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NCT02171104
|
1:19:chronic_disease
|
Alpha mannosidosis
| 3
|
[
"Alpha",
"mannosidosis"
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[
2,
2
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NCT02461927
|
9:34:chronic_disease,,,,
|
Current uncontrolled hypertension (systolic BP > 170 mm Hg or diastolic BP > 100 mm Hg)
| 3
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NCT03168776
|
44:75:treatment
|
Patients who are receiving or will require chronic anticoagulation therapy for any reason
| 3
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NCT02362308
|
51:61:treatment,209:218:chronic_disease,232:268:treatment
|
Any underlying or acute disease requiring regular medication which could possibly pose a threat to the subject or make implementation of the protocol or interpretation of the study results difficult, such as arthritis treated with non-steroidal antiinflammatory drugs
| 3
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NCT02225548
|
24:42:chronic_disease
|
Diagnosis of any other neurologic disease
| 3
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NCT02371720
|
30:41:treatment
|
Patient is on liquid form of Hydroxyurea since MPR
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NCT03110107
|
37:49:treatment,51:63:treatment,65:73:treatment,78:91:treatment,103:118:treatment
|
rior anti-cancer treatments such as chemotherapy, radiotherapy, hormonal, or immunotherapy (including anti-PD-1/PD-L1) are permitted
| 3
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NCT02543723
|
48:68:treatment
|
Current participation in a similar study or in investigational drug trials where adverse effects have not been fully elucidated
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NCT01993810
|
1:12:cancer,17:49:cancer,51:62:cancer,64:70:cancer
|
skin cancer and in situ carcinomas of the breast, oral cavity, cervix, and other organs and are permissible
| 3
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NCT02021604
|
26:42:chronic_disease,32:42:chronic_disease,71:81:cancer,273:280:treatment
|
Patients thought to have focal HI disease based on genetic testing or insulinoma based on clinical evaluation and have well-controlled blood glucose levels with any degree of dietary or medical management, BUT the patient and their parent(s) or LAR wishes to proceed with surgery for a possible cure of HI disease
| 3
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NCT01925378
|
15:24:allergy_name,34:45:allergy_name,49:59:allergy_name,96:105:treatment
|
Patients with allergies or known sensitivity to Nelfinavir will be excluded or withdrawn after treatment, if deemed a safety concern by the principal Investigator
| 3
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NCT03005418
|
25:47:treatment
|
HAV may not be used for coronary artery repair
| 3
|
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NCT02413047
|
1:29:cancer
|
non-melanomatous skin cancer
| 3
|
[
"non-melanomatous",
"skin",
"cancer"
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[
3,
3,
3
] |
NCT02857218
|
1:29:cancer
|
non-melanomatous skin cancer
| 3
|
[
"non-melanomatous",
"skin",
"cancer"
] |
[
3,
3,
3
] |
NCT01989585
|
1:12:treatment,14:28:treatment,30:43:treatment,45:59:treatment
|
Antibiotics: clarithromycin, telithromycin, troleandomycin
| 3
|
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NCT02519322
|
35:40:cancer,55:61:treatment,137:146:treatment
|
if a sample contains insufficient tumor content, a re-biopsy will be required to obtain a sample with sufficient tumor content prior to treatment
| 3
|
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NCT01703117
|
1:4:allergy_name,30:44:chronic_disease,46:60:allergy_name,62:68:allergy_name,70:79:allergy_name,81:95:allergy_name,97:109:allergy_name
|
MRI contraindication (severe claustrophobia, metal implants, shunts, pacemaker, joint implants, metal valves)
| 3
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NCT02446236
|
56:59:cancer
|
Histologically or cytologically confirmed diagnosis of MCL
| 3
|
[
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] |
[
0,
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NCT03059888
|
26:70:chronic_disease
|
Subject has a history of Chronic Obstructive Pulmonary Disease (COPD)
| 3
|
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NCT03034395
|
1:9:cancer
|
Melanoma located on face or digits
