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0 | Olefin Isomers of a Triazole Bisphosphonate Synergistically Inhibit Geranylgeranyl Diphosphate Synthase | MSTS 2018 - Femur Mets and MM | The isoprenoid donor for protein geranylgeranylation reactions, geranylgeranyl diphosphate (GGDP), is the product of the enzyme GGDP synthase (GGDPS) that condenses farnesyl diphosphate (FDP) and isopentenyl pyrophosphate. GGDPS inhibition is of interest from a therapeutic perspective for multiple myeloma because we ha... |
1 | The effect of a preoperative exercise and education program on functional recovery, health related quality of life, and health service utilization following primary total knee arthroplasty | Surgical Management of Osteoarthritis of the Knee CPG | OBJECTIVE: To determine the effectiveness of a preoperative exercise/education program on functional recovery, health related quality of life (HRQOL), health service utilization, and costs following primary total knee arthroplasty (TKA). METHODS: One hundred thirty-one subjects were randomized to either the control (n ... |
0 | Changes in C-reactive protein and erythrocyte sedimentation rate after hip fractures | Management of Hip Fractures in the Elderly | Serial measurements of C-reactive protein (CRP) levels and erythrocyte sedimentation rates (ESR) were performed during the week after operation in 140 patients with hip fractures. There was no selection, and patients with minor or major complications before or after operation were included. In uncomplicated cases, the ... |
0 | Madelung Disease Epidemiology and Clinical Characteristics: a Systemic Review | Panniculectomy & Abdominoplasty CPG | BACKGROUND: Madelung disease is a rare lipid metabolic disorder, and most cases are sporadically reported. There are currently no systematic reviews summarizing the epidemiological and clinical characteristics of this disease. The purpose of the current article is to extract and analyze the existing evidence concerning... |
0 | Rehabilitation of breast cancer patients | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Multimodality treatment in patients with breast cancer, alike the disease progression process, results in numerous side effects that significantly affect the quality of everyday life. Studies have shown a correlation between the quality of life and survival rates. To prevent or maximally reduce these effects rehabilita... |
0 | Reconsideration of the Epicanthus: Evolution of the Eyelid and the Devolutional Concept of Asian Blepharoplasty | Upper Eyelid and Brow Surgery | Double eyelidplasty is the most frequent cosmetic procedure for Asians; however, the epicanthal fold has been a conundrum that has limited the cosmetic results of Asian blepharoplasty. To achieve satisfactory results in an Asian double eyelidplasty, the key is an understanding of the true nature of the epicanthus. We p... |
0 | Surgical management of articular cartilage defects in the knee | AMP (Acute Meniscal Pathology) | The treatment of isolated cartilage lesions of the knee is based on several underlying principles, including a predictable reduction in the patient's symptoms, improvements in function and joint congruence, and prevention of progressive damage. Surgical options for cartilage restoration are described as palliative trea... |
0 | Prevention of hip fractures by external hip protectors: a randomized controlled trial | Management of Hip Fractures in the Elderly | CONTEXT: Several randomized controlled trials have been performed to examine the effectiveness of external hip protectors in reducing the incid ence of hip fractures, but the results are controversial. OBJECTIVE: To examine the effectiveness of hip protectors in reducing the incidence of hip fractures in an elderly hig... |
1 | Advanced renal cell carcinoma: Pathology and systemic therapy with a new role of zoledronic acid in management of skeletal metastases | MSTS 2018 - Femur Mets and MM | Renal race carcinoma (RCC) continues to represent a major therapeutic challenge. There is still observed the increased rate of incidence of RCC at the level of 2% per annum. Unfortunately, approximately 30% of patients develop distant metastases at first presentation. Progression of RCC accounts for additional 20% of c... |
0 | Scintigraphic assessment of patellar viability in total knee arthroplasty after lateral release | Surgical Management of Osteoarthritis of the Knee CPG | To what extent lateral retinacular release done in total knee arthroplasty compromises patellar viability has been debated. This study is a prospective study to assess patellar viability using Technetium-99m methylene diphosphate (Tc-99m MDP) scintigraphy. Between 2005 and 2006, 59 patients (72 knees) who underwent pri... |
0 | Short-term survival of cementless Oxford unicondylar knee arthroplasty based on the Finnish Arthroplasty Register | OAK 3 - Non-arthroplasty tx of OAK | Background: Cementless unicondylar knee arthroplasty (UKA) was introduced to secure long-term fixation and reduce the risk of revision. Experience with cementless UKA fixation is limited. Methods: The short-term survival (up to five years) of cementless Oxford UKA was assessed using data from the Finish Arthroplasty Re... |
1 | The relationship between diagnostic value of chest computed tomography imaging and symptom duration in COVID infection | Coronavirus Disease 2019 (COVID-19) | OBJECTIVES: Severe acute respiratory syndrome-coronovirus-2 is a global public health problem, in which early diagnosis is required to prevent the spread of infection. In this study, we aimed to reveal the diagnostic value of chest computed tomography (CT) imaging with respect to symptom duration. METHODS: This retrosp... |
