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EU lawmakers bag late night deal on ‘global first’ AI rules
Penalties and entry into force
Penalties for non-compliance can lead to fines ranging from €35 million or 7% of global turnover to €7.5 million or 1.5 % of turnover, depending on the infringement and size of the company, per the parliament.
The Council’s PR further stipulates that the higher sanction (7%) would apply for violations of the banned AI applications, while penalties of 1.5% would be levied for the supply of incorrect information. Additionally, it says sanctions of 3% could be imposed for violations of other AI Act obligations but also notes that the provisional agreement allows for “more proportionate caps” on administrative fines for SMEs and start-ups in case of infringements. So there looks to be some scope for AI startups to face smaller penalties for infringements than AI giants may invite.
The deal agreed today also allows for a phased entry into force after the law is adopted — with six months allowed until rules on prohibited use cases kick in; 12 months for transparency and governance requirements; and 24 months for all other requirements.
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37401
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EU lawmakers bag late night deal on ‘global first’ AI rules
The Council’s PR further stipulates that the higher sanction (7%) would apply for violations of the banned AI applications, while penalties of 1.5% would be levied for the supply of incorrect information. Additionally, it says sanctions of 3% could be imposed for violations of other AI Act obligations but also notes that the provisional agreement allows for “more proportionate caps” on administrative fines for SMEs and start-ups in case of infringements. So there looks to be some scope for AI startups to face smaller penalties for infringements than AI giants may invite.
The deal agreed today also allows for a phased entry into force after the law is adopted — with six months allowed until rules on prohibited use cases kick in; 12 months for transparency and governance requirements; and 24 months for all other requirements. So the full force of the EU’s AI Act may not be felt until 2026.
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37402
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EU lawmakers bag late night deal on ‘global first’ AI rules
The Council’s PR further stipulates that the higher sanction (7%) would apply for violations of the banned AI applications, while penalties of 1.5% would be levied for the supply of incorrect information. Additionally, it says sanctions of 3% could be imposed for violations of other AI Act obligations but also notes that the provisional agreement allows for “more proportionate caps” on administrative fines for SMEs and start-ups in case of infringements. So there looks to be some scope for AI startups to face smaller penalties for infringements than AI giants may invite.
The deal agreed today also allows for a phased entry into force after the law is adopted — with six months allowed until rules on prohibited use cases kick in; 12 months for transparency and governance requirements; and 24 months for all other requirements. So the full force of the EU’s AI Act may not be felt until 2026.
Carme Artigas, Spain’s secretary of state for digital and AI issues, who led the Council’s negotiations on the file as the country has held the rotating Council presidency since the summer, hailed the agreement on the heavily contested file as “the biggest milestone in the history of digital information in Europe”; both for the bloc’s single digital market — but also, she suggested, “for the world”.
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37403
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EU lawmakers bag late night deal on ‘global first’ AI rules
So there looks to be some scope for AI startups to face smaller penalties for infringements than AI giants may invite.
The deal agreed today also allows for a phased entry into force after the law is adopted — with six months allowed until rules on prohibited use cases kick in; 12 months for transparency and governance requirements; and 24 months for all other requirements. So the full force of the EU’s AI Act may not be felt until 2026.
Carme Artigas, Spain’s secretary of state for digital and AI issues, who led the Council’s negotiations on the file as the country has held the rotating Council presidency since the summer, hailed the agreement on the heavily contested file as “the biggest milestone in the history of digital information in Europe”; both for the bloc’s single digital market — but also, she suggested, “for the world”.
“We have achieved the first international regulation for artificial intelligence in the world,” she announced during a post-midnight press conference to confirm the political agreement, adding: “We feel very proud.”
The law will support European developers, startups and future scale-ups by giving them “legal certainty with technical certainty”, she predicted.
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37404
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EU lawmakers bag late night deal on ‘global first’ AI rules
So the full force of the EU’s AI Act may not be felt until 2026.
Carme Artigas, Spain’s secretary of state for digital and AI issues, who led the Council’s negotiations on the file as the country has held the rotating Council presidency since the summer, hailed the agreement on the heavily contested file as “the biggest milestone in the history of digital information in Europe”; both for the bloc’s single digital market — but also, she suggested, “for the world”.
“We have achieved the first international regulation for artificial intelligence in the world,” she announced during a post-midnight press conference to confirm the political agreement, adding: “We feel very proud.”
The law will support European developers, startups and future scale-ups by giving them “legal certainty with technical certainty”, she predicted.
Speaking on behalf of the European Parliament, co-rapporteurs Dragoș Tudorache and Brando Benifei said their objective had been to deliver AI legislation that would ensure the ecosystem developed with a “human centric approach” which respects fundamental rights and European values.
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37405
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EU lawmakers bag late night deal on ‘global first’ AI rules
Carme Artigas, Spain’s secretary of state for digital and AI issues, who led the Council’s negotiations on the file as the country has held the rotating Council presidency since the summer, hailed the agreement on the heavily contested file as “the biggest milestone in the history of digital information in Europe”; both for the bloc’s single digital market — but also, she suggested, “for the world”.
“We have achieved the first international regulation for artificial intelligence in the world,” she announced during a post-midnight press conference to confirm the political agreement, adding: “We feel very proud.”
The law will support European developers, startups and future scale-ups by giving them “legal certainty with technical certainty”, she predicted.
Speaking on behalf of the European Parliament, co-rapporteurs Dragoș Tudorache and Brando Benifei said their objective had been to deliver AI legislation that would ensure the ecosystem developed with a “human centric approach” which respects fundamental rights and European values.
Their assessment of the outcome was equally upbeat — citing the inclusion in the agreed text of a total ban on the use of AI for predictive policing and for biometric categorization as major wins.
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37406
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EU lawmakers bag late night deal on ‘global first’ AI rules
“We have achieved the first international regulation for artificial intelligence in the world,” she announced during a post-midnight press conference to confirm the political agreement, adding: “We feel very proud.”
The law will support European developers, startups and future scale-ups by giving them “legal certainty with technical certainty”, she predicted.
Speaking on behalf of the European Parliament, co-rapporteurs Dragoș Tudorache and Brando Benifei said their objective had been to deliver AI legislation that would ensure the ecosystem developed with a “human centric approach” which respects fundamental rights and European values.
Their assessment of the outcome was equally upbeat — citing the inclusion in the agreed text of a total ban on the use of AI for predictive policing and for biometric categorization as major wins.
“Finally we got in the right track, defending fundamental rights to the necessity that is there for our democracies to endure such incredible changes,” said Benifei, who just a few weeks ago was sounding doubtful a deal could be found.
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37407
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EU lawmakers bag late night deal on ‘global first’ AI rules
Speaking on behalf of the European Parliament, co-rapporteurs Dragoș Tudorache and Brando Benifei said their objective had been to deliver AI legislation that would ensure the ecosystem developed with a “human centric approach” which respects fundamental rights and European values.
Their assessment of the outcome was equally upbeat — citing the inclusion in the agreed text of a total ban on the use of AI for predictive policing and for biometric categorization as major wins.
“Finally we got in the right track, defending fundamental rights to the necessity that is there for our democracies to endure such incredible changes,” said Benifei, who just a few weeks ago was sounding doubtful a deal could be found. “We are the first ones in the world to have a horizontal legislation that has this direction on fundamental rights, that supports the development of AI in our continent, and that is up to date to the frontier of the artificial intelligence with the most powerful models under clear obligation.
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37408
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EU lawmakers bag late night deal on ‘global first’ AI rules
Speaking on behalf of the European Parliament, co-rapporteurs Dragoș Tudorache and Brando Benifei said their objective had been to deliver AI legislation that would ensure the ecosystem developed with a “human centric approach” which respects fundamental rights and European values.
Their assessment of the outcome was equally upbeat — citing the inclusion in the agreed text of a total ban on the use of AI for predictive policing and for biometric categorization as major wins.
“Finally we got in the right track, defending fundamental rights to the necessity that is there for our democracies to endure such incredible changes,” said Benifei, who just a few weeks ago was sounding doubtful a deal could be found. “We are the first ones in the world to have a horizontal legislation that has this direction on fundamental rights, that supports the development of AI in our continent, and that is up to date to the frontier of the artificial intelligence with the most powerful models under clear obligation. So I think we delivered.”
“We have always been questioned whether there is enough protection, whether there is enough stimulant for innovation in this text, and I can say, this balance is there,” added Tudorache.
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37409
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EU lawmakers bag late night deal on ‘global first’ AI rules
Their assessment of the outcome was equally upbeat — citing the inclusion in the agreed text of a total ban on the use of AI for predictive policing and for biometric categorization as major wins.
“Finally we got in the right track, defending fundamental rights to the necessity that is there for our democracies to endure such incredible changes,” said Benifei, who just a few weeks ago was sounding doubtful a deal could be found. “We are the first ones in the world to have a horizontal legislation that has this direction on fundamental rights, that supports the development of AI in our continent, and that is up to date to the frontier of the artificial intelligence with the most powerful models under clear obligation. So I think we delivered.”
“We have always been questioned whether there is enough protection, whether there is enough stimulant for innovation in this text, and I can say, this balance is there,” added Tudorache. “We have safeguards, we have all the provisions that we need, the redress that we need in giving trust to our citizens in the interaction with AI, in the products in the services that they will interact with from now on.
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37410
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EU lawmakers bag late night deal on ‘global first’ AI rules
“Finally we got in the right track, defending fundamental rights to the necessity that is there for our democracies to endure such incredible changes,” said Benifei, who just a few weeks ago was sounding doubtful a deal could be found. “We are the first ones in the world to have a horizontal legislation that has this direction on fundamental rights, that supports the development of AI in our continent, and that is up to date to the frontier of the artificial intelligence with the most powerful models under clear obligation. So I think we delivered.”
“We have always been questioned whether there is enough protection, whether there is enough stimulant for innovation in this text, and I can say, this balance is there,” added Tudorache. “We have safeguards, we have all the provisions that we need, the redress that we need in giving trust to our citizens in the interaction with AI, in the products in the services that they will interact with from now on.
“We now have to use this blueprint to seek now global convergence because this is a global challenge for everyone.
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37411
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EU lawmakers bag late night deal on ‘global first’ AI rules
“We are the first ones in the world to have a horizontal legislation that has this direction on fundamental rights, that supports the development of AI in our continent, and that is up to date to the frontier of the artificial intelligence with the most powerful models under clear obligation. So I think we delivered.”
“We have always been questioned whether there is enough protection, whether there is enough stimulant for innovation in this text, and I can say, this balance is there,” added Tudorache. “We have safeguards, we have all the provisions that we need, the redress that we need in giving trust to our citizens in the interaction with AI, in the products in the services that they will interact with from now on.
“We now have to use this blueprint to seek now global convergence because this is a global challenge for everyone. And I think that with the work that we’ve done, as difficult as it was — and it was difficult, this was a marathon negotiation by all standards, looking at all precedents so far — but I think we delivered.”
The EU’s internal market commissioner, Thierry Breton, also chipped in with his two euro-cents — describing the agreement clinched a little before midnight Brussels’ time as “historic”.
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37412
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EU lawmakers bag late night deal on ‘global first’ AI rules
So I think we delivered.”
“We have always been questioned whether there is enough protection, whether there is enough stimulant for innovation in this text, and I can say, this balance is there,” added Tudorache. “We have safeguards, we have all the provisions that we need, the redress that we need in giving trust to our citizens in the interaction with AI, in the products in the services that they will interact with from now on.