| 3
|
[
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"located",
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"digits"
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[
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NCT03090607
|
13:41:chronic_disease
|
Presence of esophageal motility disorder
| 3
|
[
"Presence",
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"motility",
"disorder"
] |
[
0,
0,
2,
2,
2
] |
NCT02266784
|
5:9:chronic_disease,,
|
For ADHD Groups: T-Score > 65 on one of the DSM-IV relevant scales
| 3
|
[
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NCT02474368
|
,,53:65:treatment
|
Pregnant women are excluded from this study because radiotherapy has the potential for teratogenic or abortifacient effects
| 3
|
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NCT02008136
|
4:30:treatment,
|
No botulinum toxin injections in the last 6 months
| 3
|
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NCT02863991
|
1:44:chronic_disease,55:72:chronic_disease,74:91:chronic_disease
|
Active bacterial, fungal or viral infection including hepatitis B (HBV), hepatitis C (HCV)
| 3
|
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NCT01614197
|
10:23:treatment,
|
Positive blood culture within 48 hours of study enrollment
| 3
|
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NCT02574910
|
24:33:chronic_disease
|
Presence or history of cataracts
| 3
|
[
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[
0,
0,
0,
0,
2
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NCT02128100
|
1:19:cancer
|
Metastatic disease as defined by the multi-disciplinary team
| 3
|
[
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3,
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0,
0,
0,
0,
0
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NCT02907918
|
47:115:allergy_name,117:126:allergy_name,128:139:allergy_name,151:170:allergy_name,182:201:allergy_name,206:236:allergy_name
|
A history of allergic reactions attributed to compounds of similar chemical or biologic composition to palbociclib, letrozole, trastuzumab, any other aromatase inhibitor, any other monoclonal antibody, or other agents used in the study
| 3
|
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NCT01871727
|
,6:11:treatment,21:26:cancer,,96:115:cancer,119:135:treatment,139:159:treatment
|
CD25 assay-positive tumor, defined as detectable CD25 on greater than or equal to 20% of total lymphoid infiltrate in biopsied lesions by immunohistochemistry
| 3
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NCT02245997
|
35:48:cancer
|
Patients must have a diagnosis of neuroblastoma (International Classification of Disease for Oncology [ICD-O] morphology 9500/3) confirmed by MSKCC pathologic review
| 3
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NCT00573027
|
1:24:chronic_disease
|
Acute coronary syndrome (defined by the ACC/AHA criteria, Braunwald 2000)
| 3
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NCT02793921
|
9:21:treatment
|
Current beta-blocker use
| 3
|
[
"Current",
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[
0,
1,
0
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NCT02588326
|
1:10:chronic_disease
|
emphysema
| 3
|
[
"emphysema"
] |
[
2
] |
NCT00948285
|
,58:61:treatment
|
Patients who weigh more than 350 pounds (weight limit on MRI machine)
| 3
|
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NCT01989585
|
20:30:cancer,,107:112:cancer,183:200:cancer,332:340:cancer,344:358:cancer,362:378:treatment,462:486:cancer,517:539:cancer,606:625:cancer,723:729:cancer
|
History of another malignancy; exception: patients who have been disease-free for 3 years (depending upon tumor type studied or clinical setting, 3 or 5 years can be used; e.g., for advanced melanoma and pancreatic studies 3 years is more appropriate due to aggressiveness of the disease, while 5 years can be more appropriate for prostate or ovarian cancer or adjuvant setting when life expectancy is longer), or patients with a history of completely resected non-melanoma skin cancer and/or patients with indolent secondary malignancies, are eligible; consult the CTEP medical monitor if unsure whether second malignancies meet the requirements specified above; exception: patients with history of RAS mutation-positive tumors are not eligible regardless of interval from the current study; prospective RAS testing is not required; however, if the results of previous RAS testing are known, they must be used in assessing eligibility
