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234 values
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3
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1 value
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stringlengths
332
1.37k
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2 values
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stringclasses
1 value
t1_2567
task1
5.6628
Cucurbit[7]uril
N-((5-chlorofuran-2-yl)methyl)prop-2-en-1-amine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule N-((5-chlorofuran-2-yl)methyl)prop-2-en-1-amine (SMILES: C=CCNCC1=CC=C(Cl)O1) in aqueous solution at standard cond...
cb7_supplement
base
t1_4997
task1
1.0414
Cucurbit[7]uril
Acetonitrile
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Acetonitrile (SMILES: CC#N) in aqueous solution at standard conditions. Provide a single numerical value. Put you...
cb7_supplement
base
t1_8429
task1
14.301
Cucurbit[7]uril
bicyclo[2.2.2]octane-1,4-diyldimethanamine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule bicyclo[2.2.2]octane-1,4-diyldimethanamine (SMILES: NCC12CCC(CC1)(CC2)CN) in aqueous solution at standard conditio...
cb7_supplement
base
t1_9350
task1
4.9138
Cucurbit[7]uril
TMPyP4
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule TMPyP4 (SMILES: C[N+]1=CC=C(C=C1)C2=C3C=CC(=C(C4=NC(=C(C5=CC=C(N5)C(=C6C=CC2=N6)C7=CC=[N+](C=C7)C)C8=CC=[N+](C=C8)...
cb7_supplement
base
t1_8778
task1
5.9031
Cucurbit[7]uril
1-benzyl-3-methylimidazol-3-ium bromide
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1-benzyl-3-methylimidazol-3-ium bromide (SMILES: C[N+]1=CN(C=C1)CC2=CC=CC=C2.[Br-]) in aqueous solution at standar...
cb7_supplement
base
t1_5549
task1
4.1461
Cucurbit[7]uril
Tetramethylrhodamine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Tetramethylrhodamine (SMILES: CN(C)C1=CC2=C(C=C1)C(=C3C=CC(=[N+](C)C)C=C3O2)C4=CC=CC=C4C(=O)[O-]) in aqueous solut...
cb7_supplement
base
t1_5461
task1
5.9287
Cucurbit[7]uril
7-Methoxy-4-methylflavylium cation
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 7-Methoxy-4-methylflavylium cation (SMILES: COc1ccc2c(c1)[o+]c(cc2C)c1ccccc1) in aqueous solution at standard cond...
cb7_supplement
base
t1_8374
task1
6.2788
Cucurbit[7]uril
[C3mim]Br
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule [C3mim]Br (SMILES: CCCN1C[NH+](C=C1)C.[Br-]) in aqueous solution at standard conditions. Provide a single numerica...
cb7_supplement
base
t1_4061
task1
3.425
Cucurbit[7]uril
Rubidium chloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Rubidium chloride (SMILES: [Cl-].[Rb+]) in aqueous solution at standard conditions. Provide a single numerical val...
cb7_supplement
base
t1_8426
task1
12.3406
Cucurbit[7]uril
((Dimethylamino)methyl)ferrocene
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule ((Dimethylamino)methyl)ferrocene (SMILES: CN(C)CC1=CC=C[CH-]1.[CH-]1C=CC=C1.[Fe+2]) in aqueous solution at standar...
cb7_supplement
base
t1_5159
task1
4.5302
Cucurbit[7]uril
6-(p-toluidino)-2-naphthalenesulfonic acid sodium salt
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 6-(p-toluidino)-2-naphthalenesulfonic acid sodium salt (SMILES: CC1=CC=C(C=C1)NC2=CC3=C(C=C2)C=C(C=C3)S(=O)(=O)[O-...
cb7_supplement
base
t1_8777
task1
5.4771
Cucurbit[7]uril
2NpCH2ImidMe
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 2NpCH2ImidMe (SMILES: C[N+]1=CN(C=C1)CC2=CC3=CC=CC=C3C=C2.[Br-]) in aqueous solution at standard conditions. Provi...
