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NCT02502708
,,93:121:chronic_disease
Patients with baseline QTc interval of more than 470 msec at study entry, and patients with congenital long QTc syndrome
3
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NCT03056339
15:18:chronic_disease,20:23:chronic_disease,25:28:chronic_disease,61:77:treatment,83:103:treatment
Patients with ALL, CLL, NHL with relapsed disease following standard therapy or a stem cell transplant
3
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NCT03110354
41:59:treatment
Has unresolved toxicities from previous anticancer therapy
3
[ "Has", "unresolved", "toxicities", "from", "previous", "anticancer", "therapy" ]
[ 0, 0, 0, 0, 0, 1, 1 ]
NCT02259621
45:73:chronic_disease,77:118:chronic_disease
Known positive history or positive test for Human Immunodeficiency Virus or Acquired ImmunoDeficiency Syndrome (AIDS)
3
[ "Known", "positive", "history", "or", "positive", "test", "for", "Human", "Immunodeficiency", "Virus", "or", "Acquired", "ImmunoDeficiency", "Syndrome", "(", "AIDS", ")" ]
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NCT02521493
35:61:chronic_disease,65:85:chronic_disease,103:144:treatment
Patients must have constitutional trisomy 21 (Down syndrome) or trisomy 21 mosaicism (by karyotype or fluorescence in situ hybridization [FISH])
3
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NCT02945436
38:55:chronic_disease
All participants must self-report as HIV sero-negative
3
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NCT00739362
,,,62:73:treatment
Weight less than 350 lbs, as this is the weight limit of the DXA machine
3
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NCT02389517
1:14:treatment,
Major surgery within 14 days before enrollment
3
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[ 1, 1, 0, 0, 0, 0, 0 ]
NCT02579265
1:14:chronic_disease
ileal atresia
3
[ "ileal", "atresia" ]
[ 2, 2 ]
NCT02493530
5:18:treatment,20:32:treatment,37:50:treatment,,84:104:treatment,
Any major surgery, chemotherapy, or immunotherapy within the last 21 days (limited palliative radiation is allowed ≥ 2 weeks)
3
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NCT02993406
29:35:allergy_name
Patient reported history of statin intolerance
3
[ "Patient", "reported", "history", "of", "statin", "intolerance" ]
[ 0, 0, 0, 0, 4, 0 ]
NCT01573429
7:25:chronic_disease
Known kidney dysfunction or disease
3
[ "Known", "kidney", "dysfunction", "or", "disease" ]
[ 0, 2, 2, 0, 0 ]
NCT02796209
1:26:chronic_disease
Impaired hepatic function
3
[ "Impaired", "hepatic", "function" ]
[ 2, 2, 2 ]
NCT02728050
,,191:210:chronic_disease
patient needs to be clinically stable as defined as being afebrile and hemodynamically stable for 24-48 hours prior to study day 0, unless fever is thought to be secondary to the underlying hematologic disease
3
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NCT02397889
62:73:treatment,75:97:chronic_disease,102:127:chronic_disease
history of difficulty with airway management during previous anesthetics, ischemic heart disease and uncontrolled hypertension
3
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NCT00739362
36:39:treatment,47:56:treatment,85:99:chronic_disease
Any conditions contraindicated for MRI (e.g., pacemaker, metal in body, significant claustrophobia)
3
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NCT01620216
3:70:chronic_disease
> New York Heart Association (NYHA) class II congestive heart failure at time of consent OR
3
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NCT03071692
27:35:treatment,39:74:treatment,80:92:treatment,
Current or planned use of fibrates or agents with PPAR-α agonist activity (eg, saroglitazar) within 6 weeks (42 days) of Visit 1 (Screening/Enrollment Visit)
3
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NCT02983240
21:30:treatment
A permanent cardiac pacemaker
3
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[ 0, 0, 0, 1 ]
NCT01220583
43:66:cancer,,129:139:treatment,166:172:treatment
Radiologic confirmation of the absence of hematogenous metastasis within 12 weeks prior to registration; at a minimum, contrast CT imaging of the chest is required (PET/CT is acceptable)
3
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NCT02343549
35:46:chronic_disease
documented clinically significant arrhythmias
3
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[ 0, 0, 0, 2 ]
NCT02356861
26:55:treatment
Not meeting criteria for post-traumatic stress disorder and for mild or moderate traumatic brain injury
3
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NCT03022292
28:39:allergy_name,41:56:allergy_name,58:81:allergy_name,83:92:allergy_name,94:122:allergy_name,124:142:allergy_name,147:167:allergy_name,174:191:allergy_name
Known serious allergies to aflibercept, fluorescein dye, Indocyanine Green (ICG), shellfish, drugs for pupillary dilation, topical anesthetic, or sterilizing solution (e.g. Betadine Solution)
3
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NCT02425904
33:36:chronic_disease,49:83:treatment,162:173:treatment,231:248:chronic_disease,267:293:treatment
Individuals who are known to be HIV-positive on combination antiretroviral therapy are ineligible because of the potential for pharmacokinetic interactions with clofarabine. In addition, these individuals are at increased risk of lethal infections when treated with marrow-suppressive therapy. Appropriate studies will b...
