Datasets:
Sebasdi
/
hERG_blockers_v02

Dataset card Data Studio Files
xet
Community
1
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36
36
solution
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drug
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stringlengths
59
245
ea8246aa-f4e5-4b41-9f3c-99c2d79b2954
Yes
COc1ccc(CC[N@H+](C)CCC[C@@](C#N)(c2ccc(OC)c(OC)c2)C(C)C)cc1OC
Does the drug listed below function as a hERG inhibitor? COc1ccc(CC[N@H+](C)CCC[C@@](C#N)(c2ccc(OC)c(OC)c2)C(C)C)cc1OC
b9244345-c316-4d99-9e79-5dc8704c2048
Yes
O=C(NC1CCN(Cc2ccc3c(c2)OCO3)CC1)c1cc(=O)c2ccccc2o1
Does the drug listed below function as a hERG inhibitor? O=C(NC1CCN(Cc2ccc3c(c2)OCO3)CC1)c1cc(=O)c2ccccc2o1
1b84458b-b6bb-43b3-9a1a-ee9ea67cc5fc
No
CC(C)CC([NH+](C)C)C1(c2ccc(Cl)cc2)CCC1
Does the specified drug exhibit hERG blocking activity? CC(C)CC([NH+](C)C)C1(c2ccc(Cl)cc2)CCC1
135efbfa-1736-4874-813f-b864a35209ba
Yes
C[NH2+]CCCC1c2ccccc2C=Cc2ccccc21
Does the specified drug exhibit hERG blocking activity? C[NH2+]CCCC1c2ccccc2C=Cc2ccccc21
52b36e8c-fd4a-42f2-a185-eaf2f6f03003
Yes
COc1cc(N)c(Cl)cc1C(=O)N[C@@H]1CC[NH+](CCCOc2ccc(F)cc2)C[C@@H]1OC
Check whether the given drug blocks hERG channels. COc1cc(N)c(Cl)cc1C(=O)N[C@@H]1CC[NH+](CCCOc2ccc(F)cc2)C[C@@H]1OC
8d3bda7e-c6ae-4b5e-9ee2-b4f17f1b844a
Yes
CC[C@@H](O)c1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12
Check whether the given drug blocks hERG channels. CC[C@@H](O)c1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12
cd965a6d-f075-4da3-a77b-3cd97877afd7
Yes
CCC(=O)N(c1ccccc1)C1CC[NH+](CCc2ccccc2)CC1
Verify if this drug has hERG blocking properties. CCC(=O)N(c1ccccc1)C1CC[NH+](CCc2ccccc2)CC1
bedc738a-c7fa-4c1a-aa60-4bb798921682
No
C[NH+]1[C@H]2CC[C@@H]1[C@@H](C(=O)[O-])[C@H](OC(=O)c1ccccc1)C2
Verify if this drug has hERG blocking properties. C[NH+]1[C@H]2CC[C@@H]1[C@@H](C(=O)[O-])[C@H](OC(=O)c1ccccc1)C2
7a24e4eb-cf10-4ac7-9ccc-149da3773a9f
Yes
CC(=O)OCOC(=O)CN(CC(=O)O)c1ccccc1OCCOc1ccccc1N(CC(=O)O)CC(=O)O
Is the drug in question known to block hERG channels? CC(=O)OCOC(=O)CN(CC(=O)O)c1ccccc1OCCOc1ccccc1N(CC(=O)O)CC(=O)O
e2662210-e29a-49f0-b1cc-7a70287ff911
No
CCCC1=N[N+](C)=C2C(=O)N=C(c3cc(S(=O)(=O)N4CC[NH+](C)CC4)ccc3OCC)N=C12
Verify if this drug has hERG blocking properties. CCCC1=N[N+](C)=C2C(=O)N=C(c3cc(S(=O)(=O)N4CC[NH+](C)CC4)ccc3OCC)N=C12
cabdacbb-15a9-4947-9fb7-f0fb88d69bdb
No
CN(C)CC(c1ccc(O)cc1)C1(O)CCCCC1
