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Testis-determining factor
Testis-determining factor Testis-determining factor (TDF), also known as sex-determining region Y (SRY) protein, is a DNA-binding protein (also known as gene-regulatory protein/transcription factor) encoded by the SRY gene that is responsible for the initiation of male sex determination in humans. SRY is an intronless ...
Testis-determining factor Testis-determining factor (TDF), also known as sex-determining region Y (SRY) protein, is a DNA-binding protein (also known as gene-regulatory protein/transcription factor) encoded by the SRY gene that is responsible for the initiation of male sex determination in humans.[1] SRY is an intronl...
https://www.wikidoc.org/index.php/Testis-determining_factor
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wikidoc
Testis determining factor
Testis determining factor Testis-determining factor (TDF) is a general term for the gene (or product thereof) that results in maleness in humans and some other species. Certain genes cause chemical reactions that result in the development of testes. Embryos are gonadally identical, regardless of genetic sex, until a ce...
Testis determining factor Testis-determining factor (TDF) is a general term for the gene (or product thereof) that results in maleness in humans and some other species. Certain genes cause chemical reactions that result in the development of testes. Embryos are gonadally identical, regardless of genetic sex, until a c...
https://www.wikidoc.org/index.php/Testis_determining_factor
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wikidoc
The heart in lung cancers
The heart in lung cancers # Histopathological Findings Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology - Heart metastases from bronchogenic carcinoma - Heart metastases from bronchogenic carcinoma (closer look) - HEAR...
The heart in lung cancers Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2] # Histopathological Findings Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology - Hea...
https://www.wikidoc.org/index.php/The_Heart_in_Lung_Cancers
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The patient has back pain
The patient has back pain # ACTION ITEMS* 1. Obatin a history to fully characterize the nature back pain (onset, sti lml'f;,'fa;k;'ask. 2. Obtain a relevant ROS focusing on systemic diseases, cancer, infection, neurologic symptoms and character of the back pain. 2. Perform a focused physical examination - sign of loca...
The patient has back pain # ACTION ITEMS* 1. Obatin a history to fully characterize the nature back pain (onset, sti lml'f;,'fa;k;'ask. 2. Obtain a relevant ROS focusing on systemic diseases, cancer, infection, neurologic symptoms and character of the back pain. 2. Perform a focused physical examination - sign of loca...
https://www.wikidoc.org/index.php/The_patient_has_back_pain
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Theodor Wilhelm Engelmann
Theodor Wilhelm Engelmann Theodor Wilhelm Engelmann (born 1843 in Leipzig – died 1909) was a German botanist, physiologist, microbiologist, university professor, and musician whose 1882 experiment measured the effects of different colors of light on photosynthetic activity and showed that the conversion of light energy...
Theodor Wilhelm Engelmann Template:Infobox Scientist Theodor Wilhelm Engelmann (born 1843 in Leipzig – died 1909) was a German botanist, physiologist, microbiologist, university professor, and musician whose 1882 experiment measured the effects of different colors of light on photosynthetic activity and showed that th...
https://www.wikidoc.org/index.php/Theodor_Wilhelm_Engelmann
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Thermodynamic equilibrium
Thermodynamic equilibrium In thermodynamics, a thermodynamic system is said to be in thermodynamic equilibrium when it is in thermal equilibrium, mechanical equilibrium, and chemical equilibrium. The local state of a system at thermodynamic equilibrium is determined by the values of its intensive parameters, as pressur...
Thermodynamic equilibrium Template:Chemical equilibria In thermodynamics, a thermodynamic system is said to be in thermodynamic equilibrium when it is in thermal equilibrium, mechanical equilibrium, and chemical equilibrium. The local state of a system at thermodynamic equilibrium is determined by the values of its in...
https://www.wikidoc.org/index.php/Thermal_equilibrium
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Thin layer chromatography
Thin layer chromatography Thin layer chromatography (TLC) is a chromatography technique used to separate chemical compounds. It involves a stationary phase consisting of a thin layer of adsorbent material, usually silica gel, aluminium oxide, or cellulose immobilized onto a flat, inert carrier sheet. A liquid phase con...
Thin layer chromatography Template:Infobox chemical analysis Thin layer chromatography (TLC) is a chromatography technique used to separate chemical compounds.[1] It involves a stationary phase consisting of a thin layer of adsorbent material, usually silica gel, aluminium oxide, or cellulose immobilized onto a flat, ...
https://www.wikidoc.org/index.php/Thin_layer_chromatography
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Thrombocytopenia
Thrombocytopenia overview # Overview Thrombocytopenia (or -paenia, or thrombopenia in short) is the presence of relatively few platelets in blood. Generally speaking, a normal platelet count ranges from 150,000 and 450,000 per mm3. These limits, however, are determined by the 2.5th lower and upper percentile, and a de...
Thrombocytopenia overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor-In-Chief: Farbod Zahedi Tajrishi, M.D. [2] # Overview Thrombocytopenia (or -paenia, or thrombopenia in short) is the presence of relatively few platelets in blood. Generally speaking, a normal platelet count ranges from 150...
https://www.wikidoc.org/index.php/Thrombocytopenia_overview
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Thymic carcinoma
Thymic carcinoma overview # Overview Thymic carcinoma, also known as type C thymoma, is a rare condition (less than 0.13/100,000/year) but should be included in the differential diagnosis of anterior mediastinic masses. It is a tumor of the thymic epithelium, like thymoma, but it is associated with lack of immature l...
Thymic carcinoma overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Marjan Khan M.B.B.S.[2] # Overview Thymic carcinoma, also known as type C thymoma, is a rare condition (less than 0.13/100,000/year) but should be included in the differential diagnosis of anterior mediastini...
https://www.wikidoc.org/index.php/Thymic_carcinoma_overview
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Toxic leukoencephalopathy
Toxic leukoencephalopathy Toxic leukoencephalopathy or toxic spongiform leukoencephalopathy is a condition that is characterized by progressive damage (-pathy), of the white matter (leuko-) of the brain (-encephalo-) due to ingested toxins (toxic). It is seen in some people who ingest heroin by route of smoking (chasi...
Toxic leukoencephalopathy Template:Search infobox Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Toxic leukoencephalopathy or toxic spongiform leukoencephalopathy is a condition that is characterized by progressive damage (-pathy), of the white matter (leuko-) of the brain (-encephalo-) due to ingested toxins (to...
https://www.wikidoc.org/index.php/Toxic_leukoencephalopathy
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wikidoc
Toxic multinodular goitre
Toxic multinodular goitre # Overview Toxic multinodular goitre (also known as toxic nodular goitre, toxic nodular struma) is a form of hyperthyroidism - where there is excess production of thyroid hormones. It is the second most common cause of hyperthyroidism after Graves disease. # Symptoms Symptoms of toxic multin...
Toxic multinodular goitre Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-632-7753 # Overview Toxic multinodular goitre (also known as toxic nodular goitre, toxic nodular struma) is a form of hyperthyroidism - where there is excess production of thyroid hormones. It is the second most common cause of hyp...
https://www.wikidoc.org/index.php/Toxic_multinodular_goitre
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Trampoline Platysmaplasty
Trampoline Platysmaplasty # Overview The Trampoline Platysmaplasty, also sometimes called neck rejuvenation, lower facelift, lower rhytidectomy or necklift, is a specific cosmetic surgery technique to elevate neck muscles and glands to give a more youthful jawline. It usually involves the removal of excess fatty tissu...
Trampoline Platysmaplasty Editors-In-Chief: Martin I. Newman, M.D., FACS, Cleveland Clinic Florida, [1]; Michel C. Samson, M.D., FRCSC, FACS [2] # Overview The Trampoline Platysmaplasty, also sometimes called neck rejuvenation, lower facelift, lower rhytidectomy or necklift, is a specific cosmetic surgery technique ...
https://www.wikidoc.org/index.php/Trampoline_Platysmaplasty
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Transcription coregulator
Transcription coregulator In the field of molecular biology, transcription coregulators are proteins that interact with transcription factors to either activate or repress the transcription of specific genes. Transcription coregulators that activate gene transcription are referred to as coactivators while those that ...
