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NCT02171104
1:19:chronic_disease
Alpha mannosidosis
3
[ "Alpha", "mannosidosis" ]
[ 2, 2 ]
NCT02461927
9:34:chronic_disease,,,,
Current uncontrolled hypertension (systolic BP > 170 mm Hg or diastolic BP > 100 mm Hg)
3
[ "Current", "uncontrolled", "hypertension", "(", "systolic", "BP", ">", "170", "mm", "Hg", "or", "diastolic", "BP", ">", "100", "mm", "Hg", ")" ]
[ 0, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT03168776
44:75:treatment
Patients who are receiving or will require chronic anticoagulation therapy for any reason
3
[ "Patients", "who", "are", "receiving", "or", "will", "require", "chronic", "anticoagulation", "therapy", "for", "any", "reason" ]
[ 0, 0, 0, 0, 0, 0, 0, 1, 1, 1, 0, 0, 0 ]
NCT02362308
51:61:treatment,209:218:chronic_disease,232:268:treatment
Any underlying or acute disease requiring regular medication which could possibly pose a threat to the subject or make implementation of the protocol or interpretation of the study results difficult, such as arthritis treated with non-steroidal antiinflammatory drugs
3
[ "Any", "underlying", "or", "acute", "disease", "requiring", "regular", "medication", "which", "could", "possibly", "pose", "a", "threat", "to", "the", "subject", "or", "make", "implementation", "of", "the", "protocol", "or", "interpretation", "of", "the", "study", "results", "difficult", ",", "such", "as", "arthritis", "treated", "with", "non-steroidal", "antiinflammatory", "drugs" ]
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NCT02225548
24:42:chronic_disease
Diagnosis of any other neurologic disease
3
[ "Diagnosis", "of", "any", "other", "neurologic", "disease" ]
[ 0, 0, 0, 0, 2, 2 ]
NCT02371720
30:41:treatment
Patient is on liquid form of Hydroxyurea since MPR
3
[ "Patient", "is", "on", "liquid", "form", "of", "Hydroxyurea", "since", "MPR" ]
[ 0, 0, 0, 0, 0, 0, 1, 0, 0 ]
NCT03110107
37:49:treatment,51:63:treatment,65:73:treatment,78:91:treatment,103:118:treatment
rior anti-cancer treatments such as chemotherapy, radiotherapy, hormonal, or immunotherapy (including anti-PD-1/PD-L1) are permitted
3
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[ 0, 0, 0, 0, 0, 1, 0, 1, 0, 1, 0, 0, 1, 0, 0, 1, 0, 0, 0 ]
NCT02543723
48:68:treatment
Current participation in a similar study or in investigational drug trials where adverse effects have not been fully elucidated
3
[ "Current", "participation", "in", "a", "similar", "study", "or", "in", "investigational", "drug", "trials", "where", "adverse", "effects", "have", "not", "been", "fully", "elucidated" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT01993810
1:12:cancer,17:49:cancer,51:62:cancer,64:70:cancer
skin cancer and in situ carcinomas of the breast, oral cavity, cervix, and other organs and are permissible
3
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NCT02021604
26:42:chronic_disease,32:42:chronic_disease,71:81:cancer,273:280:treatment
Patients thought to have focal HI disease based on genetic testing or insulinoma based on clinical evaluation and have well-controlled blood glucose levels with any degree of dietary or medical management, BUT the patient and their parent(s) or LAR wishes to proceed with surgery for a possible cure of HI disease
3
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NCT01925378
15:24:allergy_name,34:45:allergy_name,49:59:allergy_name,96:105:treatment
Patients with allergies or known sensitivity to Nelfinavir will be excluded or withdrawn after treatment, if deemed a safety concern by the principal Investigator
3
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NCT03005418
25:47:treatment
HAV may not be used for coronary artery repair
3
[ "HAV", "may", "not", "be", "used", "for", "coronary", "artery", "repair" ]
