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NCT02496208
|
48:51:treatment,55:117:treatment,142:165:cancer
|
Patients who have been previously treated with MET or vascular endothelial growth factor receptor (VEGFR) inhibitors (except for patients on renal cell cancer [RCC] cohort) are not eligible for the expansion cohorts but can enroll in the phase I portion
| 3
|
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NCT02056873
|
4:14:treatment,53:67:treatment,117:129:treatment
|
If medication trials resulted in discontinuation of TS medications, the subject must be stabilized for 3 months off TS medicines
| 3
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NCT02101736
|
19:22:treatment
|
Central review or MRI required prior to enrollment
| 3
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NCT02769000
|
12:25:chronic_disease
|
History of Hydrocephalus
| 3
|
[
"History",
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[
0,
0,
2
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NCT02236000
|
20:35:treatment
|
ability to swallow oral medication
| 3
|
[
"ability",
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[
0,
0,
0,
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1
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NCT00720785
|
7:45:chronic_disease
|
Acute diffuse infiltrative pulmonary disease
| 3
|
[
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"disease"
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[
0,
2,
2,
2,
2
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NCT01668082
|
18:32:chronic_disease
|
Patients who are claustrophobic or have other contraindications to MRI, such as impanted pacemaker device vascular clips, surgical clips, prosthetic valves, pacemakers, otologic implants
| 3
|
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NCT02266329
|
16:24:treatment,
|
Current use of prazosin at a dose of >2 mg or other alpha-1 antagonist for any purpose
| 3
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NCT02169037
|
21:28:treatment
|
contraindication to Heparin
| 3
|
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"contraindication",
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0,
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NCT02203903
|
10:111:treatment
|
Received prior or anticipated myeloablative or non-myeloablative allogeneic hematopoietic stem cell transplant
| 3
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NCT02548104
|
1:14:treatment
|
Bilateral TKA
| 3
|
[
"Bilateral",
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[
1,
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NCT02195232
|
14:34:chronic_disease,76:92:chronic_disease,106:130:chronic_disease,141:156:chronic_disease,166:176:chronic_disease,181:200:chronic_disease
|
Uncontrolled intercurrent illness including, but not limited to ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
| 3
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NCT02819635
|
14:40:chronic_disease
|
diagnosis of indeterminate colitis (IC)
| 3
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NCT02354547
|
44:62:treatment
|
Patients who are currently receiving other anti-cancer agents
| 3
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NCT01543490
|
11:30:treatment,49:82:treatment,68:82:treatment,
|
Have used topical medications on the eyelids or topical ophthalmic corticosteroid medications or systemic use of a corticosteroid mediation within 14 days prior to dosing and/or plan to use them throughout the duration of the study
| 3
|
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NCT02080221
|
27:38:allergy_name,42:52:allergy_name
|
Prior hypersensitivity to Oxaliplatin or Abraxane ® that in the investigators opinion would put the patient at risk if re-exposed
| 3
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NCT02992899
|
26:63:chronic_disease
|