Transcription coregulator Template:Transcription factor glossary In the field of molecular biology, transcription coregulators are proteins that interact with transcription factors to either activate or repress the transcription of specific genes.[1] Transcription coregulators that activate gene transcription are ref...
https://www.wikidoc.org/index.php/Transcription_coregulator
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Transcription factor II A
Transcription factor II A Transcription factor TFIIA is a nuclear protein involved in the RNA polymerase II-dependent transcription of DNA. TFIIA is one of several general (basal) transcription factors (GTFs) that are required for all transcription events that use RNA polymerase II. Other GTFs include TFIID, a comple...
Transcription factor II A Transcription factor TFIIA is a nuclear protein involved in the RNA polymerase II-dependent transcription of DNA.[1] TFIIA is one of several general (basal) transcription factors (GTFs) that are required for all transcription events that use RNA polymerase II. Other GTFs include TFIID, a co...
https://www.wikidoc.org/index.php/Transcription_factor_II_A
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Transcription factor II B
Transcription factor II B Transcription factor II B (TFIIB) is a general transcription factor that is involved in the formation of the RNA polymerase II preinitiation complex (PIC) and aids in stimulating transcription initiation. TFIIB is localised to the nucleus and provides a platform for PIC formation by binding an...
Transcription factor II B Transcription factor II B (TFIIB) is a general transcription factor that is involved in the formation of the RNA polymerase II preinitiation complex (PIC)[1] and aids in stimulating transcription initiation. TFIIB is localised to the nucleus and provides a platform for PIC formation by bindin...
https://www.wikidoc.org/index.php/Transcription_factor_II_B
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Transcription factor II F
Transcription factor II F Transcription factor IIF (TFIIF) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex. Transcription factor IIF is encoded by the GTF2F1, GTF2F2, and GTF2F2L genes. TFIIF binds to RNA Polymerase II when the enzyme is already unbound to any ot...
Transcription factor II F Transcription factor IIF (TFIIF) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex.[1][2][3] Transcription factor IIF is encoded by the GTF2F1, GTF2F2, and GTF2F2L genes.[4][5][6] TFIIF binds to RNA Polymerase II when the enzyme is alread...
https://www.wikidoc.org/index.php/Transcription_factor_II_F
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wikidoc
Transcription factor II H
Transcription factor II H Transcription factor II Human (Transcription Factor II H; TFIIH) is an important protein complex, having roles in transcription of various protein-coding genes and DNA nucleotide excision repair (NER) pathways. TFIIH first came to light in 1989 when general transcription factor-δ or basic tran...
Transcription factor II H Transcription factor II Human (Transcription Factor II H; TFIIH) is an important protein complex, having roles in transcription of various protein-coding genes and DNA nucleotide excision repair (NER) pathways. TFIIH first came to light in 1989 when general transcription factor-δ or basic tra...
https://www.wikidoc.org/index.php/Transcription_factor_II_H
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wikidoc
Transcription start sites
Transcription start sites The transcription start site is the location where transcription starts at the 5'-end of a gene sequence. Each human gene is made up of deoxyribonucleic acid (DNA) in a double helix. Along each helix which is composed of a phosphate-deoxyribose polymer are nitrogenous bases. These bases are li...
Transcription start sites Editor-In-Chief: Henry A. Hoff Template:TOCright The transcription start site is the location where transcription starts at the 5'-end of a gene sequence.[1] Each human gene is made up of deoxyribonucleic acid (DNA) in a double helix. Along each helix which is composed of a phosphate-deoxyrib...
https://www.wikidoc.org/index.php/Transcription_start_sites
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Transduction (biophysics)
Transduction (biophysics) In biophysics, transduction is the conveyance of energy from one electron (a donor) to another (a receptor), at the same time that the class of energy changes. Photonic energy, the kinetic energy of a photon, when interacting with an electron, may follow these paths: - stimulated emission as a...
Transduction (biophysics) Editor-In-Chief: Henry A. Hoff In biophysics, transduction is the conveyance of energy from one electron (a donor) to another (a receptor), at the same time that the class of energy changes. Photonic energy, the kinetic energy of a photon, when interacting with an electron, may follow these p...
https://www.wikidoc.org/index.php/Transduction_(biophysics)
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Transformation (genetics)
Transformation (genetics) In molecular biology, transformation is the genetic alteration of a cell resulting from the uptake, genomic incorporation, and expression of foreign genetic material (DNA). Separate terms are used for genetic alterations resulting from introduction of DNA by viruses ("transduction") or by cell...
Transformation (genetics) Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] In molecular biology, transformation is the genetic alteration of a cell resulting from the uptake, genomic incorporation, and expression of foreign genetic material (DNA). Separate terms are used for genetic alterations resulting from introd...
https://www.wikidoc.org/index.php/Transformation
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Transmembrane Protein 175
Transmembrane Protein 175 Transmembrane Protein 175, or TMEM175, is a transmembrane protein that is thought to be an endolysosomal potassium channel. It is predicted to have many orthologs across eukaryotes. # Expression Based on human and mouse EST profiles and a human tissue GEO profile, TMEM175 appears to be expres...
Transmembrane Protein 175 Transmembrane Protein 175, or TMEM175, is a transmembrane protein that is thought to be an endolysosomal potassium channel. It is predicted to have many orthologs across eukaryotes. # Expression Based on human and mouse EST profiles and a human tissue GEO profile, TMEM175 appears to be expre...
https://www.wikidoc.org/index.php/Transmembrane_Protein_175
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Transmembrane Protein 205
Transmembrane Protein 205 Transmembrane Protein 205 (TMEM205) is a protein encoded on chromosome 19 by the TMEM205 gene. # Gene TMEM205 is located on the minus strand of chromosome 19 from base pair 11,453,452 to 11,456,981. In close proximity to TMEM205, CCDC159 is located slightly upstream and RAB3D slightly down st...
Transmembrane Protein 205 Transmembrane Protein 205 (TMEM205) is a protein encoded on chromosome 19 by the TMEM205 gene. # Gene TMEM205 is located on the minus strand of chromosome 19 from base pair 11,453,452 to 11,456,981. In close proximity to TMEM205, CCDC159 is located slightly upstream and RAB3D slightly down s...
https://www.wikidoc.org/index.php/Transmembrane_Protein_205
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Transmembrane protein 134
Transmembrane protein 134 Transmembrane protein 134 is a protein encoded by the TMEM134 gene. TMEM134 does not have any other known aliases. There are two transmembrane domains and a domain of unknown function (DUF872). Evolutionary, the majority of the organisms that have this gene are primates and mammals, although...
Transmembrane protein 134 Transmembrane protein 134 is a protein encoded by the TMEM134 gene. TMEM134 does not have any other known aliases. There are two transmembrane domains and a domain of unknown function (DUF872).[1] Evolutionary, the majority of the organisms that have this gene are primates and mammals, alth...
https://www.wikidoc.org/index.php/Transmembrane_protein_134
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Transmembrane protein 222
Transmembrane protein 222 Transmembrane protein 222 is a protein that in humans is encoded by the TMEM222 gene. One notable feature of the protein encoded by this gene is the presence of three predicted transmembrane domains. The TMEM222 protein is predicted to most likely localize to the secretory vesicles. # Gene Fe...
Transmembrane protein 222 Transmembrane protein 222 is a protein that in humans is encoded by the TMEM222 gene.[1][2] One notable feature of the protein encoded by this gene is the presence of three predicted transmembrane domains.[3] The TMEM222 protein is predicted to most likely localize to the secretory vesicles.[...
https://www.wikidoc.org/index.php/Transmembrane_protein_222
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Transmembrane protein 254
Transmembrane protein 254 Transmembrane protein 254 is a transmembrane protein that is encoded by the TMEM254 gene, it is predicted to have many orthologs across eukaryotes. # Gene TMEM254 is located on the long arm of chromosome 10, open reading frame 57 on the positive strand. It is found at position 10q22.3. It has...
Transmembrane protein 254 Transmembrane protein 254 is a transmembrane protein that is encoded by the TMEM254 gene, it is predicted to have many orthologs across eukaryotes. # Gene TMEM254 is located on the long arm of chromosome 10, open reading frame 57 on the positive strand. It is found at position 10q22.3. It ha...
https://www.wikidoc.org/index.php/Transmembrane_protein_254
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wikidoc
Transmembrane protein 268
Transmembrane protein 268 Transmembrane protein 268 is a protein that in humans is encoded by TMEM268 gene. The protein is a transmembrane protein of 342 amino acids long with eight alternative splice variants. The protein has been identified in organisms from the common fruit fly to primates. To date, there has been n...
