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Repair of medial collateral ligament injury during total knee arthoplasty
PJI DX Updated Search
Intraoperative midsubstance lacerations of the medial collateral ligament (MCL) must be addressed during surgery, and failure to obtain coronal plane stability could affect patient outcomes and satisfaction. This article reports our results of a series of patients who sustained an intraoperative MCL injury during a pri...
0
MRSA colonisation in patients with proximal femur fractures in a German trauma centre: Incidence, infection rates and outcomes
PJI DX Updated Search
Purpose: The aim of this study was to assess the incidence of methicillin-resistant Staphylococcus aureus (MRSA) colonisation in patients admitted into a level 1 German trauma centre with proximal femur fractures, to correlate this incidence with defined risk factors for MRSA colonisation and to determine its influence...
1
Prepectoral Direct-to-Implant Breast Reconstruction: Safety Outcome Endpoints and Delineation of Risk Factors
Acellular Dermal Matrix
BACKGROUND: Continued evolution of implant-based breast reconstruction involves immediate placement of the implant above the pectoralis muscle. The shift to prepectoral breast reconstruction is driven by goals of decreasing morbidity such as breast animation deformity, range-of-motion problems, and pain, and is made po...
0
Efficacy of nonsteroidal anti-inflammatory drugs in the management of postoperative pain
AAHKS (4) Acetaminophen
Nonsteroidal anti-inflammatory drugs (NSAIDs) are very effective for the management of acute postoperative pain. These agents can be used in combination with opioid analgesics and local anaesthetics for the relief of severe postoperative pain, when the combination results in reduced narcotic requirements and improved a...
0
Bone shape mediates the relationship between sex and incident knee osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
Background: Knee bone shape differs between men and women and the incidence of knee osteoarthritis (OA) is higher in women than in men. Therefore, the purpose of the present study was to determine whether the observed difference in the incidence of knee radiographic OA (ROA) between men and women is mediated by bone sh...
0
Emergency Orthogeriatrics: Concepts and Therapeutic Considerations for the Geriatric Patient
Hip Fx in the Elderly 2019
Appropriate recognition of the physiologic, psychological, and clinical differences among geriatric patients, with respect to orthopedic injury and disease, is paramount for all emergency medicine providers to ensure they are providing high-value care for this vulnerable population.
0
"Slow walk" mimetic tensile loading maintains human meniscus tissue resident progenitor cells homeostasis in photocrosslinked gelatin hydrogel
AMP (Acute Meniscal Pathology)
Meniscus, the cushion in knee joint, is a load-bearing tissue that transfers mechanical forces to extracellular matrix (ECM) and tissue resident cells. The mechanoresponse of human tissue resident stem/progenitor cells in meniscus (hMeSPCs) is significant to tissue homeostasis and regeneration but is not well understoo...
0
Plate fixation of femoral nonunions over an intramedullary nail with autogenous bone grafting
Management of Hip Fractures in the Elderly
Objective: To describe a novel approach for the treatment of nonunions of diaphyseal femur fractures. Design: Retrospective review. Setting: University hospital. Patients: Seven patients (six men, one woman, average age 42.5 years) with diaphyseal femoral fracture nonunions treated between November 2006 and November 20...
0
Limb salvage in the upper limb: A review
MSTS 2022 - Metastatic Disease of the Humerus
Limb salvage has replaced amputation as the mainstay of treatment for upper limb primary sarcomas, metastases, complex limb reconstruction in arthroplasty, and as salvage after trauma. There is currently no consensus as to the optimal reconstructive technique. Regardless of the technique used, however, there may be fun...
0
Multifocal motor neuropathy in a patient with genetically confirmed familial CMT1A
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Background: Immune mediated neuropathies such as CIDP and paraproteinemic neuropathy may occur in patients with inherited neuropathy while little is known on the association with multifocal motor neuropathy (MMN). Case report: A 58 years-old man with familial history of genetically confirmed Charcot-Marie-Tooth type 1A...
0
Sonographic assessment of carpal tunnel syndrome in rheumatoid arthritis: prevalence and correlation with disease activity
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Carpal tunnel syndrome (CTS) is one of the most frequent extra-articular manifestations of rheumatoid arthritis (RA). High frequency ultrasonography (US) is a sensitive and specific method in diagnosis of CTS. This study is aimed to: firstly assess diameter frequency of CTS in RA with US and compare with a control grou...
0
Disease-modifying drugs for knee osteoarthritis: can they be cost-effective?
AAHKS (2) Corticosteroids
OBJECTIVE: Disease-modifying osteoarthritis drugs (DMOADs) are under development. Our goal was to determine efficacy, toxicity, and cost thresholds under which DMOADs would be a cost-effective knee OA treatment. DESIGN: We used the Osteoarthritis Policy Model, a validated computer simulation of knee OA, to compare guid...
0
Amputation Stump Revision Using a Free Sural Neurocutaneous Perforator Flap
DoD LSA (Limb Salvage vs Amputation)
BACKGROUND: The development of microsurgery and the concept of the surgical flap have enabled orthopedic surgeons to deal with various soft tissue defects and compositions during limb salvage procedures. However, severely damaged bony structures with accompanying soft tissue deficiencies often result in amputation. Whe...
