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NCT02439060
|
1:15:cancer,28:46:treatment,51:74:treatment
|
Bladder cancer, undergoing radical cystectomy and ileal conduit diversion
| 3
|
[
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NCT02547818
|
,,169:192:chronic_disease
|
Abnormal pulmonary function test, defined for this protocol as: FEV1/FVC < predicted value for subject AND FEV1 < 70% of predicted value, indicating moderate or severe respiratory obstruction
| 3
|
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NCT01676259
|
1:22:chronic_disease,
|
myocardial infarction within 4months prior to Day 1
| 3
|
[
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"within",
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[
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0,
0,
0,
0
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NCT03113695
|
10:19:chronic_disease
|
Positive hepatitis serology
| 3
|
[
"Positive",
"hepatitis",
"serology"
] |
[
0,
2,
0
] |
NCT02474927
|
22:31:chronic_disease
|
Known Child-Pugh B/C cirrhosis
| 3
|
[
"Known",
"Child-Pugh",
"B/C",
"cirrhosis"
] |
[
0,
0,
0,
2
] |
NCT03071692
|
38:57:treatment,,,,,,
|
Initiation of, or change in, current TG-lowering therapy within 12 weeks of Visit 1 (if applicable). Note: TG-lowering therapy is defined as niacin > 100 mg/day or dietary supplements or prescription omega-3 fatty acids > 1 g/day
| 3
|
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NCT01962415
|
1:29:chronic_disease
|
Sanfilippo syndrome (MPS II)
| 3
|
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NCT02553941
|
1:19:treatment,30:42:treatment,44:57:treatment,59:71:treatment,73:112:treatment,
|
Anticancer therapy including chemotherapy, immunotherapy, radiotherapy, hormonal or any investigational therapy within 14 days or 5 half-lives prior to first dose of study drug
| 3
|
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NCT02977299
|
43:47:treatment,49:61:treatment,63:94:treatment,99:110:treatment
|
patients who have received treatment with rTMS, aripiprazole, electroconvulsive therapy (ECT), or venlafaxine during the current episode
| 3
|
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NCT02924402
|
1:17:cancer,18:38:cancer,42:77:cancer
|
Multiple myeloma/plasma cell leukemia or B cell acute lymphoblastic leukemia
| 3
|
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NCT02737475
|
32:44:treatment
|
All subjects must have a fresh tumor biopsy
| 3
|
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NCT01964404
|
8:16:treatment,
|
Use of cannabis within the month prior to screening
| 3
|
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"cannabis",
"within",
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NCT02826681
|
12:27:chronic_disease,29:42:chronic_disease,50:72:chronic_disease,76:101:chronic_disease
|
History of hemochromatosis, hemosiderosis, other iron storage disorders or iron metabolism disorders
| 3
|
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NCT01505062
|
,24:49:chronic_disease
|
caused by at least one pathogenic MYO7A mutation on both alleles
| 3
|
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"caused",
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NCT02579096
|
1:8:chronic_disease
|
Ascites
| 3
|
[
"Ascites"
] |
[
2
] |
NCT02291978
|
22:37:chronic_disease
|
Patients with severe lumbar lordosis
| 3
|
[
"Patients",
"with",
"severe",
"lumbar",
"lordosis"
] |
[
0,
0,
0,
2,
2
] |
NCT02304458
|
47:67:cancer
|
Part D5: Patients with relapsed or refractory non-Hodgkin lymphoma
| 3
|
[
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NCT02910648
|
1:5:allergy_name
|
Food allergies
| 3
|
[
"Food",
"allergies"
] |
[
4,
0
] |
NCT01697293
|
62:90:cancer,,
|
Patients must have histologically or cytologically confirmed adenocarcinoma of the breast associated with clinical stage: IV (see American Joint Committee on Cancer [AJCC] staging criteria, 7th edition) or stage IIB-IIIC (expansion cohort only)
