Split (1)

train · 40.5k rows

id stringlengths 1 5	contents stringlengths 354 1.98k
37500	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Many antibiotics shoot for the exact same molecular targets , and so-called broad-spectrum antibiotics' mechanisms are so universal that they work on both major classes of bacteria : gram-positive and gram-negative, which are d...
37501	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Broad-spectrum antibiotics, in particular, pressure both harmful and helpful bacteria in the body to evolve defensive strategies that eject or disable the drugs, or else alter their targets. Drug-resistant bacteria can transfe...
37502	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Broad-spectrum antibiotics, in particular, pressure both harmful and helpful bacteria in the body to evolve defensive strategies that eject or disable the drugs, or else alter their targets. Drug-resistant bacteria can transfe...
37503	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? (Image credit: Centers for Disease Control and Prevention. Adapted by Live Science from the CDC's "How Resistance Moves Directly Germ to Germ" Fact Sheet.) Bacteria can pick up such defenses through random DNA mutations, or by...
37504	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Bacteria can pick up such defenses through random DNA mutations, or by swapping "resistance genes" with other bacteria via a process called horizontal gene transfer. By making these gene transfers, bacteria can quickly spread s...
37505	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? By making these gene transfers, bacteria can quickly spread such mutations to additional bacterial populations in the body and in the environment. The misuse of antibiotics in health care, as well as in agriculture, has given ...
37506	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? The misuse of antibiotics in health care, as well as in agriculture, has given bacteria endless opportunities to develop resistance, raising the chance that once-treatable infections will become life-threatening. Related: New ...
37507	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Related: New 'concerning' strain of drug-resistant gonorrhea found in U.S. for 1st time Harnessing viruses to fight bacteria One of the proposed alternatives to antibiotics was first conceived more than a century ago, before ...
37508	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? for 1st time Harnessing viruses to fight bacteria One of the proposed alternatives to antibiotics was first conceived more than a century ago, before the 1928 discovery of penicillin. Called phage therapy, it uses bacteria-in...
37509	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Called phage therapy, it uses bacteria-infecting viruses called bacteriophages, or simply "phages," which typically kill the germs by invading their cells and splitting them open from the inside. Phages can also pressure bacte...
37510	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Phages can also pressure bacteria into giving up key tools in their drug resistance tool kits. For example, a phage called U136B can have this effect on E. coli. To infiltrate E. coli, the phage uses an efflux pump, a protein E...
37511	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? For example, a phage called U136B can have this effect on E. coli. To infiltrate E. coli, the phage uses an efflux pump, a protein E. coli normally uses to pump antibiotics out of the cell. If the E. coli tries to change this p...
37512	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? If the E. coli tries to change this pump to escape the phage, it reduces the bacterium's ability to pump out antibiotics. "If phage therapy were used at a global scale ... it would not lead to the same problem of widespread re...
37513	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? "If phage therapy were used at a global scale ... it would not lead to the same problem of widespread resistance." Paul Turner, Yale University And unlike with antibiotics, bacteria are unlikely to gain widespread resistance t...
37514	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Turner and other experts have concluded that, "if phage therapy were used at a global scale, that it would not lead to the same problem of widespread resistance to it, the way that antibiotic use has led to that problem," he to...
37515	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Turner and other experts have concluded that, "if phage therapy were used at a global scale, that it would not lead to the same problem of widespread resistance to it, the way that antibiotic use has led to that problem," he to...
37516	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Here's why: Antibiotic resistance has been dramatically accelerated by the misuse and overuse of antibiotics , especially broad-spectrum antibiotics that work on a variety of bacteria. Phages, by contrast, can have much narrowe...
37517	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Here's why: Antibiotic resistance has been dramatically accelerated by the misuse and overuse of antibiotics , especially broad-spectrum antibiotics that work on a variety of bacteria. Phages, by contrast, can have much narrowe...
37518	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Phages, by contrast, can have much narrower targets than even narrow-spectrum antibiotics — for instance, targeting a protein found in only one or a few strains within one bacterial species. Related: New drugs could stymie sup...
