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NCT02553460
|
29:63:cancer,67:98:cancer,,157:179:cancer
|
Patient has newly diagnosed acute lymphoblastic leukemia (ALL) or acute undifferentiated leukemia with ≥25% blasts in the bone marrow (M3), with or without extramedullary disease
| 3
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NCT02453373
|
1:24:chronic_disease
|
Ventricular tachycardia
| 3
|
[
"Ventricular",
"tachycardia"
] |
[
2,
2
] |
NCT02359864
|
19:44:treatment
|
Patient is taking anti-epileptic medication
| 3
|
[
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"medication"
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NCT02495168
|
,23:33:treatment
|
for 30 days after the study drug discontinuation
| 3
|
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0,
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NCT02402660
|
11:18:chronic_disease
|
recurring uveitis
| 3
|
[
"recurring",
"uveitis"
] |
[
0,
2
] |
NCT02075671
|
8:28:treatment,
|
Use of systemic antibiotics within 1 month prior to Visit 1
| 3
|
[
"Use",
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"antibiotics",
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"1",
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NCT02075671
|
8:25:treatment,
|
Use of topical retinoids (on the face) within 1 month prior to Visit 1
| 3
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NCT02474927
|
1:11:chronic_disease
|
Leukopenia
| 3
|
[
"Leukopenia"
] |
[
2
] |
NCT01827384
|
5:18:treatment,20:32:treatment,37:50:treatment,,,102:114:treatment,118:129:treatment
|
Any prior therapy, radiotherapy, or major surgery must have been completed >= 3 weeks (> 6 weeks for nitrosoureas or mitomycin C) or 5 half-lives of the agent (whichever is shorter) prior to enrollment on protocol
| 3
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NCT03070535
|
14:28:chronic_disease,32:52:chronic_disease,63:69:treatment,71:87:treatment,89:108:treatment,127:133:treatment
|
Diagnosis of hyperlipidemia or hypertriglyceridemia requiring statin, bile acid resins, fibrate medications, and/or high dose niacin
| 3
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NCT01858168
|
58:64:treatment,66:83:treatment,85:106:treatment,108:127:treatment
|
Concurrent use of the following classes of inhibitors of CYP3A4: azole antifungals, macrolide antibiotics, protease inhibitors
| 3
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NCT02143726
|
25:38:chronic_disease
|
Child Pugh Class B or C liver disease
| 3
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NCT02481310
|
52:77:chronic_disease,89:114:chronic_disease,137:148:chronic_disease,162:186:chronic_disease,188:203:chronic_disease,208:229:chronic_disease,
|
Patients who have evidence of current uncontrolled cardiovascular conditions, including uncontrolled hypertension, uncontrolled cardiac arrhythmias, symptomatic congestive heart failure, unstable angina, or myocardial infarction within the past 6 months
| 3
|
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NCT01835626
|
157:160:cancer
|
All lesions that the investigator proposes to follow as target lesions during the course of the study must have previously been histologically confirmed as BCC
| 3
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NCT02053792
|
42:62:allergy_name
|
subjects who have previously completed a CSL-sponsored rIX-FP study
| 3
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NCT02503722
|
16:25:treatment
|
Placement of a pacemaker for control of rhythm
| 3
|
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NCT02167009
|
15:32:treatment
|
Refractory to medical treatment
| 3
|
[
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0,
0,
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NCT03051516
|
18:30:chronic_disease,39:56:cancer,50:56:cancer,58:66:cancer,68:75:cancer,77:83:cancer,85:91:cancer,96:107:cancer,113:133:cancer
|
Prior history of invasive HPV-related anogenital cancer (cervical, vaginal, vulvar, penile, or anal cancer), or oropharyngeal cancer (base of tongue, tonsil); prior cancer at other sites (including most of oral cavity) or larynx are not exclusions
| 3
|
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NCT02633163
|
25:47:treatment
|
Comorbidities requiring corticosteroid therapy
| 3
|
[