“We now have to use this blueprint to seek now global convergence because this is a global challenge for everyone. And I think that with the work that we’ve done, as difficult as it was — and it was difficult, this was a marathon negotiation by all standards, looking at all precedents so far — but I think we delivered.”
The EU’s internal market commissioner, Thierry Breton, also chipped in with his two euro-cents — describing the agreement clinched a little before midnight Brussels’ time as “historic”. “It is a full package. It is a complete deal.
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37413
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EU lawmakers bag late night deal on ‘global first’ AI rules
“We have safeguards, we have all the provisions that we need, the redress that we need in giving trust to our citizens in the interaction with AI, in the products in the services that they will interact with from now on.
“We now have to use this blueprint to seek now global convergence because this is a global challenge for everyone. And I think that with the work that we’ve done, as difficult as it was — and it was difficult, this was a marathon negotiation by all standards, looking at all precedents so far — but I think we delivered.”
The EU’s internal market commissioner, Thierry Breton, also chipped in with his two euro-cents — describing the agreement clinched a little before midnight Brussels’ time as “historic”. “It is a full package. It is a complete deal. And this is why we spent so much time,” he intoned. “This is balancing user safety, innovation for startups, while also respecting… our fundamental rights and our European values.”
Clear road ahead?
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37414
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EU lawmakers bag late night deal on ‘global first’ AI rules
“We now have to use this blueprint to seek now global convergence because this is a global challenge for everyone. And I think that with the work that we’ve done, as difficult as it was — and it was difficult, this was a marathon negotiation by all standards, looking at all precedents so far — but I think we delivered.”
The EU’s internal market commissioner, Thierry Breton, also chipped in with his two euro-cents — describing the agreement clinched a little before midnight Brussels’ time as “historic”. “It is a full package. It is a complete deal. And this is why we spent so much time,” he intoned. “This is balancing user safety, innovation for startups, while also respecting… our fundamental rights and our European values.”
Clear road ahead?
Despite the EU very visibly patting itself on the back tonight on securing a deal on ‘world-first’ AI rules, it’s not quite yet the end of the road for the bloc’s lawmaking process as there are still some formal steps to go — not least the final text will face votes in the parliament and the Council to adopt it.
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37415
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EU lawmakers bag late night deal on ‘global first’ AI rules
“It is a full package. It is a complete deal. And this is why we spent so much time,” he intoned. “This is balancing user safety, innovation for startups, while also respecting… our fundamental rights and our European values.”
Clear road ahead?
Despite the EU very visibly patting itself on the back tonight on securing a deal on ‘world-first’ AI rules, it’s not quite yet the end of the road for the bloc’s lawmaking process as there are still some formal steps to go — not least the final text will face votes in the parliament and the Council to adopt it. But given how much division and disagreement there has been over how (or even whether) to regulate AI the biggest obstacles have been dismantled with this political deal and the path to passing the EU AI Act in the coming months looks clear.
The Commission is certainly projecting confidence.
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37416
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EU lawmakers bag late night deal on ‘global first’ AI rules
“It is a full package. It is a complete deal. And this is why we spent so much time,” he intoned. “This is balancing user safety, innovation for startups, while also respecting… our fundamental rights and our European values.”
Clear road ahead?
Despite the EU very visibly patting itself on the back tonight on securing a deal on ‘world-first’ AI rules, it’s not quite yet the end of the road for the bloc’s lawmaking process as there are still some formal steps to go — not least the final text will face votes in the parliament and the Council to adopt it. But given how much division and disagreement there has been over how (or even whether) to regulate AI the biggest obstacles have been dismantled with this political deal and the path to passing the EU AI Act in the coming months looks clear.
The Commission is certainly projecting confidence. Per Breton, work to implement the agreement starts immediately with the set up of an AI Office within the EU’s executive — which will have the job of coordinating with the Member State oversight bodies that will need to enforce the rules on AI firms; and overseeing the most advanced AI models, including by contributing to fostering standards and testing practices.
|
37417
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EU lawmakers bag late night deal on ‘global first’ AI rules
Despite the EU very visibly patting itself on the back tonight on securing a deal on ‘world-first’ AI rules, it’s not quite yet the end of the road for the bloc’s lawmaking process as there are still some formal steps to go — not least the final text will face votes in the parliament and the Council to adopt it. But given how much division and disagreement there has been over how (or even whether) to regulate AI the biggest obstacles have been dismantled with this political deal and the path to passing the EU AI Act in the coming months looks clear.
The Commission is certainly projecting confidence. Per Breton, work to implement the agreement starts immediately with the set up of an AI Office within the EU’s executive — which will have the job of coordinating with the Member State oversight bodies that will need to enforce the rules on AI firms; and overseeing the most advanced AI models, including by contributing to fostering standards and testing practices. A scientific panel of independent experts will be appointed to advise the AI Office about GPAI models.
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37418
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EU lawmakers bag late night deal on ‘global first’ AI rules
But given how much division and disagreement there has been over how (or even whether) to regulate AI the biggest obstacles have been dismantled with this political deal and the path to passing the EU AI Act in the coming months looks clear.
The Commission is certainly projecting confidence. Per Breton, work to implement the agreement starts immediately with the set up of an AI Office within the EU’s executive — which will have the job of coordinating with the Member State oversight bodies that will need to enforce the rules on AI firms; and overseeing the most advanced AI models, including by contributing to fostering standards and testing practices. A scientific panel of independent experts will be appointed to advise the AI Office about GPAI models. “We will welcome new colleagues… a lot of them,” said Breton.
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37419
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EU lawmakers bag late night deal on ‘global first’ AI rules
But given how much division and disagreement there has been over how (or even whether) to regulate AI the biggest obstacles have been dismantled with this political deal and the path to passing the EU AI Act in the coming months looks clear.
The Commission is certainly projecting confidence. Per Breton, work to implement the agreement starts immediately with the set up of an AI Office within the EU’s executive — which will have the job of coordinating with the Member State oversight bodies that will need to enforce the rules on AI firms; and overseeing the most advanced AI models, including by contributing to fostering standards and testing practices. A scientific panel of independent experts will be appointed to advise the AI Office about GPAI models. “We will welcome new colleagues… a lot of them,” said Breton. “We will work — starting tomorrow — to get ready.”
Opposition to the inclusion in the AI package of tiered rules for general purpose AIs has been led, in recent weeks, by France — and French AI startup Mistral, which had been lobbying for a total carve out from obligations for foundational models/GPAIs.
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37420
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EU lawmakers bag late night deal on ‘global first’ AI rules
The Commission is certainly projecting confidence. Per Breton, work to implement the agreement starts immediately with the set up of an AI Office within the EU’s executive — which will have the job of coordinating with the Member State oversight bodies that will need to enforce the rules on AI firms; and overseeing the most advanced AI models, including by contributing to fostering standards and testing practices. A scientific panel of independent experts will be appointed to advise the AI Office about GPAI models. “We will welcome new colleagues… a lot of them,” said Breton. “We will work — starting tomorrow — to get ready.”
Opposition to the inclusion in the AI package of tiered rules for general purpose AIs has been led, in recent weeks, by France — and French AI startup Mistral, which had been lobbying for a total carve out from obligations for foundational models/GPAIs. In the event the deal agreed by the Spanish presidency does contain some obligations for GPAIs and foundation models.
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37421
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EU lawmakers bag late night deal on ‘global first’ AI rules
The Commission is certainly projecting confidence. Per Breton, work to implement the agreement starts immediately with the set up of an AI Office within the EU’s executive — which will have the job of coordinating with the Member State oversight bodies that will need to enforce the rules on AI firms; and overseeing the most advanced AI models, including by contributing to fostering standards and testing practices. A scientific panel of independent experts will be appointed to advise the AI Office about GPAI models. “We will welcome new colleagues… a lot of them,” said Breton. “We will work — starting tomorrow — to get ready.”
Opposition to the inclusion in the AI package of tiered rules for general purpose AIs has been led, in recent weeks, by France — and French AI startup Mistral, which had been lobbying for a total carve out from obligations for foundational models/GPAIs. In the event the deal agreed by the Spanish presidency does contain some obligations for GPAIs and foundation models. So it’s not the total carve out Mistral and its lobbyists have been pushing for.
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37422
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EU lawmakers bag late night deal on ‘global first’ AI rules
A scientific panel of independent experts will be appointed to advise the AI Office about GPAI models. “We will welcome new colleagues… a lot of them,” said Breton. “We will work — starting tomorrow — to get ready.”
Opposition to the inclusion in the AI package of tiered rules for general purpose AIs has been led, in recent weeks, by France — and French AI startup Mistral, which had been lobbying for a total carve out from obligations for foundational models/GPAIs. In the event the deal agreed by the Spanish presidency does contain some obligations for GPAIs and foundation models. So it’s not the total carve out Mistral and its lobbyists have been pushing for.
Responding to news of the political deal last night, France’s digital minister’s office put out a statement attributed to Jean-Noël Barrot which said (translated from French using AI): “We will be carefully analyzing the compromise reached today, and in the coming weeks we will ensure that the text preserves Europe’s ability to develop its own artificial intelligence technologies, and safeguards its strategic autonomy.”
It remains unclear how much of a carve out Mistral’s business might enjoy under the deal agreed.
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37423
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EU lawmakers bag late night deal on ‘global first’ AI rules
In the event the deal agreed by the Spanish presidency does contain some obligations for GPAIs and foundation models. So it’s not the total carve out Mistral and its lobbyists have been pushing for.
Responding to news of the political deal last night, France’s digital minister’s office put out a statement attributed to Jean-Noël Barrot which said (translated from French using AI): “We will be carefully analyzing the compromise reached today, and in the coming weeks we will ensure that the text preserves Europe’s ability to develop its own artificial intelligence technologies, and safeguards its strategic autonomy.”
It remains unclear how much of a carve out Mistral’s business might enjoy under the deal agreed. Asked about this during the press conference, Artigas suggested the French AI startup would — once commercialized — be likely to fit in the “low tier” for GPAIs, meaning it would have only limited transparency obligations, since she said it does not hit the high capacity compute threshold triggering the systemic risk obligations (as she said it’s using what’s thought to be 10^23 of compute, not 10^25).
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37424
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EU lawmakers bag late night deal on ‘global first’ AI rules
Responding to news of the political deal last night, France’s digital minister’s office put out a statement attributed to Jean-Noël Barrot which said (translated from French using AI): “We will be carefully analyzing the compromise reached today, and in the coming weeks we will ensure that the text preserves Europe’s ability to develop its own artificial intelligence technologies, and safeguards its strategic autonomy.”
It remains unclear how much of a carve out Mistral’s business might enjoy under the deal agreed. Asked about this during the press conference, Artigas suggested the French AI startup would — once commercialized — be likely to fit in the “low tier” for GPAIs, meaning it would have only limited transparency obligations, since she said it does not hit the high capacity compute threshold triggering the systemic risk obligations (as she said it’s using what’s thought to be 10^23 of compute, not 10^25).
However, as Mistral is currently still in an R&D and pre-training phase for their models, she said they would be excluded from even the low tier compliance requirements.
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37425
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EU lawmakers bag late night deal on ‘global first’ AI rules
Asked about this during the press conference, Artigas suggested the French AI startup would — once commercialized — be likely to fit in the “low tier” for GPAIs, meaning it would have only limited transparency obligations, since she said it does not hit the high capacity compute threshold triggering the systemic risk obligations (as she said it’s using what’s thought to be 10^23 of compute, not 10^25).