37519	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Related: New drugs could stymie superbugs by freezing evolution The target bacterium can still evolve resistance to an individual phage — but by picking the right combination of phages, scientists can make it so that the bacte...
37520	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Related: New drugs could stymie superbugs by freezing evolution The target bacterium can still evolve resistance to an individual phage — but by picking the right combination of phages, scientists can make it so that the bacte...
37521	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? This cost might be a decrease in virulence or an increased vulnerability to antibiotics. (Image credit: Graphic made by Olha Pohrebniak via Getty Images. Adapted by Live Science.) To date, phage therapy has mostly been tested...
37522	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? This cost might be a decrease in virulence or an increased vulnerability to antibiotics. (Image credit: Graphic made by Olha Pohrebniak via Getty Images. Adapted by Live Science.) To date, phage therapy has mostly been tested...
37523	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? (Image credit: Graphic made by Olha Pohrebniak via Getty Images. Adapted by Live Science.) To date, phage therapy has mostly been tested through a regulatory framework known as "compassionate use" in patients like the Brussels...
37524	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? To date, phage therapy has mostly been tested through a regulatory framework known as "compassionate use" in patients like the Brussels Airport bombing victim, whose infections had no other treatment options. Phage therapy has ...
37525	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Phage therapy has shown success in these settings, and in a recent observational study of 100 patients who received phages alongside antibiotics. So far in clinical trials, though, phage therapy generally hasn't worked better ...
37526	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Topline results from two recent trials hint at the treatment's effectiveness in specific lung and foot infections, but the full results have yet to be released. Success in future trials will be key to getting phages into the c...
37527	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Success in future trials will be key to getting phages into the clinic, Turner said. Those trials will have to show the therapy works for multiple types of infections, determine dosage and confirm phage therapies don't hurt hel...
37528	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Turning bacteria's defenses against them The CRISPR-Cas system can be used to snip DNA at precise locations. Here, a Cas enzyme (dark pink) is preparing to cut through a target DNA strand (blue) and is being told where to cut ...
37529	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Here, a Cas enzyme (dark pink) is preparing to cut through a target DNA strand (blue) and is being told where to cut by an RNA strand (yellow). (Image credit: Meletios Verras via Getty Images) Although made famous as a powerfu...
37530	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? (Image credit: Meletios Verras via Getty Images) Although made famous as a powerful gene-editing tool, CRISPR technology was actually adapted from an immune system found in many bacteria: CRISPR-Cas. The key components of thi...
37531	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? The key components of this immune system include molecular scissors, known as Cas proteins, and a memory bank of DNA snippets that a bacterium has collected from phages that once infected it. By tapping its memory bank, CRISPR-...
37532	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? By tapping its memory bank, CRISPR-Cas can guide its lethal scissors to a precise point in an invading phage's DNA and snip it like a piece of ribbon. "The CRISPR machinery gets into a set of cells, but only those that have th...
37533	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? "The CRISPR machinery gets into a set of cells, but only those that have the sequence or sequences you picked will be attacked and killed." Chase Beisel, HIRI On occasion, though, rather than attacking phages, CRISPR-Cas can a...
37534	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? "The CRISPR machinery gets into a set of cells, but only those that have the sequence or sequences you picked will be attacked and killed." Chase Beisel, HIRI On occasion, though, rather than attacking phages, CRISPR-Cas can a...
37535	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Chase Beisel, HIRI On occasion, though, rather than attacking phages, CRISPR-Cas can accidentally go after the bacterial cell's own DNA , triggering a lethal autoimmune reaction. This phenomenon inspired Beisel and his colleag...
37536	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? "The real draw of it is that it is a sequence-specific tool," meaning it targets only the DNA you tell it to, and not sequences present in other bacteria, Beisel told Live Science. So, once administered to a patient, "the CRISP...
37537	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? So, once administered to a patient, "the CRISPR machinery gets into a set of cells, but only those that have the sequence or sequences you picked will be attacked and killed." How do you get CRISPR-Cas into the right bacteria?...