3
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NCT03182751
1:25:treatment,
Coronary stent placement within the previous 6 months
3
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NCT02108860
1:53:allergy_name
eosinophilic granulomatosis with polyangiitis (EGPA)
3
[ "eosinophilic", "granulomatosis", "with", "polyangiitis", "(", "EGPA", ")" ]
[ 4, 4, 4, 4, 4, 0, 0 ]
NCT02193490
12:19:chronic_disease,
Documented Dry Eye Disease for at least 6 months
3
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[ 0, 2, 2, 0, 0, 0, 0, 0, 0 ]
NCT02762266
1:24:cancer
dermatologic basal cell
3
[ "dermatologic", "basal", "cell" ]
[ 3, 3, 3 ]
NCT03058679
8:19:treatment,
Use of antibiotics (other than topical formulations) for any reason within 2 weeks prior to screening
3
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NCT02417701
,,,,,383:393:treatment
The effects of MLN0128 (TAK-228) on the developing human fetus are unknown; for this reason women of child-bearing potential and men must agree to practice 1 highly effective method of contraception and 1 additional effective (barrier) method, at the same time, prior to study through 90 days (or longer, as mandated by ...
3
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NCT02013154
,,,,,92:119:chronic_disease
Fridericia-corrected QT interval (QTcF) > 470 msec (female) or > 450 (male), or history of congenital long QT syndrome
3
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NCT02559817
,,148:156:treatment,158:169:treatment,174:179:treatment,
For at least 2 months before the Screening Visit, the patient has had 2 or fewer defecations (with each defecation occurring in the absence of any laxative, suppository, or enema use during the preceding 24 hours) in the toilet per week
3
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NCT02762266
1:19:treatment
Prior radiotherapy to the upper abdomen
3
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[ 1, 1, 0, 0, 0, 0 ]
NCT02362997
59:95:treatment
Participants must be planning to receive or have received autologous stem cell transplantation
3
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NCT02264236
35:57:chronic_disease
Existing diagnosis or evidence of organic brain syndrome that might preclude participation in the full protocol
3
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NCT02725177
37:44:chronic_disease
Persistent disease activity (active uveitis) at the time of screening
3
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NCT02265315
12:19:chronic_disease,12:20:chronic_disease,39:50:chronic_disease,123:135:chronic_disease,137:162:chronic_disease,164:181:treatment,183:208:treatment,225:238:chronic_disease,289:299:chronic_disease,313:338:treatment,342:354:treatment
History of seizures, history of major head trauma, metal objects implanted in the head, ferrous metal filings in the eye, brain damage, inflammation of the brain, cardiac pacemaker, implanted medication pump, cardiac lines, heart disease, currently taking certain types of medication for depression or seizures (tricycli...
