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4
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15.5
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234 values
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stringlengths
3
243
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stringclasses
1 value
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stringlengths
332
1.37k
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stringclasses
2 values
prompt_strategy
stringclasses
1 value
t1_8859
task1
7.4432
Cucurbit[7]uril
(+)-fenchone
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule (+)-fenchone (SMILES: CC1(C2CCC(C2)(C1=O)C)C) in aqueous solution at standard conditions. Provide a single numeric...
cb7_supplement
base
t1_2558
task1
6.7993
Cucurbit[7]uril
1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole (SMILES: C12C=CC3(O2)CNCC3C1) in aqueous solution at standard condition...
cb7_supplement
base
t1_5419
task1
4.5991
Cucurbit[7]uril
Melamine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Melamine (SMILES: Nc1nc(N)nc(n1)N) in aqueous solution at standard conditions. Provide a single numerical value. ...
cb7_supplement
base
t1_8647
task1
7.1335
Cucurbit[7]uril
pentacyclo[7.3.1.14,12.02,7.06,11]tetradecane-4,9-diol
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule pentacyclo[7.3.1.14,12.02,7.06,11]tetradecane-4,9-diol (SMILES: C1C2C3CC4(CC2C5CC1(CC3C5C4)O)O) in aqueous solutio...
cb7_supplement
base
t1_7089
task1
3.1461
Cucurbit[7]uril
Calcium cation
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Calcium cation (SMILES: [Ca+2]) in aqueous solution at standard conditions. Provide a single numerical value. Put...
cb7_supplement
base
t1_8263
task1
5.8976
Cucurbit[7]uril
butane-1,4-diamine;dihydrochloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule butane-1,4-diamine;dihydrochloride (SMILES: C(CCN)CN.Cl.Cl) in aqueous solution at standard conditions. Provide a ...
cb7_supplement
base
t1_2580
task1
5.3617
Cucurbit[7]uril
N-(furan-2-ylmethyl)propan-1-amine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule N-(furan-2-ylmethyl)propan-1-amine (SMILES: CCCNCC1=CC=CO1) in aqueous solution at standard conditions. Provide a ...
cb7_supplement
base
t1_8851
task1
6.2504
Cucurbit[7]uril
beta-Estradiol
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule beta-Estradiol (SMILES: CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O) in aqueous solution at standard conditions. Provide a...
cb7_supplement
base
t1_4945
task1
3.2304
Cucurbit[7]uril
Pyrrole
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Pyrrole (SMILES: C1=CNC=C1) in aqueous solution at standard conditions. Provide a single numerical value. Put you...
cb7_supplement
base
t1_5152
task1
8.5048
Cucurbit[7]uril
Pentane-1,5-diamine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Pentane-1,5-diamine (SMILES: C(CCN)CCN) in aqueous solution at standard conditions. Provide a single numerical val...
cb7_supplement
base
t1_8381
task1
7.301
Cucurbit[7]uril
1-hexyl-3-methylimidazol-3-ium;chloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1-hexyl-3-methylimidazol-3-ium;chloride (SMILES: CCCCCCN1C=C[N+](=C1)C.[Cl-]) in aqueous solution at standard cond...
cb7_supplement
base
t1_7071
task1
6.5085
Cucurbit[7]uril
Decyltrimethylammonium bromide
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Decyltrimethylammonium bromide (SMILES: CCCCCCCCCC[N+](C)(C)C.[Br-]) in aqueous solution at standard conditions. P...
cb7_supplement
base
t1_8880
task1
7.2798
Cucurbit[7]uril
Cyclohexanone
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Cyclohexanone (SMILES: C1CCC(=O)CC1) in aqueous solution at standard conditions. Provide a single numerical value....
cb7_supplement
base
t1_42
task1
5.6721
Cucurbit[7]uril
Vecuronium
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Vecuronium (SMILES: CC(=O)OC1CC2CCC3C(C2(CC1N4CCCCC4)C)CCC5(C3CC(C5OC(=O)C)[N+]6(CCCCC6)C)C) in aqueous solution a...
cb7_supplement
base
t1_6266
task1
4.6184
Cucurbit[7]uril
Thr-Gly-D-Ala-Phe-Met-NH2
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Thr-Gly-D-Ala-Phe-Met-NH2 (SMILES: CSCC[C@@H](C(=O)N)NC(=O)[C@@H](NC(=O)[C@H](NC(=O)CNC(=O)C([C@H](O)C)N)C)Cc1cccc...