37538	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? How do you get CRISPR-Cas into the right bacteria? Various research groups are testing different delivery methods, but at present, the best strategy seems to be loading CRISPR machinery into a phage that infects the target bact...
37539	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? How do you get CRISPR-Cas into the right bacteria? Various research groups are testing different delivery methods, but at present, the best strategy seems to be loading CRISPR machinery into a phage that infects the target bact...
37540	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Related: Scientists invent 'shape-shifting' antibiotic to fight deadly superbugs Beisel is a co-founder and scientific adviser of Locus Biosciences, a biotech company that's currently testing a CRISPR-enhanced phage therapy in...
37541	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? This approach couples the bacteria-killing prowess of phages with the ability of CRISPR-Cas to destroy essential bacterial genes. As with CRISPR-less phage therapies, clinical trials are needed to determine the treatment's safe...
37542	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? This approach couples the bacteria-killing prowess of phages with the ability of CRISPR-Cas to destroy essential bacterial genes. As with CRISPR-less phage therapies, clinical trials are needed to determine the treatment's safe...
37543	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? "I can see these [treatments] coming about in the five- to 10-year time frame," Beisel said. Designer molecules to kill bacteria Beyond phages and CRISPR, scientists are developing antibiotic alternatives that harness bacteri...
37544	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Designer molecules to kill bacteria Beyond phages and CRISPR, scientists are developing antibiotic alternatives that harness bacteria-slaying peptides — short chains of protein building blocks— and enzymes, specialized protein...
37545	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? These molecules differ from antibiotics because they can kill a very narrow range of bacteria by targeting bacterial proteins that cannot easily gain resistance to their attacks. Lab-made molecules called peptide nucleic acids...
37546	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? These molecules differ from antibiotics because they can kill a very narrow range of bacteria by targeting bacterial proteins that cannot easily gain resistance to their attacks. Lab-made molecules called peptide nucleic acids...
37547	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Lab-made molecules called peptide nucleic acids (PNAs) are some of the most promising candidates. These engineered molecules can be designed to block bacterial cells from building essential proteins that are crucial to their su...
37548	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? PNAs do this by latching onto specific mRNA, genetic molecules that carry the instructions for building proteins from the cell's control center to its protein construction sites. PNAs cannot enter bacterial cells on their own, ...
37549	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? PNAs cannot enter bacterial cells on their own, though, so they're typically attached to other peptides that easily pass through the bacterial cell wall. By targeting proteins that cells cannot change without harming themselve...
37550	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? By targeting proteins that cells cannot change without harming themselves, PNAs can avoid triggering drug resistance, Beisel explained. The engineered molecules could also be made to target proteins that directly contribute to ...
37551	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? The engineered molecules could also be made to target proteins that directly contribute to antibiotic resistance, for example, the efflux pumps used to push antibiotics out of cells or the enzymes capable of disabling the drugs...
37552	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? By emptying a germ's drug resistance tool kit, PNAs can then make it vulnerable to standard treatments. One approach for killing bacteria is to use lysins, or enzymes that tear open bacterial cell membranes and cause the micro...
37553	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? By emptying a germ's drug resistance tool kit, PNAs can then make it vulnerable to standard treatments. One approach for killing bacteria is to use lysins, or enzymes that tear open bacterial cell membranes and cause the micro...
37554	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? One approach for killing bacteria is to use lysins, or enzymes that tear open bacterial cell membranes and cause the microbes' contents to spill out. (Image credit: KATERYNA KON/SCIENCE PHOTO LIBRARY via Getty Images) Antibact...
37555	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? (Image credit: KATERYNA KON/SCIENCE PHOTO LIBRARY via Getty Images) Antibacterial PNAs are still being tested in lab dishes and animals and have not yet moved into human trials. And, scientists need to make sure PNA-based trea...
37556	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? And, scientists need to make sure PNA-based treatments don't inadvertently mess with human cells or helpful bacteria. Related: 'Death screams' of swarming bacteria help their comrades survive antibiotic attacks In addition to...
