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The value of tourniquet use for visibility during arthroscopy of the knee: a double-blind, randomized controlled trial
AMP (Acute Meniscal Pathology)
PURPOSE: To study the value of tourniquet use during routine arthroscopy of the knee. METHODS: In this randomized, double-blind controlled trial, 245 patients were included from April 2005 until March 2007 and randomized into an inflated tourniquet group (n = 137) or a deflated tourniquet group (n = 108). The primary o...
1
Posttraumatic stress disorder and depression negatively impact general health status after hand injury
DoD PRF (Psychosocial RF)
PURPOSE: To estimate the prevalence of posttraumatic stress disorder (PTSD) and depression among hand-injured patients and assess the impact of these disorders on general health status. METHODS: A total of 106 adult hand-injured patients (40 women, 66 men) with a mean age of 42 years (range, 18-79 years) participated. ...
1
Platelet-rich plasma (PRP) therapy for knee arthritis: a feasibility study in primary care
PRP (Platelet-Rich Plasma)
Background: Platelet-rich plasma (PRP) is a concentrate of autologous blood growth factors which has been shown to provide some symptomatic relief in early osteoarthritis (OA) of the knee. The objective of this study was to test the feasibility and efficacy potential of platelet rich plasma (PRP) in primary care. Metho...
1
Two-staged breast reconstruction in patients with symptomatic macromastia requiring mastectomy
Reduction Mammoplasty for Female Breast Hypertrophy
Patients with symptomatic macromastia undergoing mastectomy for the treatment of malignant breast disease are candidates for a two-staged operation resulting in breast reconstruction and contralateral breast reduction. Five patients with symptomatic macromastia underwent a skin-sparing mastectomy for breast disease usi...
0
Autologous Adipose-Derived Tissue Matrix Part I: Biologic Characteristics
Panniculectomy & Abdominoplasty CPG
Background: Autologous collagen is an ideal soft tissue filler and may serve as a matrix for stem cell implantation and growth. Procurement of autologous collagen has been limited, though, secondary to a sufficient source. Liposuction is a widely performed and could be a source of autologous collagen. Objectives: The a...
0
Randomized controlled trial of radiographic and patient-assessed outcomes following fixed versus rotating platform total knee arthroplasty
Surgical Management of Osteoarthritis of the Knee CPG
This prospectively blinded randomized controlled study evaluated the difference in the functional and radiological outcomes in patients who received a press-fit condylar Sigma cemented cruciate-substituting total knee arthroplasty with either a rotating platform (RP) or a fixed bearing (FB). There were 51 joints in 49 ...
0
Establishing normal values of the proximal median motor nerve - A study of the pronator teres and flexor carpi radialis in healthy volunteers
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
The importance of normative peripheral nerve data is increasing due to advances in medical implantation, microsurgical suturing, and tubulization repair techniques. Because the median nerve is often affected, its normal values must be reliable. Although the distal portion of the median nerve has been well studied using...
0
Management of bone metastases
MSTS 2018 - Femur Mets and MM
Metastatic bone disease develops as a result of the many interactions between tumor cells and bone cells. This leads to disruption of normal bone metabolism, with the increased osteoclast activity seen in most, if not all, tumor types providing a rational target for treatment. The clinical course of metastatic bone dis...
0
Acquired blepharoptosis
Upper Eyelid and Brow Surgery
A review is given of the aetiology and possible treatment of acquired (non-congenital), blepharoptosis, which is a common but not specific sign of neurological disease. The diagnostic categories of upper eyelid drooping are scheduled as (a) pseudo-ptosis due to a local process or overactivity of eye closure, including ...
0
A laboratory comparison of computer navigation and individualized guides for distal radius osteotomy
Distal Radius Fractures
PURPOSE: This article presents the results of a multiuser, randomized laboratory trial comparing the accuracy and precision of image-based navigation against individualized guides for distal radius osteotomy (DRO). METHODS: Six surgeons each performed four DROs using image-based navigation and four DROs using individua...