[ 0, 0, 0, 0, 0, 0, 1, 1, 1 ]
NCT02413047
1:29:cancer
non-melanomatous skin cancer
3
[ "non-melanomatous", "skin", "cancer" ]
[ 3, 3, 3 ]
NCT02857218
1:29:cancer
non-melanomatous skin cancer
3
[ "non-melanomatous", "skin", "cancer" ]
[ 3, 3, 3 ]
NCT01989585
1:12:treatment,14:28:treatment,30:43:treatment,45:59:treatment
Antibiotics: clarithromycin, telithromycin, troleandomycin
3
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[ 1, 0, 1, 0, 1, 0, 1 ]
NCT02519322
35:40:cancer,55:61:treatment,137:146:treatment
if a sample contains insufficient tumor content, a re-biopsy will be required to obtain a sample with sufficient tumor content prior to treatment
3
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NCT01703117
1:4:allergy_name,30:44:chronic_disease,46:60:allergy_name,62:68:allergy_name,70:79:allergy_name,81:95:allergy_name,97:109:allergy_name
MRI contraindication (severe claustrophobia, metal implants, shunts, pacemaker, joint implants, metal valves)
3
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NCT02446236
56:59:cancer
Histologically or cytologically confirmed diagnosis of MCL
3
[ "Histologically", "or", "cytologically", "confirmed", "diagnosis", "of", "MCL" ]
[ 0, 0, 0, 0, 0, 0, 3 ]
NCT03059888
26:70:chronic_disease
Subject has a history of Chronic Obstructive Pulmonary Disease (COPD)
3
[ "Subject", "has", "a", "history", "of", "Chronic", "Obstructive", "Pulmonary", "Disease", "(", "COPD", ")" ]
[ 0, 0, 0, 0, 0, 2, 2, 2, 2, 2, 0, 0 ]
NCT03034395
1:9:cancer
Melanoma located on face or digits
3
[ "Melanoma", "located", "on", "face", "or", "digits" ]
[ 3, 0, 0, 0, 0, 0 ]
NCT03090607
13:41:chronic_disease
Presence of esophageal motility disorder
3
[ "Presence", "of", "esophageal", "motility", "disorder" ]
[ 0, 0, 2, 2, 2 ]
NCT02266784
5:9:chronic_disease,,
For ADHD Groups: T-Score > 65 on one of the DSM-IV relevant scales
3
[ "For", "ADHD", "Groups", ":", "T-Score", ">", "65", "on", "one", "of", "the", "DSM-IV", "relevant", "scales" ]
[ 0, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02474368
,,53:65:treatment
Pregnant women are excluded from this study because radiotherapy has the potential for teratogenic or abortifacient effects
3
[ "Pregnant", "women", "are", "excluded", "from", "this", "study", "because", "radiotherapy", "has", "the", "potential", "for", "teratogenic", "or", "abortifacient", "effects" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02008136
4:30:treatment,
No botulinum toxin injections in the last 6 months
3
[ "No", "botulinum", "toxin", "injections", "in", "the", "last", "6", "months" ]
[ 0, 1, 1, 1, 0, 0, 0, 0, 0 ]
NCT02863991
1:44:chronic_disease,55:72:chronic_disease,74:91:chronic_disease
Active bacterial, fungal or viral infection including hepatitis B (HBV), hepatitis C (HCV)
3
[ "Active", "bacterial", ",", "fungal", "or", "viral", "infection", "including", "hepatitis", "B", "(", "HBV", ")", ",", "hepatitis", "C", "(", "HCV", ")" ]
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NCT01614197
10:23:treatment,
Positive blood culture within 48 hours of study enrollment
3
[ "Positive", "blood", "culture", "within", "48", "hours", "of", "study", "enrollment" ]
[ 0, 1, 1, 0, 0, 0, 0, 0, 0 ]
NCT02574910
24:33:chronic_disease
Presence or history of cataracts
3
[ "Presence", "or", "history", "of", "cataracts" ]
[ 0, 0, 0, 0, 2 ]
NCT02128100
1:19:cancer
Metastatic disease as defined by the multi-disciplinary team
3
[ "Metastatic", "disease", "as", "defined", "by", "the", "multi-disciplinary", "team" ]
[ 3, 3, 0, 0, 0, 0, 0, 0 ]
NCT02907918
47:115:allergy_name,117:126:allergy_name,128:139:allergy_name,151:170:allergy_name,182:201:allergy_name,206:236:allergy_name