cb7_supplement
base
t1_9248
task1
4.7987
Cucurbit[7]uril
cyanine dye LDP
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule cyanine dye LDP (SMILES: Nc1ccc(cc1)OCC[n+]1ccc(cc1)/C=C/c1ccc(cc1)N(C)C) in aqueous solution at standard conditio...
cb7_supplement
base
t1_4101
task1
5.0306
Cucurbit[7]uril
Barium chloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Barium chloride (SMILES: [Cl-].[Cl-].[Ba+2]) in aqueous solution at standard conditions. Provide a single numerica...
cb7_supplement
base
t1_6360
task1
6.3365
Cucurbit[7]uril
AM Phe
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule AM Phe (SMILES: C1=CC(=CC=C1CC(C(=O)O)N)CN) in aqueous solution at standard conditions. Provide a single numerical...
cb7_supplement
base
t1_4946
task1
7.1271
Cucurbit[7]uril
2,3-Diazabicyclo(2.2.2)oct-2-ene
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 2,3-Diazabicyclo(2.2.2)oct-2-ene (SMILES: C1CC2CCC1N=N2) in aqueous solution at standard conditions. Provide a sin...
cb7_supplement
base
t1_6268
task1
4.4822
Cucurbit[7]uril
Thr-Gly-Ser-Phe-Met-NH2
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Thr-Gly-Ser-Phe-Met-NH2 (SMILES: CSCC[C@@H](C(=O)N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)C([C@H](O)C)N)CO)Cc1cccc...
cb7_supplement
base
t1_7256
task1
2.69
Cucurbit[7]uril
11-aminoundecanoic acid
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 11-aminoundecanoic acid (SMILES: C(CCCCCN)CCCCC(=O)O) in aqueous solution at standard conditions. Provide a single...
cb7_supplement
base
t1_7285
task1
6.5563
Cucurbit[7]uril
Tyrosyl-Glycine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Tyrosyl-Glycine (SMILES: C1=CC(=CC=C1CC(C(=O)NCC(=O)O)N)O) in aqueous solution at standard conditions. Provide a s...
cb7_supplement
base
t1_5164
task1
7.7853
Cucurbit[7]uril
Flavopereirine perchlorate
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Flavopereirine perchlorate (SMILES: CCC1=C[N+]2=C(C=C1)C3=C(C=C2)C4=CC=CC=C4N3.[O-]Cl(=O)(=O)=O) in aqueous soluti...
cb7_supplement
base
t1_6366
task1
6.6776
Cucurbit[7]uril
tBu Phe-Gly-Gly
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule tBu Phe-Gly-Gly (SMILES: N[C@H](C(=O)NCC(=O)NCC(=O)O)Cc1ccc(cc1)C(C)(C)C) in aqueous solution at standard conditio...
cb7_supplement
base
t1_5768
task1
4.2041
Cucurbit[7]uril
L-Tyrosine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule L-Tyrosine (SMILES: C1=CC(=CC=C1CC(C(=O)O)N)O) in aqueous solution at standard conditions. Provide a single numeri...
cb7_supplement
base
t1_5405
task1
6.2996
Cucurbit[7]uril
6-Methoxy-1-methylquinolinium
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 6-Methoxy-1-methylquinolinium (SMILES: C[N+]1=CC=CC2=C1C=CC(=C2)OC) in aqueous solution at standard conditions. Pr...
cb7_supplement
base
t1_1915
task1
5.4024
Cucurbit[7]uril
4-(dimethylamino)benzonitrile
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 4-(dimethylamino)benzonitrile (SMILES: CN(C)C1=CC=C(C=C1)C#N) in aqueous solution at standard conditions. Provide ...
cb7_supplement
base
t1_4974
task1
4.4362
Cucurbit[7]uril
tert-Butylbenzylketone
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule tert-Butylbenzylketone (SMILES: O=C(C(C)(C)C)Cc1ccccc1) in aqueous solution at standard conditions. Provide a sing...