cb7_supplement
base
t1_8271
task1
8.1461
Cucurbit[7]uril
pentane-1,5-diamine dihydrochloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule pentane-1,5-diamine dihydrochloride (SMILES: C(CCN)CCN.Cl.Cl) in aqueous solution at standard conditions. Provide ...
cb7_supplement
base
t1_2564
task1
6.4624
Cucurbit[7]uril
6-bromo-1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 6-bromo-1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole (SMILES: BrC12C=CC3(O2)CNCC3C1) in aqueous solution at standard...
cb7_supplement
base
t1_7068
task1
6.5818
Cucurbit[7]uril
Cetrimonium bromide
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Cetrimonium bromide (SMILES: CCCCCCCCCCCCCCCC[N+](C)(C)C.[Br-]) in aqueous solution at standard conditions. Provid...
cb7_supplement
base
t1_4059
task1
3.375
Cucurbit[7]uril
Potassium chloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Potassium chloride (SMILES: [Cl-].[K+]) in aqueous solution at standard conditions. Provide a single numerical val...
cb7_supplement
base
t1_8881
task1
8.1825
Cucurbit[7]uril
bicyclo[2.2.1]heptan-2-one
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule bicyclo[2.2.1]heptan-2-one (SMILES: C1CC2CC1CC2=O) in aqueous solution at standard conditions. Provide a single nu...
cb7_supplement
base
t1_2301
task1
15.5002
Cucurbit[7]uril
bis(Trimethylamminomethyl)ferrocene
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule bis(Trimethylamminomethyl)ferrocene (SMILES: C[N+](C)(Cc1cccc1)C.C[N+](C)(Cc2cccc2)C.[Fe]) in aqueous solution at ...
cb7_supplement
base
t1_6640
task1
4.8351
Cucurbit[7]uril
Serotonin
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Serotonin (SMILES: C1=CC2=C(C=C1O)C(=CN2)CCN) in aqueous solution at standard conditions. Provide a single numeric...
cb7_supplement
base
t1_6115
task1
6.1761
Cucurbit[7]uril
Recombinant insulin human
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Recombinant insulin human (SMILES: CCC(C)C1C(=O)NC2CSSCC(C(=O)NC(CSSCC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O...
cb7_supplement
base
t1_4092
task1
3.505
Cucurbit[7]uril
Cesium chloride, Caesium chloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Cesium chloride, Caesium chloride (SMILES: [Cl-].[Cs+]) in aqueous solution at standard conditions. Provide a sing...
cb7_supplement
base
t1_2017
task1
6.42
Cucurbit[7]uril
1-methyl-3-[[4-[(3-methylimidazol-3-ium-1-yl)methyl]phenyl]methyl]imidazol-1-ium
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1-methyl-3-[[4-[(3-methylimidazol-3-ium-1-yl)methyl]phenyl]methyl]imidazol-1-ium (SMILES: C[N+]1=CN(C=C1)CC2=CC=C(...
cb7_supplement
base
t1_8422
task1
9.3222
Cucurbit[7]uril
Hexamethylenediamine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Hexamethylenediamine (SMILES: C(CCCN)CCN) in aqueous solution at standard conditions. Provide a single numerical v...
cb7_supplement
base
t1_2021
task1
6.7251
Cucurbit[7]uril
1-methyl-3-[[6-[(3-methylimidazol-3-ium-1-yl)methyl]naphthalen-2-yl]methyl]imidazol-1-ium
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1-methyl-3-[[6-[(3-methylimidazol-3-ium-1-yl)methyl]naphthalen-2-yl]methyl]imidazol-1-ium (SMILES: C[N+]1=CN(C=C1)...
cb7_supplement
base
t1_8310
task1
3.3743
Cucurbit[7]uril
Dehydrocorydaline
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Dehydrocorydaline (SMILES: CC1=C2C=CC(=C(C2=C[N+]3=C1C4=CC(=C(C=C4CC3)OC)OC)OC)OC) in aqueous solution at standard...
cb7_supplement
base
t1_2573
task1
6.0414
Cucurbit[7]uril
N-((5-methylfuran-2-yl)methyl)prop-2-en-1-amine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule N-((5-methylfuran-2-yl)methyl)prop-2-en-1-amine (SMILES: C=CCNCC1=CC=C(C)O1) in aqueous solution at standard condi...