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"requiring",
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"therapy"
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[
0,
0,
1,
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NCT02101944
|
1:14:chronic_disease,,
|
Hypercalcemia: serum calcium > 11.5 mg/dL
| 3
|
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NCT02382549
|
41:57:cancer
|
There has been no evident growth of any brain metastasis since the most recent treatment
| 3
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NCT02553642
|
1:8:treatment,12:28:treatment,34:61:treatment,107:125:chronic_disease
|
Inhaled or topical steroids, and adrenal replacement steroid doses are permitted in the absence of active autoimmune disease
| 3
|
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NCT02095678
|
37:40:treatment
|
Patients with contraindications for MRI due to embedded foreign metallic objects
| 3
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NCT01433965
|
23:35:cancer,,,,108:118:cancer,120:155:cancer,160:201:cancer
|
Disease free of other malignancies beside the AML or MDS for ≥ 2 years with exception of currently treated basal cell, squamous cell carcinoma of the skin, or carcinoma in situ of the cervix or breast
| 3
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NCT02493530
|
1:17:treatment
|
Organ transplant recipients
| 3
|
[
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[
1,
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0
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NCT02549937
|
,,,54:65:chronic_disease,,
|
Urine protein > 2+; Patients discovered to have ≥ 1+ proteinuria on dipstick urinalysis at baseline should undergo a 24-hour urine collection and must demonstrate < 1 g of protein in 24-hour urine
| 3
|
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NCT03086473
|
44:65:chronic_disease,78:102:chronic_disease,104:124:chronic_disease,132:152:chronic_disease,164:189:chronic_disease,196:206:treatment
|
Exclusions are major congenital anomalies, major cardiac defects (other than patent ductus arteriosus, patent foramen ovale, small atrial septal defect, and small ventricular septal defect), and intubation in the delivery room
| 3
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NCT02489539
|
1:20:chronic_disease,,
|
Renal insufficiency defined as creatinine > 2.5 mg/dL
| 3
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NCT02699697
|
,,,,,110:118:treatment
|
Pain score of at least 5 on a scale of 0 - 10 within a week of enrollment OR pain score < 5 with >= 60 mg of morphine (or equivalent) per day
| 3
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NCT02826681
|
1:14:chronic_disease,22:45:chronic_disease,49:60:chronic_disease
|
Secondary RLS due to neurological conditions or head trauma
| 3
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NCT03087903
|
45:61:allergy_name
|
Documented hypersensitivity reaction to any product with GSE (see complete list in Appendix 1)
| 3
|
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NCT02516969
|
,,115:129:treatment
|
have a positive pregnancy test (reproductive age should use effective birth control during study if randomized to SBRT treatment arm)
| 3
|
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NCT01169155
|
15:33:chronic_disease
|
Subject has a hearing impairment
| 3
|
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NCT02091141
|
73:76:chronic_disease,91:99:chronic_disease,,,,,,,,,277:289:chronic_disease,351:379:treatment
|
Presence of any of the following conditions, which are risk factors for RVO: Uncontrolled glaucoma with intraocular pressure >21 millimetres of mercury (mm Hg); Serum cholesterol ≥Grade 2; Hypertriglyceridemia ≥Grade 2; Hyperglycemia (fasting) ≥Grade 2; Grade ≥2 uncontrolled hypertension (participants with a history of hypertension controlled with anti-hypertensive medication to Grade </=1 are eligible)
| 3
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"of",
"hypertension",
"controlled",
"with",
"anti-hypertensive",
"medication",
"to",
"Grade",
"<",
"/=1",
"are",
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NCT02332369
|
1:16:chronic_disease
|
Corneal disease
| 3
|
[
"Corneal",
"disease"
] |
[
2,
2
] |
NCT01849146
|
14:34:chronic_disease,77:93:chronic_disease,107:131:chronic_disease,133:157:chronic_disease,159:177:chronic_disease,182:201:chronic_disease
