:45:treatment | scheduled for neoadjuvant chemotherapy (NAC) | 2 | [
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NCT03070535 | 17:42:chronic_disease,61:81:treatment,85:92:treatment | Diabetes: Known type 1 or Type 2 diabetes, currently taking diabetic medications or insulin | 2 | [
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NCT01459107 | 1:45:chronic_disease | Type I (insulin-dependent) diabetes mellitus | 2 | [
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NCT02783157 | 1:8:chronic_disease | Hepatic | 2 | [
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NCT01422746 | 4:15:treatment,152:176:treatment,178:188:treatment,190:199:treatment,201:216:treatment,222:235:treatment | No medications known to affect the reproductive system or glucose metabolism can be taken in the 3 months prior to the study. Such medications include oral contraceptive pills, progestins, metformin, glucocorticoids, and psychotropics | 2 | [
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NCT02000115 | 1:20:chronic_disease,,,53:76:chronic_disease,95:103:treatment | Renal insufficiency (creatinine > 3.0 mg/dL) and/or end stage renal disease requiring chronic dialysis | 2 | [
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NCT02467478 | ,34:61:treatment | post-menopausal women who are on hormone replacement therapy | 2 | [
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NCT02064673 | 1:4:cancer,8:10:cancer,14:35:cancer | T3b or T4 or node positive disease | 2 | [
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NCT02056288 | 1:19:chronic_disease | Bleeding diathesis | 2 | [
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NCT02494141 | 59:62:treatment,80:94:chronic_disease,96:104:treatment | Inability to cooperate with/clinical contraindication for MRI including severe claustrophobia, implants, devices, or non-removable body piercings | 2 | [
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NCT02287558 | 1:22:chronic_disease | Peripheral neuropathy, as determined from neurologic consultation | 2 | [
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NCT02451215 | 1:31:cancer | Choroid plexus papilloma (CPP) | 2 | [
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NCT02946658 | 20:43:chronic_disease | Prior Diagnosis of moderate to severe COPD | 2 | [
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NCT01438073 | 4:15:treatment, | no medications known to affect reproductive endocrine function for at least 2 months except for medications used to treat the subject's reproductive condition | 2 | [
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NCT02530463 | 25:34:treatment | Previously treated with HMA agent | 2 | [
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NCT02000115 | 8:30:chronic_disease, | Active bacterial endocarditis within 6 months prior to the index procedure | 2 | [
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NCT03098082 | 1:27:chronic_disease | Stage 3 or 4 renal disease and/or oliguria | 2 | [
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NCT02682407 | 22:26:chronic_disease,28:43:chronic_disease,45:47:chronic_disease,52:69:chronic_disease,80:101:chronic_disease | Have a diagnosis of: IgAN, Lupus Nephritis, MN, or C3 Glomerulopathy including Dense Deposit Disease | 2 | [
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NCT02580981 | 23:29:cancer | Not willing to obtain cancer care at the University of New Mexico | 2 | [
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NCT03153982 | 9:25:chronic_disease,36:55:treatment,59:77:treatment | Current active infection requiring systemic antibiotic or antifungal therapy | 2 | [
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NCT03073343 | 7:20:chronic_disease | Known HIV infection | 2 | [
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NCT03001830 | 25:30:chronic_disease,, | Serological evidence of HIV-1 who have CD4 counts ≤ 200/mm3 | 2 | [
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NCT00584649 | 74:92:treatment, | Any medical condition significantly increasing the risk of extending the ablation procedure or of X ray exposure, including pregnancy | 2 | [
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NCT02286687 | 192:206:chronic_disease,316:322:cancer,326:340:cancer | Patients must have one of the following: somatic mutations or deletions in BRCA1 or BRCA2; genomic alterations in other BRCA pathway genes (subcohorts: a. ATM, b. PALB2, c. other genes, e.g. Fanconi Anemia genes, ARID1A, MER11, RAD50, NBS1, ATR; amplification of EMSY); or germline mutation in BRCA1 or BRCA 2 (not breas... | 2 | [
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NCT02271711 | 1:20:treatment | replacement therapy | 2 | [
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NCT02323880 | 51:60:treatment | Patients must not have received prior exposure to selinexor | 2 | [
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NCT02635360 | 1:19:cancer | Distant metastases | 2 | [
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NCT02354703 | 40:53:chronic_disease,55:71:chronic_disease,82:100:chronic_disease,139:164:chronic_disease,166:196:chronic_disease,198:212:chronic_disease,214:229:chronic_disease | The subject has a current diagnosis of schizophrenia, bipolar disorder, or other psychotic disorder, or a non-psychotic diagnosis such as major depressive disorder, post-traumatic stress disorder, panic disorder, eating disorder, or substance use disorder | 2 | [
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NCT02501096 | 9:25:cancer,27:32:cancer,36:71:cancer,76:108:cancer,112:118:cancer | treated melanoma in-situ, basal or squamous cell carcinoma of the skin, or carcinoma in-situ of the bladder or cervix | 2 | [