0
Impact of degenerative radiographic abnormalities and vertebral fractures on spinal bone density of women with osteoporosis
Management of Hip Fractures in the Elderly
CONTEXT: Measurements of bone density taken by dual-energy x-ray absorptiometry are the most accurate procedure for the diagnosis of osteoporosis. This procedure has the disadvantage of measuring the density of all mineral components, including osteophytes, vascular and extra vertebral calcifications. These alterations...
0
Meniscal repair and regeneration: Current strategies and future perspectives
AMP (Acute Meniscal Pathology)
The management of meniscal injuries remains difficult and challenging. Although several clinical options exist for the treatment of such injuries, complete regeneration of the damaged meniscus has proved difficult due to the limited healing capacity of the tissue. With the advancements in tissue engineering and cell-ba...
0
Bone mineral density, hip axis length and risk of hip fracture in men: results from the Cornwall Hip Fracture Study
Management of Hip Fractures in the Elderly
Bone mineral density (BMD) and hip axis length (HAL) are important determinants of fracture risk in women. There are, however, few data concerning their predictive risk in men. The aim of this study was to determine the relationship between BMD, HAL and the risk of hip fracture in men. A case-control design was used. C...
0
Analgesic control and functional outcome after knee arthroscopy: results of a randomized double-blinded trial comparing a hyaluronic acid supplement with bupivacaine
OAK 3 - Non-arthroplasty tx of OAK
OBJECTIVE: Hyaluronic acid (HA) is a naturally occurring substance within normal synovial joints. Although its efficacy in treating osteoarthritis has been evaluated, it has not been established whether it is of benefit after routine arthroscopic procedures. We hypothesized that immediate supplementation with HA after ...
0
Advances that are changing the diagnosis and treatment of malignant bone tumors
MSTS 2018 - Femur Mets and MM
Purpose of review: Several neoplastic conditions may affect bone. These include primary bone tumors as well as metastatic disease from distant primary sites. Often, these entities produce symptoms that may be difficult to distinguish from those of various rheumatologic entities. The purpose of this review is to discuss...
0
Fracture-separation of the distal humeral epiphysis
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
Fracture-separation of the distal humeral epiphysis presents problems in diagnosis, radiologic interpretation, and management. All of these problems are affected by the arbitrary division of the affected patients into three age groups. Fortunately, although easily misdiagnosed, this fracture does not bear the inherent ...
0
Deficiencies of methods applied in cost effectiveness analysis of hematological malignancies
MSTS 2018 - Femur Mets and MM
Background: As novel therapies in oncology and in particular hematological malignancies impose a high financial burden with a limited increase in life expectancy. Therefore, CEA is important to evaluate the value of new therapies. However, there is a dire need to critically evaluate how valid are such studies. Aims: To...
0
An unusual case of carpal tunnel syndrome
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
A retired middle aged nurse presented with acute bilateral hand pain with associated paraesthesias. She presented to hospital twice, being discharged from ED the first time. Her past medical history was relevant for a two year history of mild carpal tunnel syndrome. On examination she had a maculopapular rash on her tr...
0
Evaluation of an intervention to change benzodiazepine-prescribing behavior in a prepaid group practice setting
Management of Hip Fractures in the Elderly
To determine the effect of two levels of educational intervention on benzodiazepine-prescribing behavior in an elderly population in a controlled prepaid group practice (PPGP) setting, we designed a prospective controlled trial, with six-month follow-up. Our setting was a 270,000 member group- model PPGP in Colorado, f...
0
Transfemoral amputee recovery strategies following trips to their sound and prosthesis sides throughout swing phase
DoD LSA (Limb Salvage vs Amputation)
BACKGROUND: Recovering from trips is challenging for transfemoral amputees, and attempts often result in falls. Better understanding of the effects of the sensory-motor deficits brought by amputation and the functional limitations of prosthetic devices could help guide therapy and fall prevention mechanisms in prosthes...
