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NCT02468778 | 1:18:chronic_disease,,,,, | Cardiogenic shock (SBP <90 mmHg for >1 hour with either cool clammy skin OR oliguria OR altered sensorium AND cardiac index <2.2 L/min/m2) | 2 | [
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NCT01970345 | 19:38:treatment,19:29:treatment,,143:148:treatment | Must be on stable medication regimens for at least three months prior to enrollment, assuming the concomitant medication is safe for use with IGF-1 | 2 | [
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NCT03035890 | 14:34:chronic_disease | Uncontrolled intercurrent illness | 2 | [
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NCT02960555 | 1:16:treatment,42:53:treatment,55:70:treatment,72:83:treatment,85:96:treatment,98:109:treatment | Bisphosphonates are permitted, including pamidronate, zoledronic acid, alendronate, ibandronate, risedronate | 2 | [
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NCT02003222 | 83:100:treatment | Patient should be human leukocyte antigen (HLA) typed (A, B, C, DR and DQ) during induction therapy phase or a written explanation for not undergoing HLA typing on the flow sheet | 2 | [
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NCT01261728 | 9:85:treatment | Ongoing treatment with therapeutic doses of warfarin or low molecular weight heparin | 2 | [
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NCT01445821 | 11:23:chronic_disease,, | End-stage lung disease characterized by TLC<45% of predicted value | 2 | [
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NCT00065676 | 1:14:chronic_disease | heart failure | 2 | [
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NCT02003222 | 8:39:cancer | Mature B ALL (Burkitt's-like leukemia) | 2 | [
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NCT02139280 | 1:31:treatment,33:54:treatment,56:89:treatment | immunomodulatory drugs (IMiDs), proteasome inhibitors, monoclonal antibodies or steroids | 2 | [
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NCT02048722 | 34:49:chronic_disease | Active or clinically significant cardiac disease | 2 | [
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NCT02520713 | 1:25:cancer | Undifferentiated sarcoma | 2 | [
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NCT01061515 | 20:42:treatment,43:90:treatment,95:98:chronic_disease | Patients receiving antiretroviral therapy Highly Active Anti Retroviral Treatment (HAART) for HIV infection are excluded from the study because of possible pharmacokinetic interactions | 2 | [
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NCT01631617 | 8:15:treatment,19:34:treatment,,67:76:treatment | Use of topical or oral CAM agents within 4 weeks of initiation of treatment | 2 | [
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NCT02524379 | 7:19:chronic_disease, | Acute cervical SCI with ASIA Impairment Scale grade A, B or C on admission | 2 | [
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NCT03049189 | 1:6:chronic_disease,8:15:chronic_disease,17:31:chronic_disease,36:68:chronic_disease | Renal, hepatic, cardiovascular, or haematological organ dysfunction, potentially interfering with the safety of the study treatments | 2 | [
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NCT01884740 | 1:40:cancer | anaplastic mixed oligoastrocytoma (AOA) | 2 | [
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NCT02423863 | 1:14:cancer | Squamous head | 2 | [
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NCT01923662 | ,52:64:chronic_disease | Time post injury greater than six months to assure neurological and emotional stability | 2 | [
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NCT02074436 | 1:23:chronic_disease,41:67:cancer,107:150:treatment,178:192:chronic_disease, | Acute thrombocytopenia in patients with hematological malignancies who are in remission and are receiving myelosuppressive consolidation chemotherapy that is expected to induce marrow aplasia for at least 2 weeks | 2 | [
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NCT00540761 | 30:53:treatment,,, | defined as chest pain or new electrocardiogram (ECG) changes in the 12 hours prior to study entry and/or rising creatine kinase (CK) and CK-MB serum enzymes | 2 | [
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NCT02819440 | ,,89:102:chronic_disease | Estimated glomerular filtration rate (eGFR) < 60 ml/min/1.73 m2 by the modified diet in renal disease (MDRD) equation | 2 | [
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NCT02693145 | 74:87:chronic_disease, | Residents within the health department jurisdiction with newly diagnosed HIV infection who have not linked to medical care within 90 days | 2 | [
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NCT02555189 | 32:45:chronic_disease | Patient has a known history of HIV infection (testing not mandatory) | 2 | [
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NCT03009110 | 14:23:chronic_disease | Pre-existing infection around incision site | 2 | [
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NCT02273375 | 12:21:treatment,33:54:treatment,58:77:treatment | Concurrent treatment with other investigational drugs or anti-cancer therapy | 2 | [
