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NCT01676259 | 8:27:chronic_disease,37:54:chronic_disease,60:69:chronic_disease,,,157:171:treatment | Severe chronic obstructive or other pulmonary disease with hypoxemia (requires supplementary oxygen, symptoms due to hypoxemia or oxygen saturation <90% by pulse oximetry after a 2 minute walk) or in the opinion of the investigator any physiological state likely to cause systemic or regional hypoxemia | 2 | [
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NCT01910818 | 6:32:chronic_disease,24:32:chronic_disease,37:51:chronic_disease, | with radiation-induced fibrosis and depigmentation. The fibrosis must have occurred at least 1 year prior to the date of enrollment | 2 | [
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NCT03139227 | 20:68:treatment, | Chronic use of any herbal or dietary supplement containing apigenin within the 3 months prior to entry on the study | 2 | [
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NCT02013154 | 1:48:treatment,50:100:treatment,217:230:treatment,327:333:treatment | Prior treatment anti- programmed death-1 (PD-1)/ anti-PD-ligand 1 (PD-L1) monoclonal antibody (mAb) is permitted in patients provided the patient's disease is primary refractory, and the patient is not intolerant of pembrolizumab. Patients who are not eligible to receive pembrolizumab will be allowed to receive single ... | 2 | [
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NCT02131467 | 1:10:treatment | modafinil | 2 | [
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NCT02881515 | 1:8:chronic_disease,, | obesity (BMI > 30 kg/m2) | 2 | [
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NCT02446210 | 41:50:chronic_disease,52:66:chronic_disease,70:88:chronic_disease | Uncontrolled medical problems including pulmonary, cardiovascular or orthopedic disease | 2 | [
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NCT02920086 | 1:20:chronic_disease | respiratory failure episode within the preceding year; forced expiratory volume in 1 sec <0.5 L | 2 | [
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NCT02553161 | 1:5:chronic_disease | PTSD | 2 | [
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NCT02555280 | 45:76:treatment | Subject is currently involved in a study of another investigational product for similar purpose | 2 | [
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NCT02013154 | 1:46:treatment | Previously treated with an anti-DKK-1 therapy | 2 | [
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NCT02299414 | 7:13:chronic_disease | Prior stroke | 2 | [
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NCT02410954 | 17:75:chronic_disease | Current or past Axis I Diagnostic and Statistical Manual (DSM-IV) disorder based on the MINI | 2 | [
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NCT03005574 | 1:17:chronic_disease | medical disorder with known effects on cognitive functioning | 2 | [
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NCT02568267 | 27:33:cancer | History of other previous cancer that would interfere with the determination of safety or efficacy | 2 | [
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NCT02561104 | 14:30:treatment | Referred for cataract surgery at Parkland Memorial Hospital | 2 | [
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NCT02638454 | ,,,,,,158:176:chronic_disease,, | 10 subjects with Normal Muscle Mass and 10 subjects with Low Muscle Mass as determined by DXA scan (70-85 years of age cohort) Low Muscle Mass is defined as Class I Sarcopenia, Skeletal Muscle Index within 1 to 2 standard deviations from the sex-specific mean of young adults | 2 | [
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NCT02402088 | 25:42:chronic_disease,51:63:chronic_disease,65:79:chronic_disease,81:90:chronic_disease,92:97:chronic_disease,99:104:chronic_disease,106:123:chronic_disease,137:148:treatment | Any significant current medical condition such as neurological, cardiovascular, endocrine, renal, liver, thyroid pathology; subjects on medications for any medical condition | 2 | [
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NCT03181867 | 20:54:treatment | Subjects receiving androgen deprivation therapy (ADT) | 2 | [
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NCT01822522 | 1:22:chronic_disease,24:34:treatment,36:46:treatment | Gastrointestinal (GI): cimetidine, aprepitant | 2 | [
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NCT01620216 | 1:20:chronic_disease | Uncontrolled angina at time of consent OR | 2 | [
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NCT02752191 | 25:28:chronic_disease | with known or suspected CHD with inconclusive echocardiographic exams | 2 | [
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NCT01947140 | 68:83:cancer | Patients must have histologically confirmed relapsed or refractory T-Cell Lymphoma (as defined by WHO criteria) | 2 | [
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NCT03005782 | 1:31:treatment | Prior treatment with any LAG-3 targeting biologic or small molecule | 2 | [
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NCT02498535 | 17:31:treatment, | For subjects on cycled therapy, at least 2 cycles of drug need to have been completed prior to baseline | 2 | [
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NCT02552953 | ,14:32:treatment,,47:58:treatment,63:74:treatment,78:91:treatment,93:128:treatment,130:147:treatment | 4 weeks from prior chemotherapy ( 6 weeks for mitomycin C and nitrosourea) , immunotherapy, investigational anti-cancer therapy, radiation therapy; and have recovered from prior toxicities | 2 | [
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NCT01901562 | 6:32:chronic_disease | Have bilateral nipple discharge | 2 | [
