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0 | Osteoarthritis in elderly knees | Surgical Management of Osteoarthritis of the Knee CPG | This review of osteoarthritis of the knees in the elderly touches on the clinical presentation and examination, epidemiology, etiology, radiologic characteristics, and origin of the pain. The discussion includes drug treatment, intra-articular drug use, nondrug therapy, and the role of arthroscopy and joint lavage |
1 | Prospective randomized comparison of endobutton versus cross-pin femoral fixation in hamstring anterior cruciate ligament reconstruction with 2-year follow-up | Anterior Cruciate Ligament Injuries CPG | BACKGROUND: To determine if there is a different clinical outcome after TransFix versus endobutton femoral fixation in hamstring anterior cruciate ligament (ACL) reconstruction. METHODS: Twenty-nine patients were randomized into either Endobutton (Smith & Nephew, Andover, MA, USA) (n= 13) or TransFix (Arthrex, Naples, ... |
0 | Precision and accuracy of measuring changes in bone mineral density by dual-energy X-ray absorptiometry | Management of Hip Fractures in the Elderly | Long-term precision of two Hologic DXA scanners was derived from repeated clinical measurements. With typical subjects, the long-term coefficients of variation were about twice the short-term. The accuracy of the measurement of changes was compromised by anomalies, but this did not seriously affect clinical conclusions... |
0 | Magnetic Resonance Imaging Findings in Small Patella Syndrome | Osteochondritis Dissecans 2020 Review | Small patella syndrome (SPS) is characterized by aplasia or hypoplasia of the patella and pelvic girdle abnormalities, including bilateral absence or delayed ossification of the ischiopubic junction and infra-acetabular axe-cut notches. Here, we report a case of SPS in a 26-year-old female. Magnetic resonance image (MR... |
1 | A longitudinal pilot study of resilience in Canadian military personnel | DoD PRF (Psychosocial RF) | Research on psychological resilience is important for occupations involving routine exposure to trauma or critical events. Such research can allow for the identification of factors to target in training, education and intervention programs, as well as groups that may be at higher risk for mental health problems. Althou... |
0 | The vertical mammaplasty: a reappraisal of the technique and its complications | Panniculectomy & Abdominoplasty CPG | Since 1989, superior pedicle vertical scar mammaplasty as described by Lejour has been used in the authors' department as the only technique for breast reduction. From 1991 through 1994, a series of 170 consecutive patients (330 breasts) underwent an operation. In these patients, minor complications were observed in 30... |
0 | Muscle strength, functional performance, and self-reported outcomes four years after arthroscopic partial meniscectomy in middle-aged patients | AMP (Acute Meniscal Pathology) | OBJECTIVE: To examine thigh muscle strength, functional performance, and self-reported outcome in patients with nontraumatic meniscus tears 4 years after operation, and to study the impact of a strength deficit on self-reported outcome and evaluate the feasibility of 3 performance tests in this patient group.
METHODS: ... |
0 | Presentation of occult Chiari I malformation following spinal anesthesia | Surgical Management of Osteoarthritis of the Knee CPG | Chiari I malformation (CM-I) manifests with tonsillar herniation below foramen magnum. These patients are at high risk of respiratory depression and bulbar dysfunction in the perioperative period with underlying obstructive sleep apnea. However, the safe use of both general and regional anaesthesia has been documented ... |
0 | The presence of total knee or hip replacements due to osteoarthritis enhances the positive association between hand osteoarthritis and atherosclerosis in women: the AGES-Reykjavik study | Surgical Management of Osteoarthritis of the Knee CPG | OBJECTIVE: This study examines the relationship between total knee replacements (TKR), total hip replacements (THR) or replacements of either joint (total joint replacement; TJR) due to osteoarthritis and atherosclerosis in a large population-based study. METHODS: The participants were 2195 men and 2975 women, mean age... |
0 | Advances that are changing the diagnosis and treatment of malignant bone tumors | MSTS 2018 - Femur Mets and MM | PURPOSE OF REVIEW: Several neoplastic conditions may affect bone. These include primary bone tumors as well as metastatic disease from distant primary sites. Often, these entities produce symptoms that may be difficult to distinguish from those of various rheumatologic entities. The purpose of this review is to discuss... |
0 | Medium-term results after complex intra-articular fractures of the tibial plateau | OAK 3 - Non-arthroplasty tx of OAK | Background: To present the medium-term results of intra-articular, bicondylar AO/OTA classification type C fractures of the tibial plateau in a retrospective study at a level-1 trauma center in 22 patients with 23 fractures. Methods: Demographic data for the patients and details of current clinical and radiological fol... |
0 | Three-year experience with alendronate treatment in postmenopausal osteoporotic Japanese women with or without type 2 diabetes | Management of Hip Fractures in the Elderly | Aims: The increased risk of fractures in patients with type 2 diabetes can partly be explained by poor bone quality and extra-skeletal factors. A retrospective study was conducted to compare the outcome of alendronate (ALN) treatment for 3 years in postmenopausal osteoporotic Japanese women with or without type 2 diabe... |
0 | The diagnostic and predictive role of NLR, d-NLR and PLR in COVID-19 patients | Coronavirus Disease 2019 (COVID-19) | AIM: To accumulate evidence that indicated the key role played by virus-triggered inflammation in the 2019-novel coronavirus disease (COVID-19) which emerged in Wuhan City and rapidly spread throughout China. METHODS: Age, neutrophil(NEU)-to-lymphocyte (LYM) ratio (NLR), lymphocyte-to-monocyte (MON) ratio, platelet-to-... |