|
uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements, are ineligible
| 3
|
[
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NCT02172651
|
18:30:treatment,34:43:treatment,,98:111:treatment
|
The last dose of chemotherapy or radiation must have been administered at least 4 weeks prior to liver surgery
| 3
|
[
"The",
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NCT02725177
|
14:27:chronic_disease,
|
Severe other organ disease felt to be likely to lead to death within the next six months
| 3
|
[
"Severe",
"other",
"organ",
"disease",
"felt",
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NCT02398773
|
24:37:chronic_disease
|
Patient must NOT be in liver failure as judged by the patient's physician
| 3
|
[
"Patient",
"must",
"NOT",
"be",
"in",
"liver",
"failure",
"as",
"judged",
"by",
"the",
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0,
0,
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0,
2,
2,
0,
0,
0,
0,
0,
0,
0
] |
NCT02226159
|
,40:49:treatment
|
More than one cervical level requiring injection
| 3
|
[
"More",
"than",
"one",
"cervical",
"level",
"requiring",
"injection"
] |
[
0,
0,
0,
0,
0,
0,
1
] |
NCT01950351
|
39:69:cancer,
|
Histologically confirmed diagnosis of adenocarcinoma of the prostate within one year of study entry
| 3
|
[
"Histologically",
"confirmed",
"diagnosis",
"of",
"adenocarcinoma",
"of",
"the",
"prostate",
"within",
"one",
"year",
"of",
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[
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3,
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0,
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0
] |
NCT03162731
|
24:41:treatment,,57:67:treatment,84:108:treatment
|
syndrome that requires systemic steroids (> 10 mg daily prednisone equivalents) or immunosuppressive agents
| 3
|
[
"syndrome",
"that",
"requires",
"systemic",
"steroids",
"(",
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"10",
"mg",
"daily",
"prednisone",
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"or",
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0,
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] |
NCT01787682
|
17:20:chronic_disease
|
No diagnosis of CHF
| 3
|
[
"No",
"diagnosis",
"of",
"CHF"
] |
[
0,
0,
0,
2
] |
NCT02495935
|
1:11:chronic_disease,
|
Strabismus less than 10 prism diopters
| 3
|
[
"Strabismus",
"less",
"than",
"10",
"prism",
"diopters"
] |
[
2,
0,
0,
0,
0,
0
] |
NCT02913430
|
36:56:treatment
|
Washout of 2 weeks is required for aromatase inhibitors
| 3
|
[
"Washout",
"of",
"2",
"weeks",
"is",
"required",
"for",
"aromatase",
"inhibitors"
] |
[
0,
0,
0,
0,
0,
0,
0,
1,
1
] |
NCT01829958
|
14:31:chronic_disease
|
Uncontrolled diabetes mellitus
| 3
|
[
"Uncontrolled",
"diabetes",
"mellitus"
] |
[
0,
2,
2
] |
NCT02237183
|
74:101:treatment,109:115:chronic_disease,116:122:chronic_disease,126:149:cancer,
|
Participants must not be currently receiving or have previously received thiazolidinedione treatment unless sputum atypia or endobronchial dysplasia are documented again after thiazolidinedione treatment and within 12 months of entry
| 3
|
[
"Participants",
"must",
"not",
"be",
"currently",
"receiving",
"or",
"have",
"previously",
"received",
"thiazolidinedione",
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"unless",
"sputum",
"atypia",
"or",
"endobronchial",
"dysplasia",
"are",
"documented",
"again",
"after",
"thiazolidinedione",
"treatment",
"and",
"within",
"12",
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"of",
"entry"
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NCT02357784
|
5:8:chronic_disease
|
has QTc prolongation
| 3
|
[
"has",
"QTc",
"prolongation"
] |
[
0,
2,
0
] |
NCT02451423
|
28:59:treatment
|
Subjects who have received prior intravesical chemotherapy are allowed
| 3
|
[
"Subjects",
"who",
"have",
"received",
"prior",
"intravesical",
"chemotherapy",
"are",
"allowed"
] |
[
0,
0,
0,
0,
1,
1,
1,
0,
0
] |
NCT02213913
|
1:19:treatment
|
Prior pomalidomide exposure
| 3
|
[
"Prior",
"pomalidomide",
"exposure"
] |
[
1,
1,
0
] |
NCT01261728
|
9:29:chronic_disease,,
|
Ongoing cardiac dysrhythmias of NCI CTCAE Version 4.0 grade ≥ 2
| 3
|
[
"Ongoing",
"cardiac",
"dysrhythmias",
"of",
"NCI",
"CTCAE",
"Version",
"4.0",
"grade",
"≥",
"2"
] |
[
0,
2,