0
Cathepsin B, L, and D activities in colorectal carcinomas: relationship with clinico-pathological parameters
MSTS 2018 - Femur Mets and MM
Cathepsins, which are secreted by tumour and/or stromal cells, are thought to be involved in the degradative processes of tumour invasion and metastasis. The purpose of our study was to compare the cytosolic content of cathepsin B, L, and D in a series of matched malignant and adjacent normal colorectal tissues. Furthe...
0
Clinical, microbiologic, and biochemical effects of subgingival administration of a Xanthan-based chlorhexidine gel in the treatment of periodontitis: a randomized multicenter trial
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
BACKGROUND: The use of locally delivered antibacterials containing chlorhexidine (CHX) was proposed to improve the effectiveness of non-surgical periodontal treatment. The present multicenter randomized study investigated the effects of a xanthan-based chlorhexidine (Xan-CHX) gel used as an adjunct to scaling and root ...
0
Different patterns of meniscal tears in acute anterior cruciate ligament (ACL) ruptures and in chronic ACL-deficient knees. Classification, staging and timing of treatment
AMP (Acute Meniscal Pathology)
Through the retrospective study of 1103 reconstructions of the anterior cruciate ligament (ACL) performed between 1984 and 1993, we try to outline the natural history of meniscal tears in acute lesions and in chronic insufficiency of the ACL. According to a more accurate evaluation of the clinical evolution, ACL-defici...
0
The place of surgery in rheumatoid arthritis
Surgical Management of Osteoarthritis of the Knee CPG
The medical and surgical management of patients with rheumatoid disease has improved over recent years. Despite the improvements, much disability and pain arise from the condition. The major surgical advances in recent years have been in the field of joint replacement, and these advances are continuing. Joint replaceme...
1
Patient-reported outcomes after acute carpal tunnel release in patients with distal radius open reduction internal fixation
Distal Radius Fractures
BACKGROUND: Acute carpal tunnel syndrome (CTS) is a complication that can develop after distal radius fractures. Our hypothesis tested whether patient-reported outcomes after acute carpal tunnel release (CTR) performed in combination with distal radius fracture open reduction internal fixation (ORIF) are worse than pat...
0
The value of clinical examination in the diagnosis of carpal tunnel syndrome
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Carpal tunnel syndrome is the most common neuropathy of the peripheral nerves. In diagnosing carpal tunnel syndrome, the case history and physical examination are of primary importance. The goal of our research was to examine the dependencies between particular clinical parameters in the diagnosis of carpal tunnel synd...
0
Surgical Treatment of Adolescent Acetabular Dysplasia With a Periacetabular Osteotomy: Does Obesity Increase the Risk of Complications?
Developmental Dysplasia of the Hip 2020 Review
BACKGROUND: The Bernese periacetabular osteotomy (PAO) is frequently used to treat symptomatic acetabular dysplasia in the adolescent age group. Despite encouraging results, factors predictive of the development of postoperative complications remain poorly understood. The purpose of this study was to investigate whethe...
0
Patient characteristics and outcomes of a hip fracture and concomitant fracture compared with hip fracture alone: results from a United Kingdom teaching hospital
Hip Fx in the Elderly 2019
Introduction: A proportion of patients sustaining hip fractures present with a concomitant fracture. We aimed to evaluate the relationship between patient characteristics and clinical outcomes, in those with a hip and concomitant fracture compared with those sustaining a hip fracture alone from a clinical service regis...
0
Congenital malformations in offspring of women with a history of malignancy
Developmental Dysplasia of the Hip 2020 Review
Background: Survival after malignancy has increased and the question of risks, including risk for congenital malformations for the offspring of these women has become important. Data on congenital malformations in such offspring are limited. Methods: We compared congenital malformation in offspring, born 1994 to 2011 o...
0
The psychological impact of split-thickness skin grafts
DoD PRF (Psychosocial RF)
OBJECTIVE: To measure the psychological distress associated with a split-thickness skin graft (STSG). METHOD: A retrospective postal questionnaire survey of 102 patients who had undergone a STSG procedure within the last 3.5 years. Outcomes measures included the Hospital Anxiety and Depression Scale (HADS), Derriford A...
0
Antimicrobial prophylaxis: Principles and practice
Dental Implant Infection
The goal of antimicrobial prophylaxis is to decrease the risk of procedure-related infection. The prophylactic antibiotic chosen should be active against most of the major pathogens likely to cause an infection. To be effective, inhibitory levels of an antimicrobial agent should be present in blood and tissue at the ti...
1
Reliability of radiological measurements in the assessment of the child's hip
Developmental Dysplasia of the Hip CPG
We investigated the reproducibility of the various radiological methods of assessment of hip dysplasia by making 474 assessments of hips and quantifying the inter-observer and intra-observer variation. There was a wide range of variability between the readings made by different observers and by one observer on two occa...
