row_idx
int64
f_0_ref__32
string
f_1_ref__31
string
f_2_ref__30
string
f_3_ref__29
string
f_4_ref__28
string
f_5_ref__27
string
f_6_ref__26
string
f_7_ref__25
string
f_8_ref__24
string
f_9_ref__23
string
f_10_ref__22
string
f_11_ref__21
string
f_12_ref__20
string
f_13_ref__19
string
f_14_ref__18
string
f_15_ref__17
string
f_16_ref__16
string
f_17_ref__15
string
f_18_ref__14
string
f_19_ref__13
string
f_20_ref__12
string
f_21_ref__11
string
f_22_ref__10
string
f_23_ref__9
string
f_24_ref__8
string
f_25_ref__7
string
f_26_ref__6
string
f_27_ref__5
string
f_28_ref__4
string
f_29_ref__3
string
f_30_ref__2
string
f_31_ref__1
string
f_32_ref_0
string
f_33_ref__1
string
f_34_ref__2
string
f_35_ref__3
string
f_36_ref__4
string
f_37_ref__5
string
f_38_ref__6
string
f_39_ref__7
string
f_40_ref__8
string
f_41_ref__9
string
f_42_ref__10
string
f_43_ref__11
string
f_44_ref__12
string
f_45_ref__13
string
f_46_ref__14
string
f_47_ref__15
string
f_48_ref__16
string
f_49_ref__17
string
f_50_ref__18
string
f_51_ref__19
string
f_52_ref__20
string
f_53_ref__21
string
f_54_ref__22
string
f_55_ref__23
string
f_56_ref__24
string
f_57_ref__25
string
f_58_ref__26
string
f_59_ref__27
string
f_60_ref__28
string
f_61_ref__29
string
f_62_ref__30
string
f_63_ref__31
string
f_64_ref__32
string
f_65_alt
string
f_66_k3_w513_AAA
float64
f_67_k3_w513_AAC
float64
f_68_k3_w513_AAG
float64
f_69_k3_w513_AAT
float64
f_70_k3_w513_ACA
float64
f_71_k3_w513_ACC
float64
f_72_k3_w513_ACG
float64
f_73_k3_w513_ACT
float64
f_74_k3_w513_AGA
float64
f_75_k3_w513_AGC
float64
f_76_k3_w513_AGG
float64
f_77_k3_w513_ATA
float64
f_78_k3_w513_ATC
float64
f_79_k3_w513_ATG
float64
f_80_k3_w513_CAA
float64
f_81_k3_w513_CAC
float64
f_82_k3_w513_CAG
float64
f_83_k3_w513_CCA
float64
f_84_k3_w513_CCC
float64
f_85_k3_w513_CCG
float64
f_86_k3_w513_CGA
float64
f_87_k3_w513_CGC
float64
f_88_k3_w513_CTA
float64
f_89_k3_w513_CTC
float64
f_90_k3_w513_GAA
float64
f_91_k3_w513_GAC
float64
f_92_k3_w513_GCA
float64
f_93_k3_w513_GCC
float64
f_94_k3_w513_GGA
float64
f_95_k3_w513_GTA
float64
f_96_k3_w513_TAA
float64
f_97_k3_w513_TCA
float64
target
int64
8,491
G
C
C
C
G
T
G
A
A
G
A
A
C
G
A
G
G
A
T
G
G
G
G
C
T
G
T
C
A
T
C
A
T
G
T
T
C
A
T
C
C
T
C
A
A
T
T
T
C
G
A
G
G
T
G
G
T
G
A
T
G
G
A
G
A
G
0.011742
0.015656
0.033268
0.009785
0.02544
0.046967
0.015656
0.015656
0.02544
0.035225
0.056751
0.007828
0.023483
0.041096
0.021526
0.048924
0.048924
0.072407
0.111546
0.02544
0.007828
0.005871
0.005871
0.043053
0.029354
0.02544
0.029354
0.050881
0.056751
0.013699
0.007828
0.031311
1
8,492
C
T
G
C
T
T
C
C
T
A
T
G
T
C
T
G
G
T
G
G
A
T
G
T
G
G
T
G
C
C
C
G
T
G
A
A
G
A
A
C
G
A
G
G
A
T
G
G
G
G
C
T
G
T
C
A
T
C
A
T
G
T
T
C
A
G
0.011742
0.015656
0.033268
0.009785
0.027397
0.043053
0.015656
0.013699
0.027397
0.041096
0.052838
0.007828
0.023483
0.041096
0.02544
0.04501
0.052838
0.072407
0.109589
0.02544
0.007828
0.005871
0.007828
0.041096
0.02544
0.027397
0.033268
0.054795
0.052838
0.011742
0.007828
0.029354
1
8,493
T
C
G
T
G
G
C
C
C
C
G
C
C
C
C
G
G
C
C
C
G
C
T
C
C
T
A
C
C
A
T
C
T
T
T
C
C
G
G
T
A
G
A
A
G
G
C
G
A
T
T
T
C
C
A
C
T
T
T
G
C
G
C
T
C
A
0.011742
0.017613
0.015656
0.001957
0.015656
0.033268
0.02544
0.019569
0.023483
0.031311
0.048924
0
0.017613
0.011742
0.011742
0.050881
0.050881
0.029354
0.101761
0.062622
0.027397
0.099804
0.015656
0.041096
0.021526
0.015656
0.058708
0.080235
0.027397
0.009785
0.001957
0.019569
1
8,494
G
C
G
C
C
G
C
G
C
T
G
C
C
G
C
G
C
A
G
A
T
C
G
C
G
C
A
G
G
C
A
C
T
G
C
T
G
G
G
C
G
C
C
G
A
G
G
A
G
C
G
C
A
A
A
G
T
G
G
A
A
A
T
C
G
G
0.005871
0.013699
0.015656
0.003914
0.015656
0.033268
0.02544
0.017613
0.021526
0.031311
0.04501
0
0.015656
0.011742
0.007828
0.050881
0.046967
0.033268
0.117417
0.068493
0.027397
0.101761
0.011742
0.041096
0.023483
0.019569
0.052838
0.080235
0.033268
0.009785
0.001957
0.015656
1
8,495
C
T
G
C
G
C
G
G
C
A
G
C
G
C
G
G
C
G
C
T
G
C
G
T
G
C
G
C
G
G
C
C
C
G
T
G
C
A
G
G
A
A
G
T
C
G
C
A
G
G
T
G
C
A
G
G
G
T
C
G
C
T
G
C
A
G
0.005871
0.011742
0.017613
0.003914
0.017613
0.029354
0.02544
0.021526
0.021526
0.037182
0.037182
0
0.015656
0.015656
0.007828
0.050881
0.04501
0.037182
0.119374
0.068493
0.027397
0.093933
0.011742
0.041096
0.023483
0.021526
0.048924
0.078278
0.037182
0.009785
0.001957
0.015656
1
8,496
G
G
T
G
A
T
G
C
A
G
C
G
A
C
C
C
T
G
C
A
C
C
T
G
C
G
A
C
T
T
C
C
T
G
C
A
C
G
G
G
C
C
G
C
G
C
A
C
G
C
A
G
C
G
C
C
G
C
G
C
T
G
C
C
G
C
0.005871
0.011742
0.017613
0.003914
0.017613
0.029354
0.02544
0.021526
0.021526
0.037182
0.037182
0
0.015656
0.015656
0.007828
0.050881
0.046967
0.039139
0.11546
0.068493
0.027397
0.093933
0.011742
0.041096
0.023483
0.023483
0.048924
0.074364
0.039139
0.009785
0.001957
0.015656
1
8,497
C
T
G
C
G
T
G
C
G
C
G
G
C
C
C
G
T
G
C
A
G
G
A
A
G
T
C
G
C
A
G
G
T
G
C
A
G
G
G
T
C
G
C
T
G
C
A
T
C
A
C
C
T
C
G
G
C
C
C
G
C
G
A
G
T
G
0.005871
0.011742
0.017613
0.003914
0.015656
0.031311
0.023483
0.023483
0.021526
0.039139
0.037182
0
0.015656
0.015656
0.007828
0.046967
0.050881
0.043053
0.119374
0.064579
0.027397
0.088063
0.011742
0.041096
0.023483
0.023483
0.050881
0.072407
0.041096
0.009785
0.001957
0.013699
1
8,498
T
G
C
G
C
C
G
T
C
A
T
C
T
A
C
T
G
C
A
A
C
G
A
C
G
G
C
T
T
C
T
G
C
G
A
G
C
T
G
T
G
C
G
G
C
T
A
C
T
C
G
C
G
G
G
C
C
G
A
G
G
T
G
A
T
G
0.005871
0.009785
0.017613
0.003914
0.019569
0.029354
0.02544
0.023483
0.017613
0.039139
0.041096
0.001957
0.017613
0.015656
0.007828
0.052838
0.054795
0.041096
0.107632
0.058708
0.029354
0.09002
0.011742
0.037182
0.021526
0.023483
0.056751
0.072407
0.039139
0.011742
0.001957
0.013699
1
8,499
C
G
G
C
C
C
G
C
G
A
G
T
A
G
C
C
G
C
A
C
A
G
C
T
C
G
C
A