cb7_supplement
base
t1_5770
task1
8.699
Cucurbit[7]uril
Coptisine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Coptisine (SMILES: C1C[N+]2=C(C=C3C=CC4=C(C3=C2)OCO4)C5=CC6=C(C=C51)OCO6) in aqueous solution at standard conditio...
cb7_supplement
base
t1_7286
task1
2.301
Cucurbit[7]uril
Glycyltyrosine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Glycyltyrosine (SMILES: C1=CC(=CC=C1CC(C(=O)O)NC(=O)CN)O) in aqueous solution at standard conditions. Provide a si...
cb7_supplement
base
t1_6281
task1
8.7243
Cucurbit[7]uril
((S)-2-amino-3-(4-(aminomethyl)phenyl)propanoyl)-L-methionine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule ((S)-2-amino-3-(4-(aminomethyl)phenyl)propanoyl)-L-methionine (SMILES: NCc1ccc(cc1)C[C@@H](C(=O)N[C@H](C(=O)O)CCSC...
cb7_supplement
base
t1_8849
task1
5.9101
Cucurbit[7]uril
Cholesterol
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Cholesterol (SMILES: CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C) in aqueous solution at standard conditions. ...
cb7_supplement
base
t1_7090
task1
1.6232
Cucurbit[7]uril
Magnesium cation
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Magnesium cation (SMILES: [Mg+2]) in aqueous solution at standard conditions. Provide a single numerical value. P...
cb7_supplement
base
t1_8618
task1
8.9705
Cucurbit[7]uril
2,7-dimethyldiazapyrenium
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 2,7-dimethyldiazapyrenium (SMILES: C[N+]1=CC2=C3C4=C(C=[N+](C)C=C4C=CC3=C1)C=C2) in aqueous solution at standard c...
cb7_supplement
base
t1_4968
task1
2.7848
Cucurbit[7]uril
Acetone
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Acetone (SMILES: CC(=O)C) in aqueous solution at standard conditions. Provide a single numerical value. Put your ...
cb7_supplement
base
t1_7091
task1
2.3424
Cucurbit[7]uril
Zinc cation
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Zinc cation (SMILES: [Zn+2]) in aqueous solution at standard conditions. Provide a single numerical value. Put yo...
cb7_supplement
base
t1_2897
task1
8.415
Cucurbit[7]uril
Borneol
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Borneol (SMILES: CC1(C2CCC1(C(C2)O)C)C) in aqueous solution at standard conditions. Provide a single numerical val...
cb7_supplement
base
t1_8785
task1
3.9031
Cucurbit[7]uril
AntNMe2+-2kPEG-OMe
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule AntNMe2+-2kPEG-OMe (SMILES: COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO...
cb7_supplement
base
t1_1837
task1
15.0792
Cucurbit[7]uril
N1,N1'-(bicyclo[2.2.2]octane-1,4-diylbis(methylene))bis(N3,N3-dimethylpropane-1,3-diamine)
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule N1,N1'-(bicyclo[2.2.2]octane-1,4-diylbis(methylene))bis(N3,N3-dimethylpropane-1,3-diamine) (SMILES: CN(C)CCCNCC12C...
cb7_supplement
base
t1_8425
task1
9.4238
Cucurbit[7]uril
1-(hydroxymethyl)-ferrocene
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1-(hydroxymethyl)-ferrocene (SMILES: [CH]1[CH][CH][CH][CH]1.[CH]1[CH][CH][C]([CH]1)CO.[Fe]) in aqueous solution at...
cb7_supplement
base
t1_3288
task1
2.9395
Cucurbit[7]uril
D/L-lysine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule D/L-lysine (SMILES: C(CCN)CC(C(=O)O)N) in aqueous solution at standard conditions. Provide a single numerical valu...
cb7_supplement
base
t1_8379
task1
6.8808
Cucurbit[7]uril
1-butyl-3-methylimidazolium hexafluorophosphate
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1-butyl-3-methylimidazolium hexafluorophosphate (SMILES: CCCCN1C=C[N+](=C1)C.F[P-](F)(F)(F)(F)F) in aqueous soluti...
cb7_supplement
base
t1_6116
task1
6.4782
Cucurbit[7]uril
Phe-Gly-Gly
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Phe-Gly-Gly (SMILES: C1=CC=C(C=C1)CC(C(=O)NCC(=O)NCC(=O)O)N) in aqueous solution at standard conditions. Provide a...
