Datasets:
SKT27182
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Dataset card Data Studio Files
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NCT01908777
1:47:cancer
Subcutaneous panniculitis-like T-cell lymphoma
3
[ "Subcutaneous", "panniculitis-like", "T-cell", "lymphoma" ]
[ 3, 3, 3, 3 ]
NCT03153319
1:27:treatment,
Immune suppression therapy less than 1 year prior to enrollment
3
[ "Immune", "suppression", "therapy", "less", "than", "1", "year", "prior", "to", "enrollment" ]
[ 1, 1, 1, 0, 0, 0, 0, 0, 0, 0 ]
NCT01554371
59:69:allergy_name
Patients with known hypersensitivity to the components of study drug or its analogs
3
[ "Patients", "with", "known", "hypersensitivity", "to", "the", "components", "of", "study", "drug", "or", "its", "analogs" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 4, 4, 0, 0, 0 ]
NCT02925923
1:13:treatment
Voriconazole
3
[ "Voriconazole" ]
[ 1 ]
NCT02595372
75:89:allergy_name
Known hypersensitivity to any component of the formulation or substituted benzimidazoles
3
[ "Known", "hypersensitivity", "to", "any", "component", "of", "the", "formulation", "or", "substituted", "benzimidazoles" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 4 ]
NCT01639508
,,52:77:treatment
Absolute neutrophil count (ANC) ≥ 1500/mm3 without colony stimulating factor support
3
[ "Absolute", "neutrophil", "count", "(", "ANC", ")", "≥", "1500/mm3", "without", "colony", "stimulating", "factor", "support" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 1, 1, 0 ]
NCT01130077
43:49:chronic_disease,82:94:treatment,111:120:treatment
Newly diagnosed, non-brainstem high-grade glioma* Patients may not have received chemotherapy during or after radiation
3
[ "Newly", "diagnosed", ",", "non-brainstem", "high-grade", "glioma", "*", "Patients", "may", "not", "have", "received", "chemotherapy", "during", "or", "after", "radiation" ]
[ 0, 0, 0, 0, 0, 2, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1 ]
NCT01841333
1:24:chronic_disease
Grade III/IV acute GVHD
3
[ "Grade", "III/IV", "acute", "GVHD" ]
[ 2, 2, 2, 2 ]
NCT00739362
1:26:cancer,19:26:cancer,143:166:cancer
non-melanoma skin cancers or cancers that have clearly been cured or, in the opinion of the investigator, carry an excellent prognosis (e.g., Stage 1 cervical cancer)
3
[ "non-melanoma", "skin", "cancers", "or", "cancers", "that", "have", "clearly", "been", "cured", "or", ",", "in", "the", "opinion", "of", "the", "investigator", ",", "carry", "an", "excellent", "prognosis", "(", "e.g.", ",", "Stage", "1", "cervical", "cancer", ")" ]
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NCT02139436
13:24:chronic_disease
significant arrhythmias
3
[ "significant", "arrhythmias" ]
[ 0, 2 ]
NCT02746458
1:21:chronic_disease
Impaired circulation
3
[ "Impaired", "circulation" ]
[ 2, 2 ]
NCT02181257
,41:51:treatment,75:103:treatment,133:141:treatment,149:159:treatment,,,283:307:chronic_disease
any patient who at least one year after transplant is treated with either lymphocyte depleting therapy or with an escalated dose of steroids (i.e., prednisone greater than 30 mg/day) for more than one month for an acute decline in lung function that is suspected to be secondary to acute cellular rejection
3
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NCT02928991
1:23:chronic_disease
Dyskeratosis Congenita
3
[ "Dyskeratosis", "Congenita" ]
[ 2, 2 ]
NCT01690468
7:21:treatment
Prior TCN-PM therapy
3
[ "Prior", "TCN-PM", "therapy" ]
[ 0, 1, 1 ]
NCT01697371
1:11:cancer,
Metastases location within 2cm of GI tract
3
[ "Metastases", "location", "within", "2cm", "of", "GI", "tract" ]
