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NCT03153410 | 40:46:allergy_name,48:58:allergy_name,60:64:treatment,66:74:allergy_name,75:84:allergy_name,86:104:allergy_name,106:113:allergy_name,132:137:allergy_name,151:185:allergy_name | Known or suspected hypersensitivity to GM-CSF, hetastarch, corn, dimethyl sulfoxide, fetal bovine serum, trypsin (porcine origin), yeast or any other component of GVAX pancreas vaccine | 2 | [
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NCT02985554 | 15:39:cancer,47:66:treatment,111:115:chronic_disease,,148:163:chronic_disease | Patients with hematologic malignancies status post allogeneic SCT without evidence of disease relapse, active GVHD or history of more than Stage I skin acute GVHD | 2 | [
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NCT00881660 | 46:60:chronic_disease | Suspicion of major recognized syndrome (e.g. Fryns syndrome) on ultrasound or MRI | 2 | [
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NCT03115359 | 1:29:treatment | Cognitive Behavioral Therapy training | 2 | [
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NCT01760863 | 17:50:chronic_disease,92:115:treatment,97:115:treatment | Patients with a fungal prosthetic joint infection, unable to tolerate or refuse to undergo oral antibiotic therapy, unable to follow-up at the specified intervals, allergic to the therapy of preference, or have an organism that is not amenable to oral antibiotic therapy | 2 | [
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NCT02992275 | ,,66:84:chronic_disease, | Poorly controlled hypertension (>160/100); or patient report of: symptomatic angina at rest or during exercise, syncope without known resolution of cause, or a significant coronary event (such as a MI) in the past six months | 2 | [
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NCT01685411 | ,,,58:99:treatment | <45 years of age who are at least 6 months after initial hematopoietic stem cell transplant (HSCT) | 2 | [
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NCT02796391 | 22:41:chronic_disease | significant unstable medical/psychiatric or substance use disorders | 2 | [
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NCT01505569 | ,,61:74:chronic_disease | Cardiac: ejection fraction ≥ 45% or no clinical evidence of heart failure | 2 | [
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NCT02433977 | 1:7:chronic_disease, | Asthma-related ER visit within the previous 4 weeks | 2 | [
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NCT01972919 | 14:36:chronic_disease | Uncontrolled malabsorption syndrome significantly affecting gastrointestinal function | 2 | [
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NCT02324608 | 102:111:allergy_name | History of allergic reactions attributed to compounds of similar chemical or biologic composition to cetuximab or other agents used in the study | 2 | [
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NCT03110354 | 32:50:cancer,59:70:cancer,74:82:cancer,96:105:treatment | Has a second concurrent active primary malignancy such as solid tumor or lymphoma under active treatment | 2 | [
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NCT01827384 | 15:30:cancer,34:47:chronic_disease,51:87:treatment,89:98:treatment | Patients with bone metastases or hypercalcemia on intravenous bisphosphonate treatment, denosumab, or similar agents | 2 | [
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NCT02776891 | 16:26:treatment | intolerance to gadolinium | 2 | [
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NCT02533882 | 1:14:chronic_disease | Renal failure | 2 | [
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NCT02234557 | ,28:36:chronic_disease,38:52:chronic_disease,54:76:chronic_disease,78:95:chronic_disease | neurologic disorder (e.g., epilepsy, cerebral palsy, traumatic brain injury, Tourette Syndrome) | 2 | [
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NCT02593110 | 1:8:treatment,35:52:treatment,54:80:treatment | Surgery including lower extremity revascularization, coronary revascularization with stenting | 2 | [
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NCT03113760 | 33:54:treatment | Patients with genetic diagnosis of NLRC4-MAS mutation | 2 | [
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NCT02467478 | 10:24:chronic_disease,28:43:chronic_disease,,131:164:chronic_disease | Previous cardiovascular or cerebrovascular event within 6 months of screening or active or clinically significant coronary and/or Peripheral Vascular Disease (PVD) | 2 | [
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NCT02068092 | 1:28:treatment,21:28:treatment,,93:119:treatment | Prior anticoagulant therapy use is allowed provided therapy is discontinued at least 7 days prior to the breast biopsy in order to reduce the risk of bleeding | 2 | [
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NCT02172950 | ,,,61:84:chronic_disease,, | Males 0 to <18 years of who have been diagnosed with severe congenital hemophilia A (FVIII activity levels < 1%) | 2 | [
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NCT02522715 | 57:78:chronic_disease,80:103:chronic_disease,111:132:chronic_disease | clinical signs suggestive of high or imminent risks for pathological fracture, spinal cord compression and/or cauda equina syndrome | 2 | [
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NCT02538198 | ,,51:64:chronic_disease | New York Heart Association (NYHA) Class III or IV heart failure | 2 | [
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NCT01539109 | 1:9:chronic_disease | Dementia | 2 | [
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NCT02530034 | 30:38:treatment,42:67:treatment,78:100:cancer | Patients receiving any other standard or investigational treatment for their hematologic malignancy other than supportive care | 2 | [