G
A
A
G
C
C
G
T
C
G
T
T
G
C
A
G
T
A
G
A
T
G
A
C
G
G
C
G
C
A
G
T
T
C
T
C
C
A
0.005871
0.009785
0.017613
0.003914
0.017613
0.027397
0.02544
0.023483
0.017613
0.039139
0.041096
0.001957
0.017613
0.015656
0.007828
0.048924
0.054795
0.039139
0.105675
0.066536
0.029354
0.09002
0.011742
0.037182
0.021526
0.023483
0.056751
0.076321
0.039139
0.011742
0.001957
0.013699
1
8,500
A
G
C
C
G
C
A
C
A
G
C
T
C
G
C
A
G
A
A
G
C
C
G
T
C
G
T
T
G
C
A
G
T
A
G
A
T
G
A
C
G
G
C
G
C
A
G
T
T
C
T
C
C
A
C
C
C
G
A
G
C
G
T
T
G
C
0.005871
0.009785
0.017613
0.003914
0.015656
0.02544
0.023483
0.023483
0.017613
0.039139
0.041096
0.001957
0.017613
0.015656
0.007828
0.043053
0.054795
0.035225
0.097847
0.07045
0.029354
0.103718
0.011742
0.037182
0.021526
0.023483
0.056751
0.082192
0.039139
0.011742
0.001957
0.013699
1
8,501
C
C
A
A
C
G
C
T
C
G
G
G
T
G
G
A
G
A
A
C
T
G
C
G
C
C
G
T
C
A
T
C
T
A
C
T
G
C
A
A
C
G
A
C
G
G
C
T
T
C
T
G
C
G
A
G
C
T
G
T
G
C
G
G
C
G
0.005871
0.009785
0.017613
0.003914
0.015656
0.02544
0.023483
0.023483
0.017613
0.039139
0.041096
0.001957
0.017613
0.015656
0.007828
0.043053
0.054795
0.035225
0.097847
0.07045
0.029354
0.103718
0.011742
0.037182
0.021526
0.023483
0.056751
0.082192
0.039139
0.011742
0.001957
0.013699
1
8,502
C
G
C
C
A
A
C
G
C
T
C
G
G
G
T
G
G
A
G
A
A
C
T
G
C
G
C
C
G
T
C
A
T
C
T
A
C
T
G
C
A
A
C
G
A
C
G
G
C
T
T
C
T
G
C
G
A
G
C
T
G
T
G
C
G
C
0.005871
0.009785
0.017613
0.003914
0.015656
0.02544
0.023483
0.023483
0.017613
0.039139
0.041096
0.001957
0.017613
0.015656
0.007828
0.041096
0.054795
0.035225
0.099804
0.07045
0.029354
0.103718
0.011742
0.037182
0.021526
0.023483
0.054795
0.084149
0.039139
0.011742
0.001957
0.013699
1
8,503
C
C
C
C
G
C
C
C
C
C
C
T
A
G
G
C
C
G
T
A
A
G
T
T
C
A
T
C
A
T
C
G
C
C
A
A
C
G
C
T
C
G
G
G
T
G
G
A
G
A
A
C
T
G
C
G
C
C
G
T
C
A
T
C
T
T
0.005871
0.009785
0.015656
0.003914
0.015656
0.021526
0.021526
0.023483
0.015656
0.041096
0.041096
0.001957
0.017613
0.015656
0.007828
0.039139
0.056751
0.035225
0.097847
0.074364
0.027397
0.107632
0.011742
0.037182
0.021526
0.021526
0.054795
0.088063
0.041096
0.011742
0.001957
0.013699
1
8,504
A
C
T
C
T
C
C
T
C
C
C
C
G
C
C
C
C
C
C
T
A
G
G
C
C
G
T
A
A
G
T
T
C
A
T
C
A
T
C
G
C
C
A
A
C
G
C
T
C
G
G
G
T
G
G
A
G
A
A
C
T
G
C
G
C
A
0.005871
0.009785
0.017613
0.003914
0.015656
0.019569
0.023483
0.023483
0.015656
0.043053
0.041096
0.001957
0.017613
0.015656
0.005871
0.041096
0.056751
0.037182
0.093933
0.072407
0.027397
0.107632
0.011742
0.037182
0.023483
0.019569
0.054795
0.09002
0.041096
0.011742
0.001957
0.011742
1
8,505
G
T
T
C
T
C
C
A
C
C
C
G
A
G
C
G
T
T
G
G
C
G
A
T
G
A
T
G
A
A
C
T
T
A
C
G
G
C
C
T
A
G
G
G
G
G
G
C
G
G
G
G
A
G
G
A
G
A
G
T
G
C
G
C
G
C
0.005871
0.009785
0.017613
0.003914
0.015656
0.019569
0.023483
0.023483
0.015656
0.043053
0.039139
0.001957
0.017613
0.015656
0.005871
0.041096
0.054795
0.037182
0.09589
0.074364
0.027397
0.107632
0.011742
0.037182
0.023483
0.019569
0.054795
0.088063
0.043053
0.011742
0.001957
0.011742
1
8,506
G
T
G
T
A
C
T
T
A
C
C
C
A
G
C
C
T
G
G
G
C
C
C
C
T
T
T
G
G
A
G
G
C
C
C
G
A
G
G
A
G
T
C
G
C
C
T
C
C
T
G
G
T
G
G
G
G
C
A
G
T
G
G
T
G
T
0.011742
0.023483
0.029354
0.011742
0.029354
0.035225
0.005871
0.031311
0.02544
0.035225
0.07045
0.003914
0.019569
0.02544
0.021526
0.043053
0.068493
0.058708
0.078278
0.021526
0.009785
0.013699
0.011742
0.052838
0.023483
0.023483
0.035225
0.064579
0.048924
0.011742
0.019569
0.035225
1
8,507
G
T
T
G
G
A
C
G
C
A
G
T
G
T
T
G
G
A
G
G
T
G
C
C
G
G
T
G
C
C
T
G
T
G
C
G
T
T
T
C
C
T
C
T
T
C
C
T
G
C
T
G
C
T
G
G
G
C
C
C
G
A
G
T
A
C
0.007828
0.009785
0.029354
0.003914
0.02544
0.031311
0.011742
0.023483
0.027397
0.041096
0.074364
0.001957
0.015656
0.033268
0.029354
0.04501
0.060665
0.076321
0.076321
0.019569
0.009785
0.017613
0.017613
0.058708
0.011742
0.02544
0.048924
0.080235
0.056751
0.011742
0
0.017613
1
8,508
A
A
C
A
A
T
A
C
T
T
A
C
T
G
T
T
T
T
C
T
A
T
G
G
T
T
G
G
A
T
C
G
T
A
G
G
A
G
T
C
C
A
C
A
A
A
T
T
G
G
C
C
T
T
C
A
A
C
A
A
A
T
T
G
A
C
0.111546
0.021526
0.043053
0.09002
0.039139
0.017613
0.003914
0.027397
0.035225
0.017613
0.033268
0.037182
0.021526
0.043053
0.048924
0.021526
0.02544
0.027397
0.017613
0
0.003914
0
0.021526
0.023483
0.046967
0.017613
0.027397
0.017613
0.02544
0.027397
0.060665
0.04501
1
8,509
A
A
C
A
A
T
A
C
T
T
A
C
T
G
T
T
T
T
C
T
A
T
G
G
T
T
G
G
A
T
C
G
T
A
G
G
A
G
T
C
C
A
C
A
A
A
T
T
G
G
C
C
T
T
C
A
A
C
A
A
A
T
T
G
A
G
0.111546
0.021526
0.043053
0.09002
0.039139
0.017613
0.003914
0.027397
0.035225
0.017613
0.033268
0.037182
0.021526
0.043053
0.048924
0.021526
0.02544
0.027397
0.017613
0
0.003914
0
0.021526
0.023483
0.046967
0.017613
0.027397
0.017613
0.02544
0.027397
0.060665
0.04501
1
8,510
C
A
A
T
A
C
T
A
T
C
T
G
C
T
T
C
A
T
T
T
A
C
C
A
C
C
A
C
C
A
G
C
C
G
A
T
G
G
A
C
C
T
G
C
A
A
A
G
A
G
A
A
A
A
G
C
A
G
G
A
C
A
C
G
T
T
0.072407
0.029354
0.035225
0.037182
0.043053
0.043053
0.007828
0.02544
0.033268
0.027397
0.041096
0.023483
0.029354
0.041096
0.029354
0.046967
0.050881
0.054795
0.029354
0.005871
0.007828
0.001957
0.015656
0.02544
0.035225
0.023483
0.037182
0.019569
0.039139
0.019569
0.035225
0.033268
1
8,511
C
A
C
G
T
G
T
C
C
T
G
C
T
T
T
T
C
T
C
T
T
T
G
C
A
G
G
T
C
C
A
T
C
G
G
C
T
G
G
T
G
G
T
G
G
T
A
A
A
T
G
A
A
G
C
A
G
A
T
A
G
T
A
T
T
G
0.072407
0.027397
0.035225
0.037182
0.043053
0.043053
0.007828
0.02544
0.033268
0.027397
0.041096
0.023483
0.031311
0.041096
0.029354
0.046967
0.050881
0.054795
0.029354
0.005871
0.007828
0.001957
0.015656
0.02544
0.035225
0.023483
0.037182
0.019569
0.039139
0.019569
0.035225
0.033268
1
8,512
T
A
C
T
A
T
C
T
G
C
T
T
C
A
T
T
T
A
C
C
A
C
C
A
C
C
A
G
C
C
G
A
T
G
G
A
C
C
T
G
C
A
A
A
G
A
G
A
A
A