0 | Non-Inferiority Study Comparing 3 Weekly Injections of SUPARTZ® vs 3 Weekly Injections of Euflexxa® for Knee OA | OAK 3 - Non-arthroplasty tx of OAK | The purpose of this study is to demonstrate nonâ?inferiority of three weekly intraâ?articular injections of SUPARTZ to three weekly intraâ?articular injections of Euflexxa for the relief of knee joint pain in subjects with osteoarthritis (OA) of the knee as measured by the VAS (0â?100 mm) Western Ontario and McMast... |
0 | Statins and the risk of herpes zoster: a population-based cohort study | PJI DX Updated Search | BACKGROUND: Statins are widely used lipid-lowering drugs with immunomodulatory properties that may favor reactivation of latent varicella-zoster virus infection. However, whether statins increase the risk of herpes zoster is unknown. METHODS: We conducted a population-based retrospective cohort study of Ontario residen... |
0 | Core self-evaluations as personal factors in the World Health Organizationâ??s International Classification of Functioning, Disability and Health model: An application in persons with spinal cord injury | DoD PRF (Psychosocial RF) | Purpose: To evaluate Chan, Gelman, Ditchman, Kim, and Chiuâ??s (2009) revised World Health Organizationâ??s International Classification of Functioning, Disability and Health (ICF) model using core self-evaluations (CSE) to account for Personal Factors in persons with spinal cord injury (SCI). Method: One hundred eight... |
0 | Difficulty of pinching behind the back: an atypical symptom of carpal tunnel syndrome related to a specific wrist position. Two case reports | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Carpal tunnel syndrome (CTS) may be overlooked in the absence of typical sensory symptoms. Two patients with CTS lacked the attendant sensory symptoms but experienced difficulties performing a pinching action behind the back (manipulation of the buckle of a baby sling or the hook of a brassiere), a mode of pinching tha... |
0 | Functional outcome of meniscal-bearing total ankle replacement: a gait analysis study | AMP (Acute Meniscal Pathology) | BACKGROUND: Most clinical studies on total ankle replacement (TAR) report assessments based on traditional clinical scores or radiographic analysis. Only a few studies have used modern instrumentation for quantitative functional analysis during the execution of activities of daily living. The aim of this study was to u... |
0 | Accuracy of Palpation-Guided Catheter Placement for Muscle Pressure Measurements in Suspected Deep Posterior Chronic Exertional Compartment Syndrome of the Lower Leg: A Magnetic Resonance Imaging Study | DOD - Acute Comp Syndrome CPG | BACKGROUND: A diagnosis of lower leg deep posterior chronic exertional compartment syndrome (dp-CECS) is made by a dynamic pressure measurement. The insertion of a pressure catheter is guided by anatomic landmarks (freehand) or by ultrasound. The catheter tip is ideally positioned in the tibialis posterior muscle (TP).... |
1 | Combining clinical factors and quantitative ultrasound improves the detection of women both at low and high risk for hip fracture | Management of Hip Fractures in the Elderly | We hypothesized that combining clinical risk factors (CRF) with the heel stiffness index (SI) measured via quantitative ultrasound (QUS) would improve the detection of women both at low and high risk for hip fracture. Categorizing women by risk score improved the specificity of detection to 42.4%, versus 33.8% using CR... |
0 | Relationship between sarcopenia and fracture risks in obese postmenopausal women | DoD PRF (Psychosocial RF) | It is known that obesity is inversely correlated with fracture risk. It remains unclear if a low muscle mass (sarcopenia) modulates the relationship between obesity and bone mass density. Twenty-seven obese women were matched for total fat mass (± 0.5 kg) and age (± 4 yrs) and divided in 3 equal groups: class II sarc... |
0 | Managements of giant cell tumor within the distal radius: A retrospective study of 58 cases from a single center | Distal Radius Fractures | Background: Giant cell tumor of bone (GCTB) in distal radius is a benign but invasive bone tumor characterized by strong aggressive behavior and frequent recurrence.
Methods: To identify recurrence related risk factors and decide suitable surgical strategy, the potential tumor- and treatment-specific factors, post-oper... |
0 | The influence of surgical factors on dislocation of the meniscal bearing after Oxford medial unicompartmental knee replacement: a case-control study | AMP (Acute Meniscal Pathology) | The aim of this study was to evaluate the risk factors for dislocation of the bearing after a mobile-bearing Oxford medial unicompartmental knee replacement (UKR) and to test the hypothesis that surgical factors, as measured from post-operative radiographs, are associated with its dislocation From a total of 480 UKRs p... |
0 | Combined 18F-fluoride and 18F-FDG PET/CT scanning for evaluation of malignancy: results of an international multicenter trial | MSTS AUC - Based on ACR Lit Review | UNLABELLED: (18)F-FDG PET/CT is used in a variety of cancers, but because of variable rates of glucose metabolism, not all cancers are reliably identified. (18)F(-) PET/CT allows for the acquisition of highly sensitive and specific images of the skeleton. We prospectively evaluated combined (18)F(-)/(18)F-FDG as a sing... |
1 | Results of distal radial fractures treated by intra-focal pin fixation | Distal Radius Fractures | INTRODUCTION: Kapandji described intra-focal pin fixation of distal radial fracture in which the pins pass through the fracture line and anchor to the far cortex. These pins aid reduction of the fracture and maintain reduction by buttressing the distal fragments.