Do not meet criteria for post traumatic stress disorder (PTSD)
| 3
|
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NCT01415882
|
18:30:treatment,32:44:treatment,53:70:treatment
|
Other concurrent chemotherapy, radiotherapy, or any ancillary therapy considered investigational
| 3
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NCT02004275
|
4:7:treatment,,,
|
No EKG evidence of > grade 2 (> 480 ms) corrected QT (QTc) prolongation
| 3
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NCT02516670
|
26:46:treatment
|
Patient may be receiving bone targeted agents
| 3
|
[
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NCT02587962
|
62:94:cancer,123:133:cancer,152:159:treatment
|
Patients must have histologically or cytologically confirmed cervical squamous cell carcinoma that is locally advanced or metastatic with no available therapy options that are known to provide clinical benefit per institutional standard of care
| 3
|
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NCT02013336
|
,,,22:46:chronic_disease,48:71:chronic_disease,75:102:chronic_disease
|
NYHA Class III or IV congestive heart failure, ventricular arrhythmias or uncontrolled blood pressure
| 3
|
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NCT02332291
|
1:4:allergy_name
|
MRI contraindications
| 3
|
[
"MRI",
"contraindications"
] |
[
4,
0
] |
NCT02593110
|
1:31:treatment
|
Above or below knee amputation
| 3
|
[
"Above",
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"below",
"knee",
"amputation"
] |
[
1,
1,
1,
1,
1
] |
NCT02131597
|
1:25:treatment,,41:57:treatment,61:72:treatment,75:93:treatment,98:123:treatment
|
Prior biologic therapies (=< 1 cycle of prior decitabine or azacitidine), targeted therapies, or single agent chemotherapy is allowed
| 3
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NCT02140255
|
24:27:treatment,,78:83:treatment,,120:123:treatment,125:128:treatment,130:135:treatment
|
Received first dose of ART within 48 hours of birth on a regimen including 2 NRTIs and at least one other agent (e.g., NVP, RAL, LPV/r)
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NCT03112720
|
24:59:treatment
|
Subjects that received prior therapy with SPG block or EBP
| 3
|
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NCT01572480
|
,,44:56:treatment
|
hemoglobin greater than or equal to 8 g/dL(transfusions are permissible)
| 3
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NCT02320292
|
14:34:chronic_disease,77:93:chronic_disease,107:131:chronic_disease,142:157:chronic_disease,180:190:chronic_disease,195:214:chronic_disease
|
Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, uncontrolled cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
| 3
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NCT01644591
|
54:91:treatment
|
Patients are excluded if they are unable to obtain a magnetic resonance imaging (MRI) scan for any other reason
| 3
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NCT01555554
|
1:20:treatment
|
Epidural anesthesia
| 3
|
[
"Epidural",
"anesthesia"
] |
[
1,
1
] |
NCT02928991
|
,,49:65:chronic_disease
|
Bilirubin <2.5x normal (unless elevation due to Gilberts disease)
| 3
|
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"normal",
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NCT02106988
|
19:41:chronic_disease,60:69:treatment,89:168:chronic_disease,182:196:chronic_disease,214:232:chronic_disease,237:261:chronic_disease
|
with pre-existing cardiovascular disease requiring ongoing treatment. This includes: a) Congestive heart failure class III/IV CHF per new york heart association (NYHA) criteria. b) Cardiomyopathy, c) Uncontrolled cardiac arrhythmia, d) Unstable angina pectoris
| 3
|
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NCT02417701
|
25:64:cancer
|
Patients with untreated central nervous system (CNS) metastases
| 3
|
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NCT02484404
|