Transmembrane protein 268 Transmembrane protein 268 is a protein that in humans is encoded by TMEM268 gene. The protein is a transmembrane protein of 342 amino acids long with eight alternative splice variants. The protein has been identified in organisms from the common fruit fly to primates. To date, there has been ...
https://www.wikidoc.org/index.php/Transmembrane_protein_268
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Transthyretin amyloidosis
Transthyretin amyloidosis Synonyms and keywords: # Overview # Historical Perspective - In 1639, Nicolaus Fontanus autopsied a young man who had ascites, jaundice, liver abscess, and splenomegaly and his report has been the first description of amyloidosis. - In 1854, Rudolph Virchow introduced the term "amyloid" as a...
Transthyretin amyloidosis Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D. Synonyms and keywords: # Overview # Historical Perspective - In 1639, Nicolaus Fontanus autopsied a young man who had ascites, jaundice, liver abscess, and splenomegaly and his report ha...
https://www.wikidoc.org/index.php/Transthyretin_amyloidosis
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Treatment Based Questions
Treatment Based Questions # Treatment Based Questions ### Should dexamethasone be used to treat COVID-19 patients? - Preliminary evidence from a UK-based randomized clinical trial (The recovery trial) suggests dexamethasone reduced mortality for patients on ventilators by about 33% and by 20% in patients requiring ox...
Treatment Based Questions Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]: Associate Editor(s)-in-Chief: Aisha Adigun, B.Sc., M.D.[2]Nuha Al-Howthi, MD[3]Gurmandeep Singh Sandhu,M.B.B.S.[4] # Treatment Based Questions ### Should dexamethasone be used to treat COVID-19 patients? - Preliminary evidence from a UK-...
https://www.wikidoc.org/index.php/Treatment_Based_Questions
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Triamcinolone (injection)
Triamcinolone (injection) # Disclaimer WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational conten...
Triamcinolone (injection) Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Deepika Beereddy, MBBS [2] # Disclaimer WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc...
https://www.wikidoc.org/index.php/Triamcinolone_(injection)
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Tricaine methanesulfonate
Tricaine methanesulfonate Tricaine methanesulfonate (TMS), also called as MS-222, is white powder used for anesthesia or sedation of fishes (mainly salmonids). TMS is the only anesthetic licensed in the United States for fin fish that is intended for human consumption. TMS is a muscle relaxant that operates by preventi...
Tricaine methanesulfonate Template:Chembox new Tricaine methanesulfonate (TMS), also called as MS-222, is white powder used for anesthesia or sedation of fishes (mainly salmonids). TMS is the only anesthetic licensed in the United States for fin fish that is intended for human consumption. TMS is a muscle relaxant tha...
https://www.wikidoc.org/index.php/Tricaine_methanesulfonate
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Trichocereus scopulicolus
Trichocereus scopulicolus Trichocereus scopulicolus is a type of cactus native to Bolivia, which contains psychedelic compounds. Many claim this species contains mescaline, but there has never been any official studies done, so any speculation about its properties are without solid scientific support. # Names This ca...
Trichocereus scopulicolus Trichocereus scopulicolus is a type of cactus native to Bolivia, which contains psychedelic compounds. Many claim this species contains mescaline, but there has never been any official studies done, so any speculation about its properties are without solid scientific support. # Names This c...
https://www.wikidoc.org/index.php/Trichocereus_scopulicolus
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Trimethoprim microbiology
Trimethoprim microbiology # Microbiology Trimethoprim blocks the production of tetrahydrofolic acid from dihydrofolic acid by binding to and reversibly inhibiting the required enzyme, dihydrofolate reductase. This binding is very much stronger for the bacterial enzyme than for the corresponding mammalian enzyme. Thus,...
Trimethoprim microbiology Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2] # Microbiology Trimethoprim blocks the production of tetrahydrofolic acid from dihydrofolic acid by binding to and reversibly inhibiting the required enzyme, dihydrofolate reductase. This b...
https://www.wikidoc.org/index.php/Trimethoprim_microbiology
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Triosephosphate isomerase
Triosephosphate isomerase # Overview Triose-phosphate isomerase (TPI or TIM), is an enzyme (EC 5.3.1.1) that catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate. Compound C00111 at KEGG Pathway Database.Enzyme 5.3.1.1 at KEGG Pathway Data...
Triosephosphate isomerase Template:Protbox Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Triose-phosphate isomerase (TPI or TIM), is an enzyme (EC 5.3.1.1) that catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate. Compoun...
https://www.wikidoc.org/index.php/Triose-phosphate_isomerase
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Tubuloglomerular feedback
Tubuloglomerular feedback In the physiology of the kidney, tubuloglomerular feedback (TGF) is one of several mechanisms the kidney uses to regulate glomerular filtration rate (GFR). Changes in GFR are detected by the renal tubule, which sends feedback signals to the glomerulus, initiating a cascade of events that ultim...
Tubuloglomerular feedback In the physiology of the kidney, tubuloglomerular feedback (TGF) is one of several mechanisms the kidney uses to regulate glomerular filtration rate (GFR). Changes in GFR are detected by the renal tubule, which sends feedback signals to the glomerulus, initiating a cascade of events that ulti...
https://www.wikidoc.org/index.php/Tubuloglomerular_feedback
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Tyrosine aminotransferase
Tyrosine aminotransferase Tyrosine aminotransferase (or tyrosine transaminase) is an enzyme present in the liver and catalyzes the conversion of tyrosine to 4-hydroxyphenylpyruvate. In humans, the tyrosine aminotransferase protein is encoded by the TAT gene. A deficiency of the enzyme in humans can result in what is k...
Tyrosine aminotransferase Tyrosine aminotransferase (or tyrosine transaminase) is an enzyme present in the liver and catalyzes the conversion of tyrosine to 4-hydroxyphenylpyruvate.[2] In humans, the tyrosine aminotransferase protein is encoded by the TAT gene. A deficiency of the enzyme in humans can result in what ...
https://www.wikidoc.org/index.php/Tyrosine_aminotransferase
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USMLE step 1 biochemistry
USMLE step 1 biochemistry Ribosomes are made of proteins and rRNA - Eukaryotes → 60 and 40s = 80s - Prokaryotes → 50 s and 30 s = 70 s Have 23s in 50s - Have 23s in 50s Translation - Initiation IF1, IF2, If3 Assist in assembly of smaller ribosomal subunit to first trna molecule Methionine is always the start f-Methioni...
USMLE step 1 biochemistry Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Mahshid Mir, M.D. [2] Ribosomes are made of proteins and rRNA - Eukaryotes → 60 and 40s = 80s - Prokaryotes → 50 s and 30 s = 70 s Have 23s in 50s - Have 23s in 50s Translation - Initiation IF1, IF2, If3 Assist in assembly of smaller ribosoma...
https://www.wikidoc.org/index.php/USMLE_step_1_biochemistry
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wikidoc
U box gene transcriptions
U box gene transcriptions "The U box is a domain of ∼70 amino acids that is present in proteins from yeast to humans." "The prototype U box protein, yeast Ufd2, was identified as a ubiquitin chain assembly factor that cooperates with a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), and a ubiquit...
U box gene transcriptions Associate Editor(s)-in-Chief: Henry A. Hoff "The U box is a domain of ∼70 amino acids that is present in proteins from yeast to humans."[1] "The prototype U box protein, yeast Ufd2, was identified as a ubiquitin chain assembly factor that cooperates with a ubiquitin-activating enzyme (E1), a...
https://www.wikidoc.org/index.php/U_box_gene_transcriptions
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Umbilical hernia
Umbilical hernia overview # Overview Umbilical hernia is a congenital malformation, especially common in infants of African descent. However, it can be an acquired condition as well. In 1855, Dr. Henry Porter was the first to publish a case of umbilical hernia with rupture. In 1876, Dr. MG Oxley published a case of um...
Umbilical hernia overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hamid Qazi, MD, BSc [2] # Overview Umbilical hernia is a congenital malformation, especially common in infants of African descent. However, it can be an acquired condition as well. In 1855, Dr. Henry Porter wa...
https://www.wikidoc.org/index.php/Umbilical_hernia_overview
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Umbilical venous catheter
Umbilical venous catheter # Overview Umbilical venous catheters are commonly used in the neonatal period for vascular access. An umbilical venous catheter passes through the umbilicus, umbilical vein, left portal vein, ductus venosus, middle or left hepatic vein, and inferior vena cava to the junction of the inferior ...