0
Comparison of 0.15% Ropivacaine/Fentanyl and 0.1% Levobupivacaine/Fentanyl Infused for Postoperative Epidural Analgesia
AAHKS (8) Anesthetic Infiltration
BACKGROUND: In this study we compared the analgesic effects and the incidences of motor weakness and other side effects of postoperative continuous epidural infusion of 0.15% ropivacaine/fentanyl or 0.1% levobupivacaine/fentanyl. METHODS: Sixty seven patients scheduled for elective knee arthroplasty or revision surgery...
0
Postoperative effects of neuromuscular exercise prior to hip orknee arthroplasty - A randomised controlled trial
Surgical Management of Osteoarthritis of the Knee CPG
Purpose: To investigate the postoperative efficacy of a supervised programme of neuromuscular exercise (NEMEX-TJR) prior to hip or knee arthroplasty. Methods: Design: Randomised, assessor-blinded, controlled trial. Setting OUH Svendborg Hospital (regional), Odense University Hospital, Region of Southern Denmark. Partic...
0
Fracture-dislocations of the femoral head
Hip Fx in the Elderly 2019
This review describes bone and nerve injury mechanisms during a femoral head fracture-dislocation and outlines a novel classification system that uses computed tomography scanning (CT scan) to help determine how to best treat these fractures in an emergency setting or in chronic cases. A series of 55 cases with CT scan...
0
Prognostic value of cardiac troponins in elderly patients with hip fracture--a systematic review
Hip Fx in the Elderly 2019
Cardiac troponins can be elevated in cardiac ischemic conditions or other diseases such as pulmonary embolism or renal failure, where they may predict outcome. We hypothesized that cardiac troponins offer useful prognostic information regarding morbidity and mortality in elderly hip fracture patients undergoing surgica...
0
Bone morphogenetic protein (BMP) for fracture healing in adults
Management of Hip Fractures in the Elderly
BACKGROUND: Delay in fracture healing is a complex clinical and economic issue for patients and health services. OBJECTIVES: To assess the incremental effectiveness and costs of bone morphogenetic protein (BMP) on fracture healing in acute fractures and nonunions compared with standards of care. SEARCH STRATEGY: We sea...
0
Distal tibial pilon fractures (AO/OTA type B, and C) treated with the external skeletal and minimal internal fixation method
OAK 3 - Non-arthroplasty tx of OAK
Background/Aim. Distal tibial pilon fractures include extra-articular fractures of the tibial metaphysis and the more severe intra-articular tibial pilon fractures. There is no universal method for treating distal tibial pilon fractures. These fractures are treated by means of open reduction, internal fixation (ORIF) a...
0
Psychometric evaluation of the patient's knee implant performance (PKIP) questionnaire for the assessment of primary total knee arthroplasty
Surgical Management of Osteoarthritis of the Knee CPG
Objectives: The objective of this study was to evaluate the psychometric properties of a new patient-reported measure of knee implant functional performance associated with physical activities prior to and following primary total knee arthroplasty (TKA). The Patient's Knee Implant Performance questionnaire (PKIP) was d...
0
Hemiarthroplasty is an effective surgical method to manage unstable trochanteric fractures in elderly people
Management of Hip Fractures in the Elderly
Trochanteric femoral fractures are a major problem in the elderly because of higher bone fragility due to osteoporosis. Numerous chronic illnesses, which usually affect the elderly, aggravate and complicate their surgical treatment. Trochanteric femoral fractures results in high morbidity and mortality in elderly patie...
1
Efficacy observation on degenerative gonitis treated with triple needling combined with thunder-fire moxibustion
OAK 3 - Non-arthroplasty tx of OAK
Objective: To evaluate the clinical efficacy of degenerative gonitis treated with triple needling combined with thunder-fire moxibustion for better promotion and clinical application. Methods: Ninety-eight patients with degenerative gonitis were randomly divided into a thunder-fire moxibustion group (group A) and an ac...
0
Total knee replacement in patients with significant femoral bowing in the coronal plane: a comparison of conventional and computer-assisted surgery in an Asian population
Surgical Management of Osteoarthritis of the Knee CPG
We conducted a retrospective study to investigate the effect of femoral bowing on the placement of components in total knee replacement (TKR), with regard to its effect on reestablishing the correct mechanical axis, as we hypothesised that computer-assisted total knee replacement (CAS-TKR) would produce more accurate a...
1
Effects of Anesthesia Techniques on Outcomes after Hip Fracture Surgery in Elderly Patients: A Prospective, Randomized, Controlled Trial
Hip Fx in the Elderly 2019
The superiority of distinct anesthesia methods for geriatric hip fracture surgery remains unclear. We evaluated high mobility group box-1 (HMGB1) and interleukin-6 (IL-6) with three different anesthesia methods in elderly patients undergoing hip fracture surgery. Routine blood test findings, postoperative morbidity, an...
0
Open Reduction Techniques for Supracondylar Humerus Fractures in Children
DOD - Acute Comp Syndrome CPG
Supracondylar humerus fractures are the most common elbow fractures in children. Displaced supracondylar humerus fractures that are associated with neurologic and/or vascular injuries are treated with timely reduction through closed techniques. When closed techniques fail, reduction by open methods is indicated. Contro...