cb7_supplement
base
t1_5157
task1
4.7701
Cucurbit[7]uril
Progesterone
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Progesterone (SMILES: CC(=O)C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C) in aqueous solution at standard conditions. Provid...
cb7_supplement
base
t1_8529
task1
7.2279
Cucurbit[7]uril
Phenoxy-1,2-dioxetane
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Phenoxy-1,2-dioxetane (SMILES: COC1(OOC21[C@@H]1C[C@@H]3C[C@H]2C[C@H](C1)C3)c1cccc(c1)O) in aqueous solution at st...
cb7_supplement
base
t1_8390
task1
6.9494
Cucurbit[7]uril
1-methyl-3-octylimidazol-1-ium chloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1-methyl-3-octylimidazol-1-ium chloride (SMILES: CCCCCCCCN1C=C[N+](=C1)C.[Cl-]) in aqueous solution at standard co...
cb7_supplement
base
t1_8164
task1
12.6232
Cucurbit[7]uril
1-Adamantanamine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1-Adamantanamine (SMILES: C1C2CC3CC1CC(C2)(C3)N) in aqueous solution at standard conditions. Provide a single nume...
cb7_supplement
base
t1_3292
task1
7.1461
Cucurbit[7]uril
Cadaverine (fully protonated form)
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Cadaverine (fully protonated form) (SMILES: [NH3+]CCCCC[NH3+]) in aqueous solution at standard conditions. Provide...
cb7_supplement
base
t1_5051
task1
4.5051
Cucurbit[7]uril
Histamine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Histamine (SMILES: C1=C(NC=N1)CCN) in aqueous solution at standard conditions. Provide a single numerical value. ...
cb7_supplement
base
t1_2576
task1
6.7482
Cucurbit[7]uril
6-methyl-1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 6-methyl-1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole (SMILES: CC12C=CC3(O2)CNCC3C1) in aqueous solution at standard...
cb7_supplement
base
t1_6267
task1
3.7475
Cucurbit[7]uril
(2S)-2-((2S)-2-((2S)-2-(2-((3R)-2-amino-3-hydroxybutanamido)acetamido)propanamido)-3-phenylpropanamido)-4-methylpentanamide
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule (2S)-2-((2S)-2-((2S)-2-(2-((3R)-2-amino-3-hydroxybutanamido)acetamido)propanamido)-3-phenylpropanamido)-4-methylpe...
cb7_supplement
base
t1_6273
task1
6.5256
Cucurbit[7]uril
H-phe-leu-oh
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule H-phe-leu-oh (SMILES: CC(C)CC(C(=O)O)NC(=O)C(CC1=CC=CC=C1)N) in aqueous solution at standard conditions. Provide a...
cb7_supplement
base
t1_8389
task1
6.9191
Cucurbit[7]uril
1-methyl-3-octylimidazol-1-ium;bromide
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1-methyl-3-octylimidazol-1-ium;bromide (SMILES: CCCCCCCCN1C=C[N+](=C1)C.[Br-]) in aqueous solution at standard con...
cb7_supplement
base
t1_4969
task1
3.4914
Cucurbit[7]uril
2-butanone
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 2-butanone (SMILES: CCC(=O)C) in aqueous solution at standard conditions. Provide a single numerical value. Put y...
cb7_supplement
base
t1_8286
task1
11.0414
Cucurbit[7]uril
1-Adamantylammonium chloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1-Adamantylammonium chloride (SMILES: C1C2CC3CC1CC(C2)(C3)[NH3+].[Cl-]) in aqueous solution at standard conditions...
cb7_supplement
base
t1_6271
task1
7.3795
Cucurbit[7]uril
2-(2-amino-3-phenylpropanamido)-4-(methylthio)butanamide
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 2-(2-amino-3-phenylpropanamido)-4-(methylthio)butanamide (SMILES: CSCCC(C(=O)N)NC(=O)C(CC1=CC=CC=C1)N) in aqueous ...