| 3
|
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NCT02932956
|
,124:139:treatment
|
Sexually active patients must be willing to utilize one of the more effective birth control methods for 3 months after the T-cell infusion
| 3
|
[
"Sexually",
"active",
"patients",
"must",
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NCT02216227
|
12:34:treatment
|
Undergoing hip and knee revisions
| 3
|
[
"Undergoing",
"hip",
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"knee",
"revisions"
] |
[
0,
1,
1,
1,
1
] |
NCT02120222
|
1:24:chronic_disease
|
Unstable cardiovascular
| 3
|
[
"Unstable",
"cardiovascular"
] |
[
2,
2
] |
NCT01871727
|
1:14:treatment,
|
Major surgery within 2 weeks of study enrollment
| 3
|
[
"Major",
"surgery",
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"weeks",
"of",
"study",
"enrollment"
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[
1,
1,
0,
0,
0,
0,
0,
0
] |
NCT02448173
|
15:38:treatment,42:54:treatment,66:76:cancer
|
Patients with prior radiation therapy or chemotherapy or a prior malignancy of any type will be excluded
| 3
|
[
"Patients",
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"therapy",
"or",
"chemotherapy",
"or",
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"prior",
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"of",
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"will",
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NCT02314377
|
24:48:treatment,50:61:treatment,,123:130:treatment
|
Patients must not have major surgical procedure, open biopsy, or significant traumatic injury within 4 weeks of beginning Avastin or the anticipation of need for major surgical procedure during the course of the study
| 3
|
[
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NCT02367040
|
125:134:treatment,125:153:treatment,146:153:treatment,155:185:treatment,218:234:treatment,292:312:treatment,385:407:treatment,443:459:treatment,461:482:treatment,484:502:treatment,525:529:treatment,555:565:treatment,635:650:treatment
|
Patients must have relapsed (recurrence after complete response or presented progression after partial response) after last rituximab-containing therapy (other previous treatment lines after rituximab are allowed). A previous regimen is defined as one of the following: at least 2 months of single-agent therapy (less than 2 months of therapy is allowed for patients who responded to single-agent rituximab); at least 2 consecutive cycles of polychemotherapy; autologous transplant; radioimmunotherapy. Previous exposure to PI3K is acceptable (except to copanlisib) provided there is no resistance. Patients with prior intolerance to PI3K inhibitors other than copanlisib are eligible
| 3
|
[
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NCT02584647
|
17:33:treatment
|
Any patients on warfarin therapy
| 3
|
[
"Any",
"patients",
"on",
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"therapy"
] |
[
0,
0,
0,
1,
1
] |
NCT02132598
|
4:8:cancer,12:28:cancer,,71:80:treatment
|
To bone or brain metastasis within 14 days of the first dose of study treatment
| 3
|
[
"To",
"bone",
"or",
"brain",
"metastasis",
"within",
"14",
"days",
"of",
"the",
"first",
"dose",
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0,
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3,
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0,
0,
0,
0,
0,
0,
0,
0,
0,
1
] |
NCT02059239
|
1:20:chronic_disease
|
Progressive disease
| 3
|
[
"Progressive",
"disease"
] |
[
2,
2
] |
NCT03170856
|
15:25:chronic_disease,
|
Experienced a concussion within the last 2 weeks
| 3
|
[
"Experienced",
"a",
"concussion",
"within",
"the",
"last",
"2",
"weeks"
] |
[
0,
0,
2,
0,
0,
0,
0,
0
] |
NCT02898701
|
120:129:chronic_disease
|
any other conditions that affect their mobility or balance which might affect their ability to perform the motor task (arthritis, orthopedic complications, metabolic, vestibular, etc)
| 3
|
[
"any",
"other",
"conditions",
"that",
"affect",
"their",
"mobility",
"or",
"balance",
"which",
"might",
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"their",
"ability",
"to",
"perform",
"the",
"motor",
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"(",
"arthritis",
",",
"orthopedic",
"complications",
",",
"metabolic",
",",
"vestibular",
",",
"etc",
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0,