,10:27:chronic_disease
|
>5 cm or aortic dissection
| 3
|
[
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"dissection"
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0,
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2
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NCT01532687
|
37:57:treatment
|
administration of any non-oncologic investigational drug
| 3
|
[
"administration",
"of",
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"drug"
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0,
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1
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NCT02555280
|
18:26:allergy_name,28:43:allergy_name,48:87:allergy_name
|
Known allergy to titanium, titanium alloys, or MR (magnetic resonance) contrast agents
| 3
|
[
"Known",
"allergy",
"to",
"titanium",
",",
"titanium",
"alloys",
",",
"or",
"MR",
"(",
"magnetic",
"resonance",
")",
"contrast",
"agents"
] |
[
0,
0,
0,
4,
4,
0,
0,
0,
0,
4,
4,
4,
4,
4,
0,
0
] |
NCT02769156
|
34:42:allergy_name
|
Patients with a known allergy to Benadryl
| 3
|
[
"Patients",
"with",
"a",
"known",
"allergy",
"to",
"Benadryl"
] |
[
0,
0,
0,
0,
0,
0,
4
] |
NCT02476786
|
47:121:allergy_name
|
A history of allergic reactions attributed to compounds of similar chemical or biologic composition to any of the agents used in the study
| 3
|
[
"A",
"history",
"of",
"allergic",
"reactions",
"attributed",
"to",
"compounds",
"of",
"similar",
"chemical",
"or",
"biologic",
"composition",
"to",
"any",
"of",
"the",
"agents",
"used",
"in",
"the",
"study"
] |
[
0,
0,
0,
0,
0,
0,
0,
4,
4,
4,
4,
4,
4,
4,
4,
4,
4,
4,
4,
0,
0,
0,
0
] |
NCT02533882
|
1:25:chronic_disease
|
Severe pulmonary disease
| 3
|
[
"Severe",
"pulmonary",
"disease"
] |
[
2,
2,
2
] |
NCT02257138
|
17:32:treatment
|
Ability to take oral medication
| 3
|
[
"Ability",
"to",
"take",
"oral",
"medication"
] |
[
0,
0,
0,
1,
1
] |
NCT02106598
|
60:78:cancer
|
Newly-diagnosed or recurrent (local, regional, metastatic) malignant melanoma
| 3
|
[
"Newly-diagnosed",
"or",
"recurrent",
"(",
"local",
",",
"regional",
",",
"metastatic",
")",
"malignant",
"melanoma"
] |
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
3
] |
NCT01648023
|
48:79:cancer
|
who have histologic and radiologic evidence of intrahepatic cholangiocarcinoma
| 3
|
[
"who",
"have",
"histologic",
"and",
"radiologic",
"evidence",
"of",
"intrahepatic",
"cholangiocarcinoma"
] |
[
0,
0,
0,
0,
0,
0,
0,
3,
3
] |
NCT02404155
|
12:39:cancer
|
History of myeloproliferative disorder
| 3
|
[
"History",
"of",
"myeloproliferative",
"disorder"
] |
[
0,
0,
3,
3
] |
NCT01877382
|
14:82:treatment
|
Is receiving concomitant treatment with a strong inhibitor or inducer of CYP3A4/5
| 3
|
[
"Is",
"receiving",
"concomitant",
"treatment",
"with",
"a",
"strong",
"inhibitor",
"or",
"inducer",
"of",
"CYP3A4/5"
] |
[
0,
0,
1,
1,
1,
1,
1,
1,
1,
1,
1,
1
] |
NCT01793519
|
1:10:treatment,14:30:cancer,34:58:cancer,
|
Treatment of solid malignancy or non-melanoma skin cancer within the past 5 years
| 3
|
[
"Treatment",
"of",
"solid",
"malignancy",
"or",
"non-melanoma",
"skin",
"cancer",
"within",
"the",
"past",
"5",
"years"
] |
[
1,
0,
3,
3,
0,
3,
3,
3,
0,
0,
0,
0,
0
] |
NCT02680535
|
1:20:chronic_disease,,
|
renal insufficiency with an estimated glomerular filtration (EGF) <= 30
| 3
|
[
"renal",
"insufficiency",
"with",
"an",
"estimated",
"glomerular",
"filtration",
"(",
"EGF",
")",
"<",
"=",
"30"
] |
[
2,
2,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT02527200
|
24:51:chronic_disease
|
Confirmed diagnosis of PWS (Prader-Willi Syndrome) (by genetic testing)
| 3
|
[
"Confirmed",
"diagnosis",
"of",
"PWS",
"(",
"Prader-Willi",
"Syndrome",
")",
"(",
"by",
"genetic",
"testing",
")"
] |
[
0,
0,
0,
2,
2,
2,
0,
0,
0,
0,
0,
0,
0
] |
NCT02873598
|
,47:55:treatment,153:163:chronic_disease,,,212:239:treatment,,
|