cb7_supplement
base
t1_5771
task1
8.7924
Cucurbit[7]uril
Epiberberine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Epiberberine (SMILES: COC1=C(C=C2C(=C1)CC[N+]3=C2C=C4C=CC5=C(C4=C3)OCO5)OC) in aqueous solution at standard condit...
cb7_supplement
base
t1_7769
task1
0
Cucurbit[7]uril
1,1'-(3-(methoxycarbonyl)pentane-1,5-diyl)bis(pyridin-1-ium)
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1,1'-(3-(methoxycarbonyl)pentane-1,5-diyl)bis(pyridin-1-ium) (SMILES: COC(=O)C(CC[n+]1ccccc1)CC[n+]1ccccc1) in aqu...
cb7_supplement
base
t1_2024
task1
5.2742
Cucurbit[7]uril
1-methyl-3-[[4-[4-[(3-methylimidazol-3-ium-1-yl)methyl]phenyl]phenyl]methyl]imidazol-1-ium
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1-methyl-3-[[4-[4-[(3-methylimidazol-3-ium-1-yl)methyl]phenyl]phenyl]methyl]imidazol-1-ium (SMILES: C[N+]1=CN(C=C1...
cb7_supplement
base
t1_5548
task1
4.699
Cucurbit[7]uril
Rhodamine 6G
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Rhodamine 6G (SMILES: CCNC1=C(C=C2C(=C1)OC3=CC(=[NH+]CC)C(=CC3=C2C4=CC=CC=C4C(=O)OCC)C)C.[Cl-]) in aqueous solutio...
cb7_supplement
base
t1_8249
task1
6.5441
Cucurbit[7]uril
4,4'-Bipyridine dihydrochloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 4,4'-Bipyridine dihydrochloride (SMILES: n1ccc(cc1)c1ccncc1.Cl.Cl) in aqueous solution at standard conditions. Pro...
cb7_supplement
base
t1_6280
task1
5.3617
Cucurbit[7]uril
Trp-met-gly
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Trp-met-gly (SMILES: CSCCC(C(=O)NCC(=O)O)NC(=O)C(CC1=CNC2=CC=CC=C21)N) in aqueous solution at standard conditions....
cb7_supplement
base
t1_4104
task1
2.3404
Cucurbit[7]uril
Lithium chloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Lithium chloride (SMILES: [Li+].[Cl-]) in aqueous solution at standard conditions. Provide a single numerical valu...
cb7_supplement
base
t1_4056
task1
1.9443
Cucurbit[7]uril
Nitric acid
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Nitric acid (SMILES: [N+](=O)(O)[O-]) in aqueous solution at standard conditions. Provide a single numerical value...
cb7_supplement
base
t1_2555
task1
6.4771
Cucurbit[7]uril
N-(furan-2-ylmethyl)prop-2-en-1-amine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule N-(furan-2-ylmethyl)prop-2-en-1-amine (SMILES: C=CCNCC1=CC=CO1) in aqueous solution at standard conditions. Provid...
cb7_supplement
base
t1_7069
task1
6.7404
Cucurbit[7]uril
Hexyltrimethylammonium bromide
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Hexyltrimethylammonium bromide (SMILES: CCCCCC[N+](C)(C)C.[Br-]) in aqueous solution at standard conditions. Provi...
cb7_supplement
base
t1_5146
task1
4.79
Cucurbit[7]uril
1-Butanol
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1-Butanol (SMILES: CCCCO) in aqueous solution at standard conditions. Provide a single numerical value. Put your ...
cb7_supplement
base
t1_4941
task1
2.8926
Cucurbit[7]uril
N,N-dimethylformamide
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule N,N-dimethylformamide (SMILES: CN(C)C=O) in aqueous solution at standard conditions. Provide a single numerical va...
cb7_supplement
base
t1_8063
task1
9.5185
Cucurbit[7]uril
p-xylylenediamine dihydrochloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule p-xylylenediamine dihydrochloride (SMILES: NCc1ccc(cc1)CN.Cl.Cl) in aqueous solution at standard conditions. Provi...
