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wikidoc
Lecithin–cholesterol acyltransferase
Lecithin–cholesterol acyltransferase Lecithin–cholesterol acyltransferase (LCAT, also called phosphatidylcholine–sterol O-acyltransferase) is an enzyme that converts free cholesterol into cholesteryl ester (a more hydrophobic form of cholesterol), which is then sequestered into the core of a lipoprotein particle, event...
Lecithin–cholesterol acyltransferase Lecithin–cholesterol acyltransferase (LCAT, also called phosphatidylcholine–sterol O-acyltransferase) is an enzyme that converts free cholesterol into cholesteryl ester (a more hydrophobic form of cholesterol), which is then sequestered into the core of a lipoprotein particle, even...
https://www.wikidoc.org/index.php/Lecithin%E2%80%93cholesterol_acyltransferase
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wikidoc
Legg-Calvé-Perthes syndrome
Legg-Calvé-Perthes syndrome overview # Overview Legg-Calvé-Perthes syndrome is a degenerative disease of the hip joint, where a loss of bone mass leads to some degree of collapse of the hip joint, that is, to deformity of the ball of the femur and the surface of the hip socket. The disease is typically found in young...
Legg-Calvé-Perthes syndrome overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Legg-Calvé-Perthes syndrome is a degenerative disease of the hip joint, where a loss of bone mass leads to some degree of collapse of the hip joint, that is, to deformity of the ball of the femur and the surface of the ...
https://www.wikidoc.org/index.php/Legg-Calv%C3%A9-Perthes_syndrome_overview
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wikidoc
Levonorgestrel and Ethinyl estradiol
Levonorgestrel and Ethinyl estradiol # Disclaimer WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educati...
Levonorgestrel and Ethinyl estradiol Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Deepika Beereddy, MBBS [2] # Disclaimer WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provide...
https://www.wikidoc.org/index.php/Levonorgestrel_and_Ethinyl_estradiol
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wikidoc
Lightheadedness and vertigo
Lightheadedness and vertigo overview # Overview Lightheadedness is a common and often unpleasant sensation of dizziness and/or feeling that one may be about to faint, which may be transient, recurrent, or occasionally chronic. In some cases, the individual may feel as though his or her head is weightless. It can be ...
Lightheadedness and vertigo overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2] # Overview Lightheadedness is a common and often unpleasant sensation of dizziness and/or feeling that one may be about to faint, which may be transient, recurrent, or occasionally chronic. In some cases, the individual may feel...
https://www.wikidoc.org/index.php/Lightheadedness_and_vertigo_overview
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wikidoc
Lincomycin dosage and administration
Lincomycin dosage and administration # DOSAGE AND ADMINISTRATION If significant diarrhea occurs during therapy, this antibiotic should be discontinued. (See WARNING box.) ## INTRAMUSCULAR Adults Serious infections—600 mg (2 mL) intramuscularly every 24 hours. More severe infections—600 mg (2 mL) intramuscularly every...
Lincomycin dosage and administration Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Abdurahman Khalil, M.D. [2] # DOSAGE AND ADMINISTRATION If significant diarrhea occurs during therapy, this antibiotic should be discontinued. (See WARNING box.) ## INTRAMUSCULAR Adults Serious inf...
https://www.wikidoc.org/index.php/Lincomycin_dosage_and_administration
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wikidoc
List of drugs affected by grapefruit
List of drugs affected by grapefruit # Overview Grapefruit and grapefruit juice has the potential to interaction with numerous drugs. This is due to the fruit's relatively high concentration of naringin, bergamottin, and dihydroxybergamottin, which interfere with the intestinal enzyme cytochrome P450 isoform CYP3A4. ...
List of drugs affected by grapefruit Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Grapefruit and grapefruit juice has the potential to interaction with numerous drugs. This is due to the fruit's relatively high concentration of naringin, bergamottin, and dihydroxybergamottin, which interfere with th...
https://www.wikidoc.org/index.php/List_of_drugs_affected_by_grapefruit
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wikidoc
Long QT syndrome laboratory findings
Long QT syndrome laboratory findings # Overview An elevated/reduced concentration of serum/blood/urinary/CSF/other is diagnostic of . OR Laboratory findings consistent with the diagnosis of include , , and . OR is usually normal for patients with . OR Some patients with may have elevated/reduced concentration of ,...
Long QT syndrome laboratory findings Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]; Associate Editor(s)-in-Chief: # Overview An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name]. OR Laboratory findings consistent with the diagnosis of [disease name] includ...
https://www.wikidoc.org/index.php/Long_QT_syndrome_laboratory_findings
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wikidoc
Lorcaserin Hydrochloride Hemihydrate
Lorcaserin Hydrochloride Hemihydrate # Disclaimer WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educati...
Lorcaserin Hydrochloride Hemihydrate Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Stefano Giannoni [2] # Disclaimer WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. Wi...
https://www.wikidoc.org/index.php/Lorcaserin
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wikidoc
Luteinizing hormone beta polypeptide
Luteinizing hormone beta polypeptide Luteinizing hormone subunit beta also known as lutropin subunit beta or LHβ is a polypeptide that in association with an alpha subunit common to all gonadotropin hormones forms the reproductive signaling molecule luteinizing hormone. In humans it is encoded by the LHB gene. # Gene...
Luteinizing hormone beta polypeptide Luteinizing hormone subunit beta also known as lutropin subunit beta or LHβ is a polypeptide that in association with an alpha subunit common to all gonadotropin hormones forms the reproductive signaling molecule luteinizing hormone. In humans it is encoded by the LHB gene.[1][2] ...
https://www.wikidoc.org/index.php/Luteinizing_hormone_beta_polypeptide
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wikidoc
Lybalvi (Olanzapine and Samidorphan)
Lybalvi (Olanzapine and Samidorphan) # Disclaimer WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educati...
Lybalvi (Olanzapine and Samidorphan) Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Tejasvi Aryaputra # Disclaimer WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiD...
https://www.wikidoc.org/index.php/Lybalvi_(Olanzapine_and_Samidorphan)
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wikidoc
Lymphangiomyomatosis medical therapy
Lymphangiomyomatosis medical therapy Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing. # Overview # Medical Therapy The association of LAM with women of childbearing age suggests that hormonal stimulation plays a role in the disease process, and several approaches to t...
Lymphangiomyomatosis medical therapy Template:Lymphangiomyomatosis Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing. # Overview # Medical Therapy The association of LAM with women of childbearing age suggests that hormonal stimulation plays a role in the disease proce...
https://www.wikidoc.org/index.php/Lymphangiomyomatosis_medical_therapy
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wikidoc
Muscarinic acetylcholine receptor M1
Muscarinic acetylcholine receptor M1 The muscarinic acetylcholine receptor M1, also known as the cholinergic receptor, muscarinic 1, is a muscarinic receptor that in humans is encoded by the CHRM1 gene. It is localized to 11q13. This receptor is found mediating slow EPSP at the ganglion in the postganglionic nerve, is ...
Muscarinic acetylcholine receptor M1 The muscarinic acetylcholine receptor M1, also known as the cholinergic receptor, muscarinic 1, is a muscarinic receptor that in humans is encoded by the CHRM1 gene.[1] It is localized to 11q13.[1] This receptor is found mediating slow EPSP at the ganglion in the postganglionic ner...
https://www.wikidoc.org/index.php/M1_receptor
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wikidoc
Muscarinic acetylcholine receptor M2
Muscarinic acetylcholine receptor M2 The muscarinic acetylcholine receptor M2, also known as the cholinergic receptor, muscarinic 2, is a muscarinic acetylcholine receptor that in humans is encoded by the CHRM2 gene. Multiple alternatively spliced transcript variants have been described for this gene. # Function ## H...
Muscarinic acetylcholine receptor M2 The muscarinic acetylcholine receptor M2, also known as the cholinergic receptor, muscarinic 2, is a muscarinic acetylcholine receptor that in humans is encoded by the CHRM2 gene.[1] Multiple alternatively spliced transcript variants have been described for this gene.[1] # Functio...
https://www.wikidoc.org/index.php/M2_receptor
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Muscarinic acetylcholine receptor M3
Muscarinic acetylcholine receptor M3 The muscarinic acetylcholine receptor, also known as cholinergic/acetylcholine receptor M3, or the muscarinic 3, is a muscarinic acetylcholine receptor encoded by the human gene CHRM3. The M3 muscarinic receptors are located at many places in the body, e.g., smooth muscles, the endo...