| 3
|
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NCT01734512
|
79:89:treatment,,
|
Because no dosing or adverse event data are currently available on the use of everolimus in patients <3 years of age,
| 3
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NCT02176161
|
7:19:cancer,
|
other solid tumors curatively treated with no evidence of disease for at least 5 years
| 3
|
[
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NCT02769611
|
61:72:chronic_disease
|
Patients with hemodynamic instability or significant active arrhythmias
| 3
|
[
"Patients",
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"instability",
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"significant",
"active",
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[
0,
0,
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0,
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2
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NCT02393794
|
20:37:treatment
|
Concomitant use of CYP3A4 inhibitors
| 3
|
[
"Concomitant",
"use",
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"CYP3A4",
"inhibitors"
] |
[
0,
0,
0,
1,
1
] |
NCT02488967
|
1:26:chronic_disease,,,,
|
Uncontrolled hypertension defined as sustained systolic blood pressure (BP) > 150 mmHg or diastolic BP > 90 mmHg
| 3
|
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NCT02317991
|
15:40:treatment
|
Patients with prior taxane chemotherapy
| 3
|
[
"Patients",
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"chemotherapy"
] |
[
0,
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1,
1,
1
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NCT02501733
|
1:25:chronic_disease
|
avascular necrosis (AVN)
| 3
|
[
"avascular",
"necrosis",
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"AVN",
")"
] |
[
2,
2,
2,
0,
0
] |
NCT01920061
|
1:13:treatment,15:27:treatment,29:38:treatment,42:63:treatment,
|
Chemotherapy, radiotherapy, biologics or investigational agent within 4 weeks of the lead-in dose
| 3
|
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NCT01505569
|
1:4:treatment
|
MRI evidence
| 3
|
[
"MRI",
"evidence"
] |
[
1,
0
] |
NCT01269853
|
41:74:chronic_disease
|
Patients with significant inter-current medical or psychiatric conditions that would place them at increased risk or affect their ability to receive or comply with treatment or post-treatment clinical monitoring
| 3
|
[
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NCT02995330
|
7:16:treatment,22:34:treatment,36:46:treatment,48:60:treatment,65:77:treatment
|
Prior treatment with Sipuleucel-T, radium-223, strontium-89, or samarium-153
| 3
|
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NCT02336451
|
,76:86:treatment
|
Be neurologically stable within at least 1 week prior to the first dose of study drug
| 3
|
[
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NCT02370056
|
1:19:treatment
|
Elective procedure
| 3
|
[
"Elective",
"procedure"
] |
[
1,
1
] |
NCT02514915
|
1:4:treatment,26:42:cancer,50:59:treatment
|
MRI scan consistent with brain metastasis as per radiology report
| 3
|
[
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NCT02905370
|
1:25:chronic_disease
|
Depression/mental health
| 3
|
[
"Depression/mental",
"health"
] |
[
2,
2
] |
NCT02989597
|
22:47:treatment
|
Treatment with other NMDA receptor antagonists
| 3
|
[
"Treatment",
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"antagonists"
] |
[
0,
0,
0,
1,
1,
1
] |
NCT01994382
|
40:48:chronic_disease,50:68:chronic_disease,91:101:chronic_disease
|
previous drug-related toxicity (except alopecia, erectile impotence, hot flashes, libido, neuropathy)
| 3
|
[
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NCT02454010
|
18:43:cancer
|
Expansion Phase: P-cadherin positive tumor expression
| 3
|
[
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[
0,
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3,
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NCT03023930