A
G
C
A
G
G
A
C
A
C
G
T
G
A
A
C
0.072407
0.027397
0.035225
0.037182
0.041096
0.043053
0.007828
0.02544
0.033268
0.027397
0.041096
0.023483
0.031311
0.041096
0.029354
0.04501
0.050881
0.054795
0.029354
0.005871
0.009785
0.003914
0.015656
0.02544
0.035225
0.023483
0.037182
0.019569
0.039139
0.019569
0.035225
0.033268
1
8,513
T
T
T
C
A
C
G
T
G
T
C
C
T
G
C
T
T
T
T
C
T
C
T
T
T
G
C
A
G
G
T
C
C
A
T
C
G
G
C
T
G
G
T
G
G
T
G
G
T
A
A
A
T
G
A
A
G
C
A
G
A
T
A
G
T
G
0.072407
0.027397
0.035225
0.037182
0.041096
0.043053
0.007828
0.023483
0.033268
0.027397
0.041096
0.023483
0.031311
0.041096
0.029354
0.04501
0.050881
0.054795
0.029354
0.005871
0.009785
0.003914
0.015656
0.02544
0.035225
0.023483
0.039139
0.019569
0.039139
0.019569
0.035225
0.033268
1
8,514
G
A
A
G
G
G
C
C
T
G
G
G
T
C
A
C
C
G
T
G
A
T
A
T
C
T
A
G
G
T
T
A
T
T
G
T
A
T
G
T
T
T
T
C
T
C
A
G
C
A
G
C
A
A
G
A
T
T
C
T
G
T
A
A
T
A
0.041096
0.02544
0.046967
0.050881
0.031311
0.02544
0.017613
0.031311
0.041096
0.037182
0.037182
0.035225
0.029354
0.033268
0.031311
0.027397
0.054795
0.031311
0.023483
0.007828
0.011742
0.001957
0.017613
0.027397
0.050881
0.027397
0.031311
0.023483
0.029354
0.02544
0.041096
0.052838
1
8,515
G
G
T
C
A
C
C
G
T
G
A
T
A
T
C
T
A
G
G
T
T
A
T
T
G
T
A
T
G
T
T
T
T
C
T
C
A
G
C
A
G
C
A
A
G
A
T
T
C
T
G
T
A
A
T
G
A
A
G
C
A
A
G
A
G
C
0.041096
0.027397
0.048924
0.048924
0.033268
0.02544
0.019569
0.031311
0.041096
0.039139
0.037182
0.035225
0.02544
0.031311
0.033268
0.027397
0.054795
0.029354
0.019569
0.007828
0.013699
0.001957
0.017613
0.027397
0.050881
0.027397
0.033268
0.023483
0.02544
0.027397
0.041096
0.052838
1
8,516
C
A
T
T
C
C
C
A
C
T
G
A
T
A
G
G
G
T
C
A
A
T
A
A
C
G
G
G
C
A
A
T
C
T
G
T
G
G
A
T
T
T
T
A
T
T
T
T
T
G
A
T
C
A
A
G
G
A
G
T
A
T
A
C
A
G
0.097847
0.039139
0.054795
0.064579
0.041096
0.009785
0.003914
0.052838
0.046967
0.021526
0.02544
0.039139
0.02544
0.019569
0.048924
0.021526
0.027397
0.017613
0.017613
0.001957
0.007828
0.001957
0.027397
0.037182
0.041096
0.009785
0.02544
0.009785
0.02544
0.037182
0.066536
0.033268
1
8,517
T
A
T
T
T
A
T
A
A
A
T
A
A
G
A
A
T
T
T
T
T
T
T
A
T
T
T
G
C
A
G
G
T
A
C
A
G
A
T
T
T
A
T
G
A
A
T
T
A
G
A
G
G
A
A
C
A
T
A
A
A
A
T
T
G
C
0.11546
0.031311
0.02544
0.062622
0.046967
0.019569
0
0.021526
0.043053
0.02544
0.029354
0.080235
0.027397
0.050881
0.035225
0.011742
0.033268
0.023483
0.011742
0.005871
0.003914
0.005871
0.031311
0.029354
0.035225
0.009785
0.027397
0.015656
0.023483
0.035225
0.048924
0.033268
1
8,518
T
T
T
G
T
T
T
T
T
T
A
C
T
C
T
C
C
C
A
C
A
G
T
G
G
C
G
C
T
G
C
T
C
G
G
A
C
A
C
C
G
T
T
G
G
C
T
A
C
C
A
A
A
G
C
A
A
A
G
A
A
G
G
C
C
T
0.091977
0.033268
0.048924
0.02544
0.029354
0.027397
0.003914
0.031311
0.035225
0.041096
0.046967
0.007828
0.015656
0.027397
0.043053
0.031311
0.046967
0.046967
0.02544
0.015656
0.013699
0.005871
0.015656
0.043053
0.041096
0.007828
0.043053
0.052838
0.029354
0.019569
0.023483
0.029354
1
8,519
C
A
C
C
G
T
T
G
G
C
T
A
C
C
A
A
A
G
C
A
A
A
G
A
A
G
G
C
C
T
T
T
T
T
A
A
C
C
T
G
A
A
G
A
A
A
A
A
G
A
G
G
A
G
A
A
A
C
A
A
A
A
C
A
T
A
0.107632
0.035225
0.04501
0.029354
0.035225
0.033268
0.003914
0.029354
0.035225
0.035225
0.043053
0.009785
0.011742
0.031311
0.043053
0.033268
0.043053
0.048924
0.023483
0.015656
0.007828
0.003914
0.017613
0.037182
0.043053
0.007828
0.039139
0.046967
0.027397
0.023483
0.023483
0.029354
1
8,520
T
G
G
A
T
G
A
G
G
C
A
C
T
G
C
G
G
G
T
G
A
G
T
C
C
T
G
T
G
A
C
C
C
C
T
T
C
T
C
C
T
G
T
C
G
A
C
C
T
G
C
A
A
T
C
T
T
C
T
T
C
T
G
C
T
A
0.058708
0.02544
0.033268
0.04501
0.027397
0.031311
0.007828
0.019569
0.037182
0.033268
0.058708
0.017613
0.037182
0.033268
0.029354
0.02544
0.054795
0.04501
0.039139
0.007828
0.005871
0.009785
0.02544
0.035225
0.031311
0.021526
0.035225
0.031311
0.048924
0.013699
0.041096
0.033268
1
8,521
C
C
T
G
T
T
C
T
C
A
G
T
G
T
G
G
T
C
A
G
T
G
T
T
A
C
C
A
T
C
C
A
T
A
C
T
G
T
G
T
C
A
G
T
A
T
T
A
A
G
G
T
A
A
A
C
A
T
C
C
T
T
A
A
A
C
0.09589
0.035225
0.048924
0.072407
0.052838
0.013699
0
0.043053
0.033268
0.023483
0.027397
0.086106
0.015656
0.037182
0.037182
0.021526
0.027397
0.017613
0.003914
0
0
0
0.02544
0.027397
0.035225
0.011742
0.019569
0.007828
0.023483
0.041096
0.082192
0.033268
1
8,522
T
G
C
C
T
G
T
T
C
T
C
A
G
T
G
T
G
G
T
C
A
G
T
G
T
T
A
C
C
A
T
C
C
A
T
A
C
T
G
T
G
T
C
A
G
T
A
T
T
A
A
G
G
T
A
A
A
C
A
T
C
C
T
T
A
T
0.09589
0.035225
0.048924
0.07045
0.052838
0.013699
0
0.043053
0.035225
0.023483
0.027397
0.086106
0.015656
0.035225
0.037182
0.021526
0.027397
0.017613
0.003914
0
0
0
0.02544
0.027397
0.035225
0.013699
0.019569
0.007828
0.023483
0.041096
0.082192
0.033268
1
8,523
C
A
A
C
A
G
C
T
C
C
G
A
T
T
C
C
A
C
T
T
T
T
C
A
G
C
T
T
T
G
A
C
C
T
G
C
C
T
C
G
G
C
C
A
C
C
T
C
G
C
C
C
C
G
A
C
A
G
T
C
C
T
G
C
A
T
0.11546
0.02544
0.048924
0.054795
0.039139
0.023483
0.005871
0.029354
0.046967
0.021526
0.035225
0.050881
0.027397
0.029354
0.031311
0.019569
0.031311
0.02544
0.013699
0.009785
0.011742
0.003914
0.015656
0.037182
0.029354
0.027397
0.013699
0.019569
0.029354
0.02544
0.068493
0.033268
1
8,524
C
A
A
C
A
A
T
T
T
C
A
T
T
G
T
T
T
C
A
C
T
G
T
T
A
A
T
T
A
T
A
G
C
G
A
A
G
G
A
A
G
A
T
G
C
A
A
A
C
T
G
T
G
C
A
G
T
G
T
G
C
G
A
C
A
T
0.076321
0.033268
0.035225
0.076321
0.048924
0.027397
0.005871
0.039139
0.031311
0.017613
0.02544
0.050881
0.02544
0.035225
0.046967
0.035225
0.035225
0.021526
0.011742
0.005871
0.005871
0.005871
0.031311
0.013699
0.037182
0.017613
0.041096
0.009785
0.015656
0.035225
0.060665
0.041096
1
8,525
G
G
C
G
A
C
C
T
T
G
G
T
G
C
T
G
G
T
G
G
C
C
C
A
C
T
T
C
A
C
C
A
T
G
G
T
G
A
T
G
T
A
G
T
A
C
T
C
C
C
T
G
G
A
A
A
C
G
C
C
A
A
A
C
A
G
0.013699
0.013699
0.023483
0.007828
0.021526
0.04501