37557	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Related: 'Death screams' of swarming bacteria help their comrades survive antibiotic attacks In addition to peptides like PNAs, enzymes called lysins are another promising treatment option. Lysins are used in nature by phages ...
37558	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? They act like tiny swords that slice through the outer wall of a bacterial cell, spilling its guts. The molecular sabers are unlikely to promote resistance because bacteria cannot easily change the essential cell-wall component...
37559	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? The molecular sabers are unlikely to promote resistance because bacteria cannot easily change the essential cell-wall components that lysins target. Lysins slaughter bacteria quickly upon contact, and they can be very specific...
37560	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? The molecular sabers are unlikely to promote resistance because bacteria cannot easily change the essential cell-wall components that lysins target. Lysins slaughter bacteria quickly upon contact, and they can be very specific...
37561	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Furthermore, lysins can be tweaked in the lab to change which bacteria they target, boost their potency and improve their durability in the body. Some lysins have entered mid- and late-stage human trials with hundreds of parti...
37562	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Some lysins have entered mid- and late-stage human trials with hundreds of participants, in which they've been tested as supplementary treatments to antibiotics but garnered mixed results. Antibiotic stewardship can save lives...
37563	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? Antibiotic stewardship can save lives, in the meantime Until these next-gen bacteria slayers make it to market, immediate measures must be taken to stall the rise of superbugs, by preventing the misuse of antibiotics that pres...
37564	Dangerous 'superbugs' are a growing threat, and antibiotics can't stop their rise. What can? "By reducing individual risk, you anticipate that you will drop the overall population-level risk." Dr. Shruti Gohil, INSPIRE-ASP Trials For example, doctors can be more diligent about confirming that bacteria, not viruses, ar...
37565	The 26 best Amazon Prime Day deals you can still shop for today Engadget has been testing and reviewing consumer tech since 2004. Our stories may include affiliate links; if you buy something through a link, we may earn a commission. Read more about how we evaluate products. Amazon's October Prime Day sale officially ...
37566	The 26 best Amazon Prime Day deals you can still shop for today Engadget has been testing and reviewing consumer tech since 2004. Our stories may include affiliate links; if you buy something through a link, we may earn a commission. Read more about how we evaluate products. Amazon's October Prime Day sale officially ...
37567	The 26 best Amazon Prime Day deals you can still shop for today Read more about how we evaluate products. Amazon's October Prime Day sale officially ended on Wednesday, but a few of the deals are still live as we head into the weekend. If you were hoping to check off a few more names from your holiday gift list or buy...
37568	The 26 best Amazon Prime Day deals you can still shop for today Amazon's October Prime Day sale officially ended on Wednesday, but a few of the deals are still live as we head into the weekend. If you were hoping to check off a few more names from your holiday gift list or buy something for yourself at a discount, see ...
37569	The 26 best Amazon Prime Day deals you can still shop for today We combed through our coverage over the past few days to find the best of what's left. While Amazon has returned most of their own devices, like Echos and Kindles, back to their full prices, a handful of products from other brands like Google, Samsung and ...
37570	The 26 best Amazon Prime Day deals you can still shop for today While Amazon has returned most of their own devices, like Echos and Kindles, back to their full prices, a handful of products from other brands like Google, Samsung and Anker, have maintained the lows they hit on Prime Day. Here are the best deals from Pri...
37571	The 26 best Amazon Prime Day deals you can still shop for today Samsung Galaxy Watch 6 The new Samsung Galaxy Watch 6 went down to $269 for October Prime Day and it's still on sale. That's lowest price we've seen since it came out a few months ago. You can't get a better smartwatch than this one if you have an Android...
37572	The 26 best Amazon Prime Day deals you can still shop for today That's lowest price we've seen since it came out a few months ago. You can't get a better smartwatch than this one if you have an Android phone (bonus points if you have a Samsung phone), and it's smaller and lighter than previous versions. Samsung brought...
37573	The 26 best Amazon Prime Day deals you can still shop for today Samsung brought back the spinning bezel on the Classic version, which is which makes the software's UI easier to navigate, plus it has improved performance and updated health and fitness tracking tools. Apple MacBook Air M2 (15-inch) Photo by Nathan Ingr...