3
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NCT02910700
18:69:chronic_disease
History of known glucose-6-phosphate dehydrogenase (G6PD) deficiency
3
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[ 0, 0, 0, 2, 2, 2, 2, 0, 0 ]
NCT02694029
,25:42:cancer
Women with diagnosis of breast malignancy
3
[ "Women", "with", "diagnosis", "of", "breast", "malignancy" ]
[ 0, 0, 0, 0, 3, 3 ]
NCT02764853
38:62:chronic_disease
Inability (e.g., due to cognitive or psychiatric difficulties) or unwillingness to provide informed consent
3
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[ 0, 0, 0, 0, 0, 0, 0, 0, 2, 2, 0, 0, 0, 0, 0, 0, 0 ]
NCT02122328
10:33:treatment
Abnormal intracranial ultrasound findings of either fetus to include
3
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[ 0, 1, 1, 0, 0, 0, 0, 0, 0 ]
NCT02481765
43:51:chronic_disease,53:63:chronic_disease,65:70:chronic_disease,72:86:chronic_disease,88:93:chronic_disease,95:113:chronic_disease,115:124:chronic_disease,126:145:chronic_disease,149:155:cancer
No previous or current medical history of epilepsy, neurologic, heart, endocrinologic, renal, chronic infectious, metabolic, psychiatric disease or cancer
3
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NCT01964859
22:32:allergy_name,34:46:allergy_name,48:60:allergy_name
subjects allergic to penicillin, streptomycin, amphotericin
3
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[ 0, 0, 0, 4, 0, 4, 0, 4 ]
NCT02403128
12:57:treatment,59:89:treatment,93:100:treatment,105:120:treatment,124:127:chronic_disease,
History of systemic or intravitreal anti-VEGF injections, intravitreal steroid injection or implant, or laser treatment to RAM within six months
3
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NCT03179085
11:20:chronic_disease,,
diagnosed diabetics or HbA1c >7
3
[ "diagnosed", "diabetics", "or", "HbA1c", ">", "7" ]
[ 0, 2, 0, 0, 0, 0 ]
NCT03073785
45:79:chronic_disease
patients with either initially diagnosed or recurrent locally advanced disease
3
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[ 0, 0, 0, 0, 0, 0, 2, 2, 2, 2 ]
NCT02013154
8:26:chronic_disease,45:63:treatment,,124:139:treatment,143:166:treatment
Active autoimmune disease that has required systemic treatment in past 2 years (i.e. with use of disease modifying agents, corticosteroids or immunosuppressive drugs)
3
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NCT02991144
,,115:129:chronic_disease,145:154:treatment,156:167:treatment,172:189:treatment
with documented diagnosis of late onset (defined as first manifestation of signs and symptoms at ≥1 month of age) OTC deficiency, confirmed via enzymatic, biochemical, or molecular testing
3
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NCT02457832
1:27:chronic_disease
Untreated Major Depression
3
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[ 2, 2, 2 ]
NCT02911116
8:23:chronic_disease,38:66:treatment,,116:125:treatment
Active chorioretinitis or leakage on Fluorescein angiography (FA)(that is in more than one quadrant) that requires treatment
3
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NCT02829268
12:49:chronic_disease,51:67:chronic_disease,76:94:chronic_disease
history of chronic obstructive pulmonary disease, pleural effusion, and/or myocardial disease
3
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[ 0, 0, 2, 2, 2, 2, 0, 2, 2, 0, 0, 2, 2 ]
NCT02339948
1:11:treatment
Prior TURP
3
[ "Prior", "TURP" ]
[ 1, 1 ]
NCT02555189
19:28:cancer,72:80:treatment,88:130:treatment,135:151:cancer
Clinically stable CNS tumor at the time of screening and not receiving steroids and/or enzyme-inducing anti-epileptic medications for brain metastases
3
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[ 0, 0, 3, 3, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 1, 1, 0, 3, 3 ]
NCT02495168
1:16:treatment
Oral β-blockers
3
[ "Oral", "β-blockers" ]
[ 1, 1 ]
NCT01872975
5:22:treatment,51:64:cancer,65:87:treatment