2,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT02365467
|
26:44:chronic_disease,46:58:chronic_disease,71:88:treatment
|
Subject has a history of bleeding diathesis, coagulopathy, or refuses blood transfusion
| 3
|
[
"Subject",
"has",
"a",
"history",
"of",
"bleeding",
"diathesis",
",",
"coagulopathy",
",",
"or",
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"blood",
"transfusion"
] |
[
0,
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NCT01184547
|
1:20:chronic_disease
|
Renal insufficiency
| 3
|
[
"Renal",
"insufficiency"
] |
[
2,
2
] |
NCT02217709
|
1:27:treatment,,
|
Post-radical prostatectomy: Any PSA >= 0.4 ng/ml
| 3
|
[
"Post-radical",
"prostatectomy",
":",
"Any",
"PSA",
">",
"=",
"0.4",
"ng/ml"
] |
[
1,
1,
0,
0,
0,
0,
0,
0,
0
] |
NCT00670358
|
4:25:chronic_disease,
|
No myocardial infarction within the past 6 months
| 3
|
[
"No",
"myocardial",
"infarction",
"within",
"the",
"past",
"6",
"months"
] |
[
0,
2,
2,
0,
0,
0,
0,
0
] |
NCT01925131
|
55:71:chronic_disease
|
Patients must not have a history of chronic or active hepatitis B or C infection
| 3
|
[
"Patients",
"must",
"not",
"have",
"a",
"history",
"of",
"chronic",
"or",
"active",
"hepatitis",
"B",
"or",
"C",
"infection"
] |
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
2,
2,
2,
2,
0
] |
NCT02965638
|
1:20:chronic_disease,84:96:chronic_disease,,132:144:chronic_disease,175:199:chronic_disease,201:224:chronic_disease,226:239:chronic_disease,257:266:treatment,269:293:chronic_disease,302:308:chronic_disease,,,349:370:chronic_disease,,,414:435:chronic_disease,490:524:chronic_disease
|
Maternal conditions that may alter fetal hemodynamic, including moderate to severe hypertension requiring medication in pregnancy, preeclampsia, major or unrepaired maternal congenital heart disease, obstructive sleep apnea, severe asthma (requiring daily treatment), restrictive lung disease, severe anemia (hemoglobin less than 8 g/dL), maternal chronic renal disease (creatinine greater than 1.2 mg/dL), known placental abnormality (complete placenta previa, accrete, or percreta), and antiphospholipid antibody syndrome
| 3
|
[
"Maternal",
"conditions",
"that",
"may",
"alter",
"fetal",
"hemodynamic",
",",
"including",
"moderate",
"to",
"severe",
"hypertension",
"requiring",
"medication",
"in",
"pregnancy",
",",
"preeclampsia",
",",
"major",
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"unrepaired",
"maternal",
"congenital",
"heart",
"disease",
",",
"obstructive",
"sleep",
"apnea",
",",
"severe",
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",",
"restrictive",
"lung",
"disease",
",",
"severe",
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")",
",",
"maternal",
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"creatinine",
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",",
"known",
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",",
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NCT02481765
|
40:48:chronic_disease,50:60:chronic_disease,62:67:chronic_disease,69:83:chronic_disease,85:90:chronic_disease,92:110:chronic_disease,112:121:chronic_disease,123:142:chronic_disease,146:152:cancer
|
Previous or current medical history of epilepsy, neurologic, heart, endocrinologic, renal, chronic infectious, metabolic, psychiatric disease or cancer
| 3
|
[
"Previous",
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"current",
"medical",
"history",
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",",
"neurologic",
",",
"heart",
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"endocrinologic",
",",
"renal",
",",
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"psychiatric",
"disease",
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"cancer"
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0,
2,
2,
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3
] |
NCT01421095
|
28:35:cancer
|
Estrogen receptor positive cancers
| 3
|
[
"Estrogen",
"receptor",
"positive",
"cancers"
] |
[
0,
0,
0,
3
] |
NCT02565199
|
1:29:chronic_disease,,
|
Impaired cognitive abilities (score lesser than 75th percentile on the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS))
| 3
|
[
"Impaired",
"cognitive",
"abilities",
"(",
"score",
"lesser",
"than",
"75th",
"percentile",
"on",
"the",
"Repeatable",
"Battery",
"for",
"the",
"Assessment",
"of",
"Neuropsychological",