However, as Mistral is currently still in an R&D and pre-training phase for their models, she said they would be excluded from even the low tier compliance requirements.
This report was updated to include the response from the French digital ministry; link to the Council’s PR; and with additional details from the presser — including remarks about how the law might apply to Mistral. We also added details on civil society’s response
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37426
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Mysterious dog respiratory illness: What to know
The mysterious respiratory illness that may have sickened scores of dogs across the country could be caused by a new type of bacterial infection that may be very good at evading the canine immune system, researchers say. Some dogs have died from the illness, which starts with causes a cough that can last for weeks, runny eyes and sneezing.
In a development that might help shed light on the illness, which has affected a variety of dog breeds, researchers at the University of New Hampshire’s Veterinary Diagnosis Laboratory and the Hubbard Center for Genome Studies told NBC News they have identified a pathogen that might be what’s making pets sick.
Through a genetic sequencing of samples from an initial group of 30 dogs from New Hampshire who were infected last year and then an additional 40 from Rhode Island and Massachusetts who got sick this year, the researchers say they have discovered a previously unknown germ.
The pathogen is “a funky bacterium,” said Dr. David Needle, pathology section chief at the College of Life Sciences and Agriculture at the University of New Hampshire.
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37427
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Mysterious dog respiratory illness: What to know
Some dogs have died from the illness, which starts with causes a cough that can last for weeks, runny eyes and sneezing.
In a development that might help shed light on the illness, which has affected a variety of dog breeds, researchers at the University of New Hampshire’s Veterinary Diagnosis Laboratory and the Hubbard Center for Genome Studies told NBC News they have identified a pathogen that might be what’s making pets sick.
Through a genetic sequencing of samples from an initial group of 30 dogs from New Hampshire who were infected last year and then an additional 40 from Rhode Island and Massachusetts who got sick this year, the researchers say they have discovered a previously unknown germ.
The pathogen is “a funky bacterium,” said Dr. David Needle, pathology section chief at the College of Life Sciences and Agriculture at the University of New Hampshire. “It’s smaller than a normal bacterium in its size and in the size of its genome.
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37428
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Mysterious dog respiratory illness: What to know
Some dogs have died from the illness, which starts with causes a cough that can last for weeks, runny eyes and sneezing.
In a development that might help shed light on the illness, which has affected a variety of dog breeds, researchers at the University of New Hampshire’s Veterinary Diagnosis Laboratory and the Hubbard Center for Genome Studies told NBC News they have identified a pathogen that might be what’s making pets sick.
Through a genetic sequencing of samples from an initial group of 30 dogs from New Hampshire who were infected last year and then an additional 40 from Rhode Island and Massachusetts who got sick this year, the researchers say they have discovered a previously unknown germ.
The pathogen is “a funky bacterium,” said Dr. David Needle, pathology section chief at the College of Life Sciences and Agriculture at the University of New Hampshire. “It’s smaller than a normal bacterium in its size and in the size of its genome. Long story short, it’s a weird bacterium that can be tough to find and sequence.”
The germ “is new as a potential cause of disease, but it is likely to be— or to have evolved from — a component of the dog microbiome,” he said.
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37429
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Mysterious dog respiratory illness: What to know
Through a genetic sequencing of samples from an initial group of 30 dogs from New Hampshire who were infected last year and then an additional 40 from Rhode Island and Massachusetts who got sick this year, the researchers say they have discovered a previously unknown germ.
The pathogen is “a funky bacterium,” said Dr. David Needle, pathology section chief at the College of Life Sciences and Agriculture at the University of New Hampshire. “It’s smaller than a normal bacterium in its size and in the size of its genome. Long story short, it’s a weird bacterium that can be tough to find and sequence.”
The germ “is new as a potential cause of disease, but it is likely to be— or to have evolved from — a component of the dog microbiome,” he said. Dogs as well as humans have multiple types of harmless bacteria and other microorganisms living both inside and outside the body. In the gut, they are thought to aid in digestion.
The bacterium was discovered after a painstaking search.
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37430
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Mysterious dog respiratory illness: What to know
The pathogen is “a funky bacterium,” said Dr. David Needle, pathology section chief at the College of Life Sciences and Agriculture at the University of New Hampshire. “It’s smaller than a normal bacterium in its size and in the size of its genome. Long story short, it’s a weird bacterium that can be tough to find and sequence.”
The germ “is new as a potential cause of disease, but it is likely to be— or to have evolved from — a component of the dog microbiome,” he said. Dogs as well as humans have multiple types of harmless bacteria and other microorganisms living both inside and outside the body. In the gut, they are thought to aid in digestion.
The bacterium was discovered after a painstaking search.
“After initial sequencing showed there were no known viral, bacterial or fungal pathogens, time consuming and dogged work by graduate student Lawrence Gordon showed that 21 of the initial 30 samples from New Hampshire had some genetic material from one atypical bacterial species,” Needle said.
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37431
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Mysterious dog respiratory illness: What to know
David Needle, pathology section chief at the College of Life Sciences and Agriculture at the University of New Hampshire. “It’s smaller than a normal bacterium in its size and in the size of its genome. Long story short, it’s a weird bacterium that can be tough to find and sequence.”
The germ “is new as a potential cause of disease, but it is likely to be— or to have evolved from — a component of the dog microbiome,” he said. Dogs as well as humans have multiple types of harmless bacteria and other microorganisms living both inside and outside the body. In the gut, they are thought to aid in digestion.
The bacterium was discovered after a painstaking search.
“After initial sequencing showed there were no known viral, bacterial or fungal pathogens, time consuming and dogged work by graduate student Lawrence Gordon showed that 21 of the initial 30 samples from New Hampshire had some genetic material from one atypical bacterial species,” Needle said.
The UNH team is sharing its results prior to publishing a research article, hoping they will give veterinarians some information as they deal with other respiratory syndrome outbreaks, he said.
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37432
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Mysterious dog respiratory illness: What to know
Long story short, it’s a weird bacterium that can be tough to find and sequence.”
The germ “is new as a potential cause of disease, but it is likely to be— or to have evolved from — a component of the dog microbiome,” he said. Dogs as well as humans have multiple types of harmless bacteria and other microorganisms living both inside and outside the body. In the gut, they are thought to aid in digestion.
The bacterium was discovered after a painstaking search.
“After initial sequencing showed there were no known viral, bacterial or fungal pathogens, time consuming and dogged work by graduate student Lawrence Gordon showed that 21 of the initial 30 samples from New Hampshire had some genetic material from one atypical bacterial species,” Needle said.
The UNH team is sharing its results prior to publishing a research article, hoping they will give veterinarians some information as they deal with other respiratory syndrome outbreaks, he said.
Scientists aren’t even sure yet whether the same bug is making dogs sick across the nation.
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37433
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Mysterious dog respiratory illness: What to know
Dogs as well as humans have multiple types of harmless bacteria and other microorganisms living both inside and outside the body. In the gut, they are thought to aid in digestion.
The bacterium was discovered after a painstaking search.
“After initial sequencing showed there were no known viral, bacterial or fungal pathogens, time consuming and dogged work by graduate student Lawrence Gordon showed that 21 of the initial 30 samples from New Hampshire had some genetic material from one atypical bacterial species,” Needle said.
The UNH team is sharing its results prior to publishing a research article, hoping they will give veterinarians some information as they deal with other respiratory syndrome outbreaks, he said.
Scientists aren’t even sure yet whether the same bug is making dogs sick across the nation. Many researchers have wondered whether it was a bacterial or a viral pathogen. One thing veterinarians do know is that the germ is something they don’t recognize.
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37434
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Mysterious dog respiratory illness: What to know
Dogs as well as humans have multiple types of harmless bacteria and other microorganisms living both inside and outside the body. In the gut, they are thought to aid in digestion.
The bacterium was discovered after a painstaking search.
“After initial sequencing showed there were no known viral, bacterial or fungal pathogens, time consuming and dogged work by graduate student Lawrence Gordon showed that 21 of the initial 30 samples from New Hampshire had some genetic material from one atypical bacterial species,” Needle said.
The UNH team is sharing its results prior to publishing a research article, hoping they will give veterinarians some information as they deal with other respiratory syndrome outbreaks, he said.
Scientists aren’t even sure yet whether the same bug is making dogs sick across the nation. Many researchers have wondered whether it was a bacterial or a viral pathogen. One thing veterinarians do know is that the germ is something they don’t recognize.
Mike Stepien, a spokesperson for the USDA Animal and Plant Health Inspection Service (APHIS), said in an email Wednesday the agency is working with multiple state animal health officials and diagnostic labs regarding the respiratory illness in dogs that, "in rare cases, has progressed rapidly to death."
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37435
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Mysterious dog respiratory illness: What to know
“After initial sequencing showed there were no known viral, bacterial or fungal pathogens, time consuming and dogged work by graduate student Lawrence Gordon showed that 21 of the initial 30 samples from New Hampshire had some genetic material from one atypical bacterial species,” Needle said.
The UNH team is sharing its results prior to publishing a research article, hoping they will give veterinarians some information as they deal with other respiratory syndrome outbreaks, he said.
Scientists aren’t even sure yet whether the same bug is making dogs sick across the nation. Many researchers have wondered whether it was a bacterial or a viral pathogen. One thing veterinarians do know is that the germ is something they don’t recognize.
Mike Stepien, a spokesperson for the USDA Animal and Plant Health Inspection Service (APHIS), said in an email Wednesday the agency is working with multiple state animal health officials and diagnostic labs regarding the respiratory illness in dogs that, "in rare cases, has progressed rapidly to death."
"APHIS and partners have not yet definitively identified the cause of illness," Stepien responded in an email.
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37436
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Mysterious dog respiratory illness: What to know
The UNH team is sharing its results prior to publishing a research article, hoping they will give veterinarians some information as they deal with other respiratory syndrome outbreaks, he said.
Scientists aren’t even sure yet whether the same bug is making dogs sick across the nation. Many researchers have wondered whether it was a bacterial or a viral pathogen. One thing veterinarians do know is that the germ is something they don’t recognize.
Mike Stepien, a spokesperson for the USDA Animal and Plant Health Inspection Service (APHIS), said in an email Wednesday the agency is working with multiple state animal health officials and diagnostic labs regarding the respiratory illness in dogs that, "in rare cases, has progressed rapidly to death."
"APHIS and partners have not yet definitively identified the cause of illness," Stepien responded in an email. "There are no reports of human illness affiliated with these cases at this time."
New Hampshire is one of a handful of states that have reported cases of the respiratory infection in dogs.
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37437
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Mysterious dog respiratory illness: What to know
Scientists aren’t even sure yet whether the same bug is making dogs sick across the nation. Many researchers have wondered whether it was a bacterial or a viral pathogen. One thing veterinarians do know is that the germ is something they don’t recognize.
Mike Stepien, a spokesperson for the USDA Animal and Plant Health Inspection Service (APHIS), said in an email Wednesday the agency is working with multiple state animal health officials and diagnostic labs regarding the respiratory illness in dogs that, "in rare cases, has progressed rapidly to death."
"APHIS and partners have not yet definitively identified the cause of illness," Stepien responded in an email. "There are no reports of human illness affiliated with these cases at this time."
New Hampshire is one of a handful of states that have reported cases of the respiratory infection in dogs.
The Oregon Agriculture Department has received more than 200 case reports from veterinarians around the state since the beginning of August, spokesperson Andrea Cantu-Schomus said in an email.