0.027397
0.023483
0.033268
0.043053
0.031311
0.005871
0.009785
0.015656
0.013699
0.046967
0.066536
0.062622
0.084149
0.048924
0.021526
0.050881
0.003914
0.037182
0.021526
0.04501
0.035225
0.066536
0.033268
0.011742
0.009785
0.02544
1
8,526
T
A
G
C
C
C
T
A
A
C
C
G
C
T
C
C
A
G
G
T
G
C
T
G
C
C
G
A
C
G
C
T
C
C
G
G
G
T
G
C
G
G
G
G
G
C
C
A
C
C
G
C
G
G
G
C
A
T
C
C
A
C
T
G
G
G
0.015656
0.011742
0.019569
0.011742
0.011742
0.033268
0.017613
0.019569
0.013699
0.048924
0.041096
0.013699
0.005871
0.011742
0.013699
0.033268
0.052838
0.035225
0.080235
0.078278
0.019569
0.109589
0.013699
0.037182
0.015656
0.021526
0.050881
0.088063
0.033268
0.013699
0.013699
0.013699
1
8,527
C
C
T
A
A
G
C
G
A
G
G
A
G
G
C
C
G
C
G
G
G
C
G
C
C
T
A
C
G
C
G
C
C
G
C
T
C
A
C
G
G
C
C
C
A
G
G
G
C
A
C
C
A
T
T
C
T
C
A
T
C
A
A
C
C
T
0.001957
0.007828
0.009785
0.001957
0.015656
0.033268
0.031311
0.007828
0.005871
0.052838
0.039139
0
0.005871
0.007828
0.005871
0.050881
0.043053
0.031311
0.076321
0.103718
0.027397
0.142857
0.009785
0.043053
0.009785
0.019569
0.046967
0.113503
0.027397
0.009785
0.003914
0.013699
1
8,528
T
G
A
C
G
G
G
G
A
C
C
G
C
C
G
G
C
T
C
C
T
G
C
C
C
G
C
C
G
C
T
G
T
G
C
A
C
A
G
C
G
T
G
A
C
C
C
T
A
A
G
C
G
A
G
G
A
G
G
C
C
G
C
G
G
C
0.001957
0.007828
0.015656
0.001957
0.015656
0.029354
0.035225
0.007828
0.013699
0.050881
0.039139
0
0.007828
0.005871
0.007828
0.046967
0.039139
0.029354
0.068493
0.09589
0.031311
0.150685
0.011742
0.043053
0.013699
0.021526
0.039139
0.111546
0.02544
0.011742
0.003914
0.015656
1
8,529
G
C
G
G
C
G
G
A
C
G
A
C
C
A
G
G
G
C
C
G
G
C
T
G
C
T
C
T
A
C
A
G
C
G
A
C
T
T
C
C
T
C
A
C
T
T
T
C
C
T
G
G
A
C
C
G
C
G
A
C
G
A
C
G
G
A
0.007828
0.007828
0.027397
0.003914
0.011742
0.031311
0.033268
0.011742
0.027397
0.046967
0.050881
0
0.005871
0.001957
0.013699
0.04501
0.039139
0.037182
0.066536
0.078278
0.039139
0.099804
0.007828
0.062622
0.02544
0.027397
0.035225
0.091977
0.041096
0.007828
0
0.013699
1
8,530
G
C
T
G
G
T
G
A
A
G
G
A
C
C
T
G
A
G
C
C
C
C
G
G
G
G
A
C
C
G
C
G
T
G
C
T
G
G
C
G
G
C
G
G
A
C
G
A
C
C
A
G
G
G
C
C
G
G
C
T
G
C
T
C
T
A
0.007828
0.007828
0.029354
0.007828
0.009785
0.031311
0.02544
0.011742
0.027397
0.043053
0.054795
0
0.009785
0.001957
0.017613
0.039139
0.039139
0.033268
0.07045
0.076321
0.039139
0.103718
0.007828
0.060665
0.027397
0.027397
0.037182
0.09002
0.043053
0.003914
0
0.015656
1
8,531
C
C
G
G
C
C
C
T
G
G
T
C
G
T
C
C
G
C
C
G
C
C
A
G
C
A
C
G
C
G
G
T
C
C
C
C
G
G
G
G
C
T
C
A
G
G
T
C
C
T
T
C
A
C
C
A
G
C
T
T
G
G
T
G
C
T
0.007828
0.007828
0.029354
0.007828
0.009785
0.033268
0.023483
0.011742
0.027397
0.041096
0.054795
0
0.009785
0.001957
0.017613
0.037182
0.039139
0.033268
0.074364
0.078278
0.039139
0.099804
0.007828
0.060665
0.027397
0.029354
0.037182
0.088063
0.04501
0.003914
0
0.015656
1
8,532
G
C
T
C
C
A
G
G
T
G
C
A
C
C
G
T
G
G
C
C
G
A
G
C
C
C
G
G
G
A
A
G
C
A
G
C
C
T
C
C
C
G
A
T
T
T
G
G
C
C
G
C
C
A
C
C
G
A
G
T
T
C
T
C
T
T
0.007828
0.009785
0.029354
0.011742
0.017613
0.037182
0.023483
0.013699
0.031311
0.035225
0.056751
0
0.011742
0.003914
0.019569
0.04501
0.039139
0.035225
0.07045
0.066536
0.033268
0.088063
0.009785
0.058708
0.027397
0.033268
0.039139
0.068493
0.050881
0.003914
0.005871
0.015656
1
8,533
C
A
G
A
G
A
A
C
T
C
G
G
T
G
G
C
G
G
C
C
A
A
A
T
C
G
G
G
A
G
G
C
T
G
C
T
T
C
C
C
G
G
G
C
T
C
G
G
C
C
A
C
G
G
T
G
C
A
C
C
T
G
G
A
G
C
0.007828
0.009785
0.031311
0.011742
0.017613
0.037182
0.023483
0.013699
0.031311
0.035225
0.056751
0
0.011742
0.003914
0.019569
0.04501
0.039139
0.035225
0.068493
0.066536
0.033268
0.088063
0.009785
0.058708
0.027397
0.033268
0.039139
0.068493
0.050881
0.003914
0.005871
0.015656
1
8,534
G
G
G
T
C
G
G
A
T
C
C
G
G
G
G
G
G
C
C
A
G
G
G
C
C
A
G
C
T
T
A
C
C
T
G
C
T
T
T
C
A
C
C
G
A
G
C
A
G
T
G
G
A
T
A
T
G
T
G
C
C
T
T
G
G
G
0.019569
0.015656
0.035225
0.005871
0.013699
0.04501
0.015656
0.027397
0.02544
0.031311
0.054795
0.003914
0.021526
0.023483
0.021526
0.043053
0.054795
0.062622
0.058708
0.043053
0.031311
0.035225
0.005871
0.04501
0.031311
0.027397
0.035225
0.078278
0.037182
0.015656
0.003914
0.031311
1
8,535
T
G
A
A
C
G
C
T
T
T
G
G
C
C
A
T
C
T
C
G
G
T
G
A
T
G
A
A
C
C
A
G
T
G
G
C
C
A
G
G
A
G
T
G
A
A
A
C
T
G
C
G
G
G
T
G
A
C
C
G
A
G
G
G
C
G
0.007828
0.013699
0.031311
0.003914
0.019569
0.041096
0.023483
0.027397
0.027397
0.029354
0.048924
0.003914
0.015656
0.023483
0.021526
0.04501
0.050881
0.066536
0.074364
0.050881
0.027397
0.035225
0.005871
0.04501
0.021526
0.037182
0.035225
0.080235
0.043053
0.015656
0.005871
0.021526
1
8,536
T
G
A
A
C
G
C
T
T
T
G
G
C
C
A
T
C
T
C
G
G
T
G
A
T
G
A
A
C
C
A
G
T
G
G
C
C
A
G
G
A
G
T
G
A
A
A
C
T
G
C
G
G
G
T
G
A
C
C
G
A
G
G
G
C
C
0.007828
0.013699
0.031311
0.003914
0.019569
0.041096
0.023483
0.027397
0.027397
0.029354
0.048924
0.003914
0.015656
0.023483
0.021526
0.04501
0.050881
0.066536
0.074364
0.050881
0.027397
0.035225
0.005871
0.04501
0.021526
0.037182
0.035225
0.080235
0.043053
0.015656
0.005871
0.021526
1
8,537
A
A
G
T
T
G
A
A
C
G
C
T
T
T
G
G
C
C
A
T
C
T
C
G
G
T
G
A
T
G
A
A
C
C
A
G
T
G
G
C
C
A
G
G
A
G
T
G
A
A
A
C
T
G
C
G
G
G
T
G
A
C
C
G
A
A
0.007828
0.013699
0.031311
0.003914
0.019569
0.041096
0.023483
0.027397
0.027397
0.029354
0.048924
0.003914
0.015656
0.023483
0.021526
0.04501
0.050881
0.064579
0.074364
0.050881
0.027397
0.035225
0.005871
0.046967
0.021526
0.037182
0.035225
0.076321
0.046967
0.015656
0.005871
0.021526
1
8,538
T
T
T
C
A
C
T
C
C
T
G
G
C
C
A
C
T
G
G
T
T
C
A
T
C
A
C
C
G
A
G
A
T
G
G
C
C
A
A
A
G
C
G
T
T
C
A
A
C
T
T
G
T
C
C
T
T
A
C
A
C
C
T
C
T
A
0.007828
0.013699
0.027397
0.003914
0.019569
0.039139
0.027397
0.027397
0.029354
0.031311
0.048924
0.003914
0.013699
0.023483