[ 3, 0, 0, 0, 0, 0, 0 ]
NCT02579044
21:31:treatment
currently receiving lonafarnib under protocol 09-06-0298
3
[ "currently", "receiving", "lonafarnib", "under", "protocol", "09-06-0298" ]
[ 0, 0, 1, 0, 0, 0 ]
NCT02480114
20:51:treatment
Planned primary or adjuvant chemoradiation therapy
3
[ "Planned", "primary", "or", "adjuvant", "chemoradiation", "therapy" ]
[ 0, 0, 0, 1, 1, 1 ]
NCT01532687
,14:27:treatment,29:38:treatment,61:72:chronic_disease,,
Male partner sterilization (vasectomy with documentation of azoospermia) prior to the female subject's entry into the study, and this male is the sole partner for that subject
3
[ "Male", "partner", "sterilization", "(", "vasectomy", "with", "documentation", "of", "azoospermia", ")", "prior", "to", "the", "female", "subject", "'s", "entry", "into", "the", "study", ",", "and", "this", "male", "is", "the", "sole", "partner", "for", "that", "subject" ]
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NCT02505984
12:39:chronic_disease
At risk of postpartum depression (PPD)
3
[ "At", "risk", "of", "postpartum", "depression", "(", "PPD", ")" ]
[ 0, 0, 0, 2, 2, 2, 0, 0 ]
NCT01941316
23:38:chronic_disease,42:63:chronic_disease,,,,,122:135:chronic_disease,137:156:chronic_disease,176:199:chronic_disease,221:244:chronic_disease,246:265:chronic_disease,270:290:treatment,309:317:chronic_disease
Must not have had any unstable angina or myocardial infarction within 4 months prior to enrollment, NYHA Class III or IV heart failure, uncontrolled angina, history of severe coronary artery disease, severe uncontrolled ventricular arrhythmias, sick sinus syndrome, or electrocardiographic evidence of acute ischemia or Grade 3 conduction system abnormalities unless subject has a pacemaker
3
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NCT01653093
1:44:chronic_disease
Acute or chronic severe renal insufficiency
3
[ "Acute", "or", "chronic", "severe", "renal", "insufficiency" ]
[ 2, 2, 2, 2, 2, 2 ]
NCT03016351
1:21:chronic_disease
rheumatoid arthritis
3
[ "rheumatoid", "arthritis" ]
[ 2, 2 ]
NCT01433965
,,30:45:treatment
Between 6 months to 8 months post transplant
3
[ "Between", "6", "months", "to", "8", "months", "post", "transplant" ]
[ 0, 0, 0, 0, 0, 0, 1, 1 ]
NCT03011567
1:34:chronic_disease
Preeclampsia with severe features
3
[ "Preeclampsia", "with", "severe", "features" ]
[ 2, 2, 2, 2 ]
NCT02091141
4:22:treatment
No previous treatment with the specific assigned study drug or any other drug sharing the same target
3
[ "No", "previous", "treatment", "with", "the", "specific", "assigned", "study", "drug", "or", "any", "other", "drug", "sharing", "the", "same", "target" ]
[ 0, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02819440
12:24:chronic_disease
History of hearing loss
3
[ "History", "of", "hearing", "loss" ]
[ 0, 0, 2, 2 ]
NCT02281409
16:43:treatment,
Any history of systemic anticancer therapy (standard or experimental) completed within 30 days prior to dosing
3
[ "Any", "history", "of", "systemic", "anticancer", "therapy", "(", "standard", "or", "experimental", ")", "completed", "within", "30", "days", "prior", "to", "dosing" ]
[ 0, 0, 0, 1, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT00919503
15:38:chronic_disease,,,,,,,
Patients with impaired renal function as evidenced by creatinine-clearance < 50% for age, weight, height or serum creatinine > 2 x upper normal limit or dialysis-dependent
3
[ "Patients", "with", "impaired", "renal", "function", "as", "evidenced", "by", "creatinine-clearance", "<", "50", "%", "for", "age", ",", "weight", ",", "height", "or", "serum", "creatinine", ">", "2", "x", "upper", "normal", "limit", "or", "dialysis-dependent" ]