MATERIALS AND METHODS: Between January 1996 to December ... |
0 | Intra-Operative Bone Stability Test | Pediatric Supracondylar Humerus Fracture 2020 Review | Fractures of the supercondylar humerus are the most common elbow fracture in pediatrics. Management of this injury would be aided if surgeons could reliably test fracture stability intraoperatively after pinning. A transverse supracondylar humerus fracture model was created using 3 adult cadaver upper-extremity specime... |
0 | Declining incidence of medication-related osteonecrosis of the jaw in patients with cancer | MSTS 2018 - Femur Mets and MM | Context: Medication-related osteonecrosis of the jaw (MRONJ) is an infrequent, but severely debilitating condition. Given the significant morbidity attributable to MRONJ and the challenges associated with its management, prevention is crucial. Objective: We sought to evaluate the effectiveness of an active dental inter... |
0 | Anatomy of the flexor retinaculum | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | For an accurate definition of the anatomic limits of the carpal tunnel, 26 cadaver upper extremities were studied by gross (10), histologic (3), and radiographic (13) methods. The mean proximal limit of the central portion of the flexor retinaculum was 11 mm distal to the capitate-lunate joint, and the mean distal limi... |
0 | Anti-tumour effects of bisphosphonates--what have we learned from in vivo models? | MSTS 2018 - Femur Mets and MM | Bisphosphonates are extensively used to treat cancer-induced bone disease in a range of solid tumours and multiple myeloma, where they reduce the incidence of skeletal related events and improve patients' quality of life. Recent reports indicate that bisphosphonates may also prevent recurrence of breast cancer at perip... |
0 | Dental practice during a world cruise: characterisation of oral health at sea | Dental Implant Infection | AIMS: To describe oral health of passengers and crew attending the dental service aboard during a two months world cruise., METHODS: In a retrospective, descriptive epidemiologic study design the routine documentation of all dental treatment provided at sea was analysed after the voyage. Subjects were n = 57 passengers... |
1 | An analysis of risk factors associated with failure of below knee amputations | DoD LSA (Limb Salvage vs Amputation) | BACKGROUND: Below knee amputation (BKA) is often required in patients with critical limb ischemia. When such a procedure fails, an above knee revision (AKA) is required. This can cause further complications in this group of patients, who already have a high incidence of medical co-morbidities. METHODS: Case records of ... |
0 | Open treatment of transscaphoid perilunate fracture dislocations | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Open treatment of transscaphoid perilunate dislocations attains good results if appropriate reduction and fixation is achieved. A combined volar and dorsal approach provides excellent exposure and enables restoration of ligamentous and skeletal anatomy. Closed treatment for this injury is not advocated unless it is use... |
0 | Association of knee muscle strength with lower extremity dysfunction in patients with osteoarthritis: A comparison with rheumatoid arthritis patients and healthy controls | OAK 3 - Non-arthroplasty tx of OAK | Objectives: This study aims to evaluate the relationship between knee muscle strength and lower limb dysfunction in patients with osteoarthritis (OA) in the lower limbs. Patients and methods: A total of 126 subjects including 42 with OA in the lower limbs, 42 with rheumatoid arthritis (RA) and 42 healthy controls (mean... |
0 | Appendicular skeletal muscle in hospitalised hip-fracture patients: development and cross-validation of anthropometric prediction equations against dual-energy X-ray absorptiometry | Hip Fx in the Elderly 2019 | BACKGROUND: accurate and practical assessment methods for assessing appendicular skeletal muscle (ASM) is of clinical importance for the diagnosis of geriatric syndromes associated with skeletal muscle wasting.
OBJECTIVES: the purpose of this study was to develop and cross-validate novel anthropometric prediction equat... |
0 | Ultrasound assessment of the effectiveness of carpal tunnel release on median nerve deformation | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | To assess the biomechanical effect of carpal tunnel release (CTR), we evaluated the deformation and displacement patterns of the median nerve before and after CTR in carpal tunnel syndrome patients. Sixteen wrists of 14 idiopathic carpal tunnel syndrome patients who had open CTR and twenty-six wrists of 13 asymptomatic... |
0 | Integrated care pathway: the prevention and management of pressure ulcers | Management of Hip Fractures in the Elderly | The introduction of this pathway for the prevention and management of pressure ulcers was influenced by the development of the pathway for the management of a patient with a fractured neck of femur. Systematic documentation of preventative measures for patients with a fractured neck of femur helped reduce the incidence... |
0 | Current issues in prevention of infective endocarditis | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | Prevention of infective endocarditis continues to concern health care providers in many specialties. The well-known lack of primary clinical trials in this area is not expected to change. Therefore, the evolution of recommendations and practice must be based on theoretic considerations and continuing assessment of seco... |
0 | Post-traumatic Articular Cartilage Lesions Increase at Second-look Arthroscopy Following Primary Anterior Cruciate Ligament Reconstruction | OAK 3 - Non-arthroplasty tx of OAK | Anterior cruciate ligament (ACL) reconstruction (ACLR) after ACL rupture improves the instability of the knee joint and decreases mechanical stress to the meniscus and articular cartilage. However, there are reports that post-traumatic osteoarthritis (PTOA) is observed over time following ACLR. In this study, we assess... |
0 | Quantitative measures of meniscus extrusion predict incident radiographic knee osteoarthritis--data from the Osteoarthritis Initiative | AMP (Acute Meniscal Pathology) | OBJECTIVE: To test the hypothesis that quantitative measures of meniscus extrusion predict incident radiographic knee osteoarthritis (KOA), prior to the advent of radiographic disease.
