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RTA is one type of nephrotoxicity induced by FK506, and it is reversible in mild cases when appropriately treated.
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Deposits of plasma proteins in the skin during treatment with carbamazepine and diphenylhydantoin.
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The patient's asthma improved, and he remained asymptomatic; but routine study evaluations 9 to 12 months into therapy showed microhematuria, proteinuria, glucosuria, anemia, and renal insufficiency.
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At that time, the present researchers began to explore the development of a school-based, methodologically sound, and inexpensive method of assessing the efficacy of stimulant medications, which would ensure reasonable compliance by teachers, parents, and students in monitoring the effects of medications and placebos.
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CONCLUSIONS: The fundus picture shown in these cases may be typical of ASPPC after IVTA injection.
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Herpetic reactivation may occur in many forms after excimer laser ablation.
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Multiple foci of axonal degeneration and demyelination were found in the optic nerves and chiasm, the superficial layers of the brainstem, and spinal cord and to some extent in other cranial nerves and spinal nerve roots.
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Two days after the start of administration of SKT, her severe pain was markedly improved.
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Microsomal enzyme induction and clinical aggravation of porphyria: the evaluation of human urinary 6beta-hydroxycortisol/cortisol ratio as the index of hepatic CYP3A4 activity.
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A case is reported of myoclonus induced by an antidepressant purported to have no effect on serotonin activity.
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A 23-year-old Caucasian man diagnosed with stage IVB Hodgkin's disease was referred to a university oncology section after completing 1.5 cycles of chemotherapy.
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This case shows that radioinduced SMN can occurr with relatively low doses of RT (<50 Gy) and that it may occur very late.
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An urgent brain computed tomographic scan showed hemorrhage in the right cerebellum and subarachnoid region.
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Three patients who had experienced neuroleptic-induced akathisia in the past reported that the symptoms of fluoxetine-induced akathisia were identical, although somewhat milder.
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Administration of the drug for 8 days did not effectively shorten the recovery period compared with the average reported in the literature without the drug, and may have triggered additional iatrogenic complications.
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Late-developing but self-limiting neuropsychiatric complications occurred in four patients.
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A 74-year-old man received oral administration of pilsicainide, a pure sodium channel blocker with slow recovery kinetics, to convert paroxysmal atrial fibrillation to sinus rhythm and developed loss of consciousness two days later.
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Leflunomide, an immunosuppressive drug used in rheumatoid arthritis and in rejection in solid-organ transplantation, has been reported to have novel anti-CMV activity.
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Restless legs syndrome may thus be an adverse effect of IFN alpha treatment.
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Obstructive ileus is not common, but is a very distressing syndrome in a palliative care unit.
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The most likely cause of liver failure in this patient was, therefore, clarithromycin, which undergoes hepatic metabolism and has been reported to cause fulminant hepatic failure.
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A 61-year-old Japanese man with chronic myelogenous leukemia developed pityriasis lichenoides-like eruptions during chemotherapy.
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Within 48 hours after discontinuation of the medication, she had complete resolution of psychotic symptoms, fatigue, and psychomotor retardation, and her depression improved.
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Physicians must be aware that the public is still ingesting the drug and remain rigorous in including its toxicity in the differential diagnosis of acute neurologic events.
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Clearance rates of cerivastatin metabolites in a patient with cerivastatin-induced rhabdomyolysis.
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The possible mechanism is thought to be an allergic reaction to the drug.
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Eighty-four percent of patients reported an increase in their sense of well-being.
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We found that positive biopsies are usual only if the duration of symptoms have been allowed to persist for more than 6 months.
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Red blood cell anemia in a patient with pemphigus vulgaris induced by the use of mycophenolate mofetil and prednisone.
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CASE REPORT: A 68-year-old woman experienced a severe febrile reaction after a plateletpheresis transfusion.
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Visceral leishmaniasis and macrophagic activation syndrome in a patient with rheumatoid arthritis under treatment with adalimumab.
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MR findings in methotrexate-induced CNS abnormalities.