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NCT02481713
8:34:chronic_disease
severe auditory/visual impairment
3
[ "severe", "auditory/visual", "impairment" ]
[ 0, 2, 2 ]
NCT01976585
1:7:treatment,28:43:cancer,47:72:cancer,,,,135:161:cancer,166:183:cancer
Biopsy-confirmed low-grade B-cell lymphoma or cutaneous T cell lymphoma; specifically, follicular grade 1, 2, or 3A, marginal zone or small lymphocytic lymphoma, or mycosis fungoides of any initial stage
3
[ "Biopsy-confirmed", "low-grade", "B-cell", "lymphoma", "or", "cutaneous", "T", "cell", "lymphoma", ";", "specifically", ",", "follicular", "grade", "1", ",", "2", ",", "or", "3A", ",", "marginal", "zone", "or", "small", "lymphocytic", "lymphoma", ",", "or", "mycosis", "fungoides", "of", "any", "initial", "stage" ]
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NCT02309892
12:42:treatment,44:56:treatment,60:75:treatment
Concurrent chronic systemic immunotherapy, chemotherapy or hormone therapy
3
[ "Concurrent", "chronic", "systemic", "immunotherapy", ",", "chemotherapy", "or", "hormone", "therapy" ]
[ 0, 1, 1, 1, 0, 1, 0, 1, 1 ]
NCT02418195
1:21:chronic_disease
Autoimmune hepatitis
3
[ "Autoimmune", "hepatitis" ]
[ 2, 2 ]
NCT01869114
25:78:treatment,113:117:chronic_disease,133:150:treatment
Patients may have had a prior stem cell transplant (autologous or allogeneic), however they may not have active GvHD, nor be on any immunosuppression
3
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NCT03006770
1:17:treatment,
minor amputation less than 2 weeks prior to screening
3
[ "minor", "amputation", "less", "than", "2", "weeks", "prior", "to", "screening" ]
[ 1, 1, 0, 0, 0, 0, 0, 0, 0 ]
NCT02903446
14:28:chronic_disease
Uncontrolled hypothyroidism
3
[ "Uncontrolled", "hypothyroidism" ]
[ 0, 2 ]
NCT00840047
80:98:chronic_disease
All participants under the care of St. Jude physicians with known or suspected neoplastic disease
3
[ "All", "participants", "under", "the", "care", "of", "St.", "Jude", "physicians", "with", "known", "or", "suspected", "neoplastic", "disease" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 2, 2 ]
NCT02564744
22:67:chronic_disease
Participants who are Hepatitis B surface antigen positive (HBsAg+) (must be PCR negative) who are taking antivirals, are allowed to enroll
3
[ "Participants", "who", "are", "Hepatitis", "B", "surface", "antigen", "positive", "(", "HBsAg+", ")", "(", "must", "be", "PCR", "negative", ")", "who", "are", "taking", "antivirals", ",", "are", "allowed", "to", "enroll" ]
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NCT03121352
28:59:treatment,
Patients who have received monoclonal anti-cancer antibody within 4 weeks of first dose of study drugs
3
[ "Patients", "who", "have", "received", "monoclonal", "anti-cancer", "antibody", "within", "4", "weeks", "of", "first", "dose", "of", "study", "drugs" ]
[ 0, 0, 0, 0, 1, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02249039
1:43:chronic_disease
Major Chromosomal anomaly (Trisomy 13, 18)
3
[ "Major", "Chromosomal", "anomaly", "(", "Trisomy", "13", ",", "18", ")" ]
[ 2, 2, 2, 2, 2, 2, 0, 0, 0 ]
NCT02512497
,113:123:treatment
Patients taking drugs leading to significant QT prolongation where the interaction is too great to proceed with romidepsin
3
[ "Patients", "taking", "drugs", "leading", "to", "significant", "QT", "prolongation", "where", "the", "interaction", "is", "too", "great", "to", "proceed", "with", "romidepsin" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1 ]