Is the drug in question known to block hERG channels? CN(C)CC(c1ccc(O)cc1)C1(O)CCCCC1
dc2d7bb5-87f1-4847-8113-16d0f2f58341
Yes
O=C1NCCN1CCN1CCC(c2cn(C3CCCCC3)c3ccc(Cl)cc23)CC1
Does this drug act as a hERG channel blocker? O=C1NCCN1CCN1CCC(c2cn(C3CCCCC3)c3ccc(Cl)cc23)CC1
1f89628a-764d-4ffd-98af-1df3cfd83687
Yes
CN1CCN2c3ccccc3Cc3ccccc3[C@@H]2C1
Determine if the following medication inhibits hERG potassium channels. CN1CCN2c3ccccc3Cc3ccccc3[C@@H]2C1
f84d5844-4d76-4e9b-b8eb-b1e7bd598d6d
Yes
CC(C)(C)C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1cccc(O)c1
Does the drug listed below function as a hERG inhibitor? CC(C)(C)C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1cccc(O)c1
9c06f088-f62c-4214-9c5f-9e311a72e921
Yes
COc1ccccc1OCC[NH2+]C[C@@H](O)COC1=CC=CC2=Nc3ccccc3[C@@H]12
Is the drug provided capable of blocking hERG channels? COc1ccccc1OCC[NH2+]C[C@@H](O)COC1=CC=CC2=Nc3ccccc3[C@@H]12
0fc1040c-c3bf-4d4e-af49-21dbff7372ae
Yes
CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCC[NH+](CC)CC)c(I)c1
Does the specified drug exhibit hERG blocking activity? CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCC[NH+](CC)CC)c(I)c1
141640c0-cb24-4480-b08b-25749b3cf233
Yes
COc1ccc(CC(=O)NCc2ccccc2-c2ccccc2C(=O)NCCc2cccnc2)cc1
Check whether the given drug blocks hERG channels. COc1ccc(CC(=O)NCc2ccccc2-c2ccccc2C(=O)NCCc2cccnc2)cc1
f6898908-571e-4d1d-a368-90864cfa20fe
Yes
CC(=O)N1CCN(c2ccc(OC[C@@H]3CO[C@](Cn4ccnc4)(c4ccc(Cl)cc4Cl)O3)cc2)CC1
Verify if this drug has hERG blocking properties. CC(=O)N1CCN(c2ccc(OC[C@@H]3CO[C@](Cn4ccnc4)(c4ccc(Cl)cc4Cl)O3)cc2)CC1
3325b374-86b9-429e-9577-9b1c8cf1add8
Yes
Nc1nc(N)c2nc(-c3ccccc3)c(N)nc2n1
Verify if this drug has hERG blocking properties. Nc1nc(N)c2nc(-c3ccccc3)c(N)nc2n1
7b21fc6d-d0db-42d2-ad08-6319417e0e1f
Yes
CC(C)[NH2+]C[C@@H](O)COc1cccc2ccccc12
Does the specified drug exhibit hERG blocking activity? CC(C)[NH2+]C[C@@H](O)COc1cccc2ccccc12
7b13e627-28ee-408d-9c78-0d609944c459
Yes
CN(CCO)C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1cccc(O)c1
Is the drug in question known to block hERG channels? CN(CCO)C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1cccc(O)c1
0b9feba2-9c07-479e-82d4-109268527b9d
Yes
O=C(O[C@@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1
Check whether the given drug blocks hERG channels. O=C(O[C@@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1