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NCT01189786 | 1:22:chronic_disease,,, | Pulmonary dysfunction (FEV1, FVC or DLCO 40% of predicted or 3 SD below normal) | 2 | [
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NCT02533674 | 1:16:treatment,22:52:treatment,75:91:treatment,, | Prior treatment with gemcitabine-containing therapy for advanced disease (adjuvant therapy is allowed, provided not more than six cycles were administered and relapse occurred more than six months after the last drug administration) | 2 | [
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NCT02324582 | 1:12:chronic_disease | Hepatitis C (e.g., HCV RNA [qualitative] is detected) | 2 | [
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NCT02013154 | 1:10:treatment,16:37:treatment,54:63:treatment, | Treatment with low dose chemotherapy concurrent with radiation within 14 days prior to study entry | 2 | [
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NCT02833792 | 12:28:chronic_disease | History of seizure disorder | 2 | [
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NCT02064036 | 8:19:treatment,35:45:treatment,47:52:treatment, | Use of dutasteride or dutasteride/tamsulosin (Jalyn) within 90 days prior to registration | 2 | [
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NCT02240498 | 1:10:chronic_disease | abscesses not amenable to safe percutaneous image-guided drainage | 2 | [
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NCT02774421 | 13:28:chronic_disease | significant cardiac disease | 2 | [
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NCT02383927 | 13:31:chronic_disease | Subject has measurable disease according to RECIST v1.1 | 2 | [
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NCT01495637 | 1:28:chronic_disease,30:55:cancer,,124:130:allergy_name | Autoimmune thrombocytopenia, myelodysplastic syndromes with > 20% marrow blast cells, or known allergy/hypersensitivity to GM-CSF | 2 | [
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NCT03095118 | 27:52:treatment,63:79:treatment,81:84:treatment,86:98:treatment,100:110:treatment,114:126:treatment, | Patients who had received immunosuppressive therapy including cyclophosphamide, MMF, cyclosporine, tacrolimus or azathioprine in the last 3 months | 2 | [
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NCT02913495 | 23:45:allergy_name | A contraindication to progesterone treatment | 2 | [
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NCT02459769 | 62:68:cancer | For caregivers, be currently undergoing active treatment for cancer | 2 | [
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NCT01829360 | 50:53:chronic_disease,61:67:chronic_disease,69:93:chronic_disease,95:111:chronic_disease | other disorder that would exclude a diagnosis of SLI (e.g., autism, developmental disability, seizure disorder) | 2 | [
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NCT02635893 | 78:97:chronic_disease,106:121:chronic_disease,123:135:chronic_disease,139:162:chronic_disease | Ongoing cord compression or a syrinx in the spinal cord or who suffer from a spinal cord disease such as spinal stenosis, spina bifida or herniated cervical disk | 2 | [
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NCT02264236 | 27:44:treatment | Subjects who have been on systemic steroids will require a 6-week washout period | 2 | [
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NCT01415752 | 22:32:cancer,59:83:cancer,85:111:cancer, | No evidence of prior malignancy except adequately treated non-melanoma skin cancer, in situ cervical carcinoma, or any surgically or radiation-cured malignancy continuously disease free for ≥ 5 years so as not to interfere with interpretation of radiographic response | 2 | [
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NCT02217709 | 1:42:treatment | Post-primary androgen-deprivation therapy | 2 | [
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NCT01464034 | 44:55:treatment | Pts who have received prior treatment with carfilzomib (Phase II only) | 2 | [
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NCT01532687 | 45:59:chronic_disease | History of any one or more of the following cardiovascular conditions | 2 | [
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NCT02184520 | 21:43:treatment,47:67:treatment,,86:93:treatment | Participation in an investigational device or drug clinical trials within 30 days of surgery | 2 | [
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NCT02271711 | 40:46:cancer | patient must have presented with these tumors in the posterior fossa (PF) or relapsed in the PF | 2 | [
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NCT01928576 | 16:26:treatment,28:39:treatment,45:54:treatment | The effects of entinostat, azacitidine, and Nivolumab, on the developing human fetus are unknown | 2 | [
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NCT02513485 | 1:26:treatment,28:39:treatment,48:67:treatment,69:85:treatment,106:120:chronic_disease | Embedded metallic objects, prosthetics made of paramagnetic metals, aneurysmal clips and/or a history of claustrophobia | 2 | [
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NCT02013492 | 32:38:cancer | the first 10 patients may have cancer of any histology | 2 | [
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NCT02341300 | ,,,,70:76:chronic_disease,,,, | Pregnant women of any age in their first trimester of pregnancy with anemia defined as a Hemoglobin less than 11 and/or a hematocrit less than 33 | 2 | [
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NCT03151330 | 27:45:treatment, | The subject has a planned cerclage placement for the current pregnancy | 2 | [
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NCT01903330 | 36:54:cancer | History, presence, or suspicion of metastatic disease | 2 | [
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