0 | Osteoporosis and vertebral compression fractures-continued missed opportunities | Distal Radius Fractures | BACKGROUND CONTEXT: Untreated osteoporosis causes decreased bone mineral density, which predisposes to fragility fractures. Low-energy vertebral compression fractures are the most common type of osteoporotic fragility fracture. Prior studies have shown that only one-quarter of patients diagnosed with an osteoporotic fr... |
0 | The use of T-cell directed cellular therapies in Australia | MSTS 2018 - Femur Mets and MM | The use of cellular therapy in Australia has been limited by the number of facilities deemed acceptable for the preparation of T cells for immunotherapy. In spite of this, a number of trials using cellular immunotherapy have been conducted and a number are underway or are in the planning stage, and selected examples of... |
0 | The Collaborative Hospital Transfusion Study: variations in use of autologous blood account for hospital differences in red cell use during primary hip and knee surgery | Management of Hip Fractures in the Elderly | BACKGROUND: Red cell use in patients undergoing Diagnosis Related Group (DRG) 209 procedures (major joint and limb reconstruction procedures of the lower extremities) has been shown to have large, unexplained interhospital variations.STUDY DESIGN AND METHODS: Abstracted records of 2590 consecutive DRG 209 patients at f... |
0 | Risk factors for infection in total knee replacement surgery at hospital Kuala Lumpur | Surgical Management of Osteoarthritis of the Knee CPG | One hundred primary TKR surgeries done between January 1994 and December 1999 were reviewed after a mean follow-up of 37.4 months. The rate of superficial and deep wound infection were 2% and 9% respectively. The most common organism in wound infection was Staphylococcus aureus. The factors that were significantly asso... |
0 | Anesthetic effects of adding intrathecal neostigmine or magnesium sulphate to bupivacaine in patients under lower extremities surgeries | Surgical Management of Osteoarthritis of the Knee CPG | Background: Regional anesthesia is widely used to perform different surgical procedures including those performed on the extremities. In this study, the anesthetic effects of adding intrathecal neostigmine or magnesium sulphate to bupivacaine in patients under lower extremities surgeries were assessed. Materials and Me... |
0 | Patterns of cancer care and association with survival among younger adolescents and young adults: A population-based retrospective cohort study | MSTS 2022 - Metastatic Disease of the Humerus | Background: Younger adolescents and young adults (AYA) may receive care from either adult or pediatric oncologists. We explored patterns of care in this population and whether survival is associated with provider type. Methods: Utilizing the California Cancer Registry, we examined a cohort of 9,993 AYAs diagnosed with ... |
0 | Rehabilitation of burned patients with bilateral above-knee amputations | DoD LSA (Limb Salvage vs Amputation) | Bilateral above the knee amputations occur rarely in the seriously burned population. In a 6-month interval, two patients were treated in our Burn Center whose trauma necessitated bilateral above-knee amputations. This led us to review our experience with such cases. A review of 5018 patients treated over a 28-year per... |
0 | Changes in cortical grey matter density associated with long-standing retinal visual field defects | Upper Eyelid and Brow Surgery | Retinal lesions caused by eye diseases such as glaucoma and age-related macular degeneration can, over time, eliminate stimulation of parts of the visual cortex. This could lead to degeneration of inactive cortical neuronal tissue, but this has not been established in humans. Here, we used magnetic resonance imaging to... |
0 | An evolutionary perspective of the knee | AMP (Acute Meniscal Pathology) | The complex asymmetrical design of the human knee is ancient in origin. The distinctive characteristics of this design were well established more than 300 million years ago. The knees of most classes of tetrapods exhibit similar morphological characteristics, including a bicondylar cam-shaped distal part of the femur, ... |
0 | Continuous nerve blocks for outpatient knee surgery | Surgical Management of Osteoarthritis of the Knee CPG | In outpatient knee surgery, perineural catheter techniques are an important advance to further ensure a comfortable same-day discharge after procedures typically associated with significant pain. For outpatients, attention should be directed both to the multimodal treatment of pain as well as to the multimodal prophyla... |
1 | Outcomes of 807 Thompson hip hemiarthroplasty procedures and the effect of surgical approach on dislocation rates | Hip Fx in the Elderly 2019 | The majority of displaced intracapsular fractures in our unit are managed with a Thompson hip hemiarthroplasty. Recent UK guidance from the National Institute for Health and Care Excellence has, however, advised against the continued used of the Thompson implant in patients with hip fracture. The aim of this study was ... |
0 | Perioperative versus Preoperative Chemotherapy with Surgery in Patients with Resectable Squamous Cell Carcinoma of Esophagus: A Phase III Randomized Trial | Reconstruction After Skin Cancer | BACKGROUND: Perioperative chemotherapy for resectable squamous cell carcinoma of esophagus remains elusive. Thus, we assessed whether a perioperative regimen of paclitaxel, cisplatin, and 5- fluorouracil (PCF) improved outcomes among patients with curable squamous cell carcinoma of esophagus comparing with preoperative... |
1 | Pre-injection of hyaluronic acid does not affect the systemic effects of intra-articular depot betamethasone injection at the knee joint | OAK 3 - Non-arthroplasty tx of OAK | Intra-articular injection (IAI) of both hyaluronic acid (HA) and depot-steroid preparations had the advantage of quick and prolonged favorable effects on pain relief among patients with symptomatic osteoarthritis of the knee (OAK). The effect of IAI of HA on the systemic effects of the intra-articular steroids had not ... |