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NCT01522768
|
28:43:treatment
|
Able to swallow and retain oral medication
| 3
|
[
"Able",
"to",
"swallow",
"and",
"retain",
"oral",
"medication"
] |
[
0,
0,
0,
0,
0,
1,
1
] |
NCT00293475
|
24:36:treatment
|
eligible for full dose methotrexate
| 3
|
[
"eligible",
"for",
"full",
"dose",
"methotrexate"
] |
[
0,
0,
0,
0,
1
] |
NCT03023319
|
17:27:treatment,29:40:treatment,46:59:treatment
|
Ability to take folic acid, vitamin B12, and dexamethasone according to protocol
| 3
|
[
"Ability",
"to",
"take",
"folic",
"acid",
",",
"vitamin",
"B12",
",",
"and",
"dexamethasone",
"according",
"to",
"protocol"
] |
[
0,
0,
0,
1,
1,
0,
1,
1,
0,
0,
1,
0,
0,
0
] |
NCT02336451
|
17:38:treatment,69:76:treatment,78:103:treatment,105:126:treatment,128:152:treatment,204:214:treatment
|
Planning of any brain local treatment (including but not limited to surgery, stereotactic radiosurgery, whole brain radiation, intrathecal chemotherapy) following the administration of the first dose of study drug
| 3
|
[
"Planning",
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"any",
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"local",
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"(",
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"but",
"not",
"limited",
"to",
"surgery",
",",
"stereotactic",
"radiosurgery",
",",
"whole",
"brain",
"radiation",
",",
"intrathecal",
"chemotherapy",
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"following",
"the",
"administration",
"of",
"the",
"first",
"dose",
"of",
"study",
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] |
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0,
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0,
0,
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0,
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0,
1,
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] |
NCT02439450
|
7:33:chronic_disease
|
Known immunodeficiency disorders, either primary or acquired
| 3
|
[
"Known",
"immunodeficiency",
"disorders",
",",
"either",
"primary",
"or",
"acquired"
] |
[
0,
2,
2,
0,
0,
0,
0,
0
] |
NCT02978443
|
25:41:cancer,43:65:cancer,70:87:chronic_disease
|
Patients with untreated brain metastases, leptomeningeal disease, or seizure disorders
| 3
|
[
"Patients",
"with",
"untreated",
"brain",
"metastases",
",",
"leptomeningeal",
"disease",
",",
"or",
"seizure",
"disorders"
] |
[
0,
0,
0,
3,
3,
0,
3,
3,
0,
0,
2,
2
] |
NCT02481310
|
1:17:cancer
|
Burkitt lymphoma
| 3
|
[
"Burkitt",
"lymphoma"
] |
[
3,
3
] |
NCT02236000
|
12:33:treatment,
|
Use of any investigational agent within 4 weeks prior to study entry
| 3
|
[
"Use",
"of",
"any",
"investigational",
"agent",
"within",
"4",
"weeks",
"prior",
"to",
"study",
"entry"
] |
[
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0
] |
NCT02823665
|
31:48:treatment
|
Asymptomatic individuals with bariatric surgery
| 3
|
[
"Asymptomatic",
"individuals",
"with",
"bariatric",
"surgery"
] |
[
0,
0,
0,
1,
1
] |
NCT02585973
|
1:23:cancer,25:31:cancer,33:44:cancer
|
T4 disease Oral Cavity, Larynx, Hypopharynx are considered high/intermediate risk (regardless of HPV, p16 or smoking status)
| 3
|
[
"T4",
"disease",
"Oral",
"Cavity",
",",
"Larynx",
",",
"Hypopharynx",
"are",
"considered",
"high/intermediate",
"risk",
"(",
"regardless",
"of",
"HPV",
",",
"p16",
"or",
"smoking",
"status",
")"
] |
[
3,
3,
3,
3,
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3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT02169037
|
1:25:chronic_disease
|
Congestive heart failure (1 point)
| 3
|
[
"Congestive",
"heart",
"failure",
"(",
"1",
"point",
")"
] |
[
2,
2,
2,
0,
0,
0,
0
] |
NCT02456857
|
81:120:chronic_disease,158:173:chronic_disease,177:235:chronic_disease,237:250:chronic_disease,259:268:chronic_disease,270:297:chronic_disease,303:331:chronic_disease,351:374:chronic_disease,442:467:chronic_disease,482:505:chronic_disease,540:571:chronic_disease,,,,,741:759:chronic_disease,764:801:chronic_disease
|