Umbilical venous catheter Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Umbilical venous catheters are commonly used in the neonatal period for vascular access. An umbilical venous catheter passes through the umbilicus, umbilical vein, left portal vein, ductus venosus, middle or left hepatic vein, and...
https://www.wikidoc.org/index.php/Umbilical_venous_catheter
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Unfolded protein response
Unfolded protein response # Overview The unfolded protein response (UPR) is a cellular stress response related to the endoplasmic reticulum. It is a stress response that has been found to be conserved between all mammalian species, as well as yeast and worm organisms. This article focuses on the mammalian response. Th...
Unfolded protein response Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview The unfolded protein response (UPR) is a cellular stress response related to the endoplasmic reticulum. It is a stress response that has been found to be conserved between all mammalian species, as well as yeast and worm organisms...
https://www.wikidoc.org/index.php/Unfolded_protein_response
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wikidoc
Upper motor neuron lesion
Upper motor neuron lesion # Overview An upper motor neuron lesion is a lesion of the neural pathway above the anterior horn cell or motor nuclei of the cranial nerves. This is in contrast to a lower motor neuron lesion, which affects nerve fibers traveling from the anterior horn of the spinal cord to the relevant musc...
Upper motor neuron lesion Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2] Luke Rusowicz-Orazem, B.S. # Overview An upper motor neuron lesion is a lesion of the neural pathway above the anterior horn cell or motor nuclei of the cranial nerves. This is in ...
https://www.wikidoc.org/index.php/Upper_motor_neuron_lesion
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wikidoc
V box gene transcriptions
V box gene transcriptions "The V boxes encompass a leader exon and first intron of the mature transcript." "REV-ERBα and RORa are nuclear receptors rather than bZIP transcription factors like VRI and PDP1ϵ, and they regulate transcription by binding RORE elements rather than V/P-boxes (Bell-Pedersen et al., 2005)." "A...
V box gene transcriptions Editor-In-Chief: Henry A. Hoff "The V boxes encompass a leader exon and first intron of the mature transcript."[1] "REV-ERBα and RORa are nuclear receptors rather than bZIP transcription factors like VRI [target gene: vrille (VRI)] and PDP1ϵ, and they regulate transcription by binding RORE el...
https://www.wikidoc.org/index.php/V_box_gene_transcriptions
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wikidoc
Vaginitis medical therapy
Vaginitis medical therapy # Overview The cause of the infection determines the appropriate treatment. It may include oral or topical antibiotics and/or antifungal creams, antibacterial creams, or similar medications. A cream containing cortisone may also be used to relieve some of the irritation. If an allergic reacti...
Vaginitis medical therapy Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2] # Overview The cause of the infection determines the appropriate treatment. It may include oral or topical antibiotics and/or antifungal creams, antibacterial creams, or similar medications...
https://www.wikidoc.org/index.php/Vaginitis_medical_therapy
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wikidoc
Valacyclovir how supplied
Valacyclovir how supplied # How Supplied VALTREX Caplets (blue, film─coated, capsule─shaped tablets) containing valacyclovir hydrochloride equivalent to 500 mg valacyclovir and printed with "VALTREX 500 mg." Bottle of 30 (NDC 0173-0933-08). Bottle of 90 (NDC 0173-0933-10). Unit dose pack of 100 (NDC 0173-0933-56). VAL...
Valacyclovir how supplied Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2] # How Supplied VALTREX Caplets (blue, film─coated, capsule─shaped tablets) containing valacyclovir hydrochloride equivalent to 500 mg valacyclovir and printed with "VALTREX 500 mg." Bottle ...
https://www.wikidoc.org/index.php/Valacyclovir_how_supplied
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wikidoc
Valacyclovir microbiology
Valacyclovir microbiology # Microbiology Antiviral Activities: The quantitative relationship between the cell culture susceptibility of herpesviruses to antivirals and the clinical response to therapy has not been established in humans, and virus sensitivity testing has not been standardized. Sensitivity testing resul...
Valacyclovir microbiology Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2] # Microbiology Antiviral Activities: The quantitative relationship between the cell culture susceptibility of herpesviruses to antivirals and the clinical response to therapy has not been e...
https://www.wikidoc.org/index.php/Valacyclovir_microbiology
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wikidoc
Velopharyngeal inadequacy
Velopharyngeal inadequacy # Overview Velopharyngeal inadequacy (VPI) is a malfunction of a velopharyngeal mechanism. The velopharyngeal mechanism is responsible for directing the transmission of sound energy and air pressure in both the oral cavity and the nasal cavity. When this mechanism is impaired in some way, the...
Velopharyngeal inadequacy Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Velopharyngeal inadequacy (VPI) is a malfunction of a velopharyngeal mechanism. The velopharyngeal mechanism is responsible for directing the transmission of sound energy and air pressure in both the oral cavity and the nasal cavi...
https://www.wikidoc.org/index.php/Velopharyngeal_inadequacy
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wikidoc
Vhr1p gene transcriptions
Vhr1p gene transcriptions "Transcription of the Saccharomyces cerevisiae vitamin H transporter gene VHT1 is enhanced by low extracellular biotin." "Vhr1p a transcriptional regulator of VHT1 (VHR1 (YIL056w)". "Deletion and linker scanning analyses of the VHT1 promoter revealed the palindromic 18-nucleotide sequence AAT...
Vhr1p gene transcriptions Associate Editor(s)-in-Chief: Henry A. Hoff "Transcription of the Saccharomyces cerevisiae vitamin H transporter gene VHT1 is enhanced by low extracellular biotin."[1] "Vhr1p [is] a transcriptional regulator of VHT1 (VHR1 (YIL056w)".[1] "Deletion and linker scanning analyses of the VHT1 prom...
https://www.wikidoc.org/index.php/Vhr1p_gene_transcriptions
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wikidoc
Viagra for failing hearts
Viagra for failing hearts November 18, 2007 By Benjamin A. Olenchock, M.D. Ph.D. Milan, Italy & Richmond, VA Sildenafil, a type 5 phosphodiasterase inhibitor, was originally designed as a blood pressure medicine before it was found to have beneficial sexual effects. Current research has focused on the role of sildena...
Viagra for failing hearts November 18, 2007 By Benjamin A. Olenchock, M.D. Ph.D. [1] Milan, Italy & Richmond, VA Sildenafil, a type 5 phosphodiasterase inhibitor, was originally designed as a blood pressure medicine before it was found to have beneficial sexual effects. Current research has focused on the role of sil...
https://www.wikidoc.org/index.php/Viagra_for_failing_hearts
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wikidoc
Viral meningitis
Viral meningitis overview # Overview Viral meningitis is a condition in which the layers lining the brain, or meninges, become inflamed due to a viral infection. Meningitis is diagnosed on a history of characteristic symptoms and certain examination findings (e.g. Kernig's sign). Investigations should show an increase...
Viral meningitis overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2] # Overview Viral meningitis is a condition in which the layers lining the brain, or meninges, become inflamed due to a viral infection. Meningitis is diagnosed on a history of characteris...
https://www.wikidoc.org/index.php/Viral_meningitis_overview
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wikidoc
Vitamin D-binding protein
Vitamin D-binding protein Vitamin D-binding protein (DBP), also/originally known as gc-globulin (group-specific component), is a protein that in humans is encoded by the GC gene. # Structure Human GC is a glycosylated alpha-globulin, ~58 kDa in size. Its 458 amino acids are coded for by 1690 nucleotides on chromosome ...
Vitamin D-binding protein Vitamin D-binding protein (DBP), also/originally known as gc-globulin (group-specific component), is a protein that in humans is encoded by the GC gene.[1][2] # Structure Human GC is a glycosylated alpha-globulin, ~58 kDa in size. Its 458 amino acids are coded for by 1690 nucleotides on chro...
https://www.wikidoc.org/index.php/Vitamin_D-binding_protein
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wikidoc
Volatile organic compound
Volatile organic compound Volatile organic compounds (VOCs) are organic chemical compounds that have high enough vapour pressures under normal conditions to significantly vaporize and enter the atmosphere. (The term VOC is also occasionally used as an abbreviation, especially in biological contexts, for "volatile org...