"Status",
"(",
"RBANS",
")",
")"
] |
[
2,
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2,
0,
0,
0,
0,
0,
0,
0,
0,
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0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT02195232
|
35:68:treatment,
|
Receiving or scheduled to receive first or second line chemotherapy (within 30 days of registration)
| 3
|
[
"Receiving",
"or",
"scheduled",
"to",
"receive",
"first",
"or",
"second",
"line",
"chemotherapy",
"(",
"within",
"30",
"days",
"of",
"registration",
")"
] |
[
0,
0,
0,
0,
0,
1,
1,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0
] |
NCT02873598
|
,,96:109:treatment,
|
A negative urine or serum pregnancy test must be obtained within 14 days prior to the start of study therapy in all women of child-bearing potential
| 3
|
[
"A",
"negative",
"urine",
"or",
"serum",
"pregnancy",
"test",
"must",
"be",
"obtained",
"within",
"14",
"days",
"prior",
"to",
"the",
"start",
"of",
"study",
"therapy",
"in",
"all",
"women",
"of",
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"potential"
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[
0,
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1,
0,
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0,
0,
0,
0
] |
NCT02207439
|
77:101:chronic_disease,103:127:chronic_disease,132:151:chronic_disease
|
Uncontrolled intercurrent illness including, but not limited to symptomatic congestive heart failure, unstable angina pectoris, or psychiatric illness/social situations that would limit compliance with study requirements
| 3
|
[
"Uncontrolled",
"intercurrent",
"illness",
"including",
",",
"but",
"not",
"limited",
"to",
"symptomatic",
"congestive",
"heart",
"failure",
",",
"unstable",
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"or",
"psychiatric",
"illness/social",
"situations",
"that",
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"with",
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0,
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0,
0,
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2,
2,
2,
0,
0,
2,
2,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT02544880
|
29:53:cancer,55:72:cancer,77:95:cancer
|
Recurrent or second primary HNSCC of the nasopharynx, paranasal sinuses, or cervical esophagus
| 3
|
[
"Recurrent",
"or",
"second",
"primary",
"HNSCC",
"of",
"the",
"nasopharynx",
",",
"paranasal",
"sinuses",
",",
"or",
"cervical",
"esophagus"
] |
[
0,
0,
0,
0,
3,
3,
3,
3,
0,
3,
3,
0,
0,
3,
3
] |
NCT01620216
|
1:12:treatment,71:81:treatment,,145:157:chronic_disease
|
hydroxyurea is allowed prior to enrollment and after the start of the study drug for the control of peripheral leukemic blasts in subjects with leukocytosis per physician discretion
| 3
|
[
"hydroxyurea",
"is",
"allowed",
"prior",
"to",
"enrollment",
"and",
"after",
"the",
"start",
"of",
"the",
"study",
"drug",
"for",
"the",
"control",
"of",
"peripheral",
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"blasts",
"in",
"subjects",
"with",
"leukocytosis",
"per",
"physician",
"discretion"
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[
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0,
0,
0,
0,
0,
0,
0,
0,
2,
0,
0,
0
] |
NCT00909909
|
,25:45:cancer
|
No more than 9 positive axillary lymph nodes
| 3
|
[
"No",
"more",
"than",
"9",
"positive",
"axillary",
"lymph",
"nodes"
] |
[
0,
0,
0,
0,
0,
3,
3,
3
] |
NCT03179397
|
1:17:chronic_disease
|
Systemic disease that could increase the operative risk or confound the outcome
| 3
|
[
"Systemic",
"disease",
"that",
"could",
"increase",
"the",
"operative",
"risk",
"or",
"confound",
"the",
"outcome"
] |
[
2,
2,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT02422641
|
1:13:chronic_disease,17:45:chronic_disease,55:75:chronic_disease,118:124:treatment,140:149:treatment
|
Uncontrolled or progressive systemic disease or other concurrent condition which in the Investigator's opinion makes HD-MTX an undesirable treatment option for the patient or would jeopardize compliance
| 3
|
[
"Uncontrolled",
"or",
"progressive",
"systemic",
"disease",
"or",
"other",
"concurrent",
"condition",
"which",
"in",
"the",
"Investigator",
"'s",
"opinion",
"makes",
"HD-MTX",
"an",
"undesirable",
"treatment",
"option",
"for",
"the",
"patient",
"or",
"would",
"jeopardize",
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] |