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NCT01553071 | 62:72:cancer,131:139:treatment,143:162:treatment | Patients must have histologically or cytologically confirmed malignancy that is metastatic or unresectable and for which standard curative or palliative measures do not exist or are no longer effective | 2 | [
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NCT00904046 | 1:18:treatment, | Thiazolidinedione use in the preceding 18 months | 2 | [
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NCT00713492 | 25:56:treatment, | Daily or regular use of prescription or OTC medications known to interact with alcohol in the 2-week period prior to assessment | 2 | [
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NCT01742299 | 74:82:treatment,131:141:treatment,173:192:treatment | Patient has participated in a Novartis sponsored combination trial where imatinib was dispensed in combination with another study medication and patient is still receiving combination therapy | 2 | [
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NCT02143726 | 13:24:treatment | Concomitant medications | 2 | [
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NCT01505569 | 74:77:cancer,79:89:cancer,91:101:cancer,103:118:cancer,122:138:cancer,,,,,215:225:cancer | This would require a clinical situation consistent with the diagnosis of GCT (testicular, peritoneal, retroperitoneal or mediastinal mass, elevated tumor marker levels {HCG ≥ 500; AFP ≥ 500} and typical pattern of metastases) | 2 | [
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NCT02379156 | 1:26:chronic_disease | Untreated thyroid disease | 2 | [
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NCT01306045 | 36:47:treatment,57:86:treatment,203:232:treatment,,381:424:treatment,479:506:cancer,522:559:treatment,673:682:treatment | The eligibility of patients taking medications that are potent inducers or inhibitors of that enzyme will be determined following a review of their case by the Principal Investigator. (A list of potent CYP3A4 inducers or inhibitors can be found in Appendix F). Every effort should be made to switch patients taking such ... | 2 | [
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NCT01849146 | ,,53:70:treatment | Pregnant women are excluded from this study because AZD1775 (MK-1775) has potential for teratogenic or abortifacients effects | 2 | [
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NCT01954576 | 26:44:cancer,26:29:cancer,70:81:cancer,83:97:cancer,99:113:cancer,115:141:cancer,152:165:cancer,245:261:cancer | Histologically confirmed GBM (WHO grade IV); rare GBM variants (e.g. gliosarcoma, giant cell GBM, small cell GBM, GBM with oligodendroglioma features, GBM with PNET features) are allowed. Patients will be eligible if the original histology was low-grade glioma and a subsequent histological diagnosis of GBM is made | 2 | [
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NCT02488967 | 47:65:cancer, | Definitive clinical or radiologic evidence of metastatic disease; required imaging studies must have been performed within 90 days prior to randomization | 2 | [
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NCT02204098 | 20:49:treatment,74:84:treatment,96:129:treatment,131:148:treatment,153:175:treatment | Current use of any electronic stimulation device, such as cardiac demand pacemakers, automatic implantable cardiac defibrillator, nerve stimulators, or deep brain stimulators | 2 | [
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NCT02873598 | ,,82:103:treatment,123:133:treatment,137:148:treatment,153:167:treatment,, | Completion of at least 3 months, but no more than 6 months of standard induction chemotherapy for LAPC, which may include FOLFIRINOX or gemcitabine and nab-paclitaxel, preferably within 2-4 weeks but no longer than 8 weeks | 2 | [
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NCT02188745 | 15:43:cancer,,,,72:85:cancer,104:115:treatment | Patients with bone-only metastatic disease with a history of ER+/HER2- breast cancer are eligible, and bone biopsy is not required, providing their primary cancer is consistent with the above-described ER and HER2 criteria | 2 | [
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NCT02081404 | 13:44:chronic_disease,48:57:treatment,63:84:cancer | Presence of columnar lined distal esophagus on endoscopy with intestinal metaplasia | 3 | [
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NCT02290028 | 1:17:treatment,37:65:treatment,69:82:treatment,,141:149:treatment, | Cardiac surgical procedure, such as coronary artery bypass graft or valve surgery that is planned to occur within 6 months after implant or ablation that is planned to occur within 90 days after implant | 3 | [
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NCT02527681 | 39:49:treatment | Sufficient vascular access to receive study drug, and to allow blood sampling at a site separate from the study drug infusion site | 3 | [
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NCT00887146 | 7:14:cancer,57:67:cancer,71:100:cancer,117:122:cancer | mixed gliomas are eligible, regardless of the degree of astrocytic or oligodendrocytic predominance, as long as the tumor is also co-deleted for 1p and 19q | 3 | [
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NCT02163317 | 1:10:treatment, | Bone scan completed within 90 days | 3 | [
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NCT02493530 | 27:59:treatment | patients with exposure to other JAK-STAT inhibitory agents | 3 | [
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NCT02122172 | 35:90:treatment,41:68:treatment,94:111:cancer,213:240:treatment,255:269:treatment,273:291:treatment | All patients must have received a prior platinum-based chemotherapy regimen for treatment of urothelial cancer and must now be considered refractory to platinum-based chemotherapy; patients may have received the platinum-containing regimen either in the peri-operative or metastatic setting | 3 | [
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NCT02254863 | 1:19:chronic_disease | Chronic aspiration | 3 | [