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NCT01925131 | 37:49:treatment,51:73:treatment,88:101:treatment, | Patients must not have received any chemotherapy, investigational agents, or undergone major surgery within 14 days prior to registration | 2 | [
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NCT03037879 | 10:28:chronic_disease | Level of Spinal Cord Injury between C1 and T12 | 2 | [
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NCT02476786 | 1:19:chronic_disease | Measurable disease defined as lesions that can be accurately measured in at least one dimension (longest diameter to be recorded) by ultrasound or mammogram | 2 | [
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NCT01365169 | 16:22:cancer,35:59:cancer | History of any cancer, other than non-melanoma skin cancer (Arm 4) | 2 | [
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NCT02927301 | 5:34:treatment, | Any prior therapy for lung cancer within 3 years | 2 | [
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NCT02046330 | 33:36:treatment | Refusal of an adequate trial of ECT | 2 | [
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NCT01996865 | 33:48:allergy_name | Known sensitivity or allergy to murine products | 2 | [
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NCT02451488 | ,92:114:treatment,116:128:treatment,132:154:treatment | WOCBP include any female who has experienced menarche and who has not undergone successful surgical sterilization (hysterectomy or bilateral oophorectomy) or is not postmenopausal | 2 | [
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NCT02353728 | 1:26:chronic_disease,32:45:chronic_disease,46:65:chronic_disease | Right bundle branch block plus left anterior/posterior hemiblock | 2 | [
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NCT02881320 | 11:16:chronic_disease,,,,,,, | Cohort 3: HIV-1 infected children (≥ 2 years of age and screening weight of ≥ 14 to < 25 kg) who are virologically suppressed for ≥ 6 months prior to screening | 2 | [
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NCT02446236 | 14:21:treatment,,,46:75:treatment,112:140:treatment | Able to take aspirin (81 or 325 mg) daily as prophylactic anti-coagulation (patients intolerant to ASA may use low molecular weight heparin) | 2 | [
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NCT02762825 | 34:51:treatment,, | Referred by physician to CR with echocardiographic evidence of HFpEF defined as an ejection fraction ≥ 50 % | 2 | [
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NCT02327403 | ,17:32:treatment | ≥6 months after transplantation | 2 | [
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NCT02323880 | ,,,106:128:treatment | Antibodies: >= 21 days must have elapsed from infusion of last dose of antibody, and toxicity related to prior antibody therapy must be recovered to grade =< 1 | 2 | [
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NCT02232516 | 33:55:treatment,48:55:treatment,60:64:cancer,77:92:treatment, | Patients must not have received prior systemic therapy for PTCL (except for corticosteroids for 10 or fewer days at any dose, no washout period required as long as they discontinue prior to starting study therapy) | 2 | [
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NCT01829958 | 18:27:treatment,52:58:treatment,60:67:treatment,71:77:treatment,128:146:treatment | Intended initial treatment to include ≥2 cycles of R-CHOP, R-EPOCH or R-CEPP using standard doses and schedule.(68, 69) R-CHOP chemoimmunotherapy may be given every 14 days or every 21 days | 2 | [
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NCT01841333 | 28:32:treatment,61:85:cancer,101:115:treatment | High risk of relapse after HSCT, defined as the presence of minimal residual disease as measured by flow cytometry in the absence of evidence of morphologic disease on a bone marrow biopsy prior to HSCT | 2 | [
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NCT02792036 | 31:49:chronic_disease | Participants must not have an invasive infection at time of protocol entry | 2 | [
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NCT02081404 | 18:55:chronic_disease | oxygen dependent chronic obstructive pulmonary disease | 2 | [
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NCT02254863 | 16:35:treatment | Requirement of ventilatory support | 2 | [
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NCT02592707 | 1:19:chronic_disease | Measurable disease based on RECIST v1.1 | 2 | [
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NCT02573246 | 23:30:chronic_disease,86:107:chronic_disease,144:150:chronic_disease,173:183:treatment,223:233:treatment,235:243:treatment,245:253:treatment | Has increased risk of seizure for any reason, including prior diagnosis of increased intracranial pressure (such as after large infarctions or trauma), or currently taking medication that lowers the seizure threshold (e.g Wellbutrin, Adderall, Clozaril) | 2 | [
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NCT01967823 | 1:8:cancer,37:62:treatment,,107:116:treatment | Lesions that have been treated with stereotactic radiosurgery must be clinically stable for 1 month after treatment for the patient to be eligible | 2 | [
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NCT01953575 | 28:56:chronic_disease | Medical conditions such as severe heart or lung disease that preclude safe performance of endoscopy | 2 | [
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NCT01776190 | 59:70:treatment | You will need to participate in four physician visits and blood draws | 2 | [
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NCT02592551 | ,56:75:treatment | Any unresolved toxicity (>CTCAE grade 2) from previous anti-cancer therapy | 2 | [
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NCT02519452 | 1:19:chronic_disease, | Refractory disease is defined as less than (<) 25 percent (%) reduction in M-protein or progression of disease during treatment | 2 | [