[
2,
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1,
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0,
0,
0,
0
] |
NCT03140527
|
14:16:chronic_disease,26:33:treatment,34:50:treatment,126:147:chronic_disease,151:167:chronic_disease,168:193:chronic_disease
|
diagnosis of CF with the F508del/F508del genotype on record, along with clinical findings consistent with CF such as chronic sinopulmonary disease or gastrointestinal/nutritional abnormalities
| 3
|
[
"diagnosis",
"of",
"CF",
"with",
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"genotype",
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",",
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"chronic",
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0,
0,
2,
2,
0,
2,
2
] |
NCT02833792
|
12:18:cancer,,76:81:cancer,85:108:cancer
|
History of cancer within the past 5 years, with the exception of localized basal or squamous cell carcinoma
| 3
|
[
"History",
"of",
"cancer",
"within",
"the",
"past",
"5",
"years",
",",
"with",
"the",
"exception",
"of",
"localized",
"basal",
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"squamous",
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0,
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0,
0,
0,
0,
3,
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3,
3,
3
] |
NCT02670837
|
1:39:chronic_disease
|
Junctional Epidermolysis Bullosa (JEB) with at least one wound
| 3
|
[
"Junctional",
"Epidermolysis",
"Bullosa",
"(",
"JEB",
")",
"with",
"at",
"least",
"one",
"wound"
] |
[
2,
2,
2,
2,
0,
0,
0,
0,
0,
0,
0
] |
NCT02088554
|
16:38:chronic_disease
|
Patient has an anatomical abnormality which would increase surgical risk of morbidity or mortality
| 3
|
[
"Patient",
"has",
"an",
"anatomical",
"abnormality",
"which",
"would",
"increase",
"surgical",
"risk",
"of",
"morbidity",
"or",
"mortality"
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[
0,
0,
0,
2,
2,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT02519322
|
15:24:cancer,26:33:cancer,35:40:cancer,42:47:cancer,52:77:cancer
|
patients with cutaneous, mucosal, acral, ocular or unknown primary melanomas are eligible for enrollment
| 3
|
[
"patients",
"with",
"cutaneous",
",",
"mucosal",
",",
"acral",
",",
"ocular",
"or",
"unknown",
"primary",
"melanomas",
"are",
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3,
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3,
3,
3,
3,
3,
3,
3,
3,
3,
3,
3,
3,
3
] |
NCT03088033
|
1:23:chronic_disease,
|
Advanced heart failure defined as one or more
| 3
|
[
"Advanced",
"heart",
"failure",
"defined",
"as",
"one",
"or",
"more"
] |
[
2,
2,
2,
0,
0,
0,
0,
0
] |
NCT02823665
|
12:24:chronic_disease
|
history of dyslipidemia
| 3
|
[
"history",
"of",
"dyslipidemia"
] |
[
0,
0,
2
] |
NCT02914171
|
18:53:chronic_disease
|
Individuals with preoperative ventricular arrhythmia requiring medical management
| 3
|
[
"Individuals",
"with",
"preoperative",
"ventricular",
"arrhythmia",
"requiring",
"medical",
"management"
] |
[
0,
0,
2,
2,
2,
0,
0,
0
] |
NCT01737502
|
37:52:treatment,54:62:treatment,64:75:treatment,77:119:treatment
|
Unable to discontinue use of potent cytochrome P450, family 3, subfamily A, polypeptide 4 (CYP3A4) inhibitors/inducers
| 3
|
[
"Unable",
"to",
"discontinue",
"use",
"of",
"potent",
"cytochrome",
"P450",
",",
"family",
"3",
",",
"subfamily",
"A",
",",
"polypeptide",
"4",
"(",
"CYP3A4",
")",
"inhibitors/inducers"
] |
[
0,
0,
0,
0,
0,
0,
1,
1,
0,
1,
1,
0,
1,
1,
0,
1,
1,
1,
1,
0,
0
] |
NCT01842399
|
100:115:chronic_disease,128:142:treatment,173:194:chronic_disease,,223:229:chronic_disease,237:246:treatment
|
Unable to perform treadmill testing due to reasons such as orthopedic problems, moderate to severe aortic stenosis as found on echocardiogram at ScreeningVisit, history of myocardial infarction in the last three months or angina (under treatment)
| 3
|
[
"Unable",
"to",
"perform",
"treadmill",
"testing",
"due",
"to",
"reasons",
"such",
"as",
"orthopedic",
"problems",
",",
"moderate",
"to",
"severe",
"aortic",
"stenosis",
"as",
"found",
"on",
"echocardiogram",
"at",
"ScreeningVisit",
",",
"history",
"of",
"myocardial",
"infarction",
"in",
"the",
"last",
"three",
"months",
"or",
"angina",
"(",
"under",
"treatment",
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0,
0,
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0,