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37438
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Mysterious dog respiratory illness: What to know
Many researchers have wondered whether it was a bacterial or a viral pathogen. One thing veterinarians do know is that the germ is something they don’t recognize.
Mike Stepien, a spokesperson for the USDA Animal and Plant Health Inspection Service (APHIS), said in an email Wednesday the agency is working with multiple state animal health officials and diagnostic labs regarding the respiratory illness in dogs that, "in rare cases, has progressed rapidly to death."
"APHIS and partners have not yet definitively identified the cause of illness," Stepien responded in an email. "There are no reports of human illness affiliated with these cases at this time."
New Hampshire is one of a handful of states that have reported cases of the respiratory infection in dogs.
The Oregon Agriculture Department has received more than 200 case reports from veterinarians around the state since the beginning of August, spokesperson Andrea Cantu-Schomus said in an email. A very small percentage of the dogs have died, Cantu-Schomus said.
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37439
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Mysterious dog respiratory illness: What to know
One thing veterinarians do know is that the germ is something they don’t recognize.
Mike Stepien, a spokesperson for the USDA Animal and Plant Health Inspection Service (APHIS), said in an email Wednesday the agency is working with multiple state animal health officials and diagnostic labs regarding the respiratory illness in dogs that, "in rare cases, has progressed rapidly to death."
"APHIS and partners have not yet definitively identified the cause of illness," Stepien responded in an email. "There are no reports of human illness affiliated with these cases at this time."
New Hampshire is one of a handful of states that have reported cases of the respiratory infection in dogs.
The Oregon Agriculture Department has received more than 200 case reports from veterinarians around the state since the beginning of August, spokesperson Andrea Cantu-Schomus said in an email. A very small percentage of the dogs have died, Cantu-Schomus said.
Other states with possible cases include:
In conversations with veterinarians, Dr.
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37440
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Mysterious dog respiratory illness: What to know
Mike Stepien, a spokesperson for the USDA Animal and Plant Health Inspection Service (APHIS), said in an email Wednesday the agency is working with multiple state animal health officials and diagnostic labs regarding the respiratory illness in dogs that, "in rare cases, has progressed rapidly to death."
"APHIS and partners have not yet definitively identified the cause of illness," Stepien responded in an email. "There are no reports of human illness affiliated with these cases at this time."
New Hampshire is one of a handful of states that have reported cases of the respiratory infection in dogs.
The Oregon Agriculture Department has received more than 200 case reports from veterinarians around the state since the beginning of August, spokesperson Andrea Cantu-Schomus said in an email. A very small percentage of the dogs have died, Cantu-Schomus said.
Other states with possible cases include:
In conversations with veterinarians, Dr. Karl E. Jandrey, a professor of clinical small animal emergency and critical care at the University of California, Davis, School of Veterinary Medicine, has heard of potential cases in North Carolina, Rhode Island and Virginia, as well.
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37441
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Mysterious dog respiratory illness: What to know
"APHIS and partners have not yet definitively identified the cause of illness," Stepien responded in an email. "There are no reports of human illness affiliated with these cases at this time."
New Hampshire is one of a handful of states that have reported cases of the respiratory infection in dogs.
The Oregon Agriculture Department has received more than 200 case reports from veterinarians around the state since the beginning of August, spokesperson Andrea Cantu-Schomus said in an email. A very small percentage of the dogs have died, Cantu-Schomus said.
Other states with possible cases include:
In conversations with veterinarians, Dr. Karl E. Jandrey, a professor of clinical small animal emergency and critical care at the University of California, Davis, School of Veterinary Medicine, has heard of potential cases in North Carolina, Rhode Island and Virginia, as well.
Because there is no test yet for the illness and because many of the symptoms are similar to other respiratory infections, such as canine influenza and Bordetella (kennel cough), it’s unknown exactly how many dogs have been affected.
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37442
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Mysterious dog respiratory illness: What to know
New Hampshire is one of a handful of states that have reported cases of the respiratory infection in dogs.
The Oregon Agriculture Department has received more than 200 case reports from veterinarians around the state since the beginning of August, spokesperson Andrea Cantu-Schomus said in an email. A very small percentage of the dogs have died, Cantu-Schomus said.
Other states with possible cases include:
In conversations with veterinarians, Dr. Karl E. Jandrey, a professor of clinical small animal emergency and critical care at the University of California, Davis, School of Veterinary Medicine, has heard of potential cases in North Carolina, Rhode Island and Virginia, as well.
Because there is no test yet for the illness and because many of the symptoms are similar to other respiratory infections, such as canine influenza and Bordetella (kennel cough), it’s unknown exactly how many dogs have been affected. With hundreds of cases identified by symptoms reported only in Oregon, it’s likely there are thousands.
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37443
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Mysterious dog respiratory illness: What to know
The Oregon Agriculture Department has received more than 200 case reports from veterinarians around the state since the beginning of August, spokesperson Andrea Cantu-Schomus said in an email. A very small percentage of the dogs have died, Cantu-Schomus said.
Other states with possible cases include:
In conversations with veterinarians, Dr. Karl E. Jandrey, a professor of clinical small animal emergency and critical care at the University of California, Davis, School of Veterinary Medicine, has heard of potential cases in North Carolina, Rhode Island and Virginia, as well.
Because there is no test yet for the illness and because many of the symptoms are similar to other respiratory infections, such as canine influenza and Bordetella (kennel cough), it’s unknown exactly how many dogs have been affected. With hundreds of cases identified by symptoms reported only in Oregon, it’s likely there are thousands.
Normally, to determine what antibiotics might work best against a particular type of bacteria, labs grow the bugs in a petri dish and then try to kill them with various medications.
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37444
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Mysterious dog respiratory illness: What to know
A very small percentage of the dogs have died, Cantu-Schomus said.
Other states with possible cases include:
In conversations with veterinarians, Dr. Karl E. Jandrey, a professor of clinical small animal emergency and critical care at the University of California, Davis, School of Veterinary Medicine, has heard of potential cases in North Carolina, Rhode Island and Virginia, as well.
Because there is no test yet for the illness and because many of the symptoms are similar to other respiratory infections, such as canine influenza and Bordetella (kennel cough), it’s unknown exactly how many dogs have been affected. With hundreds of cases identified by symptoms reported only in Oregon, it’s likely there are thousands.
Normally, to determine what antibiotics might work best against a particular type of bacteria, labs grow the bugs in a petri dish and then try to kill them with various medications. Needle and his colleagues have not been able to grow the new bacteria in the lab.
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37445
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Mysterious dog respiratory illness: What to know
Other states with possible cases include:
In conversations with veterinarians, Dr. Karl E. Jandrey, a professor of clinical small animal emergency and critical care at the University of California, Davis, School of Veterinary Medicine, has heard of potential cases in North Carolina, Rhode Island and Virginia, as well.
Because there is no test yet for the illness and because many of the symptoms are similar to other respiratory infections, such as canine influenza and Bordetella (kennel cough), it’s unknown exactly how many dogs have been affected. With hundreds of cases identified by symptoms reported only in Oregon, it’s likely there are thousands.
Normally, to determine what antibiotics might work best against a particular type of bacteria, labs grow the bugs in a petri dish and then try to kill them with various medications. Needle and his colleagues have not been able to grow the new bacteria in the lab. Nevertheless, its structure offers some clues about which medications might be the best choice to fight it, he said.
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37446
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Mysterious dog respiratory illness: What to know
Karl E. Jandrey, a professor of clinical small animal emergency and critical care at the University of California, Davis, School of Veterinary Medicine, has heard of potential cases in North Carolina, Rhode Island and Virginia, as well.
Because there is no test yet for the illness and because many of the symptoms are similar to other respiratory infections, such as canine influenza and Bordetella (kennel cough), it’s unknown exactly how many dogs have been affected. With hundreds of cases identified by symptoms reported only in Oregon, it’s likely there are thousands.
Normally, to determine what antibiotics might work best against a particular type of bacteria, labs grow the bugs in a petri dish and then try to kill them with various medications. Needle and his colleagues have not been able to grow the new bacteria in the lab. Nevertheless, its structure offers some clues about which medications might be the best choice to fight it, he said. The antibiotic doxycycline may be effective, he suggested.
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37447
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Mysterious dog respiratory illness: What to know
Because there is no test yet for the illness and because many of the symptoms are similar to other respiratory infections, such as canine influenza and Bordetella (kennel cough), it’s unknown exactly how many dogs have been affected. With hundreds of cases identified by symptoms reported only in Oregon, it’s likely there are thousands.
Normally, to determine what antibiotics might work best against a particular type of bacteria, labs grow the bugs in a petri dish and then try to kill them with various medications. Needle and his colleagues have not been able to grow the new bacteria in the lab. Nevertheless, its structure offers some clues about which medications might be the best choice to fight it, he said. The antibiotic doxycycline may be effective, he suggested.
If it turns out that the New Hampshire researchers have found the right microbe, that may explain why some dogs are getting very sick, said Jandrey.
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37448
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Mysterious dog respiratory illness: What to know
Because there is no test yet for the illness and because many of the symptoms are similar to other respiratory infections, such as canine influenza and Bordetella (kennel cough), it’s unknown exactly how many dogs have been affected. With hundreds of cases identified by symptoms reported only in Oregon, it’s likely there are thousands.
Normally, to determine what antibiotics might work best against a particular type of bacteria, labs grow the bugs in a petri dish and then try to kill them with various medications. Needle and his colleagues have not been able to grow the new bacteria in the lab. Nevertheless, its structure offers some clues about which medications might be the best choice to fight it, he said. The antibiotic doxycycline may be effective, he suggested.
If it turns out that the New Hampshire researchers have found the right microbe, that may explain why some dogs are getting very sick, said Jandrey.
Smaller pathogens are likely to have an easier time making it past a dog’s defenses in the upper respiratory tract and getting down into the lungs, he said.
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37449
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Mysterious dog respiratory illness: What to know
With hundreds of cases identified by symptoms reported only in Oregon, it’s likely there are thousands.
Normally, to determine what antibiotics might work best against a particular type of bacteria, labs grow the bugs in a petri dish and then try to kill them with various medications. Needle and his colleagues have not been able to grow the new bacteria in the lab. Nevertheless, its structure offers some clues about which medications might be the best choice to fight it, he said. The antibiotic doxycycline may be effective, he suggested.
If it turns out that the New Hampshire researchers have found the right microbe, that may explain why some dogs are getting very sick, said Jandrey.
Smaller pathogens are likely to have an easier time making it past a dog’s defenses in the upper respiratory tract and getting down into the lungs, he said. “If it goes into the lungs, there’s a risk of pneumonia,” he added.
What are the dog infection symptoms?
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Mysterious dog respiratory illness: What to know
With hundreds of cases identified by symptoms reported only in Oregon, it’s likely there are thousands.
Normally, to determine what antibiotics might work best against a particular type of bacteria, labs grow the bugs in a petri dish and then try to kill them with various medications. Needle and his colleagues have not been able to grow the new bacteria in the lab. Nevertheless, its structure offers some clues about which medications might be the best choice to fight it, he said. The antibiotic doxycycline may be effective, he suggested.
If it turns out that the New Hampshire researchers have found the right microbe, that may explain why some dogs are getting very sick, said Jandrey.
Smaller pathogens are likely to have an easier time making it past a dog’s defenses in the upper respiratory tract and getting down into the lungs, he said. “If it goes into the lungs, there’s a risk of pneumonia,” he added.
