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NCT02353819
|
13:35:treatment,47:54:treatment,56:67:treatment,69:109:treatment,115:127:treatment
|
Concomitant antineoplastic therapy (including surgery, cryotherapy, conventionally fractionated radiotherapy, and chemotherapy) while on this protocol
| 3
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NCT00977977
|
22:31:chronic_disease,35:63:chronic_disease,94:106:treatment
|
Clinical evidence of cirrhosis or chronic active liver disease sufficiently severe to impair cyclosporine metabolism; this would include a prolonged prothrombin time
| 3
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NCT01522768
|
30:39:treatment,
|
May have previously received lapatinib as part of a regimen in the perioperative or metastatic setting with evidence of progression of disease. Washout period for lapatinib of 14 days
| 3
|
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NCT02587403
|
25:28:treatment
|
Planned use of external VAC dressing intra-operatively
| 3
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NCT01626079
|
1:35:chronic_disease,
|
Percutaneous coronary intervention within 30 days prior to subject registration
| 3
|
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NCT00293475
|
27:39:treatment
|
eligible for reduced dose methotrexate
| 3
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NCT02408120
|
15:37:chronic_disease
|
Subjects with acute critical illness admitted to the ICU or expected to require ICU admission
| 3
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NCT02046330
|
18:25:chronic_disease
|
Imminent risk of suicide
| 3
|
[
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0,
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NCT02000115
|
1:13:treatment
|
Aortic valve is a congenital unicuspid or congenital bicuspid valve, or is non-calcified as verified by echocardiography
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NCT02478268
|
44:47:treatment
|
does not fit into 129Xe vest coil used for MRI
| 3
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NCT01099644
|
1:14:treatment,,63:79:treatment,84:97:treatment
|
Prior Therapy: At least 4 weeks should have elapsed since any biologic therapy, or immunotherapy
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NCT02628535
|
77:94:cancer
|
Histologically and/or cytologically proven unresectable locally advanced or metastatic tumors that express B7-H3 on the membrane or vasculature
| 3
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NCT02304458
|
19:31:cancer
|
For patients with solid tumors without known bone marrow involvement
| 3
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NCT02849457
|
12:20:chronic_disease,24:40:chronic_disease,69:92:chronic_disease,113:116:treatment
|
History of seizures or infantile spasms, or evidence of subclinical electrographic seizures on a previous video EEG
| 3
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NCT02087826
|
12:25:chronic_disease,,,
|
History of liver disease and/or aspartate aminotransferase (AST) or alanine aminotransferase (ALT) more than 3 times upper limit of normal (ULN)
| 3
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NCT02451423
|
1:4:chronic_disease,15:32:chronic_disease,34:37:chronic_disease,,149:160:chronic_disease
|
HIV or active hepatitis B virus (HBV; chronic or acute; defined as having a positive hepatitis B surface antigen [Bag] test at screening) or active hepatitis C
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NCT01917929
|
31:62:treatment
|
Patient requires simultaneous bilateral total hip replacement
| 3
|
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NCT02969577
|
15:18:treatment
|
Re-initiating ADT after being on holiday for longer than their ADT dosage
| 3
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NCT02067975
|
16:44:treatment,46:75:treatment,77:85:treatment,91:107:treatment
|
Treatment with monoamine oxidase inhibitors, migraine headache medications (triptans) and dextromethorphan
| 3
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NCT02526511
|
1:33:chronic_disease,,,182:217:chronic_disease,238:280:treatment
|
Severe renal function impairment (estimated glomerular filtration rate [eGFR] < 45 mL/min/1.73 m^2) would make the patient inappropriate for enrollment due to the increased risk of nephrogenic systemic fibrosis (NSF) with higher dose of IV gadolinium-based contrast agents (GBCA) administration
| 3
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NCT02446236
|
25:36:chronic_disease
|
History of uncontrolled arrhythmias
| 3
|
[
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[