This applies to any woman who has experienced menarche and who has not undergone successful surgical sterilization or is not postmenopausal (defined as amenorrhea for at least 12 consecutive months, or women on hormone replacement therapy with serum FSH levels greater than 35 mIU/mL
| 3
|
[
"This",
"applies",
"to",
"any",
"woman",
"who",
"has",
"experienced",
"menarche",
"and",
"who",
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"not",
"undergone",
"successful",
"surgical",
"sterilization",
"or",
"is",
"not",
"postmenopausal",
"(",
"defined",
"as",
"amenorrhea",
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"12",
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",",
"or",
"women",
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"hormone",
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"with",
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[
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0,
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1,
1,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT00969111
|
12:27:treatment
|
History of hip replacement
| 3
|
[
"History",
"of",
"hip",
"replacement"
] |
[
0,
0,
1,
1
] |
NCT02464436
|
1:34:treatment
|
Prior vitrectomy in the study eye
| 3
|
[
"Prior",
"vitrectomy",
"in",
"the",
"study",
"eye"
] |
[
1,
1,
1,
1,
1,
1
] |
NCT02203513
|
75:103:cancer,107:145:cancer,192:205:cancer
|
Patients enrolling in Cohort 6, the recurrent platinum-resistant sporadic high grade serous epithelial or high grade endometrioid ovarian cancer group, must have a negative family history of HBOC syndrome, or negative gBRCA1/2m test
| 3
|
[
"Patients",
"enrolling",
"in",
"Cohort",
"6",
",",
"the",
"recurrent",
"platinum-resistant",
"sporadic",
"high",
"grade",
"serous",
"epithelial",
"or",
"high",
"grade",
"endometrioid",
"ovarian",
"cancer",
"group",
",",
"must",
"have",
"a",
"negative",
"family",
"history",
"of",
"HBOC",
"syndrome",
",",
"or",
"negative",
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0,
0,
0,
0,
0,
0,
3,
3,
0,
0,
0,
0,
0
] |
NCT00896493
|
21:33:cancer,
|
Patients with prior malignancies diagnosed > 5 years ago without evidence of disease
| 3
|
[
"Patients",
"with",
"prior",
"malignancies",
"diagnosed",
">",
"5",
"years",
"ago",
"without",
"evidence",
"of",
"disease"
] |
[
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT02503722
|
48:76:treatment,80:97:treatment,99:129:treatment,135:164:treatment
|
Inability to discontinue drugs that are strong cytochrome P450 3A4 (CYP3A4) or P450 3A5 (CYP3A5), cytochrome P450 2C19 (CYP2C19), and cytochrome P450 2C9 (CYP 2C9) inhibitors and/or inducers
| 3
|
[
"Inability",
"to",
"discontinue",
"drugs",
"that",
"are",
"strong",
"cytochrome",
"P450",
"3A4",
"(",
"CYP3A4",
")",
"or",
"P450",
"3A5",
"(",
"CYP3A5",
")",
",",
"cytochrome",
"P450",
"2C19",
"(",
"CYP2C19",
")",
",",
"and",
"cytochrome",
"P450",
"2C9",
"(",
"CYP",
"2C9",
")",
"inhibitors",
"and/or",
"inducers"
] |
[
0,
0,
0,
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0,
0,
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0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT02851290
|
1:32:treatment
|
Previous hypospadias operations
| 3
|
[
"Previous",
"hypospadias",
"operations"
] |
[
1,
1,
1
] |
NCT00488696
|
21:36:chronic_disease
|
Serious systemic or groin infection
| 3
|
[
"Serious",
"systemic",
"or",
"groin",
"infection"
] |
[
0,
0,
0,
2,
2
] |
NCT01554371
|
22:30:treatment,43:55:chronic_disease,71:91:treatment
|
Patients must be off steroids with no new CNS symptoms or findings on radiographic imaging for 1 month
| 3
|
[
"Patients",
"must",
"be",
"off",
"steroids",
"with",
"no",
"new",
"CNS",
"symptoms",
"or",
"findings",
"on",
"radiographic",
"imaging",
"for",
"1",
"month"
] |
[
0,
0,
0,
0,
1,
0,
0,
0,
2,
2,
0,
0,
0,
1,
1,
0,
0,
0
] |
NCT02819440
|
12:33:chronic_disease,35:41:chronic_disease,56:74:chronic_disease,76:82:chronic_disease,84:109:chronic_disease,114:121:chronic_disease
|
