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NCT02393690
132:152:cancer
Modification of the RECIST v1.1 measurable disease criteria includes a change in the definition of what is considered a measurable malignant lymph node
2
[ "Modification", "of", "the", "RECIST", "v1.1", "measurable", "disease", "criteria", "includes", "a", "change", "in", "the", "definition", "of", "what", "is", "considered", "a", "measurable", "malignant", "lymph", "node" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 3, 3 ]
NCT02690116
26:32:chronic_disease
Currently diagnosed with anemia (fatigue-related factor)
2
[ "Currently", "diagnosed", "with", "anemia", "(", "fatigue-related", "factor", ")" ]
[ 0, 0, 0, 2, 0, 0, 0, 0 ]
NCT00969332
1:36:treatment
Extracorporeal Membrane Oxygenation
2
[ "Extracorporeal", "Membrane", "Oxygenation" ]
[ 1, 1, 1 ]
NCT02076906
34:50:chronic_disease
Clinically significant unrelated systemic illness
2
[ "Clinically", "significant", "unrelated", "systemic", "illness" ]
[ 0, 0, 0, 2, 2 ]
NCT02594111
1:10:treatment
ritonavir
2
[ "ritonavir" ]
[ 1 ]
NCT03096288
1:22:treatment
vitamin K antagonists
2
[ "vitamin", "K", "antagonists" ]
[ 1, 1, 1 ]
NCT02951455
7:27:chronic_disease,
Gross cognitive impairment as measured by the Mini Mental State Exam
2
[ "Gross", "cognitive", "impairment", "as", "measured", "by", "the", "Mini", "Mental", "State", "Exam" ]
[ 0, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02390752
,39:60:treatment,62:84:treatment,89:107:treatment,111:121:cancer
greater than or equal to 14 days from whole brain radiation, craniospinal radiation, or targeted radiation to CNS tumors
2
[ "greater", "than", "or", "equal", "to", "14", "days", "from", "whole", "brain", "radiation", ",", "craniospinal", "radiation", ",", "or", "targeted", "radiation", "to", "CNS", "tumors" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 1, 1, 1, 0, 1, 1, 0, 0, 1, 1, 0, 3, 3 ]
NCT02494869
1:27:chronic_disease
Uncontrolled heart failure
2
[ "Uncontrolled", "heart", "failure" ]
[ 2, 2, 2 ]
NCT02560766
12:50:chronic_disease,
History of suicidal behavior or suicidal ideation as indicated by the C-SSRS, administered at screening, and as per investigator's judgment
2
[ "History", "of", "suicidal", "behavior", "or", "suicidal", "ideation", "as", "indicated", "by", "the", "C-SSRS", ",", "administered", "at", "screening", ",", "and", "as", "per", "investigator", "'s", "judgment" ]
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NCT02387905
25:40:chronic_disease
Patients who have frank mechanical pain
2
[ "Patients", "who", "have", "frank", "mechanical", "pain" ]
[ 0, 0, 0, 0, 2, 2 ]
NCT00875342
9:32:chronic_disease
Current organic mental disorder
2
[ "Current", "organic", "mental", "disorder" ]
[ 0, 2, 2, 2 ]
NCT02484404
7:25:chronic_disease,36:55:chronic_disease,60:74:chronic_disease,116:125:treatment,131:145:treatment
Prior cardiac arrhythmia including atrial fibrillation and atrial flutter, or requiring concurrent use of drugs or biologics with pro-arrhythmic potential
2
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[ 0, 2, 2, 0, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0 ]
NCT02826577
1:14:chronic_disease
schizophrenia
2
[ "schizophrenia" ]
[ 2 ]
NCT02390752
65:83:treatment
Patients must have relapsed after or be refractory to effective standard therapies
2
[ "Patients", "must", "have", "relapsed", "after", "or", "be", "refractory", "to", "effective", "standard", "therapies" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 1 ]
NCT02481245
22:33:treatment
Agrees not to change medications during the study
2
[ "Agrees", "not", "to", "change", "medications", "during", "the", "study" ]
[ 0, 0, 0, 0, 1, 0, 0, 0 ]
NCT02132598
,,87:102:treatment
The subject has not recovered to baseline or CTCAE ≤ Grade 1 from toxicity due to all prior therapies
2
[ "The", "subject", "has", "not", "recovered", "to", "baseline", "or", "CTCAE", "≤", "Grade", "1", "from", "toxicity", "due", "to", "all", "prior", "therapies" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 1 ]
NCT02408861
48:57:treatment,62:65:chronic_disease,62:75:chronic_disease,87:113:treatment
Participants MUST receive appropriate care and treatment for HIV infection, including antiretroviral medications when clinically indicated, and should be under the care of a physician experienced in HIV management
2
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NCT01421095
1:24:treatment
unilateral oophorectomy
2
[ "unilateral", "oophorectomy" ]