Volatile organic compound Volatile organic compounds (VOCs) are organic chemical compounds that have high enough vapour pressures under normal conditions to significantly vaporize and enter the atmosphere. (The term VOC is also occasionally used as an abbreviation, especially in biological contexts, for "volatile or...
https://www.wikidoc.org/index.php/Volatile_organic_compound
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wikidoc
Voltage-gated ion channel
Voltage-gated ion channel # Overview Voltage-gated ion channels are a class of transmembrane ion channels that are activated by changes in electrical potential difference near the channel; these types of ion channels are especially critical in neurons, but are common in many types of cells. All voltage gates contain ...
Voltage-gated ion channel Editor-in-Chief: Robert G. Schwartz, M.D. [1], Piedmont Physical Medicine and Rehabilitation, P.A.; Associate Editor-In-Chief: Austin B. Schwartz, PhD Candidate, Department of Biophysics, Florida State University # Overview Voltage-gated ion channels are a class of transmembrane ion channels...
https://www.wikidoc.org/index.php/Voltage-gated
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wikidoc
Voriconazole how supplied
Voriconazole how supplied # How Supplied ### Powder for Solution for Injection VFEND I.V. for Injection is supplied in a single use vial as a sterile lyophilized powder equivalent to 200 mg VFEND and 3200 mg sulfobutyl ether beta-cyclodextrin sodium (SBECD). Individually packaged vials of 200 mg VFEND I.V. (NDC 0049-...
Voriconazole how supplied Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2] # How Supplied ### Powder for Solution for Injection VFEND I.V. for Injection is supplied in a single use vial as a sterile lyophilized powder equivalent to 200 mg VFEND and 3200 mg sulf...
https://www.wikidoc.org/index.php/Voriconazole_how_supplied
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wikidoc
Voriconazole microbiology
Voriconazole microbiology # Microbiology ### Mechanism of Action Voriconazole is a triazole antifungal agent. The primary mode of action of voriconazole is the inhibition of fungal cytochrome P-450-mediated 14 alpha-lanosterol demethylation, an essential step in fungal ergosterol biosynthesis. The accumulation of 14 ...
Voriconazole microbiology Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2] # Microbiology ### Mechanism of Action Voriconazole is a triazole antifungal agent. The primary mode of action of voriconazole is the inhibition of fungal cytochrome P-450-mediated 14 al...
https://www.wikidoc.org/index.php/Voriconazole_microbiology
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wikidoc
Women's Health Initiative
Women's Health Initiative The Women's Health Initiative (WHI) was initiated by the National Institutes of Health (NIH) in 1991. The objective of this women's health research initiative was to conduct medical research into some of the major health problems of older women. In particular, clinical trials were designed and...
Women's Health Initiative } The Women's Health Initiative (WHI) was initiated by the National Institutes of Health (NIH) in 1991. The objective of this women's health research initiative was to conduct medical research into some of the major health problems of older women. In particular, clinical trials were designed ...
https://www.wikidoc.org/index.php/WHI
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wikidoc
W box gene transcriptions
W box gene transcriptions "Consistent with its role as a transcriptional repressor, OsWRKY71 binds specifically to functionally defined TGAC-containing W boxes of the Amy32b promoter in electrophoretic mobility shift assays (Zhang et al. 2004)." "Details of auto-regulation or cross-regulation by WRKY factors were provi...
W box gene transcriptions Editor-In-Chief: Henry A. Hoff "Consistent with its role as a transcriptional repressor, OsWRKY71 binds specifically to functionally defined TGAC-containing W boxes of the Amy32b promoter in electrophoretic mobility shift assays (Zhang et al. 2004)."[1] "Details of auto-regulation or cross-re...
https://www.wikidoc.org/index.php/W_box_gene_transcriptions
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wikidoc
Waldeyer's tonsillar ring
Waldeyer's tonsillar ring Waldeyer's tonsillar ring is an anatomical term describing the lymphoid tissue ring located in the pharynx. It was named after the nineteenth century German anatomist Heinrich Wilhelm Gottfried von Waldeyer-Hartz. The ring consists of (from superior to inferior): - Adenoids (also termed pharyn...
Waldeyer's tonsillar ring Waldeyer's tonsillar ring is an anatomical term describing the lymphoid tissue ring located in the pharynx. It was named after the nineteenth century German anatomist Heinrich Wilhelm Gottfried von Waldeyer-Hartz.[1] The ring consists of (from superior to inferior): - Adenoids (also termed ph...
https://www.wikidoc.org/index.php/Waldeyer%27s_ring
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wikidoc
Wernicke's encephalopathy
Wernicke's encephalopathy # Overview Wernicke encephalopathy is a severe syndrome characterised by ataxia, ophthalmoplegia, confusion and loss of short-term memory. It is linked to damage to the medial thalamic nuclei, mammillary bodies, periaqueductal, and periventricular brainstem nuclei , and superior cerebellar ve...
Wernicke's encephalopathy Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: # Overview Wernicke encephalopathy is a severe syndrome characterised by ataxia, ophthalmoplegia, confusion and loss of short-term memory.[1][2] It is linked to damage to the medial thalamic nuclei, mammillary ...
https://www.wikidoc.org/index.php/Wernicke%27s_Encephalopathy
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wikidoc
Wilcoxon signed-rank test
Wilcoxon signed-rank test # Overview The Wilcoxon signed-rank test is a non-parametric alternative to the paired Student's t-test for the case of two related samples or repeated measurements on a single sample. The test is named for Frank Wilcoxon (1892–1965) who, in a single paper, proposed both it and the rank-sum t...
Wilcoxon signed-rank test # Overview The Wilcoxon signed-rank test is a non-parametric alternative to the paired Student's t-test for the case of two related samples or repeated measurements on a single sample. The test is named for Frank Wilcoxon (1892–1965) who, in a single paper, proposed both it and the rank-sum t...
https://www.wikidoc.org/index.php/Wilcoxon_signed-rank_test
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wikidoc
Wilson's disease
Wilson's disease overview # Overview Wilson's disease is a rare autosomal recessive inherited disease that occurs in both children and adults due to copper accumulation in different organs, mainly in the liver and the brain. Wilson's disease is caused by genetic mutations in the ATP7B gene which is responsible for the...
Wilson's disease overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2] # Overview Wilson's disease is a rare autosomal recessive inherited disease that occurs in both children and adults due to copper accumulation in different organs, mainly in the liver ...
https://www.wikidoc.org/index.php/Wilson%27s_disease_overview
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wikidoc
World Medical Association
World Medical Association The World Medical Association (WMA), an international organization of physicians, was formally established on September 17, 1947, pursuant to the resolutions of the First General Assembly of WMA held in Paris, France. In 2007, the WMA had a membership of 84 national medical associations and ...
World Medical Association The World Medical Association (WMA), an international organization of physicians, was formally established on September 17, 1947, pursuant to the resolutions of the First General Assembly of WMA held in Paris, France.[1] In 2007, the WMA had a membership of 84 national medical associations ...
https://www.wikidoc.org/index.php/World_Medical_Association
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wikidoc
X box gene transcriptions
X box gene transcriptions "The so-called X (or X1) box in the promoter of the human MHC class II DRA gene is the binding site for a ubiquitous mammalian sequence-specific DNA-binding protein called RFX, NF-X, NF-Xc, or RFX1 (4,19,23,24,27)." "RFX is MDBP the MDBP (RFX) recognition site region in the DRA promoter can ...
X box gene transcriptions Editor-In-Chief: Henry A. Hoff "The so-called X (or X1) box in the promoter of the human MHC [major histocompatibility complex] class II DRA gene is the binding site for a ubiquitous mammalian sequence-specific DNA-binding protein called RFX, NF-X, NF-Xc, or RFX1 (4,19,23,24,27)."[1] "RFX is ...
https://www.wikidoc.org/index.php/X_box_gene_transcriptions
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wikidoc
Xbp1p gene transcriptions
Xbp1p gene transcriptions Transcription factor for the XhoI site-binding protein 1 protein (Xbp1p) binds to the promoters of CLN1, CYS3, SMF2 induced by stress of starvation to function as a transcriptional repressor. # Human genes # Interactions # Consensus sequences The upstream activating sequence (UAS) for the X...
Xbp1p gene transcriptions Associate Editor(s)-in-Chief: Henry A. Hoff Transcription factor for the XhoI site-binding protein 1 protein (Xbp1p) binds to the promoters of CLN1, CYS3, SMF2 induced by stress of starvation to function as a transcriptional repressor.[1] # Human genes # Interactions # Consensus sequences...
https://www.wikidoc.org/index.php/Xbp1p_gene_transcriptions
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wikidoc
Xenon hexafluoroplatinate
Xenon hexafluoroplatinate Xenon hexafluoroplatinate is the description of the product obtained from the combination of platinum hexafluoride and xenon in an experiment that proved the chemical reactivity of the noble gases. Neil Bartlett at the University of British Columbia formulated the product as "Xe+−", although ...