History of myocardial infarction, angina, uncontrolled cardiac arrhythmia, stroke, transient ischemic attack, or seizure
| 3
|
[
"History",
"of",
"myocardial",
"infarction",
",",
"angina",
",",
"uncontrolled",
"cardiac",
"arrhythmia",
",",
"stroke",
",",
"transient",
"ischemic",
"attack",
",",
"or",
"seizure"
] |
[
0,
0,
2,
2,
0,
2,
0,
0,
2,
2,
0,
2,
0,
2,
2,
2,
0,
0,
2
] |
NCT02910700
|
33:50:treatment
|
patients who have progressed on anti-PD-1 therapy in the adjuvant setting are also allowed
| 3
|
[
"patients",
"who",
"have",
"progressed",
"on",
"anti-PD-1",
"therapy",
"in",
"the",
"adjuvant",
"setting",
"are",
"also",
"allowed"
] |
[
0,
0,
0,
0,
0,
1,
1,
0,
0,
0,
0,
0,
0,
0
] |
NCT02844751
|
15:56:chronic_disease
|
Patients with adequate cardiac and respiratory function
| 3
|
[
"Patients",
"with",
"adequate",
"cardiac",
"and",
"respiratory",
"function"
] |
[
0,
0,
2,
2,
2,
2,
2
] |
NCT02446886
|
35:38:treatment
|
Patients unwilling to have serial MRI exams
| 3
|
[
"Patients",
"unwilling",
"to",
"have",
"serial",
"MRI",
"exams"
] |
[
0,
0,
0,
0,
0,
1,
0
] |
NCT02593110
|
42:75:treatment
|
potential participants with a history of lower extremity revascularization who do not meet the criterion above
| 3
|
[
"potential",
"participants",
"with",
"a",
"history",
"of",
"lower",
"extremity",
"revascularization",
"who",
"do",
"not",
"meet",
"the",
"criterion",
"above"
] |
[
0,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0
] |
NCT03053908
|
1:8:chronic_disease
|
bipolar
| 3
|
[
"bipolar"
] |
[
2
] |
NCT02562755
|
,,34:81:treatment
|
Performance status 0 or 1 on the Eastern Cooperative Oncology Group (ECOG) scale
| 3
|
[
"Performance",
"status",
"0",
"or",
"1",
"on",
"the",
"Eastern",
"Cooperative",
"Oncology",
"Group",
"(",
"ECOG",
")",
"scale"
] |
[
0,
0,
0,
0,
0,
0,
0,
1,
1,
1,
1,
1,
1,
0,
0
] |
NCT02519322
|
1:34:treatment,36:46:treatment,48:58:treatment,63:83:treatment
|
Prior treatment with an anti-PD-1, anti-PD-L1, anti-LAG-3, or anti-CTLA-4 antibody
| 3
|
[
"Prior",
"treatment",
"with",
"an",
"anti-PD-1",
",",
"anti-PD-L1",
",",
"anti-LAG-3",
",",
"or",
"anti-CTLA-4",
"antibody"
] |
[
1,
1,
1,
1,
1,
0,
1,
0,
1,
0,
0,
1,
1
] |
NCT02310464
|
15:28:chronic_disease,37:58:chronic_disease,69:90:chronic_disease
|
Subjects with HIV infection, active hepatitis B infection or active hepatitis C infection
| 3
|
[
"Subjects",
"with",
"HIV",
"infection",
",",
"active",
"hepatitis",
"B",
"infection",
"or",
"active",
"hepatitis",
"C",
"infection"
] |
[
0,
0,
2,
2,
0,
0,
2,
2,
2,
0,
0,
0,
0,
0
] |
NCT02392286
|
18:40:treatment
|
Patients in whom corticosteroid therapy is contraindicated
| 3
|
[
"Patients",
"in",
"whom",
"corticosteroid",
"therapy",
"is",
"contraindicated"
] |
[
0,
0,
0,
1,
1,
0,
0
] |
NCT02252588
|
33:46:allergy_name
|
Known allergy or sensitivity to chlorhexidine
| 3
|
[
"Known",
"allergy",
"or",
"sensitivity",
"to",
"chlorhexidine"
] |
[
0,
0,
0,
0,
0,
4
] |
NCT03071393
|
20:47:chronic_disease,49:60:chronic_disease,65:77:chronic_disease
|
Presence of severe musculoskeletal impairments, open wounds, or skin lesions that would limit participation in functional assessments
| 3
|
[
"Presence",
"of",
"severe",
"musculoskeletal",
"impairments",
",",
"open",
"wounds",
",",
"or",
"skin",
"lesions",
"that",
"would",
"limit",
"participation",
"in",
"functional",
"assessments"
] |
[
0,
0,
0,
2,
2,
0,
2,
2,
0,
0,
2,
2,
0,
0,
0,
0,
0,
0,
0
] |
NCT02245841
|
1:11:treatment
|
adalimumab
| 3
|
[
"adalimumab"
] |
[
1
] |
NCT03133013
|
18:39:treatment
|
Participating in other clinical trials
| 3
|
[
"Participating",
"in",
"other",
"clinical",
"trials"
] |
[
0,
0,
1,
1,
1
] |
NCT02734602
|
31:37:chronic_disease
|
No current, or history of any DSM-IV diagnosis
| 3
|
[
"No",
"current",
",",
"or",
"history",
"of",
"any",
"DSM-IV",
"diagnosis"
] |
[
0,
0,
0,
0,
0,
0,
0,
2,
0
] |
NCT02140255
|
99:110:treatment
|
NVP dosing must be at least equivalent to current country or local standard dosing guidelines for prophylaxis