NCT02479230
,,75:91:treatment
International normalized ratio (INR) < 1.5, except for subjects receiving warfarin therapy
3
[ "International", "normalized", "ratio", "(", "INR", ")", "<", "1.5", ",", "except", "for", "subjects", "receiving", "warfarin", "therapy" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 1 ]
NCT02360579
25:31:chronic_disease,49:56:chronic_disease,,126:129:treatment,131:147:treatment,
At least one resectable lesion (or aggregate of lesions resected) of a minimum 1.5 cm in diameter post-resection to generate TIL; surgical removal with minimal morbidity (defined as any procedure for which expected hospitalization is ≤ 3 days)
3
[ "At", "least", "one", "resectable", "lesion", "(", "or", "aggregate", "of", "lesions", "resected", ")", "of", "a", "minimum", "1.5", "cm", "in", "diameter", "post-resection", "to", "generate", "TIL", ";", "surgical", "removal", "with", "minimal", "morbidity", "(", "defined", "as", "any", "procedure", "for", "which", "expected", "hospitalization", "is", "≤", "3", "days", ")" ]
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NCT00881660
1:17:chronic_disease
Fetal aneuploidy, known structural genomic variants, other major fetal anomalies, or known syndromic mutation
3
[ "Fetal", "aneuploidy", ",", "known", "structural", "genomic", "variants", ",", "other", "major", "fetal", "anomalies", ",", "or", "known", "syndromic", "mutation" ]
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NCT01624090
,,67:81:treatment,83:87:treatment,92:102:treatment
Cardiac Function: Left ventricular ejection fraction (EF) >40% by Echocardiogram, MUGA, or cardiac MR
3
[ "Cardiac", "Function", ":", "Left", "ventricular", "ejection", "fraction", "(", "EF", ")", ">", "40", "%", "by", "Echocardiogram", ",", "MUGA", ",", "or", "cardiac", "MR" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 1, 1 ]
NCT02538198
1:16:treatment
Bisphosphonates
3
[ "Bisphosphonates" ]
[ 1 ]
NCT02346201
5:50:chronic_disease,111:122:chronic_disease,,,163:188:chronic_disease,201:211:treatment,,,
Any cardiovascular or cerebrovascular abnormality deemed to be clinically significant by the study physician, tachycardia (heart rate > 100 beats per minute), or uncontrolled hypertension (defined as medication non-compliance or past 3 months with a diastolic reading > 105 mm Hg), at the time of screening
3
[ "Any", "cardiovascular", "or", "cerebrovascular", "abnormality", "deemed", "to", "be", "clinically", "significant", "by", "the", "study", "physician", ",", "tachycardia", "(", "heart", "rate", ">", "100", "beats", "per", "minute", ")", ",", "or", "uncontrolled", "hypertension", "(", "defined", "as", "medication", "non-compliance", "or", "past", "3", "months", "with", "a", "diastolic", "reading", ">", "105", "mm", "Hg", ")", ",", "at", "the", "time", "of", "screening" ]
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NCT02371720
12:23:treatment,
Prescribed Hydroxyurea for at least the 6 months prior to study entry
3
[ "Prescribed", "Hydroxyurea", "for", "at", "least", "the", "6", "months", "prior", "to", "study", "entry" ]
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NCT02835729
28:46:treatment,51:54:cancer,77:88:treatment,92:105:treatment
Patients who have received prior chemotherapy for AML with the exception of hydroxyurea or leukapheresis for leukocytosis
3
[ "Patients", "who", "have", "received", "prior", "chemotherapy", "for", "AML", "with", "the", "exception", "of", "hydroxyurea", "or", "leukapheresis", "for", "leukocytosis" ]
[ 0, 0, 0, 0, 1, 1, 0, 3, 0, 0, 0, 0, 1, 0, 1, 0, 0 ]
NCT02600897