cb7_supplement
base
t1_3044
task1
12.6075
Cucurbit[7]uril
(Trimethylamino)methyl)ferrocene
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule (Trimethylamino)methyl)ferrocene (SMILES: C[N+](C)(C)CC1=CC=C[CH-]1.[CH-]1C=CC=C1.[Fe+2]) in aqueous solution at s...
cb7_supplement
base
t1_4098
task1
4.5499
Cucurbit[7]uril
Strontium chloride hexahydrate
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Strontium chloride hexahydrate (SMILES: O.O.O.O.O.O.[Cl-].[Cl-].[Sr+2]) in aqueous solution at standard conditions...
cb7_supplement
base
t1_4939
task1
2.13
Cucurbit[7]uril
Dimethyl sulfoxide
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Dimethyl sulfoxide (SMILES: CS(=O)C) in aqueous solution at standard conditions. Provide a single numerical value....
cb7_supplement
base
t1_5553
task1
4.2304
Cucurbit[7]uril
Brilliant green
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Brilliant green (SMILES: CCN(CC)C1=CC=C(C=C1)C(=C2C=CC(=[N+](CC)CC)C=C2)C3=CC=CC=C3.OS(=O)(=O)[O-]) in aqueous sol...
cb7_supplement
base
t1_7284
task1
3.1139
Cucurbit[7]uril
Glycyl-phenylalanine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Glycyl-phenylalanine (SMILES: C1=CC=C(C=C1)CC(C(=O)O)NC(=O)CN) in aqueous solution at standard conditions. Provide...
cb7_supplement
base
t1_2298
task1
11.2304
Cucurbit[7]uril
N1,N1'-(hexane-1,6-diyl)bis(ethane-1,2-diaminium)
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule N1,N1'-(hexane-1,6-diyl)bis(ethane-1,2-diaminium) (SMILES: [NH3+]CC[NH2+]CCCCCC[NH2+]CC[NH3+]) in aqueous solution...
cb7_supplement
base
t1_6118
task1
3.4314
Cucurbit[7]uril
Gly-tyr-gly
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Gly-tyr-gly (SMILES: C1=CC(=CC=C1CC(C(=O)NCC(=O)O)NC(=O)CN)O) in aqueous solution at standard conditions. Provide ...
cb7_supplement
base
t1_4095
task1
4.1295
Cucurbit[7]uril
Calcium chloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Calcium chloride (SMILES: [Cl-].[Cl-].[Ca+2]) in aqueous solution at standard conditions. Provide a single numeric...
cb7_supplement
base
t1_4197
task1
3.24
Cucurbit[7]uril
Magnesium chloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Magnesium chloride (SMILES: [Mg+2].[Cl-].[Cl-]) in aqueous solution at standard conditions. Provide a single numer...
cb7_supplement
base
t1_7070
task1
6.8062
Cucurbit[7]uril
Octyltrimethylammonium bromide
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Octyltrimethylammonium bromide (SMILES: CCCCCCCC[N+](C)(C)C.[Br-]) in aqueous solution at standard conditions. Pro...
cb7_supplement
base
t1_1159
task1
5.0414
Cucurbit[7]uril
Rhodamine B benzyl ester
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Rhodamine B benzyl ester (SMILES: O=C(OCC1=CC=CC=C1)C2=CC=CC=C2C(C3=CC=C(N(CC)CC)C=C3O4)=C(C=C/5)C4=CC5=[N+](CC)\C...
cb7_supplement
base
t1_6269
task1
4.3495
Cucurbit[7]uril
Thr-Gly-Gly-Phe-Met-NH2
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Thr-Gly-Gly-Phe-Met-NH2 (SMILES: CSCC[C@@H](C(=O)N)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)C([C@H](O)C)N) in aqu...