|
32:40:treatment
|
Patients who test positive for fentanyl only are not eligible due to lack of uniformly available rapid urine tests
| 3
|
[
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NCT02273362
|
,134:150:treatment
|
Willingness to discontinue smoking during the study two weeks prior to beginning the study and willingness to not smoke while taking study medication
| 3
|
[
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NCT02393794
|
17:30:treatment
|
Subject has had major surgery
| 3
|
[
"Subject",
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"major",
"surgery"
] |
[
0,
0,
0,
1,
1
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NCT02323100
|
1:34:chronic_disease,,53:81:chronic_disease,92:115:treatment,
|
Acute upper respiratory infection within 2 weeks or acute pulmonary exacerbation requiring intravenous antibiotics within 4 weeks of Screening Visit
| 3
|
[
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NCT01827384
|
79:116:chronic_disease,182:206:chronic_disease,208:223:chronic_disease,234:252:chronic_disease,254:275:chronic_disease,,298:324:chronic_disease,358:387:chronic_disease,389:402:chronic_disease,422:449:chronic_disease,466:483:chronic_disease,504:527:chronic_disease,504:515:chronic_disease,598:621:chronic_disease
|
Patients with uncontrolled intercurrent illness including, but not limited to psychiatric illness/social situations that would limit compliance with study requirements, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, myocardial infarction in the past 6 months, invasive fungal infections, or active (acute or chronic) or uncontrolled severe infection, liver disease such as cirrhosis, decompensated liver disease, and active and chronic hepatitis (i.e., quantifiable hepatitis B virus [HBV]-DNA and/or positive hepatitis B surface antigen [HbsAg], quantifiable hepatitis C virus [HCV]-ribonucleic acid [RNA])
| 3
|
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NCT00737893
|
53:59:chronic_disease
|
The patient has a history of heart problems such as angina
| 3
|
[
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NCT02496208
|
15:24:chronic_disease,35:53:treatment,44:53:treatment,
|
Severe active infection requiring systemic treatment within 14 days before the first dose of study treatment
| 3
|
[
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NCT01795573
|
1:4:cancer,6:9:cancer,,,,,134:142:cancer,
|
AML, ALL: Normal values for absolute neutrophil count (>1000/microL) and platelet count (>100,000/microL); Absence of extramedullary leukemia; Less than 5 percent blast cells present in the bone marrow
| 3
|
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NCT03054519
|
1:23:chronic_disease,,
|
Chronic kidney disease defined as GFR <45
| 3
|
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[
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NCT00857207
|
31:35:chronic_disease
|
2 incidences of blast-related mTBI according to the American Congress of Rehabilitation Medicine
| 3
|
[
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NCT02013492
|
16:27:treatment
|
The effects of propranolol on the developing human fetus may be detrimental
| 3
|
[
"The",
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NCT01851694
|
1:12:treatment
|
Recent OGTT consistent with Indeterminate-GT, IGT, CFRD w/o fasting hyperglycemia
| 3
|
[
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",",
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0
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NCT02278315
|
,,,,166:176:treatment
|
Women of childbearing potential and men who are able to father a child, must agree to use an effective contraception method during study and for 12 months following study drug administration
| 3
|
[
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NCT02161380
|
58:70:treatment
|
A previous CLIA certified genetic lab result showing the LHON G11778A mutation will be accepted for inclusion