A history of allergic reactions attributed to compounds of similar chemical or biologic composition to palbociclib, letrozole, trastuzumab, any other aromatase inhibitor, any other monoclonal antibody, or other agents used in the study
3
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NCT01871727
,6:11:treatment,21:26:cancer,,96:115:cancer,119:135:treatment,139:159:treatment
CD25 assay-positive tumor, defined as detectable CD25 on greater than or equal to 20% of total lymphoid infiltrate in biopsied lesions by immunohistochemistry
3
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NCT02245997
35:48:cancer
Patients must have a diagnosis of neuroblastoma (International Classification of Disease for Oncology [ICD-O] morphology 9500/3) confirmed by MSKCC pathologic review
3
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NCT00573027
1:24:chronic_disease
Acute coronary syndrome (defined by the ACC/AHA criteria, Braunwald 2000)
3
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NCT02793921
9:21:treatment
Current beta-blocker use
3
[ "Current", "beta-blocker", "use" ]
[ 0, 1, 0 ]
NCT02588326
1:10:chronic_disease
emphysema
3
[ "emphysema" ]
[ 2 ]
NCT00948285
,58:61:treatment
Patients who weigh more than 350 pounds (weight limit on MRI machine)
3
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NCT01989585
20:30:cancer,,107:112:cancer,183:200:cancer,332:340:cancer,344:358:cancer,362:378:treatment,462:486:cancer,517:539:cancer,606:625:cancer,723:729:cancer
History of another malignancy; exception: patients who have been disease-free for 3 years (depending upon tumor type studied or clinical setting, 3 or 5 years can be used; e.g., for advanced melanoma and pancreatic studies 3 years is more appropriate due to aggressiveness of the disease, while 5 years can be more appropriate for prostate or ovarian cancer or adjuvant setting when life expectancy is longer), or patients with a history of completely resected non-melanoma skin cancer and/or patients with indolent secondary malignancies, are eligible; consult the CTEP medical monitor if unsure whether second malignancies meet the requirements specified above; exception: patients with history of RAS mutation-positive tumors are not eligible regardless of interval from the current study; prospective RAS testing is not required; however, if the results of previous RAS testing are known, they must be used in assessing eligibility
3
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NCT02932956
,124:139:treatment
Sexually active patients must be willing to utilize one of the more effective birth control methods for 3 months after the T-cell infusion
3
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NCT02216227
12:34:treatment
Undergoing hip and knee revisions
3
[ "Undergoing", "hip", "and", "knee", "revisions" ]
[ 0, 1, 1, 1, 1 ]
NCT02120222
1:24:chronic_disease
Unstable cardiovascular
3
[ "Unstable", "cardiovascular" ]
[ 2, 2 ]
NCT01871727
1:14:treatment,
Major surgery within 2 weeks of study enrollment
3
[ "Major", "surgery", "within", "2", "weeks", "of", "study", "enrollment" ]
[ 1, 1, 0, 0, 0, 0, 0, 0 ]
NCT02448173
15:38:treatment,42:54:treatment,66:76:cancer
Patients with prior radiation therapy or chemotherapy or a prior malignancy of any type will be excluded
3
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NCT02314377
24:48:treatment,50:61:treatment,,123:130:treatment
Patients must not have major surgical procedure, open biopsy, or significant traumatic injury within 4 weeks of beginning Avastin or the anticipation of need for major surgical procedure during the course of the study
3
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NCT02367040
125:134:treatment,125:153:treatment,146:153:treatment,155:185:treatment,218:234:treatment,292:312:treatment,385:407:treatment,443:459:treatment,461:482:treatment,484:502:treatment,525:529:treatment,555:565:treatment,635:650:treatment