cb7_supplement
base
t1_1948
task1
4.8681
Cucurbit[7]uril
2,7-bis(2-(trimethyl-azaneyl)ethyl)pyrene-1,3,6,8(2H,7H)-tetraone
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 2,7-bis(2-(trimethyl-azaneyl)ethyl)pyrene-1,3,6,8(2H,7H)-tetraone (SMILES: O=C(C(CC[N+](C)(C)C)C1=O)C2=CC=C3C4=C2C...
cb7_supplement
base
t1_4971
task1
3.8287
Cucurbit[7]uril
Pinacolone
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Pinacolone (SMILES: CC(=O)C(C)(C)C) in aqueous solution at standard conditions. Provide a single numerical value. ...
cb7_supplement
base
t1_2035
task1
7.8451
Cucurbit[7]uril
bis(dimethylpyridinium)diarylethene (closed form)
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule bis(dimethylpyridinium)diarylethene (closed form) (SMILES: C[C@@]12C(C=C(C3=CC=[N+](C)C=C3)S2)=C4C(CCC4)=C5[C@@]1(...
cb7_supplement
base
t1_5765
task1
3.0792
Cucurbit[7]uril
L-Tryptophan
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule L-Tryptophan (SMILES: C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)N) in aqueous solution at standard conditions. Provide a sing...
cb7_supplement
base
t1_6367
task1
9.0212
Cucurbit[7]uril
AM Phe-Gly-Gly
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule AM Phe-Gly-Gly (SMILES: NCc1ccc(cc1)C[C@@H](C(=O)NCC(=O)NCC(=O)O)N) in aqueous solution at standard conditions. Pr...
cb7_supplement
base
t1_8424
task1
14
Cucurbit[7]uril
2-Adamantylamine hydrochloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 2-Adamantylamine hydrochloride (SMILES: C1C2CC3CC1CC(C2)C3N.Cl) in aqueous solution at standard conditions. Provid...
cb7_supplement
base
t1_5500
task1
5.301
Cucurbit[7]uril
1,1'-bis(5-carboxypentyl)-[4,4'-bipyridine]-1,1'-diium
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1,1'-bis(5-carboxypentyl)-[4,4'-bipyridine]-1,1'-diium (SMILES: OC(=O)CCCCC[n+]1ccc(cc1)c1cc[n+](cc1)CCCCCC(=O)O) ...
cb7_supplement
base
t1_4994
task1
3.0086
Cucurbit[7]uril
Methyl acetate
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Methyl acetate (SMILES: COC(=O)C) in aqueous solution at standard conditions. Provide a single numerical value. P...
cb7_supplement
base
t1_8232
task1
2.5378
Cucurbit[7]uril
Diquat
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Diquat (SMILES: C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31) in aqueous solution at standard conditions. Provide a single num...
cb7_supplement
base
t1_6275
task1
3.2826
Cucurbit[7]uril
Phosphoramidon
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Phosphoramidon (SMILES: CC1C(C(C(C(O1)OP(=O)(NC(CC(C)C)C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)O)O)O)O)O) in aqueous solut...
cb7_supplement
base
t1_2883
task1
5.9294
Cucurbit[7]uril
Eucalyptol
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Eucalyptol (SMILES: CC1(C2CCC(O1)(CC2)C)C) in aqueous solution at standard conditions. Provide a single numerical ...
cb7_supplement
base
t1_4970
task1
3.3139
Cucurbit[7]uril
3-Pentanone
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 3-Pentanone (SMILES: CCC(=O)CC) in aqueous solution at standard conditions. Provide a single numerical value. Put...
cb7_supplement
base
t1_8392
task1
5
Cucurbit[7]uril
Dopamine hydrochloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Dopamine hydrochloride (SMILES: C1=CC(=C(C=C1CCN)O)O.Cl) in aqueous solution at standard conditions. Provide a sin...
cb7_supplement
base
t1_6265
task1
4.3173
Cucurbit[7]uril
Thr-Gly-Ala-Phe-Met-NH2
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Thr-Gly-Ala-Phe-Met-NH2 (SMILES: CSCC[C@@H](C(=O)N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)C([C@H](O)C)N)C)Cc1ccccc...