[ 1, 1 ]
NCT02074436
1:17:cancer,,
Thrombocytopenia with untransfused platelet counts < 20 x 10⁹/L in the out-patient or in the in-patient setting
2
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NCT02779556
1:22:chronic_disease
cognitive impairments
2
[ "cognitive", "impairments" ]
[ 2, 2 ]
NCT02369770
1:32:chronic_disease
Severe cardiovascular disorders that interfere with ability to perform moderate movement exercises
2
[ "Severe", "cardiovascular", "disorders", "that", "interfere", "with", "ability", "to", "perform", "moderate", "movement", "exercises" ]
[ 2, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02480114
14:24:treatment
Currently on gabapentin
2
[ "Currently", "on", "gabapentin" ]
[ 0, 0, 1 ]
NCT02235857
1:20:chronic_disease,42:53:chronic_disease,55:70:chronic_disease,72:110:chronic_disease,115:131:chronic_disease
Cardiac impairments such as uncontrolled arrhyth¬mia, unstable angina, decompensated congestive heart failure, or valvular disease
2
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[ 2, 2, 0, 0, 0, 2, 0, 2, 2, 0, 2, 2, 2, 2, 0, 0, 2, 2 ]
NCT02775162
47:62:treatment,64:78:treatment,80:97:treatment,99:124:treatment
requiring all of the following at the time of transplantation: oxygen therapy, inotropic support, renal replacement therapy
2
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NCT01627301
1:10:treatment,16:27:treatment,76:85:treatment,87:100:treatment,102:116:treatment
treatment with medications known to affect the sympathetic nervous system (clonidine, beta blockers, ACE inhibitors)
2
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NCT01787682
8:64:treatment,
Use of protein or amino acid containing nutritional supplements within 5 days of first study day
2
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[ 0, 0, 1, 1, 1, 1, 1, 1, 1, 0, 0, 0, 0, 0, 0, 0 ]
NCT02496585
,44:65:chronic_disease
Newly diagnosed clinical grade 2 or higher radiation pneumonitis according to CTCAE version 4.0 criteria
2
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[ 0, 0, 0, 0, 0, 0, 0, 2, 2, 0, 0, 0, 0, 0, 0 ]
NCT02516670
10:28:treatment,33:51:cancer,55:91:cancer,116:141:cancer,
Have had prior chemotherapy for metastatic disease in castration-resistant prostate cancer (prior chemotherapy for hormone-sensitive disease, more than twelve months prior to registration, is acceptable)
2
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NCT00871260
1:41:chronic_disease
Acute ST-elevation myocardial infarction
2
[ "Acute", "ST-elevation", "myocardial", "infarction" ]
[ 2, 2, 2, 2 ]
NCT01505569
1:15:cancer
Hepatoblastoma - metastatic at time of diagnosis and/or relapsed after therapy
2
[ "Hepatoblastoma", "-", "metastatic", "at", "time", "of", "diagnosis", "and/or", "relapsed", "after", "therapy" ]
[ 3, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02926248
,41:60:treatment
Patients with less than 10 degrees of a flexion contracture
2
[ "Patients", "with", "less", "than", "10", "degrees", "of", "a", "flexion", "contracture" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 1, 1 ]
NCT02261519
15:35:treatment,
The subject's anti-EPS medications dose or regimen has changed within 2 weeks prior to screening
2
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NCT02594501
,,52:58:chronic_disease,62:77:chronic_disease,81:87:chronic_disease,96:106:chronic_disease,131:151:treatment,168:187:chronic_disease,,,
Patients older than age 18 with ischemic symptoms (stable or unstable angina or NSTEMI without thrombosis of the target lesion on coronary angiography) or evidence of myocardial ischemia in the presence of ≥ 50% de novo stenosis located in native coronary vessels (max. 2 lesions in one or 2 separate vessels)
2
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NCT01787409
1:33:cancer
Enteropathy-type T-cell lymphoma
2
[ "Enteropathy-type", "T-cell", "lymphoma" ]
[ 3, 3, 3 ]
NCT02454010
9:26:chronic_disease,
Serious cardiac condition within the last 6 months
2
[ "Serious", "cardiac", "condition", "within", "the", "last", "6", "months" ]
[ 0, 2, 2, 0, 0, 0, 0, 0 ]
NCT03096886
1:39:treatment
Centrally acting antiadrenergic agents
2
[ "Centrally", "acting", "antiadrenergic", "agents" ]
[ 1, 1, 1, 1 ]
NCT01791543
8:32:treatment,70:80:chronic_disease,93:97:chronic_disease
Failed prior VT or PVC ablation due to spontaneous recurrence of the arrhythmia or frequent PVCs
2
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NCT01876511