Any radiation therapy for the currently diagnosed breast cancer prior to randomization
3
[ "Any", "radiation", "therapy", "for", "the", "currently", "diagnosed", "breast", "cancer", "prior", "to", "randomization" ]
[ 0, 1, 1, 0, 0, 0, 0, 3, 3, 1, 1, 1 ]
NCT02132130
1:13:chronic_disease
Hearing loss due to any other cause that would not be expected to respond to hair cell regeneration
3
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[ 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02106312
1:38:treatment
Prior radiotherapy to the target area
3
[ "Prior", "radiotherapy", "to", "the", "target", "area" ]
[ 1, 1, 1, 1, 1, 1 ]
NCT02519543
14:24:chronic_disease
diagnosis of BD I or II
3
[ "diagnosis", "of", "BD", "I", "or", "II" ]
[ 0, 0, 2, 2, 2, 2 ]
NCT02259621
1:32:treatment,34:44:treatment,46:56:treatment,61:81:treatment
Prior therapy with an anti-PD-1, anti-PD-L1, anti-PDL-2, or anti-CTLA-4 antibody (or any other antibody targeting T cell co-regulatory pathways)
3
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NCT02403128
5:19:treatment,
Any ocular surgery during the preceding 3 months
3
[ "Any", "ocular", "surgery", "during", "the", "preceding", "3", "months" ]
[ 0, 1, 1, 0, 0, 0, 0, 0 ]
NCT02293109
23:35:cancer
Disease free of other malignancies
3
[ "Disease", "free", "of", "other", "malignancies" ]
[ 0, 0, 0, 0, 3 ]
NCT02769611
42:63:treatment,
(LVAD) left ventricular assist device or heart transplantation expected within the next 3 months
3
[ "(", "LVAD", ")", "left", "ventricular", "assist", "device", "or", "heart", "transplantation", "expected", "within", "the", "next", "3", "months" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 1, 1, 0, 0, 0, 0, 0, 0 ]
NCT03038269
21:41:treatment
Currently receiving intrathecal baclofen
3
[ "Currently", "receiving", "intrathecal", "baclofen" ]
[ 0, 0, 1, 1 ]
NCT01597518
,,,,32:36:treatment
Liver enzymes (ALT/SGPT or AST/SGOT) 3 times the upper limit of normal (ULN) at screening visit
3
[ "Liver", "enzymes", "(", "ALT/SGPT", "or", "AST/SGOT", ")", "3", "times", "the", "upper", "limit", "of", "normal", "(", "ULN", ")", "at", "screening", "visit" ]
[ 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02366481
20:44:treatment
Subjects receiving corticosteroid treatment
3
[ "Subjects", "receiving", "corticosteroid", "treatment" ]
[ 0, 0, 1, 1 ]
NCT02145260
1:24:chronic_disease,
Acute coronary syndrome within seven days
3
[ "Acute", "coronary", "syndrome", "within", "seven", "days" ]
[ 2, 2, 2, 0, 0, 0 ]
NCT01880567
1:24:cancer,10:24:cancer,,105:128:treatment
Relapsed/refractory MCL: Patient has relapsed and or refractory MCL and must have received at least one prior treatment regimen for their disease
3
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NCT02130687
1:23:chronic_disease
Secondary hypertension
3
[ "Secondary", "hypertension" ]
[ 2, 2 ]
NCT02215096
,,,135:154:chronic_disease
Must have a QT interval corrected for heart rate according to Fridericia's formula (QTcF) <470 milli seconds (msec) or <480 msec with bundle branch block
3
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NCT02109627
1:24:treatment,,67:89:treatment,,149:162:treatment,166:181:treatment,186:196:treatment
Prior induction therapy had to include no more than two cycles of cytotoxic chemotherapy and at least one induction cycle must have consisted of an anthracycline or anthracenedione and cytarabine combination with a reasonable schedule/dose according to the discretion of the investigator
3
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NCT02466750
7:24:treatment,7:34:treatment,47:77:treatment,79:116:treatment,118:129:treatment,131:152:treatment,154:179:treatment,181:193:treatment,195:233:treatment
Other immunosuppressive therapies include all cancer chemotherapeutic agents, drugs to prevent transplant rejection, interferons, monoclonal antibodies, protein kinase inhibitors, methotrexate, TNF (tumor necrosis factor) inhibitors, and any other drug determined to be immunosuppressive by the PI
3