0
Comparison of unstable inter-trochanteric femur fracture treated with dynamic hip screw and proximal femur nail
DoD SSI (Surgical Site Infections)
To compare the outcome of unstable intertrochanteric fractures managed by proximal femoral nail (PFN) and dynamic hip screw (DHS). Methodology: The comparative study was done, over the period of two years, involving a total of 108 patients of unstable inter-trochanteric fractures randomly allocated in two groups. One g...
1
Superior and superomedial pedicle wise-pattern reduction mammaplasty: maximizing cosmesis and minimizing complications
Reduction Mammoplasty for Female Breast Hypertrophy
Our center has refined a wise-pattern superior and superomedial pedicle breast reduction technique with predictable quality outcomes giving high patient satisfaction and a very low complication or revision rate. Fifty patients who underwent bilateral superior or superomedial pedicle wise-pattern breast reduction were i...
0
Comparison of glucose and lipid metabolism and bone mineralization in patients with growth hormone deficiency with and without long-term growth hormone replacement
AAHKS (2) Corticosteroids
The effects of long-term growth hormone (GH) substitution in pituitary-insufficient patients with GH deficiency (GHD-pats) on glucose and lipid metabolism and bone mineral density (BMD) have yet to be ascertained. We performed this cross-sectional study comparing GHD-pats with and without long-term GH substitution. We ...
0
Ulnar shortening osteotomy for distal radius malunion
Distal Radius Fractures
UNLABELLED: Background Malunion is a common complication of distal radius fractures. Ulnar shortening osteotomy (USO) may be an effective treatment for distal radius malunion when appropriate indications are observed. Methods The use of USO for treatment of distal radius fracture malunion is described for older patient...
0
Mosaicplasty for the treatment of the osteochondral lesion in the femoral head
Diagnosis and Treatment of Osteochondritis Dissecans AUC
Osteochondral defects of the femoral head are rare and principles of treatment include anatomic reduction, rigid fixation, enhancement of blood supply, and restoration of articular congruity. In this report, we present a case where the defect of the femoral head was treated with surgical dislocation of hip anteriorly a...
0
Incidence of revision surgery in a large cohort of patients with thoracic surgical three-column paddle leads: A retrospective case review
DoD SSI (Surgical Site Infections)
Objectives Spinal cord stimulation (SCS) revision surgery remains common, with a negative impact on cost-effectiveness and outcomes. The primary goal in this report was to retrospectively study the need for revision surgery in a large cohort of patients with newly implanted thoracic surgical three-column paddle leads, ...
0
Rheumatoid arthritis: An integrated acupuncture and energetic approach
PJI DX Updated Search
Rheumatoid arthritis (RA) is an autoimmune disease involving chronic inflammation of the joints. Conventional treatment often involves the early use of DMARDS, many of which have potentially toxic side-effects. For some patients, acupuncture may offer a creative alternative. Drawing from theory and personal experience,...
0
No difference in in vivo polyethylene wear particles between oxidized zirconium and cobalt-chromium femoral component in total knee arthroplasty
Surgical Management of Osteoarthritis of the Knee CPG
Purpose: Polyethylene wear particle generation is one of the most important factors affecting mid- to long-term results of total knee arthroplasties. Oxidized zirconium was introduced as a material for femoral components to reduce polyethylene wear generation. However, an in vivo advantage of oxidized zirconium on poly...
0
Pre- and postoperative function changes in total knee patients
Surgical Management of Osteoarthritis of the Knee CPG
Objective laboratory measurements were obtained preoperatively and up to 24 months postoperatively for 102 patients (140 knees). This longitudinal study was an effort to determine changes in functional status as a result of surgery and rehabilitation. In the main, the function improved in arthritic patients who receive...
1
Social cognitive theory of posttraumatic recovery: the role of perceived self-efficacy
DoD PRF (Psychosocial RF)
The present article integrates findings from diverse studies on the generalized role of perceived coping self-efficacy in recovery from different types of traumatic experiences. They include natural disasters, technological catastrophes, terrorist attacks, military combat, and sexual and criminal assaults. The various ...
0
Prevention of bacterial endocarditis in localised juvenile periodontitis and Papillon-Lefevre syndrome patients
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
The bacterium Actinobacillus actinomycetemcomitans is found in large numbers in subgingival plaque and gingival tissues of patients with LJP and PLS. This bacterium too has been found to cause infective bacterial endocarditis in patients at risk. Antibiotic prophylaxis is necessary for at risk patients with LJP and PLS...
0
Clinical outcome of osteosarcoma with primary total femoral resection
DoD LSA (Limb Salvage vs Amputation)
Primary total femoral resection and reconstruction rarely are indicated for patients with osteosarcoma. We determined the survivorship, complications, and functional outcome of patients with osteosarcomas who had total femoral resections. We evaluated 13 patients with osteosarcomas whose surgical conditions included mu...
0
Colles' fracture and subsequent hip fracture risk
Management of Hip Fractures in the Elderly
The prevention of hip fractures, a major cause of morbidity and mortality in the elderly, is hampered by insufficient knowledge of the population at risk. A Colles' fracture associated with minor trauma is indicative of an overall 50% increase in the risk of a subsequent hip fracture. The relative risk of a subsequent ...