cb7_supplement
base
t1_204
task1
5.3598
Cucurbit[7]uril
(E)-4-(4-(1,4-dioxa-7,13-dithia-10-azacyclopentadecan-10-yl)styryl)-1-methylpyridin-1-ium
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule (E)-4-(4-(1,4-dioxa-7,13-dithia-10-azacyclopentadecan-10-yl)styryl)-1-methylpyridin-1-ium (SMILES: C[N+](C=C1)=CC=...
cb7_supplement
base
t1_5842
task1
14.8899
Cucurbit[7]uril
(E)-4-(2-(7-(diethylamino)-2-oxo-2H-chromen-3-yl)vinyl)-1-(3-(trimethylammonio)propyl)pyridin-1-ium bromide
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule (E)-4-(2-(7-(diethylamino)-2-oxo-2H-chromen-3-yl)vinyl)-1-(3-(trimethylammonio)propyl)pyridin-1-ium bromide (SMILE...
cb7_supplement
base
t1_5932
task1
6.2788
Cucurbit[7]uril
Oxazine 1
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Oxazine 1 (SMILES: CCN(CC)C1=CC2=C(C=C1)N=C3C=CC(=[N+](CC)CC)C=C3O2) in aqueous solution at standard conditions. P...
cb7_supplement
base
t1_6639
task1
4.2405
Cucurbit[7]uril
D/L-Adrenaline
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule D/L-Adrenaline (SMILES: CNCC(C1=CC(=C(C=C1)O)O)O) in aqueous solution at standard conditions. Provide a single num...
cb7_supplement
base
t1_6836
task1
2.49
Cucurbit[7]uril
Ethanol
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Ethanol (SMILES: CCO) in aqueous solution at standard conditions. Provide a single numerical value. Put your fina...
cb7_supplement
base
t1_5407
task1
5.9031
Cucurbit[7]uril
Bis(3,5-dimethoxybenzyl)-4,4′-bipyridinium
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Bis(3,5-dimethoxybenzyl)-4,4′-bipyridinium (SMILES: COc1cc(cc(c1)OC)C[n+]1ccc(cc1)c1cc[n+](cc1)Cc1cc(OC)cc(c1)OC) ...
cb7_supplement
base
t1_5841
task1
10.0792
Cucurbit[7]uril
styrylcoumarin
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule styrylcoumarin (SMILES: CCN(c1ccc2c(c1)oc(=O)c(c2)/C=C/c1cc[n+](cc1)C)CC.[I-]) in aqueous solution at standard con...
cb7_supplement
base
t1_2874
task1
6.2788
Cucurbit[7]uril
Geranylamine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Geranylamine (SMILES: CC(=CCCC(=CCN)C)C) in aqueous solution at standard conditions. Provide a single numerical va...
cb7_supplement
base
t1_8781
task1
5.6128
Cucurbit[7]uril
N,N,N-trimethylanthracen-2-aminium chloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule N,N,N-trimethylanthracen-2-aminium chloride (SMILES: C[N+](c1ccc2c(c1)cc1c(c2)cccc1)(C)C.[Cl-]) in aqueous solutio...
cb7_supplement
base
t1_7094
task1
3.301
Cucurbit[7]uril
Europium(3+)
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Europium(3+) (SMILES: [Eu+3]) in aqueous solution at standard conditions. Provide a single numerical value. Put y...
cb7_supplement
base
t1_5552
task1
5.6021
Cucurbit[7]uril
Sulforhodamine b
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Sulforhodamine b (SMILES: CCN(CC)C1=CC2=C(C=C1)C(=C3C=CC(=[N+](CC)CC)C=C3O2)C4=C(C=C(C=C4)S(=O)(=O)O)S(=O)(=O)[O-]...
cb7_supplement
base
t1_7087
task1
2.8388
Cucurbit[7]uril
Cesium cation
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Cesium cation (SMILES: [Cs+]) in aqueous solution at standard conditions. Provide a single numerical value. Put y...