METHODS: 206 knees with incident radiographic KOA (Kellgren Lawrence Grade (KLG) 0 or 1 at baseline, developing KLG 2 or greater with a... |
0 | Positive and negative factors for the treatment outcomes following total ankle arthroplasty? A systematic review | OAK 3 - Non-arthroplasty tx of OAK | Background: Patient selection, surgeon's experience and implant design play an integral role and affect the treatment outcomes of total ankle arthroplasty (TAA). The aims of this study were to investigate the positive and negative attributes that correlate with different clinical and radiographic outcomes. Methods: Eig... |
0 | Hip Fracture Trends in America Between 2009 and 2016 | Hip Fx in the Elderly 2019 | Background: Hip fractures are a common condition associated with high morbidity and mortality. In this study, we assess (1) yearly incidences, (2) demographic factors, (3) postoperative outcomes, (4) primary diagnoses, and (5) primary procedures. Materials and Methods: The National Inpatient Sample was queried for pati... |
0 | Which one of the benign tumors and tumor-like lesions located in long bones needs prophylactic fixation during surgery? | MSTS 2022 - Metastatic Disease of the Humerus | OBJECTIVES: This study aims to define the simultaneous prophylactic fixation indications of benign tumors and tumor-like lesions located in long bones that were treated by curettage and grafting/cementing.
PATIENTS AND METHODS: Fifty-six patients (33 males, 23 females; mean age 30.9+/-15.9; range, 15 to 65 years) who w... |
0 | A study of 44 patients with subtrochanteric fractures treated using long nail and cerclage cables | Hip Fx in the Elderly 2019 | OBJECTIVE: This study aims to demonstrate that the use of long cephalomedullary nail and cerclage cables represents a good strategy in order to reduce the high risk of nonunion of the most displaced subtrochanteric fractures.
METHODS: This retrospective study examines 44 patients with average follow-up of 23 months, wi... |
0 | Choosing treatment options for patients with relapsed/refractory multiple myeloma | MSTS 2018 - Femur Mets and MM | Multiple myeloma (MM) is a clonal plasma cell disorder that is still incurable using conventional treatments. Over the last decade, advances in front-line therapy have led to an increase in survival, but there are still some doubts in the case of relapsed/refractory disease. We searched the PubMed database for articles... |
1 | The impact of arterial vessel injuries associated with pediatric supracondylar humeral fractures | Pediatric Supracondylar Humerus Fracture 2020 Review | BACKGROUND: Pediatric supracondylar humeral fractures are regularly complicated by vascular compromise. However, the treatment regimen for pulseless hands with good capillary refill time is discussed controversially. The aim of the present study was to present our treatment strategy in a series of children sustaining s... |
0 | Pedicled anterolateral thigh flap for reconstruction after radical groin dissection | Reconstruction After Skin Cancer | INTRODUCTION: Inguinal lymphadenectomy is performed for the treatment of nodal metastases from squamous cell carcinoma of the penis and other tumors of the trunk and lower extremity. Malignant skin infiltration requires wide resection, producing a defect requiring complex soft-tissue reconstruction. We have used a pedi... |
1 | Effects of ibuprofen on molecular markers of cartilage and synovium turnover in patients with knee osteoarthritis | Non-Arthroplasty Treatment of Osteoarthritis of the Knee AUC | OBJECTIVE: The aim of this study was to evaluate the effect of ibuprofen on the urinary excretion of C-terminal crosslinking telopeptide of type II collagen (CTX-II) and urinary glucosyl galactosyl pyridinoline (Glc-Gal-PYD), two new molecular markers of cartilage and synovial tissue metabolism, respectively, in patien... |
0 | ReMove-It - Efficacy study of rehabilitation with telemedical assisted movement therapy after lower extremity intervention | OAK 3 - Non-arthroplasty tx of OAK | INTERVENTION: Intervention 1: Threeâ?month telemedically assisted exercise therapy at home, based on the system MeineReha® (after inpatient rehabilitation) The telemedicine training program can be used at home on a television. Here the trainee is facing the screen and gets its exercises shown. Using an installed onâ?... |
0 | Early functional recovery following bilateral total knee replacement versus selective unilateral total knee replacement | Surgical Management of Osteoarthritis of the Knee CPG | BACKGROUND: Early functional recovery following bilateral total knee replacement or selective unilateral after total knee arthroplasty are still controversial. OBJECTIVE: To evaluate the function recovery differences of patients with osteoarthritis knees after bilateral total knee replacement or selective unilateral to... |
1 | Infective complications in tumour endoprostheses implanted after pathological fracture of the limbs | MSTS 2018 - Femur Mets and MM | Introduction Pathological fractures represent an adverse prognostic factor in primary and metastatic bone tumours. The purpose of this study was to evaluate the results of tumour silverâ?coated prosthesis implanted after pathological fractures. Materials and methods A retrospective analysis was conducted on 30 patient... |
0 | Evaluation of the need for a fracture liaison service in a patient-centered medical home | Hip Fx in the Elderly 2019 | Objectives: To evaluate the need for a fracture liaison service (FLS) based on postfracture care in a patient-centered medical home (PCMH). Methods: Patients in a PCMH who presented to a local 763-bed community teaching hospital with fragility fracture of the hip, spine, or forearm between January 1, 2013, and December... |
0 | Efficacy and safety of tanezumab added on to diclofenac in patients with knee or hip osteoarthritis (NCT00864097) | Surgical Management of Osteoarthritis of the Knee CPG | Background/Purpose: Tanezumab (TZB), a monoclonal antibody that inhibits nerve growth factor, reduces hip or knee osteoarthritis (OA) pain. A European randomized, double-blind, controlled multicenter study was conducted to evaluate efficacy and safety of intravenous (IV) TZB added to oral diclofenac sustained release (... |