31:50:treatment,52:72:treatment,74:84:treatment,105:127:treatment,129:153:treatment,161:186:treatment,205:229:treatment,
received any of the following concomitant therapy: Interleukin-2 (IL-2), interferon, or other non-study immunotherapy regimens, immunosuppressive agents, other investigational therapies or chronic use of systemic corticosteroids within one week prior to first dose of study drug
2
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NCT00075387
35:71:chronic_disease
Subjects with rapidly progressing central nervous system (CNS) disease with associated neurological deterioration
2
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NCT01591356
49:55:cancer
this may be one of the lesions mentioned above; tumors within a previously irradiated field will be designated as 'non-target' lesions
2
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NCT02962557
11:14:chronic_disease,,,
Suspected OSA will be defined as a patient with a screening questionnaire (STOP-Bang) score of 5-8 (A score consistent with a high risk of OSA)
2
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NCT01696734
,,84:95:treatment,
have a negative urine pregnancy test within 30 days of the first administration of domperidone and must either commit to continued abstinence from heterosexual intercourse or use an effective method of birth control during the course of the study)
2
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NCT03181516
1:10:treatment
Cefoxitin
2
[ "Cefoxitin" ]
[ 1 ]
NCT01619761
1:35:cancer,78:87:treatment,113:122:treatment,145:152:treatment
Acute lymphoblastic leukemia (ALL): induction failure, primary refractory to treatment (do not achieve complete remission after first course of therapy) or are beyond first remission including second or greater remission or active disease
2
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NCT02526511
15:33:cancer,52:69:treatment,77:99:treatment,185:194:treatment
Patients with metastatic disease may have received prior nephrectomy and/or prior systemic therapy (no limit on number); their baseline pMRI would be performed prior to starting a new treatment
2
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NCT01312857
1:30:treatment
Prior treatment with HAI FUDR
2
[ "Prior", "treatment", "with", "HAI", "FUDR" ]
[ 1, 1, 1, 1, 1 ]
NCT03034564
1:10:treatment
modafinil
2
[ "modafinil" ]
[ 1 ]
NCT01988246
,,71:87:treatment
Central subfield macular thickness ≤ 320 μm in the study eye prior to cataract surgery as determined by SD-OCT and confirmed by the reading center
2
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NCT01882153
,41:48:chronic_disease
medically unstable (e.g., more than one seizure a month)
2
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[ 0, 0, 0, 0, 0, 0, 0, 0, 2, 0, 0, 0 ]
NCT02555280
1:11:chronic_disease,43:53:chronic_disease,157:196:treatment
Osteopenia: A screening questionnaire for osteopenia, SCORE (Simple Calculated Osteoporosis Risk Estimation), will be used to screen patients who require a DEXA (dual-energy x-ray absorptiometry) bone mineral density measurement
2
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NCT02106598
13:36:cancer
oral cavity squamous cell carcinoma
2
[ "oral", "cavity", "squamous", "cell", "carcinoma" ]
[ 0, 0, 3, 3, 3 ]
NCT03154476
1:25:chronic_disease
Severe renal dysfunction
2
[ "Severe", "renal", "dysfunction" ]
[ 2, 2, 2 ]
NCT02251431
27:37:allergy_name
Allergy or intolerance to gadolinium
2
[ "Allergy", "or", "intolerance", "to", "gadolinium" ]
[ 0, 0, 0, 0, 4 ]
NCT02481765
16:41:chronic_disease
The subject is severely hearing impaired
2
[ "The", "subject", "is", "severely", "hearing", "impaired" ]
[ 0, 0, 0, 2, 2, 2 ]
NCT02072356
1:30:chronic_disease
Active uncontrolled infection
2
[ "Active", "uncontrolled", "infection" ]
[ 2, 2, 2 ]
NCT02169037
1:25:chronic_disease
structural heart disease of clinical significance
2
[ "structural", "heart", "disease", "of", "clinical", "significance" ]
[ 2, 2, 2, 0, 0, 0 ]
NCT02500381
21:30:treatment,46:68:treatment,81:92:treatment,
Current or previous treatment with any other experimental treatment (other than deflazacort) within 12 weeks prior to Week 1
2
[ "Current", "or", "previous", "treatment", "with", "any", "other", "experimental", "treatment", "(", "other", "than", "deflazacort", ")", "within", "12", "weeks", "prior", "to", "Week", "1" ]
[ 0, 0, 0, 1, 0, 0, 0, 1, 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT03059888
26:32:cancer
Subject has a history of cancer in the last 5 years