0 | Sphenoethmoidal mucocele presenting with unilateral visual loss | Upper Eyelid and Brow Surgery | BACKGROUND: Sphenoethmoidal sinus mucocele causing uniocular progressive vision loss is a rare entity and was first described by Bery in 1985. It is generally diagnosed in its advanced stage when the patients develop subjective ophthalmic symptoms. CASE: A 43-year-old male presented to our institute for further evaluat... |
1 | 151 endoprosthetic reconstructions for patients with primary tumors involving bone | MSTS 2018 - Femur Mets and MM | As part of the UCLA limb salvage program, 151 patients received 151 endoprostheses for primary tumors involving bone. Follow-up of all patients was to death (56), revision (21), or a minimum two years for the 74 additional survivors (range: 24-114 months; mean: 52 months). Endoprosthetic replacements were of the distal... |
0 | Prospective safety surveillance of GH-deficient adults: Comparison of GH-treated vs untreated patients | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Context: In clinical practice, the safety profile of GH replacement therapy for GH-deficient adults compared with no replacement therapy is unknown. Objective: The objective of this study was to compare adverse events (AEs) in GH-deficient adults who were GH-treated with those in GH-deficient adults who did not receive... |
0 | A technical innovation for improving identification of the trackers by the LED cameras in navigation-assisted total knee arthroplasty | Surgical Management of Osteoarthritis of the Knee CPG | OBJECTIVE: To reduce the operating time in computer-assisted navigated total knee replacement (TKR), by improving communication between the infrared camera and the trackers placed on the patient. MATERIALS AND METHODS: The innovation involves placing a routinely used laser pointer on top of the camera, so that the infr... |
1 | End-to-side anastomosis for limb salvage in the single artery of a traumatized extremity | DoD LSA (Limb Salvage vs Amputation) | BACKGROUND: The purpose of this article is to describe and highlight our experience of end-to-side anastomosis technique in such cases for limbs salvage in the single artery of a traumatized extremity with free-flap transfer. METHODS: Thirty-two traumatized patients in need of free-flap transfer for their extremity rec... |
0 | Are older breast carcinoma survivors willing to take hormone replacement therapy? | Management of Hip Fractures in the Elderly | BACKGROUND: Breast carcinoma survivors are the largest segment of the expanding cancer survivor community. As a result, there has been increasing discussion of the safety and efficacy of hormone replacement therapy for women with a past history of breast carcinoma. Little is known about the willingness of older breast ... |
0 | Treatment of Infected Forearm Nonunions With Large Complete Segmental Defects Using Bulk Allograft and Intramedullary Fixation | DoD SSI (Surgical Site Infections) | PURPOSE: The purpose of this study is to report the results of a series of infected forearm nonunions treated from 1998 to 2012 using a staged reconstruction technique.
METHODS: At a median of 42 months follow-up, 7 patients who had an average segmental defect of 4.9 cm (range, 2.3-10.4 cm) were available for clinical ... |
1 | Abdominoplasty with total abdominal liposuction for patients with massive weight loss | Panniculectomy & Abdominoplasty CPG | BACKGROUND: Massive weight loss after bariatric surgery is associated with significant skin excess, laxity, and ptosis over the abdomen. Good results have been achieved with abdominoplasty and circumferential lipectomy. However, blood transfusions are sometimes needed, and patients may require long hospital stays. Furt... |
0 | Using Mesh to Reinforce the Abdominal Wall in Abdominal Free Flaps for Breast Reconstruction: Is There a Benefit? What are the Risks? | Acellular Dermal Matrix | INTRODUCTION: Abdominal wall integrity may be compromised after abdominal flap harvest for breast reconstruction, leading to bulging or herniation due to weakening of the abdominal wall and dissection through the rectus muscle. Mesh can be used to reinforce the abdominal wall to reduce the risk of hernia formation post... |
0 | Self-management practices among primary care patients with musculoskeletal pain and depression | Management of Hip Fractures in the Elderly | The objective of this study was to assess the effect of clinical depression on pain self-management practices. We employed a cross-sectional analysis of baseline data from the Stepped Care for Affective disorders and Musculoskeletal Pain (SCAMP) study. Participants included 250 patients with pain and comorbid depressio... |
0 | Effect of PCL on flexion-extension gaps and femoral component decision in TKA | Surgical Management of Osteoarthritis of the Knee CPG | This study was done to evaluate the change of medial-lateral gap in flexion and extension after posterior cruciate ligament (PCL) release in severely deformed knees and to determine how PCL release affects bone resection, rotation, and size of the femoral component and polyethylene thickness in converting to a PCL-sacr... |
0 | Distribution of type VI collagen in chondrocyte microenvironment: study of chondrons isolated from human normal and degenerative articular cartilage and cultured chondrocytes | Surgical Management of Osteoarthritis of the Knee CPG | The chondron is the microanatomical unit composed of a chondrocyte and its pericellular microenvironment (PCME), including the pericellular matrix and capsule. In the present study, we extracted chondrons from human articular cartilages and investigated the relationship between the distribution of the matrix molecules,... |
0 | Mind and body: Mental health and health related quality of life in SCI caregivers from Neiva, Colombia | DoD PRF (Psychosocial RF) | BACKGROUND: Despite the body of research on caregivers of individuals with various types of disabilities, SCI caregivers have received comparably less attention, especially in regions like Latin America.