071ab7fb-4fba-4901-8abc-a9c81e030eb2
Yes
C[NH+](C)CC/C=C1/c2ccccc2COc2ccccc21
Is the drug in question known to block hERG channels? C[NH+](C)CC/C=C1/c2ccccc2COc2ccccc21
429095db-329b-4c6a-8bb5-28d151ea1986
Yes
CC(CN1c2ccccc2CCc2ccccc21)C[NH+](C)C
Is the drug in question known to block hERG channels? CC(CN1c2ccccc2CCc2ccccc21)C[NH+](C)C
3a2b6d81-6fc9-4c35-a0a3-07aa07b179e1
No
OC(c1ccc(F)cc1)c1ccc(F)cc1
Does the drug listed below function as a hERG inhibitor? OC(c1ccc(F)cc1)c1ccc(F)cc1
14657ad1-f104-4e5a-9af3-10ee8abd3761
Yes
CCN(CC)Cc1ccc2c(c1)CC[C@H](N1CCN(CCC3CCCCC3)CC1=O)C2
Does this drug act as a hERG channel blocker? CCN(CC)Cc1ccc2c(c1)CC[C@H](N1CCN(CCC3CCCCC3)CC1=O)C2
94cc5924-e4ff-4ac6-b0d2-5d1e7f553392
Yes
CCOC(=O)C1=C[C@]2(CC)CCC[NH+]3CCc4c(n1c1ccccc41)[C@H]32
Is this pharmaceutical compound a blocker of the hERG ion channel? CCOC(=O)C1=C[C@]2(CC)CCC[NH+]3CCc4c(n1c1ccccc41)[C@H]32
9a8e017f-2653-4121-97b8-c9b4ecbee01f
Yes
CC(C)(O)c1ccc([C@H](O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1
Determine if the following medication inhibits hERG potassium channels. CC(C)(O)c1ccc([C@H](O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1
12639486-b2f0-4a97-b3ad-01ef9caa4b1c
Yes
O[C@H](CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1
Does the drug listed below function as a hERG inhibitor? O[C@H](CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1
cacfda23-d602-4690-a003-3e92f11d59c6
Yes
CC/C(=C(\c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
Is the drug in question known to block hERG channels? CC/C(=C(\c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
6b1265a0-7a6e-4830-bf9e-6f468c716ac7
Yes
CC(C)COC[C@@H](CN(Cc1ccccc1)c1ccccc1)[NH+]1CCCC1
Check whether the given drug blocks hERG channels. CC(C)COC[C@@H](CN(Cc1ccccc1)c1ccccc1)[NH+]1CCCC1
4c4464f6-5c41-408f-b3bf-5b19e5e5afcf
No
CC(C)[NH+](CC[C@](C(N)=O)(c1ccccc1)c1ccccn1)C(C)C
Does this drug act as a hERG channel blocker? CC(C)[NH+](CC[C@](C(N)=O)(c1ccccc1)c1ccccn1)C(C)C
f100946a-d480-4168-b9c0-35a439e1be07
Yes
O=C([C@H](O)C1CC1)N1CC(c2cc(F)ccc2F)=C[C@@H]1c1ccccc1
Is the drug in question known to block hERG channels? O=C([C@H](O)C1CC1)N1CC(c2cc(F)ccc2F)=C[C@@H]1c1ccccc1
63a169fa-c420-4a88-9336-7fcacc1edb53
Yes
C[C@@H](CN(C)C)[C@](C)(O)Cc1ccc(Cl)cc1
Is the drug provided capable of blocking hERG channels? C[C@@H](CN(C)C)[C@](C)(O)Cc1ccc(Cl)cc1
16506cd1-44ee-49ae-8a38-319d84b4bbbc
Yes