0
Effect of femoral component design on unresurfaced patellas in knee arthroplasty
Surgical Management of Osteoarthritis of the Knee CPG
Three total knee designs were evaluated to test the hypothesis that femoral component design affects the clinical and mechanical functions of the unresurfaced patella after total knee arthroplasty. Patients with the Ortholoc II, Advantim, and Profix femoral components were followed up for as many as 14 years and revisi...
1
The effectiveness of primary bipolar arthroplasty in treatment of unstable intertrochanteric fractures in elderly patients
Hip Fx in the Elderly 2019
BACKGROUND: The treatment of unstable intertrochanteric fracture in the elderly patient is still controversial. Traditionally, internal fixation using a dynamic hip screw was of choice. Recently, some authors advocated the use of cemented bipolar arthroplasty or hemiarthroplasty which results in better functional outco...
0
Single-injection femoral nerve block with 0.25% ropivacaine or 0.25% bupivacaine for postoperative analgesia after total knee replacement or anterior cruciate ligament reconstruction
AAHKS (8) Anesthetic Infiltration
STUDY OBJECTIVE: To investigate the effects of single-injection femoral nerve block (FNB) in postoperative pain after total knee replacement (TKR) and anterior cruciate ligament (ACL) reconstruction. DESIGN: Prospective, randomized, double-blind study. PATIENTS: 96 ASA physical status I, II, and III patients, scheduled...
0
The Role and Use of Estrogens Following Trauma
DoD PRF (Psychosocial RF)
Several lines of evidence indicate that female sex is a protective factor in trauma and hemorrhage. In both clinical and experimental studies, proestrus females have been shown to have better chances of survival and reduced rates of posttraumatic sepsis. Estrogen receptors are expressed in a variety of tissues and exer...
0
Hyaluronic acid for the treatment of osteoarthritis in all joints except the knee: what is the current evidence?
SR for PM on OA of All Extremities
BACKGROUND: The use of intra-articular hyaluronic acid (HA) is a well known treatment in patients with knee osteoarthritis (OA). In other joints, less evidence is available about the efficacy of treatment with intra-articular HA. HA is also used intra-articularly in the metatarsophalangeal-1 joint, the ankle, the hip, ...
0
A neurological symptom survey of patients with type I Gaucher disease
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Gaucher disease is an inborn error of glycosphingolipid metabolism resulting from deficiency of the lysosomal enzyme glucocerebrosidase. The majority of the patients (with type I disease) do not have primary central nervous system involvement. However, several studies have noted that secondary neurological complication...
0
Physiologic changes of compound muscle action potentials related to voluntary contraction and muscle length in carpal tunnel syndrome
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
The affect of muscle length and voluntary contraction upon compound muscle action potentials (CMAPs) in subjects with carpal tunnel syndrome (CTS) has been evaluated. Twenty-five hands in a CTS patient group and 29 hands in a normal subject control group were studied. The CMAPs from the abductor pollicis brevis induced...
0
Temporary epiphysiodesis using the FlexTack TM implant (tension band) featuring a modified explantation technique
Dental Implant Infection
OBJECTIVE: Presenting the implantation of the PediatrOS TM FlexTack TM (Merete, Berlin, Germany) for growth guidance and a modified explantation procedure to facilitate explantation and prevent bone and soft tissue damage., INDICATIONS: Implantation: Genua vara and valga, coxa vara, varus and valgus deviation of the an...
0
Comparative activity of pulsed or continuous estradiol exposure on gene expression and proliferation of normal and tumoral human breast cells
Reduction Mammoplasty for Female Breast Hypertrophy
Intranasal administration of hormone replacement therapy presents an original plasma kinetic profile with transient estrogen levels giving rise to the concept of pulsed therapy. To further understand the molecular effects of this new therapy, we have compared the effects of pulsed and continuous estradiol treatments on...
0
Reconstruction of displaced acromio-clavicular joint dislocations using a triple suture-cerclage: description of a safe and efficient surgical technique
Glenohumeral Joint OA
Purpose: In this retrospective study we investigated the clinical and radiological outcome after operative treatment of acute Rockwood III-V injuries of the AC-joint using two acromioclavicular (AC) cerclages and one coracoclavicular (CC) cerclage with resorbable sutures.Methods: Between 2007 and 2009 a total of 39 pat...
0
Active leflunomide metabolite inhibits interleukin 1beta, tumour necrosis factor alpha, nitric oxide, and metalloproteinase-3 production in activated human synovial tissue cultures
Surgical Management of Osteoarthritis of the Knee CPG
BACKGROUND: Leflunomide is now an approved agent for the management of adult rheumatoid arthritis (RA). Its active metabolite A771726 inhibits de novo pyrimidine biosynthesis. Although considered to be an immunosuppressive agent, its mechanism of action remains obscure. OBJECTIVES: Evaluation of the leflunomide active ...
0
Subdermal neo-umbilicoplasty in abdominoplasty
Panniculectomy & Abdominoplasty CPG
Background: Umbilicoplasty is an important surgical procedure in abdominoplasty, regardless of the technique used. An unaesthetic umbilicus often irreversibly affects surgical outcomes. This study describes the experience of our team with the subdermal neo-umbilicoplasty technique and assesses patient satisfaction with...