Muscarinic acetylcholine receptor M3 The muscarinic acetylcholine receptor, also known as cholinergic/acetylcholine receptor M3, or the muscarinic 3, is a muscarinic acetylcholine receptor encoded by the human gene CHRM3.[1] The M3 muscarinic receptors are located at many places in the body, e.g., smooth muscles, the ...
https://www.wikidoc.org/index.php/M3_receptor
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wikidoc
mRNA (guanine-N7-)-methyltransferase
mRNA (guanine-N7-)-methyltransferase In enzymology, a mRNA (guanine-N7-)-methyltransferase also known as mRNA cap guanine-N7 methyltransferase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are S-adenosyl methionine and G(5')pppR-RNA, whereas its two products are S-adenosylhom...
mRNA (guanine-N7-)-methyltransferase In enzymology, a mRNA (guanine-N7-)-methyltransferase also known as mRNA cap guanine-N7 methyltransferase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are S-adenosyl methionine and G(5')pppR-RNA, whereas its two products are S-adenosylho...
https://www.wikidoc.org/index.php/MRNA_(guanine-N7-)-methyltransferase
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wikidoc
Macrophage colony-stimulating factor
Macrophage colony-stimulating factor The colony stimulating factor 1 (CSF1), also known as macrophage colony-stimulating factor (M-CSF), is a secreted cytokine which causes hematopoietic stem cells to differentiate into macrophages or other related cell types. Eukaryotic cells also produce M-CSF in order to combat inte...
Macrophage colony-stimulating factor The colony stimulating factor 1 (CSF1), also known as macrophage colony-stimulating factor (M-CSF), is a secreted cytokine which causes hematopoietic stem cells to differentiate into macrophages or other related cell types. Eukaryotic cells also produce M-CSF in order to combat int...
https://www.wikidoc.org/index.php/Macrophage-colony_stimulating_factor
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wikidoc
Magnetic resonance molecular imaging
Magnetic resonance molecular imaging # Introduction Magnetic resonance imaging (MRI) is regularly used to construct an image based on the intrinsic contrast provided from the relaxation of spin of hydrogen atoms. These images provide an accurate anatomical picture that has greatly advanced health care today. Clinicall...
Magnetic resonance molecular imaging Editor in Chief: Omar Zurkiya, M.D., Ph.D. [1] # Introduction Magnetic resonance imaging (MRI) is regularly used to construct an image based on the intrinsic contrast provided from the relaxation of spin of hydrogen atoms. These images provide an accurate anatomical picture that h...
https://www.wikidoc.org/index.php/Magnetic_resonance_molecular_imaging
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wikidoc
Malonyl-CoA decarboxylase deficiency
Malonyl-CoA decarboxylase deficiency Malonyl-CoA decarboxylase deficiency (or Malonic aciduria) is an autosomal recessive metabolic disorder caused by a genetic mutation which disrupts the activity of Malonyl-Coa decarboxylase. This enzyme breaks down Malonyl-CoA (a fatty acid precursor and a fatty acid oxidation block...
Malonyl-CoA decarboxylase deficiency Malonyl-CoA decarboxylase deficiency (or Malonic aciduria) is an autosomal recessive metabolic disorder caused by a genetic mutation which disrupts the activity of Malonyl-Coa decarboxylase. This enzyme breaks down Malonyl-CoA (a fatty acid precursor and a fatty acid oxidation bloc...
https://www.wikidoc.org/index.php/Malonic_aciduria
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wikidoc
Material properties (thermodynamics)
Material properties (thermodynamics) The thermodynamic properties of materials are intensive thermodynamic parameters which are specific to a given material. Each is directly related to a second order differential of a thermodynamic potential. Examples for a simple 1-component system are: - Compressibility (or its inve...
Material properties (thermodynamics) Template:Thermodynamic equations The thermodynamic properties of materials are intensive thermodynamic parameters which are specific to a given material. Each is directly related to a second order differential of a thermodynamic potential. Examples for a simple 1-component system a...
https://www.wikidoc.org/index.php/Material_properties_(thermodynamics)
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wikidoc
Mebendazole warnings and precautions
Mebendazole warnings and precautions # Warnings and Precautions ## Warnings There is no evidence that mebendazole, even at high doses, is effective for hydatid disease. There have been rare reports of neutropenia and agranulocytosis when mebendazole was taken for prolonged periods and at dosages substantially above t...
Mebendazole warnings and precautions Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Warnings and Precautions ## Warnings There is no evidence that mebendazole, even at high doses, is effective for hydatid disease. There have been rare reports of neutropenia and agranulocytosis when mebendazole was taken for pr...
https://www.wikidoc.org/index.php/Mebendazole_warnings_and_precautions
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wikidoc
Medical education in the Philippines
Medical education in the Philippines Medical education in the Philippines is principally offered and developed by accredited and government recognized medical schools in the country. The Philippine medical schools are graduate schools offering the Doctor of Medicine (M.D.) degree. The M.D. is a four-year professional d...
Medical education in the Philippines Medical education in the Philippines is principally offered and developed by accredited and government recognized medical schools in the country. The Philippine medical schools are graduate schools offering the Doctor of Medicine (M.D.) degree. The M.D. is a four-year professional ...
https://www.wikidoc.org/index.php/Medical_education_in_the_Philippines
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wikidoc
Medical school in the United Kingdom
Medical school in the United Kingdom In the United Kingdom, medical school generally refers to a department within a university which is involved in the education of future medical practitioners. All leading British medical schools are in the government sector and their core purpose is to train doctors on behalf of th...
Medical school in the United Kingdom In the United Kingdom, medical school generally refers to a department within a university which is involved in the education of future medical practitioners. All leading British medical schools are in the government sector and their core purpose is to train doctors on behalf of t...
https://www.wikidoc.org/index.php/Medical_school_(United_Kingdom)
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wikidoc
Mefenamic Acid (patient information)
Mefenamic Acid (patient information) # IMPORTANT WARNING People who take nonsteroidal anti-inflammatory medications (NSAIDs) (other than aspirin) such as mefenamic acid may have a higher risk of having a heart attack or a stroke than people who do not take these medications. These events may happen without warning and...
Mefenamic Acid (patient information) Template:Drug header # IMPORTANT WARNING People who take nonsteroidal anti-inflammatory medications (NSAIDs) (other than aspirin) such as mefenamic acid may have a higher risk of having a heart attack or a stroke than people who do not take these medications. These events may happ...
https://www.wikidoc.org/index.php/Mefenamic_Acid
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wikidoc
Mefloquine dosage and administration
Mefloquine dosage and administration # Dosage And Administration ## Malaria Treatment in Adults Treatment of mild to moderate malaria in adults caused by mefloquine-susceptible strains of P. falciparum or by P. vivax: Dosage: Five tablets (1250 mg) mefloquine hydrochloride to be given as a single oral dose. The drug ...
Mefloquine dosage and administration Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chetan Lokhande, M.B.B.S [2] # Dosage And Administration ## Malaria Treatment in Adults Treatment of mild to moderate malaria in adults caused by mefloquine-susceptible strains of P. falciparum or ...
https://www.wikidoc.org/index.php/Mefloquine_dosage_and_administration
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wikidoc
Meigs syndrome (patient information)
Meigs syndrome (patient information) For the WikiDoc page on this topic, click here # Overview Meigs' syndrome is characterized as clinical triad: benign ovarian tumor, ascites, and pleural effusion. It is rare before 40 years of age and becomes more frequent as the years progress. The ovarian tumor is usually a fibro...
Meigs syndrome (patient information) For the WikiDoc page on this topic, click here Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Maria Fernanda Villarreal, M.D. [2] # Overview Meigs' syndrome is characterized as clinical triad: benign ovarian tumor, ascites, and pleural effusion. It is rare before 40 years of a...
https://www.wikidoc.org/index.php/Meigs_syndrome_(patient_information)
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wikidoc
Menkes disease (patient information)
Menkes disease (patient information) For the WikiDoc page for this topic, click here # Overview Menkes syndrome is an inborn error of metabolism in which cells in the body cannot absorb enough copper. # What are the symptoms of Menkes disease? - Bone spurs - Brittle, kinky hair - Feeding difficulties - Irritability -...