6:17:chronic_disease,19:24:chronic_disease,29:45:chronic_disease
Poor hematologic, renal, or hepatic function
3
[ "Poor", "hematologic", ",", "renal", ",", "or", "hepatic", "function" ]
[ 0, 2, 0, 2, 0, 0, 2, 2 ]
NCT01622868
,,42:53:treatment,,
Hemoglobin >= 8.0 g/dL (note: the use of transfusion or other intervention to achieve hemoglobin [Hgb] >= 8.0 g/dL is acceptable) (within 21 days prior to study entry)
3
[ "Hemoglobin", ">", "=", "8.0", "g/dL", "(", "note", ":", "the", "use", "of", "transfusion", "or", "other", "intervention", "to", "achieve", "hemoglobin", "[", "Hgb", "]", ">", "=", "8.0", "g/dL", "is", "acceptable", ")", "(", "within", "21", "days", "prior", "to", "study", "entry", ")" ]
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NCT02355002
41:50:treatment,58:71:chronic_disease,75:84:chronic_disease
Psychopathology not appropriate for the treatment (e.g., manic episode or psychosis)
3
[ "Psychopathology", "not", "appropriate", "for", "the", "treatment", "(", "e.g.", ",", "manic", "episode", "or", "psychosis", ")" ]
[ 0, 0, 0, 0, 0, 1, 0, 0, 0, 2, 2, 0, 2, 0 ]
NCT02741180
15:31:chronic_disease
No history of heart arrhythmia
3
[ "No", "history", "of", "heart", "arrhythmia" ]
[ 0, 0, 0, 2, 2 ]
NCT01505062
22:59:allergy_name
Any known allergy to any component of the delivery vehicle
3
[ "Any", "known", "allergy", "to", "any", "component", "of", "the", "delivery", "vehicle" ]
[ 0, 0, 0, 0, 4, 4, 4, 4, 4, 4 ]
NCT02048722
12:31:treatment,33:45:treatment,47:54:treatment,56:69:treatment,71:87:treatment,92:110:treatment,140:151:treatment
Concurrent anti-cancer therapy (chemotherapy, surgery, immunotherapy, biologic therapy, or tumor embolization) other than study treatment (regorafenib)
3
[ "Concurrent", "anti-cancer", "therapy", "(", "chemotherapy", ",", "surgery", ",", "immunotherapy", ",", "biologic", "therapy", ",", "or", "tumor", "embolization", ")", "other", "than", "study", "treatment", "(", "regorafenib", ")" ]
[ 0, 1, 1, 0, 1, 0, 1, 0, 1, 0, 1, 1, 0, 0, 1, 1, 0, 0, 0, 0, 0, 0, 1, 0 ]
NCT02587962
78:102:chronic_disease,104:116:chronic_disease,118:142:chronic_disease,144:162:chronic_disease,164:182:chronic_disease,186:207:chronic_disease,212:231:chronic_disease
Uncontrolled intercurrent illness including, but not limited to, symptomatic congestive heart failure, hypertension, unstable angina pectoris, cardiac arrhythmia, autoimmune disease or inflammatory diseases, or psychiatric illness/social situations that would limit compliance with study requirements
3
[ "Uncontrolled", "intercurrent", "illness", "including", ",", "but", "not", "limited", "to", ",", "symptomatic", "congestive", "heart", "failure", ",", "hypertension", ",", "unstable", "angina", "pectoris", ",", "cardiac", "arrhythmia", ",", "autoimmune", "disease", "or", "inflammatory", "diseases", ",", "or", "psychiatric", "illness/social", "situations", "that", "would", "limit", "compliance", "with", "study", "requirements" ]
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NCT00715611
53:74:treatment
consideration should be given to drain the effusion prior to chemotherapy administration
3
[ "consideration", "should", "be", "given", "to", "drain", "the", "effusion", "prior", "to", "chemotherapy", "administration" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 1, 1, 1, 0 ]
NCT03007745
1:20:chronic_disease,29:35:chronic_disease,62:76:chronic_disease
central sleep apnea (50% of apneas on diagnostic testing are central apneas)
3
[ "central", "sleep", "apnea", "(", "50", "%", "of", "apneas", "on", "diagnostic", "testing", "are", "central", "apneas", ")" ]