0
Epidemiology of humeral fractures in Malawi
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
We analysed and determined retrospectively the location, age, gender and side of the body of humeral fractures from 258 antero-posterior radiographs of all patients aged 3-81 years over a 5-year period. It was observed that 160 fractures occurred on the left side while 98 were on the right side with 156 occurring in ma...
0
Revision arthroplasty in periprosthetic fractures of the proximal femur
DoD SSI (Surgical Site Infections)
OBJECTIVE: Hip revision arthroplasty of a loose stem in the case of Vancouver type B2 and B3 periprosthetic fractures and cerclage wiring of the femoral shaft. INDICATIONS: Vancouver type B2 and B3 periprosthetic fractures of the proximal femur. CONTRAINDICATIONS: Periprosthetic joint infection. Interprosthetic femoral...
1
Dual mobility articulation total hip arthroplasty for displaced neck fracture in elderly with neuromuscular disorder
Hip Fx in the Elderly 2019
PURPOSE: Neuromuscular disease is well known to be at increased risk of complications following hip replacement surgeries. This study is prospectively conducted to investigate clinical performance and survivorship of total hip arthroplasty (THA) using dual mobility articulation in femoral neck fractures of elderly with...
0
Management of acute lower limb ischemia associated with the Angio-Seal arterial puncture closing device
DoD LSA (Limb Salvage vs Amputation)
Arterial percutaneous closure devices (APCD) could lead to severe vascular complications, like acute lower limb ischemia. The aim of this study was to evaluate retrospectively our personal series of acute lower limb ischemia following the use of APCD. From January 2004 to June 2009 the Angio-Seal percutaneous closure d...
0
Exercise and self-management for people with chronic knee, hip or lower back pain: a cluster randomised controlled trial of clinical and cost-effectiveness. Study protocol
OAK 3 - Non-arthroplasty tx of OAK
OBJECTIVES: Chronic musculoskeletal pain and osteoarthritis can significantly limit the functional independence of individuals, and given that 25% of the population experience these problems, the socioeconomic impact is immense. Exercise and self-management have proven benefits for these conditions, but most trials tai...
1
The protective role of maternal posttraumatic growth and cognitive trauma processing among Palestinian mothers and infants
DoD PRF (Psychosocial RF)
War survivors use multiple cognitive and emotional processes to protect their mental health from the negative impacts of trauma. Because mothers and infants may be especially vulnerable to trauma in conditions of war, it is urgent to determine which cognitive and emotional processes are effective for preventing negativ...
1
The Effect of Shelter-in-Place Orders and the COVID-19 Pandemic on Orthopaedic Trauma at a Community Level II Trauma Center
Coronavirus Disease 2019 (COVID-19)
OBJECTIVES: Evaluate the effect of the COVID-19 pandemic and the "shelter-in-place" order on orthopaedic trauma presenting to a community level II trauma center. It is hypothesized the overall number of orthopaedic trauma encounters (OTE), the number of OTEs related to both high and low severity injuries, as well as th...
0
Modifications of the Lejour vertical mammaplasty: analysis of results in 100 consecutive patients
Panniculectomy & Abdominoplasty CPG
The technique of vertical mammaplasty described by Madeline LeJour nearly ten years ago has been slow to gain wide acceptance in the United States. This is perhaps due to the misconception by many that this technique is more technically demanding or harder to reproduce and teach on a consistent basis. This paper descri...
0
Long-term recreational gymnastics provides a clear benefit in age-related functional decline and bone loss. A prospective 6-year study
Management of Hip Fractures in the Elderly
INTRODUCTION: Bone fragility and decreased functional performance are risk factors for osteoporotic fractures. The influence of long-term recreational gymnastics on the maintenance of bone rigidity and physical performance was evaluated. METHODS: One hundred and seven gymnasts and 110 referents (93% of the original sam...
0
Selective activation of small nerve fibers for assessing carpal tunnel syndrome
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Carpal tunnel syndrome (CTS) diagnosis could be improved by selectively activating the different types of nerve fibers traversing the carpal tunnel. The objective of this study is to assess the potential of an anodal blocking technique using tripolar surface electrodes for achieving selective fiber activation and evalu...
0
Influential factors for allogenic blood transfusion after total hip arthroplasty for femoral neck fractures
Management of Hip Fractures in the Elderly
BACKGROUND: Hip arthroplasty surgery as an effective treatment for elderly displaced femoral neck fractures, because of its greater perioperative blood loss, results in many patients requiring blood transfusion, and the transfusion itself has certain costs and risks. How to reduce postoperative allogeneic blood transfu...
0
Ulnar styloid fracture in children: A retrospective study of 46 cases
Distal Radius Fractures
Ulnar styloid fractures are frequently ignored in the treatment of wrist fractures in children. Forty-six untreated ulnar styloid fractures (40 tip and six base fractures) associated with radial injuries (45 patients) were retrospectively analysed. At the removal of the cast, we recorded that 80% had a nonunion of the ...