Menkes disease (patient information) For the WikiDoc page for this topic, click here Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Assistant Editor-in-Chief: Alexandra M. Palmer # Overview Menkes syndrome is an inborn error of metabolism in which cells in the body cannot absorb enough copper. # What are the sy...
https://www.wikidoc.org/index.php/Menkes_disease_(patient_information)
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wikidoc
Mercaptopurine (patient information)
Mercaptopurine (patient information) # About your treatment Your doctor has ordered the drug mercaptopurine to help treat your illness. The drug is taken by mouth in tablet form. This medication is used to treat: - leukemia This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more ...
Mercaptopurine (patient information) Template:Drug header # About your treatment Your doctor has ordered the drug mercaptopurine to help treat your illness. The drug is taken by mouth in tablet form. This medication is used to treat: - leukemia This medication is sometimes prescribed for other uses; ask your doctor o...
https://www.wikidoc.org/index.php/Mercaptopurine_(patient_information)
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wikidoc
Metaproterenol (patient information)
Metaproterenol (patient information) # Why this medication is prescribed Metaproterenol is used to prevent and treat wheezing, shortness of breath, and troubled breathing caused by asthma, chronic bronchitis, emphysema, and other lung diseases. It relaxes and opens air passages in the lungs, making it easier to breath...
Metaproterenol (patient information) Template:Drug header # Why this medication is prescribed Metaproterenol is used to prevent and treat wheezing, shortness of breath, and troubled breathing caused by asthma, chronic bronchitis, emphysema, and other lung diseases. It relaxes and opens air passages in the lungs, maki...
https://www.wikidoc.org/index.php/Metaproterenol_(patient_information)
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Methamphetamine detailed information
Methamphetamine detailed information Methamphetamine (methylamphetamine or desoxyephedrine), popularly shortened to meth and also nicknamed "ice" and Tina, is a psychostimulant and sympathomimetic drug. The dextrorotatory isomer dextromethamphetamine can be prescribed to treat attention-deficit hyperactivity disorder, ...
Methamphetamine detailed information Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2] Template:Otheruses4 Methamphetamine (methylamphetamine or desoxyephedrine), popularly shortened to meth and also nicknamed "ice" and Tina, is a psychostimulant and sympathomimetic drug. The dextrorotatory isomer dextromethamphetami...
https://www.wikidoc.org/index.php/Methamphetamine_detailed_information
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wikidoc
Methylphenidate detailed information
Methylphenidate detailed information Methylphenidate (MPH) is a prescription stimulant commonly used to treat Attention-deficit hyperactivity disorder, or ADHD. It is also one of the primary drugs used to treat the daytime drowsiness symptoms of narcolepsy and chronic fatigue syndrome. The drug is seeing early use to t...
Methylphenidate detailed information Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Methylphenidate (MPH) is a prescription stimulant commonly used to treat Attention-deficit hyperactivity disorder, or ADHD. It is also one of the primary drugs used to treat the daytime drowsiness symptoms of narcolepsy and chronic...
https://www.wikidoc.org/index.php/Methylphenidate_detailed_information
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wikidoc
Micafungin dosage and administration
Micafungin dosage and administration # Dosage and Administration Do not mix or co-infuse Mycamine with other medications. Mycamine has been shown to precipitate when mixed directly with a number of other commonly used medications. The recommended doses for adult patients based on indications are shown in Table 1. ## ...
Micafungin dosage and administration Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2] # Dosage and Administration Do not mix or co-infuse Mycamine with other medications. Mycamine has been shown to precipitate when mixed directly with a number of other commonly ...
https://www.wikidoc.org/index.php/Micafungin_dosage_and_administration
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Miconazole dosage and administration
Miconazole dosage and administration # Dosage And Administration ### Basic Dosing Information The recommended dosing schedule for ORAVIG is the application of one 50 mg buccal tablet to the upper gum region (canine fossa) once daily for 14 consecutive days. ### Administration Instructions - ORAVIG should be applied ...
Miconazole dosage and administration Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2] # Dosage And Administration ### Basic Dosing Information The recommended dosing schedule for ORAVIG is the application of one 50 mg buccal tablet to the upper gum region (cani...
https://www.wikidoc.org/index.php/Miconazole_dosage_and_administration
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wikidoc
Minoxidil oral (patient information)
Minoxidil oral (patient information) # IMPORTANT WARNING Minoxidil may increase chest pain (angina) or cause other heart problems. It is important that you keep all appointments with your doctor so that you can be monitored for any symptoms or changes. If chest pain occurs or worsens while you are taking this medicati...
Minoxidil oral (patient information) Template:Drug header # IMPORTANT WARNING Minoxidil may increase chest pain (angina) or cause other heart problems. It is important that you keep all appointments with your doctor so that you can be monitored for any symptoms or changes. If chest pain occurs or worsens while you ar...
https://www.wikidoc.org/index.php/Minoxidil_Oral
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wikidoc
Mucinous cystadenocarcinoma
Mucinous cystadenocarcinoma overview # Overview Mucinous cystadenocarcinoma of the renal pelvis was first described in 1960 by Hasebe et al. Mucinous cystadenocarcinoma is one of the most aggressive forms of cancer. KRAS mutations are found in mucinous carcinomas. The organs involved in pathogenesis of mucinous cystad...
Mucinous cystadenocarcinoma overview For patient information, click here Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Qurrat-ul-ain Abid, M.D.[2], Ammu Susheela, M.D. [3] # Overview Mucinous cystadenocarcinoma of the renal pelvis was first described in 1960 by Hasebe et al. Muci...
https://www.wikidoc.org/index.php/Mucinous_cystadenocarcinoma_overview
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wikidoc
Muscarinic acetylcholine receptor M4
Muscarinic acetylcholine receptor M4 The muscarinic acetylcholine receptor M4, also known as the cholinergic receptor, muscarinic 4 (CHRM4), is a protein that, in humans, is encoded by the CHRM4 gene. # Function M4 muscarinic receptors are coupled to Gi/o heterotrimeric proteins. They function as inhibitory autorecep...
Muscarinic acetylcholine receptor M4 The muscarinic acetylcholine receptor M4, also known as the cholinergic receptor, muscarinic 4 (CHRM4), is a protein that, in humans, is encoded by the CHRM4 gene.[1][2] # Function M4 muscarinic receptors are coupled to Gi/o heterotrimeric proteins.[3] They function as inhibitory...
https://www.wikidoc.org/index.php/Muscarinic_acetylcholine_receptor_M4
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wikidoc
Myeloproliferative neoplasm
Myeloproliferative neoplasm overview # Overview Myeloproliferative neoplasm are a group of eight disease subtypes of the bone marrow in which excess cells are produced. Myeloproliferative neoplasm may be classified according to the World Health Organization into eight subtypes, including polycythemia vera, essential ...
Myeloproliferative neoplasm overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2] Shyam Patel [3] # Overview Myeloproliferative neoplasm are a group of eight disease subtypes of the bone marrow in which excess cells are produced. Myeloproliferative neopla...
https://www.wikidoc.org/index.php/Myeloproliferative_disease_overview
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wikidoc
Nabothian cyst (patient information)
Nabothian cyst (patient information) For the WikiDoc page for this topic, click here # Overview A nabothian cyst is a mucus-filled lump on the surface of the cervix. # What are the symptoms of Nabothian cyst? Each nabothian cyst appears as a small, white raised bump. There can be more than one. # What causes Nabothi...
Nabothian cyst (patient information) For the WikiDoc page for this topic, click here Editor-in-Chief: C. Michael Gibson, M.S.,M.D. [1] Phone:617-632-7753; Associate Editor(s)-In-Chief: Lakshmi Gopalakrishnan, M.B.B.S. # Overview A nabothian cyst is a mucus-filled lump on the surface of the cervix. # What are the sym...
https://www.wikidoc.org/index.php/Nabothian_cyst_(patient_information)
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Naratriptan warnings and precautions
Naratriptan warnings and precautions # Warnings Naratriptan tablets should only be used where a clear diagnosis of migraine has been established. ### Risk of Myocardial Ischemia and/or Infarction and Other Adverse Cardiac Events Because of the potential of this class of compounds (5-HT1B/1D agonists) to cause coronar...