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NCT03120585
1:18:chronic_disease
air leak syndrome
3
[ "air", "leak", "syndrome" ]
[ 2, 2, 2 ]
NCT02543944
73:79:treatment
fulfill Diagnostic Statistical Manual-V criteria for moderate to severe opioid dependence
3
[ "fulfill", "Diagnostic", "Statistical", "Manual-V", "criteria", "for", "moderate", "to", "severe", "opioid", "dependence" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0 ]
NCT02740543
1:32:chronic_disease
Allergic Asthma Population (AA)
3
[ "Allergic", "Asthma", "Population", "(", "AA", ")" ]
[ 2, 2, 2, 2, 0, 0 ]
NCT02313428
,54:65:treatment
Patient has received at least 2 weeks of appropriate antibiotics
3
[ "Patient", "has", "received", "at", "least", "2", "weeks", "of", "appropriate", "antibiotics" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 1 ]
NCT02542657
7:36:chronic_disease,40:52:treatment,83:98:treatment,115:126:treatment
Known gastrointestinal (GI) disease or GI procedure that could interfere with the oral absorption or tolerance of study drugs including difficulty swallowing
3
[ "Known", "gastrointestinal", "(", "GI", ")", "disease", "or", "GI", "procedure", "that", "could", "interfere", "with", "the", "oral", "absorption", "or", "tolerance", "of", "study", "drugs", "including", "difficulty", "swallowing" ]
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NCT02995590
63:66:treatment
Subjects with any implanted device that cannot be verified as MRI compliant
3
[ "Subjects", "with", "any", "implanted", "device", "that", "can", "not", "be", "verified", "as", "MRI", "compliant" ]
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NCT02592707
1:12:treatment,14:30:treatment,46:65:treatment,102:116:chronic_disease
Nephrectomy, renal transplant or concomitant nephrotoxic therapy putting the subject at high risk of renal toxicity during the study as assessed by the investigator
3
[ "Nephrectomy", ",", "renal", "transplant", "or", "concomitant", "nephrotoxic", "therapy", "putting", "the", "subject", "at", "high", "risk", "of", "renal", "toxicity", "during", "the", "study", "as", "assessed", "by", "the", "investigator" ]
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NCT02048722
10:18:treatment,,
Low dose warfarin (1 mg orally, once daily) with prothrombin time (PT)-international normalized ratio (INR) =< 1.5 x ULN is permitted
3
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NCT02903511
1:14:chronic_disease
Liver disease
3
[ "Liver", "disease" ]
[ 2, 2 ]
NCT02011971
35:50:chronic_disease,130:147:chronic_disease,,255:261:treatment
Subject has a lifetime history of suicide attempt (including an active attempt, interrupted attempt, or aborted attempt), or has suicidal ideation in the past 6 months as indicated by a positive response ('Yes') to either Question 4 or Question 5 of the C-SSRS at Screening
3
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NCT02564796
1:16:chronic_disease
Hepatic failure
3
[ "Hepatic", "failure" ]
[ 2, 2 ]
NCT02108860
10:26:treatment
Abnormal chest radiograph, defined as the presence of nodules, fixed infiltrates, or cavities
3
[ "Abnormal", "chest", "radiograph", ",", "defined", "as", "the", "presence", "of", "nodules", ",", "fixed", "infiltrates", ",", "or", "cavities" ]
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NCT02516969
1:19:treatment,,
Prior radiotherapy to a dose of ≥50Gy
3
[ "Prior", "radiotherapy", "to", "a", "dose", "of", "≥50Gy" ]
[ 1, 1, 0, 0, 0, 0, 0 ]
NCT01986205
31:63:treatment
Concomitant enrollment in any other drug/device clinical trial
3
[ "Concomitant", "enrollment", "in", "any", "other", "drug/device", "clinical", "trial" ]
[ 0, 0, 0, 0, 1, 1, 1, 1 ]
NCT02628535
1:15:chronic_disease,
diverticulitis within 4 weeks of first study drug administration
3
[ "diverticulitis", "within", "4", "weeks", "of", "first", "study", "drug", "administration" ]
[ 2, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT00904046
1:22:chronic_disease
Chronic liver disease
3
[ "Chronic", "liver", "disease" ]