0
Superomedial pedicle reduction with short scar
Reduction Mammoplasty for Female Breast Hypertrophy
Reduction mammaplasty combining a superomedial pedicle with a circumareolar/vertical pattern skin excision avoids an inferior pedicle that can interfere with vertical scar technique, yet it is flexible enough to allow for a short transverse skin excision. This technique is suitable for small to moderate-size reductions...
1
Meniscus tears treatment: The good, the bad and the ugly-patterns classification and practical guide
AMP (Acute Meniscal Pathology)
Over the years, several studies demonstrated the crucial role of knee menisci in joint biomechanics. As a result, save the meniscus has become the new imperative nowadays, and more and more studies addressed this topic. The huge amount of data on this topic may create confusion in those who want to approach this surger...
0
Hypertension as a complication of circular external fixators
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
Hypertension is not a recognized complication of circular external fixation. The aim of this study was to determine the incidence of hypertension following this procedure. A retrospective review of 57 patients was carried out between January 2006 and May 2010. At least three blood pressure readings were used to define ...
0
Failure of internal fixation of displaced femoral neck fractures in rheumatoid patients
AAHKS (2) Corticosteroids
We reviewed the records and radiographs from 10 hospitals to identify 50 patients with rheumatoid arthritis (RA) who had sustained 52 femoral neck fractures. Most patients were female (88%), elderly (mean age 66 years) and had had severe polyarticular disease for a mean duration of 16 years. Over half had taken systemi...
0
Rock-paper-scissors
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
A study of 20 doctors in their first or second postgraduate year highlighted deficiencies in their knowledge of the nerve supply of the hand and forearm. The children's game rock-paper-scissors (Figs. 1-3) can be used as a simple aide-memoir for the nerve supply to the hand and forearm. The median nerve creates the "ro...
0
Acute Popliteal Artery Occlusion after Revision Total Knee Arthroplasty
DoD LSA (Limb Salvage vs Amputation)
Acute arterial occlusions are a rare complication of total knee arthroplasty (TKA). However, in revision TKA, the risk of such complications is higher and these complications can lead to amputation if not adequately treated. We describe a case of acute popliteal artery occlusion 4 hours after second revision TKA in a p...
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Framingham Risk Scores for coronary heart disease in a cohort of Saudi Arabian men and women with spinal cord injury
DoD PRF (Psychosocial RF)
People with spinal cord injury (SCI) are at increased risk of developing coronary heart disease (CHD). This study aimed at predicting CHD risk in a cohort of Saudi patients with SCI in comparison with patients without SCI and to correlate different demographic and clinical factors with Framingham Risk Score (FRS) in SC...
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Intermittent etidronate therapy to prevent corticosteroid-induced osteoporosis
Management of Hip Fractures in the Elderly
BACKGROUND AND METHODS: Osteoporosis is a recognized complication of corticosteroid therapy. Whether it can be prevented is not known. We conducted a 12-month, randomized, placebo-controlled study of intermittent etidronate (400 mg per day for 14 days) followed by calcium (500 mg per day for 76 days), given for four cy...
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TNFalpha promotes proliferation of human synovial MSCs while maintaining chondrogenic potential
AMP (Acute Meniscal Pathology)
Synovial mesenchymal stem cells (MSCs) are a candidate cell source for cartilage and meniscus regeneration. If we can proliferate synovial MSCs more effectively, we can expand clinical applications to patients with large cartilage and meniscus lesions. TNFalpha is a pleiotropic cytokine that can affect the growth and d...
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Update on Liposuction: What All Plastic Surgeons Should Know
Panniculectomy & Abdominoplasty CPG
LEARNING OBJECTIVES: After studying this article, the participant should be able to: 1. Understand the types of tumescence available for liposuction. 2. Explain the various modalities available for liposuction. 3. Describe the patient selection, staging, and complications associated with debulking liposuction. 4. Descr...
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Adverse effects of glucocorticoids: coagulopathy
AAHKS (2) Corticosteroids
Hypercortisolism is associated with various systemic manifestations, including central obesity, arterial hypertension, glucose intolerance/diabetes mellitus, dyslipidemia, nephrolithiasis, osteoporosis, gonadal dysfunction, susceptibility to infections, psychiatric disorders, and hypercoagulability. The activation of t...
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Treatment of median nerve compression with pulsed radiofrequency: Technique and preliminary results in 21 cases
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Background and aims: The carpal tunnel syndrome (CTS) is the most common entrapment neuropathy. The benefit of non-surgical treatment is limited. Not all patients respond to surgery, complications and failures occurring in 3-19%. We present preliminary results in 21 retrospective cases treated with this pulsed radiofre...
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Random effect modelling of patient-related risk factors in orthopaedic procedures: results from the Dutch nosocomial infection surveillance network 'PREZIES'
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
In the Dutch surveillance for surgical site infections (SSIs), data from 70277 orthopaedic procedures with 1895 SSIs were collected between 1996 and 2003. The aims of this study were: (1) to analyse the trends in SSIs associated with Gram-positive and Gram-negative bacteria; (2) to estimate patient-related risk factors...