Naratriptan warnings and precautions Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Warnings Naratriptan tablets should only be used where a clear diagnosis of migraine has been established. ### Risk of Myocardial Ischemia and/or Infarction and Other Adverse Cardiac Events Because of the potential of this clas...
https://www.wikidoc.org/index.php/Naratriptan_warnings_and_precautions
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National Institutes of Health campus
National Institutes of Health campus The National Institutes of Health (NIH) campus is located in Bethesda, Maryland. Most of the institutes house their Divisions of Intramural Research on this campus spread out among various buildings. # Location The campus is located between Old Georgetown Road on the west, Wisconsi...
National Institutes of Health campus The National Institutes of Health (NIH) campus is located in Bethesda, Maryland. Most of the institutes house their Divisions of Intramural Research on this campus spread out among various buildings. # Location The campus is located between Old Georgetown Road on the west, Wiscons...
https://www.wikidoc.org/index.php/National_Institutes_of_Health_campus
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Nelfinavir dosage and administration
Nelfinavir dosage and administration # Dosage and Administration - Adults and Adolescents (13 years and older) The recommended dose is 1250 mg (five 250 mg tablets or two 625 mg tablets) twice daily or 750 mg (three 250 mg tablets) three times daily. VIRACEPT should be taken with a meal. Patients unable to swallow the...
Nelfinavir dosage and administration Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2] # Dosage and Administration - Adults and Adolescents (13 years and older) The recommended dose is 1250 mg (five 250 mg tablets or two 625 mg tablets) twice daily or 750 mg...
https://www.wikidoc.org/index.php/Nelfinavir_dosage_and_administration
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Nevirapine dosage and administration
Nevirapine dosage and administration # Dosage And Administration ## General Dosing Considerations VIRAMUNE XR tablets must be swallowed whole and must not be chewed, crushed, or divided. Children should be assessed for their ability to swallow tablets before prescribing VIRAMUNE XR tablets. VIRAMUNE XR can be taken w...
Nevirapine dosage and administration Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2] # Dosage And Administration ## General Dosing Considerations VIRAMUNE XR tablets must be swallowed whole and must not be chewed, crushed, or divided. Children should be assessed...
https://www.wikidoc.org/index.php/Nevirapine_dosage_and_administration
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Niacin/Simvastatin adverse reactions
Niacin/Simvastatin adverse reactions # Adverse Reactions ## Overview In a controlled clinical study, 14% of patients randomized to SIMCOR discontinued therapy due to an adverse event. Flushing episodes (i.e., warmth, redness, itching and/or tingling) were the most common treatment-emergent adverse reactions, occurrin...
Niacin/Simvastatin adverse reactions Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2] # Adverse Reactions ## Overview In a controlled clinical study, 14% of patients randomized to SIMCOR discontinued therapy due to an adverse event. Flushing episodes (i.e., warmt...
https://www.wikidoc.org/index.php/Niacin/Simvastatin_adverse_reactions
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Niacin/Simvastatin contraindications
Niacin/Simvastatin contraindications # Contraindications SIMCOR is contraindicated in the following conditions: - Active liver disease, which may include unexplained persistent elevations in hepatic transaminase levels - Patients with active peptic ulcer disease - Patients with arterial bleeding - Concomitant adminis...
Niacin/Simvastatin contraindications Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2] # Contraindications SIMCOR is contraindicated in the following conditions: - Active liver disease, which may include unexplained persistent elevations in hepatic transaminase lev...
https://www.wikidoc.org/index.php/Niacin/Simvastatin_contraindications
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Niacin/Simvastatin drug interactions
Niacin/Simvastatin drug interactions # Drug Interactions No drug interaction studies were conducted with SIMCOR. However, the following interactions have been noted with the individual components of SIMCOR: Simvastatin ## Strong CYP3A4 Inhibitors, Cyclosporine, or Danazol Strong CYP3A4 inhibitors: Simvastatin, like s...
Niacin/Simvastatin drug interactions Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2] # Drug Interactions No drug interaction studies were conducted with SIMCOR. However, the following interactions have been noted with the individual components of SIMCOR: Simvasta...
https://www.wikidoc.org/index.php/Niacin/Simvastatin_drug_interactions
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Nitrofurantoin indications and usage
Nitrofurantoin indications and usage # Indications and Usage Macrobid is indicated only for the treatment of acute uncomplicated urinary tract infections (acute cystitis) caused by susceptible strains of Escherichia coli or Staphylococcus saprophyticus. Nitrofurantoin is not indicated for the treatment of pyelonephrit...
Nitrofurantoin indications and usage Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2] # Indications and Usage Macrobid is indicated only for the treatment of acute uncomplicated urinary tract infections (acute cystitis) caused by susceptible strains of Esch...
https://www.wikidoc.org/index.php/Nitrofurantoin_indications_and_usage
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Norelgestromin and Ethinyl Estradiol
Norelgestromin and Ethinyl Estradiol # Disclaimer WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educati...
Norelgestromin and Ethinyl Estradiol Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Turky Alkathery, M.D. [2] # Disclaimer WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider...
https://www.wikidoc.org/index.php/Norelgestromin_and_Ethinyl_Estradiol
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Norfloxacin warnings and precautions
Norfloxacin warnings and precautions # Warnings And Precautions ## WARNINGS Tendinopathy and Tendon Rupture: Fluoroquinolones, including NOROXIN, are associated with an increased risk of tendinitis and tendon rupture in all ages. This adverse reaction most frequently involves the Achilles tendon, and rupture of the A...
Norfloxacin warnings and precautions Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2] # Warnings And Precautions ## WARNINGS Tendinopathy and Tendon Rupture: Fluoroquinolones, including NOROXIN, are associated with an increased risk of tendinitis and tendon ruptu...
https://www.wikidoc.org/index.php/Norfloxacin_warnings_and_precautions
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Norovirus diagnostic study of choice
Norovirus diagnostic study of choice # Overview # Diagnostic Study of Choice ## Study of choice is the gold standard test for the diagnosis of . OR The following result of is confirmatory of : OR must be performed when: - The patient presents with , , and . - A is positive for , , and in the patient. OR is the...
Norovirus diagnostic study of choice # Overview # Diagnostic Study of Choice ## Study of choice [Name of the investigation] is the gold standard test for the diagnosis of [disease name]. OR The following result of [gold standard test] is confirmatory of [disease name]: - [Result 1] - [Result 2] OR [Name of the inves...
https://www.wikidoc.org/index.php/Norovirus_diagnostic_study_of_choice
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Nuclear factor Y gene transcriptions
Nuclear factor Y gene transcriptions The protein encoded by this gene is one subunit of a trimeric complex NF-Y, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit NFYA associates with a tight dimer composed of the NFYB and NFYC subunits, re...
Nuclear factor Y gene transcriptions Associate Editor(s)-in-Chief: Henry A. Hoff The protein encoded by this gene is one subunit of a trimeric complex NF-Y, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes.[1] Subunit NFYA associates with a tight...
https://www.wikidoc.org/index.php/Nuclear_factor_Y_gene_transcriptions
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Nucleic acid amplification technique
Nucleic acid amplification technique # Overview Nucleic acid amplification techniques (NAAT) are biochemistry and molecular biology methods that involve the in-vitro synthesis of many copies of DNA or RNA from one original template. # Types of Nucleic Acid Amplification Techniques (NAAT) ## Ligase chain reaction A l...
Nucleic acid amplification technique Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Nucleic acid amplification techniques (NAAT) are biochemistry and molecular biology methods that involve the in-vitro synthesis of many copies of DNA or RNA from one original template.[1] # Types of Nucleic Acid Amplif...
https://www.wikidoc.org/index.php/Nucleic_acid_amplification_technique
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Obtaining venous and arterial access
Obtaining venous and arterial access # Anatomy of the Femoral Triangle The femoral triangle of Scarpa is an anatomical region of the upper inner human thigh. ## Boundaries It is bounded by: - the inguinal ligament superiorly - the sartorius muscle laterally - the adductor longus muscle medially - Its floor is formed ...