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NCT02226159 | 73:76:treatment,77:79:treatment,92:110:chronic_disease | Deemed to be good operative candidates by spine surgeons (patients with MRI/CT findings of neural compression with concordant symptoms) and had agreed to possible operative intervention | 2 | [
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NCT02233868 | 1:16:treatment | antidepressants | 2 | [
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NCT00977977 | 1:34:chronic_disease,45:66:treatment,78:93:chronic_disease,95:98:chronic_disease,100:116:chronic_disease,118:132:chronic_disease,134:156:chronic_disease,158:168:chronic_disease | Active acute or chronic infection requiring antimicrobial therapy or serious viral infection (HIV, hepatitis B or C, herpes simplex, varicella zoster virus, parvovirus) | 2 | [
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NCT02338999 | ,47:56:treatment | Postmenopausal women who have not undergone a DEXA scan over the last year will undergo a DEXA scan at screening | 2 | [
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NCT02025426 | 23:44:chronic_disease | Any other physical or psychiatric condition which may impair their ability to cooperate with study data collection | 2 | [
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NCT02608840 | 10:41:chronic_disease | unstable medical or psychiatric disorder | 2 | [
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NCT02257138 | 16:33:chronic_disease,203:218:chronic_disease,229:246:chronic_disease | Any coexisting medical condition that in the judgment of the treating physician is likely to interfere with study procedures or results including uncontrolled severe infections, as well as uncontrolled cardiac disease, or other organ dysfunction | 2 | [
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NCT03143985 | 24:46:chronic_disease,74:120:chronic_disease,122:146:chronic_disease,164:179:chronic_disease,192:213:chronic_disease,217:223:chronic_disease,,288:299:chronic_disease | Clinically significant cardiovascular disease (e.g., uncontrolled or any New York Heart Association (NYHA) Class 3 or 4, congestive heart failure, uncontrolled or unstable angina, history of myocardial infarction or stroke within 6 months prior to study entry, or clinically significant arrhythmias not controlled by med... | 2 | [
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NCT02354703 | 8:19:treatment,, | Taking medications (within the last 7 days prior to the Baseline Visit) that have the potential to prolong the QT interval, as judged by a study physician, or may require such medications during the course of the study | 2 | [
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NCT02695433 | 13:19:cancer,31:55:cancer, | Have or had cancer other than non-melanoma skin cancer in past 5 years | 2 | [
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NCT02582775 | 29:31:chronic_disease,49:57:chronic_disease,59:66:chronic_disease,68:76:chronic_disease,78:85:chronic_disease,89:106:chronic_disease,111:171:treatment,175:216:treatment | Diagnosis of severe form of EB characterized by collagen, laminin, integrin, keratin or plakin deficiency (by immunofluorescence staining with protein specific antibodies or Western blotting and by mutation analysis) | 2 | [
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NCT02582775 | 13:36:cancer | Evidence of squamous cell carcinoma | 2 | [
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NCT02353819 | 60:83:treatment,87:111:treatment,114:128:treatment,133:143:treatment, | Clinically negative lymph nodes as established by imaging (abdominal and pelvic CT or abdominal and pelvic MRI), nodal sampling, or dissection within 90 days prior to registration | 2 | [
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NCT02479906 | 33:37:chronic_disease,, | Subjects with at least moderate PTSD with a CAPS-5 score ≥ 25 at both Screening and Baseline visits | 2 | [
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NCT02323191 | 23:35:treatment,37:49:treatment,61:82:treatment,94:107:treatment, | Prior toxicities from chemotherapy, radiotherapy, and other anti-cancer therapies, including immunotherapy that have not regressed to Grade <=1 severity (Common Terminology Criteria for Adverse Events [CTCAE] v4.03, or later versions) | 2 | [
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NCT03073343 | 13:26:chronic_disease,38:71:chronic_disease,75:104:chronic_disease | Evidence of liver disease other than non-alcoholic fatty liver disease or non-alcoholic steatohepatitis | 2 | [
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NCT01554371 | 1:25:chronic_disease,50:68:chronic_disease,103:124:chronic_disease,,168:179:treatment,245:260:chronic_disease | Congestive heart failure, Clinically significant cardiac arrhythmia, history or current evidence of a myocardial infarction during the last 6 months, and/or a current ECG tracing that is abnormal in the opinion of the treating Investigator, or unstable angina | 2 | [
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NCT02465268 | 1:4:chronic_disease,6:17:chronic_disease,22:33:chronic_disease | HIV, Hepatitis B, or Hepatitis C seropositive | 2 | [
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NCT03079297 | 6:31:chronic_disease | Have Maple Syrup Urine Disease | 2 | [
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NCT02424968 | ,,50:66:treatment | Patients must be beyond day 30 and before day 60 after transplant | 2 | [
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NCT01937884 | 25:44:treatment, | Anticipate placement of central venous line within 24 hours of admission | 2 | [
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