2
[ "Subject", "has", "a", "history", "of", "cancer", "in", "the", "last", "5", "years" ]
[ 0, 0, 0, 0, 0, 3, 0, 0, 0, 0, 0 ]
NCT01861106
1:14:chronic_disease
HIV infection
2
[ "HIV", "infection" ]
[ 2, 2 ]
NCT01986205
1:15:chronic_disease
Claustrophobia precluding chamber or hood tolerance
2
[ "Claustrophobia", "precluding", "chamber", "or", "hood", "tolerance" ]
[ 2, 0, 0, 0, 0, 0 ]
NCT02567266
,,145:161:chronic_disease,169:197:chronic_disease,199:212:chronic_disease,214:230:chronic_disease,232:259:chronic_disease,264:283:chronic_disease,291:316:chronic_disease,318:348:chronic_disease,357:376:chronic_disease
Evidence of clinically significant symptoms will be defined as a Clinical Severity Rating (CSR) greater than or equal to 4 on any DSM-5 defined anxiety disorder (e.g., generalized anxiety disorder, social phobia, selective mutism, separation anxiety disorder) or depressive disorder (e.g., major depressive disorder, per...
2
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NCT02273362
1:9:treatment,34:46:treatment,50:69:treatment
Surgical cohort (cohort A only): percutaneous or transjugular biopsy incomplete or not performed
2
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NCT02070549
1:42:treatment,12:21:treatment,27:42:treatment,121:134:treatment,192:204:chronic_disease,251:263:chronic_disease
Concurrent treatment with bisphosphonates is permitted; however, treatment must be initiated prior to the first dose of study therapy; prophylactic use of bisphosphonates in patients without bone disease is not permitted, except for the treatment of osteoporosis
2
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NCT00819208
143:149:cancer
Able (i.e., sufficiently fluent) and willing to effectively communicate with the physical activity consultant affiliated with the originating cancer center
2
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NCT02535312
31:40:treatment
Arm A dose level 4 (75 mg/m^2 cisplatin)
2
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NCT02454517
35:55:chronic_disease
Doctor of medicine (MD) confirmed cognitive impairment
2
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NCT01625923
62:72:treatment,83:91:treatment,93:102:treatment,104:111:treatment,113:126:treatment,128:139:treatment,156:166:treatment,183:199:treatment,201:209:treatment,214:230:treatment,277:284:treatment,288:297:treatment
Subjects who are taking drugs that potentially interact with olanzapine including diazepam, lorazepam, alcohol, carbamazepine, fluvoxamine, olanzapine and fluoxetine in combination, CNS acting drugs, levodopa and dopamine agonist, and olanzapine when used in combination with lithium or valproate
2
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NCT01737502
1:26:cancer
localized prostate cancer
2
[ "localized", "prostate", "cancer" ]
[ 3, 3, 3 ]
NCT02046330
,93:108:treatment,
Adequate trials (equal or >6 weeks at the maximum recommended or tolerated dose) of primary antidepressants from at least 3 different classes
2
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NCT02423525
31:75:treatment
Current or anticipated use of enzyme-inducing anti-epileptic drugs (EIAED)
2
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NCT02496208
1:25:chronic_disease
Cardiovascular disorders
2
[ "Cardiovascular", "disorders" ]
[ 2, 2 ]
NCT02374021
54:79:chronic_disease
Prior patient reported, physician diagnosed clinical cardiovascular (CV) event
2
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NCT02743494
16:43:cancer
Diagnosed with Stage IV resectable disease
2
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[ 0, 0, 3, 3, 3, 3 ]
NCT01584076
12:51:treatment
history of prior amblyopia treatment with patching
2
[ "history", "of", "prior", "amblyopia", "treatment", "with", "patching" ]
[ 0, 0, 1, 1, 1, 1, 1 ]
NCT03028831
1:20:treatment
previous GI surgery resulting in disturbed gut function due to of loss of bowel or altered anatomy
2
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NCT02324439
1:9:treatment,66:79:chronic_disease,81:116:chronic_disease,118:127:chronic_disease,129:143:chronic_disease,147:152:chronic_disease,154:183:chronic_disease
Flaxseed supplementation may be contraindicated in patients with acute abdomen, esophageal stricture or perforation, dysphagia, GI obstruction or ileus, acute intestinal inflammation or unexplained abdominal pain. Patients with any of these conditions will be excluded from this trial as the high fiber content of flaxse...