cb7_supplement
base
t1_7146
task1
9.1614
Cucurbit[7]uril
Pibenzimol HCl
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Pibenzimol HCl (SMILES: CN1CCN(CC1)C2=CC3=C(C=C2)N=C(N3)C4=CC5=C(C=C4)N=C(N5)C6=CC=C(C=C6)O.Cl.Cl.Cl) in aqueous s...
cb7_supplement
base
t1_591
task1
7.301
Cucurbit[7]uril
Proflavine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Proflavine (SMILES: C1=CC(=CC2=NC3=C(C=CC(=C3)N)C=C21)N) in aqueous solution at standard conditions. Provide a sin...
cb7_supplement
base
t1_8663
task1
5.7756
Cucurbit[7]uril
1-Hexanol
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1-Hexanol (SMILES: CCCCCCO) in aqueous solution at standard conditions. Provide a single numerical value. Put you...
cb7_supplement
base
t1_8269
task1
3.8195
Cucurbit[7]uril
Tetramethyl benzobis (imidazolium)
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Tetramethyl benzobis (imidazolium) (SMILES: C[N+]1=CN(C)C2=CC([N+](C)=CN3C)=C3C=C21) in aqueous solution at standa...
cb7_supplement
base
t1_2895
task1
6.6812
Cucurbit[7]uril
Fenchol
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Fenchol (SMILES: CC1(C2CCC(C2)(C1O)C)C) in aqueous solution at standard conditions. Provide a single numerical val...
cb7_supplement
base
t1_4110
task1
2.8202
Cucurbit[7]uril
Ammonium chloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Ammonium chloride (SMILES: [NH4+].[Cl-]) in aqueous solution at standard conditions. Provide a single numerical va...
cb7_supplement
base
t1_8372
task1
4.8751
Cucurbit[7]uril
1,3-Dimethylimidazolium
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1,3-Dimethylimidazolium (SMILES: CN1C=C[N+](=C1)C) in aqueous solution at standard conditions. Provide a single nu...
cb7_supplement
base
t1_6431
task1
6
Cucurbit[7]uril
Ferrocene
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Ferrocene (SMILES: [CH-]1C=CC=C1.[CH-]1C=CC=C1.[Fe+2]) in aqueous solution at standard conditions. Provide a singl...
cb7_supplement
base
t1_2561
task1
6
Cucurbit[7]uril
N-((5-bromofuran-2-yl)methyl)prop-2-en-1-amine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule N-((5-bromofuran-2-yl)methyl)prop-2-en-1-amine (SMILES: C=CCNCC1=CC=C(Br)O1) in aqueous solution at standard condi...
cb7_supplement
base
t1_5459
task1
5.3617
Cucurbit[7]uril
Oxaliplatin
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Oxaliplatin (SMILES: C1CCC(C(C1)[NH-])[NH-].C(=O)(C(=O)[O-])[O-].[Pt+4]) in aqueous solution at standard condition...
cb7_supplement
base
t1_4113
task1
3.54
Cucurbit[7]uril
Silver chloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Silver chloride (SMILES: Cl[Ag]) in aqueous solution at standard conditions. Provide a single numerical value. Pu...
cb7_supplement
base
t1_2570
task1
6.7993
Cucurbit[7]uril
6-chloro-1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 6-chloro-1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole (SMILES: ClC12C=CC3(O2)CNCC3C1) in aqueous solution at standar...
cb7_supplement
base
t1_7899
task1
7.1461
Cucurbit[7]uril
H-Phe-Met-OH
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule H-Phe-Met-OH (SMILES: CSCCC(C(=O)O)NC(=O)C(CC1=CC=CC=C1)N) in aqueous solution at standard conditions. Provide a s...
cb7_supplement
base
t1_4131
task1
4.179
Cucurbit[7]uril
Iron(III) chloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Iron(III) chloride (SMILES: Cl[Fe](Cl)Cl) in aqueous solution at standard conditions. Provide a single numerical v...
cb7_supplement
base
t1_594
task1
5.301
Cucurbit[7]uril
Acridine Orange hydrochloride (protonated)
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Acridine Orange hydrochloride (protonated) (SMILES: CN(C)C1=CC2=C(C=C1)C=C3C=CC(=CC3=N2)N(C)C.Cl) in aqueous solut...