0.019569
0.046967
0.052838
0.062622
0.072407
0.048924
0.02544
0.035225
0.005871
0.052838
0.019569
0.037182
0.037182
0.076321
0.04501
0.015656
0.005871
0.023483
1
8,539
A
C
A
C
A
T
T
C
C
A
C
G
C
C
C
C
G
G
C
G
C
T
G
G
G
T
T
C
C
T
A
C
C
T
G
A
G
T
C
A
T
C
A
G
C
C
T
G
T
C
C
G
C
T
C
C
G
G
T
G
T
T
T
T
C
G
0.027397
0.027397
0.043053
0.019569
0.023483
0.046967
0.011742
0.017613
0.035225
0.035225
0.052838
0.013699
0.021526
0.023483
0.013699
0.035225
0.043053
0.046967
0.080235
0.037182
0.017613
0.02544
0.013699
0.041096
0.048924
0.023483
0.017613
0.035225
0.054795
0.013699
0.02544
0.027397
1
8,540
T
C
A
T
C
A
G
C
C
T
G
T
C
C
G
C
T
C
C
G
G
T
G
T
T
T
T
C
T
T
C
A
T
C
C
T
T
A
A
A
T
A
T
G
A
T
G
T
C
G
G
G
G
T
T
G
T
A
A
T
T
G
G
G
G
A
0.027397
0.023483
0.043053
0.015656
0.023483
0.043053
0.007828
0.019569
0.039139
0.041096
0.052838
0.011742
0.021526
0.021526
0.013699
0.033268
0.046967
0.04501
0.078278
0.035225
0.023483
0.027397
0.017613
0.046967
0.046967
0.02544
0.023483
0.033268
0.056751
0.011742
0.021526
0.021526
1
8,541
A
G
G
G
G
T
C
A
G
C
T
T
T
T
T
G
G
G
G
T
G
C
C
T
C
C
T
C
T
T
C
C
C
G
A
A
C
C
C
C
C
T
G
C
C
C
G
G
T
C
C
G
C
A
C
G
C
C
A
G
T
C
C
C
G
T
0.02544
0.015656
0.035225
0.011742
0.02544
0.029354
0.011742
0.017613
0.037182
0.056751
0.043053
0.011742
0.019569
0.02544
0.011742
0.031311
0.043053
0.031311
0.064579
0.04501
0.033268
0.066536
0.015656
0.060665
0.037182
0.02544
0.035225
0.037182
0.052838
0.009785
0.013699
0.019569
1
8,542
T
G
T
G
C
C
C
G
C
A
G
G
T
G
A
A
G
A
T
T
T
G
G
T
T
C
C
A
G
A
A
C
C
G
G
C
G
G
A
T
G
A
A
A
T
G
G
A
A
A
C
G
C
A
G
C
A
A
A
A
A
G
G
C
C
T
0.021526
0.015656
0.02544
0.011742
0.011742
0.023483
0.02544
0.011742
0.021526
0.052838
0.052838
0.001957
0.003914
0.013699
0.019569
0.019569
0.048924
0.04501
0.09589
0.068493
0.017613
0.068493
0.011742
0.052838
0.031311
0.033268
0.029354
0.076321
0.066536
0.003914
0.001957
0.015656
1
8,543
C
A
G
C
T
C
C
A
G
C
A
G
C
T
G
C
T
G
G
C
T
G
G
T
G
A
A
G
G
C
G
G
T
G
C
G
C
G
G
C
C
G
G
C
G
G
C
A
C
T
T
C
C
C
C
A
G
G
A
G
G
T
T
C
G
A
0.007828
0.019569
0.029354
0.005871
0.017613
0.041096
0.011742
0.031311
0.013699
0.046967
0.050881
0.003914
0.009785
0.015656
0.027397
0.043053
0.056751
0.054795
0.074364
0.046967
0.021526
0.060665
0.011742
0.046967
0.019569
0.027397
0.041096
0.074364
0.039139
0.011742
0.007828
0.029354
1
8,544
C
A
G
G
T
G
G
A
A
G
T
C
A
T
T
T
T
G
A
C
A
G
T
C
C
A
T
T
T
G
A
A
T
T
T
G
G
C
T
T
C
A
C
A
T
T
C
C
G
T
A
A
C
C
C
A
G
A
T
G
A
T
G
T
C
A
0.080235
0.031311
0.037182
0.054795
0.048924
0.02544
0.005871
0.037182
0.021526
0.02544
0.029354
0.027397
0.015656
0.046967
0.046967
0.039139
0.039139
0.043053
0.031311
0.005871
0.003914
0.011742
0.013699
0.023483
0.041096
0.023483
0.023483
0.033268
0.019569
0.023483
0.033268
0.056751
1
8,545
G
A
A
G
T
C
A
T
T
T
T
G
A
C
A
G
T
C
C
A
T
T
T
G
A
A
T
T
T
G
G
C
T
T
C
A
C
A
T
T
C
C
G
T
A
A
C
C
C
A
G
A
T
G
A
T
G
T
C
T
T
C
A
G
G
A
0.076321
0.031311
0.037182
0.054795
0.048924
0.027397
0.005871
0.035225
0.023483
0.02544
0.029354
0.027397
0.015656
0.046967
0.048924
0.039139
0.039139
0.043053
0.031311
0.005871
0.003914
0.011742
0.011742
0.023483
0.041096
0.02544
0.023483
0.033268
0.019569
0.021526
0.033268
0.058708
1
8,546
G
A
A
G
T
C
A
T
T
T
T
G
A
C
A
G
T
C
C
A
T
T
T
G
A
A
T
T
T
G
G
C
T
T
C
A
C
A
T
T
C
C
G
T
A
A
C
C
C
A
G
A
T
G
A
T
G
T
C
T
T
C
A
G
G
C
0.076321
0.031311
0.037182
0.054795
0.048924
0.027397
0.005871
0.035225
0.023483
0.02544
0.029354
0.027397
0.015656
0.046967
0.048924
0.039139
0.039139
0.043053
0.031311
0.005871
0.003914
0.011742
0.011742
0.023483
0.041096
0.02544
0.023483
0.033268
0.019569
0.021526
0.033268
0.058708
1
8,547
A
G
T
C
A
T
T
T
T
G
A
C
A
G
T
C
C
A
T
T
T
G
A
A
T
T
T
G
G
C
T
T
C
A
C
A
T
T
C
C
G
T
A
A
C
C
C
A
G
A
T
G
A
T
G
T
C
T
T
C
A
G
G
G
A
G
0.076321
0.031311
0.037182
0.054795
0.048924
0.027397
0.005871
0.033268
0.023483
0.02544
0.029354
0.027397
0.015656
0.046967
0.048924
0.037182
0.041096
0.04501
0.031311
0.005871
0.003914
0.011742
0.011742
0.023483
0.041096
0.02544
0.023483
0.033268
0.019569
0.021526
0.033268
0.058708
1
8,548
A
T
T
T
T
G
A
C
A
G
T
C
C
A
T
T
T
G
A
A
T
T
T
G
G
C
T
T
C
A
C
A
T
T
C
C
G
T
A
A
C
C
C
A
G
A
T
G
A
T
G
T
C
T
T
C
A
G
G
G
A
A
T
T
T
C
0.076321
0.031311
0.037182
0.054795
0.046967
0.027397
0.005871
0.033268
0.023483
0.027397
0.031311
0.027397
0.015656
0.046967
0.048924
0.037182
0.043053
0.04501
0.031311
0.005871
0
0.011742
0.011742
0.023483
0.041096
0.023483
0.023483
0.035225
0.019569
0.021526
0.033268
0.058708
1
8,549
T
T
T
G
A
C
A
G
T
C
C
A
T
T
T
G
A
A
T
T
T
G
G
C
T
T
C
A
C
A
T
T
C
C
G
T
A
A
C
C
C
A
G
A
T
G
A
T
G
T
C
T
T
C
A
G
G
G
A
A
T
T
T
T
T
A
0.076321
0.031311
0.035225
0.054795
0.046967
0.027397
0.005871
0.033268
0.023483
0.027397
0.031311
0.027397
0.015656
0.046967
0.048924
0.037182
0.043053
0.04501
0.031311
0.005871
0
0.011742
0.011742
0.023483
0.039139
0.02544
0.023483
0.035225
0.019569
0.021526
0.033268
0.060665
1
8,550
T
T
T
G
A
C
A
G
T
C
C
A
T
T
T
G
A
A
T
T
T
G
G
C
T
T
C
A
C
A
T
T
C
C
G
T
A
A
C
C
C
A
G
A
T
G
A
T
G
T
C
T
T
C
A
G
G
G
A
A
T
T
T
T
T
G
0.076321
0.031311
0.035225
0.054795
0.046967
0.027397
0.005871
0.033268
0.023483
0.027397
0.031311
0.027397
0.015656
0.046967
0.048924
0.037182
0.043053
0.04501
0.031311
0.005871
0
0.011742
0.011742
0.023483
0.039139
0.02544
0.023483
0.035225
0.019569
0.021526
0.033268
0.060665
1
8,551
T
C
C
A
T
T
T
G
A
A
T
T
T
G
G
C
T
T
C
A
C
A
T
T
C
C
G
T
A
A
C
C
C
A
G
A
T
G
A
T
G
T
C
T
T
C
A
G
G
G
A
A
T
T
T
T
T
T
G
G
T
G
G
A
A
G
0.076321
0.033268
0.035225
0.054795
0.048924
0.029354
0.005871
0.031311
0.023483
0.027397
0.029354
0.027397
0.015656
0.050881
0.050881
0.035225
0.043053
0.046967