C[C@H]1CN(c2ncccc2F)CCN1/C(=N/C#N)Nc1ccc(C(C)(C)C)cc1
Is the drug provided capable of blocking hERG channels? C[C@H]1CN(c2ncccc2F)CCN1/C(=N/C#N)Nc1ccc(C(C)(C)C)cc1
9f43e36e-856c-46ff-a234-4c7bce80c144
Yes
Cc1ccc(O)c([C@H](CC[NH+](C(C)C)C(C)C)c2ccccc2)c1
Assess if the following substance is a hERG blocker. Cc1ccc(O)c([C@H](CC[NH+](C(C)C)C(C)C)c2ccccc2)c1
d0e6ec2d-1415-4293-a52d-2a6a5296ca83
Yes
CC1=C(C/C=C(\C)CCCC(C)CCCC(C)CCCC(C)C)C(=O)c2ccccc2C1=O
Does this drug act as a hERG channel blocker? CC1=C(C/C=C(\C)CCCC(C)CCCC(C)CCCC(C)C)C(=O)c2ccccc2C1=O
344d1427-0a84-44b9-ae87-f09aa78fc0c6
No
Cc1ncc(CO)c(CO)c1O
Verify if this drug has hERG blocking properties. Cc1ncc(CO)c(CO)c1O
9d794876-7420-4019-9676-48a4a82b2f5d
Yes
C[NH+]1CCCC[C@@H]1CCN1c2ccccc2Sc2ccc(S(C)=O)cc21
Is this pharmaceutical compound a blocker of the hERG ion channel? C[NH+]1CCCC[C@@H]1CCN1c2ccccc2Sc2ccc(S(C)=O)cc21
5acceb68-5419-4954-a9ee-fb25585e2efd
Yes
COc1ccc(CCN(C)CCCN(C(=O)c2ccc([N+](=O)[O-])cc2)c2ccc(OC)c(OC)c2)cc1OC
Verify if this drug has hERG blocking properties. COc1ccc(CCN(C)CCCN(C(=O)c2ccc([N+](=O)[O-])cc2)c2ccc(OC)c(OC)c2)cc1OC
d8f98937-7cd6-4692-8fcf-d612163337b8
No
N[C@H](CCCCO)C(=O)O
Does the drug listed below function as a hERG inhibitor? N[C@H](CCCCO)C(=O)O
b033f96b-40eb-4391-8586-f92b22dfcd6c
No
COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1ccccc1[N+](=O)[O-]
Does the drug listed below function as a hERG inhibitor? COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1ccccc1[N+](=O)[O-]
ca6e0480-6d34-4dbd-a93d-fe44a7084234
Yes
Fc1ccc(-n2cc(C3CCNCC3)c3cc(Cl)ccc32)cc1
Is the drug in question known to block hERG channels? Fc1ccc(-n2cc(C3CCNCC3)c3cc(Cl)ccc32)cc1
13cc5ece-31c1-4325-b068-99a3eab1c554
No
CCCc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12
Check whether the given drug blocks hERG channels. CCCc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12
2086d2a8-a8ec-4f0a-ba8d-a33036348000
Yes
CC1=NC2=[N+](CCCC2)C(=O)C1CC[NH+]1CCC(c2noc3cc(F)ccc23)CC1
Does the specified drug exhibit hERG blocking activity? CC1=NC2=[N+](CCCC2)C(=O)C1CC[NH+]1CCC(c2noc3cc(F)ccc23)CC1
38af1bf1-8546-491e-8c78-329f41c361a1
No
N=C(N)c1ccc(OCCCCCOc2ccc(C(=N)N)cc2)cc1
Is the drug provided capable of blocking hERG channels? N=C(N)c1ccc(OCCCCCOc2ccc(C(=N)N)cc2)cc1
69b44b4f-b9a9-4ee9-acc0-42495fd50f96
Yes
Clc1ccc(C(c2ccc(Cl)cc2)n2cc[n+](CC(OCc3ccc(Cl)cc3Cl)c3ccc(Cl)cc3Cl)c2)cc1