What are the dog infection symptoms?
According to Oregon’s Cantu-Schomus, the dogs’ illnesses largely develop in three ways:
As an inflammation of the tubes that connect the throat to the lungs that is minimally or not responsive to antibiotics.
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37451
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Mysterious dog respiratory illness: What to know
Needle and his colleagues have not been able to grow the new bacteria in the lab. Nevertheless, its structure offers some clues about which medications might be the best choice to fight it, he said. The antibiotic doxycycline may be effective, he suggested.
If it turns out that the New Hampshire researchers have found the right microbe, that may explain why some dogs are getting very sick, said Jandrey.
Smaller pathogens are likely to have an easier time making it past a dog’s defenses in the upper respiratory tract and getting down into the lungs, he said. “If it goes into the lungs, there’s a risk of pneumonia,” he added.
What are the dog infection symptoms?
According to Oregon’s Cantu-Schomus, the dogs’ illnesses largely develop in three ways:
As an inflammation of the tubes that connect the throat to the lungs that is minimally or not responsive to antibiotics.
As chronic pneumonia that is minimally or not responsive to antibiotics.
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37452
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Mysterious dog respiratory illness: What to know
Nevertheless, its structure offers some clues about which medications might be the best choice to fight it, he said. The antibiotic doxycycline may be effective, he suggested.
If it turns out that the New Hampshire researchers have found the right microbe, that may explain why some dogs are getting very sick, said Jandrey.
Smaller pathogens are likely to have an easier time making it past a dog’s defenses in the upper respiratory tract and getting down into the lungs, he said. “If it goes into the lungs, there’s a risk of pneumonia,” he added.
What are the dog infection symptoms?
According to Oregon’s Cantu-Schomus, the dogs’ illnesses largely develop in three ways:
As an inflammation of the tubes that connect the throat to the lungs that is minimally or not responsive to antibiotics.
As chronic pneumonia that is minimally or not responsive to antibiotics.
As acute pneumonia that rapidly becomes severe and often leads to severe illness or possibly death in as little as 24 to 36 hours.
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37453
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Mysterious dog respiratory illness: What to know
The antibiotic doxycycline may be effective, he suggested.
If it turns out that the New Hampshire researchers have found the right microbe, that may explain why some dogs are getting very sick, said Jandrey.
Smaller pathogens are likely to have an easier time making it past a dog’s defenses in the upper respiratory tract and getting down into the lungs, he said. “If it goes into the lungs, there’s a risk of pneumonia,” he added.
What are the dog infection symptoms?
According to Oregon’s Cantu-Schomus, the dogs’ illnesses largely develop in three ways:
As an inflammation of the tubes that connect the throat to the lungs that is minimally or not responsive to antibiotics.
As chronic pneumonia that is minimally or not responsive to antibiotics.
As acute pneumonia that rapidly becomes severe and often leads to severe illness or possibly death in as little as 24 to 36 hours.
If a dog has a cough that won’t quit and other respiratory symptoms, it’s recommended that the owner contact a veterinarian right away.
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37454
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Mysterious dog respiratory illness: What to know
If it turns out that the New Hampshire researchers have found the right microbe, that may explain why some dogs are getting very sick, said Jandrey.
Smaller pathogens are likely to have an easier time making it past a dog’s defenses in the upper respiratory tract and getting down into the lungs, he said. “If it goes into the lungs, there’s a risk of pneumonia,” he added.
What are the dog infection symptoms?
According to Oregon’s Cantu-Schomus, the dogs’ illnesses largely develop in three ways:
As an inflammation of the tubes that connect the throat to the lungs that is minimally or not responsive to antibiotics.
As chronic pneumonia that is minimally or not responsive to antibiotics.
As acute pneumonia that rapidly becomes severe and often leads to severe illness or possibly death in as little as 24 to 36 hours.
If a dog has a cough that won’t quit and other respiratory symptoms, it’s recommended that the owner contact a veterinarian right away.
While the respiratory symptoms seem to be like a viral illness, testing has been negative for a virus, Cantu-Schomus said.
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37455
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Mysterious dog respiratory illness: What to know
Smaller pathogens are likely to have an easier time making it past a dog’s defenses in the upper respiratory tract and getting down into the lungs, he said. “If it goes into the lungs, there’s a risk of pneumonia,” he added.
What are the dog infection symptoms?
According to Oregon’s Cantu-Schomus, the dogs’ illnesses largely develop in three ways:
As an inflammation of the tubes that connect the throat to the lungs that is minimally or not responsive to antibiotics.
As chronic pneumonia that is minimally or not responsive to antibiotics.
As acute pneumonia that rapidly becomes severe and often leads to severe illness or possibly death in as little as 24 to 36 hours.
If a dog has a cough that won’t quit and other respiratory symptoms, it’s recommended that the owner contact a veterinarian right away.
While the respiratory symptoms seem to be like a viral illness, testing has been negative for a virus, Cantu-Schomus said.
It’s very unlikely that the cause will turn out to be viral, said Colin Parrish, a professor of virology at the College of Veterinary Medicine at Cornell University.
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37456
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Mysterious dog respiratory illness: What to know
“If it goes into the lungs, there’s a risk of pneumonia,” he added.
What are the dog infection symptoms?
According to Oregon’s Cantu-Schomus, the dogs’ illnesses largely develop in three ways:
As an inflammation of the tubes that connect the throat to the lungs that is minimally or not responsive to antibiotics.
As chronic pneumonia that is minimally or not responsive to antibiotics.
As acute pneumonia that rapidly becomes severe and often leads to severe illness or possibly death in as little as 24 to 36 hours.
If a dog has a cough that won’t quit and other respiratory symptoms, it’s recommended that the owner contact a veterinarian right away.
While the respiratory symptoms seem to be like a viral illness, testing has been negative for a virus, Cantu-Schomus said.
It’s very unlikely that the cause will turn out to be viral, said Colin Parrish, a professor of virology at the College of Veterinary Medicine at Cornell University. “With the sequencing methods people use to look for unknown viruses, its signature would have been clear in a few days,” he added.
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37457
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Mysterious dog respiratory illness: What to know
As chronic pneumonia that is minimally or not responsive to antibiotics.
As acute pneumonia that rapidly becomes severe and often leads to severe illness or possibly death in as little as 24 to 36 hours.
If a dog has a cough that won’t quit and other respiratory symptoms, it’s recommended that the owner contact a veterinarian right away.
While the respiratory symptoms seem to be like a viral illness, testing has been negative for a virus, Cantu-Schomus said.
It’s very unlikely that the cause will turn out to be viral, said Colin Parrish, a professor of virology at the College of Veterinary Medicine at Cornell University. “With the sequencing methods people use to look for unknown viruses, its signature would have been clear in a few days,” he added.
So it’s possible that the New Hampshire scientists could have hit upon the right pathogen, although their results need to be confirmed by more research, he said.
What owners should do
The American Kennel Club’s chief veterinarian offered advice for both dog owners and their vets.
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37458
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Mysterious dog respiratory illness: What to know
As acute pneumonia that rapidly becomes severe and often leads to severe illness or possibly death in as little as 24 to 36 hours.
If a dog has a cough that won’t quit and other respiratory symptoms, it’s recommended that the owner contact a veterinarian right away.
While the respiratory symptoms seem to be like a viral illness, testing has been negative for a virus, Cantu-Schomus said.
It’s very unlikely that the cause will turn out to be viral, said Colin Parrish, a professor of virology at the College of Veterinary Medicine at Cornell University. “With the sequencing methods people use to look for unknown viruses, its signature would have been clear in a few days,” he added.
So it’s possible that the New Hampshire scientists could have hit upon the right pathogen, although their results need to be confirmed by more research, he said.
What owners should do
The American Kennel Club’s chief veterinarian offered advice for both dog owners and their vets.
First, owners should make sure their pets are fully vaccinated and boosted against the known canine diseases, said Dr.
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37459
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Mysterious dog respiratory illness: What to know
If a dog has a cough that won’t quit and other respiratory symptoms, it’s recommended that the owner contact a veterinarian right away.
While the respiratory symptoms seem to be like a viral illness, testing has been negative for a virus, Cantu-Schomus said.
It’s very unlikely that the cause will turn out to be viral, said Colin Parrish, a professor of virology at the College of Veterinary Medicine at Cornell University. “With the sequencing methods people use to look for unknown viruses, its signature would have been clear in a few days,” he added.
So it’s possible that the New Hampshire scientists could have hit upon the right pathogen, although their results need to be confirmed by more research, he said.
What owners should do
The American Kennel Club’s chief veterinarian offered advice for both dog owners and their vets.
First, owners should make sure their pets are fully vaccinated and boosted against the known canine diseases, said Dr. Jerry Klein, a practicing vet for 35 years and who was emergency department head emeritus at MedVet Chicago and currently works at the McKillip Animal Hospital in Chicago.
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Mysterious dog respiratory illness: What to know
It’s very unlikely that the cause will turn out to be viral, said Colin Parrish, a professor of virology at the College of Veterinary Medicine at Cornell University. “With the sequencing methods people use to look for unknown viruses, its signature would have been clear in a few days,” he added.
So it’s possible that the New Hampshire scientists could have hit upon the right pathogen, although their results need to be confirmed by more research, he said.
What owners should do
The American Kennel Club’s chief veterinarian offered advice for both dog owners and their vets.
First, owners should make sure their pets are fully vaccinated and boosted against the known canine diseases, said Dr. Jerry Klein, a practicing vet for 35 years and who was emergency department head emeritus at MedVet Chicago and currently works at the McKillip Animal Hospital in Chicago.
Klein recommends that veterinarians suggest a full respiratory panel when people bring in sick dogs, but acknowledges that may be an expense some owners can’t afford.
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37461
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Mysterious dog respiratory illness: What to know
“With the sequencing methods people use to look for unknown viruses, its signature would have been clear in a few days,” he added.
So it’s possible that the New Hampshire scientists could have hit upon the right pathogen, although their results need to be confirmed by more research, he said.
What owners should do
The American Kennel Club’s chief veterinarian offered advice for both dog owners and their vets.
First, owners should make sure their pets are fully vaccinated and boosted against the known canine diseases, said Dr. Jerry Klein, a practicing vet for 35 years and who was emergency department head emeritus at MedVet Chicago and currently works at the McKillip Animal Hospital in Chicago.
Klein recommends that veterinarians suggest a full respiratory panel when people bring in sick dogs, but acknowledges that may be an expense some owners can’t afford.
If a dog’s veterinarian doesn’t suggest the panel, then owners should request it; that will help determine if the germ is one that vets already know about or is something new.
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37462
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Mysterious dog respiratory illness: What to know
So it’s possible that the New Hampshire scientists could have hit upon the right pathogen, although their results need to be confirmed by more research, he said.
What owners should do
The American Kennel Club’s chief veterinarian offered advice for both dog owners and their vets.
First, owners should make sure their pets are fully vaccinated and boosted against the known canine diseases, said Dr. Jerry Klein, a practicing vet for 35 years and who was emergency department head emeritus at MedVet Chicago and currently works at the McKillip Animal Hospital in Chicago.
Klein recommends that veterinarians suggest a full respiratory panel when people bring in sick dogs, but acknowledges that may be an expense some owners can’t afford.
If a dog’s veterinarian doesn’t suggest the panel, then owners should request it; that will help determine if the germ is one that vets already know about or is something new.
People can call their local emergency vets to find out if there has been an increase in respiratory infections coming in for treatment, Klein said.