Obtaining venous and arterial access Editors-In-Chief: Alexandra Almonacid M.D., Jeffrey J.Popma M.D., C. Michael Gibson, M.S., M.D. # Anatomy of the Femoral Triangle The femoral triangle of Scarpa is an anatomical region of the upper inner human thigh. ## Boundaries It is bounded by: - the inguinal ligament superio...
https://www.wikidoc.org/index.php/Obtaining_Venous_and_Arterial_Access
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Ofloxacin oral (patient information)
Ofloxacin oral (patient information) # Why is this medication prescribed Ofloxacin is an antibiotic used to treat certain infections caused by bacteria, such as pneumonia; bronchitis; venereal disease (VD); and prostate, skin, and urinary tract infections. Antibiotics will not work for colds, flu, or other viral infec...
Ofloxacin oral (patient information) Template:Drug header # Why is this medication prescribed Ofloxacin is an antibiotic used to treat certain infections caused by bacteria, such as pneumonia; bronchitis; venereal disease (VD); and prostate, skin, and urinary tract infections. Antibiotics will not work for colds, flu...
https://www.wikidoc.org/index.php/Ofloxacin_oral
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Ofloxacin otic (patient information)
Ofloxacin otic (patient information) # Why is this medication prescribed Ofloxacin otic is used to treat outer ear infections in adults and children, chronic (long-lasting) middle ear infections in adults and children with a perforated eardrum (a condition where the eardrum has a hole in it), and acute (suddenly occur...
Ofloxacin otic (patient information) Template:Drug header # Why is this medication prescribed Ofloxacin otic is used to treat outer ear infections in adults and children, chronic (long-lasting) middle ear infections in adults and children with a perforated eardrum (a condition where the eardrum has a hole in it), and...
https://www.wikidoc.org/index.php/Ofloxacin_otic
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Ondine's curse (patient information)
Ondine's curse (patient information) For the WikiDoc page for this topic, click here Synonyms and Keywords: Congenital central hypoventilation syndrome; CCHS; Primary alveolar hypoventilation # Overview Primary alveolar hypoventilation is a rare disorder of unknown cause in which a person does not take enough breaths ...
Ondine's curse (patient information) For the WikiDoc page for this topic, click here Editor-in-Chief: C. Michael Gibson, M.S.,M.D. [1] Phone:617-632-7753; Associate Editor-In-Chief: Lakshmi Gopalakrishnan, M.B.B.S. Synonyms and Keywords: Congenital central hypoventilation syndrome; CCHS; Primary alveolar hypoventilati...
https://www.wikidoc.org/index.php/Ondine%27s_curse_(patient_information)
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wikidoc
Oseltamivir warnings and precautions
Oseltamivir warnings and precautions # Warnings And Precautions ## Serious Skin/Hypersensitivity Reactions Cases of anaphylaxis and serious skin reactions including toxic epidermal necrolysis, Stevens-Johnson Syndrome, and erythema multiforme have been reported in postmarketing experience with TAMIFLU. TAMIFLU should...
Oseltamivir warnings and precautions Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2] # Warnings And Precautions ## Serious Skin/Hypersensitivity Reactions Cases of anaphylaxis and serious skin reactions including toxic epidermal necrolysis, Stevens-Johnson Syndr...
https://www.wikidoc.org/index.php/Oseltamivir_warnings_and_precautions
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Posterior inferior cerebellar artery
Posterior inferior cerebellar artery # Overview The posterior inferior cerebellar artery (PICA), the largest branch of the vertebral, is one of the three main arterial blood supplies for the cerebellum. # Course It winds backward around the upper part of the medulla oblongata, passing between the origins of the vagu...
Posterior inferior cerebellar artery Template:Infobox Artery Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview The posterior inferior cerebellar artery (PICA), the largest branch of the vertebral, is one of the three main arterial blood supplies for the cerebellum. # Course It winds backward around the ...
https://www.wikidoc.org/index.php/PICA
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Plaque reduction neutralization test
Plaque reduction neutralization test # Overview The Plaque reduction neutralization test is used to quantify the titre of neutralising antibody for a virus. The serum sample or solution of antibody to be tested is diluted and mixed with a viral suspension. This is incubated to allow the antibody to react with the viru...
Plaque reduction neutralization test Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview The Plaque reduction neutralization test is used to quantify the titre of neutralising antibody for a virus. The serum sample or solution of antibody to be tested is diluted and mixed with a viral suspension. This is in...
https://www.wikidoc.org/index.php/PRNT
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Palivizumab warnings and precautions
Palivizumab warnings and precautions # Warnings And Precautions ## Hypersensitivity Reactions Cases of anaphylaxis and anaphylactic shock, including fatal cases, have been reported following initial exposure or re-exposure to Synagis. Other acute hypersensitivity reactions, which may be severe, have also been reporte...
Palivizumab warnings and precautions Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2] # Warnings And Precautions ## Hypersensitivity Reactions Cases of anaphylaxis and anaphylactic shock, including fatal cases, have been reported following initial exposure or re-...
https://www.wikidoc.org/index.php/Palivizumab_warnings_and_precautions
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Pancytopenia resident survival guide
Pancytopenia resident survival guide Synonyms and keywords: Approach to pancytopenia, Pancytopenia management, Pancytopenia work-up # Overview Pancytopenia is described as a decrease in the 3 cell lines which are red blood cells, white blood cells, and platelets. Clinically, pancytopenia is defined as hemoglobin< 9gm,...
Pancytopenia resident survival guide Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sanjana Nethagani, M.B.B.S.[2] Synonyms and keywords: Approach to pancytopenia, Pancytopenia management, Pancytopenia work-up # Overview Pancytopenia is described as a decrease in the 3 cell lines wh...
https://www.wikidoc.org/index.php/Pancytopenia_resident_survival_guide
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Panic disorder (patient information)
Panic disorder (patient information) For the WikiDoc page for this topic, click here # Overview Panic disorder is a type of anxiety disorder in which you have repeated attacks of intense fear that something bad will occur when not expected. # What are the symptoms of Panic disorder? - A panic attack begins suddenly, ...
Panic disorder (patient information) For the WikiDoc page for this topic, click here Editor-in-Chief: C. Michael Gibson, M.S.,M.D. [1] Phone:617-632-7753; Associate Editor-In-Chief: Lakshmi Gopalakrishnan, M.B.B.S. # Overview Panic disorder is a type of anxiety disorder in which you have repeated attacks of intense f...
https://www.wikidoc.org/index.php/Panic_disorder_(patient_information)
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Paroxysmal AV Block echocardiography
Paroxysmal AV Block echocardiography # Overview Echocardiography has a highler yield where diagnosing syncope and presyncope is concerned, in patients with structural heart disease. # Echocardiography ## 2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction D...
Paroxysmal AV Block echocardiography Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Akash Daswaney, M.B.B.S[2] # Overview Echocardiography has a highler yield where diagnosing syncope and presyncope is concerned, in patients with structural heart disease. # Echocardiography ## 20...
https://www.wikidoc.org/index.php/Paroxysmal_AV_Block_echocardiography
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Patau syndrome (patient information)
Patau syndrome (patient information) For the WikiDoc page for this topic, click here # Overview Trisomy 13 (also called Patau syndrome) is a genetic disorder in which a person has three copies of genetic material from chromosome 13, instead of the usual two copies. Rarely, the extra material may be attached to another...
Patau syndrome (patient information) For the WikiDoc page for this topic, click here Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Assistant Editor-in-Chief: Ethan Leeman # Overview Trisomy 13 (also called Patau syndrome) is a genetic disorder in which a person has three copies of genetic material from chromoso...
https://www.wikidoc.org/index.php/Patau_syndrome_(patient_information)
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Pathophysiology compartment syndrome
Pathophysiology compartment syndrome # Overview Any condition that results in an increase in compartment contents or reduction in a compartment’s volume could lead to the development of an acute compartment syndrome. When pressure is elevated capillary blood flow is compromised. Edema of the soft tissue within the com...
Pathophysiology compartment syndrome Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohammadmain Rezazadehsaatlou[2] ; # Overview Any condition that results in an increase in compartment contents or reduction in a compartment’s volume could lead to the development of an acute compar...
https://www.wikidoc.org/index.php/Pathophysiology_compartment_syndrome
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Pelvic inflammatory disease
Pelvic inflammatory disease overview # Overview Pelvic inflammatory disease is a generic term for the infection of the female uterus, fallopian tubes, and/or ovaries as it progresses to scar formation with adhesions to nearby tissues and organs. This may lead to tissue necrosis (with or without abscess formation). Pu...