[ 2, 2, 2, 0, 0, 0, 0, 2, 0, 0, 0, 0, 0, 0, 0 ]
NCT02796391
1:14:treatment
Phenobarbital
3
[ "Phenobarbital" ]
[ 1 ]
NCT02541903
44:72:chronic_disease
History or presence of clinically relevant cardiovascular abnormalities
3
[ "History", "or", "presence", "of", "clinically", "relevant", "cardiovascular", "abnormalities" ]
[ 0, 0, 0, 0, 0, 0, 2, 2 ]
NCT02350764
19:33:cancer
All patients with adenocarcinoma histology must be tested for EGFR and ALK status
3
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NCT01754298
14:37:chronic_disease
Diagnosis of metabolic bone disorder
3
[ "Diagnosis", "of", "metabolic", "bone", "disorder" ]
[ 0, 0, 2, 2, 2 ]
NCT02354703
10:34:chronic_disease
Complete left bundle branch block
3
[ "Complete", "left", "bundle", "branch", "block" ]
[ 0, 2, 2, 2, 2 ]
NCT01920737
45:56:treatment
Active serious infections not controlled by antibiotics
3
[ "Active", "serious", "infections", "not", "controlled", "by", "antibiotics" ]
[ 0, 0, 0, 0, 0, 0, 1 ]
NCT02322203
21:47:treatment,78:85:treatment,87:95:treatment,100:122:treatment
Subjects taking any lipid modification therapy, including but not limited to statins, fibrates and bile acid sequestrants
3
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NCT02500602
17:41:treatment,30:41:treatment,,124:133:treatment
Subjects taking psychotropic medications will be required to be maintained on a stable dose for at least four weeks before treatment initiation. This is because initiation or change of medications during the course of the trial may interfere with interpretation of results
3
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NCT01595529
67:97:treatment
Planned enrollment during this study coincides with enrollment in another therapeutic drug study
3
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NCT02566304
1:8:cancer,
Myeloma with < 5% plasma cells in the marrow
3
[ "Myeloma", "with", "<", "5", "%", "plasma", "cells", "in", "the", "marrow" ]
[ 3, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02983240
1:14:chronic_disease
Fetal anomaly incompatible with life
3
[ "Fetal", "anomaly", "incompatible", "with", "life" ]
[ 2, 2, 0, 0, 0 ]
NCT00632853
54:72:treatment,89:100:treatment,127:138:treatment,142:151:treatment,156:165:treatment
Patients may have received one and only one cycle of chemotherapy prior to enrolling on CALGB 30610, which must have included carboplatin or cisplatin and etoposide
3
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NCT03068130
107:125:treatment
Patients who have an ongoing SAE from a clinical study that is assessed by the investigator as related to bardoxolone methyl
3
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NCT02343042
33:58:treatment
Patients must not have received prior daratumumab therapy (Cohort 5.3 ONLY - dose expansion at RP2D)
3
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NCT01626079
47:69:allergy_name
Known hypersensitivity or contraindication to procedural medications which cannot be adequately managed medically
3
[ "Known", "hypersensitivity", "or", "contraindication", "to", "procedural", "medications", "which", "can", "not", "be", "adequately", "managed", "medically" ]
[ 0, 0, 0, 0, 0, 4, 4, 0, 0, 0, 0, 0, 0, 0 ]
NCT02101034
74:96:treatment
Appropriate studies will be undertaken in patients receiving combination antiretroviral therapy when indicated
3
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[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 1, 0, 0 ]
NCT02624258
,,69:79:treatment
A urine pregnancy test will be performed within 48 hours before the RNA CART19 infusion
3