Patients must have relapsed (recurrence after complete response or presented progression after partial response) after last rituximab-containing therapy (other previous treatment lines after rituximab are allowed). A previous regimen is defined as one of the following: at least 2 months of single-agent therapy (less than 2 months of therapy is allowed for patients who responded to single-agent rituximab); at least 2 consecutive cycles of polychemotherapy; autologous transplant; radioimmunotherapy. Previous exposure to PI3K is acceptable (except to copanlisib) provided there is no resistance. Patients with prior intolerance to PI3K inhibitors other than copanlisib are eligible
3
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NCT02584647
17:33:treatment
Any patients on warfarin therapy
3
[ "Any", "patients", "on", "warfarin", "therapy" ]
[ 0, 0, 0, 1, 1 ]
NCT02132598
4:8:cancer,12:28:cancer,,71:80:treatment
To bone or brain metastasis within 14 days of the first dose of study treatment
3
[ "To", "bone", "or", "brain", "metastasis", "within", "14", "days", "of", "the", "first", "dose", "of", "study", "treatment" ]
[ 0, 3, 0, 3, 3, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1 ]
NCT02059239
1:20:chronic_disease
Progressive disease
3
[ "Progressive", "disease" ]
[ 2, 2 ]
NCT03170856
15:25:chronic_disease,
Experienced a concussion within the last 2 weeks
3
[ "Experienced", "a", "concussion", "within", "the", "last", "2", "weeks" ]
[ 0, 0, 2, 0, 0, 0, 0, 0 ]
NCT02898701
120:129:chronic_disease
any other conditions that affect their mobility or balance which might affect their ability to perform the motor task (arthritis, orthopedic complications, metabolic, vestibular, etc)
3
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NCT01522768
28:43:treatment
Able to swallow and retain oral medication
3
[ "Able", "to", "swallow", "and", "retain", "oral", "medication" ]
[ 0, 0, 0, 0, 0, 1, 1 ]
NCT00293475
24:36:treatment
eligible for full dose methotrexate
3
[ "eligible", "for", "full", "dose", "methotrexate" ]
[ 0, 0, 0, 0, 1 ]
NCT03023319
17:27:treatment,29:40:treatment,46:59:treatment
Ability to take folic acid, vitamin B12, and dexamethasone according to protocol
3
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NCT02336451
17:38:treatment,69:76:treatment,78:103:treatment,105:126:treatment,128:152:treatment,204:214:treatment
Planning of any brain local treatment (including but not limited to surgery, stereotactic radiosurgery, whole brain radiation, intrathecal chemotherapy) following the administration of the first dose of study drug
3
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NCT02439450
7:33:chronic_disease
Known immunodeficiency disorders, either primary or acquired
3
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[ 0, 2, 2, 0, 0, 0, 0, 0 ]
NCT02978443
25:41:cancer,43:65:cancer,70:87:chronic_disease
Patients with untreated brain metastases, leptomeningeal disease, or seizure disorders
3
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NCT02481310
1:17:cancer
Burkitt lymphoma
3
[ "Burkitt", "lymphoma" ]
[ 3, 3 ]
NCT02236000
12:33:treatment,
Use of any investigational agent within 4 weeks prior to study entry
3
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NCT02823665
31:48:treatment
Asymptomatic individuals with bariatric surgery
3
[ "Asymptomatic", "individuals", "with", "bariatric", "surgery" ]
[ 0, 0, 0, 1, 1 ]
NCT02585973
1:23:cancer,25:31:cancer,33:44:cancer
T4 disease Oral Cavity, Larynx, Hypopharynx are considered high/intermediate risk (regardless of HPV, p16 or smoking status)
3
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NCT02169037
1:25:chronic_disease
Congestive heart failure (1 point)