0 | Long-term Effect of a Single Subcritical Knee Injury: Increasing the Risk of Anterior Cruciate Ligament Rupture and Osteoarthritis | Osteochondritis Dissecans 2020 Review | BACKGROUND: Rupture of the anterior cruciate ligament (ACL) is a well-known risk factor for the development of posttraumatic osteoarthritis (PTOA), but patients with the "same injury" can have vastly different trajectories for the onset and progression of disease. Minor subcritical injuries preceding the critical injur... |
1 | Factors affecting anterior knee pain following anatomic double-bundle anterior cruciate ligament reconstruction | Anterior Cruciate Ligament Injuries CPG | PURPOSE: The purpose of this study was to evaluate the prevalence of anterior knee pain in anatomic double-bundle anterior cruciate ligament (ACL) reconstruction and to identify critical factors affecting postoperative anterior knee pain development. METHODS: Subjects comprised 171 patients (171 knees) who underwent an... |
0 | Single dose oral tiaprofenic acid for acute postoperative pain in adults | SR for PM on OA of All Extremities | Background: Tiaprofenic acid is a a non-steroidal anti-inflammatory drug (NSAID). It is widely available around the world, with indications for osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, periarticular disorders, and strains and sprains. This review sought to evaluate the efficacy and safety of oral t... |
0 | In situ allograft replacement of infected infrarenal aortic prosthetic grafts: results in forty-three patients | Surgical Management of Osteoarthritis of the Knee CPG | PURPOSE: Dissatisfaction with conventional methods of treatment of infected infrarenal aortic prosthetic grafts and excellent long-term results reported by heart surgeons after allograft replacement for management of infections involving the ascending aorta have prompted us to investigate allograft replacement in the m... |
1 | A comparative analysis of work-related outcomes after humeral hemiarthroplasty and reverse total shoulder arthroplasty | Glenohumeral Joint OA | Background The return to work of young patients undergoing shoulder arthroplasty is increasingly important. Whereas studies have shown superior outcomes of reverse total shoulder arthroplasty (RTSA) compared with humeral hemiarthroplasty (HHA), no prior literature has compared RTSA with HHA in regard to return to work.... |
0 | Risk factors for perioperative hyperglycemia in primary hip and knee replacements | Surgical Management of Osteoarthritis of the Knee CPG | Background and purpose - Perioperative hyperglycemia has been associated with adverse outcomes in several fields of surgery. In this observational study, we identified factors associated with an increased risk of hyperglycemia following hip and knee replacement. Patients and methods - We prospectively monitored changes... |
0 | Clinical implications of skeletal muscle blood-oxygenation-level-dependent (BOLD) MRI | DOD - Acute Comp Syndrome CPG | Blood-oxygenation-level-dependent (BOLD) contrast in magnetic resonance (MR) imaging of skeletal muscle mainly depends on changes of oxygen saturation in the microcirculation. In recent years, an increasing number of studies have evaluated the clinical relevance of skeletal muscle BOLD MR imaging in vascular diseases, ... |
0 | Single minimal incision fasciotomy for chronic exertional compartment syndrome of the lower leg | DOD - Acute Comp Syndrome CPG | BACKGROUND: Chronic exertional compartment syndrome (CECS) involves a painful increase in compartment pressure caused by exercise and relieved by rest, common in athletes. The most common site for CECS in the lower limbs is the anterior leg compartment. The aim of this study is to evaluate the outcomes of a single mini... |
0 | Biomechanical comparison of volar locked plate constructs using smooth and threaded locking pegs | Distal Radius Fractures | The goal of this study was to determine whether there is any biomechanical difference in terms of construct strength with axial loading between volar fixed-angle locking plates with threaded locking vs smooth locking pegs. The control group comprised 7 cadaveric specimens with threaded locking pegs, and the test group ... |
0 | Dispersion of the distal compound muscle action potential in chronic inflammatory demyelinating polyneuropathy and carpal tunnel syndrome | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Median neuropathy at the wrist can confound the electrodiagnosis of chronic inflammatory demyelinating polyneuropathy (CIDP), since both conditions can prolong median distal motor latency. Dispersion of the distal CMAP (DCMAP) has recently emerged as a potentially useful adjunct in the electrodiagnosis of CIDP, with go... |
0 | Efficacy of a protocol to distinguish risk of serious bacterial infection in the outpatient evaluation of febrile young infants | Patrick’s pharmacoepidemiology project | A study of 534 febrile infants ages 4 to 8 weeks evaluated for sepsis assessed the efficacy of the Milwaukee Protocol (MP) for selecting patients at low risk for serious bacterial infection (SBI) who might benefit from outpatient management. Two groups were compared: 1) Infants with uncompromised presentation (UP) who ... |
0 | Cellular mechanisms of multiple myeloma bone disease | MSTS 2018 - Femur Mets and MM | Multiple myeloma (MM) is a hematologic malignancy of differentiated plasma cells that accumulates and proliferates in the bone marrow. MM patients often develop bone disease that results in severe bone pain, osteolytic lesions, and pathologic fractures. These skeletal complications have not only a negative impact on qu... |
0 | Colles fracture, spine fracture, and subsequent risk of hip fracture in men and women. A meta-analysis | Management of Hip Fractures in the Elderly | BACKGROUND: In postmenopausal women, a history of any fracture is an important risk factor for a future hip fracture. Whether similar findings apply to aging men remains to be established. We conducted a systematic review and meta-analysis of the literature to compare men and women with respect to the relative risk of ... |