0.027397
0.005871
0
0.011742
0.011742
0.023483
0.039139
0.02544
0.023483
0.031311
0.019569
0.021526
0.033268
0.060665
1
8,552
T
C
C
A
T
T
T
G
A
A
T
T
T
G
G
C
T
T
C
A
C
A
T
T
C
C
G
T
A
A
C
C
C
A
G
A
T
G
A
T
G
T
C
T
T
C
A
G
G
G
A
A
T
T
T
T
T
T
G
G
T
G
G
A
A
T
0.076321
0.033268
0.035225
0.054795
0.048924
0.029354
0.005871
0.031311
0.023483
0.027397
0.029354
0.027397
0.015656
0.050881
0.050881
0.035225
0.043053
0.046967
0.027397
0.005871
0
0.011742
0.011742
0.023483
0.039139
0.02544
0.023483
0.031311
0.019569
0.021526
0.033268
0.060665
1
8,553
T
T
G
G
C
T
T
C
A
C
A
T
T
C
C
G
T
A
A
C
C
C
A
G
A
T
G
A
T
G
T
C
T
T
C
A
G
G
G
A
A
T
T
T
T
T
T
G
G
T
G
G
A
A
G
G
G
A
C
C
C
A
T
T
T
G
0.076321
0.033268
0.037182
0.054795
0.048924
0.029354
0.009785
0.029354
0.02544
0.027397
0.029354
0.027397
0.015656
0.048924
0.050881
0.035225
0.039139
0.048924
0.027397
0.005871
0
0.011742
0.011742
0.023483
0.041096
0.02544
0.017613
0.033268
0.021526
0.021526
0.033268
0.058708
1
8,554
A
G
A
T
A
A
A
A
T
T
T
T
G
C
T
T
T
C
T
A
A
C
C
A
A
A
A
G
C
C
A
G
T
G
T
C
T
T
C
C
A
A
C
A
T
G
G
A
C
A
A
A
T
A
C
A
C
C
T
T
T
C
C
T
T
G
0.091977
0.029354
0.066536
0.033268
0.043053
0.023483
0.001957
0.035225
0.064579
0.031311
0.031311
0.027397
0.031311
0.021526
0.031311
0.031311
0.048924
0.029354
0.013699
0.005871
0.005871
0.005871
0.027397
0.021526
0.048924
0.02544
0.029354
0.019569
0.02544
0.017613
0.048924
0.031311
1
8,555
G
T
C
T
G
A
C
A
T
T
T
T
C
A
G
C
T
G
T
G
G
T
G
T
G
A
T
T
T
C
C
A
C
G
C
T
G
A
G
A
A
G
C
C
G
G
G
A
G
G
A
G
G
G
C
G
C
T
G
T
G
G
A
C
A
T
0.050881
0.02544
0.037182
0.039139
0.046967
0.021526
0.011742
0.02544
0.04501
0.050881
0.035225
0.021526
0.015656
0.029354
0.037182
0.043053
0.060665
0.039139
0.031311
0.011742
0.001957
0.005871
0.015656
0.046967
0.039139
0.02544
0.04501
0.023483
0.041096
0.011742
0.02544
0.039139
1
8,556
C
A
T
G
C
A
T
G
C
A
A
C
A
T
C
G
T
T
T
A
C
T
G
A
C
A
G
T
G
T
T
T
T
G
T
C
C
A
G
A
A
C
C
T
A
A
G
A
T
A
A
A
A
A
T
A
A
T
T
T
T
A
T
T
G
C
0.097847
0.04501
0.052838
0.050881
0.041096
0.017613
0.015656
0.043053
0.060665
0.013699
0.029354
0.037182
0.027397
0.033268
0.033268
0.017613
0.027397
0.021526
0.005871
0.001957
0.005871
0
0.035225
0.031311
0.043053
0.013699
0.023483
0.009785
0.023483
0.041096
0.074364
0.02544
1
8,557
G
A
G
C
G
A
T
G
G
C
T
T
C
T
G
G
A
C
G
T
T
C
C
G
G
A
C
C
G
C
C
A
C
G
T
T
T
T
C
C
A
C
C
G
G
T
C
A
G
T
G
T
C
A
T
C
T
G
C
C
T
G
C
C
A
T
0.080235
0.019569
0.041096
0.056751
0.04501
0.017613
0.021526
0.019569
0.043053
0.037182
0.019569
0.017613
0.02544
0.041096
0.046967
0.039139
0.043053
0.035225
0.017613
0.019569
0.003914
0.009785
0.009785
0.02544
0.041096
0.037182
0.041096
0.02544
0.031311
0.009785
0.029354
0.048924
1
8,558
T
T
T
T
T
G
A
C
C
T
G
G
A
C
T
A
T
G
C
A
T
C
C
T
G
G
G
G
G
A
T
C
C
G
C
T
C
C
A
C
G
C
T
G
A
T
G
G
T
C
G
C
T
G
G
C
T
T
T
G
T
C
T
T
C
G
0.031311
0.013699
0.037182
0.019569
0.04501
0.027397
0.019569
0.023483
0.046967
0.035225
0.033268
0.011742
0.031311
0.031311
0.031311
0.048924
0.064579
0.060665
0.04501
0.017613
0.013699
0.027397
0.015656
0.021526
0.033268
0.043053
0.039139
0.046967
0.037182
0.009785
0.005871
0.031311
1
8,559
C
A
C
A
A
A
G
A
C
G
C
C
C
A
A
G
T
A
G
A
A
G
A
C
A
A
A
G
C
C
A
G
C
G
A
C
C
A
T
C
A
G
C
G
T
G
G
A
G
C
G
G
A
T
C
C
C
C
C
A
G
G
A
T
G
G
0.035225
0.015656
0.039139
0.021526
0.043053
0.02544
0.021526
0.019569
0.048924
0.037182
0.033268
0.011742
0.031311
0.029354
0.035225
0.04501
0.064579
0.058708
0.043053
0.019569
0.013699
0.027397
0.013699
0.021526
0.035225
0.041096
0.041096
0.046967
0.037182
0.007828
0.005871
0.029354
1
8,560
G
G
C
C
T
G
C
T
C
T
T
G
G
C
T
T
C
T
G
G
C
T
G
T
G
C
G
A
A
G
T
T
C
C
A
G
T
C
C
A
C
C
G
G
A
T
T
G
A
G
A
A
G
C
T
G
C
T
G
A
G
T
C
T
T
G
0.039139
0.023483
0.041096
0.041096
0.033268
0.021526
0.005871
0.031311
0.039139
0.058708
0.021526
0.015656
0.015656
0.037182
0.023483
0.031311
0.064579
0.050881
0.02544
0.031311
0.011742
0.017613
0.017613
0.027397
0.048924
0.019569
0.041096
0.050881
0.031311
0.017613
0.033268
0.031311
1
8,561
G
C
A
G
A
A
G
C
T
C
G
T
G
A
A
G
G
C
C
G
C
G
A
A
G
G
A
C
G
G
C
A
C
C
A
A
G
G
A
C
G
G
G
C
T
G
G
A
G
A
G
G
A
C
C
A
G
G
G
C
A
G
C
C
G
T
0.048924
0.027397
0.037182
0.007828
0.037182
0.033268
0.023483
0.015656
0.037182
0.033268
0.054795
0.003914
0.011742
0.023483
0.027397
0.037182
0.056751
0.037182
0.072407
0.033268
0.011742
0.029354
0.007828
0.037182
0.035225
0.039139
0.041096
0.048924
0.04501
0.005871
0.009785
0.029354
1
8,562
G
T
T
T
C
A
A
A
A
A
C
T
T
T
T
A
A
C
A
A
A
C
A
A
G
T
A
A
C
T
C
A
C
G
T
T
A
T
C
T
T
C
A
A
A
G
A
T
G
G
C
T
A
C
C
A
G
A
G
C
A
C
T
T
G
G
0.103718
0.054795
0.043053
0.033268
0.052838
0.023483
0.011742
0.039139
0.062622
0.023483
0.023483
0.019569
0.031311
0.02544
0.041096
0.031311
0.043053
0.021526
0.011742
0.003914
0.005871
0.005871
0.019569
0.043053
0.050881
0.005871
0.021526
0.007828
0.017613
0.035225
0.041096
0.04501
1
8,563
C
A
A
A
G
C
T
C
A
G
A
A
G
A
G
A
G
G
C
G
T
A
A
A
G
C
T
C
G
T
T
T
C
G
G
T
G
C
T
C
T
G
G
G
T
G
G
A
A
A
A
G
T
A
A
G
C
A
G
T
T
T
C
T
C
T
0.103718
0.046967
0.043053
0.035225
0.041096
0.027397
0.009785
0.033268
0.058708
0.031311
0.033268
0.02544
0.027397
0.027397
0.037182
0.021526
0.048924
0.023483
0.015656
0.001957
0.005871
0.005871
0.023483
0.041096
0.046967
0.009785
0.029354
0.011742
0.019569
0.033268
0.039139
0.041096
1
8,564
C
C
C
T
A
C
C
T
C
C
T
G
T
T
A
G
C
A
T
T
T
G
T
G
A
A
C
A
T
T
T
G
C
A
A
A
T
A
C
A
T
T
T
G
T
C
G
T
T
G
T
C
T
C
C
A
T
C
C
T
T
T
G
T
G
G
0.091977
0.021526
0.037182
0.064579
0.060665
0.011742
0.015656
0.029354
0.029354
0.031311
0.031311
0.031311
0.023483
0.041096
0.054795
0.033268
0.031311
0.027397
0.007828
0.005871
0.005871
0.003914