3
[ "Congestive", "heart", "failure", "(", "1", "point", ")" ]
[ 2, 2, 2, 0, 0, 0, 0 ]
NCT02456857
81:120:chronic_disease,158:173:chronic_disease,177:235:chronic_disease,237:250:chronic_disease,259:268:chronic_disease,270:297:chronic_disease,303:331:chronic_disease,351:374:chronic_disease,442:467:chronic_disease,482:505:chronic_disease,540:571:chronic_disease,,,,,741:759:chronic_disease,764:801:chronic_disease
Patients who have any severe and/or uncontrolled medical conditions such as: a. serious uncontrolled cardiac arrhythmia, or any other clinically significant cardiac disease b. active (acute or chronic) or uncontrolled severe infection, liver disease such as cirrhosis, decompensated liver disease, and active and chronic hepatitis (i.e. quantifiable hepatitis B virus [HBV]-deoxyribonucleic acid [DNA] and/or positive surface antigen of the hepatitis B virus [HBsAg], quantifiable hepatitis C virus [HCV]-ribonucleic acid [RNA]), c. known severely impaired lung function (spirometry and Diffusing capacity of the lungs for carbon monoxide [DLCO] 50% or less of normal and oxygen (O2) saturation 88% or less at rest on room air), d. active, bleeding diathesis; e. Moderate or severe hepatic impairment (Child-Pugh B or C)
3
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NCT02389309
61:83:chronic_disease,94:106:treatment,117:136:treatment,138:157:chronic_disease
Uncontrolled current illness including, but not limited to, uncontrolled infection, need for hemodialysis, need for ventilatory support, psychiatric illness/social situations that would limit compliance with study requirements
3
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NCT01895777
31:51:treatment,
Patients who have received an investigational drug in the past 30 days prior to screening
3
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NCT02276716
17:22:treatment,24:30:treatment,34:55:treatment
Patients taking ginko, garlic or vitamin E supplements
3
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[ 0, 0, 1, 0, 1, 0, 1, 1, 1 ]
NCT00630565
41:69:chronic_disease,130:134:treatment,141:170:treatment
The patient must be free of symptoms of uncontrolled cardiac disease, and must not have compromised cardiac function detected by ECHO or by gated cardiac blood flow scan
3
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NCT03085485
1:19:treatment
herbal medications
3
[ "herbal", "medications" ]
[ 1, 1 ]
NCT02021279
16:22:chronic_disease,26:52:chronic_disease,67:88:chronic_disease,90:119:chronic_disease,124:139:chronic_disease
Subject has an active or chronic systemic infection including any gynecologic infection, urinary tract infection (UTI), or tissue necrosis
3
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NCT02960555
1:14:treatment,
Major surgery within 1 month prior to enrollment
3
[ "Major", "surgery", "within", "1", "month", "prior", "to", "enrollment" ]
[ 1, 1, 0, 0, 0, 0, 0, 0 ]
NCT03037983
1:13:treatment
clomipramine
3
[ "clomipramine" ]
[ 1 ]
NCT01421810
34:48:chronic_disease,
Subjects with adequately treated hypothyroidism, reflected by normal TSH values
3
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[ 0, 0, 0, 0, 2, 0, 0, 0, 0, 0, 0 ]
NCT01903330
1:12:chronic_disease,16:27:chronic_disease,41:53:chronic_disease
Hepatitis B or Hepatitis C Uncontrolled hypertension
3
[ "Hepatitis", "B", "or", "Hepatitis", "C", "Uncontrolled", "hypertension" ]
[ 2, 2, 0, 0, 0, 0, 2 ]
NCT00919503
20:40:chronic_disease
DONOR: With active infectious hepatitis
3
[ "DONOR", ":", "With", "active", "infectious", "hepatitis" ]
[ 0, 0, 0, 0, 2, 2 ]
NCT00467987
1:15:chronic_disease,19:28:treatment,30:51:chronic_disease,53:68:chronic_disease,70:92:treatment,94:101:treatment,105:125:treatment,,,