0,
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NCT01585402
|
14:31:chronic_disease,
|
Longstanding diabetes mellitus (more than 10 years)
| 3
|
[
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NCT02272998
|
21:47:cancer
|
Patients with acute hematological malignancies
| 3
|
[
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"malignancies"
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0,
0,
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3,
3
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NCT02983240
|
7:23:chronic_disease
|
Frank chorioamnionitis
| 3
|
[
"Frank",
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] |
[
0,
2
] |
NCT02907983
|
1:15:treatment
|
sham treatment
| 3
|
[
"sham",
"treatment"
] |
[
1,
1
] |
NCT02981082
|
1:28:treatment,,,,,,,,
|
Right heart catheterization demonstrating mPAP≥ 25 mmHg and PCWP or left ventricular end diastolic pressure ≤15mm Hg and pulmonary vascular resistance ≥240 dynes/cm-5 (3 Wood units) within 12 weeks prior to study entry
| 3
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NCT01876511
|
28:48:chronic_disease,97:106:chronic_disease,119:143:chronic_disease,145:169:chronic_disease,171:189:chronic_disease,193:214:chronic_disease
|
Patients with uncontrolled intercurrent illness, including but not limited to ongoing or active infection, systematic congestive heart failure, unstable angina pectoris, cardiac arrhythmia or psychiatric condition that would limit compliance with study requirements
| 3
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NCT03003390
|
12:15:chronic_disease
|
History of HIT (i.e., positive serotonin release assay)
| 3
|
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NCT02040610
|
4:22:treatment
|
No prior radiotherapy to the pelvic area
| 3
|
[
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[
0,
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0,
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0
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NCT02589340
|
,,40:50:treatment,61:70:treatment,74:101:chronic_disease
|
Currently taking between 200-500 mg of amantadine daily for treatment of levodopa-induced dyskinesia with insufficient suppression levodopa-induced dyskinesia
| 3
|
[
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NCT02122328
|
10:26:chronic_disease,,,
|
Isolated ventriculomegaly (atrium 10-19 mm) may or may not be used
| 3
|
[
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NCT02352467
|
1:6:chronic_disease,14:16:chronic_disease,45:53:chronic_disease,55:65:chronic_disease,78:88:chronic_disease,90:115:chronic_disease,117:123:chronic_disease,128:136:chronic_disease
|
Ulcer not of PU pathophysiology (e.g., pure diabetic, vasculitic, radiation, rheumatoid, collagen vascular disease, venous, or arterial etiology)
| 3
|
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NCT02940288
|
1:26:treatment
|
Anticoagulant medications
| 3
|
[
"Anticoagulant",
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[
1,
1
] |
NCT02516670
|
38:53:cancer,,,186:201:cancer,339:358:cancer,388:407:treatment,506:524:treatment
|
Have metastatic castration-resistant prostate cancer (prostate cancer progressing despite castrate levels of testosterone [< 50 ng/dL] using standard measures of progression defined by Prostate Cancer Working Group 2), are chemo-naïve for metastatic castration-resistant prostate cancer (mCRPC); patients must have symptomatic disease or visceral metastases or otherwise be eligible for docetaxel treatment per investigator judgment (e.g. for progression on imaging or rapidly rising PSA despite 2nd line hormonal treatment)
| 3
|
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NCT02589977
|
22:62:treatment
|
contraindications to cardiac magnetic resonance imaging (CMR)
| 3
|
[
"contraindications",
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"cardiac",
"magnetic",
"resonance",
"imaging",
"(",
"CMR",
")"
] |
[
0,
0,
1,
1,
1,
1,
1,
0,
0
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NCT02592707
|
39:50:chronic_disease,74:90:chronic_disease,92:116:chronic_disease,118:136:chronic_disease,156:168:chronic_disease,188:205:chronic_disease,,,232:256:chronic_disease
|
Any uncontrolled significant medical, psychiatric or surgical condition (active infection, unstable angina pectoris, cardiac arrhythmia, poorly controlled hypertension, poorly controlled diabetes mellitus [HbA1c ≥9%], uncontrolled congestive heart disease, etc.) or laboratory findings that, in the opinion of the investigator, might jeopardize the patient's safety or that would limit compliance with the objectives and assessments of the study