Xenon hexafluoroplatinate Xenon hexafluoroplatinate is the description of the product obtained from the combination of platinum hexafluoride and xenon in an experiment that proved the chemical reactivity of the noble gases. Neil Bartlett at the University of British Columbia formulated the product as "Xe+[PtF6]−", al...
https://www.wikidoc.org/index.php/Xenon_hexafluoroplatinate
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wikidoc
Y box gene transcriptions
Y box gene transcriptions The "Y-box an inverted CCAAT box, in the promoter region of many genes; this domain is highly conserved in evolution ." # Human genes Gene ID: 4904 is YBX1 Y-box binding protein 1 aka CCAAT-binding transcription factor I subunit A, DNA-binding protein B, Y-box transcription factor, enhancer ...
Y box gene transcriptions Editor-In-Chief: Henry A. Hoff The "Y-box [is] an inverted CCAAT box, in the promoter region of many genes; this domain is highly conserved in evolution [1, 3, 4]."[1] # Human genes Gene ID: 4904 is YBX1 Y-box binding protein 1 aka CCAAT-binding transcription factor I subunit A, DNA-binding ...
https://www.wikidoc.org/index.php/Y_box_gene_transcriptions
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wikidoc
Z box gene transcriptions
Z box gene transcriptions "Both miRNAs map closely on human chromosome 12p13.31 and the stem–loop sequences are separated by only a 338‐base‐pair spacer sequence . This spacer and the putative promoter 600 bp upstream from the hsa‐miR‐200c stem–loop contain six putative binding sequences for ZEB1, two of which were r...
Z box gene transcriptions Editor-In-Chief: Henry A. Hoff "Both miRNAs [miR‐141 and miR‐200c] map closely on human chromosome 12p13.31 and the stem–loop sequences are separated by only a 338‐base‐pair spacer sequence [...]. This spacer and the putative promoter 600 bp upstream from the hsa‐miR‐200c stem–loop contain si...
https://www.wikidoc.org/index.php/Z_box_gene_transcriptions
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wikidoc
Zap1p gene transcriptions
Zap1p gene transcriptions "Zinc homeostasis in yeast is controlled primarily through the regulation of zinc uptake. Transcription of the ZRT1 and ZRT2 zinc transporters increases in zinc-limited cells, and this induction is dependent on the ZAP1 gene. Expression of ZAP1 itself increases in zinc-limited cells. (ZREs) ...
Zap1p gene transcriptions Associate Editor(s)-in-Chief: Henry A. Hoff "Zinc homeostasis in yeast is controlled primarily through the regulation of zinc uptake. Transcription of the ZRT1 and ZRT2 zinc transporters increases in zinc-limited cells, and this induction is dependent on the ZAP1 gene. [...] Expression of ZA...
https://www.wikidoc.org/index.php/Zap1p_gene_transcriptions
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wikidoc
Wolf-Hirschhorn syndrome
Wolf-Hirschhorn syndrome Synonyms and keywords: deletion 4p; 4p- syndrome; chromosome 4p16.3 deletion syndrome; Pitt-Rogers-Danks syndrome; PRDS; Pitt syndrome; Wittwer syndrome # Overview Wolf-Hirschhorn syndrome is a rare disease due to the deletion of the short arm on chromosome 4 which causes severe to profound me...
Wolf-Hirschhorn syndrome Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Synonyms and keywords: deletion 4p; 4p- syndrome; chromosome 4p16.3 deletion syndrome; Pitt-Rogers-Danks syndrome; PRDS; Pitt syndrome; Wittwer syndrome # Overview Wolf-Hirschhorn syndrome is a rare disease due to the deletion of the short ar...
https://www.wikidoc.org/index.php/4p-_syndrome
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wikidoc
60S ribosomal protein L5
60S ribosomal protein L5 60S ribosomal protein L5 is a protein that in humans is encoded by the RPL5 gene. # Function Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurall...
60S ribosomal protein L5 60S ribosomal protein L5 is a protein that in humans is encoded by the RPL5 gene.[1][2] # Function Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 stru...
https://www.wikidoc.org/index.php/60S_ribosomal_protein_L5
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wikidoc
60S ribosomal protein L6
60S ribosomal protein L6 60S ribosomal protein L6 is a protein that in humans is encoded by the RPL6 gene. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct p...
60S ribosomal protein L6 60S ribosomal protein L6 is a protein that in humans is encoded by the RPL6 gene.[1][2][3] Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally ...
https://www.wikidoc.org/index.php/60S_ribosomal_protein_L6
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wikidoc
A1BG gene transcriptions
A1BG gene transcriptions A1BG is the official symbol for GeneID: 1, "A1BG alpha-1-B glycoprotein ", in the National Center for Biotechnology Information (NCBI) gene database for gene-specific information. To access information about this gene, use the "Home - Gene - NCBI" external link and enter "1", without the quotes...
A1BG gene transcriptions Editor-In-Chief: Henry A. Hoff A1BG is the official symbol for GeneID: 1, "A1BG alpha-1-B glycoprotein [ Homo sapiens ]", in the National Center for Biotechnology Information (NCBI) gene database for gene-specific information. To access information about this gene, use the "Home - Gene - NCBI"...
https://www.wikidoc.org/index.php/A1BG_gene_transcription
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wikidoc
Acute coronary syndromes
Acute coronary syndromes Synonyms and keywords: acute coronary syndrome, acute coronary syndromes, ST-elevation myocardial infarction, Non-ST-segment elevation acute coronary syndrome, unstable angina, STEMI, UA, , NSTEMI, NSTE-ACS # Overview Acute coronary syndrome (ACS) refers to a spectrum of conditions resulting f...
Acute coronary syndromes Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mitra Chitsazan, M.D.[2] Yamuna Kondapally, M.B.B.S[3]; Tarek Nafee, M.D. [4]; Sabawoon Mirwais, M.B.B.S, M.D.[5] Synonyms and keywords: acute coronary syndrome, acute coronary syndromes, ST-elevation myocardial ...
https://www.wikidoc.org/index.php/ACS
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wikidoc
Saethre-Chotzen syndrome
Saethre-Chotzen syndrome # Overview Saethre-Chotzen syndrome, also known as acrocephalosyndactyly type 3 (ACS III) and Chotzen syndrome is a very rare congenital syndrome characterised by craniosynostosis (premature closure of one or more of the sutures between the bones of the skull). It is an autosomal dominant diso...
Saethre-Chotzen syndrome # Overview Saethre-Chotzen syndrome, also known as acrocephalosyndactyly type 3 (ACS III) and Chotzen syndrome is a very rare congenital syndrome characterised by craniosynostosis (premature closure of one or more of the sutures between the bones of the skull). It is an autosomal dominant diso...
https://www.wikidoc.org/index.php/ACS_III
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wikidoc
ADP-specific glucokinase
ADP-specific glucokinase In enzymology, an ADP-specific glucokinase (EC 2.7.1.147) also known as ADP-dependent glucokinase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are ADP and D-glucose, whereas its two products are AMP and D-glucose 6-phosphate. This enzyme belongs to ...
ADP-specific glucokinase In enzymology, an ADP-specific glucokinase (EC 2.7.1.147) also known as ADP-dependent glucokinase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are ADP and D-glucose, whereas its two products are AMP and D-glucose 6-phosphate. This enzyme belongs to...
https://www.wikidoc.org/index.php/ADP-specific_glucokinase
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wikidoc
AGCE gene transcriptions
AGCE gene transcriptions Angiotensinogen core promoter element 1 (AGCE1) is an example of a core promoter element that may occur in a DNA sequence for only one gene (the human angiotensinogen gene angiotensin). "he core promoter element 1 (AGCE1) of the human angiotensinogen gene (AGT) ... acts as a critical regulator ...