2
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NCT02479698
89:98:chronic_disease
Persisting fever without other signs or symptoms will not be interpreted as progressing infection
2
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NCT01572480
16:26:chronic_disease,60:86:chronic_disease,91:106:treatment
Has refractory GI disease with refractory nausea/vomiting, inflammatory bowel disease, or bowel resection that would prevent absorption
2
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NCT01059786
30:39:chronic_disease
Presence of active untreated infection
2
[ "Presence", "of", "active", "untreated", "infection" ]
[ 0, 0, 0, 0, 2 ]
NCT03166371
1:22:chronic_disease,,,,,,
Acute hepatic failure during current hospitalization with total serum bilirubin > 3.5 mg/dL or transaminase values [alanine transaminase (ALT) and/or aspartate transaminase (AST) values > 3-fold the upper limit of normal range]
2
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NCT01464164
1:4:chronic_disease
DBA diagnosed
2
[ "DBA", "diagnosed" ]
[ 2, 0 ]
NCT02407808
1:17:chronic_disease
Hearing deficits
2
[ "Hearing", "deficits" ]
[ 2, 2 ]
NCT02646930
13:62:treatment
Patients on monoclonal antibody preparations directed to TNFα
2
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[ 0, 0, 1, 1, 1, 1, 1, 1 ]
NCT02994043
55:76:chronic_disease,88:111:chronic_disease,113:127:chronic_disease,133:142:chronic_disease
Currently taking any medications for the treatment of psychiatric disorders, including substance use disorders, mood disorders, and psychosis
2
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NCT02041936
19:31:treatment,36:52:treatment,,89:98:treatment,108:124:treatment
Inability to stop antiplatelet and coumadin therapy for 7 days prior to and 7 days post treatment with the NanoKnife System
2
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NCT01851369
11:17:cancer,
Any other cancer from which the patient has been disease-free for three years
2
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NCT02863809
48:62:treatment
No or minimal tear production with evidence of keratinization of the bulbar conjunctiva
2
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[ 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0 ]
NCT02151175
19:27:chronic_disease,57:74:chronic_disease,90:110:chronic_disease
Subjects who have seizures secondary to drugs, alcohol, metabolic illness or progressive degenerative disease
2
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NCT02163434
117:134:chronic_disease,136:148:chronic_disease,150:163:chronic_disease,168:188:chronic_disease
Felt by the patient's obstetrician or emergency room attending physician not to have other medical problems such as bowel obstruction, pancreatitis, biliary colic, or peptic ulcer disease that could be contributing to the patient's symptoms
2
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NCT02332187
18:26:treatment,,,,
Use of high dose pressors (more than 15 mcg/min of norepinephrine or more than 15 mg/kg/min of dopamine)
2
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NCT02321501
17:33:treatment
Able to swallow oral medications
2
[ "Able", "to", "swallow", "oral", "medications" ]
[ 0, 0, 0, 1, 1 ]
NCT01584076
7:29:chronic_disease
Known psychological problems
2
[ "Known", "psychological", "problems" ]
[ 0, 2, 2 ]
NCT02025465
9:36:chronic_disease,,
Current Atrioventricular (AV) block (2nd or 3rd degree)
2
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[ 0, 2, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT01962415
1:8:chronic_disease
Chediak
2
[ "Chediak" ]
[ 2 ]
NCT03113695
1:31:chronic_disease
fungal infections of nail beds
2
[ "fungal", "infections", "of", "nail", "beds" ]
[ 2, 2, 2, 2, 2 ]
NCT02124772
,,61:75:treatment,120:138:chronic_disease,139:147:chronic_disease
abnormal cardiac valve morphology (>=grade 2) documented by echocardiogram (subjects with grade 1 abnormalities [i.e., mild regurgitation/stenosis]
2
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NCT02944825
,,115:128:chronic_disease
We anticipated enrolling a study population of approximately 60% men and 40% women based on a higher incidence of kidney stones among men in NHANES data
2
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NCT02822001
,54:70:treatment
Patients weighing ≥ 80 pounds who are not -intubated prior to surgery
2
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NCT00903266
24:30:chronic_disease
right-handed (prior to stroke)
2
[ "right-handed", "(", "prior", "to", "stroke", ")" ]
[ 0, 0, 0, 0, 2, 0 ]