| 3
|
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NCT00799864
|
19:38:treatment,
|
Use of disallowed concomitant therapy from 4 weeks prior to the baseline visit
| 3
|
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NCT02424968
|
14:21:chronic_disease
|
asymptomatic viremia
| 3
|
[
"asymptomatic",
"viremia"
] |
[
0,
2
] |
NCT01989585
|
14:65:chronic_disease
|
A history of glucose-6-phosphate dehydrogenase (G6PD) deficiency
| 3
|
[
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2,
2,
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0,
0
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NCT02304458
|
47:67:cancer
|
Part B6: patients with relapsed or refractory non-Hodgkin lymphoma
| 3
|
[
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0,
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NCT02389309
|
64:76:cancer,,,
|
The patient must have a stable clinical (neurologic in case of brain tumors) exam and be on a stable dose of steroids for at least 1 week prior to study entry; the patient should have a measurable and/or evaluable disease; measurable disease which is defined as the presence of at least one lesion that can be accurately measured in two dimensions (each measures at least 10 mm) or evaluable disease which is defined as at least one lesion that can be accurately measured in at least one dimension (measure at least 10 mm)
| 3
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NCT02512926
|
,,85:93:cancer,97:114:cancer,115:127:treatment
|
the plt and ANC requirements can be waived if low counts thought to be secondary to leukemia or tumor bone marrow infiltration
| 3
|
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NCT01599559
|
36:51:chronic_disease,103:126:chronic_disease,128:152:chronic_disease
|
Evidence of clinically significant cardiac disease at diagnosis, as defined by history of symptomatic ventricular arrhythmias, congestive heart failure
| 3
|
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NCT02982759
|
1:26:chronic_disease
|
major psychiatric illness
| 3
|
[
"major",
"psychiatric",
"illness"
] |
[
2,
2,
2
] |
NCT01917929
|
39:60:treatment
|
Patient has previously undergone open surgical intervention on the operative hip
| 3
|
[
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0,
0,
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NCT01555905
|
25:52:chronic_disease
|
No clinical evidence of impaired pulmonary function
| 3
|
[
"No",
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"evidence",
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"pulmonary",
"function"
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[
0,
0,
0,
0,
2,
2,
2
] |
NCT02048722
|
27:38:treatment,
|
Major surgical procedure, open biopsy, or significant traumatic injury within 28 days before registration
| 3
|
[
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NCT02321735
|
1:50:cancer,
|
stage III/IV high grade epithelial ovarian cancer diagnosed at least 10 years ago
| 3
|
[
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"epithelial",
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"cancer",
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NCT03120728
|
1:9:chronic_disease,15:26:chronic_disease,27:38:chronic_disease,39:49:chronic_disease,59:75:chronic_disease,
|
diabetes with nephropathy/retinopathy/neuropathy or other vascular disease diagnosed more than 20 years ago
| 3
|
[
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"vascular",
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"diagnosed",
"more",
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[
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2,
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NCT00147056
|
16:39:treatment,47:56:treatment,77:83:treatment
|
who are not on anti seizure medication (e.g., Phenytoin 100 mg PO t.i.d. or Keppra 500 mg po bid) before the procedure
| 3
|
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NCT02044120
|
8:38:chronic_disease
|
Active central nervous system disease
| 3
|
[
"Active",
"central",
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"system",
"disease"
] |
[
0,
2,
2,
2,
2
] |
NCT02286687
|
,,87:117:treatment,119:163:treatment,,,196:220:cancer
|
Aspartate aminotransferase (AST) (serum glutamic oxaloacetic transaminase [SGOT]) and alanine aminotransferase (ALT) (serum glutamate pyruvate transaminase [SGPT]) =< 2.5 x ULN (or =< 5 x ULN if liver metastases [mets])
| 3
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NCT02838797
|
1:31:chronic_disease
|
Idiopathic Parkinson's Disease (UK Brain Bank Criteria)
| 3
|
[
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NCT01626079