OBJECTIVE: The purpose of this study was to examine the association between HRQOL and mental health in SCI caregiver... |
0 | Antibiotics and postoperative abscesses in complicated appendicitis: is there any association? | Patrick’s pharmacoepidemiology project | INTRODUCTION: Complicated appendicitis has significant infective postoperative morbidity. There is no universally-accepted antibiotic regime, although traditionally, triple antibiotics are recommended. Our complicated appendicitis clinical pathway recommends ceftriaxone and metronidazole. The study aimed to determine i... |
0 | Intra- and Extra-Articular Deformity of Lower Limb: Tibial Condylar Valgus Osteotomy (TCVO) and Distal Tibial Oblique Osteotomy (DTOO) for Reconstruction of Joint Congruency | AMP (Acute Meniscal Pathology) | Osteotomies are the established surgical procedure for the deformity of the lower limb induced by osteoarthritis (OA) of the knee and ankle. Closed-wedge (CW) and open-wedge (OW) high tibial osteotomy (HTO) are extra-articular surgery, which aim to shift the mechanical axis from medial to slightly lateral and reduce th... |
0 | Cerebrospinal fluid markers of neuroinflammation in delirium: a role for interleukin-1beta in delirium after hip fracture | Hip Fx in the Elderly 2019 | OBJECTIVE: Exaggerated central nervous system (CNS) inflammatory responses to peripheral stressors may be implicated in delirium. This study hypothesised that the IL-1beta family is involved in delirium, predicting increased levels of interleukin-1beta (IL-1beta) and decreased IL-1 receptor antagonist (IL-1ra) in the c... |
0 | Cortical encroachment after cephalomedullary nailing of the proximal femur: evaluation of a more anatomic radius of curvature | Hip Fx in the Elderly 2019 | OBJECTIVES: : A unique complication of using full-length intramedullary nails for pertrochanteric and subtrochanteric femur fractures is nail penetration of the anterior cortex at the distal end of the femur because of a mismatch of the anatomic femoral bow with that of currently available cephalomedullary nails (CMNs)... |
0 | Disassembly of a modular femoral component after femoral head prosthetic replacement | Management of Hip Fractures in the Elderly | We report a rare case of a taper-locked femoral inner head that have been completely separated from the stem neck. A 76-year-old man who had hip fracture of the right hip had disassembly of inner head and stem neck after revision of bipolar hip prosthesis. This force could have been amplified by the pumping phenomenon ... |
0 | Cephalomedullary fixation for intertrochanteric fractures: an operative technical tip | Hip Fx in the Elderly 2019 | Intertrochanteric fracture is the most common hip fractures in elderly population. Cephalomedullary fixation, including proximal femoral nail antirotation (PFNA) and gamma nail, is commonly used in the treatment of intertrochanteric fractures. One of difficulties encountered in operation is insertion of the guide wire ... |
1 | Work-related critical incidents in hospital-based health care providers and the risk of post-traumatic stress symptoms, anxiety, and depression: A meta-analysis | Coronavirus Disease 2019 (COVID-19) | This meta-analysis reviewed existing data on the impact of work-related critical incidents in hospital-based health care professionals. Work-related critical incidents may induce post-traumatic stress symptoms or even post-traumatic stress disorder (PTSD), anxiety, and depression and may negatively affect health care p... |
0 | Male breast cancer. Evolution of treatment and prognostic factors. Analysis of 489 cases | MSTS 2018 - Femur Mets and MM | BACKGROUND: Infiltrating MBC represents less than 1% of all male cancers. Our study details clinico-pathological features, treatments and prognostic factors in a large French cohort.