Patients who have any severe and/or uncontrolled medical conditions such as: a. serious uncontrolled cardiac arrhythmia, or any other clinically significant cardiac disease b. active (acute or chronic) or uncontrolled severe infection, liver disease such as cirrhosis, decompensated liver disease, and active and chronic hepatitis (i.e. quantifiable hepatitis B virus [HBV]-deoxyribonucleic acid [DNA] and/or positive surface antigen of the hepatitis B virus [HBsAg], quantifiable hepatitis C virus [HCV]-ribonucleic acid [RNA]), c. known severely impaired lung function (spirometry and Diffusing capacity of the lungs for carbon monoxide [DLCO] 50% or less of normal and oxygen (O2) saturation 88% or less at rest on room air), d. active, bleeding diathesis; e. Moderate or severe hepatic impairment (Child-Pugh B or C)
| 3
|
[
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NCT02389309
|
61:83:chronic_disease,94:106:treatment,117:136:treatment,138:157:chronic_disease
|
Uncontrolled current illness including, but not limited to, uncontrolled infection, need for hemodialysis, need for ventilatory support, psychiatric illness/social situations that would limit compliance with study requirements
| 3
|
[
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",",
"need",
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"hemodialysis",
",",
"need",
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"support",
",",
"psychiatric",
"illness/social",
"situations",
"that",
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"compliance",
"with",
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0,
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0,
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NCT01895777
|
31:51:treatment,
|
Patients who have received an investigational drug in the past 30 days prior to screening
| 3
|
[
"Patients",
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NCT02276716
|
17:22:treatment,24:30:treatment,34:55:treatment
|
Patients taking ginko, garlic or vitamin E supplements
| 3
|
[
"Patients",
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"ginko",
",",
"garlic",
"or",
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"E",
"supplements"
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[
0,
0,
1,
0,
1,
0,
1,
1,
1
] |
NCT00630565
|
41:69:chronic_disease,130:134:treatment,141:170:treatment
|
The patient must be free of symptoms of uncontrolled cardiac disease, and must not have compromised cardiac function detected by ECHO or by gated cardiac blood flow scan
| 3
|
[
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1,
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1,
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] |
NCT03085485
|
1:19:treatment
|
herbal medications
| 3
|
[
"herbal",
"medications"
] |
[
1,
1
] |
NCT02021279
|
16:22:chronic_disease,26:52:chronic_disease,67:88:chronic_disease,90:119:chronic_disease,124:139:chronic_disease
|
Subject has an active or chronic systemic infection including any gynecologic infection, urinary tract infection (UTI), or tissue necrosis
| 3
|
[
"Subject",
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NCT02960555
|
1:14:treatment,
|
Major surgery within 1 month prior to enrollment
| 3
|
[
"Major",
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"month",
"prior",
"to",
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] |
[
1,
1,
0,
0,
0,
0,
0,
0
] |
NCT03037983
|
1:13:treatment
|
clomipramine
| 3
|
[
"clomipramine"
] |
[
1
] |
NCT01421810
|
34:48:chronic_disease,
|
Subjects with adequately treated hypothyroidism, reflected by normal TSH values
| 3
|
[
"Subjects",
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"adequately",
"treated",
"hypothyroidism",
",",
"reflected",
"by",
"normal",
"TSH",
"values"
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[
0,
0,
0,
0,
2,
0,
0,
0,
0,
0,
0
] |
NCT01903330
|
1:12:chronic_disease,16:27:chronic_disease,41:53:chronic_disease
|
Hepatitis B or Hepatitis C Uncontrolled hypertension
| 3
|
[
"Hepatitis",
"B",
"or",
"Hepatitis",
"C",
"Uncontrolled",
"hypertension"
] |
[
2,
2,
0,
0,
0,
0,
2
] |
NCT00919503
|
20:40:chronic_disease
|
DONOR: With active infectious hepatitis
| 3
|
[
"DONOR",
":",
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"hepatitis"
] |
[
0,
0,
0,
0,
2,
2
] |
NCT00467987
|
1:15:chronic_disease,19:28:treatment,30:51:chronic_disease,53:68:chronic_disease,70:92:treatment,94:101:treatment,105:125:treatment,,,
|
Coronary event or procedure (myocardial infarction, unstable angina, coronary artery bypass, surgery or coronary angioplasty) in the previous four weeks; 2)Hemoglobin A1c >10%
| 3
|
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NCT00147056
|
1:32:treatment
|
Anti-arrhythmic drug medication
| 3
|
[
"Anti-arrhythmic",
"drug",
"medication"
] |
[
1,
1,
1
] |
NCT03007030
|