Assess if the following substance is a hERG blocker. Clc1ccc(C(c2ccc(Cl)cc2)n2cc[n+](CC(OCc3ccc(Cl)cc3Cl)c3ccc(Cl)cc3Cl)c2)cc1
bdf51a6c-2565-43de-a874-c2fc8431c6ad
No
NC(=O)NOC[C@H]1NC(=O)NC1=O
Assess if the following substance is a hERG blocker. NC(=O)NOC[C@H]1NC(=O)NC1=O
f966a6c3-0f68-4eb3-b71f-e5e16ed7ea15
Yes
CC[C@@H](c1cccc(O)c1)[C@@H](C)CN(C)C
Determine if the following medication inhibits hERG potassium channels. CC[C@@H](c1cccc(O)c1)[C@@H](C)CN(C)C
e1279858-32c6-4545-b2e6-77685ddd07c5
Yes
Cc1cccc(CC[NH+]2CCC(C(=O)c3ccc(NS(C)(=O)=O)cc3)CC2)n1
Check whether the given drug blocks hERG channels. Cc1cccc(CC[NH+]2CCC(C(=O)c3ccc(NS(C)(=O)=O)cc3)CC2)n1
07291566-4101-41ee-ba2c-770e6cdd8bec
Yes
CCCC[NH+](CCCC)CC(O)c1cc(Cl)cc2c1-c1ccc(Cl)cc1/C2=C\c1ccc(Cl)cc1
Does this drug act as a hERG channel blocker? CCCC[NH+](CCCC)CC(O)c1cc(Cl)cc2c1-c1ccc(Cl)cc1/C2=C\c1ccc(Cl)cc1
83ee2800-552d-41f8-b3ff-326c92951bc1
No
Nc1nnnn1CCO
Determine if the following medication inhibits hERG potassium channels. Nc1nnnn1CCO
945138f4-13c9-4541-9f26-f36df949ea4b
Yes
Fc1cccc2c([C@@H]3C[NH2+]CC[C@@H]3F)c(-c3ccccc3)[nH]c12
Is this pharmaceutical compound a blocker of the hERG ion channel? Fc1cccc2c([C@@H]3C[NH2+]CC[C@@H]3F)c(-c3ccccc3)[nH]c12
f74dd3df-0a3f-4824-bfd6-bc68313dc8fd
Yes
O=C(OC1C[C@@H]2CC3C[C@H](C1)[NH+]2C[C@@H]3O)c1c[nH]c2ccccc12
Does this drug act as a hERG channel blocker? O=C(OC1C[C@@H]2CC3C[C@H](C1)[NH+]2C[C@@H]3O)c1c[nH]c2ccccc12
24e24834-d5de-4c6b-922c-e7f799370f0d
No
O=C1C=CC[C@@H]2[C@H]3CCCN4CCC[C@H](CN12)[C@H]34
Check whether the given drug blocks hERG channels. O=C1C=CC[C@@H]2[C@H]3CCCN4CCC[C@H](CN12)[C@H]34
23e8f85f-c421-4a9e-afab-e58a60650c09
Yes
CC(C)(C)[C@@H](NC(=O)OCCO)C(=O)N1CC(c2cc(F)ccc2F)=C[C@@H]1c1ccccc1
Check whether the given drug blocks hERG channels. CC(C)(C)[C@@H](NC(=O)OCCO)C(=O)N1CC(c2cc(F)ccc2F)=C[C@@H]1c1ccccc1
b6e14fdc-0091-4f38-9cfd-63d4fc4ebfb0
No
CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c1ccccn1
Is the drug provided capable of blocking hERG channels? CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c1ccccn1
a38a12e3-d26a-4fac-934e-e28e5b729c52
Yes
Cc1ccc2c(n1)N1[C@H](C)CNC[C@H]1C2
Does this drug act as a hERG channel blocker? Cc1ccc2c(n1)N1[C@H](C)CNC[C@H]1C2
ff891a81-04fa-4f6c-9a8d-aa963e944f78
Yes
Nc1ccc(C(=O)N2C[C@@H]3C[C@H](C2)C[NH+](Cc2ccccc2)C3)cc1
Does the drug listed below function as a hERG inhibitor? Nc1ccc(C(=O)N2C[C@@H]3C[C@H](C2)C[NH+](Cc2ccccc2)C3)cc1