cb7_supplement
base
t1_8375
task1
6.7993
Cucurbit[7]uril
1H-​Imidazolium, 3-​butyl-​1-​methyl-​, bromide
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1H-​Imidazolium, 3-​butyl-​1-​methyl-​, bromide (SMILES: CCCC[N+]1=CN(C)C=C1.[Br-]) in aqueous solution at standar...
cb7_supplement
base
t1_7288
task1
2.4472
Cucurbit[7]uril
Glycyl-dl-Tryptophan
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Glycyl-dl-Tryptophan (SMILES: NCC(=O)NC(C(=O)O)Cc1c[nH]c2c1cccc2) in aqueous solution at standard conditions. Prov...
cb7_supplement
base
t1_6270
task1
3.4587
Cucurbit[7]uril
((3R)-2-amino-3-hydroxybutanoyl)glycyl-L-alanyl-L-phenylalanyl-L-leucine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule ((3R)-2-amino-3-hydroxybutanoyl)glycyl-L-alanyl-L-phenylalanyl-L-leucine (SMILES: CC(C[C@@H](C(=O)O)NC(=O)[C@@H](N...
cb7_supplement
base
t1_2258
task1
9.3222
Cucurbit[7]uril
6-Azaniumylhexylazanium
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 6-Azaniumylhexylazanium (SMILES: C(CCC[NH3+])CC[NH3+]) in aqueous solution at standard conditions. Provide a singl...
cb7_supplement
base
t1_6148
task1
7.0792
Cucurbit[7]uril
1,1'-bis(3-aminopropyl)-4,4'-bipyridinium
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1,1'-bis(3-aminopropyl)-4,4'-bipyridinium (SMILES: C1=C[N+](=CC=C1C2=CC=[N+](C=C2)CCCN)CCCN) in aqueous solution a...
cb7_supplement
base
t1_4998
task1
4.8129
Cucurbit[7]uril
Albendazole
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Albendazole (SMILES: CCCSC1=CC=C2C(NC(NC(OC)=O)=N2)=C1) in aqueous solution at standard conditions. Provide a sing...
cb7_supplement
base
t1_7
task1
3
Cucurbit[7]uril
Cholic acid
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Cholic acid (SMILES: CC(CCC(=O)O)C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C) in aqueous solution at standard conditi...
cb7_supplement
base
t1_8355
task1
5.2732
Cucurbit[7]uril
4-(diethylamino)benzonitrile
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 4-(diethylamino)benzonitrile (SMILES: CCN(CC)C1=CC=C(C=C1)C#N) in aqueous solution at standard conditions. Provide...
cb7_supplement
base
t1_2033
task1
8.8299
Cucurbit[7]uril
bis(dimethylpyridinium)diarylethene (open form)
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule bis(dimethylpyridinium)diarylethene (open form) (SMILES: C[N+]1=CC=C(C2=CC(C3=C(C4=C(C)SC(C(C=C5)=CC=[N+]5C)=C4)CC...
cb7_supplement
base
t1_8284
task1
6.2553
Cucurbit[7]uril
1,4-Phenylenediamine dihydrochloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1,4-Phenylenediamine dihydrochloride (SMILES: C1=CC(=CC=C1N)N.Cl.Cl) in aqueous solution at standard conditions. P...
cb7_supplement
base
t1_1844
task1
9.7853
Cucurbit[7]uril
Bicyclo[2.2.2]octane-1,4-diyldimethanol
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Bicyclo[2.2.2]octane-1,4-diyldimethanol (SMILES: C1CC2(CCC1(CC2)CO)CO) in aqueous solution at standard conditions....
cb7_supplement
base
t1_8890
task1
9.0253
Cucurbit[7]uril
5-Chloro-2-adamantanone
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 5-Chloro-2-adamantanone (SMILES: C1C2CC3CC(C2)(CC1C3=O)Cl) in aqueous solution at standard conditions. Provide a s...
cb7_supplement
base
t1_7283
task1
7.4771
Cucurbit[7]uril
Phenylalanylglycine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Phenylalanylglycine (SMILES: C1=CC=C(C=C1)CC(C(=O)NCC(=O)O)N) in aqueous solution at standard conditions. Provide ...