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BACKGROUND: Many patients receiving long-term total parenteral nutrition (TPN) develop liver disease; cholestasis is common and may be severe.
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The fingernails were more affected than the toenails and clinically the changes consisted of absence of lunulae, longitudinal ridging, transverse or longitudinal defects of the nailplate and a tendency of onychoschizia.
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We report that these tumors frequently express the CD-20 antigen, and immunotherapy directed at this antigen may be a well-tolerated and effective treatment.
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After receiving conventional chemotherapy, they underwent multicyclic DI-CT consisting of CDDP, ETP and ifosfamide supported by G-CSF and ABPCT.
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Combined data reveal that 12 of 23 have had a complete or partial response with residual thrombocytopenia and a probability of 48% survival one year from the start of ATG therapy as projected by life table analysis.
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CONCLUSIONS: Amantadine can cause reversible corneal edema but can irreversibly reduce the density of endothelial cells.
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Herpes simplex epithelial keratitis developed in four renal transplant recipients while they were receiving high-dose systemic corticosteroid and immunosuppressive therapy.
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The most common hematologic SMNs are myelodysplasia (MDS) and acute myelogenous leukemia (AML).
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Further surveillance and caution are suggested in patients with known coronary artery disease or atrial dysrhythmia.
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She was receiving chronic therapeutic doses of HCQ for the treatment of lupus erythematosus.
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Five patients experienced increased intraocular pressure to 30 mmHg or greater which required treatment.
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Drug-induced hepatitis in an acromegalic patient during combined treatment with pegvisomant and octreotide long-acting repeatable attributed to the use of pegvisomant.
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With the increasing use of chemotherapy for many different primary malignancies, secondary or therapy-related acute myeloid leukaemias (AML) and myelodysplastic syndromes (MDS) are becoming more common.
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Dosage varied widely, but as little as 0.1 mg caused significant signs and symptoms.
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Alcohol neurolysis for persistent pain caused by superior cluneal nerves injury after iliac crest bone graft harvesting in orthopedic surgery: report of four cases and review of the literature.
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This report addresses the issue of whether linear IgA bullous dermatosis can be associated with gluten-sensitive enteropathy.
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The patient became cyanotic with a PaO2 of 39 mmHg.
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These preliminary results indicate the possible advantage of adding an alkylating agent (prednimustine) to estramustine in advanced prostatic carcinoma.
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Clinicians should be aware to this complication.
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Cholelithiasis and thrombosis of the central retinal vein in a renal transplant recipient treated with cyclosporin.
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Blood cultures were negative.
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The case report discussed is, to our knowledge, the third of its kind regarding bone fluorosis resulting from use of this nicotinic derivative.
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Ovarian hyperstimulation syndrome (OHSS) is a serious complication of assisted reproduction techniques using in vitro fertilization and intracytoplasmic sperm injection (IVF/ICSI).
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Nitrofurantoin, one of the antimicrobial agents which should be chosen for the prophylactic treatment of recurrent urinary tract infection, may be prescribed in the conventional form or, alternatively, as macrocrystals.
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The risk of infections and growth suppression is minimized by using small maintenance dosage and alternate day therapy.
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The patient had also been taking concomitant allopurinol and captopril for more than 4 years with no complications, and valproic acid 3 months before the cutaneous event.
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The patient who survived had been taking the lowest dose of azathioprine and was given the recommended dose of acyclovir.
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The clinical course suggests that caffeine, which is present in oolong tea, was mainly responsible for the rhabdomyolysis as well as the delirium, although severe hyponatremia has been reported to cause rhabdomyolysis on rare occasions.
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Opioid drugs cause biliary sphincter spasm.
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Attention must be paid to this complication because the outcome and functional prognosis are better when pulmonary involvement is gold related: in our case steroid therapy was life-saving and induced complete recovery of the lung damage.
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A lymphocyte stimulation test was reactive to pranlukast.
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We report the case of a 17-year-old male who developed chest pain, elevated cardiac biomarkers, and acute left ventricular dysfunction following a single dose of methylphenidate.