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37463
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Mysterious dog respiratory illness: What to know
What owners should do
The American Kennel Club’s chief veterinarian offered advice for both dog owners and their vets.
First, owners should make sure their pets are fully vaccinated and boosted against the known canine diseases, said Dr. Jerry Klein, a practicing vet for 35 years and who was emergency department head emeritus at MedVet Chicago and currently works at the McKillip Animal Hospital in Chicago.
Klein recommends that veterinarians suggest a full respiratory panel when people bring in sick dogs, but acknowledges that may be an expense some owners can’t afford.
If a dog’s veterinarian doesn’t suggest the panel, then owners should request it; that will help determine if the germ is one that vets already know about or is something new.
People can call their local emergency vets to find out if there has been an increase in respiratory infections coming in for treatment, Klein said.
“That would be a way to find out whether there’s been an uptick in your area,” he said.
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37464
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Mysterious dog respiratory illness: What to know
What owners should do
The American Kennel Club’s chief veterinarian offered advice for both dog owners and their vets.
First, owners should make sure their pets are fully vaccinated and boosted against the known canine diseases, said Dr. Jerry Klein, a practicing vet for 35 years and who was emergency department head emeritus at MedVet Chicago and currently works at the McKillip Animal Hospital in Chicago.
Klein recommends that veterinarians suggest a full respiratory panel when people bring in sick dogs, but acknowledges that may be an expense some owners can’t afford.
If a dog’s veterinarian doesn’t suggest the panel, then owners should request it; that will help determine if the germ is one that vets already know about or is something new.
People can call their local emergency vets to find out if there has been an increase in respiratory infections coming in for treatment, Klein said.
“That would be a way to find out whether there’s been an uptick in your area,” he said. “If there is, then they should try to protect against exposure by avoiding grooming establishments and daycare.”
Klein also recommends that groomers and daycare facilities not allow dogs to share food and water dishes.
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37465
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Mysterious dog respiratory illness: What to know
Jerry Klein, a practicing vet for 35 years and who was emergency department head emeritus at MedVet Chicago and currently works at the McKillip Animal Hospital in Chicago.
Klein recommends that veterinarians suggest a full respiratory panel when people bring in sick dogs, but acknowledges that may be an expense some owners can’t afford.
If a dog’s veterinarian doesn’t suggest the panel, then owners should request it; that will help determine if the germ is one that vets already know about or is something new.
People can call their local emergency vets to find out if there has been an increase in respiratory infections coming in for treatment, Klein said.
“That would be a way to find out whether there’s been an uptick in your area,” he said. “If there is, then they should try to protect against exposure by avoiding grooming establishments and daycare.”
Klein also recommends that groomers and daycare facilities not allow dogs to share food and water dishes.
Even though a record number of Americans are expected to travel during the holiday season, experts recommend that dog owners keep their pets out of kennels and other areas, such as dog parks, where infection might be more likely because of crowded conditions and close contact.
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37466
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Mysterious dog respiratory illness: What to know
If a dog’s veterinarian doesn’t suggest the panel, then owners should request it; that will help determine if the germ is one that vets already know about or is something new.
People can call their local emergency vets to find out if there has been an increase in respiratory infections coming in for treatment, Klein said.
“That would be a way to find out whether there’s been an uptick in your area,” he said. “If there is, then they should try to protect against exposure by avoiding grooming establishments and daycare.”
Klein also recommends that groomers and daycare facilities not allow dogs to share food and water dishes.
Even though a record number of Americans are expected to travel during the holiday season, experts recommend that dog owners keep their pets out of kennels and other areas, such as dog parks, where infection might be more likely because of crowded conditions and close contact.
“When you congregate a bunch of animals together, there’s a larger likelihood of getting an infectious disease from other dogs,” said Dr.
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37467
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Mysterious dog respiratory illness: What to know
People can call their local emergency vets to find out if there has been an increase in respiratory infections coming in for treatment, Klein said.
“That would be a way to find out whether there’s been an uptick in your area,” he said. “If there is, then they should try to protect against exposure by avoiding grooming establishments and daycare.”
Klein also recommends that groomers and daycare facilities not allow dogs to share food and water dishes.
Even though a record number of Americans are expected to travel during the holiday season, experts recommend that dog owners keep their pets out of kennels and other areas, such as dog parks, where infection might be more likely because of crowded conditions and close contact.
“When you congregate a bunch of animals together, there’s a larger likelihood of getting an infectious disease from other dogs,” said Dr. Kurt Williams, director of the Oregon Veterinary Diagnostic Lab at the Carlson College of Veterinary Medicine at Oregon State University.
Still, he said, there are some facilities where you are less likely to have a problem because of how they are designed.
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37468
|
Mysterious dog respiratory illness: What to know
“That would be a way to find out whether there’s been an uptick in your area,” he said. “If there is, then they should try to protect against exposure by avoiding grooming establishments and daycare.”
Klein also recommends that groomers and daycare facilities not allow dogs to share food and water dishes.
Even though a record number of Americans are expected to travel during the holiday season, experts recommend that dog owners keep their pets out of kennels and other areas, such as dog parks, where infection might be more likely because of crowded conditions and close contact.
“When you congregate a bunch of animals together, there’s a larger likelihood of getting an infectious disease from other dogs,” said Dr. Kurt Williams, director of the Oregon Veterinary Diagnostic Lab at the Carlson College of Veterinary Medicine at Oregon State University.
Still, he said, there are some facilities where you are less likely to have a problem because of how they are designed.
“I’ve been telling people to work closely with their vet,” Williams said.
|
37469
|
Mysterious dog respiratory illness: What to know
“If there is, then they should try to protect against exposure by avoiding grooming establishments and daycare.”
Klein also recommends that groomers and daycare facilities not allow dogs to share food and water dishes.
Even though a record number of Americans are expected to travel during the holiday season, experts recommend that dog owners keep their pets out of kennels and other areas, such as dog parks, where infection might be more likely because of crowded conditions and close contact.
“When you congregate a bunch of animals together, there’s a larger likelihood of getting an infectious disease from other dogs,” said Dr. Kurt Williams, director of the Oregon Veterinary Diagnostic Lab at the Carlson College of Veterinary Medicine at Oregon State University.
Still, he said, there are some facilities where you are less likely to have a problem because of how they are designed.
“I’ve been telling people to work closely with their vet,” Williams said. “And to make sure their dog has all the vaccines available, in particular those for respiratory diseases we are familiar with.”
Another option is for owners to hire a house sitter, Needle said.
|
37470
|
Mysterious dog respiratory illness: What to know
Even though a record number of Americans are expected to travel during the holiday season, experts recommend that dog owners keep their pets out of kennels and other areas, such as dog parks, where infection might be more likely because of crowded conditions and close contact.
“When you congregate a bunch of animals together, there’s a larger likelihood of getting an infectious disease from other dogs,” said Dr. Kurt Williams, director of the Oregon Veterinary Diagnostic Lab at the Carlson College of Veterinary Medicine at Oregon State University.
Still, he said, there are some facilities where you are less likely to have a problem because of how they are designed.
“I’ve been telling people to work closely with their vet,” Williams said. “And to make sure their dog has all the vaccines available, in particular those for respiratory diseases we are familiar with.”
Another option is for owners to hire a house sitter, Needle said. “Or hire a dog walker,” he added. “It might not be perfect, but it’s better than nothing.
|
37471
|
Mysterious dog respiratory illness: What to know
“When you congregate a bunch of animals together, there’s a larger likelihood of getting an infectious disease from other dogs,” said Dr. Kurt Williams, director of the Oregon Veterinary Diagnostic Lab at the Carlson College of Veterinary Medicine at Oregon State University.
Still, he said, there are some facilities where you are less likely to have a problem because of how they are designed.
“I’ve been telling people to work closely with their vet,” Williams said. “And to make sure their dog has all the vaccines available, in particular those for respiratory diseases we are familiar with.”
Another option is for owners to hire a house sitter, Needle said. “Or hire a dog walker,” he added. “It might not be perfect, but it’s better than nothing. Also, you might want to consider having Thanksgiving at home.”
Ultimately, your dog might be happier at home with a house sitter or a dog walker stopping by multiple times during the day than going to a kennel, Jandrey said.
“It’s best to leave them in their own environment,” he added.
|
37472
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Mysterious dog respiratory illness: What to know
Kurt Williams, director of the Oregon Veterinary Diagnostic Lab at the Carlson College of Veterinary Medicine at Oregon State University.
Still, he said, there are some facilities where you are less likely to have a problem because of how they are designed.
“I’ve been telling people to work closely with their vet,” Williams said. “And to make sure their dog has all the vaccines available, in particular those for respiratory diseases we are familiar with.”
Another option is for owners to hire a house sitter, Needle said. “Or hire a dog walker,” he added. “It might not be perfect, but it’s better than nothing. Also, you might want to consider having Thanksgiving at home.”
Ultimately, your dog might be happier at home with a house sitter or a dog walker stopping by multiple times during the day than going to a kennel, Jandrey said.
“It’s best to leave them in their own environment,” he added.
This article was originally published on NBCNews.com
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37473
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Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
Bacteria's rising resistance to antibiotics is making the drugs obsolete. Scientists are fighting back with viruses (pictured), CRISPR, designer molecules and cell-slicing enzymes.
The bacteria may have entered her flesh along with shrapnel from the bomb detonated in Brussels Airport in 2016. Or perhaps the microbes hitched a ride on the surgical instruments used to treat her wounds. Either way, the "superbug" refused to be vanquished, despite years of antibiotic treatment.
The woman had survived a terrorist attack but was held hostage by drug-resistant Klebsiella pneumoniae, a bacterial strain often picked up by surgery patients in hospitals. Only by combining antibiotics with a new, experimental treatment did doctors finally rid her of the superbug .
Devastating drug-resistant bacterial infections like this one are all too common, and they represent an ever-growing threat to global health.
|
37474
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
Bacteria's rising resistance to antibiotics is making the drugs obsolete. Scientists are fighting back with viruses (pictured), CRISPR, designer molecules and cell-slicing enzymes.
The bacteria may have entered her flesh along with shrapnel from the bomb detonated in Brussels Airport in 2016. Or perhaps the microbes hitched a ride on the surgical instruments used to treat her wounds. Either way, the "superbug" refused to be vanquished, despite years of antibiotic treatment.
The woman had survived a terrorist attack but was held hostage by drug-resistant Klebsiella pneumoniae, a bacterial strain often picked up by surgery patients in hospitals. Only by combining antibiotics with a new, experimental treatment did doctors finally rid her of the superbug .
Devastating drug-resistant bacterial infections like this one are all too common, and they represent an ever-growing threat to global health. In 2019, antibiotic-resistant bacteria directly killed roughly 1.27 million people worldwide and contributed to an additional 3.68 million deaths.
|
37475
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
Scientists are fighting back with viruses (pictured), CRISPR, designer molecules and cell-slicing enzymes.
The bacteria may have entered her flesh along with shrapnel from the bomb detonated in Brussels Airport in 2016. Or perhaps the microbes hitched a ride on the surgical instruments used to treat her wounds. Either way, the "superbug" refused to be vanquished, despite years of antibiotic treatment.
The woman had survived a terrorist attack but was held hostage by drug-resistant Klebsiella pneumoniae, a bacterial strain often picked up by surgery patients in hospitals. Only by combining antibiotics with a new, experimental treatment did doctors finally rid her of the superbug .