cb7_supplement
base
t1_2282
task1
5.5709
Cucurbit[7]uril
Cyclopentanone
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Cyclopentanone (SMILES: C1CCC(=O)C1) in aqueous solution at standard conditions. Provide a single numerical value....
cb7_supplement
base
t1_6145
task1
6.6335
Cucurbit[7]uril
1-(3-aminopropyl)-4-4'-bipyridinium
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1-(3-aminopropyl)-4-4'-bipyridinium (SMILES: [NH3+]CCC[n+]1ccc(cc1)c1ccncc1) in aqueous solution at standard condi...
cb7_supplement
base
t1_6359
task1
6.6021
Cucurbit[7]uril
tBu Phe
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule tBu Phe (SMILES: CC(C)(C)C1=CC=C(C=C1)CC(C(=O)O)N) in aqueous solution at standard conditions. Provide a single nu...
cb7_supplement
base
t1_6279
task1
5.8062
Cucurbit[7]uril
tyrosylmethionine
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule tyrosylmethionine (SMILES: CSCCC(C(=O)O)NC(=O)C(CC1=CC=C(C=C1)O)N) in aqueous solution at standard conditions. Pro...
cb7_supplement
base
t1_4119
task1
3.5
Cucurbit[7]uril
Nickel chloride
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Nickel chloride (SMILES: Cl[Ni]Cl) in aqueous solution at standard conditions. Provide a single numerical value. ...
cb7_supplement
base
t1_2417
task1
7.0253
Cucurbit[7]uril
(R)-1-(2-naphthyl)ethylammonium
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule (R)-1-(2-naphthyl)ethylammonium (SMILES: CC(C1=CC2=CC=CC=C2C=C1)[NH3+]) in aqueous solution at standard conditions...
cb7_supplement
base
t1_5409
task1
5.9031
Cucurbit[7]uril
1,1'-bis(3,5-diethoxybenzyl)-[4,4'-bipyridine]-1,1'-diium
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 1,1'-bis(3,5-diethoxybenzyl)-[4,4'-bipyridine]-1,1'-diium (SMILES: CCOc1cc(cc(c1)OCC)C[n+]1ccc(cc1)c1cc[n+](cc1)Cc...
cb7_supplement
base
t1_1790
task1
2.7782
Cucurbit[7]uril
6-Phenylamino-naphthalene-2-sulfonic acid anion
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 6-Phenylamino-naphthalene-2-sulfonic acid anion (SMILES: C1=CC=C(C=C1)NC2=CC3=C(C=C2)C=C(C=C3)S(=O)(=O)[O-]) in aq...
cb7_supplement
base
t1_6368
task1
6.2923
Cucurbit[7]uril
Gly-AM Phe-Gly
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Gly-AM Phe-Gly (SMILES: NCC(=O)N[C@H](C(=O)NCC(=O)O)Cc1ccc(cc1)CN) in aqueous solution at standard conditions. Pro...
cb7_supplement
base
t1_1
task1
3
Cucurbit[7]uril
Prednisolone
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Prednisolone (SMILES: CC12CC(C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C)O) in aqueous solution at standard conditions...
cb7_supplement
base
t1_8889
task1
10.5911
Cucurbit[7]uril
2-Adamantanone
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule 2-Adamantanone (SMILES: C1C2CC3CC1CC(C2)C3=O) in aqueous solution at standard conditions. Provide a single numeric...
cb7_supplement
base
t1_7093
task1
2.9294
Cucurbit[7]uril
Gadolinium(3+)
v2
You are an expert in supramolecular chemistry. Your task is to answer the following question. Question: Predict the binding affinity (logKa) between the host molecule Cucurbit[7]uril and the guest molecule Gadolinium(3+) (SMILES: [Gd+3]) in aqueous solution at standard conditions. Provide a single numerical value. Put...
cb7_supplement
base