Coronary event or procedure (myocardial infarction, unstable angina, coronary artery bypass, surgery or coronary angioplasty) in the previous four weeks; 2)Hemoglobin A1c >10%
3
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NCT00147056
1:32:treatment
Anti-arrhythmic drug medication
3
[ "Anti-arrhythmic", "drug", "medication" ]
[ 1, 1, 1 ]
NCT03007030
1:23:treatment,
whole pelvic radiation is considered to be over 25%
3
[ "whole", "pelvic", "radiation", "is", "considered", "to", "be", "over", "25", "%" ]
[ 1, 1, 1, 0, 0, 0, 0, 0, 0, 0 ]
NCT02993406
34:62:chronic_disease,73:96:chronic_disease,98:137:chronic_disease,139:178:chronic_disease
History of, or at high risk for, cardiovascular disease (CVD) including coronary artery disease, symptomatic peripheral arterial disease, cerebrovascular atherosclerotic disease
3
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NCT02539160
4:13:treatment,28:35:treatment,51:62:treatment
On treatment with low-dose aspirin (81mg/day) and clopidogrel (75mg/day)
3
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NCT02516813
35:48:chronic_disease,66:90:chronic_disease,157:160:treatment,169:216:treatment
History of difficulty swallowing, malabsorption or other chronic gastrointestinal disease or conditions that may hamper compliance and/or absorption of the IMP, use of percutaneous endoscopic gastrostomy (PEG) tubes
3
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NCT02462590
11:42:treatment
receiving invasive mechanical ventilation
3
[ "receiving", "invasive", "mechanical", "ventilation" ]
[ 0, 1, 1, 1 ]
NCT02844907
1:24:chronic_disease
Coronary artery disease
3
[ "Coronary", "artery", "disease" ]
[ 2, 2, 2 ]
NCT02108860
59:78:chronic_disease
Current clinical, radiographic, or laboratory evidence of active tuberculosis
3
[ "Current", "clinical", ",", "radiographic", ",", "or", "laboratory", "evidence", "of", "active", "tuberculosis" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 2, 2 ]
NCT02557321
27:37:treatment,
the subject is not taking prednisone at >10 mg or equivalent daily
3
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[ 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0 ]
NCT02307565
1:14:treatment,
Major surgery in the last 30 days
3
[ "Major", "surgery", "in", "the", "last", "30", "days" ]
[ 1, 1, 0, 0, 0, 0, 0 ]
NCT02819635
1:26:chronic_disease,,,
Active ulcerative colitis with an Adapted Mayo score of 5 to 9 points
3
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[ 2, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT03078907
15:39:treatment,81:96:treatment,100:114:treatment
Patients on a PAH-specific monotherapy targeting the nitric oxide pathway (i.e. PDE-5 inhibitor or sGC stimulator)
3
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[ 0, 0, 0, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 1, 1, 0, 1, 1, 0 ]
NCT02385110
,,,,,251:261:treatment
Male patients with female partners who are of childbearing potential: Recommendation is for male and partner to use at least 2 effective contraceptive methods, as described above, prior to study entry and for at least 3 months after the last dose of study drug
3
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NCT03122912
12:37:chronic_disease,39:65:chronic_disease,67:93:chronic_disease,96:106:chronic_disease
History of photosensitive conditions (connective tissue diseases, polymorphous light eruption, porphyrias etc)
3
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NCT00967785
,,,,137:147:treatment
Willingness to interrupt medications to raise the white count (WBC) such as G-CSF or GM-CSF for at least 1 week before and while on the study drug
3
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NCT02343549
13:31:chronic_disease,35:47:chronic_disease,67:94:treatment