MATERIAL AND METHODS: Four hundred and eighty-nine patients were collected from 1990 to 2005. Median age was 66 years (34% over 70 years)... |
0 | Bone metastases and quality of life | MSTS 2018 - Femur Mets and MM | Bone metastases are a common consequence of many malignancies. Few clinical trials have evaluated quality of life (QOL) as an endpoint in studies directed to medical or radiotherapy interventions for bone metastases. Given the lack of well-developed bone metastases specific QOL instruments, our group initiated the deve... |
0 | Climbing stairs with a walking frame - A locomotion proposal for patients unable to master walking on crutches | Management of Hip Fractures in the Elderly | It is assumed that walking canes, tripods, quadrupeds and crutches can be helpful in the case of stair climbing. Walking frames and supporters are counted as equipment used only on flat ground. The aim of the research is to prove the possibility for a patient, who cannot walk on crutches, of climbing stairs with a supp... |
0 | Survivorship and clinical outcome of Birmingham hip resurfacing: a minimum ten years' follow-up | Hip Fx in the Elderly 2019 | INTRODUCTION: Resurfacing as a percentage of total hip arthroplasty rose from 5.6 % in 2001 to 8.9 % in 2005 in Australia. During the same period the resurfacing to conventional prosthesis rose from 19.6 % to 29 % in the younger age group (less than 55 years). Long term (more than ten years) functional results of BHR a... |
0 | Distal humeral epiphyseal separation in young children: an often-missed fracture-radiographic signs and ultrasound confirmatory diagnosis | Pediatric Supracondylar Humerus Fracture 2020 Review | OBJECTIVE. Distal humeral epiphyseal separation is rare and often misdiagnosed. The purpose of this study was to summarize an experience with radiography and ultrasound of distal humeral epiphyseal separation. MATERIALS AND METHODS. The records of all children younger than 36 months with the diagnosis of distal humeral... |
0 | Impact of negative clinical trial results for vertebroplasty on vertebral augmentation procedure rates | SR for PM on OA of All Extremities | Background: Vertebroplasty and kyphoplasty are procedures for treating vertebral compression fractures (VCFs). In August 2009, 2 randomized trials in the New England Journal of Medicine found that vertebroplasty did not reduce pain or disability relative to a sham procedure among patients with osteoporotic VCFs.Study D... |
1 | Should embolectomy be performed in late acute lower extremity arterial occlusions? | DOD - Acute Comp Syndrome CPG | BACKGROUND: We analyzed the embolectomy results and complications of patients who were operated on after a diagnosis of late acute arterial occlusion of lower extremities.
METHODS: A total of 122 patients operated on in our clinic between 2004 and 2009 for late acute arterial occlusion were included in the study. Late ... |
0 | CXCR4: A New Player in an Old Scene? | MSTS 2018 - Femur Mets and MM | Transmembrane C-X-C chemokine receptor 4 (CXCR4) and its ligand C-X-C motif chemokine 12 (CXCL12) came into focus in many solid cancers, allowing a more fundamental diagnostic and therapeutic approach by modulating the immune response against cancer cells. CXCR4 and CXCL12 mediate cell proliferation, migration, and met... |
0 | Conservative treatment of extra-articular Colles' type fractures of the distal radius: prospective study | Distal Radius Fractures | AIM: To determine the anatomical and functional results of conservative treatment of extra-articular Colles' type fractures of the distal radius and the borderline value of each anatomical parameter for the best possible correlation with functional end result.
METHODS: This prospective study included 54 patients. Stand... |
0 | Emerging treatment approaches for myeloma-related bone disease | MSTS 2018 - Femur Mets and MM | INTRODUCTION: Multiple myeloma is characterized by the presence of osteolytic lesions that leads to devastating skeletal-related events in the majority of patients. Myeloma bone disease is attributed to increased osteoclastic and suppressed osteoblastic activity. Areas covered: Bisphosphonates remain the main treatment... |
0 | Readmission following ventral hernia repair: a model derived from the ACS-NSQIP datasets | Panniculectomy & Abdominoplasty CPG | BACKGROUND: Institutions are now incentivized to decrease rates of preventable readmissions. The purpose of this study was to examine readmissions following open ventral hernia repair (VHR), to ultimately create a model to preoperatively identify high-risk patients. STUDY DESIGN: Utilizing the 2011 and 2012 ACS-NSQIP d... |
0 | Free medial meniscal fragment which mimics the dislocated bucket-handle tear on MRI | AMP (Acute Meniscal Pathology) | The bucket-handle meniscal tear is a specific type of meniscal injuries which has specific signs on MRI. An attached fragment displaced away from the meniscus with any type of tear causes bucket-handle tear of the meniscus. Magnetic resonance imaging (MRI) is the most commonly used diagnostic tool for meniscal injuries... |
0 | Patient perceptions of access to care and referrals to specialists: a comparison of African-American and white older patients with knee and hip osteoarthritis | Surgical Management of Osteoarthritis of the Knee CPG | BACKGROUND: There is a marked racial difference in the use of knee and hip replacement for osteoarthritis (OA). The reasons for this disparity remain unclear. We examined how African-American and white patients with symptomatic OA of the knee and/or hip compare with respect to their perceptions of care for knee and hip... |