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NCT02354703 | 64:71:chronic_disease | Subjects who are deemed by the PI or designee to be at risk of suicide | 3 | [
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NCT02178566 | 14:25:chronic_disease | Uncontrolled arrhythmias | 3 | [
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NCT02841540 | 31:34:cancer,35:39:cancer,62:91:treatment | Participants with higher-risk MDS/CMML must be intolerant of hypomethylating agents (HMAs) | 3 | [
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NCT02098161 | ,,,114:124:treatment, | Sexually active males must use a condom during intercourse while taking the drug and for 3 months after stopping study drug and should not father a child in this period; a condom is required to be used also by vasectomized men in order to prevent delivery of the drug via seminal fluid | 3 | [
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NCT01880567 | 21:24:cancer,, | Relapsed/refractory MCL: Absolute neutrophil count (ANC) >= 500/mm^3 | 3 | [
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NCT02400255 | 20:54:chronic_disease,63:80:chronic_disease,84:110:chronic_disease | Known positive for human immunodeficiency virus (HIV); active hepatitis B (HBV) or hepatitis C (HCV) infection | 3 | [
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NCT02479906 | 38:50:chronic_disease | Subject has a history of significant hearing loss | 3 | [
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NCT01553071 | ,,,118:128:treatment | For women of child-bearing potential, a negative serum pregnancy test is required within 72 hours prior to receiving study drug each cycle | 3 | [
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NCT02341300 | 24:30:chronic_disease,64:81:chronic_disease,83:102:chronic_disease,104:115:chronic_disease,117:124:chronic_disease | Any secondary cause of anemia including inherited and acquired hemolytic anemias (sickle cell disease, thalessemia, malaria, etc) Inability or unwillingness to try to use cast iron pot approximately 3x/week | 3 | [
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NCT02512718 | 10:27:chronic_disease | Unstable diabetes mellitus | 3 | [
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NCT02952365 | 15:36:chronic_disease | Subjects with ectatic eye disorders | 3 | [
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NCT01794793 | 87:103:treatment | Written informed consent obtained prior to enrolling in roll-over study and receiving study medication | 3 | [
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NCT03145298 | 19:26:chronic_disease | All patients with PAH-HIV must be on a stable and effective HAART combination regimen | 3 | [
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NCT02148796 | 51:55:chronic_disease | Participants may not have had more than two prior WLRI episodes | 3 | [
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NCT02429830 | ,19:32:chronic_disease,50:59:treatment,63:80:treatment | Presence of ˃3 cm hiatal hernia as determined by endoscopy or barium esophagram | 3 | [
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NCT02542202 | 1:16:chronic_disease,24:48:chronic_disease,59:74:treatment, | Unstable angina and/or congestive heart failure requiring hospitalization within the last 6 months prior to registration | 3 | [
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NCT01947673 | 1:22:chronic_disease | autonomic dysfunction | 3 | [
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NCT01697293 | 1:13:chronic_disease,21:52:cancer,70:90:treatment,109:118:treatment,122:135:cancer | osteoporosis, prior ductal carcinoma in situ [DCIS]), or who receive aromatase inhibitors for prevention or treatment of breast cancer, are eligible | 3 | [
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NCT02291523 | ,,35:53:chronic_disease | 7-21 who have been diagnosed with ulcerative colitis | 3 | [
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NCT01811368 | 13:28:chronic_disease | Symptomatic biliary disease | 3 | [
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NCT02633111 | 24:48:treatment,63:68:treatment,84:90:treatment,92:102:treatment | Recipient of frontline multi-agent chemotherapy (for example, RCHOP, dose adjusted-REPOCH, RCHOP/RICE, RCHOP+investigational agent, etc) | 3 | [
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NCT00492778 | 15:35:chronic_disease,49:54:treatment,58:84:treatment | Patients with ureteral obstruction must undergo stent or nephrostomy tube placement prior to study entry | 3 | [
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NCT02293096 | 21:31:allergy_name | hypersensitivity to metoprolol or its derivatives | 3 | [
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NCT00904046 | 13:24:chronic_disease | significant pedal edema | 3 | [
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NCT02076906 | 1:14:treatment | pegfilgrastim | 3 | [
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NCT02101944 | 1:16:treatment,7:16:treatment,,99:122:treatment, | Prior radiation is permitted; however, at least 2 weeks must have elapsed since the completion of prior radiation therapy and patients must have recovered from all radiation-associated toxicities to no greater than grade 1 at the time of registration | 3 | [
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NCT02633891 | 1:21:chronic_disease | Autonomic neuropathy as defined by the Toronto Diabetic Neuropathy Expert Group 2010/11 consensus criteria | 3 | [
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NCT02131467 | 1:21:treatment | Cognitive impairment | 3 | [
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NCT02138617 | 13:31:chronic_disease,47:59:chronic_disease,79:106:treatment | Evidence of bleeding diathesis or significant coagulopathy (in the absence of therapeutic anticoagulation) | 3 | [
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NCT02056873 | 26:33:chronic_disease, | Any attempt or intent of suicide in the last 6 months | 3 | [
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