37574	The 26 best Amazon Prime Day deals you can still shop for today Samsung brought back the spinning bezel on the Classic version, which is which makes the software's UI easier to navigate, plus it has improved performance and updated health and fitness tracking tools. Apple MacBook Air M2 (15-inch) Photo by Nathan Ingr...
37575	The 26 best Amazon Prime Day deals you can still shop for today Other SKUs with more RAM and storage are also on sale. $1,049 at Amazon The 15.3-inch version of Apple’s MacBook Air is still down to $1,049 for an entry-level model with 8GB of RAM and a 256GB SSD. That matches the best price we’ve seen and takes $250 of...
37576	The 26 best Amazon Prime Day deals you can still shop for today Other SKUs with more RAM and storage are also on sale. $1,049 at Amazon The 15.3-inch version of Apple’s MacBook Air is still down to $1,049 for an entry-level model with 8GB of RAM and a 256GB SSD. That matches the best price we’ve seen and takes $250 of...
37577	The 26 best Amazon Prime Day deals you can still shop for today That matches the best price we’ve seen and takes $250 off Apple’s list price. The MacBook Air is the top pick in our guide to the best laptops, and we gave the 15-inch model a review score of 96 earlier this year, as it covers just about all of the things ...
37578	The 26 best Amazon Prime Day deals you can still shop for today The MacBook Air is the top pick in our guide to the best laptops, and we gave the 15-inch model a review score of 96 earlier this year, as it covers just about all of the things we look for in a quality mainstream notebook. Compared to the 13.6-inch versio...
37579	The 26 best Amazon Prime Day deals you can still shop for today Compared to the 13.6-inch version, it also includes a more powerful speaker system and a slightly upgraded GPU. The SSD in this base configuration is technically slower than the one in higher-capacity SKUs, but that shouldn’t be a major problem unless you’...
37580	The 26 best Amazon Prime Day deals you can still shop for today Compared to the 13.6-inch version, it also includes a more powerful speaker system and a slightly upgraded GPU. The SSD in this base configuration is technically slower than the one in higher-capacity SKUs, but that shouldn’t be a major problem unless you’...
37581	The 26 best Amazon Prime Day deals you can still shop for today The SSD in this base configuration is technically slower than the one in higher-capacity SKUs, but that shouldn’t be a major problem unless you’re looking to do more complex work. In general, you wouldn’t buy the Air for things like high-res media editing,...
37582	The 26 best Amazon Prime Day deals you can still shop for today In general, you wouldn’t buy the Air for things like high-res media editing, though its M2 chip is still plenty powerful for everyday tasks. If you do need more storage space, the 512GB model with 8GB of RAM is on sale for a low of $1,249. Variants with d...
37583	The 26 best Amazon Prime Day deals you can still shop for today If you do need more storage space, the 512GB model with 8GB of RAM is on sale for a low of $1,249. Variants with double the RAM are up to $250 off as well. Meanwhile, the 13.6-inch MacBook Air isn’t discounted on Amazon, but it’s down to $899 at Best Buy. ...
37584	The 26 best Amazon Prime Day deals you can still shop for today Variants with double the RAM are up to $250 off as well. Meanwhile, the 13.6-inch MacBook Air isn’t discounted on Amazon, but it’s down to $899 at Best Buy. That’s $200 off the notebook’s list price. Sony WF-1000XM5 Sony's WF-1000XM5 wireless earbuds wen...
37585	The 26 best Amazon Prime Day deals you can still shop for today That’s $200 off the notebook’s list price. Sony WF-1000XM5 Sony's WF-1000XM5 wireless earbuds went down to $278 for Prime Day and are still going for that price today. That's a $22 discount and their best price yet. We think these are the best wireless e...
37586	The 26 best Amazon Prime Day deals you can still shop for today Sony WF-1000XM5 Sony's WF-1000XM5 wireless earbuds went down to $278 for Prime Day and are still going for that price today. That's a $22 discount and their best price yet. We think these are the best wireless earbuds on the market right now. Sony improve...