|
,,47:57:treatment
|
Severe symptomatic carotid stenosis (> 70% by ultrasound)
| 3
|
[
"Severe",
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"stenosis",
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"70",
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[
0,
0,
0,
0,
0,
0,
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0,
0,
1,
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NCT02462161
|
13:31:chronic_disease
|
Significant neurologic disease that might affect cognition
| 3
|
[
"Significant",
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"disease",
"that",
"might",
"affect",
"cognition"
] |
[
0,
2,
2,
0,
0,
0,
0
] |
NCT02581982
|
8:26:chronic_disease,45:63:treatment,,102:126:treatment,128:143:treatment,147:170:treatment,173:192:treatment,199:208:treatment,210:217:treatment,222:268:treatment,273:280:chronic_disease,284:307:chronic_disease
|
Active autoimmune disease that has required systemic treatment in the past 2 years (i.e. with use of disease modifying agents, corticosteroids or immunosuppressive drugs); replacement therapy (eg., thyroxine, insulin, or physiologic corticosteroid replacement therapy for adrenal or pituitary insufficiency, etc.) is not considered a form of systemic treatment
| 3
|
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NCT02776891
|
1:10:treatment,,
|
Prior MRI with gadolinium performed <24 hours before the study scan
| 3
|
[
"Prior",
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NCT00924027
|
1:16:cancer
|
Prostate cancer
| 3
|
[
"Prostate",
"cancer"
] |
[
3,
3
] |
NCT02309892
|
43:61:cancer
|
Histologically or cytologically confirmed non-squamous NSCLC
| 3
|
[
"Histologically",
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"cytologically",
"confirmed",
"non-squamous",
"NSCLC"
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[
0,
0,
0,
0,
3,
3
] |
NCT00969332
|
20:33:chronic_disease
|
Documented case of liver disease other than Parenteral Nutrition Associated Cholestasis
| 3
|
[
"Documented",
"case",
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"disease",
"other",
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"Nutrition",
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"Cholestasis"
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[
0,
0,
0,
2,
2,
0,
0,
0,
0,
0,
0
] |
NCT00914823
|
,12:46:chronic_disease
|
Women with Polycystic Ovarian Syndrome (PCOS)
| 3
|
[
"Women",
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"Polycystic",
"Ovarian",
"Syndrome",
"(",
"PCOS",
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] |
[
0,
0,
2,
2,
2,
2,
0,
0
] |
NCT02912572
|
,68:74:cancer,100:107:treatment,111:117:treatment
|
Availability of a formalin fixed paraffin embedded (FFPE) block of cancer tissue from the original surgery or biopsy or from a biopsy of recurrent disease
| 3
|
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NCT02389309
|
1:9:treatment,18:29:treatment,34:56:treatment,98:106:treatment,161:167:treatment,169:176:treatment,,,276:285:treatment
|
Antacids: use of H2 blockers and proton pump inhibitors is not recommended; patients who require antacids should use short acting, locally active agents (e.g., Maalox, Mylanta etc.); however, these agents should not be taken within either 2 hours before or 2 hours after the dasatinib dose
| 3
|
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NCT02266784
|
1:5:chronic_disease
|
ADHD Symptom Ratings
| 3
|
[
"ADHD",
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[
2,
0,
0
] |
NCT01697293
|
41:87:treatment
|
Patients may not be receiving any other investigational agents during protocol therapy
| 3
|
[
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NCT02547584
|
12:29:treatment,34:44:chronic_disease,48:61:chronic_disease
|
Undergoing catheter ablation for paroxysmal or persistent AF
| 3
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[
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0,
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1,
0,
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0,
2,
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NCT01943851
|
1:17:treatment
|
Topical steroids are permitted
| 3
|
[
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[
1,
1,
0,
0
] |
NCT03070145
|
1:22:chronic_disease,114:130:chronic_disease,134:143:chronic_disease,169:189:chronic_disease
|
Psychiatric disorders or conditions that would preclude participation in the study intervention (e.g., untreated major depression or psychosis, substance abuse, severe personality disorder)
| 3
|
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NCT01522768