Evidence of bleeding diathesis or coagulopathy (in the absence of therapeutic anticoagulation)
3
[ "Evidence", "of", "bleeding", "diathesis", "or", "coagulopathy", "(", "in", "the", "absence", "of", "therapeutic", "anticoagulation", ")" ]
[ 0, 0, 2, 2, 0, 2, 0, 0, 0, 0, 0, 1, 1, 0 ]
NCT02520778
24:49:treatment
prior treatment with a third-generation EGFR TKI is allowed for the dose escalation phase, but is not permitted for the expansion cohort
3
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NCT03035474
1:17:chronic_disease,29:31:chronic_disease,41:51:cancer,,
Terminal illness other than HF, such as malignancy, or with a life expectancy of less than 1 year as determined by the enrolling clinician-investigator
3
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NCT03171480
1:23:treatment,67:73:chronic_disease,82:93:chronic_disease,95:116:chronic_disease,127:139:chronic_disease
Isosorbide mononitrate should not be used in patients with severe anemia, severe hypotension, closed angle glaucoma or severe hypovolaemia
3
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NCT01174121
8:27:chronic_disease,38:62:treatment,64:85:chronic_disease,130:147:chronic_disease
Active systemic infections requiring anti-infective treatment, coagulation disorders, or any other active or uncompensated major medical illnesses
3
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NCT01807117
17:19:cancer,25:31:cancer,178:195:cancer,214:227:cancer,249:266:cancer
Either having a T3 (the cancer has grown through the muscularis propria and into the outermost layers of the colon or rectum but not through them) or higher, node positivity or metastatic lesion in the context of rectal cancer or being studied for colorectal cancer follow up, independent of the renal function
3
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NCT02453373
1:20:chronic_disease
Sickle cell disease
3
[ "Sickle", "cell", "disease" ]
[ 2, 2, 2 ]
NCT02510456
10:20:cancer,33:43:cancer,47:82:cancer,86:103:cancer,
Previous malignancy, other than basal cell or squamous cell carcinoma of the skin or in situ carcinoma of the cervix, from which the patient has been disease free for less than 5 years
3
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NCT01532687
,37:47:treatment
for 6 months prior to first dose of study drug
3
[ "for", "6", "months", "prior", "to", "first", "dose", "of", "study", "drug" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 1, 1 ]
NCT02427841
5:18:treatment,20:32:treatment,34:43:treatment,47:54:treatment,60:85:cancer,97:118:treatment
Any prior therapy (chemotherapy, radiation or surgery) for pancreatic adenocarcinoma other than biliary decompression
3
[ "Any", "prior", "therapy", "(", "chemotherapy", ",", "radiation", "or", "surgery", ")", "for", "pancreatic", "adenocarcinoma", "other", "than", "biliary", "decompression" ]
[ 0, 1, 1, 0, 1, 0, 1, 0, 1, 0, 0, 3, 3, 0, 0, 1, 1 ]
NCT02465268
,,,,176:186:treatment
Women of childbearing potential and male participants must be willing to practice adequate contraception throughout the study and for at least 24 weeks after the last dose of study drug
3
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NCT02169739
39:41:chronic_disease,45:56:chronic_disease,58:85:chronic_disease
High risk of bleeding (e.g. recurrent GI or GU bleeding, active peptic ulcer disease, etc.)
3
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NCT03004287
,81:100:treatment,107:134:treatment,136:175:treatment,177:198:treatment,203:222:treatment
Patients must be either untreated or have not received more than four cycles of systemic MM therapy (e.g. Revlimid Dexamethasone (RD), Bortezomib Revlimid Dexamethasone (VRD). Prior bisphosphonates and localized radiation are allowed
3
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