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NCT02656706
52:71:allergy_name
History of severe hypersensitivity reaction to any monoclonal antibody
3
[ "History", "of", "severe", "hypersensitivity", "reaction", "to", "any", "monoclonal", "antibody" ]
[ 0, 0, 0, 0, 0, 0, 0, 4, 4 ]
NCT02331095
1:13:treatment,
Thrombolysis within 6 weeks prior to enrollment
3
[ "Thrombolysis", "within", "6", "weeks", "prior", "to", "enrollment" ]
[ 1, 0, 0, 0, 0, 0, 0 ]
NCT02393794
34:50:cancer
Subjects with previously treated brain metastasis who are free of central nervous system (CNS) symptoms
3
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NCT02531880
86:94:chronic_disease,86:93:chronic_disease,,222:244:treatment,,
Drug resistant epilepsy participants will be defined as having clinically documented seizures with consistent EEG evidence as defined by the 1981 International Classification of Epileptic Seizures, refractory to standard anti-seizure treatment for at least one year prior to enrolling in this study and with an average of at least one seizure per month
3
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NCT00969111
21:27:cancer,40:68:cancer,
Prior or concurrent cancer, other than non-melanomatous skin cancer, unless disease free for at least 5 years
3
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NCT02710240
28:34:allergy_name
Subjects with a history of iodide allergies
3
[ "Subjects", "with", "a", "history", "of", "iodide", "allergies" ]
[ 0, 0, 0, 0, 0, 4, 0 ]
NCT03170453
10:57:chronic_disease
Comorbid attention deficit hyperactivity disorder (ADHD) that is untreated
3
[ "Comorbid", "attention", "deficit", "hyperactivity", "disorder", "(", "ADHD", ")", "that", "is", "untreated" ]
[ 0, 2, 2, 2, 2, 2, 0, 0, 0, 0, 0 ]
NCT01581580
8:21:chronic_disease
active heart disease needing immediate intervention
3
[ "active", "heart", "disease", "needing", "immediate", "intervention" ]
[ 0, 2, 2, 0, 0, 0 ]
NCT01989585
47:63:chronic_disease,79:102:treatment,126:136:treatment,153:164:treatment,166:175:treatment,177:186:treatment,188:196:treatment,208:222:treatment,224:229:treatment,234:252:treatment,328:355:treatment,365:372:treatment,417:445:treatment,447:454:treatment,,611:626:treatment,631:641:chronic_disease,,,,,829:859:treatment
Due to the expected dose-limiting toxicity of thrombocytopenia, the following concomitant medications are not allowed during navitoclax administration: clopidogrel, ibuprofen, tirofiban, warfarin, and other anticoagulants, drugs, or herbal supplements that affect platelet function are excluded, with the exception of low-dose anticoagulation medications (such as heparin) that are used to maintain the patency of a central intravenous catheter; aspirin will not be allowed within 7 days prior to the first dose of navitoclax or during navitoclax administration; however, subjects who have previously received aspirin therapy for thrombosis prevention may resume a low dose (i.e., maximum 100 mg QD) of aspirin if platelet counts are stable (>= 50,000/mm^3) through 6 weeks of navitoclax administration; all decisions regarding treatment with aspirin therapy will be determined by the investigator in conjunction with the medical monitor
3
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NCT01970176
22:35:chronic_disease,,,,,
Patients with severe liver disease (AST > 3x normal, alkaline phosphatase or bilirubin > 2x normal)
3
[ "Patients", "with", "severe", "liver", "disease", "(", "AST", ">", "3x", "normal", ",", "alkaline", "phosphatase", "or", "bilirubin", ">", "2x", "normal", ")" ]
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NCT02521103