|
30:39:treatment,43:53:treatment,57:75:treatment
|
Prior disease progression on docetaxel or paclitaxel in metastatic setting
| 3
|
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0,
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0,
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NCT02390752
|
34:60:treatment
|
There are no limits on number of prior therapeutic regimens
| 3
|
[
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0,
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0,
0,
0,
0,
1,
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NCT02043548
|
1:10:treatment,20:41:treatment,,,81:101:treatment
|
Treatment with any investigational agent within 4 weeks (or 5 half-lives of the investigational drug, whichever is longer) of screening
| 3
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NCT02509507
|
83:102:cancer,106:111:cancer,141:154:treatment
|
For the combination cohorts (Cohorts 5 and 6 in Part 1) and Part 2, subjects with metastatic melanoma or NSCLC do not need to have received prior therapy
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NCT02266745
|
1:16:treatment,,28:38:treatment,57:80:treatment,71:80:treatment,88:102:treatment,,142:152:treatment
|
corticosteroids >20 mg/day prednisone or equivalent, or growth factor treatment (e.g., erythropoietin) within 14 days prior to initiation of study drug
| 3
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NCT03099590
|
20:29:chronic_disease
|
Subject has active hepatitis
| 3
|
[
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[
0,
0,
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NCT02187198
|
8:14:treatment,
|
use of heroin for more than 4 days in the past month
| 3
|
[
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0,
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0,
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0,
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NCT01503086
|
,,,194:197:treatment
|
must have an identified caregiver who is willing and able to oversee the training practice during the intervention period (ie, for 5-9 weeks starting approximately 3 months after completion of CRT)
| 3
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NCT01430390
|
37:45:cancer,177:198:chronic_disease,220:242:chronic_disease,,262:271:treatment
|
Active central nervous system (CNS) leukemia, as defined by unequivocal morphologic evidence of lymphoblasts in the cerebrospinal fluid (CSF) or symptomatic CNS leukemia (i.e. cranial nerve palsies or other significant neurologic dysfunction) within 28 days of treatment
| 3
|
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NCT02836574
|
1:20:chronic_disease,59:73:chronic_disease,,108:121:treatment
|
acute kidney injury or has experienced a rapid decline in renal function during the last 3 months prior to NKA injection
| 3
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NCT01947140
|
1:14:treatment
|
Prior Therapy
| 3
|
[
"Prior",
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] |
[
1,
1
] |
NCT02910648
|
12:33:chronic_disease
|
History of major medical disease impacting study
| 3
|
[
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[
0,
0,
2,
2,
2,
0,
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NCT01670877
|
21:37:cancer,75:84:treatment,96:104:treatment,
|
Patients with known brain metastasis are eligible, but must have received radiation and be off steroids and stable (without evidence of disease progression by imaging or exam) for 3 months
| 3
|
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NCT01037790
|
15:19:cancer,35:41:cancer,54:65:treatment,93:100:treatment,158:167:treatment
|
Patients with HER2-overexpressing tumors may receive trastuzumab up to the date of starting therapy, and may continue to receive trastuzumab while receiving PD0332991
| 3
|
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NCT00734877
|
19:31:chronic_disease,33:50:chronic_disease,69:84:chronic_disease,88:107:chronic_disease,164:173:treatment
|
Poorly controlled hypertension, diabetes mellitus, or other serious medical illness or psychiatric illness that could potentially interfere with the completion of treatment according to this protocol
| 3
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NCT02908906
|
1:13:treatment
|
radiotherapy
| 3
|
[
"radiotherapy"
] |
[
1
] |
NCT02106650
|
26:33:treatment,
|
had previous exposure to Folotyn within 6 months of study enrollment
| 3
|
[
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NCT02203695
|
,,,,,283:293:treatment
|