Devastating drug-resistant bacterial infections like this one are all too common, and they represent an ever-growing threat to global health. In 2019, antibiotic-resistant bacteria directly killed roughly 1.27 million people worldwide and contributed to an additional 3.68 million deaths. In the U.S.
|
37476
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
The bacteria may have entered her flesh along with shrapnel from the bomb detonated in Brussels Airport in 2016. Or perhaps the microbes hitched a ride on the surgical instruments used to treat her wounds. Either way, the "superbug" refused to be vanquished, despite years of antibiotic treatment.
The woman had survived a terrorist attack but was held hostage by drug-resistant Klebsiella pneumoniae, a bacterial strain often picked up by surgery patients in hospitals. Only by combining antibiotics with a new, experimental treatment did doctors finally rid her of the superbug .
Devastating drug-resistant bacterial infections like this one are all too common, and they represent an ever-growing threat to global health. In 2019, antibiotic-resistant bacteria directly killed roughly 1.27 million people worldwide and contributed to an additional 3.68 million deaths. In the U.S. alone, drug-resistant bacteria and fungi together cause an estimated 2.8 million infections and 35,000 deaths each year.
|
37477
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
Or perhaps the microbes hitched a ride on the surgical instruments used to treat her wounds. Either way, the "superbug" refused to be vanquished, despite years of antibiotic treatment.
The woman had survived a terrorist attack but was held hostage by drug-resistant Klebsiella pneumoniae, a bacterial strain often picked up by surgery patients in hospitals. Only by combining antibiotics with a new, experimental treatment did doctors finally rid her of the superbug .
Devastating drug-resistant bacterial infections like this one are all too common, and they represent an ever-growing threat to global health. In 2019, antibiotic-resistant bacteria directly killed roughly 1.27 million people worldwide and contributed to an additional 3.68 million deaths. In the U.S. alone, drug-resistant bacteria and fungi together cause an estimated 2.8 million infections and 35,000 deaths each year.
And the problem is getting worse: Seven of the 18 concerning bacteria tracked by the Centers for Disease Control and Prevention (CDC) are becoming more resistant to common antibiotics considered essential for maintaining public health.
|
37478
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
The woman had survived a terrorist attack but was held hostage by drug-resistant Klebsiella pneumoniae, a bacterial strain often picked up by surgery patients in hospitals. Only by combining antibiotics with a new, experimental treatment did doctors finally rid her of the superbug .
Devastating drug-resistant bacterial infections like this one are all too common, and they represent an ever-growing threat to global health. In 2019, antibiotic-resistant bacteria directly killed roughly 1.27 million people worldwide and contributed to an additional 3.68 million deaths. In the U.S. alone, drug-resistant bacteria and fungi together cause an estimated 2.8 million infections and 35,000 deaths each year.
And the problem is getting worse: Seven of the 18 concerning bacteria tracked by the Centers for Disease Control and Prevention (CDC) are becoming more resistant to common antibiotics considered essential for maintaining public health. Meanwhile, drug companies have been slow to make new antibiotics capable of beating the microbes.
|
37479
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
Only by combining antibiotics with a new, experimental treatment did doctors finally rid her of the superbug .
Devastating drug-resistant bacterial infections like this one are all too common, and they represent an ever-growing threat to global health. In 2019, antibiotic-resistant bacteria directly killed roughly 1.27 million people worldwide and contributed to an additional 3.68 million deaths. In the U.S. alone, drug-resistant bacteria and fungi together cause an estimated 2.8 million infections and 35,000 deaths each year.
And the problem is getting worse: Seven of the 18 concerning bacteria tracked by the Centers for Disease Control and Prevention (CDC) are becoming more resistant to common antibiotics considered essential for maintaining public health. Meanwhile, drug companies have been slow to make new antibiotics capable of beating the microbes. Fewer than 30 antibiotics currently in the development pipeline target "priority" bacteria , as defined by the World Health Organization (WHO), and most of those drugs are still vulnerable to resistance, just like their predecessors.
|
37480
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
Devastating drug-resistant bacterial infections like this one are all too common, and they represent an ever-growing threat to global health. In 2019, antibiotic-resistant bacteria directly killed roughly 1.27 million people worldwide and contributed to an additional 3.68 million deaths. In the U.S. alone, drug-resistant bacteria and fungi together cause an estimated 2.8 million infections and 35,000 deaths each year.
And the problem is getting worse: Seven of the 18 concerning bacteria tracked by the Centers for Disease Control and Prevention (CDC) are becoming more resistant to common antibiotics considered essential for maintaining public health. Meanwhile, drug companies have been slow to make new antibiotics capable of beating the microbes. Fewer than 30 antibiotics currently in the development pipeline target "priority" bacteria , as defined by the World Health Organization (WHO), and most of those drugs are still vulnerable to resistance, just like their predecessors.
This table of select antibiotic-resistant bacteria demonstrates how rapidly important types of resistance developed after the approval and release of new antibiotics.
|
37481
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
In 2019, antibiotic-resistant bacteria directly killed roughly 1.27 million people worldwide and contributed to an additional 3.68 million deaths. In the U.S. alone, drug-resistant bacteria and fungi together cause an estimated 2.8 million infections and 35,000 deaths each year.
And the problem is getting worse: Seven of the 18 concerning bacteria tracked by the Centers for Disease Control and Prevention (CDC) are becoming more resistant to common antibiotics considered essential for maintaining public health. Meanwhile, drug companies have been slow to make new antibiotics capable of beating the microbes. Fewer than 30 antibiotics currently in the development pipeline target "priority" bacteria , as defined by the World Health Organization (WHO), and most of those drugs are still vulnerable to resistance, just like their predecessors.
This table of select antibiotic-resistant bacteria demonstrates how rapidly important types of resistance developed after the approval and release of new antibiotics. (Image credit: Centers for Disease Control and Prevention.
|
37482
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
In the U.S. alone, drug-resistant bacteria and fungi together cause an estimated 2.8 million infections and 35,000 deaths each year.
And the problem is getting worse: Seven of the 18 concerning bacteria tracked by the Centers for Disease Control and Prevention (CDC) are becoming more resistant to common antibiotics considered essential for maintaining public health. Meanwhile, drug companies have been slow to make new antibiotics capable of beating the microbes. Fewer than 30 antibiotics currently in the development pipeline target "priority" bacteria , as defined by the World Health Organization (WHO), and most of those drugs are still vulnerable to resistance, just like their predecessors.
This table of select antibiotic-resistant bacteria demonstrates how rapidly important types of resistance developed after the approval and release of new antibiotics. (Image credit: Centers for Disease Control and Prevention. Adapted by Live Science from the CDC's "Select Germs Showing Resistance Over Time" Fact Sheet.)
|
37483
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
In the U.S. alone, drug-resistant bacteria and fungi together cause an estimated 2.8 million infections and 35,000 deaths each year.
And the problem is getting worse: Seven of the 18 concerning bacteria tracked by the Centers for Disease Control and Prevention (CDC) are becoming more resistant to common antibiotics considered essential for maintaining public health. Meanwhile, drug companies have been slow to make new antibiotics capable of beating the microbes. Fewer than 30 antibiotics currently in the development pipeline target "priority" bacteria , as defined by the World Health Organization (WHO), and most of those drugs are still vulnerable to resistance, just like their predecessors.
This table of select antibiotic-resistant bacteria demonstrates how rapidly important types of resistance developed after the approval and release of new antibiotics. (Image credit: Centers for Disease Control and Prevention. Adapted by Live Science from the CDC's "Select Germs Showing Resistance Over Time" Fact Sheet.)
So some scientists are looking beyond traditional antibiotics for new weapons that won't fuel the rise of superbugs.
|
37484
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
And the problem is getting worse: Seven of the 18 concerning bacteria tracked by the Centers for Disease Control and Prevention (CDC) are becoming more resistant to common antibiotics considered essential for maintaining public health. Meanwhile, drug companies have been slow to make new antibiotics capable of beating the microbes. Fewer than 30 antibiotics currently in the development pipeline target "priority" bacteria , as defined by the World Health Organization (WHO), and most of those drugs are still vulnerable to resistance, just like their predecessors.
This table of select antibiotic-resistant bacteria demonstrates how rapidly important types of resistance developed after the approval and release of new antibiotics. (Image credit: Centers for Disease Control and Prevention. Adapted by Live Science from the CDC's "Select Germs Showing Resistance Over Time" Fact Sheet.)
So some scientists are looking beyond traditional antibiotics for new weapons that won't fuel the rise of superbugs. Their emerging arsenal features viruses that kill bacteria; CRISPR; and microbe-slaying molecules.
|
37485
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
Meanwhile, drug companies have been slow to make new antibiotics capable of beating the microbes. Fewer than 30 antibiotics currently in the development pipeline target "priority" bacteria , as defined by the World Health Organization (WHO), and most of those drugs are still vulnerable to resistance, just like their predecessors.
This table of select antibiotic-resistant bacteria demonstrates how rapidly important types of resistance developed after the approval and release of new antibiotics. (Image credit: Centers for Disease Control and Prevention. Adapted by Live Science from the CDC's "Select Germs Showing Resistance Over Time" Fact Sheet.)
So some scientists are looking beyond traditional antibiotics for new weapons that won't fuel the rise of superbugs. Their emerging arsenal features viruses that kill bacteria; CRISPR; and microbe-slaying molecules. They hope that these experimental treatments, some of which have been tested in patients, will kill superbugs without promoting resistance.
|
37486
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
Meanwhile, drug companies have been slow to make new antibiotics capable of beating the microbes. Fewer than 30 antibiotics currently in the development pipeline target "priority" bacteria , as defined by the World Health Organization (WHO), and most of those drugs are still vulnerable to resistance, just like their predecessors.
This table of select antibiotic-resistant bacteria demonstrates how rapidly important types of resistance developed after the approval and release of new antibiotics. (Image credit: Centers for Disease Control and Prevention. Adapted by Live Science from the CDC's "Select Germs Showing Resistance Over Time" Fact Sheet.)
So some scientists are looking beyond traditional antibiotics for new weapons that won't fuel the rise of superbugs. Their emerging arsenal features viruses that kill bacteria; CRISPR; and microbe-slaying molecules. They hope that these experimental treatments, some of which have been tested in patients, will kill superbugs without promoting resistance.
"The vision, for me, is that we move beyond antibiotics and really just see a much broader palate of options," Chase Beisel, leader of the RNA synthetic biology research group at the Helmholtz Institute for RNA-based Infection Research in Germany, told Live Science.
|
37487
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
This table of select antibiotic-resistant bacteria demonstrates how rapidly important types of resistance developed after the approval and release of new antibiotics. (Image credit: Centers for Disease Control and Prevention. Adapted by Live Science from the CDC's "Select Germs Showing Resistance Over Time" Fact Sheet.)
So some scientists are looking beyond traditional antibiotics for new weapons that won't fuel the rise of superbugs. Their emerging arsenal features viruses that kill bacteria; CRISPR; and microbe-slaying molecules. They hope that these experimental treatments, some of which have been tested in patients, will kill superbugs without promoting resistance.
"The vision, for me, is that we move beyond antibiotics and really just see a much broader palate of options," Chase Beisel, leader of the RNA synthetic biology research group at the Helmholtz Institute for RNA-based Infection Research in Germany, told Live Science.
But until these new therapeutics are ready for prime time, the world needs to curtail its overuse and misuse of antibiotics, which experts say is speeding up the rate at which these lifesaving drugs become obsolete.
|
37488
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
(Image credit: Centers for Disease Control and Prevention. Adapted by Live Science from the CDC's "Select Germs Showing Resistance Over Time" Fact Sheet.)