1:23:treatment,
|
whole pelvic radiation is considered to be over 25%
| 3
|
[
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0,
0,
0,
0,
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0
] |
NCT02993406
|
34:62:chronic_disease,73:96:chronic_disease,98:137:chronic_disease,139:178:chronic_disease
|
History of, or at high risk for, cardiovascular disease (CVD) including coronary artery disease, symptomatic peripheral arterial disease, cerebrovascular atherosclerotic disease
| 3
|
[
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NCT02539160
|
4:13:treatment,28:35:treatment,51:62:treatment
|
On treatment with low-dose aspirin (81mg/day) and clopidogrel (75mg/day)
| 3
|
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NCT02516813
|
35:48:chronic_disease,66:90:chronic_disease,157:160:treatment,169:216:treatment
|
History of difficulty swallowing, malabsorption or other chronic gastrointestinal disease or conditions that may hamper compliance and/or absorption of the IMP, use of percutaneous endoscopic gastrostomy (PEG) tubes
| 3
|
[
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NCT02462590
|
11:42:treatment
|
receiving invasive mechanical ventilation
| 3
|
[
"receiving",
"invasive",
"mechanical",
"ventilation"
] |
[
0,
1,
1,
1
] |
NCT02844907
|
1:24:chronic_disease
|
Coronary artery disease
| 3
|
[
"Coronary",
"artery",
"disease"
] |
[
2,
2,
2
] |
NCT02108860
|
59:78:chronic_disease
|
Current clinical, radiographic, or laboratory evidence of active tuberculosis
| 3
|
[
"Current",
"clinical",
",",
"radiographic",
",",
"or",
"laboratory",
"evidence",
"of",
"active",
"tuberculosis"
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[
0,
0,
0,
0,
0,
0,
0,
0,
0,
2,
2
] |
NCT02557321
|
27:37:treatment,
|
the subject is not taking prednisone at >10 mg or equivalent daily
| 3
|
[
"the",
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0,
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0,
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0,
0,
0,
0,
0,
0,
0
] |
NCT02307565
|
1:14:treatment,
|
Major surgery in the last 30 days
| 3
|
[
"Major",
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"last",
"30",
"days"
] |
[
1,
1,
0,
0,
0,
0,
0
] |
NCT02819635
|
1:26:chronic_disease,,,
|
Active ulcerative colitis with an Adapted Mayo score of 5 to 9 points
| 3
|
[
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"colitis",
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"Adapted",
"Mayo",
"score",
"of",
"5",
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[
2,
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2,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT03078907
|
15:39:treatment,81:96:treatment,100:114:treatment
|
Patients on a PAH-specific monotherapy targeting the nitric oxide pathway (i.e. PDE-5 inhibitor or sGC stimulator)
| 3
|
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NCT02385110
|
,,,,,251:261:treatment
|
Male patients with female partners who are of childbearing potential: Recommendation is for male and partner to use at least 2 effective contraceptive methods, as described above, prior to study entry and for at least 3 months after the last dose of study drug
| 3
|
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NCT03122912
|
12:37:chronic_disease,39:65:chronic_disease,67:93:chronic_disease,96:106:chronic_disease
|
History of photosensitive conditions (connective tissue diseases, polymorphous light eruption, porphyrias etc)
| 3
|
[
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NCT00967785
|
,,,,137:147:treatment
|
Willingness to interrupt medications to raise the white count (WBC) such as G-CSF or GM-CSF for at least 1 week before and while on the study drug
| 3
|
[
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] |
NCT02343549
|
13:31:chronic_disease,35:47:chronic_disease,67:94:treatment
|
Evidence of bleeding diathesis or coagulopathy (in the absence of therapeutic anticoagulation)
| 3
|
[
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0,
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1,
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] |
NCT02520778
|
24:49:treatment
|
prior treatment with a third-generation EGFR TKI is allowed for the dose escalation phase, but is not permitted for the expansion cohort
| 3
|
[
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NCT03035474
|
1:17:chronic_disease,29:31:chronic_disease,41:51:cancer,,
|