0 | Platelet rich plasma. A new treatment tool for the rheumatologist? | PRPs for Lateral Epicondylitis/Elbow Tendinopathies | Platelet Rich Plasma (PRP) is a novel therapeutic tool that has revolutionized the world of sports medicine and trauma due to therapeutic success shown in the media. Subject to ongoing debate, the PRP is outlined along a spectrum of musculoskeletal therapies with many qualities that make it ideal for use in the rheumat... |
0 | Coronal Shear Fractures of the Distal Humerus: A Review of Diagnosis, Treatment, and Outcomes | Pediatric Supracondylar Humerus Fracture 2020 Review | Fractures of the capitellum and trochlea are uncommon fractures of the elbow and can be challenging to treat due to their size, location, and articular nature. Because of their intra-articular nature and predilection toward displacement, these fractures are typically treated operatively. Furthermore, capitellum fractur... |
1 | Aggressive rehabilitation following anterior cruciate reconstruction: an update and protocol | Anterior Cruciate Ligament Injuries CPG | Dramatic changes in anterior cruciate ligament (ACL) reconstruction surgery and rehabilitation methods have occurred during the past few years. These developments are reviewed briefly, and a rapid rehabilitation protocol is presented which facilitates the safe return of the patient to his or her pre-operative functiona... |
0 | Diagnostic usefulness of routine nerve conduction studies for the patients with carpal tunnel syndrome | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Background: Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy. There are many additional electrophysiologic methods for diagnosis of CTS. We analyze routine nerve conduction studies to improve diagnostic simplification and sensitivity for CTS. Methods: A total of 70 patients with clinically diagnose... |
0 | The safety and outcome of joint replacement surgery in liver transplant recipients | AAHKS (2) Corticosteroids | A small group of patients may require total hip arthroplasty, total knee arthroplasty, or other joint replacement surgery after OLT for osteoporotic fractures, osteonecrosis, and osteoarthritis. Although arthroplasty is safe in the general population, its safety in liver transplant recipients is unclear. The aim of the... |
0 | Analysis of mechanical factors affecting fixation of olecranon fractures | The Treatment of Pediatric Supracondylar Humerus Fractures AUC | Fractures of the most distal part of the olecranon process differ from more proximal fractures because a plane of instability exists between the humerus and the radial head. Thus, the fixation of these fractures must resist the deforming forces of the forearm flexor muscles. The investigators fixed 10 paired cadaver ul... |
0 | Minimally-invasive plate osteosynthesis in distal tibial fractures: Results and complications | DoD SSI (Surgical Site Infections) | INTRODUCTION: Distal tibial or pilon fractures are usually the result of combined compressive and shear forces, and may result in instability of the metaphysis, with or without articular depression, and injury to the soft tissue. The complexity of injury, lack of muscle cover and poor vascularity make these fractures d... |
0 | Fluoroquinolones in the treatment of Actinobacillus actinomycetemcomitans-associated periodontitis | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | BACKGROUND: Periodontitis patients harboring Actinobacillus actinmycetemcomitans (Aa) are prime candidates for systemic antibiotic therapy. Besides tetracycline and the combination of metronidazole and amoxicillin the fluoroquinolones are also believed to have antibacterial activity against Aa. The aim of the present s... |
0 | The role of positron emission tomography with 18F-fluorodeoxyglucose integrated with computed tomography in the evaluation of patients with multiple myeloma undergoing allogeneic stem cell transplantation | MSTS 2022 - Metastatic Disease of the Humerus | Positron emission tomography (PET) integrated with computed tomography (PET/CT) has been reported to be useful for screening myelomatous lesions at diagnosis in patients with multiple myeloma (MM) and for monitoring response to autologous stem cell transplantation (auto-SCT). The aim of the study was to evaluate the pr... |
0 | NEW FINDINGS FROM MULTIMODAL FUNDUS IMAGING OVER 3 YEARS OF A PATIENT WITH MICROCEPHALY, CHORIORETINOPATHY, AND KIF11 MUTATION | Upper Eyelid and Brow Surgery | PURPOSE: To describe ocular features and long-term follow-up in a patient with microcephaly, chorioretinopathy, and KIF11 mutation. METHODS: Multimodal imaging including fundus color photography, autofluorescence, spectral-domain optical coherence tomography, visual fields, electrophysiologic assessment, and neuroimagi... |
0 | Midterm results of a porous tantalum monoblock tibia component clinical and radiographic results of 108 knees | Surgical Management of Osteoarthritis of the Knee CPG | The use of Trabecular Metal (TM), a biomaterial manufactured from elemental tantalum metal, has recently increased in orthopedics. One hundred eight consecutive TM monoblock tibias were implanted in 95 patients and followed for a minimum of 2 years. The average follow-up was 4.5 years. The average age was 65 years. The... |
0 | Reorganization of equilibrium and movement control strategies after total knee arthroplasty | Surgical Management of Osteoarthritis of the Knee CPG | This work was aimed at identifying changes in posturomotor control strategies in patients with unilateral total knee arthroplasty. Using kinetic and kinematic data, a previous study had revealed that, during a side step, patients with unilateral knee arthritis showed a shortened monopodal phase and a lengthened postura... |
1 | Detection of bacteraemias during non-surgicalroot canal treatment | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | Some dental procedures initiate a bacteraemia. In certain compromised patients, this bacteraemia may lead to distant site infections, most notably infective endocarditis. OBJECTIVE: To investigate whether a detectable bacteraemia was produced during non-surgical root canal therapy. METHODS: Thirty patients receiving no... |