cb7_supplement
base
t1_1842
task1
14.2304
Cucurbit[7]uril
1-Adamantylazanium
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1-Adamantylazanium (SMILES: C1C2CC3CC1CC(C2)(C3)[NH3+]) in aqueous solution at standard conditions. Provide a sing...
cb7_supplement
base
t1_4137
task1
4.9873
Cucurbit[7]uril
Lanthanum chloride heptahydrate
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Lanthanum chloride heptahydrate (SMILES: O.O.O.O.O.O.O.[Cl-].[Cl-].[Cl-].[La+3]) in aqueous solution at standard c...
cb7_supplement
base
t1_5399
task1
12
Cucurbit[7]uril
N-Butyladamantan-1-aminium
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule N-Butyladamantan-1-aminium (SMILES: CCCC[NH2+]C12C[C@@H]3C[C@H](C2)C[C@H](C1)C3) in aqueous solution at standard c...
cb7_supplement
base
t1_4973
task1
3.6628
Cucurbit[7]uril
1-Phenyl-2-butanone
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1-Phenyl-2-butanone (SMILES: CCC(=O)Cc1ccccc1) in aqueous solution at standard conditions. Provide a single numeri...
cb7_supplement
base
t1_5530
task1
3.4472
Cucurbit[7]uril
[Ru(bpy)2dppz]2+
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule [Ru(bpy)2dppz]2+ (SMILES: C1=CC=C2C(=C1)N=C3C4=C(C5=C(C3=N2)C=CC=N5)N=CC=C4.C1=CC=NC(=C1)C2=CC=CC=N2.C1=CC=NC(=C1)...
cb7_supplement
base
t1_7088
task1
2.7634
Cucurbit[7]uril
Rubidium cation
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Rubidium cation (SMILES: [Rb+]) in aqueous solution at standard conditions. Provide a single numerical value. Put...
cb7_supplement
base
t1_6638
task1
5.6684
Cucurbit[7]uril
Dopamine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Dopamine (SMILES: C1=CC(=C(C=C1CCN)O)O) in aqueous solution at standard conditions. Provide a single numerical val...
cb7_supplement
base
t1_632
task1
5.3546
Cucurbit[7]uril
Rhodamine B
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Rhodamine B (SMILES: CCN(CC)C1=CC2=C(C=C1)C(=C3C=CC(=[N+](CC)CC)C=C3O2)C4=CC=CC=C4C(=O)O.[Cl-]) in aqueous solutio...
cb7_supplement
base
t1_8664
task1
6.0969
Cucurbit[7]uril
(Z)‐4‐(4‐(2‐(3′,5′‐bis(trifluoromethyl)‐[1,1′‐biphenyl]‐4‐yl)‐1‐cyanovinyl)phenyl)‐1‐methylpyridin‐1‐ium chloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule (Z)‐4‐(4‐(2‐(3′,5′‐bis(trifluoromethyl)‐[1,1′‐biphenyl]‐4‐yl)‐1‐cyanovinyl)phenyl)‐1‐methylpyridin‐1‐ium chloride ...
cb7_supplement
base
t1_1828
task1
3.9685
Cucurbit[7]uril
7,8-dimethyl-1H-benzo[g]pteridine-2,4-dione
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 7,8-dimethyl-1H-benzo[g]pteridine-2,4-dione (SMILES: CC1=CC2=C(C=C1C)N=C3C(=N2)C(=O)NC(=O)N3) in aqueous solution ...
cb7_supplement
base
t1_4125
task1
3.4
Cucurbit[7]uril
Zinc chloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Zinc chloride (SMILES: Cl[Zn]Cl) in aqueous solution at standard conditions. Provide a single numerical value. Pu...
cb7_supplement
base
t1_5400
task1
8.3617
Cucurbit[7]uril
(1R,4R)-cyclohexane-1,4-diamine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule (1R,4R)-cyclohexane-1,4-diamine (SMILES: C1CC(CCC1N)N) in aqueous solution at standard conditions. Provide a singl...
cb7_supplement
base
t1_1927
task1
7.0414
Cucurbit[7]uril
[Amino-[4-[6-[amino(azaniumylidene)methyl]-1H-indol-2-yl]phenyl]methylidene]azanium
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule [Amino-[4-[6-[amino(azaniumylidene)methyl]-1H-indol-2-yl]phenyl]methylidene]azanium (SMILES: C1=CC(=CC=C1C2=CC3=C(...