0
Therapeutic embolization of the genicular arteries for recurrent hemarthrosis after total knee arthroplasty
Surgical Management of Osteoarthritis of the Knee CPG
The case of a recurrent hemarthrosis initially presenting 30 months after a total knee arthroplasty in a patient on lifelong warfarin is described. Angiography was used to aid in the diagnosis, and therapeutic selective embolization of the superior genicular arteries was performed with satisfactory clinical results
0
Expression and potential role of chemokine receptor CXCR4 in human bladder carcinoma cell lines with different metastatic ability
MSTS 2018 - Femur Mets and MM
The aim of the present study was to investigate the expression of the chemokine receptor CXCR4 in human bladder carcinoma cells and its possible role in their metastatic growth in vitro. Immunofluorescent imaging and flow cytometry were performed to examine the expression of CXCR4 in the EJ and EJ-M3 cell lines. A high...
1
Peripheral nerve entrapments, repetitive strain disorder, occupation-related syndromes, bursitis, and tendonitis
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Physiologically, peripheral nerve entrapments show focal slowing, and histologically, segmental demyelination and remyelination occur. Entrapment neuropathies result from direct mechanical injury (eg, chronic low pressure or friction in the carpal tunnel syndrome). Compartment syndromes occur when locally increased pre...
1
Distal radius fractures--systematic review
Distal Radius Fractures
Distal radius fractures are an increasingly prevalent upper extremity injury, especially among elderly patients. They represent approximately 3% of all upper extremity injures. Severity of these fractures is directly related to bone mineral density of the patient, and clinical results are dependent on this parameter as...
0
The radiological and clinical follow-up of osteonecrosis in cancer patients
Pediatric Diaphyseal Femur Fractures 2020 Review
BACKGROUND: In patients with cancer, osteonecrosis (ON) lesions can affect multiple sites throughout the skeleton, including the long and short bones and the joints. The aims of this study were to explore the natural course of ON in patients treated for cancer by using radiological classification suitable for multisite...
0
Tourniquetless Total Knee Arthroplasty With Modern Perioperative Protocols Decreases Pain and Opioid Consumption in Women
AAHKS (4) Acetaminophen
BACKGROUND: This study examined whether a modern total knee arthroplasty (TKA) protocol without a tourniquet results in less patient-reported pain and in-hospital opioid consumption compared to TKA with a tourniquet. METHODS: A retrospective study of 203 primary unilateral cemented TKAs consecutively performed with or ...
0
Preserving the neurovascular supply in the Hall-Findlay superomedial pedicle breast reduction: an anatomical study
Reduction Mammoplasty for Female Breast Hypertrophy
Background: The Hall-Findlay superomedial pedicle technique is widely used for breast reduction, and, despite low complication rates, nipple-areola complex (NAC) necrosis and denervation are still the two most common complications, particularly when resection volumes exceed 600 g. An understanding of the anatomy of the...
1
Preoperative planning and postoperative imaging in shoulder arthroplasty
Glenohumeral Joint OA
The number of shoulder arthroplasties performed in the United States has more than doubled in the last decade. Additionally, there has been a trend toward use of reverse total shoulder arthroplasty and minimally invasive surgical techniques, such as resurfacing humeral head arthroplasty. Thus radiologists will more fre...
0
Metastatic angiosarcomas: Doxorubicin-based regimens, weekly paclitaxel and metastasectomy significantly improve the outcome
MSTS 2022 - Metastatic Disease of the Humerus
Background: Angiosarcomas are a rare but aggressive form of soft tissue sarcoma. At metastatic stage, the clinical benefit of therapeutic intervention remains debatable. Patients and methods: We have carried a retrospective analysis of 149 cases treated between 1996 and 2009 in the French Sarcoma Group. Results: The me...
0
Diabetes is associated with persistent pain after hip and knee replacement
OAK 3 - Non-arthroplasty tx of OAK
Background and purpose-In some patients, for unknown reasons pain persists after joint replacement, especially in the knee. We determined the prevalence of persistent pain following primary hip or knee replacement and its association with disorders of glucose metabolism, metabolic syndrome (MetS), and obesity.Patients ...
0
Epidemiologic and survival trends in adult primary bone tumors of the spine
MSTS 2022 - Metastatic Disease of the Humerus
BACKGROUND CONTEXT: Malignant primary spinal tumors are rare making it difficult to perform large studies comparing epidemiologic, survival, and treatment trends. We investigated the largest registry of primary bone tumors, the National Cancer Database (NCDB), to compare epidemiologic and survival trends among these tu...