37587	The 26 best Amazon Prime Day deals you can still shop for today That's a $22 discount and their best price yet. We think these are the best wireless earbuds on the market right now. Sony improved upon it's already remarkable buds with a more comfortable fit, better sound quality and features likes adaptive sound and Sp...
37588	The 26 best Amazon Prime Day deals you can still shop for today We think these are the best wireless earbuds on the market right now. Sony improved upon it's already remarkable buds with a more comfortable fit, better sound quality and features likes adaptive sound and Speak-to-Chat. Amazon Fire TV Stick 4K The previ...
37589	The 26 best Amazon Prime Day deals you can still shop for today Amazon Fire TV Stick 4K The previous generation of Fire TV Stick 4K dropped to $23 for the sale and is one of the few Amazon devices still on sale. It has the same processor, RAM and storage as the standard Fire TV Stick, but it can stream 4K HDR content ...
37590	The 26 best Amazon Prime Day deals you can still shop for today It has the same processor, RAM and storage as the standard Fire TV Stick, but it can stream 4K HDR content in all its glory. It also supports Dolby Vision HDR and Dolby Atmos, while a picture-in-picture live view feature can show you feeds from compatible ...
37591	The 26 best Amazon Prime Day deals you can still shop for today It has the same processor, RAM and storage as the standard Fire TV Stick, but it can stream 4K HDR content in all its glory. It also supports Dolby Vision HDR and Dolby Atmos, while a picture-in-picture live view feature can show you feeds from compatible ...
37592	The 26 best Amazon Prime Day deals you can still shop for today It also supports Dolby Vision HDR and Dolby Atmos, while a picture-in-picture live view feature can show you feeds from compatible security cameras right on your TV screen. Do note, though, that this is the previous model of the streaming stick. The newly...
37593	The 26 best Amazon Prime Day deals you can still shop for today Do note, though, that this is the previous model of the streaming stick. The newly refreshed Fire TV Stick 4K isn't sale but has a faster processor and supports Wi-Fi 6. Anker Soundcore Motion + One of the top Bluetooth options in our speaker guide is An...
37594	The 26 best Amazon Prime Day deals you can still shop for today Anker Soundcore Motion + One of the top Bluetooth options in our speaker guide is Anker’s Soundcore Motion +, which gives out good sound for its price point. The $100 MSRP is discounted to $70 if you clip the on-page copuon. That's a 30 percent discount a...
37595	The 26 best Amazon Prime Day deals you can still shop for today The $100 MSRP is discounted to $70 if you clip the on-page copuon. That's a 30 percent discount and an all-time low. It has a bright and bassy output and offers EQ customization in the app. Plus it’s water-resistant, so you can take it to the park or on a ...
37596	The 26 best Amazon Prime Day deals you can still shop for today That's a 30 percent discount and an all-time low. It has a bright and bassy output and offers EQ customization in the app. Plus it’s water-resistant, so you can take it to the park or on a hike and share your good taste in music with whoever is nearby. Hy...
37597	The 26 best Amazon Prime Day deals you can still shop for today HyperX Cloud Stinger 2 The top budget pick in our gaming headphones buying guide, the HyperX Cloud Stinger 2, is on sale for $36. That’s a dollar more than it went for on Prime Day and only a modest $4 discount over its street price recently, but it's sti...
37598	The 26 best Amazon Prime Day deals you can still shop for today That’s a dollar more than it went for on Prime Day and only a modest $4 discount over its street price recently, but it's still close to lowest price we’ve seen. The Cloud Stinger 2 doesn’t have the most balanced or detailed sound, but its V-shaped signatu...
37599	The 26 best Amazon Prime Day deals you can still shop for today That’s a dollar more than it went for on Prime Day and only a modest $4 discount over its street price recently, but it's still close to lowest price we’ve seen. The Cloud Stinger 2 doesn’t have the most balanced or detailed sound, but its V-shaped signatu...

Subsets and Splits

No community queries yet

The top public SQL queries from the community will appear here once available.