Pelvic inflammatory disease overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Seyedmahdi Pahlavani, M.D. [2] # Overview Pelvic inflammatory disease is a generic term for the infection of the female uterus, fallopian tubes, and/or ovaries as it progresses to scar formation with...
https://www.wikidoc.org/index.php/Pelvic_inflammatory_disease_overview
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Penicillin G benzathine how supplied
Penicillin G benzathine how supplied # How Supplied Bicillin L-A (penicillin G benzathine injectable suspension) is supplied in packages of 10 disposable syringes as follows: 1 mL size, containing 600,000 units per syringe, (21 gauge, thin-wall 1 inch needle for pediatric use), NDC 60793-700-10. 2 mL size, containing...
Penicillin G benzathine how supplied Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2] # How Supplied Bicillin L-A (penicillin G benzathine injectable suspension) is supplied in packages of 10 disposable syringes as follows: 1 mL size, containing 600,000 un...
https://www.wikidoc.org/index.php/Penicillin_G_benzathine_how_supplied
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Penicillin G benzathine microbiology
Penicillin G benzathine microbiology # Microbiology ### Mechanism of Action Penicillin G exerts a bactericidal action against penicillin-susceptible microorganisms during the stage of active multiplication. It acts through the inhibition of biosynthesis of cell-wall peptidoglycan, rendering the cell wall osmotically...
Penicillin G benzathine microbiology Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2] # Microbiology ### Mechanism of Action Penicillin G exerts a bactericidal action against penicillin-susceptible microorganisms during the stage of active multiplication. ...
https://www.wikidoc.org/index.php/Penicillin_G_benzathine_microbiology
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Pentoxifylline (patient information)
Pentoxifylline (patient information) # Why this medication is prescribed Pentoxifylline is used to improve blood flow in patients with circulation problems to reduce aching, cramping, and tiredness in the hands and feet. It works by decreasing the thickness (viscosity) of blood. This change allows your blood to flow m...
Pentoxifylline (patient information) Template:Drug header # Why this medication is prescribed Pentoxifylline is used to improve blood flow in patients with circulation problems to reduce aching, cramping, and tiredness in the hands and feet. It works by decreasing the thickness (viscosity) of blood. This change allow...
https://www.wikidoc.org/index.php/Pentoxifylline_(patient_information)
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wikidoc
Peripheral arterial disease
Peripheral arterial disease overview # Overview The term peripheral arterial disease refers to a group of disorders characterized by progressive stenosis and altered structure and function of non coronary arteries that supply the brain, visceral organs and limbs. Peripheral arterial disease (PAD) are most commonly of ...
Peripheral arterial disease overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-In-Chief: Maheep Singh Sangha, M.B.B.S.; Cafer Zorkun, M.D., Ph.D. [2]; Rim Halaby # Overview The term peripheral arterial disease refers to a group of disorders characterized by progressive stenosis and altere...
https://www.wikidoc.org/index.php/Peripheral_arterial_disease_overview
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wikidoc
Permanent neonatal diabetes mellitus
Permanent neonatal diabetes mellitus A newly identified and potentially treatable form of monogenic diabetes is the neonatal diabetes caused by activating mutations of the KCNJ11 gene, which codes for the Kir6.2 subunit of the beta cell KATP channel. This disease is considered to be a type of maturity onset diabetes of...
Permanent neonatal diabetes mellitus Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] A newly identified and potentially treatable form of monogenic diabetes is the neonatal diabetes caused by activating mutations of the KCNJ11 gene, which codes for the Kir6.2 subunit of the beta cell KATP channel.[1][2] This diseas...
https://www.wikidoc.org/index.php/Permanent_neonatal_diabetes_mellitus
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wikidoc
Phenytoin oral (patient information)
Phenytoin oral (patient information) # Why is this medication prescribed Phenytoin is used to treat various types of convulsions and seizures. Phenytoin acts on the brain and nervous system in the treatment of epilepsy. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more info...
Phenytoin oral (patient information) Template:Drug header # Why is this medication prescribed Phenytoin is used to treat various types of convulsions and seizures. Phenytoin acts on the brain and nervous system in the treatment of epilepsy. This medication is sometimes prescribed for other uses; ask your doctor or ph...
https://www.wikidoc.org/index.php/Phenytoin_oral
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wikidoc
Phosphatidylcholine transfer protein
Phosphatidylcholine transfer protein Phosphatidylcholine transfer protein (PCTP) also known as StAR-related lipid transfer domain protein 2 (STARD2) is a specific intracellular phospholipid binding protein that can transfer phosphatidylcholine between different membranes in the cytosol. In humans, phosphatidylcholine t...
Phosphatidylcholine transfer protein Phosphatidylcholine transfer protein (PCTP) also known as StAR-related lipid transfer domain protein 2 (STARD2) is a specific intracellular phospholipid binding protein that can transfer phosphatidylcholine between different membranes in the cytosol.[1][2] In humans, phosphatidylch...
https://www.wikidoc.org/index.php/Phosphatidylcholine_transfer_protein
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wikidoc
Pick's disease (patient information)
Pick's disease (patient information) For the WikiDoc page for this topic, click here Synonyms and Keywords: Semantic dementia; Dementia - semantic; Frontotemporal dementia; Arnold Pick's disease # Overview Pick's disease is a rare and permanent form of dementia that is similar to Alzheimer's disease, except that it te...
Pick's disease (patient information) For the WikiDoc page for this topic, click here Editor-in-Chief: C. Michael Gibson, M.S.,M.D. [1] Phone:617-632-7753; Associate Editor-In-Chief: Lakshmi Gopalakrishnan, M.B.B.S. Synonyms and Keywords: Semantic dementia; Dementia - semantic; Frontotemporal dementia; Arnold Pick's di...
https://www.wikidoc.org/index.php/Pick%27s_disease_(patient_information)
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wikidoc
Pineocytoma other diagnostic studies
Pineocytoma other diagnostic studies # Overview There are no other diagnostic studies associated with . OR may be helpful in the diagnosis of . Findings suggestive of/diagnostic of include , , and . OR Other diagnostic studies for include , which demonstrates , , and , and , which demonstrates , , and . # Other Di...
Pineocytoma other diagnostic studies Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2] Homa Najafi, M.D.[3] # Overview There are no other diagnostic studies associated with [disease name]. OR [Diagnostic study] may be helpful in the diagnosis of [disease name]. Fi...
https://www.wikidoc.org/index.php/Pineocytoma_other_diagnostic_studies
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wikidoc
Solitary fibrous tumor of the pleura
Solitary fibrous tumor of the pleura # Overview Solitary fibrous tumor of the pleura is mostly asymptomatic. The lesion is usually discovered incidentally on chest radiographs. The tumor may become large, occupying much of the hemithorax. When present, symptoms are usually related to the local mass effect of large les...
Solitary fibrous tumor of the pleura Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Solitary fibrous tumor of the pleura is mostly asymptomatic. The lesion is usually discovered incidentally on chest radiographs. The tumor may become large, occupying much of the hemithorax. When present, symptoms are u...
https://www.wikidoc.org/index.php/Pleural_fibroma
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Polyhydramnios (patient information)
Polyhydramnios (patient information) For the WikiDoc page for this topic, click here # Overview Polyhydramnios is the presence of excessive amniotic fluid surrounding the unborn infant. # Considerations - Amniotic fluid is a clear, slightly yellowish liquid that surrounds the unborn baby (fetus) during pregnancy. It ...
Polyhydramnios (patient information) For the WikiDoc page for this topic, click here Editor-in-Chief: C. Michael Gibson, M.S.,M.D. [1] Phone:617-632-7753; Associate Editor(s)-In-Chief: Lakshmi Gopalakrishnan, M.B.B.S. # Overview Polyhydramnios is the presence of excessive amniotic fluid surrounding the unborn infant....
https://www.wikidoc.org/index.php/Polyhydramnios_(patient_information)
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wikidoc
Popliteal artery entrapment syndrome
Popliteal artery entrapment syndrome # Overview The popliteal artery entrapment syndrome is a rather uncommon pathology, which results into claudication and chronic leg ischemia. The popliteal artery may be compressed behind the knee, due to congenital deformity of the muscles or tendon insertions of the popliteal spa...