cb7_supplement
base
t1_5524
task1
5.4472
Cucurbit[7]uril
Thiazole orange
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Thiazole orange (SMILES: CC1=CC=C(C=C1)S(=O)(=O)[O-].CN1C2=CC=CC=C2SC1=CC3=CC=[N+](C4=CC=CC=C34)C) in aqueous solu...
cb7_supplement
base
t1_4134
task1
4.42
Cucurbit[7]uril
Ytterbium(III) chloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Ytterbium(III) chloride (SMILES: Cl[Yb](Cl)Cl) in aqueous solution at standard conditions. Provide a single numeri...
cb7_supplement
base
t1_5550
task1
3
Cucurbit[7]uril
Rhodamine methylester chloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Rhodamine methylester chloride (SMILES: COC(=O)C1=CC=CC=C1C2=C3C=CC(=N)C=C3OC4=C2C=CC(=C4)N.Cl) in aqueous solutio...
cb7_supplement
base
t1_8285
task1
5.6021
Cucurbit[7]uril
(2S)-2-amino-3-phenylpropanoic acidhydrochloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule (2S)-2-amino-3-phenylpropanoic acidhydrochloride (SMILES: C1=CC=C(C=C1)CC(C(=O)O)N.Cl) in aqueous solution at stan...
cb7_supplement
base
t1_51
task1
5.7709
Cucurbit[7]uril
Pancuronium
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Pancuronium (SMILES: CC(=O)OC1CC2CCC3C(C2(CC1[N+]4(CCCCC4)C)C)CCC5(C3CC(C5OC(=O)C)[N+]6(CCCCC6)C)C) in aqueous sol...
cb7_supplement
base
t1_4107
task1
3.4099
Cucurbit[7]uril
Sodium chloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Sodium chloride (SMILES: [Na+].[Cl-]) in aqueous solution at standard conditions. Provide a single numerical value...
cb7_supplement
base
t1_7082
task1
4.741
Cucurbit[7]uril
Tetrakis(pyridin-4-ylsulfanyl)-phthalocyaninato zinc(II)
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Tetrakis(pyridin-4-ylsulfanyl)-phthalocyaninato zinc(II) (SMILES: C[N+](C=C1)=CC=C1SC2=CC(C(C=C2)=C3N=C(C4=C5C=CC(...
cb7_supplement
base
t1_8914
task1
4.3911
Cucurbit[7]uril
Aluminum cation
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Aluminum cation (SMILES: [Al+3]) in aqueous solution at standard conditions. Provide a single numerical value. Pu...
cb7_supplement
base
t1_2265
task1
11.1139
Cucurbit[7]uril
Cyclohexylmethanaminium
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Cyclohexylmethanaminium (SMILES: C1CCC(CC1)C[NH3+]) in aqueous solution at standard conditions. Provide a single n...
cb7_supplement
base
t1_7092
task1
3.6435
Cucurbit[7]uril
Strontium cation
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Strontium cation (SMILES: [Sr+2]) in aqueous solution at standard conditions. Provide a single numerical value. P...
cb7_supplement
base
t1_7287
task1
5.7482
Cucurbit[7]uril
Tryptophyl-Glycine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Tryptophyl-Glycine (SMILES: C1=CC=C2C(=C1)C(=CN2)CC(C(=O)NCC(=O)O)N) in aqueous solution at standard conditions. P...
cb7_supplement
base
t1_8891
task1
8.4857
Cucurbit[7]uril
5-Bromo-2-adamantanone
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 5-Bromo-2-adamantanone (SMILES: C1C2CC3CC(C2)(CC1C3=O)Br) in aqueous solution at standard conditions. Provide a si...
cb7_supplement
base
t1_9003
task1
4.2504
Cucurbit[7]uril
(2-(2-(2-(2-(4-(pyridine-2-yl)-1H-1,2,3-triazole-1-yl)ethoxy)ethoxy)ethoxy)ethan-1-ol)
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule (2-(2-(2-(2-(4-(pyridine-2-yl)-1H-1,2,3-triazole-1-yl)ethoxy)ethoxy)ethoxy)ethan-1-ol) (SMILES: OCCOCCOCCOCCN1C=C2...
cb7_supplement
base
t1_7085
task1
1.8513
Cucurbit[7]uril
Potassium cation
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Potassium cation (SMILES: [K+]) in aqueous solution at standard conditions. Provide a single numerical value. Put...
cb7_supplement
base