0 | Radiosensitivity of bone metastases from tumors in different primary sites | MSTS 2022 - Metastatic Disease of the Humerus | The purpose of the current clinical trial was to evaluate efficiency of palliative external beam radiotherapy for symptomatic bone metastases from different primary tumors. The randomized study included 427 patients, treated for 616 sites of bone lesions. Breast was the primary site in 67,5% of cases, prostate and lung... |
0 | Improved diagnosis of periprosthetic joint infection by multiplex PCR of sonication fluid from removed implants | PJI DX Updated Search | The microbiological diagnosis of periprosthetic joint infection (PJI) is crucial for successful antimicrobial treatment. Cultures have limited sensitivity, especially in patients receiving antibiotics. We evaluated the value of multiplex PCR for detection of microbial DNA in sonication fluid from removed orthopedic pro... |
0 | Open fractures of the lower limb in Nigeria | DoD SSI (Surgical Site Infections) | During an 18-month period we studied prospectively 63 consecutive patients (42 males, 21 females) with an open fracture of the lower limb. Their mean age was 32 years (range: 4-78 years) and 58 patients with 59 fractures were available until the conclusion of the study. Forty-seven had tibial fractures, 12 had femoral ... |
0 | Subcutaneous inguinal white adipose tissue is responsive to, but dispensable for, the metabolic health benefits of exercise | Panniculectomy & Abdominoplasty CPG | Exercise training has robust effects on subcutaneous inguinal white adipose tissue (iWAT), characterized by a shift to a brown adipose tissue (BAT)-like phenotype. Consistent with this, transplantation of exercise-trained iWAT into sedentary rodents activates thermogenesis and improves glucose homeostasis, suggesting t... |
0 | A comparative prospective clinical study of two single-tooth implants: a preliminary report of 102 implants | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | STATEMENT OF PROBLEM: Treatment of tooth loss in the anterior maxilla can involve difficult functional, esthetic, and psychologic problems, especially in young patients with otherwise good dentition. PURPOSE: The purpose of this study was to provide a preliminary comparative evaluation of two implants (ITI and Astra) i... |
0 | Cell-assisted lipotransfer | Panniculectomy & Abdominoplasty CPG | Adipose tissue is believed to constitute an ideal source of uncultured stromal stem cells. By optimizing the harvesting, storage, and transplantation of adipose tissue, long-lasting results can be obtained. Cell-assisted lipotransfer (CAL) is a novel approach to autologous fat transplantation in which adipose-derived s... |
0 | Multiple epiphyseal dysplasia complicated by severe osteochondritis dissecans of the knee. Incidence in two families | Diagnosis and Treatment of Osteochondritis Dissecans AUC | Two families are described which appear to contain examples of multiple epiphyseal dysplasia. In both families a striking incidence of severe osteochondritis of the knees was encountered. It is suggested that this was caused by the fragmented and maldeveloped epiphyses characteristic of epiphyseal dysplasia |
0 | Functional outcome of en bloc excision and custom prosthetic replacement for giant cell tumor of the distal radius | Distal Radius Fractures | BACKGROUND: Giant cell tumors (GCT) of the distal radius at Campanacci grade II/III are particularly challenging to treat. Wide excision is the management of choice, but this creates a defect at the distal end of radius. We treated 11 cases of GCT of the distal radius by en bloc excision and custom prosthetic replaceme... |
0 | Adductor canal block is similar to femoral nerve block for the quality of rehabilitation after arthroscopic partial meniscectomy | AMP (Acute Meniscal Pathology) | PURPOSE: Adductor canal block (ACB) provides postoperative pain relief as effectively as femoral nerve block (FNB) does, and it preserves the strength of the quadriceps femoris. However, its effect on rehabilitation after arthroscopic partial meniscectomy has not been reported. The purpose of this study was to determin... |
0 | Venous drainage of the femur permits passage of 100-μm particles | MSTS 2018 - Femur Mets and MM | Iatrogenic metastasis of bone tumor is reportedly increased if aggregates of tumor cells enter the circulation. The current study used a previously developed animal model to explore the movement of 25-, 50-, and 100-μm-diameter particles from an experimental femur biopsy site into the circulation. The results indicate... |
0 | The relationship between bone adaptations to resistance exercise and reproductive-hormone levels | Management of Hip Fractures in the Elderly | This study examined the relationships between high-intensity resistance exercise and bone mass in postmenopausal women and serum reproductive-hormone levels and bone-mass changes in response to resistance exercise. Women 45-65 years old were assigned to an exercise or a control group. They trained 3 times weekly for 18... |
0 | Osteonecrosis of the jaws in patients with a history of receiving bisphosphonate therapy: strategies for prevention and early recognition | MSTS 2018 - Femur Mets and MM | BACKGROUND: Bisphosphonates, inhibitors of osteoclasts, have been shown to alleviate many of the devastating consequences associated with metastatic bone disease. However, recent reports have shown that bisphosphonates may cause osteonecrosis of the jaws. Since the publication of these initial reports, the authors have... |
0 | Osteoporotic Fractures in Patients With Atrial Fibrillation Treated With Conventional Versus Direct Anticoagulants | Hip Fx in the Elderly 2019 | BACKGROUND: Elderly patients in long-term treatment with vitamin K antagonists (VKAs) are at high risk of osteoporotic fractures compared with the background population. It has been speculated that the choice of oral anticoagulant (OAC) may affect the risk of osteoporotic fractures.