0,
0,
0,
0,
2,
0,
0,
1,
0
] |
NCT01662466
|
1:15:chronic_disease
|
Hyperlipidemia
| 3
|
[
"Hyperlipidemia"
] |
[
2
] |
NCT01940757
|
24:37:chronic_disease,,
|
Laboratory evidence of liver disease (alanine aminotransferase [ALT] greater than 1.25-times the upper reference limit)
| 3
|
[
"Laboratory",
"evidence",
"of",
"liver",
"disease",
"(",
"alanine",
"aminotransferase",
"[",
"ALT",
"]",
"greater",
"than",
"1.25-times",
"the",
"upper",
"reference",
"limit",
")"
] |
[
0,
0,
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2,
2,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT02227199
|
32:51:treatment
|
Patients with prior receipt of brentuximab vedotin
| 3
|
[
"Patients",
"with",
"prior",
"receipt",
"of",
"brentuximab",
"vedotin"
] |
[
0,
0,
0,
0,
0,
1,
1
] |
NCT03035773
|
19:44:cancer
|
Diagnosed with in situ or metastatic breast
| 3
|
[
"Diagnosed",
"with",
"in",
"situ",
"or",
"metastatic",
"breast"
] |
[
0,
0,
0,
3,
3,
3,
3
] |
NCT03011801
|
13:46:chronic_disease
|
Presence of cervical or uterine abnormalities
| 3
|
[
"Presence",
"of",
"cervical",
"or",
"uterine",
"abnormalities"
] |
[
0,
0,
2,
2,
2,
2
] |
NCT01600040
|
45:75:treatment,79:99:treatment,104:119:treatment,131:143:treatment
|
Have undergone simple, modified radical, or radical abdominal hysterectomy or vaginal hysterectomy and lymphadenectomy by open or laparoscopic assisted technique
| 3
|
[
"Have",
"undergone",
"simple",
",",
"modified",
"radical",
",",
"or",
"radical",
"abdominal",
"hysterectomy",
"or",
"vaginal",
"hysterectomy",
"and",
"lymphadenectomy",
"by",
"open",
"or",
"laparoscopic",
"assisted",
"technique"
] |
[
0,
0,
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1,
0,
0,
0,
0,
1,
1,
0,
1,
0,
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0,
1,
0,
0
] |
NCT02446886
|
67:69:chronic_disease,96:108:chronic_disease,110:121:chronic_disease,123:132:chronic_disease,134:141:chronic_disease,143:148:chronic_disease,150:163:chronic_disease,165:174:chronic_disease,176:190:chronic_disease,202:227:chronic_disease,230:246:chronic_disease,248:267:chronic_disease,301:310:chronic_disease
|
Subject currently has a significant medical condition (other than MS) including the following: neurological, psychiatric, metabolic, hepatic, renal, hematological, pulmonary, cardiovascular (including uncontrolled hypertension), gastrointestinal, urological disorder, or central nervous system (CNS) infection that would pose a risk to the subject if they were to participate in the study or that might confound the results of the study
| 3
|
[
"Subject",
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"condition",
"(",
"other",
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"including",
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"following",
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"neurological",
",",
"psychiatric",
",",
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",",
"hepatic",
",",
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",",
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",",
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"including",
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0
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NCT02192398
|
17:28:treatment,50:77:treatment,88:107:treatment,114:123:treatment,129:138:treatment,142:169:treatment,176:186:treatment,188:199:treatment,201:210:treatment
|
Subjects are on medications that are ligands for alpha2-adrenergic receptors including antipsychotic drugs (e.g. clozapine) and tricyclic or tetracyclic antidepressants (e.g. imipramine, mirtazapine, mianserin)
| 3
|
[
"Subjects",
"are",
"on",
"medications",
"that",
"are",
"ligands",
"for",
"alpha2-adrenergic",
"receptors",
"including",
"antipsychotic",
"drugs",
"(",
"e.g",
".",
"clozapine",
")",
"and",
"tricyclic",
"or",
"tetracyclic",
"antidepressants",
"(",
"e.g",
".",
"imipramine",
",",
"mirtazapine",
",",
"mianserin",
")"
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[
0,
0,
0,
1,
0,
0,
0,
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1,
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0,
0,
1,
0,
1,
1,
0,
0,
0,
1,
0,
1,
0,
1,
0
] |
NCT02487082
|
1:21:chronic_disease
|
Peptic ulcer disease
| 3
|
[
"Peptic",
"ulcer",
"disease"
] |
[
2,
2,
2
] |
NCT01660607
|
1:26:cancer
|
