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NCT02502708 | ,,93:121:chronic_disease | Patients with baseline QTc interval of more than 470 msec at study entry, and patients with congenital long QTc syndrome | 3 | [
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NCT03056339 | 15:18:chronic_disease,20:23:chronic_disease,25:28:chronic_disease,61:77:treatment,83:103:treatment | Patients with ALL, CLL, NHL with relapsed disease following standard therapy or a stem cell transplant | 3 | [
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NCT03110354 | 41:59:treatment | Has unresolved toxicities from previous anticancer therapy | 3 | [
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NCT02259621 | 45:73:chronic_disease,77:118:chronic_disease | Known positive history or positive test for Human Immunodeficiency Virus or Acquired ImmunoDeficiency Syndrome (AIDS) | 3 | [
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NCT02521493 | 35:61:chronic_disease,65:85:chronic_disease,103:144:treatment | Patients must have constitutional trisomy 21 (Down syndrome) or trisomy 21 mosaicism (by karyotype or fluorescence in situ hybridization [FISH]) | 3 | [
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NCT02945436 | 38:55:chronic_disease | All participants must self-report as HIV sero-negative | 3 | [
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NCT00739362 | ,,,62:73:treatment | Weight less than 350 lbs, as this is the weight limit of the DXA machine | 3 | [
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NCT02389517 | 1:14:treatment, | Major surgery within 14 days before enrollment | 3 | [
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NCT02579265 | 1:14:chronic_disease | ileal atresia | 3 | [
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NCT02493530 | 5:18:treatment,20:32:treatment,37:50:treatment,,84:104:treatment, | Any major surgery, chemotherapy, or immunotherapy within the last 21 days (limited palliative radiation is allowed ≥ 2 weeks) | 3 | [
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NCT02993406 | 29:35:allergy_name | Patient reported history of statin intolerance | 3 | [
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NCT01573429 | 7:25:chronic_disease | Known kidney dysfunction or disease | 3 | [
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NCT02796209 | 1:26:chronic_disease | Impaired hepatic function | 3 | [
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NCT02728050 | ,,191:210:chronic_disease | patient needs to be clinically stable as defined as being afebrile and hemodynamically stable for 24-48 hours prior to study day 0, unless fever is thought to be secondary to the underlying hematologic disease | 3 | [
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NCT02397889 | 62:73:treatment,75:97:chronic_disease,102:127:chronic_disease | history of difficulty with airway management during previous anesthetics, ischemic heart disease and uncontrolled hypertension | 3 | [
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NCT00739362 | 36:39:treatment,47:56:treatment,85:99:chronic_disease | Any conditions contraindicated for MRI (e.g., pacemaker, metal in body, significant claustrophobia) | 3 | [
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NCT01620216 | 3:70:chronic_disease | > New York Heart Association (NYHA) class II congestive heart failure at time of consent OR | 3 | [
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NCT03071692 | 27:35:treatment,39:74:treatment,80:92:treatment, | Current or planned use of fibrates or agents with PPAR-α agonist activity (eg, saroglitazar) within 6 weeks (42 days) of Visit 1 (Screening/Enrollment Visit) | 3 | [
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NCT02983240 | 21:30:treatment | A permanent cardiac pacemaker | 3 | [
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NCT01220583 | 43:66:cancer,,129:139:treatment,166:172:treatment | Radiologic confirmation of the absence of hematogenous metastasis within 12 weeks prior to registration; at a minimum, contrast CT imaging of the chest is required (PET/CT is acceptable) | 3 | [
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NCT02343549 | 35:46:chronic_disease | documented clinically significant arrhythmias | 3 | [
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NCT02356861 | 26:55:treatment | Not meeting criteria for post-traumatic stress disorder and for mild or moderate traumatic brain injury | 3 | [
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NCT03022292 | 28:39:allergy_name,41:56:allergy_name,58:81:allergy_name,83:92:allergy_name,94:122:allergy_name,124:142:allergy_name,147:167:allergy_name,174:191:allergy_name | Known serious allergies to aflibercept, fluorescein dye, Indocyanine Green (ICG), shellfish, drugs for pupillary dilation, topical anesthetic, or sterilizing solution (e.g. Betadine Solution) | 3 | [