| 3
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NCT02574910
|
,,,94:108:treatment
|
Morning serum androstenedione concentrations >1.5 x ULN after 7 days of dosing with doses of hydrocortisone required for physiologic replacement
| 3
|
[
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NCT02106052
|
42:44:chronic_disease
|
Physician confirmed, clinically definite MS diagnosis as defined by the revised McDonald criteria
| 3
|
[
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NCT02020707
|
27:34:cancer,36:45:cancer,51:68:cancer,77:83:cancer,85:95:cancer,97:109:cancer,111:119:cancer,121:138:cancer,140:156:cancer,158:163:cancer,169:183:cancer
|
allowable histologies for ovarian, fallopian, and peritoneal cancer include serous, clear cell, endometrioid, mucinous, transitional cell, undifferentiated, mixed, and carcinosarcoma
| 3
|
[
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NCT02464878
|
,,,170:191:treatment,210:221:treatment,225:234:chronic_disease
|
Stable renal function as defined by a creatinine of no more than one third greater than the average creatinine determination performed in the 3 previous months prior to islet transplantation, until rejection, obstruction or infection is ruled out
| 3
|
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NCT01515527
|
1:30:treatment,20:30:treatment,93:96:cancer
|
Prior therapy with decitabine will be allowed unless the patient experienced progression to AML while being treated with decitabine
| 3
|
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NCT02990481
|
1:22:chronic_disease,
|
myocardial infarction within the past 6 months
| 3
|
[
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] |
[
2,
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0,
0,
0,
0
] |
NCT02930018
|
156:176:treatment
|
No femoral pulses, very difficult endovascular access or extreme tortuosity of great vessels that is predicted to result in an inability to deliver timely endovascular therapy
| 3
|
[
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NCT02350764
|
26:38:cancer
|
Have a safely biopsiable tumor lesion
| 3
|
[
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"tumor",
"lesion"
] |
[
0,
0,
0,
0,
3,
3
] |
NCT02712736
|
15:27:cancer
|
Patients with malignancies
| 3
|
[
"Patients",
"with",
"malignancies"
] |
[
0,
0,
3
] |
NCT02393690
|
45:62:cancer
|
Histological or cytological confirmation of thyroid carcinoma of follicular origin (including papillary, follicular, or poorly differentiated subtypes and their respective variants)
| 3
|
[
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"cytological",
"confirmation",
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"of",
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",",
"follicular",
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NCT02538198
|
1:8:treatment,,,24:32:treatment,54:61:treatment,71:82:treatment
|
aspirin (81 or 325 mg) warfarin low molecular weight heparin or other medications as clinically indicated
| 3
|
[
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NCT02312518
|
5:10:chronic_disease,,
|
the ulcer size must be between 2 cm2 and 200 cm2
| 3
|
[
"the",
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[
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0,
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NCT02515708
|
21:50:treatment
|
Patients undergoing primary liver transplantation
| 3
|
[
"Patients",
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"liver",
"transplantation"
] |
[
0,
0,
1,
1,
1
] |
NCT02213913
|
7:10:chronic_disease
|
Known CNS involvement
| 3
|
[
"Known",
"CNS",
"involvement"
] |
[
0,
2,
0
] |
NCT02315196
|
9:39:chronic_disease,51:68:chronic_disease,72:89:chronic_disease,100:123:treatment
|
Serious concomitant systemic disorders (including active infections or chronic infection requiring suppressive antibiotics) that would compromise the safety of the patient or compromise the patient's ability to complete the study, at the discretion of the investigator