4f0344ba-e2f3-4f0f-aadc-c8f10f608f62
Yes
OCC[NH+]1CC[NH+](CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1
Is the drug in question known to block hERG channels? OCC[NH+]1CC[NH+](CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1
295bc652-7492-4958-83a7-e6055657099d
No
O=C([O-])CCc1nc(-c2ccccc2)c(-c2ccccc2)o1
Is the drug in question known to block hERG channels? O=C([O-])CCc1nc(-c2ccccc2)c(-c2ccccc2)o1
bf78b59e-3aa2-4823-b4d8-420cd5d4a170
Yes
Fc1ccc2c(C3C[NH2+]CCC3F)c(-c3ccsc3)[nH]c2c1
Does the specified drug exhibit hERG blocking activity? Fc1ccc2c(C3C[NH2+]CCC3F)c(-c3ccsc3)[nH]c2c1
151e7a18-d32c-4d3c-b968-fc9d65278787
Yes
COc1ccc(C(=O)N2CCN(c3ccc4c(c3)CCC(=O)N4)CC2)cc1OC
Verify if this drug has hERG blocking properties. COc1ccc(C(=O)N2CCN(c3ccc4c(c3)CCC(=O)N4)CC2)cc1OC
4e94886f-febd-4bd8-88e7-9c99bf13e90e
No
CC[C@H]1OC(=O)[C@H](C)[C@H](O[C@H]2C[C@](C)(OC)[C@H](O)[C@@H](C)O2)[C@@H](C)[C@@H](O[C@H]2O[C@H](C)C[C@@H]([NH+](C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@@]1(C)O
Does this drug act as a hERG channel blocker? CC[C@H]1OC(=O)[C@H](C)[C@H](O[C@H]2C[C@](C)(OC)[C@H](O)[C@@H](C)O2)[C@@H](C)[C@@H](O[C@H]2O[C@H](C)C[C@@H]([NH+](C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@@]1(C)O
c50c3fa7-bb75-407a-9af6-7dd0de571d35
Yes
CCCOC(C(=O)OC1CCN(C)CC1)(c1ccccc1)c1ccccc1
Check whether the given drug blocks hERG channels. CCCOC(C(=O)OC1CCN(C)CC1)(c1ccccc1)c1ccccc1
fa591423-f813-4f0c-9122-46e221d21ef6
No
CCN(C)C(=O)Oc1cccc([C@H](C)[NH+](C)C)c1
Verify if this drug has hERG blocking properties. CCN(C)C(=O)Oc1cccc([C@H](C)[NH+](C)C)c1
c1744b10-3afb-4881-80ea-ccd07ae1b01c
No
CC(C)n1c(/C=C\[C@@H](O)C[C@@H](O)CC(=O)[O-])c(-c2ccc(F)cc2)c2ccccc21
Is this pharmaceutical compound a blocker of the hERG ion channel? CC(C)n1c(/C=C\[C@@H](O)C[C@@H](O)CC(=O)[O-])c(-c2ccc(F)cc2)c2ccccc21
79e7de0e-057a-46c6-8c7c-806818ade982
No
C/C=C1\N(C)[C@H](C)CC1(c1ccccc1)c1ccccc1
Does the specified drug exhibit hERG blocking activity? C/C=C1\N(C)[C@H](C)CC1(c1ccccc1)c1ccccc1
7017eac2-5f9c-47f0-910f-51592bb67d6d
Yes
Cc1nccn1C[C@@H]1CCc2c(c3ccccc3n2C)C1=O
Check whether the given drug blocks hERG channels. Cc1nccn1C[C@@H]1CCc2c(c3ccccc3n2C)C1=O
ee7bb8ac-bd4d-4d65-8cfd-eb7714d9f6f0
Yes
N#Cc1ccc(Cn2cncc2C[NH2+][C@@H]2CCN(C(=O)c3cccnc3[S-])C2=O)cc1
Is this pharmaceutical compound a blocker of the hERG ion channel? N#Cc1ccc(Cn2cncc2C[NH2+][C@@H]2CCN(C(=O)c3cccnc3[S-])C2=O)cc1