79:101:treatment
Patient is a candidate for revision of all femoral and tibial components of a total knee replacement
3
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NCT02353728
1:29:chronic_disease
Cytogenetic clonal evolution
3
[ "Cytogenetic", "clonal", "evolution" ]
[ 2, 2, 2 ]
NCT02140554
13:16:chronic_disease
Have severe SCD
3
[ "Have", "severe", "SCD" ]
[ 0, 0, 2 ]
NCT01990209
11:31:treatment,,,107:116:treatment,132:141:treatment
Use of an investigational drug ≤21 days or 5 half-lives (whichever is shorter) prior to the first dose of orteronel, or concurrent treatment
3
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NCT01461837
1:4:chronic_disease
SCD patients who have an unaffected HLA matched family donor willing to proceed to donation
3
[ "SCD", "patients", "who", "have", "an", "unaffected", "HLA", "matched", "family", "donor", "willing", "to", "proceed", "to", "donation" ]
[ 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02304458
54:71:chronic_disease
Parts A & C: patients must have either measurable or evaluable disease
3
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NCT03018704
1:23:treatment
bilateral oophorectomy
3
[ "bilateral", "oophorectomy" ]
[ 1, 1 ]
NCT00977977
28:39:chronic_disease,114:123:treatment,186:206:chronic_disease
Patients with a history of arrhythmias will be evaluated by a cardiology consultant regarding recommendations as Rituximab has been reported to exacerbate arrhythmias (in patients with rheumatoid arthritis)
3
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NCT02566304
1:7:chronic_disease,9:18:cancer,23:30:cancer,,137:144:treatment,149:163:treatment,167:186:treatment,209:218:treatment
RAEB-1, RCMD+/-RS, or MDS NOS with stable disease for 6 months (as documented by serial bone marrow examinations) in the absence of any therapy but growth factors or transfusion support. Patients who require treatment to control their disease must show chemo-responsiveness
3
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NCT01096368
64:87:cancer,111:130:cancer,134:165:cancer
Patients must be newly diagnosed with histologically confirmed intracranial ependymoma; patients with classic ependymoma (WHO II) or anaplastic ependymoma (WHO III) are eligible, as are various subtypes described as clear cell, papillary, cellular or a combination of the above
3
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NCT03070535
1:26:chronic_disease
Mild cognitive impairment with no functional deficits is ok
3
[ "Mild", "cognitive", "impairment", "with", "no", "functional", "deficits", "is", "ok" ]
[ 2, 2, 2, 0, 0, 0, 0, 0, 0 ]
NCT01896999
,48:58:treatment,,,
continuing for 5 months after the last dose of study drug (for female patients) and for 7 months after the last dose of study drug (for male patients who are sexually active with WOCBP)
3
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NCT02379520
30:46:treatment
patient is unable to receive standard therapy
3
[ "patient", "is", "unable", "to", "receive", "standard", "therapy" ]
[ 0, 0, 0, 0, 0, 1, 1 ]
NCT02497300
1:22:chronic_disease,
myocardial infarction within the past 6 months
3
[ "myocardial", "infarction", "within", "the", "past", "6", "months" ]
[ 2, 2, 0, 0, 0, 0, 0 ]
NCT03018704
34:37:allergy_name
a history of hypersensitivity to TOP
3
[ "a", "history", "of", "hypersensitivity", "to", "TOP" ]
[ 0, 0, 0, 0, 0, 4 ]
NCT02890979
34:52:chronic_disease
Subjects with known or suspected esophageal varices
3
[ "Subjects", "with", "known", "or", "suspected", "esophageal", "varices" ]
[ 0, 0, 0, 0, 0, 2, 2 ]