AGCE gene transcriptions Associate Editor(s)-in-Chief: Henry A. Hoff Angiotensinogen core promoter element 1 (AGCE1) is an example of a core promoter element that may occur in a DNA sequence for only one gene (the human angiotensinogen gene angiotensin). "[T]he core promoter element 1 (AGCE1) of the human angiotensin...
https://www.wikidoc.org/index.php/AGCE_gene_transcriptions
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wikidoc
Porphobilinogen synthase
Porphobilinogen synthase Porphobilinogen synthase (or ALA dehydratase, or aminolevulinate dehydratase) synthesizes porphobilinogen through the asymmetric condensation of two molecules of aminolevulinic acid. All natural tetrapyrroles, including hemes, chlorophylls and vitamin B12, share porphobilinogen as a common prec...
Porphobilinogen synthase Porphobilinogen synthase (or ALA dehydratase, or aminolevulinate dehydratase) synthesizes porphobilinogen through the asymmetric condensation of two molecules of aminolevulinic acid. All natural tetrapyrroles, including hemes, chlorophylls and vitamin B12, share porphobilinogen as a common pre...
https://www.wikidoc.org/index.php/ALA_dehydratase
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wikidoc
AMA Physician Masterfile
AMA Physician Masterfile The American Medical Association (AMA) Physician Masterfile includes current and historical data on all physicians, including AMA members and nonmembers, and graduates of foreign medical schools who reside in the United States and who have met the educational and credentialing requirements nece...
AMA Physician Masterfile The American Medical Association (AMA) Physician Masterfile includes current and historical data on all physicians, including AMA members and nonmembers, and graduates of foreign medical schools who reside in the United States and who have met the educational and credentialing requirements nec...
https://www.wikidoc.org/index.php/AMA_Physician_Masterfile
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wikidoc
Antistreptolysin O titer
Antistreptolysin O titer Antistreptolysin O titre (AS(L)O titre or AS(L)OT) - titre of (serum) antistreptolysin O antibodies; a blood test used to assist in the diagnosis of a streptococcal infection or indicate a past exposure to streptococci. The ASOT helps direct the antimicrobial treatment and is used to assist in ...
Antistreptolysin O titer Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Antistreptolysin O titre (AS(L)O titre or AS(L)OT) - titre of (serum) antistreptolysin O antibodies; a blood test used to assist in the diagnosis of a streptococcal infection or indicate a past exposure to streptococci. The ASOT helps direct t...
https://www.wikidoc.org/index.php/ASO_titer
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wikidoc
Aortic valve replacement
Aortic valve replacement # Overview Aortic valve replacement is a cardiac surgery procedure in which a patient's aortic valve is replaced by a different valve. The aortic valve can be affected by a range of diseases; the valve can either become leaky (aortic insufficiency / regurgitation) or partially blocked (aortic ...
Aortic valve replacement Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Aortic valve replacement is a cardiac surgery procedure in which a patient's aortic valve is replaced by a different valve. The aortic valve can be affected by a range of diseases; the valve can either become leaky (aortic insuffic...
https://www.wikidoc.org/index.php/AVR
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wikidoc
AV reentrant tachycardia
AV reentrant tachycardia Synonyms and keywords: AVRT; AV-reciprocating tachycardia; atrioventricular reentrant tachycardia; circus movement tachycardia # Overview AVRT results from an anatomically distinct atrioventricular connection. The causes, which usually are congenital or genetic, include: Ebstein anomaly, Lown-...
AV reentrant tachycardia Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Varun Kumar, M.B.B.S. [2] Synonyms and keywords: AVRT; AV-reciprocating tachycardia; atrioventricular reentrant tachycardia; circus movement tachycardia # Overview AVRT results from an anatomically distinct atri...
https://www.wikidoc.org/index.php/AVRT
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wikidoc
How to read a guideline?
How to read a guideline? # Class I Conditions for which there is evidence and/or general agreement that a given procedure or treatment is beneficial, useful, and effective. # Class II Conditions for which there is conflicting evidence and/or a divergence of opinion about the usefulness/efficacy of a procedure or trea...
How to read a guideline? Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2] Template:WikiDoc Cardiology News Any recommendations found on these pages are for education use only. Wikidoc is not a substitute for a licensed healthcare provider. Please see the discl...
https://www.wikidoc.org/index.php/A_quick_guide:_How_to_read_a_guideline%3F
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wikidoc
Abandoned child syndrome
Abandoned child syndrome # Overview Abandoned child syndrome is a behavioral or psychological condition that results from the loss of one or both parents. Abandonment may be physical (the parent is not present in the child's life) or emotional (the parent withholds affection, nurturing, or stimulation). Many countrie...
Abandoned child syndrome Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Abandoned child syndrome is a behavioral or psychological condition that results from the loss of one or both parents. Abandonment may be physical (the parent is not present in the child's life) or emotional (the parent withholds a...
https://www.wikidoc.org/index.php/Abandoned_child_syndrome
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wikidoc
Abdominal CSF pseudocyst
Abdominal CSF pseudocyst # Overview Peritoneal pseudocyst is a rare complication of ventriculoperitoneal shunt catheter placement. The time from the last shunting procedure to the development of an abdominal pseudocyst ranges from 3 weeks to 5 years. Cerebrospinal fluid pseudocysts are seen as a thin-walled cystic mas...
Abdominal CSF pseudocyst Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Peritoneal pseudocyst is a rare complication of ventriculoperitoneal shunt catheter placement. The time from the last shunting procedure to the development of an abdominal pseudocyst ranges from 3 weeks to 5 years. Cerebrospinal fl...
https://www.wikidoc.org/index.php/Abdominal_CSF_pseudocyst
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wikidoc
Accessory navicular bone
Accessory navicular bone # Overview An accessory navicular bone is a bone of the foot that occasionally develops abnormally in front of the ankle towards the inside of the foot. This bone is present in approximately 10% of the general population and is usually asymptomatic. When it is symptomatic, surgery may be neces...
Accessory navicular bone Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview An accessory navicular bone is a bone of the foot that occasionally develops abnormally in front of the ankle towards the inside of the foot. This bone is present in approximately 10% of the general population and is usually asympt...
https://www.wikidoc.org/index.php/Accessory_Navicular_bone
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wikidoc
Acetaminophen (infusion)
Acetaminophen (infusion) # Disclaimer WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational content...
Acetaminophen (infusion) Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Adeel Jamil, M.D. [2] # Disclaimer WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is in...
https://www.wikidoc.org/index.php/Acetaminophen_(infusion)
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wikidoc
Fibroblast growth factor
Fibroblast growth factor Fibroblast growth factors, or FGFs, are a family of growth factors involved in wound healing and embryonic development. The FGFs are heparin-binding proteins and interactions with cell-surface associated heparan sulfate proteoglycans have been shown to be essential for FGF signal transduction....
Fibroblast growth factor Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Fibroblast growth factors, or FGFs, are a family of growth factors involved in wound healing and embryonic development. The FGFs are heparin-binding proteins and interactions with cell-surface associated heparan sulfate proteoglycans have bee...
https://www.wikidoc.org/index.php/Acidic_fibroblast_growth_factor
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wikidoc
Landau-Kleffner syndrome
Landau-Kleffner syndrome Synonyms and keywords: Infantile acquired aphasia; acquired epileptic aphasia; aphasia with convulsive disorder # Overview Landau-Kleffner syndrome is a rare, childhood neurological syndrome characterized by the sudden or gradual development of aphasia (the inability to understand or express l...
Landau-Kleffner syndrome For patient information, click here Template:DiseaseDisorder infobox Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2] Synonyms and keywords: Infantile acquired aphasia; acquired epileptic aphasia; aphasia with convulsive ...
https://www.wikidoc.org/index.php/Acquired_eleptiform_aphasia
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wikidoc
Palmoplantar keratoderma
Palmoplantar keratoderma # Overview Palmoplantar keratoderma (PPK) or keratosis palmaris et plantaris is part of a group of disorders of the skin affecting primarily the palms of the hands and soles of the feet. It is characterized by thickening of the palms and the soles of individuals who are affected. # Causes The...
Palmoplantar keratoderma Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2] # Overview Palmoplantar keratoderma (PPK) or keratosis palmaris et plantaris is part of a group of disorders of the skin affecting primarily the palms of the hands and soles of the feet. I...
https://www.wikidoc.org/index.php/Acquired_keratosis
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wikidoc
Activin type 2 receptors
Activin type 2 receptors The activin type 2 receptors belong to a larger TGF-beta receptor family and modulate signals for transforming growth factor beta ligands. These receptors are involved in a host of physiological processes including, growth, cell differentiation, homeostasis, osteogenesis, apoptosis and many oth...