[ 2, 2, 2 ]
NCT01712308
1:14:treatment,,
Major surgery within 4 weeks prior to day 1
3
[ "Major", "surgery", "within", "4", "weeks", "prior", "to", "day", "1" ]
[ 1, 1, 0, 0, 0, 0, 0, 0, 0 ]
NCT01835626
7:19:treatment,47:53:cancer,86:95:treatment,86:103:treatment
Prior radiotherapy to the region of the study cancer that would result in overlap of radiation therapy fields in such a way that curative intent with radiation cannot be met
3
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NCT02095678
,,108:143:chronic_disease
less than 30 mL/min/1.73 m2 based on patient's serum creatinine due to the significantly increased risk of nephrogenic systemic fibrosis (NSF)
3
[ "less", "than", "30", "mL/min/1.73", "m2", "based", "on", "patient", "'s", "serum", "creatinine", "due", "to", "the", "significantly", "increased", "risk", "of", "nephrogenic", "systemic", "fibrosis", "(", "NSF", ")" ]
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NCT01553071
86:104:chronic_disease,106:142:chronic_disease,144:168:chronic_disease,170:188:chronic_disease,190:211:chronic_disease
Uncontrolled intercurrent illnesses including, but not limited to, ongoing or active systemic infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, coagulation disorders
3
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NCT02169089
11:26:cancer
localized Prostate cancer
3
[ "localized", "Prostate", "cancer" ]
[ 0, 3, 3 ]
NCT02397083
7:42:chronic_disease,55:65:chronic_disease,113:128:treatment,154:169:treatment,191:207:treatment,222:247:treatment,270:292:chronic_disease,298:325:chronic_disease,355:373:chronic_disease,375:401:chronic_disease,428:451:chronic_disease
Known impairment of gastrointestinal (GI) function or GI disease that may significantly alter the absorption of oral everolimus (e.g., inability to take oral medication or a requirement for intravenous [IV] alimentation, prior surgical procedures affecting absorption, malabsorption syndrome, and active peptic ulcer dis...
3
[ "Known", "impairment", "of", "gastrointestinal", "(", "GI", ")", "function", "or", "GI", "disease", "that", "may", "significantly", "alter", "the", "absorption", "of", "oral", "everolimus", "(", "e.g.", ",", "inability", "to", "take", "oral", "medication", "or...
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NCT03158519
14:36:chronic_disease
uncontrolled psychiatric conditions
3
[ "uncontrolled", "psychiatric", "conditions" ]
[ 0, 2, 2 ]
NCT02070549
15:32:cancer,34:51:cancer,68:76:cancer,102:117:treatment
Patients with pancreatic cancer, colorectal cancer, and BRAF V600E melanoma patients who have failed BRAF inhibitors are allowed to enroll in the moderate and severe cohorts provided the patients: 1) sign a separate consent form which outlines the extremely limited activity observed in prior studies, and 2) are consent...
3
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NCT02530034
1:14:cancer,,,
myelofibrosis with high-risk features (e.g., accelerated phase disease -10-19% blasts in peripheral blood or bone marrow-, or with Dynamic International Prognostic Scoring System [DIPSS]-plus high risk score)
3
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NCT02577549
26:41:treatment,
Unwilling to discontinue pain medication use for 3 days prior to testing visit
3
[ "Unwilling", "to", "discontinue", "pain", "medication", "use", "for", "3", "days", "prior", "to", "testing", "visit" ]
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NCT01619761
50:69:chronic_disease
Have identified a backup cells source in case of engraftment failure; the source can be autologous, related or unrelated
3
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[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02496208
12:28:treatment
History of organ transplant
3
[ "History", "of", "organ", "transplant" ]
[ 0, 0, 1, 1 ]
NCT02891681
18:38:treatment
Prior history of chest wall radiation
3
[ "Prior", "history", "of", "chest", "wall", "radiation" ]
[ 0, 0, 0, 1, 1, 1 ]