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Although the incidence of antimalarial psychosis is unclear and perhaps small, we recommend close observation of patients for behavioral changes suggesting the development of antimalarial psychosis.
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The most common side effects associated with amifostine are nausea, vomiting, hypotension, hypocalcemia and allergic reactions.
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There are several side effects that it is commonly associated with; however, it has only rarely been reported to cause lung injury.
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In general, angiotensin converting enzyme (ACE) inhibitors should be discontinued in pregnancy, as they can induce an ACE fetopathy.
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We report the first case of fulminant hepatic failure associated with its use.
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On 26 April 1999, three persons were accidentally exposed by high dose (60)Co irradiation.
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It is generally hypothesized to be due to a point mutation in the androgen receptor that allows the antiandrogen to function as an agonist, leading to a dramatic and rapid PSA response.
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He rapidly recovered by intravenous hydrocortisone followed by oral prednisone administrations and percutaneous catheter pericardial drainage.
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Combination chemotherapy for bone marrow relapse in childhood lymphoblastic leukaemia (ALL).
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Because new drug therapies have been developed, it is important to know the interactions between antiretroviral and antiepileptic agents.
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Basilar invagination and mid-line skeletal abnormalities due to in utero exposure to phenytoin.
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Hyperkalemia as a late side effect of prolonged adrenocorticotropic hormone therapy for infantile spasms.
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The authors present a case report of a pregnant woman with persistent left adnexal mass and subsequently found to have a primary endodermal sinus tumor of the ovary that was diagnosed at 19 weeks of gestation.
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Rapamycin/sirolimus (SR), trade named Rapammune (Wyeth-Ayerst, Sydney, Australia), is a potent immunosuppressive drug associated with myelosuppression, hypertension, hyperlipidemia, and infection.
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The implications are stressed in relation to the differential diagnosis of patients with gastroenterological disorders who develop peripheral neuropathy.
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However, deterioration of his clinical state indicated LT.
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We report three cases of amiodarone-induced torsades de pointe.
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A report of two cases and review of the literature.
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It generally results in painless bleeding or abdominal pain.
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She was treated with high dosage corticosteroids and incurred severe side effects, including bone marrow depression, renal magnesium stones, osteoporosis, depression of affect, convulsions with cerebral damage and adrenal suppression.
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The clinical picture was identical to that of chloroquine and hydroxychloroquine maculopathy.
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Gold-salt therapy may result in damage to proximal tubules that leak renal tubular antigens, which in turn complex with autoantibody and produce an autoimmune membranous nephropathy.
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Protamine is used widely to reverse the anticoagulant effects of heparin and to delay the absorption of insulin.
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Acute psychosis associated with levetiracetam.
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Difficulty with anticoagulation may still be experienced with the newer formulations.
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Pituitary tumor made symptomatic during hormone therapy and induced pregnancy.
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Five weeks after the diagnosis of systemic candidiasis, sudden anuria developed, and ultrasonography showed echogenic material in both renal pelvises.
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We review the existing literature on AHS pathogenesis and illustrate a case complicated by liver dysfunction where the use of N-acetylcysteine (N-AC) and intravenous immunoglobulin (IVIG) may have altered the course of the disease.
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The clinical course and histological findings are presented.
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In two of these cases, it was sufficiently marked for the course of treatment to be curtailed and occurred at a relatively low cumulative dose of the drug.
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However, an increasing number of case reports and clinical studies on thrombolysis during and after CPR highlight an increased frequency of the return of spontaneous circulation and a better neurological outcome of surviving patients.
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According to our case report and to the literature, the onset of acute dyspnea after chemotherapy for lung metastatic germ cell tumor should alert to the possibility of spontaneous pneumothorax.
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On January 22, laboratory tests showed normal values of CK, CK-MB, and myoglobin.
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The patient subsequently underwent surgery for embolization of the right occipital and superficial temporal arteries and removal of the mass.
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PURPOSE: The aim of this study was to discuss the potential implications of prolonged and aggressive treatment of long-term survivors of ovarian cancer.
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Improved awareness and rapid treatment of the second patient had a favorable outcome with no sequelae.
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