58eea172-3e77-47b7-a776-249dc35e0ac2
Yes
Oc1ccc(CC[NH+]2CCC(Nc3nc4ccccc4n3Cc3ccc(F)cc3)CC2)cc1
Does the drug listed below function as a hERG inhibitor? Oc1ccc(CC[NH+]2CCC(Nc3nc4ccccc4n3Cc3ccc(F)cc3)CC2)cc1
b5ac35a4-4179-4cd4-a12a-1f9c5b926f6e
Yes
Cc1ccc(-c2nc(NC(=O)CN3CCCN(C)CC3)cc(-n3nccc3C)n2)o1
Check whether the given drug blocks hERG channels. Cc1ccc(-c2nc(NC(=O)CN3CCCN(C)CC3)cc(-n3nccc3C)n2)o1
a18d47b0-40b9-4436-8a09-c6d02436d805
Yes
COc1ccc(CCO[C@@H]2CCCC[C@@H]2N2CC[C@@H](O)C2)cc1OC
Check whether the given drug blocks hERG channels. COc1ccc(CCO[C@@H]2CCCC[C@@H]2N2CC[C@@H](O)C2)cc1OC
7e2a98aa-1133-4cbc-ae52-0673ca1c0c7d
Yes
CC1=C(C/C=C(\C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)C(=O)c2ccccc2C1=O
Assess if the following substance is a hERG blocker. CC1=C(C/C=C(\C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)C(=O)c2ccccc2C1=O
2006a9fa-84df-4c46-9209-1695adf482c8
Yes
O=C(NC1CCN(Cc2ccc3c(c2)OCO3)CC1)c1cc(=O)c2ccc(F)cc2o1
Is the drug provided capable of blocking hERG channels? O=C(NC1CCN(Cc2ccc3c(c2)OCO3)CC1)c1cc(=O)c2ccc(F)cc2o1
b0f031f6-feaf-4ddb-8651-e0b6835d542a
Yes
Cc1cc2c(s1)=Nc1ccccc1NC=2N1CCNCC1
Does the specified drug exhibit hERG blocking activity? Cc1cc2c(s1)=Nc1ccccc1NC=2N1CCNCC1
d6d826a4-8eaf-4206-a17d-52b0f4a080bc
No
COc1ccc([C@@H]2CC(=O)c3c(O)cc(O)cc3O2)cc1O
Does the specified drug exhibit hERG blocking activity? COc1ccc([C@@H]2CC(=O)c3c(O)cc(O)cc3O2)cc1O
095e1c93-eb88-46dd-adae-ef9f607545ad
No
O=C1NCCN1CC[NH+]1CCC(c2cn(C3CCCCC3)c3ccc(Cl)cc23)CC1
Is the drug in question known to block hERG channels? O=C1NCCN1CC[NH+]1CCC(c2cn(C3CCCCC3)c3ccc(Cl)cc23)CC1
08b6c28c-9988-48d3-90fd-01a6935ff055
No
C#CC[NH+](C)[C@H](C)Cc1ccccc1
Assess if the following substance is a hERG blocker. C#CC[NH+](C)[C@H](C)Cc1ccccc1
fd6ff160-b0da-4d83-83ca-795e93f3f153
Yes
CC(C)(C)[C@H](O)C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1cccc(O)c1
Does this drug act as a hERG channel blocker? CC(C)(C)[C@H](O)C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1cccc(O)c1
0ebf3ead-ee85-45da-a31f-d6dfa3d5145c
No
CCCNC[C@@H](O)COc1ccc(O)cc1C(=O)CCc1ccccc1
Is the drug provided capable of blocking hERG channels? CCCNC[C@@H](O)COc1ccc(O)cc1C(=O)CCc1ccccc1
09aeae59-25b3-4c2b-8f04-5d9b05f0bd17
Yes
O=C1Cc2cc(CC[NH+]3CCN(c4nsc5ccccc45)CC3)c(Cl)cc2N1
Is the drug provided capable of blocking hERG channels? O=C1Cc2cc(CC[NH+]3CCN(c4nsc5ccccc45)CC3)c(Cl)cc2N1