Popliteal artery entrapment syndrome Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview The popliteal artery entrapment syndrome is a rather uncommon pathology, which results into claudication and chronic leg ischemia. The popliteal artery may be compressed behind the knee, due to congenital deformity of t...
https://www.wikidoc.org/index.php/Popliteal_artery_entrapment_syndrome
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wikidoc
Post-micturition convulsion syndrome
Post-micturition convulsion syndrome Steven C. Campbell, M.D., Ph.D. Please Join in Editing This Page and Apply to be an Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us to indicate yo...
Post-micturition convulsion syndrome Template:Search infobox Steven C. Campbell, M.D., Ph.D. Please Join in Editing This Page and Apply to be an Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Pleas...
https://www.wikidoc.org/index.php/Post-micturition_convulsion_syndrome
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wikidoc
Preeclampsia resident survival guide
Preeclampsia resident survival guide Synonyms and keywords: Approach to preeclampsia , Approach to gestational hypertension with proteinuria # Overview Preeclampsia is primarily defined as gestational hypertension with proteinuria 300 mg or more over a 24-hour period. The pathophysiologic abnormalities of preeclampsia...
Preeclampsia resident survival guide Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rinky Agnes Botleroo, M.B.B.S. Synonyms and keywords: Approach to preeclampsia , Approach to gestational hypertension with proteinuria # Overview Preeclampsia is primarily defined as gestational hyp...
https://www.wikidoc.org/index.php/Preeclampsia_resident_survival_guide
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wikidoc
Pressure ulcer (patient information)
Pressure ulcer (patient information) For the WikiDoc page for this topic, click here # Overview A pressure ulcer is an area of skin that breaks down when constant pressure is placed against the skin. # What are the symptoms of a Pressure ulcer? A pressure ulcer starts as reddened skin that gets worse over time. It fo...
Pressure ulcer (patient information) For the WikiDoc page for this topic, click here Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview A pressure ulcer is an area of skin that breaks down when constant pressure is placed against the skin. # What are the symptoms of a Pressure ulcer? A pressure ulcer star...
https://www.wikidoc.org/index.php/Pressure_ulcer_(patient_information)
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Prolactin-releasing peptide receptor
Prolactin-releasing peptide receptor The prolactin-releasing peptide receptor (PrRPR) also known as G-protein coupled receptor 10 (GPR10) is a protein that in humans is encoded by the PRLHR gene. PrRPR is a G-protein coupled receptor that binds the prolactin-releasing peptide (PRLH). # Function PrRPR is a 7-transmembr...
Prolactin-releasing peptide receptor The prolactin-releasing peptide receptor (PrRPR) also known as G-protein coupled receptor 10 (GPR10) is a protein that in humans is encoded by the PRLHR gene. PrRPR is a G-protein coupled receptor[1] that binds the prolactin-releasing peptide (PRLH).[2] # Function PrRPR is a 7-tra...
https://www.wikidoc.org/index.php/Prolactin-releasing_peptide_receptor
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wikidoc
Protein Z-related protease inhibitor
Protein Z-related protease inhibitor Protein Z-dependent protease inhibitor is a protein circulating in the blood which inhibits factors Xa and XIa of the coagulation cascade. It is a member of the class of the serine protease inhibitors (serpins). Its name implies that it requires protein Z, another circulating protei...
Protein Z-related protease inhibitor Protein Z-dependent protease inhibitor is a protein circulating in the blood which inhibits factors Xa and XIa of the coagulation cascade. It is a member of the class of the serine protease inhibitors (serpins). Its name implies that it requires protein Z, another circulating prote...
https://www.wikidoc.org/index.php/Protein_Z-dependent_protease_inhibitor
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wikidoc
Protein arginine methyltransferase 5
Protein arginine methyltransferase 5 Protein arginine N-methyltransferase 5 is an enzyme that in humans is encoded by the PRMT5 gene. PRMT5 symmetrically dimethylates H2AR3, H4R3, H3R2, and H3R8 in vivo, all of which are linked to a range of transcriptional regulatory events (Cell. Mol. Life Sci. (2015) 72:2041–2059 D...
Protein arginine methyltransferase 5 Protein arginine N-methyltransferase 5 is an enzyme that in humans is encoded by the PRMT5 gene.[1][2] PRMT5 symmetrically dimethylates H2AR3, H4R3, H3R2, and H3R8 in vivo, all of which are linked to a range of transcriptional regulatory events (Cell. Mol. Life Sci. (2015) 72:2041...
https://www.wikidoc.org/index.php/Protein_arginine_methyltransferase_5
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wikidoc
Protein energy malnutrition
Protein energy malnutrition overview # Overview Protein energy malnutrition is defined by measurements that fall below 2 standard deviations under the normal weight for age (underweight), height for age (stunting) and weight for height (wasting). Protein energy malnutrition is a nutritional deficiency resulting from e...
Protein energy malnutrition overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Omodamola Aje B.Sc, M.D. [2] # Overview Protein energy malnutrition is defined by measurements that fall below 2 standard deviations under the normal weight for age (underweight), height for age (st...
https://www.wikidoc.org/index.php/Protein_energy_malnutrition_overview
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wikidoc
Pulmonary arteriovenous malformation
Pulmonary arteriovenous malformation # Overview A pulmonary arteriovenous malformation (PAVM) is an abnormal connection between a branch of a pulmonary artery and a pulmonary vein through a thin-walled aneurysmal sac. PAVMs are most commonly congenital in nature and have a strong relationship with the syndrome of her...
Pulmonary arteriovenous malformation Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview A pulmonary arteriovenous malformation (PAVM) is an abnormal connection between a branch of a pulmonary artery and a pulmonary vein through a thin-walled aneurysmal sac. PAVMs are most commonly congenital in nature and ...
https://www.wikidoc.org/index.php/Pulmonary_arteriovenous_malformation
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wikidoc
Quinidine Oral (patient information)
Quinidine Oral (patient information) # IMPORTANT WARNING Studies have shown that some antiarrhythmic drugs may increase the risk of death, especially if you have had a previous heart attack. This information also may apply to quinidine. Quinidine usually is used only to treat life-threatening arrhythmias. # Why this ...
Quinidine Oral (patient information) Template:Drug header # IMPORTANT WARNING Studies have shown that some antiarrhythmic drugs may increase the risk of death, especially if you have had a previous heart attack. This information also may apply to quinidine. Quinidine usually is used only to treat life-threatening arr...
https://www.wikidoc.org/index.php/Quinidine_Oral
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wikidoc
Radial catheterization complications
Radial catheterization complications # Overview Like any other arterial puncture in any part of the body, complications are not uncommon, including radial artery spasms and occlusion, bleeding, radiation exposure, e.t.c. However, these complications can be minimized by the use of appropriate medications, radiation pr...
Radial catheterization complications Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Varun Kumar, M.B.B.S.; Lakshmi Gopalakrishnan, M.B.B.S.; Ayokunle Olubaniyi, M.B,B.S [2] # Overview Like any other arterial puncture in any part of the body, complications are not uncommon, including ra...
https://www.wikidoc.org/index.php/Radial_catheterization_complications
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wikidoc
Raltegravir warnings and precautions
Raltegravir warnings and precautions # Warnings And Precautions ## Severe Skin and Hypersensitivity Reactions Severe, potentially life-threatening, and fatal skin reactions have been reported. These include cases of Stevens-Johnson syndrome and toxic epidermal necrolysis. Hypersensitivity reactions have also been rep...
Raltegravir warnings and precautions Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chetan Lokhande, M.B.B.S [2] # Warnings And Precautions ## Severe Skin and Hypersensitivity Reactions Severe, potentially life-threatening, and fatal skin reactions have been reported. These includ...
https://www.wikidoc.org/index.php/Raltegravir_warnings_and_precautions
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wikidoc
Rapid eye movement behavior disorder
Rapid eye movement behavior disorder # Overview Rapid eye movement behaviour disorder, or RBD was first described in 1986 as a parasomnia involving dissociation of the characteristic stages of sleep. The major and arguably only abnormal feature of RBD is loss of muscle atonia (paralysis) during otherwise intact REM sl...
Rapid eye movement behavior disorder Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Rapid eye movement behaviour disorder, or RBD was first described in 1986 as a parasomnia involving dissociation of the characteristic stages of sleep. The major and arguably only abnormal feature of RBD is loss of musc...
https://www.wikidoc.org/index.php/Rapid_eye_movement_behavior_disorder
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wikidoc
Retapamulin warnings and precautions
Retapamulin warnings and precautions # Warnings and Precautions ### Local Irritation In the event of sensitization or severe local irritation from ALTABAX, usage should be discontinued, the ointment wiped off, and appropriate alternative therapy for the infection instituted . ### Not for Systemic or Mucosal Use ALTA...