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NCT02425904 | 33:36:chronic_disease,49:83:treatment,162:173:treatment,231:248:chronic_disease,267:293:treatment | Individuals who are known to be HIV-positive on combination antiretroviral therapy are ineligible because of the potential for pharmacokinetic interactions with clofarabine. In addition, these individuals are at increased risk of lethal infections when treated with marrow-suppressive therapy. Appropriate studies will b... | 3 | [
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NCT03182751 | 1:25:treatment, | Coronary stent placement within the previous 6 months | 3 | [
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NCT02108860 | 1:53:allergy_name | eosinophilic granulomatosis with polyangiitis (EGPA) | 3 | [
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NCT02193490 | 12:19:chronic_disease, | Documented Dry Eye Disease for at least 6 months | 3 | [
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NCT02762266 | 1:24:cancer | dermatologic basal cell | 3 | [
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NCT03058679 | 8:19:treatment, | Use of antibiotics (other than topical formulations) for any reason within 2 weeks prior to screening | 3 | [
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NCT02417701 | ,,,,,383:393:treatment | The effects of MLN0128 (TAK-228) on the developing human fetus are unknown; for this reason women of child-bearing potential and men must agree to practice 1 highly effective method of contraception and 1 additional effective (barrier) method, at the same time, prior to study through 90 days (or longer, as mandated by ... | 3 | [
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NCT02013154 | ,,,,,92:119:chronic_disease | Fridericia-corrected QT interval (QTcF) > 470 msec (female) or > 450 (male), or history of congenital long QT syndrome | 3 | [
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NCT02559817 | ,,148:156:treatment,158:169:treatment,174:179:treatment, | For at least 2 months before the Screening Visit, the patient has had 2 or fewer defecations (with each defecation occurring in the absence of any laxative, suppository, or enema use during the preceding 24 hours) in the toilet per week | 3 | [
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NCT02362997 | 59:95:treatment | Participants must be planning to receive or have received autologous stem cell transplantation | 3 | [
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NCT02264236 | 35:57:chronic_disease | Existing diagnosis or evidence of organic brain syndrome that might preclude participation in the full protocol | 3 | [
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NCT02725177 | 37:44:chronic_disease | Persistent disease activity (active uveitis) at the time of screening | 3 | [
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NCT02265315 | 12:19:chronic_disease,12:20:chronic_disease,39:50:chronic_disease,123:135:chronic_disease,137:162:chronic_disease,164:181:treatment,183:208:treatment,225:238:chronic_disease,289:299:chronic_disease,313:338:treatment,342:354:treatment | History of seizures, history of major head trauma, metal objects implanted in the head, ferrous metal filings in the eye, brain damage, inflammation of the brain, cardiac pacemaker, implanted medication pump, cardiac lines, heart disease, currently taking certain types of medication for depression or seizures (tricycli... | 3 | [
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NCT02910700 | 18:69:chronic_disease | History of known glucose-6-phosphate dehydrogenase (G6PD) deficiency | 3 | [
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NCT02764853 | 38:62:chronic_disease | Inability (e.g., due to cognitive or psychiatric difficulties) or unwillingness to provide informed consent | 3 | [
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NCT02481765 | 43:51:chronic_disease,53:63:chronic_disease,65:70:chronic_disease,72:86:chronic_disease,88:93:chronic_disease,95:113:chronic_disease,115:124:chronic_disease,126:145:chronic_disease,149:155:cancer | No previous or current medical history of epilepsy, neurologic, heart, endocrinologic, renal, chronic infectious, metabolic, psychiatric disease or cancer | 3 | [
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NCT01964859 | 22:32:allergy_name,34:46:allergy_name,48:60:allergy_name | subjects allergic to penicillin, streptomycin, amphotericin | 3 | [
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NCT03179085 | 11:20:chronic_disease,, | diagnosed diabetics or HbA1c >7 | 3 | [
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NCT03073785 | 45:79:chronic_disease | patients with either initially diagnosed or recurrent locally advanced disease | 3 | [
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NCT02991144 | ,,115:129:chronic_disease,145:154:treatment,156:167:treatment,172:189:treatment | with documented diagnosis of late onset (defined as first manifestation of signs and symptoms at ≥1 month of age) OTC deficiency, confirmed via enzymatic, biochemical, or molecular testing | 3 | [