Activin type 2 receptors The activin type 2 receptors belong to a larger TGF-beta receptor family and modulate signals for transforming growth factor beta ligands. These receptors are involved in a host of physiological processes including, growth, cell differentiation, homeostasis, osteogenesis, apoptosis and many ot...
https://www.wikidoc.org/index.php/Activin_type_2_receptors
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wikidoc
Brief psychotic disorder
Brief psychotic disorder Synonyms and keywords: Brief reactive psychosis; hysterical psychosis; reactive schizophrenia; transient psychosis; acute and transient psychotic disorders; stress psychosis; good prognosis schizophrenia; thought disturbances # Overview Brief psychotic disorder is a period of psychosis whose d...
Brief psychotic disorder Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Somal Khan, MD Kiran Singh, M.D. [2] Synonyms and keywords: Brief reactive psychosis; hysterical psychosis; reactive schizophrenia; transient psychosis; acute and transient psychotic disorders; stress psychosis...
https://www.wikidoc.org/index.php/Acute_and_transient_psychotic_disorders
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wikidoc
Admissible decision rule
Admissible decision rule # Overview In classical (frequentist) decision theory, an admissible decision rule is a rule for making a decision that is "better" than any other rule that may compete with it, in a specific sense defined below. Generally speaking, in most decision problems the set of admissible rules is lar...
Admissible decision rule Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview In classical (frequentist) decision theory, an admissible decision rule is a rule for making a decision that is "better" than any other rule that may compete with it, in a specific sense defined below. Generally speaking, in most ...
https://www.wikidoc.org/index.php/Admissible_decision_rule
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wikidoc
Adrenal atrophy
Adrenal atrophy overview # Overview Adrenal atrophy is the shrinkage of adrenal gland due to reduce in size and number of adrenal gland cells. # Historical Perspective We have had many famous cases of adrenal atrophy like president John F. Kennedy, king Henry VIII. # Classification There is no established system for...
Adrenal atrophy overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Maryam Hadipour, M.D.[2] # Overview Adrenal atrophy is the shrinkage of adrenal gland due to reduce in size and number of adrenal gland cells. # Historical Perspective We have had many famous cases of adrenal ...
https://www.wikidoc.org/index.php/Adrenal_atrophy_overview
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wikidoc
Adrenal fatigue
Adrenal fatigue overview # Overview Adrenal Fatigue is a condition of the body in which the adrenal glands are exhausted and unable to produce adequate hormones, notably cortisol, the stress hormone of the body. This condition is currently widely unrecognized by the medical community. However, this fact accompanied by...
Adrenal fatigue overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2] # Overview Adrenal Fatigue is a condition of the body in which the adrenal glands are exhausted and unable to produce adequate hormones, notably cortisol, the stress hormone of the bod...
https://www.wikidoc.org/index.php/Adrenal_fatigue_overview
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wikidoc
Advanced Cell Technology
Advanced Cell Technology Advanced Cell Technology (ACT), a biotechnology company formed in 1994, is involved with therapeutic cloning and the cloning of animals. Among the animals it has cloned are transgenic cows. ACT's Chief Scientific Officer is Dr. Michael D. West, who also serves as the Chairman of the Board. He...
Advanced Cell Technology Advanced Cell Technology (ACT), a biotechnology company formed in 1994, is involved with therapeutic cloning and the cloning of animals. Among the animals it has cloned are transgenic cows. [1] ACT's Chief Scientific Officer is Dr. Michael D. West, who also serves as the Chairman of the Board...
https://www.wikidoc.org/index.php/Advanced_Cell_Technology
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wikidoc
Blastic NK cell lymphoma
Blastic NK cell lymphoma Synonyms and keywords: Agranular CD4+CD56+ hematodermic neoplasm; CD4+CD56+ hematodermic neoplasm; HDT; Blastic plasmacytoid dendritic cell neoplasm; BPDCN; Blastic natural killer cell lymphoma # Overview Blastic natural killer cell lymphoma was first discovered by Adachi, an American hematolo...
Blastic NK cell lymphoma Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Synonyms and keywords: Agranular CD4+CD56+ hematodermic neoplasm; CD4+CD56+ hematodermic neoplasm; HDT; Blastic plasmacytoid dendritic cell neoplasm; BPDCN; Blastic natural killer cell lymphoma # Overview Blastic natural killer cell lymphoma ...
https://www.wikidoc.org/index.php/Agranular_CD4%2BCD56%2B_hematodermic_neoplasm
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wikidoc
Albendazole how supplied
Albendazole how supplied # How Supplied ALBENZA is supplied as 200 mg, white to off-white, circular, biconvex, bevel-edged, film coated TILTAB tablet embossed "ap" and "550". They are supplied as follows: Bottles of 2 NDC 52054-550-22 Bottles of 28 NDC 52054-550-28 Store at 20° to 25°C (68° to 77°F) . ALBE...
Albendazole how supplied Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # How Supplied ALBENZA is supplied as 200 mg, white to off-white, circular, biconvex, bevel-edged, film coated TILTAB tablet embossed "ap" and "550". They are supplied as follows: Bottles of 2 NDC 52054-550-22 Bottles of 28 NDC 52...
https://www.wikidoc.org/index.php/Albendazole_how_supplied
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wikidoc
Chédiak-Higashi syndrome
Chédiak-Higashi syndrome For patient information on this page, click here Synonyms and keywords: Oculocutaneous albinism with leukocyte defect; Beguez Cesar disease; Chediak-Steinbrinck-Higashi Syndrome; leukocytic anomaly albinism # Overview Chédiak-Higashi syndrome is a rare childhood autosomal recessive disorder th...
Chédiak-Higashi syndrome Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Assosciate Editor(s)-In-Chief: Prashanth Saddala M.B.B.S; Raviteja Guddeti, M.B.B.S. [2] For patient information on this page, click here Synonyms and keywords: Oculocutaneous albinism with leukocyte defect; Beguez Cesar disease; Chediak-Stein...
https://www.wikidoc.org/index.php/Albinism_immunodeficiency
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wikidoc
McCune-Albright syndrome
McCune-Albright syndrome # Overview McCune-Albright syndrome is a rare genetic disorder caused by an activating mutation of the GNAS gene resulting in various phenotypic presentations. McCune-Albright syndrome typically presents with the triad of fibrous dysplasia, precocious puberty and café au lait spots in both gen...
McCune-Albright syndrome Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dushka Riaz, MD # Overview McCune-Albright syndrome is a rare genetic disorder caused by an activating mutation of the GNAS gene resulting in various phenotypic presentations. McCune-Albright syndrome typically...
https://www.wikidoc.org/index.php/Albright%27s_Disease
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wikidoc
Wiskott-Aldrich syndrome
Wiskott-Aldrich syndrome Synonyms and keywords: Aldrich syndrome # Overview Wiskott-Aldrich syndrome (WAS) is a rare X-linked recessive disease characterized by eczema, thrombocytopenia (low platelet counts), immune deficiency, and bloody diarrhea (due to the low platelet counts). It is also sometimes called the ecze...
Wiskott-Aldrich syndrome Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chandrakala Yannam, MD [2]; Syed Hassan A. Kazmi BSc, MD [3]; Cafer Zorkun, M.D., Ph.D. [4] Synonyms and keywords: Aldrich syndrome # Overview Wiskott-Aldrich syndrome (WAS) is a rare X-linked recessive disease...
https://www.wikidoc.org/index.php/Aldrich_syndrome
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wikidoc
Alendronate how supplied
Alendronate how supplied # How supplied Tablets FOSAMAX, 5 mg Tablets FOSAMAX, 10 mg Tablets FOSAMAX, 35 mg Tablets FOSAMAX, 40 mg Tablets FOSAMAX, 70 mg Storage ## Tablets FOSAMAX, 5 mg Tablets FOSAMAX, 5 mg, are white, round, uncoated tablets with an -utline of a bone image on one side and code MRK 925 on the other...
Alendronate how supplied Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # How supplied Tablets FOSAMAX, 5 mg Tablets FOSAMAX, 10 mg Tablets FOSAMAX, 35 mg Tablets FOSAMAX, 40 mg Tablets FOSAMAX, 70 mg Storage ## Tablets FOSAMAX, 5 mg Tablets FOSAMAX, 5 mg, are white, round, uncoated tablets with an outline of a ...
https://www.wikidoc.org/index.php/Alendronate_how_supplied