| 3
|
[
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NCT01999179
|
16:28:treatment
|
Treatment with thrombolysis
| 3
|
[
"Treatment",
"with",
"thrombolysis"
] |
[
0,
0,
1
] |
NCT02903446
|
1:14:chronic_disease
|
Hypercalcemia
| 3
|
[
"Hypercalcemia"
] |
[
2
] |
NCT02369653
|
5:25:treatment
|
Any investigational drug being administered during the study
| 3
|
[
"Any",
"investigational",
"drug",
"being",
"administered",
"during",
"the",
"study"
] |
[
0,
1,
1,
0,
0,
0,
0,
0
] |
NCT00959140
|
1:8:chronic_disease
|
Cardiac
| 3
|
[
"Cardiac"
] |
[
2
] |
NCT02416102
|
11:32:chronic_disease
|
Untreated arterial hypertension
| 3
|
[
"Untreated",
"arterial",
"hypertension"
] |
[
0,
2,
2
] |
NCT02574728
|
29:49:treatment
|
Currently receiving another investigational drug
| 3
|
[
"Currently",
"receiving",
"another",
"investigational",
"drug"
] |
[
0,
0,
0,
1,
1
] |
NCT02339948
|
1:15:treatment
|
Hip prosthesis
| 3
|
[
"Hip",
"prosthesis"
] |
[
1,
1
] |
NCT02762773
|
27:45:treatment
|
Patients with who require general anesthetic
| 3
|
[
"Patients",
"with",
"who",
"require",
"general",
"anesthetic"
] |
[
0,
0,
0,
0,
1,
1
] |
NCT03112590
|
1:14:treatment,
|
Major surgery within 4 weeks of initiation of study drug
| 3
|
[
"Major",
"surgery",
"within",
"4",
"weeks",
"of",
"initiation",
"of",
"study",
"drug"
] |
[
1,
1,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT02971202
|
,,51:75:chronic_disease
|
>= 1 episode in the past 3 months or diagnosis of hypoglycemia unawareness
| 3
|
[
">",
"=",
"1",
"episode",
"in",
"the",
"past",
"3",
"months",
"or",
"diagnosis",
"of",
"hypoglycemia",
"unawareness"
] |
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
2,
2
] |
NCT03068780
|
8:28:treatment,
|
Use of systemic antibiotics for wound-related infections within 7 days prior to enrolment
| 3
|
[
"Use",
"of",
"systemic",
"antibiotics",
"for",
"wound-related",
"infections",
"within",
"7",
"days",
"prior",
"to",
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] |
[
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT03146442
|
1:10:chronic_disease,12:20:chronic_disease,29:55:chronic_disease
|
Metabolic, hormonal, and/or neural conditions/diseases that influence metabolism or appetite
| 3
|
[
"Metabolic",
",",
"hormonal",
",",
"and/or",
"neural",
"conditions/diseases",
"that",
"influence",
"metabolism",
"or",
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[
2,
0,
2,
0,
0,
2,
2,
0,
0,
0,
0,
0
] |
NCT03058029
|
12:37:chronic_disease
|
History of gastric or duodenal ulcer
| 3
|
[
"History",
"of",
"gastric",
"or",
"duodenal",
"ulcer"
] |
[
0,
0,
2,
2,
2,
2
] |
NCT02314377
|
22:25:treatment
|
Inability to undergo MRI scans
| 3
|
[
"Inability",
"to",
"undergo",
"MRI",
"scans"
] |
[
0,
0,
0,
1,
0
] |
NCT01553942
|
6:44:cancer
|
Have lung cancer harboring an EGFR mutation
| 3
|
[
"Have",
"lung",
"cancer",
"harboring",
"an",
"EGFR",
"mutation"
] |
[
0,
3,
3,
3,
3,
3,
3
] |
NCT02452008
|
6:53:cancer
|
Have metastatic castration-resistant prostate cancer
| 3
|
[
"Have",
"metastatic",
"castration-resistant",
"prostate",
"cancer"
] |
[
0,
3,
3,
3,
3
] |
NCT02429934
|
30:53:treatment
|
Inability to self-administer subcutaneous injections, to comply with instructions, or to keep appointments for study visits
| 3
|
[
"Inability",
"to",
"self-administer",
"subcutaneous",
"injections",
",",
"to",
"comply",
"with",
"instructions",
",",
"or",
"to",
"keep",
"appointments",
"for",
"study",
"visits"
] |
[
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT03123783
|
1:18:cancer,20:25:cancer,29:40:cancer,,81:96:cancer
|
Second malignancy (solid or hematologic) within the past 3 years except locally curable cancers that have been apparently cured
| 3
|
[
"Second",
"malignancy",
"(",
"solid",
"or",
"hematologic",
")",
"within",
"the",
"past",
"3",
"years",
"except",
"locally",
"curable",
"cancers",
"that",
"have",
"been",
"apparently",
"cured"
] |
[
3,
3,
0,