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Midterm Outcomes and Predictors of Clinical Success With the KineSpring Knee Implant System
OAK 3 - Non-arthroplasty tx of OAK
The purpose of this study was to (1) evaluate joint pain and function in knee osteoarthritis (OA) patients treated with a joint-sparing, extracapsular implant and (2) identify patient characteristics that influenced clinical outcomes. This study included 99 patients with symptomatic medial knee OA refractory to conserv...
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Wrist arthrodesis for traumatic conditions: a study of plate and local bone graft application
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
This study demonstrates the ability to obtain a predictable and complete wrist arthrodesis using local bone graft and a dorsal plate. The donor site morbidity often seen in using iliac crest graft is eliminated with this method. We examined the use of local distal radius bone grafting alone with dorsal plate fixation a...
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Obesity is independently associated with spinal anesthesia outcomes: a prospective observational study
AAHKS (9/10) Regional Nerve Blocks
The influence of body-mass index (BMI) on spinal anesthesia is still controversial, with discrepant results reported in previous studies. To compare spinal anesthesia in obese and non-obese subjects, the anesthesia profiles in patients who underwent spinal anesthesia using intrathecal hyperbaric bupivacaine were compar...
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Structural allograft reconstruction of the foot and ankle after tumor resections
DoD LSA (Limb Salvage vs Amputation)
BACKGROUND: Structural allografts have been used to correct deformities or to fill bone defects secondary to tumor excisions, trauma, osteochondral lesions, or intercalary arthrodesis. However, the quality of published evidence supporting the use of allograft transplantation in foot and ankle surgery has been reported ...
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A descriptive study of women injured by hand-arm vibration
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
The aim of this study was to describe the symptoms and the prognosis of vibration injuries in women. The investigation was based on a study of 374 women who had reported an injury due to hand-arm vibration to the Social Insurance Office or had received financial compensation from the Swedish Labor Market Insurance sche...
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Heterotopic bone formation after total hip arthroplasty in patients with primary or secondary coxarthrosis
Management of Hip Fractures in the Elderly
Heterotopic bone formation was investigated in 392 Charnley low-friction total hip arthroplasties. A multivariate linear regression analysis was used to account for the influence of co-variables: sex, age at surgery, postoperative treatment with antiinflammatory drugs during at least the first 2 weeks, and previous ips...
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Reimplantation of infected total hip arthroplasties in the absence of antibiotic cement
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
Twenty-two patients with deep infection of the hip were reimplanted and followed for a minimum of 3 years. All reimplantations were done without antibiotic-impregnated cement. Nine were done using cemented and 13 using cementless components. Two patients had recurrent infection. Both of these had primary Pseudomonas in...
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Effects of insomnia disorder and knee osteoarthritis on resting and pain-evoked inflammatory markers
OAK 3 - Non-arthroplasty tx of OAK
Osteoarthritis is the most prevalent arthritic condition. Systemic inflammatory cytokines appear to have an important role in the onset and maintenance of the disease. Sleep disturbances are prevalent in osteoarthritis and associated with alterations in systemic inflammatory cytokines, suggesting a common pathophysiolo...
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Antimicrobial Prophylaxis with Combat-Related Open Soft-Tissue Injuries
DoD SSI (Surgical Site Infections)
INTRODUCTION: All Department of Defense (DoD) guidance documents recommend cefazolin or clindamycin as post-trauma antibiotic prophylaxis for open soft-tissue injuries. Although not advocated, some patients with open soft-tissue injuries also received expanded Gram-negative coverage (EGN) prophylaxis based on the judgm...
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A new technique in the treatment of distal radius fractures: the Micronail
Distal Radius Fractures
OBJECTIVES: In 2006, an intramedullar titanium osteosynthesis for the stabilization of distal radius fractures was introduced in The Netherlands: the Micronail. The Micronail can be used in approximately 30% of distal radius fracture treatments. This article presents the introduction of this new treatment, and first cl...
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The Infection Risk during Normal Knee Arthroscopy Performed without the Use of Antibiotics for Preventative Purposes
AMP (Acute Meniscal Pathology)
Background: Despite the fact that previous research has indicated that giving prophylactic antibiotics to patients having normal knee arthroscopy may not be necessary and may, in fact, cause more problems than it solves, it is yet usual practice to do so. The objective of this study is to assess the incidence of surgic...
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Non-standard vision measures predict mortality in elders: the Smith-Kettlewell Institute (SKI) study
Upper Eyelid and Brow Surgery
PURPOSE: To determine which vision tests predict mortality within 10 years in a community-based elderly sample. METHODS: Nine hundred residents of Marin County, California 58 to 101 years of age (mean 75 years at baseline), underwent a battery of tests, including high contrast acuity, low contrast acuity, low contrast/...
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Clinical features of the degenerate meniscus with the results of meniscectomy
AMP (Acute Meniscal Pathology)
A series of 172 patients with an unambiguous diagnosis of horizontal cleavage lesion is reviewed, the average duration of which was 4 1/2 years. Although all the patients complained of pain, night pain and mechanical instability were not invariable. Joint line tenderness was the commonest physical sign. Whereas all but...