7fe19f7f-fe64-4cdb-a99e-bd8846a2b7db
Yes
CCc1c(C)[nH]c2c1/C(=N/NC(=O)Nc1ccccc1)CCC2
Does the specified drug exhibit hERG blocking activity? CCc1c(C)[nH]c2c1/C(=N/NC(=O)Nc1ccccc1)CCC2
b8a3a675-a5d1-4f9c-a67f-78ec7b2e587f
Yes
O=C(CCCN1CCC(n2c(=O)[nH]c3ccccc32)CC1)c1ccc(F)cc1
Is this pharmaceutical compound a blocker of the hERG ion channel? O=C(CCCN1CCC(n2c(=O)[nH]c3ccccc32)CC1)c1ccc(F)cc1
ce4052ca-19e2-4528-b12b-4d6e83b9ad88
No
COc1ccc2cc3[n+](cc2c1OC)CCc1cc2c(cc1-3)OCO2
Verify if this drug has hERG blocking properties. COc1ccc2cc3[n+](cc2c1OC)CCc1cc2c(cc1-3)OCO2
65d67d17-19dd-4d9c-94fe-ba3ab5107f2d
No
NC(N)=NC[C@@H](N)C(=O)O
Does this drug act as a hERG channel blocker? NC(N)=NC[C@@H](N)C(=O)O
9758696f-05a7-4e8f-9099-855249cfc830
No
O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O.[Cu+2]
Verify if this drug has hERG blocking properties. O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O.[Cu+2]
a7511b3c-ac7b-4f84-8e52-7f9a6bb42a14
Yes
C[NH+]1CC[NH+](CCCCN2C(=O)CN(/N=C/c3ccc(-c4ccc(Cl)cc4)o3)C2=O)CC1
Check whether the given drug blocks hERG channels. C[NH+]1CC[NH+](CCCCN2C(=O)CN(/N=C/c3ccc(-c4ccc(Cl)cc4)o3)C2=O)CC1
d921df25-7adb-42c7-85c3-4994481aef11
Yes
CC(C)(C)c1ccc(C(=O)CCC[NH+]2CCC(OC(c3ccccc3)c3ccccc3)CC2)cc1
Determine if the following medication inhibits hERG potassium channels. CC(C)(C)c1ccc(C(=O)CCC[NH+]2CCC(OC(c3ccccc3)c3ccccc3)CC2)cc1
658d6e72-4402-4f66-8704-a8b499a0d938
Yes
N#Cc1ccc2c(=O)cc(C(=O)NC3CCN(Cc4ccc5c(c4)OCO5)CC3)oc2c1
Is the drug provided capable of blocking hERG channels? N#Cc1ccc2c(=O)cc(C(=O)NC3CCN(Cc4ccc5c(c4)OCO5)CC3)oc2c1
744f16dc-4808-402d-ba6e-7cba9d153736
Yes
CCOC(=O)C1=C[C@]2(CC)CCC[NH+]3CCc4c(n1c1ccccc41)[C@@H]32
Assess if the following substance is a hERG blocker. CCOC(=O)C1=C[C@]2(CC)CCC[NH+]3CCc4c(n1c1ccccc41)[C@@H]32
e893bb52-49bf-4292-9324-6cbb10b8a52c
Yes
Fc1ccc(-c2[nH]c3cc(F)ccc3c2[C@H]2CCC[NH2+]C2)cc1
Is the drug provided capable of blocking hERG channels? Fc1ccc(-c2[nH]c3cc(F)ccc3c2[C@H]2CCC[NH2+]C2)cc1
6f790c55-4e86-4504-ad7c-d5db0e2d537c
Yes
O=c1cc[nH+]c(NCC2CCN(c3nc4ccccc4n3Cc3ccc(F)cc3)CC2)[nH]1
Is the drug in question known to block hERG channels? O=c1cc[nH+]c(NCC2CCN(c3nc4ccccc4n3Cc3ccc(F)cc3)CC2)[nH]1
68ea0df6-3a64-4396-8666-9f5a742e192b
Yes
CCC(=O)C(C[C@@H](C)[NH+](C)C)(c1ccccc1)c1ccccc1
Does the drug listed below function as a hERG inhibitor? CCC(=O)C(C[C@@H](C)[NH+](C)C)(c1ccccc1)c1ccccc1