So some scientists are looking beyond traditional antibiotics for new weapons that won't fuel the rise of superbugs. Their emerging arsenal features viruses that kill bacteria; CRISPR; and microbe-slaying molecules. They hope that these experimental treatments, some of which have been tested in patients, will kill superbugs without promoting resistance.
"The vision, for me, is that we move beyond antibiotics and really just see a much broader palate of options," Chase Beisel, leader of the RNA synthetic biology research group at the Helmholtz Institute for RNA-based Infection Research in Germany, told Live Science.
But until these new therapeutics are ready for prime time, the world needs to curtail its overuse and misuse of antibiotics, which experts say is speeding up the rate at which these lifesaving drugs become obsolete.
Related: Superbugs are on the rise.
|
37489
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
Adapted by Live Science from the CDC's "Select Germs Showing Resistance Over Time" Fact Sheet.)
So some scientists are looking beyond traditional antibiotics for new weapons that won't fuel the rise of superbugs. Their emerging arsenal features viruses that kill bacteria; CRISPR; and microbe-slaying molecules. They hope that these experimental treatments, some of which have been tested in patients, will kill superbugs without promoting resistance.
"The vision, for me, is that we move beyond antibiotics and really just see a much broader palate of options," Chase Beisel, leader of the RNA synthetic biology research group at the Helmholtz Institute for RNA-based Infection Research in Germany, told Live Science.
But until these new therapeutics are ready for prime time, the world needs to curtail its overuse and misuse of antibiotics, which experts say is speeding up the rate at which these lifesaving drugs become obsolete.
Related: Superbugs are on the rise. How can we prevent antibiotics from becoming obsolete?
|
37490
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
So some scientists are looking beyond traditional antibiotics for new weapons that won't fuel the rise of superbugs. Their emerging arsenal features viruses that kill bacteria; CRISPR; and microbe-slaying molecules. They hope that these experimental treatments, some of which have been tested in patients, will kill superbugs without promoting resistance.
"The vision, for me, is that we move beyond antibiotics and really just see a much broader palate of options," Chase Beisel, leader of the RNA synthetic biology research group at the Helmholtz Institute for RNA-based Infection Research in Germany, told Live Science.
But until these new therapeutics are ready for prime time, the world needs to curtail its overuse and misuse of antibiotics, which experts say is speeding up the rate at which these lifesaving drugs become obsolete.
Related: Superbugs are on the rise. How can we prevent antibiotics from becoming obsolete?
How antibiotic resistance emerges and spreads
Antibiotics either directly kill bacteria or slow their growth , leaving the immune system to finish the job.
|
37491
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
Their emerging arsenal features viruses that kill bacteria; CRISPR; and microbe-slaying molecules. They hope that these experimental treatments, some of which have been tested in patients, will kill superbugs without promoting resistance.
"The vision, for me, is that we move beyond antibiotics and really just see a much broader palate of options," Chase Beisel, leader of the RNA synthetic biology research group at the Helmholtz Institute for RNA-based Infection Research in Germany, told Live Science.
But until these new therapeutics are ready for prime time, the world needs to curtail its overuse and misuse of antibiotics, which experts say is speeding up the rate at which these lifesaving drugs become obsolete.
Related: Superbugs are on the rise. How can we prevent antibiotics from becoming obsolete?
How antibiotic resistance emerges and spreads
Antibiotics either directly kill bacteria or slow their growth , leaving the immune system to finish the job. The drugs work in several ways — by preventing bacteria from building sturdy walls or making copies of their DNA , for instance.
|
37492
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
They hope that these experimental treatments, some of which have been tested in patients, will kill superbugs without promoting resistance.
"The vision, for me, is that we move beyond antibiotics and really just see a much broader palate of options," Chase Beisel, leader of the RNA synthetic biology research group at the Helmholtz Institute for RNA-based Infection Research in Germany, told Live Science.
But until these new therapeutics are ready for prime time, the world needs to curtail its overuse and misuse of antibiotics, which experts say is speeding up the rate at which these lifesaving drugs become obsolete.
Related: Superbugs are on the rise. How can we prevent antibiotics from becoming obsolete?
How antibiotic resistance emerges and spreads
Antibiotics either directly kill bacteria or slow their growth , leaving the immune system to finish the job. The drugs work in several ways — by preventing bacteria from building sturdy walls or making copies of their DNA , for instance. Growth-slowing antibiotics usually disrupt ribosomes, the factories in which bacterial cells make proteins.
|
37493
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
"The vision, for me, is that we move beyond antibiotics and really just see a much broader palate of options," Chase Beisel, leader of the RNA synthetic biology research group at the Helmholtz Institute for RNA-based Infection Research in Germany, told Live Science.
But until these new therapeutics are ready for prime time, the world needs to curtail its overuse and misuse of antibiotics, which experts say is speeding up the rate at which these lifesaving drugs become obsolete.
Related: Superbugs are on the rise. How can we prevent antibiotics from becoming obsolete?
How antibiotic resistance emerges and spreads
Antibiotics either directly kill bacteria or slow their growth , leaving the immune system to finish the job. The drugs work in several ways — by preventing bacteria from building sturdy walls or making copies of their DNA , for instance. Growth-slowing antibiotics usually disrupt ribosomes, the factories in which bacterial cells make proteins.
Many antibiotics shoot for the exact same molecular targets , and so-called broad-spectrum antibiotics' mechanisms are so universal that they work on both major classes of bacteria : gram-positive and gram-negative, which are distinguished by the makeup and thickness of their cell walls.
|
37494
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
But until these new therapeutics are ready for prime time, the world needs to curtail its overuse and misuse of antibiotics, which experts say is speeding up the rate at which these lifesaving drugs become obsolete.
Related: Superbugs are on the rise. How can we prevent antibiotics from becoming obsolete?
How antibiotic resistance emerges and spreads
Antibiotics either directly kill bacteria or slow their growth , leaving the immune system to finish the job. The drugs work in several ways — by preventing bacteria from building sturdy walls or making copies of their DNA , for instance. Growth-slowing antibiotics usually disrupt ribosomes, the factories in which bacterial cells make proteins.
Many antibiotics shoot for the exact same molecular targets , and so-called broad-spectrum antibiotics' mechanisms are so universal that they work on both major classes of bacteria : gram-positive and gram-negative, which are distinguished by the makeup and thickness of their cell walls. Broad-spectrum antibiotics, in particular, pressure both harmful and helpful bacteria in the body to evolve defensive strategies that eject or disable the drugs, or else alter their targets.
|
37495
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
Related: Superbugs are on the rise. How can we prevent antibiotics from becoming obsolete?
How antibiotic resistance emerges and spreads
Antibiotics either directly kill bacteria or slow their growth , leaving the immune system to finish the job. The drugs work in several ways — by preventing bacteria from building sturdy walls or making copies of their DNA , for instance. Growth-slowing antibiotics usually disrupt ribosomes, the factories in which bacterial cells make proteins.
Many antibiotics shoot for the exact same molecular targets , and so-called broad-spectrum antibiotics' mechanisms are so universal that they work on both major classes of bacteria : gram-positive and gram-negative, which are distinguished by the makeup and thickness of their cell walls. Broad-spectrum antibiotics, in particular, pressure both harmful and helpful bacteria in the body to evolve defensive strategies that eject or disable the drugs, or else alter their targets.
Drug-resistant bacteria can transfer their resistance to additional bacteria in several ways.
|
37496
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
Related: Superbugs are on the rise. How can we prevent antibiotics from becoming obsolete?
How antibiotic resistance emerges and spreads
Antibiotics either directly kill bacteria or slow their growth , leaving the immune system to finish the job. The drugs work in several ways — by preventing bacteria from building sturdy walls or making copies of their DNA , for instance. Growth-slowing antibiotics usually disrupt ribosomes, the factories in which bacterial cells make proteins.
Many antibiotics shoot for the exact same molecular targets , and so-called broad-spectrum antibiotics' mechanisms are so universal that they work on both major classes of bacteria : gram-positive and gram-negative, which are distinguished by the makeup and thickness of their cell walls. Broad-spectrum antibiotics, in particular, pressure both harmful and helpful bacteria in the body to evolve defensive strategies that eject or disable the drugs, or else alter their targets.
Drug-resistant bacteria can transfer their resistance to additional bacteria in several ways. (Image credit: Centers for Disease Control and Prevention.
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37497
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Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
How can we prevent antibiotics from becoming obsolete?
How antibiotic resistance emerges and spreads
Antibiotics either directly kill bacteria or slow their growth , leaving the immune system to finish the job. The drugs work in several ways — by preventing bacteria from building sturdy walls or making copies of their DNA , for instance. Growth-slowing antibiotics usually disrupt ribosomes, the factories in which bacterial cells make proteins.
Many antibiotics shoot for the exact same molecular targets , and so-called broad-spectrum antibiotics' mechanisms are so universal that they work on both major classes of bacteria : gram-positive and gram-negative, which are distinguished by the makeup and thickness of their cell walls. Broad-spectrum antibiotics, in particular, pressure both harmful and helpful bacteria in the body to evolve defensive strategies that eject or disable the drugs, or else alter their targets.
Drug-resistant bacteria can transfer their resistance to additional bacteria in several ways. (Image credit: Centers for Disease Control and Prevention. Adapted by Live Science from the CDC's "How Resistance Moves Directly Germ to Germ" Fact Sheet.)
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37498
|
Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
The drugs work in several ways — by preventing bacteria from building sturdy walls or making copies of their DNA , for instance. Growth-slowing antibiotics usually disrupt ribosomes, the factories in which bacterial cells make proteins.
Many antibiotics shoot for the exact same molecular targets , and so-called broad-spectrum antibiotics' mechanisms are so universal that they work on both major classes of bacteria : gram-positive and gram-negative, which are distinguished by the makeup and thickness of their cell walls. Broad-spectrum antibiotics, in particular, pressure both harmful and helpful bacteria in the body to evolve defensive strategies that eject or disable the drugs, or else alter their targets.
Drug-resistant bacteria can transfer their resistance to additional bacteria in several ways. (Image credit: Centers for Disease Control and Prevention. Adapted by Live Science from the CDC's "How Resistance Moves Directly Germ to Germ" Fact Sheet.)
Bacteria can pick up such defenses through random DNA mutations, or by swapping "resistance genes" with other bacteria via a process called horizontal gene transfer.
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37499
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Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can?
Growth-slowing antibiotics usually disrupt ribosomes, the factories in which bacterial cells make proteins.
Many antibiotics shoot for the exact same molecular targets , and so-called broad-spectrum antibiotics' mechanisms are so universal that they work on both major classes of bacteria : gram-positive and gram-negative, which are distinguished by the makeup and thickness of their cell walls. Broad-spectrum antibiotics, in particular, pressure both harmful and helpful bacteria in the body to evolve defensive strategies that eject or disable the drugs, or else alter their targets.
Drug-resistant bacteria can transfer their resistance to additional bacteria in several ways. (Image credit: Centers for Disease Control and Prevention. Adapted by Live Science from the CDC's "How Resistance Moves Directly Germ to Germ" Fact Sheet.)
Bacteria can pick up such defenses through random DNA mutations, or by swapping "resistance genes" with other bacteria via a process called horizontal gene transfer. By making these gene transfers, bacteria can quickly spread such mutations to additional bacterial populations in the body and in the environment.
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