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NCT02911116 | 8:23:chronic_disease,38:66:treatment,,116:125:treatment | Active chorioretinitis or leakage on Fluorescein angiography (FA)(that is in more than one quadrant) that requires treatment | 3 | [
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NCT02829268 | 12:49:chronic_disease,51:67:chronic_disease,76:94:chronic_disease | history of chronic obstructive pulmonary disease, pleural effusion, and/or myocardial disease | 3 | [
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NCT02555189 | 19:28:cancer,72:80:treatment,88:130:treatment,135:151:cancer | Clinically stable CNS tumor at the time of screening and not receiving steroids and/or enzyme-inducing anti-epileptic medications for brain metastases | 3 | [
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NCT02495168 | 1:16:treatment | Oral β-blockers | 3 | [
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NCT01872975 | 5:22:treatment,51:64:cancer,65:87:treatment | Any radiation therapy for the currently diagnosed breast cancer prior to randomization | 3 | [
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NCT02106312 | 1:38:treatment | Prior radiotherapy to the target area | 3 | [
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NCT02519543 | 14:24:chronic_disease | diagnosis of BD I or II | 3 | [
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NCT02259621 | 1:32:treatment,34:44:treatment,46:56:treatment,61:81:treatment | Prior therapy with an anti-PD-1, anti-PD-L1, anti-PDL-2, or anti-CTLA-4 antibody (or any other antibody targeting T cell co-regulatory pathways) | 3 | [
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NCT02403128 | 5:19:treatment, | Any ocular surgery during the preceding 3 months | 3 | [
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NCT02769611 | 42:63:treatment, | (LVAD) left ventricular assist device or heart transplantation expected within the next 3 months | 3 | [
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NCT03038269 | 21:41:treatment | Currently receiving intrathecal baclofen | 3 | [
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NCT01597518 | ,,,,32:36:treatment | Liver enzymes (ALT/SGPT or AST/SGOT) 3 times the upper limit of normal (ULN) at screening visit | 3 | [
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NCT02366481 | 20:44:treatment | Subjects receiving corticosteroid treatment | 3 | [
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NCT02145260 | 1:24:chronic_disease, | Acute coronary syndrome within seven days | 3 | [
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NCT01880567 | 1:24:cancer,10:24:cancer,,105:128:treatment | Relapsed/refractory MCL: Patient has relapsed and or refractory MCL and must have received at least one prior treatment regimen for their disease | 3 | [
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NCT02130687 | 1:23:chronic_disease | Secondary hypertension | 3 | [
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NCT02215096 | ,,,135:154:chronic_disease | Must have a QT interval corrected for heart rate according to Fridericia's formula (QTcF) <470 milli seconds (msec) or <480 msec with bundle branch block | 3 | [
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NCT02109627 | 1:24:treatment,,67:89:treatment,,149:162:treatment,166:181:treatment,186:196:treatment | Prior induction therapy had to include no more than two cycles of cytotoxic chemotherapy and at least one induction cycle must have consisted of an anthracycline or anthracenedione and cytarabine combination with a reasonable schedule/dose according to the discretion of the investigator | 3 | [
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NCT02466750 | 7:24:treatment,7:34:treatment,47:77:treatment,79:116:treatment,118:129:treatment,131:152:treatment,154:179:treatment,181:193:treatment,195:233:treatment | Other immunosuppressive therapies include all cancer chemotherapeutic agents, drugs to prevent transplant rejection, interferons, monoclonal antibodies, protein kinase inhibitors, methotrexate, TNF (tumor necrosis factor) inhibitors, and any other drug determined to be immunosuppressive by the PI | 3 | [
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NCT02543944 | 73:79:treatment | fulfill Diagnostic Statistical Manual-V criteria for moderate to severe opioid dependence | 3 | [
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NCT02740543 | 1:32:chronic_disease | Allergic Asthma Population (AA) | 3 | [
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NCT02313428 | ,54:65:treatment | Patient has received at least 2 weeks of appropriate antibiotics | 3 | [
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NCT02542657 | 7:36:chronic_disease,40:52:treatment,83:98:treatment,115:126:treatment | Known gastrointestinal (GI) disease or GI procedure that could interfere with the oral absorption or tolerance of study drugs including difficulty swallowing | 3 | [