| 3
|
[
"NVP",
"dosing",
"must",
"be",
"at",
"least",
"equivalent",
"to",
"current",
"country",
"or",
"local",
"standard",
"dosing",
"guidelines",
"for",
"prophylaxis"
] |
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1
] |
NCT02160288
|
47:63:treatment
|
Inability to relax the puborectalis muscle at electromyography
| 3
|
[
"Inability",
"to",
"relax",
"the",
"puborectalis",
"muscle",
"at",
"electromyography"
] |
[
0,
0,
0,
0,
0,
0,
0,
1
] |
NCT02971202
|
1:11:treatment
|
metoprolol
| 3
|
[
"metoprolol"
] |
[
1
] |
NCT02253316
|
7:17:chronic_disease,21:33:treatment,96:104:treatment
|
Known GI disease or GI procedure that could interfere with the oral absorption or tolerance of ixazomib
| 3
|
[
"Known",
"GI",
"disease",
"or",
"GI",
"procedure",
"that",
"could",
"interfere",
"with",
"the",
"oral",
"absorption",
"or",
"tolerance",
"of",
"ixazomib"
] |
[
0,
1,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1
] |
NCT02135588
|
,,,,,,,286:296:treatment
|
Women of child-bearing potential (i.e., women who are pre-menopausal or not surgically sterile) must be willing to use an acceptable contraceptive method (abstinence, oral contraceptive or double barrier method) for the duration of the study and for 30 days following the last dose of study drug
| 3
|
[
"Women",
"of",
"child-bearing",
"potential",
"(",
"i.e.",
",",
"women",
"who",
"are",
"pre-menopausal",
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"must",
"be",
"willing",
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"the",
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[
0,
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0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT02542657
|
,,,126:144:treatment
|
Failure to have fully recovered (i.e., =< grade 1 toxicity or to patient's clinical baseline) from the reversible effects of prior chemotherapy
| 3
|
[
"Failure",
"to",
"have",
"fully",
"recovered",
"(",
"i.e.",
",",
"=",
"<",
"grade",
"1",
"toxicity",
"or",
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"clinical",
"baseline",
")",
"from",
"the",
"reversible",
"effects",
"of",
"prior",
"chemotherapy"
] |
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1
] |
NCT02520778
|
35:76:chronic_disease,
|
Patients with a recent history of non-chemotherapy-induced thrombocytopenic-associated bleeding within 1 year prior to the first dose of study drug
| 3
|
[
"Patients",
"with",
"a",
"recent",
"history",
"of",
"non-chemotherapy-induced",
"thrombocytopenic-associated",
"bleeding",
"within",
"1",
"year",
"prior",
"to",
"the",
"first",
"dose",
"of",
"study",
"drug"
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0,
0,
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0,
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0,
0,
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0,
0,
0
] |
NCT03137771
|
29:62:treatment
|
Patients must have received first-line/induction chemotherapy (4 cycles) and achieved stable disease or a partial response
| 3
|
[
"Patients",
"must",
"have",
"received",
"first-line/induction",
"chemotherapy",
"(",
"4",
"cycles",
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"and",
"achieved",
"stable",
"disease",
"or",
"a",
"partial",
"response"
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0,
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1,
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0,
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0,
0,
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0,
0
] |
NCT03113760
|
1:16:chronic_disease
|
XIAP deficiency (caused by BIRC4 gene mutation)
| 3
|
[
"XIAP",
"deficiency",
"(",
"caused",
"by",
"BIRC4",
"gene",
"mutation",
")"
] |
[
2,
2,
0,
0,
0,
0,
0,
0,
0
] |
NCT02459119
|
46:51:chronic_disease
|
Presence of a non-healing wound, non-healing ulcer, or bone fracture
| 3
|
[
"Presence",
"of",
"a",
"non-healing",
"wound",