0 | Patient-reported outcomes after Silastic replacement of the trapezium for osteoarthritis | Glenohumeral Joint OA | This retrospective study evaluated 69 Swanson trapezium replacements performed between 1990 and 2009 for trapeziometacarpal osteoarthritis in 58 patients. Pain and function were assessed using the Michigan Hand Questionnaire and the Disability of the Arm, Shoulder and Hand questionnaire. Patients had a mean age of 62 y... |
0 | Diagnosis and Clinical Presentation of Osteoarthritis | AAHKS (5) Gabapentinoids | Osteoarthritis (OA), the commonest arthropathy, targets the knees, hips, finger interphalangeal joints, thumb bases, first metatarsophalangeal joints, and spinal facet joints, and displays marked heterogeneity of clinical presentation. Signs of OA include coarse crepitus, bony enlargement, reduced range of movement, an... |
1 | Lumbar spinal stenosis impairs function following total knee arthroplasty | Surgical Management of Osteoarthritis of the Knee CPG | Lumbar spinal stenosis is a common cause of lower back and leg pain in older adults. Stenosis is not considered a contraindication for total knee arthroplasty (TKA); however, it is unclear whether it is associated with less than optimal postoperative outcomes. In a multicenter review of TKAs, 115 patients with lumbar d... |
0 | Endoplasmic Reticulum Stress in Osteoarthritis: A Novel Perspective on the Pathogenesis and Treatment | AMP (Acute Meniscal Pathology) | Osteoarthritis (OA), the most common degenerative joint disease, causes an enormous socioeconomic burden due to its disabling properties and high prevalence. Increasing evidence suggests that OA is a whole-joint disease involving cartilage degradation, synovitis, meniscal lesions, and subchondral bone remodeling. Endop... |
0 | Comparison of Single Intra-articular Injection of Hyruan-One With Hylan G-F 20 in Knee Osteoarthritis | OAK 3 - Non-arthroplasty tx of OAK | We compare the efficacy of intraâ?articular injection of Hyruanâ?One with Hylan Gâ?F 20 and placebo (NSS) controlled in a doubleâ?blind RCT. |
0 | Rigorous development does not ensure that guidelines are acceptable to a panel of knowledgeable providers | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | BACKGROUND: Rigorous guideline development methods are designed to produce recommendations that are relevant to common clinical situations and consistent with evidence and expert understanding, thereby promoting guidelines' acceptability to providers. No studies have examined whether this technical quality consistently... |
0 | Managing dental patients with joint prostheses | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | A literature review explored the possible association of late infections of major joint prostheses and dental bacteremias. The review showed transient dental bacteremias had little or no role in causing late infections of prosthetic joint replacements. However, patients with certain systemic conditions or complications... |
0 | Discoid Meniscus: Diagnosis and Management | AMP (Acute Meniscal Pathology) | Discoid lateral meniscus is a common abnormal meniscal variant in children. Detailed history and physical examination combined with an MRI of the knee predictably diagnose a discoid meniscus. The clinical presentation varies from being asymptomatic to snapping, locking, and causing severe pain and swelling of the knee.... |
0 | Management of true recurrent carpal tunnel syndrome: is it worthwhile to bring vascularized tissue? | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Since 1989, 13 consecutive cases of true recurrent carpal tunnel have been operated on. Average delay before reoperation was 20 months (3 to 60 months). Intraoperative findings were univocal: extensive fibrosis with nerve adhesion to the roof of the carpal tunnel and a lack of nerve gliding. Surgery performed was: exte... |
0 | Quadriceps tendon rupture after total knee arthroplasty. Prevalence, complications, and outcomes | Surgical Management of Osteoarthritis of the Knee CPG | BACKGROUND: There is relatively little information about quadriceps tendon tears after total knee arthroplasty. The purpose of this study was to determine the prevalence of this condition and the outcomes of patients who had a tear of the quadriceps tendon after a total knee arthroplasty. METHODS: From a cohort of 23,8... |
0 | Retrograde nailing of fresh and pathologic humeral shaft fractures with a new unreamed humeral nail (UHN) | The Treatment of Pediatric Supracondylar Humerus Fractures AUC | Intramedullary nailing of humeral shaft fractures is still a controversial issue. The comments and experience with antegrade nailing vary from enthusiasm to criticism. Main criticisms concern the damage of the rotator cuff and articular cartilage and possible impingement syndrome. The new unreamed humeral nail (UHN) is... |
0 | Changes in Healthcare Utilization After Etanercept Initiation in Patients with Rheumatoid Arthritis: A Retrospective Claims Analysis | AAHKS (2) Corticosteroids | INTRODUCTION: Effective treatment for rheumatoid arthritis (RA) may lead to lower overall and RA-related healthcare utilization. We evaluated healthcare utilization before and after initiation of the tumor necrosis factor inhibitor etanercept in patients with moderate to severe RA.