Retapamulin warnings and precautions Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Warnings and Precautions ### Local Irritation In the event of sensitization or severe local irritation from ALTABAX, usage should be discontinued, the ointment wiped off, and appropriate alternative therapy for the infection in...
https://www.wikidoc.org/index.php/Retapamulin_warnings_and_precautions
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wikidoc
Reverse Bennett fracture-dislocation
Reverse Bennett fracture-dislocation # Overview The Reverse Bennett fracture-dislocation is a fracture of the neck of the 5th metacarpal bone and known as the most common metacarpal fracture. The early diagnosis and treatment are imperative to prevent loss of function of this highly mobile human joint system. This fra...
Reverse Bennett fracture-dislocation Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohammadmain Rezazadehsaatlou[2]. # Overview The Reverse Bennett fracture-dislocation is a fracture of the neck of the 5th metacarpal bone and known as the most common metacarpal fracture. The early ...
https://www.wikidoc.org/index.php/Reverse_Bennett_fracture-dislocation
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wikidoc
Rheumatism by Dr. Lance Christiansen
Rheumatism by Dr. Lance Christiansen Undergoing edit with the addition of references through March 2013. (LWC) # Overview Rheumatism is usually considered to be an archaic term in medical science for it is not listed as a subject within the index of most modern, medical texts. For instance, it is not listed in the ind...
Rheumatism by Dr. Lance Christiansen Editor-in-Chief: Lance Christiansen, D.O. Undergoing edit with the addition of references through March 2013. (LWC) # Overview Rheumatism is usually considered to be an archaic term in medical science for it is not listed as a subject within the index of most modern, medical texts...
https://www.wikidoc.org/index.php/Rheumatism
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wikidoc
Rifampin isoniazid adverse reactions
Rifampin isoniazid adverse reactions # ADVERSE REACTIONS ## Rifampin ### Nervous system reactions Headache, drowsiness, fatigue, ataxia, dizziness, inability to concentrate, mental confusion, visual disturbances, muscular weakness, pain in extremities, and generalized numbness ### Gastrointestinal disturbances In s...
Rifampin isoniazid adverse reactions Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chetan Lokhande, M.B.B.S [2] # ADVERSE REACTIONS ## Rifampin ### Nervous system reactions Headache, drowsiness, fatigue, ataxia, dizziness, inability to concentrate, mental confusion, visual distu...
https://www.wikidoc.org/index.php/Rifampin_isoniazid_adverse_reactions
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wikidoc
Rifapentine warnings and precautions
Rifapentine warnings and precautions # Warnings And Precautions ## HIV Seropositive Patients Rifapentine should not be used as a once weekly Continuation Phase regimen in combination with isoniazid in HIV seropositive patients with pulmonary tuberculosis because of a higher rate of failure and/or relapse documented w...
Rifapentine warnings and precautions Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chetan Lokhande, M.B.B.S [2] # Warnings And Precautions ## HIV Seropositive Patients Rifapentine should not be used as a once weekly Continuation Phase regimen in combination with isoniazid in HIV ...
https://www.wikidoc.org/index.php/Rifapentine_warnings_and_precautions
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wikidoc
Rilpivirine warnings and precautions
Rilpivirine warnings and precautions # Warnings And Precautions ## Drug Interactions Caution should be given to prescribing EDURANT with drugs that may reduce the exposure of rilpivirine . In healthy subjects, supratherapeutic doses of rilpivirine (75 mg once daily and 300 mg once daily) have been shown to prolong th...
Rilpivirine warnings and precautions Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chetan Lokhande, M.B.B.S [2] # Warnings And Precautions ## Drug Interactions Caution should be given to prescribing EDURANT with drugs that may reduce the exposure of rilpivirine [see Contraindicat...
https://www.wikidoc.org/index.php/Rilpivirine_warnings_and_precautions
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wikidoc
Rimantadine warnings and precautions
Rimantadine warnings and precautions # Warnings And Precautions GENERAL: An increased incidence of seizures has been reported in patients with a history of epilepsy who received the related drug amantadine In clinical trials of Flumadine, the occurrence of seizure-like activity was observed in a small number of patien...
Rimantadine warnings and precautions Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Warnings And Precautions GENERAL: An increased incidence of seizures has been reported in patients with a history of epilepsy who received the related drug amantadine In clinical trials of Flumadine, the occurrence of seizure-li...
https://www.wikidoc.org/index.php/Rimantadine_warnings_and_precautions
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wikidoc
Rizatriptan warnings and precautions
Rizatriptan warnings and precautions # Warnings and Precautions ### 5.1 Myocardial Ischemia, Myocardial Infarction, and Prinzmetal's Angina MAXALT should not be given to patients with ischemic or vasospastic coronary artery disease. There have been rare reports of serious cardiac adverse reactions, including acute my...
Rizatriptan warnings and precautions Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Warnings and Precautions ### 5.1 Myocardial Ischemia, Myocardial Infarction, and Prinzmetal's Angina MAXALT should not be given to patients with ischemic or vasospastic coronary artery disease. There have been rare reports of s...
https://www.wikidoc.org/index.php/Rizatriptan_warnings_and_precautions
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wikidoc
Sinoatrial nodal reentry tachycardia
Sinoatrial nodal reentry tachycardia Synonyms and keywords: SA nodal reentrant tachycardia; SANRT; sinus node reentrant tachycardia # Overview Sinoatrial nodal reentry tachycardia (SANRT) is caused by a reentry circuit localized to the SA node. # Causes ## Life Threatening Causes Life-threatening causes include cond...
Sinoatrial nodal reentry tachycardia Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Synonyms and keywords: SA nodal reentrant tachycardia; SANRT; sinus node reentrant tachycardia # Overview Sinoatrial nodal reentry tachycardia (SANRT) is caused by a reentry circuit localized to the SA node. # Causes ## Life Thr...
https://www.wikidoc.org/index.php/SANRT
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wikidoc
Salicylic acid (patient information)
Salicylic acid (patient information) # Why is this medication prescribed? - Topical salicylic acid is used to help clear and prevent pimples and skin blemishes in people who have acne. Topical salicylic acid is also used to treat skin conditions that involve scaling or overgrowth of skin cells such as psoriasis (a ski...
Salicylic acid (patient information) Template:Drug header # Why is this medication prescribed? - Topical salicylic acid is used to help clear and prevent pimples and skin blemishes in people who have acne. Topical salicylic acid is also used to treat skin conditions that involve scaling or overgrowth of skin cells su...
https://www.wikidoc.org/index.php/Salicylic_acid_(patient_information)
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wikidoc
Sandbox:Otitis media medical therapy
Sandbox:Otitis media medical therapy # Overview The mainstay of therapy for acute otitis media (AOM) is antimicrobial therapy. High-dose Amoxicillin is the drug of choice for initial antibiotic therapy; high-dose Amoxicillin-Clavulanate or intramuscular Ceftriaxone should be reserved for patients who fail to respond t...
Sandbox:Otitis media medical therapy Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Maliha Shakil, M.D. [2]; Shanshan Cen, M.D. [3]; Mohamed Moubarak, M.D. [4]; Luke Rusowicz-Orazem, B.S. # Overview The mainstay of therapy for acute otitis media (AOM) is antimicrobial therapy. High-...
https://www.wikidoc.org/index.php/Sandbox:Otitis_media_medical_therapy
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wikidoc
Sandbox:Pertussis primary prevention
Sandbox:Pertussis primary prevention # Overview Childhood vaccination is highly effective in preventing pertussis. Routine childhood vaccination in the United States is performed with the DTaP vaccine (acellular pertussis vaccine combined with tetanus and diphtheria toxoids). # Vaccines Use of Acellular Pertussis Vac...
Sandbox:Pertussis primary prevention Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Childhood vaccination is highly effective in preventing pertussis. Routine childhood vaccination in the United States is performed with the DTaP vaccine (acellular pertussis vaccine combined with tetanus and diphtheria ...
https://www.wikidoc.org/index.php/Sandbox:Pertussis_primary_prevention