",",
"non-healing",
"ulcer",
",",
"or",
"bone",
"fracture"
] |
[
0,
0,
0,
0,
0,
0,
0,
2,
0,
0,
0,
0
] |
NCT02427581
|
14:34:chronic_disease,76:92:chronic_disease,106:130:chronic_disease,132:156:chronic_disease,158:176:chronic_disease,188:205:chronic_disease,211:230:chronic_disease
|
Uncontrolled intercurrent illness including, but not limited to ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia (including sinus bradycardia), or psychiatric illness/social situation that would limit compliance with study requirements
| 3
|
[
"Uncontrolled",
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"but",
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2,
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0,
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0,
0
] |
NCT02441140
|
15:22:treatment,85:115:cancer,,145:156:chronic_disease,158:165:chronic_disease,171:185:cancer
|
Scheduled for surgery at Brigham and Women's Hospital for known or highly suspected Stage III or IV ovarian cancer (i.e. elevated CA-125 with a pelvic mass, ascites, and carcinomatosis)
| 3
|
[
"Scheduled",
"for",
"surgery",
"at",
"Brigham",
"and",
"Women",
"'s",
"Hospital",
"for",
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"suspected",
"Stage",
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"or",
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] |
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0,
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0,
0,
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2,
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0,
0,
3,
0
] |
NCT02131805
|
1:26:chronic_disease,28:33:chronic_disease,35:46:chronic_disease,48:68:chronic_disease
|
Collagen vascular disease (lupus, scleroderma, rheumatoid arthritis)
| 3
|
[
"Collagen",
"vascular",
"disease",
"(",
"lupus",
",",
"scleroderma",
",",
"rheumatoid",
"arthritis",
")"
] |
[
2,
2,
2,
0,
2,
0,
2,
0,
2,
2,
0
] |
NCT02232165
|
26:49:chronic_disease,65:89:chronic_disease,91:94:treatment,113:121:treatment
|
Known uncorrected severe coronary artery disease or evidence of active coronary ischemia (ECG changes, positive troponin)
| 3
|
[
"Known",
"uncorrected",
"severe",
"coronary",
"artery",
"disease",
"or",
"evidence",
"of",
"active",
"coronary",
"ischemia",
"(",
"ECG",
"changes",
",",
"positive",
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] |
[
0,
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2,
2,
0,
0,
0,
2,
2,
2,
0,
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0,
0,
0,
1,
0
] |
NCT02595866
|
22:30:chronic_disease
|
Clinical evidence of vitiligo or other forms of depigmenting illness
| 3
|
[
"Clinical",
"evidence",
"of",
"vitiligo",
"or",
"other",
"forms",
"of",
"depigmenting",
"illness"
] |
[
0,
0,
0,
2,
0,
0,
0,
0,
0,
0
] |
NCT03114020
|
12:27:treatment
|
History of lung transplant
| 3
|
[
"History",
"of",
"lung",
"transplant"
] |
[
0,
0,
1,
1
] |
NCT02908906
|
1:25:chronic_disease
|
unstable angina pectoris
| 3
|
[
"unstable",
"angina",
"pectoris"
] |
[
2,
2,
2
] |
NCT03113695
|
14:31:chronic_disease
|
Uncontrolled diabetes mellitus
| 3
|
[
"Uncontrolled",
"diabetes",
"mellitus"
] |
[
0,
2,
2
] |
NCT02332668
|
,125:141:treatment
|
expecting to conceive or father children within the projected duration of the trial through 120 days after the last dose of study medication
| 3
|
[
"expecting",
"to",
"conceive",
"or",
"father",
"children",
"within",
"the",
"projected",
"duration",
"of",
"the",
"trial",
"through",
"120",
"days",
"after",
"the",
"last",
"dose",
"of",
"study",
"medication"
] |
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
1
] |
NCT02287337
|
77:82:cancer,94:112:chronic_disease,114:134:chronic_disease,136:148:chronic_disease
|
Red flags noted in the patient's Neck Medical Screening Questionnaire (i.e. tumor, fracture, metabolic diseases, Rheumatoid Arthritis, osteoporosis, prolonged history of steroid use, etc.)