METHODS: This retrospective cohort st... |
0 | Allergy Considerations in Implanted Neuromodulation Devices | Dental Implant Infection | OBJECTIVES: Allergic reactions are rare and poorly understood complications of neuromodulation device implantation. There are currently no guidelines for management of allergic reactions to these devices and their components. Here we review the published cases of allergic reactions to implanted neuromodulatory devices ... |
0 | STING promotes senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the NF-kappaB signaling pathway | AMP (Acute Meniscal Pathology) | Damaged deoxyribonucleic acid (DNA) is a primary pathologic factor for osteoarthritis (OA); however, the mechanism by which DNA damage drives OA is unclear. Previous research demonstrated that the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) participates in DNA damage response. As a result, the... |
1 | The Effect of Perioperative Corticosteroids in Total Hip Arthroplasty: A Prospective Double-Blind Placebo Controlled Pilot Study | AAHKS (2) Corticosteroids | BACKGROUND: Surgery produces a rapid rise in interleukin 6 (IL-6) which may increase the risk of deep vein thrombosis and medical complications. Perioperative corticosteroids suppress IL-6 release in patients undergoing total knee arthroplasty. This study evaluates the effects of a perioperative corticosteroid regimen ... |
0 | Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis | Management of Hip Fractures in the Elderly | BACKGROUND: Due to their known effects on bone metabolism, Vitamin D and related compounds have been proposed for the prevention of osteoporosis and fractures. OBJECTIVES: To determine the effects of supplementation with Vitamin D or a Vitamin D analogue in the prevention of fractures of the axial and appendicular skel... |
0 | Neurophysiological changes in COPD patients with chronic respiratory insufficieny | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Chronic hypoxemia is known to cause peripheral neuropathy (PNP) in chronic obstructive pulmonary disease (COPD) patients. We aimed to know how often PNP is encountered in such patients and the changes in the central nervous system (CNS) if any. We enrolled 32 patients (30M, 2F; mean age (plus or minus) SD: 61.5 (plus o... |
0 | Hy-Flex II total knee system and range of motion | Surgical Management of Osteoarthritis of the Knee CPG | We developed the Hy-Flex II total knee and ligament balancing system (Hy-Flex II total knee) which provides (1) a flexion angle of at least 120 degrees or more, (2) a range of motion (ROM) comparable to or greater than that before surgery, and (3) occasional full flexion. The system design has several features: small p... |
0 | Familial amyloid polyneuropathy (Finnish type) in a Japanese family: Clinical features and immunocytochemical studies | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Familial amyloid polyneuropathy (FAP: type IV), known as familial amyloidosis of the Finnish type (FAF), is very rare and reported only in a few countries. The gelsolin mutation G654A is most frequent causative gene in FAF family. The clinical phenotype of FAF possesses several neurological characteristics with multipl... |
0 | Coping strategies and self-efficacy as predictors of outcome in osteoarthritis: a systematic review | SR for PM on OA of All Extremities | OBJECTIVE: Systematically to review the literature, investigating the prognostic value of self-efficacy and coping strategies used by adults with osteoarthritis (OA) recruited within the community or primary care. METHODS: An online electronic search was performed from inception to August 2009, using EMBASE, CINAHL, Ps... |
1 | The correlation of radiographic outcome to functional outcome following fracture of the distal radius in elderly patients: A literature review | Distal Radius Fractures | Introduction: Fractures of the distal radius are common in the elderly population. Elderly patients have been considered to be functionally low-demand, but as the population becomes more active, expectations of outcomes may be increasing. The aim of this review was to determine whether there is any correlation between ... |
0 | Seasonal variations in incidence of fractures among elderly people | Management of Hip Fractures in the Elderly | OBJECTIVE: To investigate seasonal variations in the incidence of fall related fractures among people 65 years and older. POPULATION AND METHODS: A prospective, population based cohort study was performed on people aged 65 years and older followed up from 1990 to 1997, a total of 459,904 person years. Cases were identi... |
0 | Meniscus repair: up-to-date advances in stem cell-based therapy | AMP (Acute Meniscal Pathology) | The meniscus is a semilunar fibrocartilage between the tibia and femur that is essential for the structural and functional integrity of the keen joint. In addition to pain and knee joint dysfunction, meniscus injuries can also lead to degenerative changes of the knee joint such as osteoarthritis, which further affect p... |
0 | Early failure in total hip arthroplasty | Hip Fx Time to Surgery | Although some patients experience a success rate greater than 90% after total hip arthroplasty, others require revision surgery within 5 years after the index procedure. The purpose of our study was to analyze the failure mechanisms in patients who had revision surgery within 5 years after index total hip arthroplasty.... |
0 | An integrated analysis of five double-blind, randomized controlled trials evaluating the safety and efficacy of a hyaluronan product for intra-articular injection in osteoarthritis of the knee | SR for PM on OA of All Extremities | OBJECTIVE: Five double-blind, randomized, saline-controlled trials (RCTs) were included in the United States marketing application for an intra-articular hyaluronan (IA-HA) product for the treatment of osteoarthritis (OA) of the knee. We report an integrated analysis of the primary Case Report Form (CRF) data from thes... |
0 | Association of Medial Meniscal Volume With Decreased Joint Space Width After Medial Opening-Wedge High Tibial Osteotomy | AMP (Acute Meniscal Pathology) | Background: Medial opening-wedge high tibial osteotomy (MOWHTO) reduces contact stress by altering the weightbearing axis from the medial to the lateral compartment, relieves knee pain, and slows the progression of osteoarthritis.