Myelodysplastic syndromes
| 3
|
[
"Myelodysplastic",
"syndromes"
] |
[
3,
3
] |
NCT00909909
|
81:93:treatment
|
No evidence of suspicious microcalcifications in the breast before the start of radiotherapy
| 3
|
[
"No",
"evidence",
"of",
"suspicious",
"microcalcifications",
"in",
"the",
"breast",
"before",
"the",
"start",
"of",
"radiotherapy"
] |
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1
] |
NCT02479230
|
32:40:treatment,60:69:treatment,73:83:chronic_disease
|
for subjects who are receiving warfarin for prophylaxis or treatment of thrombosis, INR values should be carefully monitored while patients are on study
| 3
|
[
"for",
"subjects",
"who",
"are",
"receiving",
"warfarin",
"for",
"prophylaxis",
"or",
"treatment",
"of",
"thrombosis",
",",
"INR",
"values",
"should",
"be",
"carefully",
"monitored",
"while",
"patients",
"are",
"on",
"study"
] |
[
0,
0,
0,
0,
0,
1,
0,
0,
0,
1,
0,
2,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT02420977
|
,36:51:treatment
|
At least 10 days after most recent prostate biopsy
| 3
|
[
"At",
"least",
"10",
"days",
"after",
"most",
"recent",
"prostate",
"biopsy"
] |
[
0,
0,
0,
0,
0,
0,
0,
1,
1
] |
NCT02987491
|
1:14:chronic_disease,,
|
Hyperglycemia (fasting glucose >126 mg/dl)
| 3
|
[
"Hyperglycemia",
"(",
"fasting",
"glucose",
">",
"126",
"mg/dl",
")"
] |
[
2,
0,
0,
0,
0,
0,
0,
0
] |
NCT02100722
|
11:36:treatment
|
Requiring renal replacement therapy
| 3
|
[
"Requiring",
"renal",
"replacement",
"therapy"
] |
[
0,
1,
1,
1
] |
NCT02347111
|
24:37:allergy_name
|
Contra-indication to a class III AAD
| 3
|
[
"Contra-indication",
"to",
"a",
"class",
"III",
"AAD"
] |
[
0,
0,
0,
4,
4,
4
] |
NCT00985205
|
,,44:52:treatment
|
Deep 2nd and/or 3rd degree burns requiring grafting
| 3
|
[
"Deep",
"2nd",
"and/or",
"3rd",
"degree",
"burns",
"requiring",
"grafting"
] |
[
0,
0,
0,
0,
0,
0,
0,
1
] |
NCT03114319
|
1:40:chronic_disease
|
Insufficient hepatic and renal function
| 3
|
[
"Insufficient",
"hepatic",
"and",
"renal",
"function"
] |
[
2,
2,
2,
2,
2
] |
NCT02391402
|
11:34:treatment,46:54:treatment,,,186:195:treatment,284:300:treatment,319:343:treatment,347:356:treatment,
|
Initiated psychotropic medication, including Prazosin, within 4 weeks or changed dosage within 2 weeks prior to the first assessment, as this would make it difficult to determine which treatment contributed to change in the CABA condition; additionally, started or changed dosage of sleep medication or low dosages of tricyclic antidepressant or trazodone for pain or sleep within 1 week prior to the first assessment
| 3
|
[
"Initiated",
"psychotropic",
"medication",
",",
"including",
"Prazosin",
",",
"within",
"4",
"weeks",
"or",
"changed",
"dosage",
"within",
"2",
"weeks",
"prior",
"to",
"the",
"first",
"assessment",
",",
"as",
"this",
"would",
"make",
"it",
"difficult",
"to",
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"which",
"treatment",
"contributed",
"to",
"change",
"in",
"the",
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";",
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",",
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"or",
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"sleep",
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"1",
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"to",
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0,
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0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT02582827
|
,,,,,183:193:treatment
|
Women of childbearing potential and women < 12 months since onset of menopause must have a negative serum pregnancy test (ß-hCG) within 24 hours prior to the first administration of study drug
| 3
|
[
"Women",
"of",
"childbearing",
"potential",
"and",
"women",
"<",
"12",
"months",
"since",
"onset",
"of",
"menopause",
"must",
"have",
"a",
"negative",
"serum",
"pregnancy",
"test",
"(",
"ß-hCG",
")",
"within",
"24",
"hours",
"prior",
"to",
"the",
"first",
"administration",
"of",
"study",
"drug"
] |
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1
] |
NCT02469389
|
1:21:chronic_disease
|
Cognitive impairment
| 3
|
[
"Cognitive",
"impairment"
] |
[
2,
2
] |
NCT02132598
|
12:28:treatment
|
History of organ transplant
| 3
|
[
"History",
"of",
"organ",
"transplant"
] |
[
0,
0,
1,
1
] |
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