0.037182
0.017613
0.035225
0.031311
0.033268
0.017613
0.035225
0.031311
0.033268
0.037182
1
8,565
C
A
A
A
T
C
A
G
G
A
C
A
C
A
C
C
A
C
G
A
A
T
G
G
C
A
T
C
T
A
C
A
C
G
T
T
A
A
C
A
T
T
C
C
C
T
A
A
T
T
C
T
A
C
A
G
A
A
G
A
G
A
T
C
A
T
0.072407
0.02544
0.062622
0.035225
0.033268
0.017613
0.009785
0.043053
0.054795
0.04501
0.035225
0.017613
0.017613
0.023483
0.031311
0.033268
0.043053
0.029354
0.023483
0.003914
0.005871
0.003914
0.035225
0.037182
0.048924
0.013699
0.033268
0.031311
0.021526
0.031311
0.04501
0.035225
1
8,566
C
C
A
G
G
C
C
C
C
G
A
G
C
C
A
C
C
G
T
G
A
G
T
G
C
T
T
C
C
T
G
C
C
C
T
C
T
G
T
G
G
C
T
C
G
C
A
C
C
C
C
C
T
C
G
G
T
C
A
C
C
A
A
G
G
A
0.017613
0.011742
0.039139
0.011742
0.023483
0.037182
0.013699
0.009785
0.046967
0.052838
0.056751
0.005871
0.015656
0.02544
0.023483
0.046967
0.056751
0.062622
0.074364
0.019569
0.009785
0.035225
0.011742
0.058708
0.033268
0.021526
0.041096
0.052838
0.048924
0.003914
0.005871
0.02544
1
8,567
T
G
G
T
C
C
G
A
C
T
C
T
A
C
G
C
A
G
T
G
G
T
C
A
C
C
A
A
G
G
A
G
C
C
C
A
T
C
T
A
C
A
T
T
G
T
C
A
C
C
G
A
G
T
A
C
A
T
G
G
C
C
A
G
A
G
0.013699
0.019569
0.029354
0.009785
0.027397
0.048924
0.011742
0.013699
0.043053
0.037182
0.064579
0
0.019569
0.033268
0.015656
0.04501
0.052838
0.054795
0.076321
0.029354
0.011742
0.017613
0.011742
0.064579
0.029354
0.023483
0.033268
0.052838
0.048924
0.013699
0.013699
0.033268
1
8,568
G
C
C
T
G
T
T
C
C
C
T
C
A
G
A
T
T
G
C
T
G
A
A
G
G
G
A
T
G
G
C
A
T
A
C
A
T
T
G
A
G
C
G
C
A
T
G
A
A
T
T
C
C
A
T
C
C
A
C
C
G
C
G
A
C
C
0.023483
0.023483
0.035225
0.019569
0.048924
0.023483
0.011742
0.011742
0.029354
0.052838
0.062622
0.011742
0.019569
0.023483
0.031311
0.043053
0.060665
0.043053
0.068493
0.017613
0.013699
0.019569
0.017613
0.043053
0.035225
0.017613
0.037182
0.058708
0.041096
0.013699
0.011742
0.029354
1
8,569
C
G
C
A
G
G
G
A
C
C
A
T
G
T
A
T
C
A
G
A
G
C
T
T
G
G
C
C
A
T
G
G
C
C
G
C
C
A
A
C
C
A
C
G
G
G
C
C
G
C
C
C
C
C
C
G
G
T
G
C
C
T
A
C
G
A
0.043053
0.015656
0.017613
0.021526
0.013699
0.023483
0.031311
0.007828
0.023483
0.035225
0.046967
0.019569
0.015656
0.017613
0.02544
0.02544
0.031311
0.039139
0.072407
0.072407
0.021526
0.07045
0.009785
0.054795
0.015656
0.021526
0.033268
0.084149
0.050881
0.013699
0.011742
0.013699
1
8,570
A
C
C
G
C
G
G
G
T
G
C
C
C
T
C
C
T
C
C
G
T
G
C
T
G
G
G
C
C
T
G
T
C
C
T
A
C
C
T
C
C
A
G
G
G
C
G
G
A
G
G
C
G
C
G
G
G
C
T
C
T
G
C
G
T
T
0.003914
0.007828
0.015656
0.001957
0.015656
0.031311
0.029354
0.003914
0.019569
0.041096
0.04501
0.007828
0.005871
0.015656
0.009785
0.033268
0.037182
0.039139
0.082192
0.11546
0.019569
0.097847
0.007828
0.048924
0.011742
0.027397
0.035225
0.11546
0.052838
0.011742
0.003914
0.005871
1
8,571
C
C
G
C
T
C
C
G
C
C
G
C
C
A
C
T
G
C
T
G
T
A
G
G
C
C
G
C
A
G
C
T
T
C
C
C
G
G
G
C
C
G
C
G
G
C
A
G
C
G
G
C
G
G
C
G
G
C
G
G
C
C
G
C
C
A
0
0.001957
0.013699
0.001957
0.015656
0.031311
0.015656
0.007828
0.007828
0.050881
0.046967
0
0.003914
0.005871
0.003914
0.02544
0.048924
0.035225
0.09002
0.138943
0.021526
0.103718
0.009785
0.041096
0.009785
0.02544
0.031311
0.138943
0.048924
0.017613
0.003914
0.001957
1
8,572
C
A
G
G
C
C
C
G
C
A
C
C
C
G
C
C
G
C
T
C
C
G
C
C
G
C
C
A
C
T
G
C
T
G
T
A
G
G
C
C
G
C
A
G
C
T
T
C
C
C
G
G
G
C
C
G
C
G
G
C
A
G
C
G
G
A
0
0.001957
0.013699
0.001957
0.015656
0.029354
0.017613
0.007828
0.007828
0.050881
0.04501
0
0.003914
0.005871
0.003914
0.02544
0.048924
0.035225
0.091977
0.135029
0.021526
0.109589
0.009785
0.039139
0.009785
0.02544
0.029354
0.142857
0.04501
0.017613
0.003914
0.003914
1
8,573
A
T
C
T
C
G
C
C
T
C
C
A
G
A
G
C
G
G
G
G
T
G
G
A
C
A
T
A
G
C
C
C
C
A
C
A
G
T
T
G
A
C
A
C
A
C
T
C
T
C
T
G
C
C
T
T
C
T
G
A
G
A
A
G
T
T
0.023483
0.023483
0.033268
0.019569
0.035225
0.023483
0.017613
0.021526
0.066536
0.041096
0.039139
0.013699
0.02544
0.023483
0.031311
0.043053
0.050881
0.037182
0.052838
0.023483
0.013699
0.023483
0.013699
0.07045
0.033268
0.023483
0.037182
0.043053
0.033268
0.007828
0.015656
0.039139
1
8,574
G
T
G
T
C
A
A
C
T
G
T
G
G
G
G
C
T
A
T
G
T
C
C
A
C
C
C
C
G
C
T
C
T
G
G
A
G
G
C
G
A
G
A
T
G
G
G
A
C
G
G
G
T
C
A
C
T
A
T
C
T
G
T
G
C
A
0.02544
0.02544
0.035225
0.023483
0.037182
0.023483
0.015656
0.023483
0.066536
0.039139
0.037182
0.013699
0.02544
0.023483
0.033268
0.043053
0.048924
0.037182
0.048924
0.023483
0.011742
0.023483
0.017613
0.066536
0.031311
0.023483
0.035225
0.043053
0.031311
0.007828
0.019569
0.039139
1
8,575
T
T
G
C
A
C
A
G
A
T
A
G
T
G
A
C
C
C
G
T
C
C
C
A
T
C
T
C
G
C
C
T
C
C
A
G
A
G
C
G
G
G
G
T
G
G
A
C
A
T
A
G
C
C
C
C
A
C
A
G
T
T
G
A
C
G
0.02544
0.02544
0.035225
0.023483
0.037182
0.023483
0.015656
0.023483
0.066536
0.043053
0.037182
0.013699
0.02544
0.023483
0.033268
0.043053
0.046967
0.037182
0.048924
0.023483
0.011742
0.023483
0.017613
0.066536
0.031311
0.023483
0.035225
0.043053
0.031311
0.007828
0.019569
0.037182
1
8,576
A
G
G
C
A
T
T
G
C
A
C
A
C
A
G
G
C
T
C
G
C
C
C
T
C
C
G
C
A
T
T
G
C
G
G
C
G
C
C
A
C
A
G
C
G
T
G
G
T
G
G
T
G
G
T
G
G
T
C
T
G
G
C
A
G
T
0.035225
0.015656
0.043053
0.021526
0.035225
0.023483
0.019569
0.02544
0.037182
0.023483
0.062622
0.005871
0.013699
0.035225
0.027397
0.043053
0.046967
0.039139
0.037182
0.02544
0.009785
0.035225
0.015656
0.043053
0.031311
0.02544
0.054795
0.058708
0.04501
0.019569
0.021526
0.023483
1
8,577
C
C
C
A
C
G
T
A
C
C
C
C
G
T
G
G
A
G
C
T
T
C
A
T
G
T
A
G
A
G
G
C
C
G
C
A
G
G
C
A
T
T
G
C
A
C
A
C
A
G
G
C
T
C
G
C
C
C
T
C
C
G
C
A
T
T
0.037182
0.015656
0.043053
0.019569
0.041096
0.021526
0.019569
0.023483
0.035225
0.029354
0.058708
0.009785
0.015656
0.041096
0.029354
0.041096
0.04501
0.037182
0.037182
0.02544
0.007828
0.029354
0.019569
0.039139
0.029354
0.023483
0.054795