| 3
|
[
"Red",
"flags",
"noted",
"in",
"the",
"patient",
"'s",
"Neck",
"Medical",
"Screening",
"Questionnaire",
"(",
"i.e",
".",
"tumor",
",",
"fracture",
",",
"metabolic",
"diseases",
",",
"Rheumatoid",
"Arthritis",
",",
"osteoporosis",
",",
"prolonged",
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",",
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".",
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0,
0,
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2,
2,
0,
2,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT02525861
|
35:57:chronic_disease,
|
The participant is experiencing a pulmonary exacerbation at the time of screening (participant may be re-screened 4 weeks after the clinical resolution of an exacerbation)
| 3
|
[
"The",
"participant",
"is",
"experiencing",
"a",
"pulmonary",
"exacerbation",
"at",
"the",
"time",
"of",
"screening",
"(",
"participant",
"may",
"be",
"re-screened",
"4",
"weeks",
"after",
"the",
"clinical",
"resolution",
"of",
"an",
"exacerbation",
")"
] |
[
0,
0,
0,
0,
0,
2,
2,
0,
0,
0,
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0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT02442102
|
20:31:chronic_disease
|
Known or suspected sleep apnea (treated or untreated)
| 3
|
[
"Known",
"or",
"suspected",
"sleep",
"apnea",
"(",
"treated",
"or",
"untreated",
")"
] |
[
0,
0,
0,
2,
2,
0,
0,
0,
0,
0
] |
NCT00338377
|
34:47:treatment,40:47:treatment,49:65:treatment,118:134:treatment
|
Patients previously treated with immunotherapy, targeted therapy, or no therapy will be eligible. Patients receiving cytotoxic agents will be evaluated by the PI or his designee as to suitable eligibility. (Turnstile I)
| 3
|
[
"Patients",
"previously",
"treated",
"with",
"immunotherapy",
",",
"targeted",
"therapy",
",",
"or",
"no",
"therapy",
"will",
"be",
"eligible",
".",
"Patients",
"receiving",
"cytotoxic",
"agents",
"will",
"be",
"evaluated",
"by",
"the",
"PI",
"or",
"his",
"designee",
"as",
"to",
"suitable",
"eligibility",
".",
"(",
"Turnstile",
"I",
")"
] |
[
0,
0,
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0,
0,
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0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT01584076
|
13:20:chronic_disease,32:38:chronic_disease,40:69:chronic_disease,71:87:chronic_disease,89:109:chronic_disease,118:138:chronic_disease,160:166:treatment
|
Presence of cardiac condition, asthma, obstructive pulmonary disease, seizure disorder, urinary incontinence, and/or peptic ulcer disease receiving concurrent NSAIDs
| 3
|
[
"Presence",
"of",
"cardiac",
"condition",
",",
"asthma",
",",
"obstructive",
"pulmonary",
"disease",
",",
"seizure",
"disorder",
",",
"urinary",
"incontinence",
",",
"and/or",
"peptic",
"ulcer",
"disease",
"receiving",
"concurrent",
"NSAIDs"
] |
[
0,
0,
2,
0,
0,
2,
0,
2,
2,
2,
0,
2,
2,
0,
2,
2,
0,
0,
2,
2,
2,
0,
0,
1
] |
NCT02624804
|
23:42:chronic_disease,44:49:chronic_disease,51:71:chronic_disease,73:84:chronic_disease
|
Presence of any other autoimmune diseases (lupus, rheumatoid arthritis, scleroderma, etc.)
| 3
|
[
"Presence",
"of",
"any",
"other",
"autoimmune",
"diseases",
"(",
"lupus",
",",
"rheumatoid",
"arthritis",
",",
"scleroderma",
",",
"etc",
".",
")"
] |
[
0,
0,
0,
0,
2,
2,
0,
2,
0,
2,
2,
0,
2,
0,
0,
0,
0
] |
NCT00977977
|
52:74:chronic_disease
|
There is no evidence to suggest secondary forms of membranous nephropathy
| 3
|
[
"There",
"is",
"no",
"evidence",
"to",
"suggest",
"secondary",
"forms",
"of",
"membranous",
"nephropathy"
] |
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
2,
2
] |
NCT01919619
|
1:32:cancer
|
carcinoma in situ of the cervix
| 3
|
[
"carcinoma",
"in",
"situ",
"of",
"the",
"cervix"
] |
[
3,
3,
3,
3,
3,
3
] |
NCT02152995
|
12:36:chronic_disease,48:69:chronic_disease,74:89:chronic_disease,92:112:treatment,117:125:treatment,
|
History of acute coronary syndromes (including myocardial infarction and unstable angina), coronary angioplasty, or stenting within 6 months prior to randomization
| 3
|
[
"History",
"of",
"acute",
"coronary",
"syndromes",
"(",
"including",
"myocardial",
"infarction",
"and",
"unstable",
"angina",
")",
",",
"coronary",
"angioplasty",
",",
"or",
"stenting",
"within",
"6",
"months",
"prior",
"to",
"randomization"
] |
[
0,
0,
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1,
1,
0,
0,
2,
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2,
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0,
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0,
0,
1,
0,
0,
0,
0,
0,
0
] |
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