male patient and his female partner who is of childbearing potential must use 2 acceptable methods of birth control (1 of which must include a condom as a barrier method of contraception) starting at screening and continuing throughout the study period and for 3 months after final study drug administration or per local guidelines where these require additional description of contraceptive methods
| 3
|
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NCT02680574
|
11:34:chronic_disease
|
sustained ventricular tachycardia
| 3
|
[
"sustained",
"ventricular",
"tachycardia"
] |
[
0,
2,
2
] |
NCT01940757
|
36:46:chronic_disease,48:55:chronic_disease,57:66:chronic_disease,68:75:chronic_disease,77:90:chronic_disease,92:102:chronic_disease,104:112:chronic_disease,117:130:chronic_disease
|
Evidence of clinically significant neurologic, cardiac, pulmonary, hepatic, rheumatologic, autoimmune, diabetes, or renal disease by history, physical examination, and/or laboratory studies
| 3
|
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NCT02589977
|
,,58:74:treatment
|
preserved left ventricular ejection fraction (>= 50%) on echocardiography
| 3
|
[
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NCT03092011
|
14:44:chronic_disease
|
Infants with major congenital abnormalities
| 3
|
[
"Infants",
"with",
"major",
"congenital",
"abnormalities"
] |
[
0,
0,
2,
2,
2
] |
NCT02131805
|
1:8:cancer
|
BCC/SCC that was previously treated (ie, recurrent BCC/SCC)
| 3
|
[
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"(",
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"BCC/SCC",
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[
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0,
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0,
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NCT02437812
|
34:49:treatment
|
Patients must be able to swallow oral medication
| 3
|
[
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"must",
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"to",
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"oral",
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] |
[
0,
0,
0,
0,
0,
0,
1,
1
] |
NCT01676259
|
1:14:treatment
|
major surgery
| 3
|
[
"major",
"surgery"
] |
[
1,
1
] |
NCT03007030
|
,,,,,,,250:269:treatment
|
willing to use an acceptable method of birth control (i.e., a hormonal contraceptive, intra-uterine device, diaphragm with spermicide, condom with spermicide, or abstinence) for the duration of the study and at least 6 months after the last dose of brentuximab vedotin
| 3
|
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NCT03036319
|
1:29:chronic_disease
|
Sensory or motor impairments that limit the ability to take part in the study
| 3
|
[
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NCT01822522
|
45:70:treatment,155:162:treatment,,,396:405:treatment
|
participants will be eligible regardless of antiretroviral medication (including no antiretroviral medication) provided there is no intention to initiate therapy or the regimen has been stable for at least 4 weeks with no intention to change the regimen within 8 weeks following study entry; as study-specific (antiretroviral-based) strata fill, however, only participants who are receiving the therapies eligible for the remaining open strata will be accrued
| 3
|
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"open",
"strata",
"will",
"be",
"accrued"
] |
[
0,
0,
0,
0,
0,
0,
1,
1,
0,
0,
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0,
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] |
NCT02923921
|
28:45:treatment,49:72:treatment,81:90:treatment,94:121:cancer
|
not have received previous radiation therapy or investigational therapy for the treatment of advanced metastatic disease
| 3
|
[
"not",
"have",
"received",
"previous",
"radiation",
"therapy",
"or",
"investigational",
"therapy",
"for",
"the",
"treatment",
"of",
"advanced",
"metastatic",
"disease"
] |
[
0,
0,
0,
0,
1,
1,
0,
1,
1,
0,
0,
1,
0,
3,
3,
3
] |
NCT03089905
|
41:52:treatment,
|
Previous cumulative exposure to general anaesthesia exceeding 2 hours
| 3
|
[
"Previous",
"cumulative",
"exposure",
"to",
"general",
"anaesthesia",
"exceeding",
"2",
"hours"
] |
[
0,
0,
0,
0,
0,
1,
0,
0,
0
] |
NCT01474889
|
1:25:chronic_disease,27:43:chronic_disease,48:62:chronic_disease
|
Untreated hypothyroidism, Addisons disease, or Celiac disease
| 3
|
[
"Untreated",
"hypothyroidism",
",",
"Addisons",
"disease",
",",
"or",
"Celiac",
"disease"
] |
[
2,
2,
0,
2,
2,
0,
0,
2,
2
] |
NCT02747238
|
13:22:treatment
|
Request for analgesia for labor pain
| 3
|
[
"Request",
"for",
"analgesia",
"for",
"labor",
"pain"
] |
[
0,
0,
1,
0,
0,
0
] |
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