Terminal illness other than HF, such as malignancy, or with a life expectancy of less than 1 year as determined by the enrolling clinician-investigator
| 3
|
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NCT03171480
|
1:23:treatment,67:73:chronic_disease,82:93:chronic_disease,95:116:chronic_disease,127:139:chronic_disease
|
Isosorbide mononitrate should not be used in patients with severe anemia, severe hypotension, closed angle glaucoma or severe hypovolaemia
| 3
|
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NCT01174121
|
8:27:chronic_disease,38:62:treatment,64:85:chronic_disease,130:147:chronic_disease
|
Active systemic infections requiring anti-infective treatment, coagulation disorders, or any other active or uncompensated major medical illnesses
| 3
|
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] |
NCT01807117
|
17:19:cancer,25:31:cancer,178:195:cancer,214:227:cancer,249:266:cancer
|
Either having a T3 (the cancer has grown through the muscularis propria and into the outermost layers of the colon or rectum but not through them) or higher, node positivity or metastatic lesion in the context of rectal cancer or being studied for colorectal cancer follow up, independent of the renal function
| 3
|
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NCT02453373
|
1:20:chronic_disease
|
Sickle cell disease
| 3
|
[
"Sickle",
"cell",
"disease"
] |
[
2,
2,
2
] |
NCT02510456
|
10:20:cancer,33:43:cancer,47:82:cancer,86:103:cancer,
|
Previous malignancy, other than basal cell or squamous cell carcinoma of the skin or in situ carcinoma of the cervix, from which the patient has been disease free for less than 5 years
| 3
|
[
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"disease",
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"for",
"less",
"than",
"5",
"years"
] |
[
0,
3,
0,
0,
0,
3,
3,
0,
3,
3,
3,
3,
3,
3,
0,
3,
3,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT01532687
|
,37:47:treatment
|
for 6 months prior to first dose of study drug
| 3
|
[
"for",
"6",
"months",
"prior",
"to",
"first",
"dose",
"of",
"study",
"drug"
] |
[
0,
0,
0,
0,
0,
0,
0,
0,
1,
1
] |
NCT02427841
|
5:18:treatment,20:32:treatment,34:43:treatment,47:54:treatment,60:85:cancer,97:118:treatment
|
Any prior therapy (chemotherapy, radiation or surgery) for pancreatic adenocarcinoma other than biliary decompression
| 3
|
[
"Any",
"prior",
"therapy",
"(",
"chemotherapy",
",",
"radiation",
"or",
"surgery",
")",
"for",
"pancreatic",
"adenocarcinoma",
"other",
"than",
"biliary",
"decompression"
] |
[
0,
1,
1,
0,
1,
0,
1,
0,
1,
0,
0,
3,
3,
0,
0,
1,
1
] |
NCT02465268
|
,,,,176:186:treatment
|
Women of childbearing potential and male participants must be willing to practice adequate contraception throughout the study and for at least 24 weeks after the last dose of study drug
| 3
|
[
"Women",
"of",
"childbearing",
"potential",
"and",
"male",
"participants",
"must",
"be",
"willing",
"to",
"practice",
"adequate",
"contraception",
"throughout",
"the",
"study",
"and",
"for",
"at",
"least",
"24",
"weeks",
"after",
"the",
"last",
"dose",
"of",
"study",
"drug"
] |
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT02169739
|
39:41:chronic_disease,45:56:chronic_disease,58:85:chronic_disease
|
High risk of bleeding (e.g. recurrent GI or GU bleeding, active peptic ulcer disease, etc.)
| 3
|
[
"High",
"risk",
"of",
"bleeding",
"(",
"e.g",
".",
"recurrent",
"GI",
"or",
"GU",
"bleeding",
",",
"active",
"peptic",
"ulcer",
"disease",
",",
"etc",
".",
")"
] |
[
0,
0,
0,
0,
0,
0,
0,
0,
2,
0,
2,
2,
0,
2,
2,
2,
2,
0,
0,
0,
0
] |
NCT03004287
|
,81:100:treatment,107:134:treatment,136:175:treatment,177:198:treatment,203:222:treatment
|
Patients must be either untreated or have not received more than four cycles of systemic MM therapy (e.g. Revlimid Dexamethasone (RD), Bortezomib Revlimid Dexamethasone (VRD). Prior bisphosphonates and localized radiation are allowed
| 3
|
[
"Patients",
"must",
"be",
"either",
"untreated",
"or",
"have",
"not",
"received",
"more",
"than",
"four",
"cycles",
"of",
"systemic",
"MM",
"therapy",
"(",
"e.g",
".",
"Revlimid",
"Dexamethasone",
"(",
"RD",
")",
",",
"Bortezomib",
"Revlimid",
"Dexamethasone",
"(",
"VRD",
")",
".",
"Prior",
"bisphosphonates",
"and",
"localized",
"radiation",
"are",
"allowed"
] |
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
1,
1,
1,
0,
0,
0,
1,
1,
1,
1,
0,
0,
0,
1,
1,
0,
1,
1,
0,
0
] |
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