OBJECTIVES: The risk of osteoporotic... |
0 | Which questionnaire is best? The reliability, validity and ease of use of the patient evaluation measure, the disabilities of the arm, shoulder and hand and the Michigan hand outcome measure | Glenohumeral Joint OA | The Patient Evaluation Measure (PEM), The Michigan Hand Outcome Questionnaire (MHQ) and the Disabilities of the Arm, Shoulder and Hand (DASH) score were assessed independent of their originators for reliability, construct and criterion validity and acceptability, using an ease of use questionnaire. These were administe... |
1 | Reading and reviewing the orthopaedic literature: a systematic, evidence-based medicine approach | Anterior Cruciate Ligament Injuries CPG | The principles of evidence-based medicine are rapidly gaining acceptance in the field of orthopaedic surgery. This approach to patient care requires a careful, systematic review of the literature to appropriately value the merit of studies. Systematic review assists the orthopaedic surgeon in interpreting study results... |
0 | Is non-operative treatment still relevant for Garden Type I fractures in elderly patients? The femoral neck impaction angle as a new CT parameter for determining the indications of non-operative treatment | Hip Fx in the Elderly 2019 | BACKGROUND: The indications of non-operative treatment of undisplaced femoral neck fractures are controversial. The objective of this study was to assess whether two computed tomography (CT) parameters, the femoral neck impaction angle (IA) and the femoral neck posterior tilt angle (PTA), were effective in predicting t... |
1 | Treatment of supracondylar fracture of the humerus (type IIB and III) in children: A prospective randomized controlled trial comparing two methods | The Treatment of Pediatric Supracondylar Humerus Fractures AUC | Background: Consensus on method of treatment of displaced supracondylar fracture of the humerus in children is still lacking. Purpose of this prospective randomized controlled study is to compare closed reduction and long arm slab application with closed reduction and percutaneous crossed Kirschner wires fixation. Mate... |
0 | Distribution of bone density in the proximal femur and its association with hip fracture risk in older men: The osteoporotic fractures in men (MrOS) study | Management of Hip Fractures in the Elderly | This prospective case-cohort study aimed to map the distribution of bone density in the proximal femur and examine its association with hip fracture. We analyzed baseline quantitative computed tomography (QCT) scans in 250 men aged 65 years or older, which comprised a randomly-selected subcohort of 210 men and 40 cases... |
0 | Infection of prosthetic joints | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | Infection of prosthetic joints is one of the most devastating complications following replacement surgery. The size of the problem, the diagnostic puzzle, bacteriological findings and treatment modalities are highlighted |
0 | Early postoperative mortality following joint arthroplasty: A systematic review | SR for PM on OA of All Extremities | Objective. To perform a systematic review of 30- and 90-day mortality rates in patients undergoing hip or knee arthroplasties. Methods. Five databases were searched for English-language studies of mortality in hip or knee arthroplasties and the following data were extracted: patient characteristics (age, sex, ethnicity... |
1 | Near-Infrared Spectroscopy Monitoring for Early Detection of Limb Ischemia in Patients on Veno-Arterial Extracorporeal Membrane Oxygenation | DOD - Acute Comp Syndrome CPG | This study aimed to investigate the effectiveness of near-infrared spectroscopy (NIRS) monitoring for the early detection of limb ischemia in patients who were placed on veno-arterial extracorporeal membrane oxygenation (VA-ECMO) via femoral artery. We prospectively used NIRS monitoring for the early detection of limb ... |
0 | Spiral CT arthrography of the postoperative knee | AMP (Acute Meniscal Pathology) | Computed tomography (CT) has gained multiplanar capability and submillimeter spatial resolution due to the development of spiral acquisition mode and multidetector row technology. Multidetector spiral CT arthrography of the knee is a valuable imaging modality for the assessment of lesions of the meniscus, anterior cruc... |
0 | Use of Magnetic Growing Intramedullary Nails in Compression During Intercalary Allograft Reconstruction | DoD SSI (Surgical Site Infections) | Traditionally, intercalary allograft reconstruction after tumor resection has had a high rate of complications, particularly nonunion. Plate and intramedullary nail fixation have been used alone and in combination to improve union rates. This study sought to evaluate a new technique that uses a magnetic growing intrame... |
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