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NCT02995590 | 63:66:treatment | Subjects with any implanted device that cannot be verified as MRI compliant | 3 | [
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NCT02592707 | 1:12:treatment,14:30:treatment,46:65:treatment,102:116:chronic_disease | Nephrectomy, renal transplant or concomitant nephrotoxic therapy putting the subject at high risk of renal toxicity during the study as assessed by the investigator | 3 | [
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NCT02048722 | 10:18:treatment,, | Low dose warfarin (1 mg orally, once daily) with prothrombin time (PT)-international normalized ratio (INR) =< 1.5 x ULN is permitted | 3 | [
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NCT02903511 | 1:14:chronic_disease | Liver disease | 3 | [
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NCT02011971 | 35:50:chronic_disease,130:147:chronic_disease,,255:261:treatment | Subject has a lifetime history of suicide attempt (including an active attempt, interrupted attempt, or aborted attempt), or has suicidal ideation in the past 6 months as indicated by a positive response ('Yes') to either Question 4 or Question 5 of the C-SSRS at Screening | 3 | [
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NCT02628535 | 1:15:chronic_disease, | diverticulitis within 4 weeks of first study drug administration | 3 | [
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NCT00904046 | 1:22:chronic_disease | Chronic liver disease | 3 | [
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NCT01712308 | 1:14:treatment,, | Major surgery within 4 weeks prior to day 1 | 3 | [
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NCT01835626 | 7:19:treatment,47:53:cancer,86:95:treatment,86:103:treatment | Prior radiotherapy to the region of the study cancer that would result in overlap of radiation therapy fields in such a way that curative intent with radiation cannot be met | 3 | [
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NCT02095678 | ,,108:143:chronic_disease | less than 30 mL/min/1.73 m2 based on patient's serum creatinine due to the significantly increased risk of nephrogenic systemic fibrosis (NSF) | 3 | [
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NCT01553071 | 86:104:chronic_disease,106:142:chronic_disease,144:168:chronic_disease,170:188:chronic_disease,190:211:chronic_disease | Uncontrolled intercurrent illnesses including, but not limited to, ongoing or active systemic infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, coagulation disorders | 3 | [
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NCT02169089 | 11:26:cancer | localized Prostate cancer | 3 | [
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NCT02397083 | 7:42:chronic_disease,55:65:chronic_disease,113:128:treatment,154:169:treatment,191:207:treatment,222:247:treatment,270:292:chronic_disease,298:325:chronic_disease,355:373:chronic_disease,375:401:chronic_disease,428:451:chronic_disease | Known impairment of gastrointestinal (GI) function or GI disease that may significantly alter the absorption of oral everolimus (e.g., inability to take oral medication or a requirement for intravenous [IV] alimentation, prior surgical procedures affecting absorption, malabsorption syndrome, and active peptic ulcer dis... | 3 | [
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NCT03158519 | 14:36:chronic_disease | uncontrolled psychiatric conditions | 3 | [
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NCT02070549 | 15:32:cancer,34:51:cancer,68:76:cancer,102:117:treatment | Patients with pancreatic cancer, colorectal cancer, and BRAF V600E melanoma patients who have failed BRAF inhibitors are allowed to enroll in the moderate and severe cohorts provided the patients: 1) sign a separate consent form which outlines the extremely limited activity observed in prior studies, and 2) are consent... | 3 | [
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NCT02530034 | 1:14:cancer,,, | myelofibrosis with high-risk features (e.g., accelerated phase disease -10-19% blasts in peripheral blood or bone marrow-, or with Dynamic International Prognostic Scoring System [DIPSS]-plus high risk score) | 3 | [
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NCT02577549 | 26:41:treatment, | Unwilling to discontinue pain medication use for 3 days prior to testing visit | 3 | [
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NCT01619761 | 50:69:chronic_disease | Have identified a backup cells source in case of engraftment failure; the source can be autologous, related or unrelated | 3 | [
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NCT02496208 | 12:28:treatment | History of organ transplant | 3 | [
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NCT02891681 | 18:38:treatment | Prior history of chest wall radiation | 3 | [
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