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NCT02744391 | 38:55:chronic_disease,57:75:chronic_disease,77:103:chronic_disease,118:140:chronic_disease,185:208:chronic_disease | Presence of a clinically significant brain abnormality, significant anemia, insulin dependent diabetes, a history of cardiovascular disease, or uncontrolled/untreated risk factors for coronary artery disease | 2 | [
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NCT02355535 | 23:34:cancer,38:60:cancer,73:81:cancer,123:139:treatment | Diagnosis of advanced solid tumor or hematologic malignancy (limited to lymphoma) that has failed or become intolerant to standard therapy | 2 | [
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NCT02977299 | 17:31:treatment,,, | currently on an antidepressant of adequate dose (as defined by the MGH ATRQ) and duration (at least 8 weeks), with the antidepressant dose being stable over the past four weeks, and with documented (in the MGH ATRQ) non-response (less than 50% improvement) to the current antidepressant | 2 | [
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NCT01853163 | 29:43:chronic_disease | patient has stable impaired renal function | 2 | [
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NCT02270619 | ,,32:39:chronic_disease | BMI > 35 due to the effects of obesity on cytokine activity and risk for sleep disordered breathing | 2 | [
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NCT01973283 | 37:52:chronic_disease | Patient is considered a significant risk of suicide | 2 | [
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NCT02016781 | 1:56:chronic_disease | Refractory cytopenia with multilineage dysplasia (RCMD) | 2 | [
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NCT02134392 | 48:52:allergy_name | Recent ingestion of a potential allergen (e.g. nuts) where recipient has a known allergy to this (these) agent(s) | 2 | [
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NCT02553941 | 5:29:chronic_disease,31:48:chronic_disease,53:77:chronic_disease | Any life-threatening illness, medical condition, or organ system dysfunction that, in the investigator's opinion, could compromise the subject's safety or put the study outcomes at undue risk | 2 | [
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NCT01522768 | 51:57:treatment,123:131:treatment,139:155:cancer,180:189:treatment,209:218:treatment,225:227:treatment | All patients with disease technically amenable to biopsy will be asked to undergo a biopsy. Patient must agree to allow 2 biopsies of any malignant lesion that can be accessed by endoscopy or with the aid or radiology (i.e. CT guided) | 2 | [
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NCT02501954 | 1:18:chronic_disease | Pelvic lymph node sampling | 2 | [
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NCT02180412 | 1:19:treatment, | Therapy with hemin within 7 days prior to enrollment in this study | 2 | [
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NCT02487095 | 30:34:cancer,39:71:cancer,146:155:treatment | Histological confirmation of SCLC, or extrapulmonary small cell cancer. Although NCI confirmation of pathology is not required prior to starting treatment, every effort will be made to obtain outside pathology to be reviewed by an NCI pathologist | 2 | [
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NCT02572323 | 8:18:cancer,30:35:cancer,39:59:cancer | Active malignancy other than basal or squamous skin cancer | 2 | [
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NCT02169037 | 24:52:chronic_disease,54:70:chronic_disease,74:95:chronic_disease | history of significant blood clotting abnormalities, systemic thrombi or systemic embolization | 2 | [
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NCT02648282 | 54:74:chronic_disease | Conditions, including alcohol or drug dependence, or intercurrent illness that would affect the patient's ability to comply with study visits and procedures | 2 | [
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NCT02016781 | 1:17:treatment | Prior autologous | 2 | [
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NCT02186418 | 144:150:chronic_disease | weaning transfusions is necessary, so that a selective pressure on gene-modified red blood cells is evident, and this will place subjects with stroke risk at risk for a recurrent stroke | 2 | [
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NCT02203513 | 14:34:chronic_disease,78:102:chronic_disease,113:128:chronic_disease,138:148:chronic_disease,173:184:chronic_disease,188:198:chronic_disease,,250:269:chronic_disease | Uncontrolled intercurrent illness including, but not limited to, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, clinically significant GI bleeding or hemoptysis within 28 days prior to the start of the study, or psychiatric illness/social situations that would limit compliance with ... | 2 | [
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NCT02100891 | 30:50:treatment | Patients who have received a prior allogeneic HCT are ineligible | 2 | [
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NCT02440581 | 1:29:treatment, | Chronic maintenance dialysis of at least 3 months | 2 | [
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NCT02576912 | 51:63:allergy_name | Individuals with a documented reaction/allergy to Pregnenolone | 2 | [
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NCT03184389 | 48:76:treatment | Will not use non-cigarette tobacco products or nicotine replacement therapy during the study period | 2 | [
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