3,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
3,
3,
0,
0,
0,
0,
0
] |
NCT00929006
|
13:25:chronic_disease,33:62:chronic_disease,64:86:chronic_disease,88:101:chronic_disease
|
Evidence of virilization (e.g., rapidly progressive hirsutism, deepening of the voice, clitoromegaly)
| 3
|
[
"Evidence",
"of",
"virilization",
"(",
"e.g.",
",",
"rapidly",
"progressive",
"hirsutism",
",",
"deepening",
"of",
"the",
"voice",
",",
"clitoromegaly",
")"
] |
[
0,
0,
2,
0,
0,
0,
2,
2,
2,
0,
2,
2,
2,
2,
0,
2,
0
] |
NCT02389959
|
17:46:treatment,54:75:treatment,77:95:chronic_disease
|
actively taking immunosuppressive medications due to organ transplantation, rheumatoid disease, or other medical conditions
| 3
|
[
"actively",
"taking",
"immunosuppressive",
"medications",
"due",
"to",
"organ",
"transplantation",
",",
"rheumatoid",
"disease",
",",
"or",
"other",
"medical",
"conditions"
] |
[
0,
0,
1,
1,
0,
0,
1,
1,
0,
2,
2,
0,
0,
0,
0,
0
] |
NCT02606396
|
7:55:treatment
|
Prior esophageal or gastro-esophageal junction surgery
| 3
|
[
"Prior",
"esophageal",
"or",
"gastro-esophageal",
"junction",
"surgery"
] |
[
0,
1,
1,
1,
1,
1
] |
NCT02566395
|
1:25:cancer
|
Myelodysplastic syndrome
| 3
|
[
"Myelodysplastic",
"syndrome"
] |
[
3,
3
] |
NCT02191098
|
9:25:chronic_disease
|
Chronic hepatitis B or C
| 3
|
[
"Chronic",
"hepatitis",
"B",
"or",
"C"
] |
[
0,
2,
2,
2,
2
] |
NCT02191098
|
26:48:treatment,
|
Intended modification of antiretroviral therapy in the next 24 weeks
| 3
|
[
"Intended",
"modification",
"of",
"antiretroviral",
"therapy",
"in",
"the",
"next",
"24",
"weeks"
] |
[
0,
0,
0,
1,
1,
0,
0,
0,
0,
0
] |
NCT02484404
|
1:4:chronic_disease,8:11:chronic_disease,82:97:chronic_disease,108:116:treatment
|
HBV-or HCV-positive patients are ineligible because of potential reactivation of hepatitis virus following steroids
| 3
|
[
"HBV-or",
"HCV-positive",
"patients",
"are",
"ineligible",
"because",
"of",
"potential",
"reactivation",
"of",
"hepatitis",
"virus",
"following",
"steroids"
] |
[
2,
2,
0,
0,
0,
0,
0,
0,
0,
0,
2,
2,
0,
1
] |
NCT02315612
|
15:18:chronic_disease,44:61:chronic_disease,80:106:treatment
|
Patients with HIV are at increased risk of lethal infections when treated with marrow-suppressive therapy
| 3
|
[
"Patients",
"with",
"HIV",
"are",
"at",
"increased",
"risk",
"of",
"lethal",
"infections",
"when",
"treated",
"with",
"marrow-suppressive",
"therapy"
] |
[
0,
0,
2,
0,
0,
0,
0,
0,
2,
2,
0,
0,
0,
1,
1
] |
NCT02891850
|
1:32:chronic_disease
|
Connective tissue disease (CTD)
| 3
|
[
"Connective",
"tissue",
"disease",
"(",
"CTD",
")"
] |
[
2,
2,
2,
2,
0,
0
] |
NCT01789281
|
53:63:treatment
|
Patient is currently benefiting from treatment with everolimus, as determined by the guidelines of the parent protocol
| 3
|
[
"Patient",
"is",
"currently",
"benefiting",
"from",
"treatment",
"with",
"everolimus",
",",
"as",
"determined",
"by",
"the",
"guidelines",
"of",
"the",
"parent",
"protocol"
] |
[
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT01620216
|
1:25:chronic_disease
|
Congestive heart failure
| 3
|
[
"Congestive",
"heart",
"failure"
] |
[
2,
2,
2
] |
NCT02875301
|
1:12:treatment
|
angioplasty
| 3
|
[
"angioplasty"
] |
[
1
] |
NCT02457845
|
,35:51:treatment
|
Patients must be ≥ 3 months since transplant prior to study entry
| 3
|
[
"Patients",
"must",
"be",
"≥",
"3",
"months",
"since",
"transplant",
"prior",
"to",
"study",
"entry"
] |
[
0,
0,
0,
0,
0,
0,
0,
1,
1,
0,
0,
0
] |
NCT02171104
|
1:23:chronic_disease
|
MPS VII (Sly syndrome)
| 3
|
[
"MPS",
"VII",
"(",
"Sly",
"syndrome",
")"
] |
[
2,
2,
2,
2,
0,
0
] |
NCT02236000
|
1:40:treatment
|
resection of the stomach or small bowel
| 3
|
[
"resection",
"of",
"the",
"stomach",
"or",
"small",
"bowel"
] |
[
1,
1,
1,
1,
1,
1,
1
] |
NCT02551679
|
1:45:chronic_disease
|
Lower extremity non-treated active infection
| 3
|
[
"Lower",
"extremity",
"non-treated",
"active",
"infection"
] |
[
2,
2,
2,
2,
2
] |
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