0.058708
0.041096
0.02544
0.021526
0.023483
1
8,578
C
C
C
A
C
G
T
A
C
C
C
C
G
T
G
G
A
G
C
T
T
C
A
T
G
T
A
G
A
G
G
C
C
G
C
A
G
G
C
A
T
T
G
C
A
C
A
C
A
G
G
C
T
C
G
C
C
C
T
C
C
G
C
A
T
G
0.037182
0.015656
0.043053
0.019569
0.041096
0.021526
0.019569
0.023483
0.035225
0.029354
0.058708
0.009785
0.015656
0.041096
0.029354
0.041096
0.04501
0.037182
0.037182
0.02544
0.007828
0.029354
0.019569
0.039139
0.029354
0.023483
0.054795
0.058708
0.041096
0.02544
0.021526
0.023483
1
8,579
C
C
C
A
C
G
T
A
C
C
C
C
G
T
G
G
A
G
C
T
T
C
A
T
G
T
A
G
A
G
G
C
C
G
C
A
G
G
C
A
T
T
G
C
A
C
A
C
A
G
G
C
T
C
G
C
C
C
T
C
C
G
C
A
T
A
0.037182
0.015656
0.043053
0.019569
0.041096
0.021526
0.019569
0.023483
0.035225
0.029354
0.058708
0.009785
0.015656
0.041096
0.029354
0.041096
0.04501
0.037182
0.037182
0.02544
0.007828
0.029354
0.019569
0.039139
0.029354
0.023483
0.054795
0.058708
0.041096
0.02544
0.021526
0.023483
1
8,580
C
C
G
T
T
T
T
C
T
G
G
T
T
T
G
G
A
T
C
C
C
C
T
C
T
T
T
C
C
G
C
A
T
T
G
C
A
A
G
A
G
G
C
C
T
G
G
G
G
A
C
C
T
G
G
A
G
G
G
T
C
A
C
A
A
C
0.054795
0.019569
0.037182
0.031311
0.035225
0.02544
0.009785
0.019569
0.04501
0.033268
0.052838
0.02544
0.033268
0.027397
0.02544
0.037182
0.058708
0.041096
0.043053
0.017613
0.009785
0.009785
0.019569
0.035225
0.039139
0.017613
0.037182
0.048924
0.037182
0.015656
0.023483
0.033268
1
8,581
G
T
T
G
C
C
T
G
T
G
C
T
G
T
C
C
A
G
G
T
C
G
C
T
G
G
G
T
G
T
G
G
T
T
C
G
G
T
C
G
T
T
G
T
C
C
A
C
A
T
C
C
A
G
G
T
G
T
A
T
C
T
G
T
T
C
0.019569
0.029354
0.031311
0.017613
0.035225
0.035225
0.017613
0.021526
0.048924
0.02544
0.052838
0.003914
0.033268
0.027397
0.019569
0.029354
0.058708
0.050881
0.056751
0.035225
0.021526
0.007828
0.013699
0.04501
0.048924
0.041096
0.023483
0.029354
0.074364
0.009785
0.011742
0.023483
1
8,582
T
A
A
A
A
A
C
A
T
T
C
A
T
G
T
T
A
G
T
A
T
A
A
A
G
A
T
A
T
T
A
C
C
T
A
T
A
A
G
G
A
T
A
G
C
C
G
T
G
G
T
A
C
T
T
G
G
A
A
C
G
A
A
A
T
G
0.091977
0.050881
0.033268
0.060665
0.060665
0.029354
0.003914
0.037182
0.031311
0.011742
0.02544
0.076321
0.013699
0.050881
0.035225
0.023483
0.033268
0.029354
0.009785
0.001957
0.001957
0
0.031311
0.007828
0.046967
0.009785
0.023483
0.011742
0.015656
0.046967
0.064579
0.029354
1
8,583
A
A
G
T
G
A
A
A
G
T
A
C
T
G
A
A
T
A
A
C
A
T
C
A
C
T
A
A
T
G
A
T
C
T
C
A
G
A
C
T
G
A
A
A
G
A
T
T
G
G
G
A
A
C
A
T
T
C
T
C
A
G
A
C
C
G
0.09589
0.031311
0.041096
0.072407
0.037182
0.017613
0.003914
0.033268
0.043053
0.015656
0.02544
0.084149
0.033268
0.04501
0.029354
0.015656
0.039139
0.019569
0.009785
0.001957
0.003914
0.001957
0.011742
0.02544
0.058708
0.009785
0.015656
0.005871
0.023483
0.035225
0.056751
0.056751
1
8,584
A
A
T
T
G
G
C
T
G
T
G
C
A
T
T
G
C
T
A
T
C
G
C
C
T
G
C
T
G
A
A
G
T
T
T
C
T
C
T
T
C
C
T
T
G
G
C
T
C
T
T
C
T
A
C
A
G
T
G
G
C
A
A
A
T
A
0.076321
0.031311
0.043053
0.076321
0.04501
0.009785
0.001957
0.037182
0.037182
0.037182
0.017613
0.076321
0.027397
0.050881
0.04501
0.019569
0.027397
0.019569
0.001957
0.001957
0.001957
0.001957
0.043053
0.013699
0.041096
0.011742
0.035225
0.015656
0.013699
0.031311
0.064579
0.043053
1
8,585
C
T
C
T
C
T
C
C
T
T
A
C
G
T
T
T
T
G
C
A
G
T
T
A
C
T
G
G
C
C
A
A
C
A
C
C
T
T
C
C
C
A
A
G
A
A
C
A
A
G
C
G
T
C
C
A
A
A
A
G
A
A
C
C
A
T
0.072407
0.027397
0.037182
0.043053
0.023483
0.035225
0.009785
0.031311
0.04501
0.035225
0.041096
0.017613
0.017613
0.019569
0.048924
0.02544
0.048924
0.04501
0.031311
0.009785
0.005871
0.021526
0.021526
0.04501
0.037182
0.017613
0.037182
0.031311
0.029354
0.029354
0.021526
0.037182
1
8,586
A
A
G
G
A
A
G
A
A
G
G
G
A
T
G
T
T
T
C
C
A
A
C
G
G
T
C
A
T
A
A
T
T
T
G
T
T
T
G
T
A
C
C
A
C
A
T
A
C
C
A
T
C
T
A
C
C
C
T
G
C
T
T
A
G
C
0.082192
0.035225
0.058708
0.031311
0.035225
0.029354
0.011742
0.029354
0.056751
0.017613
0.039139
0.039139
0.037182
0.033268
0.048924
0.017613
0.029354
0.037182
0.019569
0.003914
0.009785
0.005871
0.029354
0.02544
0.039139
0.017613
0.029354
0.02544
0.02544
0.035225
0.037182
0.027397
1
8,587
A
C
T
T
T
A
C
C
T
T
G
T
G
C
T
A
T
T
T
T
C
C
A
G
A
A
C
T
G
T
T
C
T
A
G
T
G
A
G
G
A
A
C
C
C
T
A
T
C
C
A
C
A
T
G
A
C
A
T
C
T
T
T
C
T
C
0.074364
0.037182
0.043053
0.052838
0.041096
0.031311
0.003914
0.039139
0.04501
0.023483
0.037182
0.046967
0.013699
0.031311
0.021526
0.029354
0.043053
0.029354
0.009785
0.013699
0.005871
0
0.029354
0.029354
0.060665
0.029354
0.017613
0.005871
0.04501
0.019569
0.052838
0.037182
1
8,588
A
T
T
C
C
C
A
T
T
T
C
A
C
T
T
G
A
G
A
A
T
G
C
T
C
T
A
C
T
T
A
C
C
C
A
G
A
T
A
A
C
C
A
C
C
A
T
T
T
A
T
A
C
T
G
A
A
A
C
G
T
T
C
A
T
G
0.07045
0.037182
0.054795
0.027397
0.029354
0.039139
0.005871
0.041096
0.048924
0.023483
0.037182
0.035225
0.019569
0.031311
0.02544
0.023483
0.046967
0.041096
0.02544
0.013699
0.005871
0.005871
0.021526
0.027397
0.058708
0.029354
0.011742
0.017613
0.035225
0.027397
0.037182
0.04501
1
8,589
T
T
T
G
T
C
T
T
T
T
T
C
T
C
A
G
G
G
A
C
T
G
T
T
C
A
G
T
C
T
T
A
C
A
C
T
G
A
A
T
G
A
A
C
G
T
T
T
C
A
G
T
A
T
A
A
A
T
G
G
T
G
G
T
T
A
0.074364
0.041096
0.054795
0.021526
0.031311
0.037182
0.007828
0.04501
0.041096
0.02544
0.039139
0.033268
0.015656
0.029354
0.029354
0.023483
0.050881
0.039139
0.02544
0.013699
0.005871
0.007828
0.017613
0.027397
0.050881
0.031311
0.015656
0.021526
0.033268
0.02544
0.037182
0.046967
1
8,590
T
A
A
A
T
A
A
T
G
A
T
A
C
C
T
G
G
G
T
C
A
T
A
A
C
T
G
A
G
C
A
A
C
T
A
A
A
A
C
C
T
T
T
A
A
C
A
G
T
G
A
A
T
T
T
G
G
A
T
T
T
C
C
A
A
G
0.060665
0.04501
0.04501
0.046967
0.056751
0.031311
0.003914
0.031311
0.031311
0.023483
0.041096
0.054795
0.031311
0.046967
0.039139
0.02544
0.037182
0.023483
0.017613
0.003914
0.003914
0
0.021526
0.023483
0.043053
0.021526
0.007828
0.015656
0.021526
0.031311
0.052838
0.060665
1