Purpose/Hypothesis: To evaluate whether the volume of the medial meniscus affects outcome... |
0 | Hospitalisation and comorbidities in Parkinson's disease: A large Australian retrospective study | DoD PRF (Psychosocial RF) | Objectives: Patients with Parkinson's disease (PD) require higher levels of care during hospitalisation. Management of comorbidities in these patients aims to optimise function while minimising complications. The objective of this study was to examine patterns of hospitalisation of patients with PD in NSW with regards ... |
1 | Rates of infection and revision in patients with renal disease undergoing total knee replacement in Scotland | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | We undertook a study to determine the rates of infection and revision of total knee replacement (TKR) in patients with renal failure, renal transplantation and those undergoing renal dialysis in Scotland. The overall early and late infection rates were 1.10% and 2.19% compared with 1.06% and 2.01%, respectively, for no... |
0 | Retinal fixation impairment in diabetic macular edema | Upper Eyelid and Brow Surgery | PURPOSE: To evaluate the characteristics of retinal fixation in patients with diabetic macular edema using microperimetry. METHODS: One hundred seventy nine eyes (98 patients) with untreated diabetic macular edema underwent best corrected visual acuity determination (Early Treatment Diabetic Retinopathy Study charts), ... |
0 | Versatility of the sural fasciocutaneous flap in the coverage of lower third leg and hind foot defects | DoD LSA (Limb Salvage vs Amputation) | BACKGROUND: Reconstruction of soft tissue defects of the lower third of the leg, the heel and the hind foot remains a challenge. The distally based sural artery fasciocutaneous flap has been used effectively to resurface these defects. In many instances, it has obviated the need for free tissue transfer. OBJECTIVE: The... |
0 | Local control of ductal carcinoma in situ based on tumor and patient characteristics: the surgeon's perspective | MSTS 2018 - Femur Mets and MM | Ductal carcinoma in situ (DCIS) is a disease whose manifestations are largely confined to in-breast pathology. Management strategies therefore focus on various combinations of local therapy: mastectomy, lumpectomy alone, and lumpectomy followed by breast irradiation. Although DCIS does not carry an inherent risk of dis... |
1 | Vertical reduction mammaplasty: preventing skin redundancy at the vertical scar in women with large breasts or poor skin elasticity | Reduction Mammoplasty for Female Breast Hypertrophy | The authors describe a vertical reduction mammaplasty technique for avoiding skin excess at the vertical scar. Conical projection of the breast is achieved by cranial to caudal gland-shaping sutures. Excision of redundant skin is performed in a triangular pattern, creating bilateral dog ears. Resection of these dog ear... |
0 | Does the frailty index predict discharge disposition and length of stay at the hospital and rehabilitation facilities? | Hip Fx in the Elderly 2019 | INTRODUCTION: Many geriatric hip fracture patients utilize significant healthcare resources and require an extensive recovery period after surgery. There is an increasing awareness that measuring frailty in geriatric patients may be useful in predicting mortality and perioperative complications and may be useful in hel... |
0 | Serum levels of total-RANKL in multiple myeloma | MSTS 2018 - Femur Mets and MM | Background: Receptor activator of nuclear factor-κB ligand (RANKL) plays a key role in osteoclast activation in myeloma bone disease. The increased expression of RANKL in the bone marrow microenvironment was demonstrated in several studies, but there are only rare data on circulating RANKL levels in patients with mult... |
0 | Five-year follow-up of macular morphologic changes after rhegmatogenous retinal detachment repair: Fourier domain OCT findings | Upper Eyelid and Brow Surgery | PURPOSE: To evaluate serially long-term macular morphologic changes after successful macula-involving rhegmatogenous retinal detachment repair and correlate changes with macular function. METHODS: Repeat Fourier domain optical coherence tomography (FD OCT) imaging and microperimetry (MP-1) testing of 8 of the initial c... |
0 | Revision total hip arthroplasty in juvenile chronic arthritis: 17 revisions in 11 patients followed for 4-12 years | Dental Implant Infection | BACKGROUND: Revision total hip arthroplasty (THA) in patients with juvenile chronic arthritis (JCA) is complicated by the young age of the patient, poor bone stock and small physical proportions. We report the complications and outcome of a prospective series of 17 revision THAs in Charnley class C JCA patients., METHO... |
1 | The need for preoperative closed reduction of unstable, dorsally displaced distal radius fractures in view of pain perception and postoperative results | Distal Radius Fractures | INTERVENTION: Intervention 1: Clost reduction and cast Immobilisation with analgosedation before operation Intervention 2: Cast immobilisation without previous closed reduction before operation CONDITION: S52.51 â? [generalization S52.5: Fracture of lower end of radius] PRIMARY OUTCOME: Difference of the pain level be... |
0 | Paratricipital-triceps splitting "two-window" approach for distal humerus fractures | The Treatment of Pediatric Supracondylar Humerus Fractures AUC | Commonly, distal transcondylar and intra-articular distal humerus fractures are treated through a transolecranon approach. Other options for exposure, open reduction, and internal fixation exist to prevent the reported complications of olecranon osteotomy. The technique of triceps sparing access, as it has been reporte... |
1 | Hematological variables and iron status in abdominoplasty after bariatric surgery | Panniculectomy & Abdominoplasty CPG | BACKGROUND: Abdominoplasty, the treatment for abdominal wall deformity stemming from weight loss after bariatric surgery, can cause postoperative anemia. Moreover, bariatric surgery has been associated with iron deficiency, which by itself can compromise erythropoiesis. The objective of this research is to describe the... |
0 | Traumatic and Degenerative Meniscus Tears Have Different Gene Expression Signatures | OAK 3 - Non-arthroplasty tx of OAK | BACKGROUND: Meniscus tears are classified as traumatic or degenerative based on the tear pattern. There is little evidence demonstrating biological differences between the 2 tear types.
HYPOTHESIS: Gene expression signatures in the injured meniscus are different between traumatic (vertical) and degenerative (complex, h... |
0 | Incidence and severity of infections after closed reduction and external fixation of proximal humeral fractures | DoD SSI (Surgical Site Infections) | OBJECTIVES: This study aimed to evaluate the incidence and severity of pin tract infections in a series of patients treated by Closed reduction external fixation (CREF) for proximal humeral fractures.
DESIGN: Retrospective review of medical charts and radiographs.
SETTING: Academic level-1 trauma center.
PATIENTS: Fort... |
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