0
Clinical and MRI outcomes of HA injection following arthroscopic microfracture for osteochondral lesions of the talus
Osteochondritis Dissecans 2020 Review
PURPOSE: The purpose of this study was to compare the clinical and magnetic resonance imaging (MRI) outcomes of arthroscopic microfracture surgery alone or in combination with hyaluronic acid (HA) injection in the treatment of osteochondral lesions of the talus. METHODS: Thirty�five patients with osteochondral lesion...
0
Perioperative clopidogrel and postoperative events after hip and knee arthroplasties
PJI DX Updated Search
BACKGROUND: Hip and knee arthroplasties are widely performed and vascular disease among patients having these procedures is common. Clopidogrel is a platelet inhibitor that decreases the likelihood of thrombosis. It may cause intraoperative and postoperative bleeding, but its discontinuation increases the risk of vascu...
0
The effect of delayed treatment on clinical and radiological effects of anterior wedge grafting for non-union of scaphoid fractures
Distal Radius Fractures
INTRODUCTION: The aim of the treatment of displaced scaphoid non-unions is the restoration of normal scaphoid anatomy. Restoration of normal scaphoid anatomy at an earlier stage might have functional benefits as maladaptive carpal ligament contractures and the development of preliminary osteoarthritis could be avoided....
0
Current concepts in pathophysiology and diagnosis of compartment syndromes
DoD - ACS - Interrater Reliability
A compartment syndrome is a neurovascular compromise resulting from an increased local tissue pressure. Compartment syndromes can have many etiologies and may arise in any area of the body that has little or no capacity for tissue expansion. The sequelae are severe in the absence of immediate diagnosis and treatment. T...
0
Long-term results of 56 revision total knee replacements
Surgical Management of Osteoarthritis of the Knee CPG
Fifty-six consecutive revised total knee arthroplasties (TKA) were followed for an average of 8.3 years (range: 3 to 15 years). The purpose of this study was to evaluate the results of revision TKA to determine any trends in either the good outcomes or the failures. We found that the success rate for revision TKA was c...
0
Conscious sedation and reduction of fractures in the paediatric population: an orthopaedic perspective
Distal Radius Fractures
Purpose: Closed reduction under conscious sedation in the emergency department (ED) has been demonstrated to provide cost-effective, timely care. There has been little research into the efficacy of conscious sedation and reduction from an orthopaedic trauma perspective. This study describes the epidemiology and outcome...
0
Neuromuscular exercise (NEMEX-TJR) improves knee extension muscle power and chair stands ability in patients with severe knee osteoarthritis compared to controls: A randomized controlled trial
Surgical Management of Osteoarthritis of the Knee CPG
Purpose: Knowledge on effects of exercise in patients with severe and end-stage OA is sparse. The purpose was to evaluate the effect of a neuromuscular exercise program (NEMEX-TJR) on objective functional performance and muscle power in patients with severe knee OA. Methods: Design. Randomized controlled trial (NCT0100...
0
Autologous Platelet Rich Plasma (PRP) in the treatment of elbow epicondylitis and plantar fasciitis: medium to long term clinical outcome
PRPs for Lateral Epicondylitis/Elbow Tendinopathies
BACKGROUND AND AIM: Platelet-Rich-Plasma (PRP) is a popular biological therapy especially used to regenerate different musculoskeletal tissues by releasing growth-factors and cytokines promoting cell proliferation, chemotaxis, differentiation, and angiogenesis. The aim was to evaluate the clinical effectiveness and saf...
0
Evaluation of Nutritional Status and Correlation with Postoperative Complications in Elderly Patients Submitted to Surgical Treatment of Proximal Femoral Fractures
Hip Fx in the Elderly 2019
<b>Objective</b> This study aims to evaluate and correlate the nutritional status with potential complications during the immediate postoperative period of elderly patients surgically treated for proximal femoral fractures. <b>Methods</b> A prospective, cross-sectional analytical study with a quantitative approach, tar...
0
The microbiology of the infected knee arthroplasty
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
We describe the results of a retrospective analysis of patients with microbiologically proven infection, who underwent revision TKA between 1994 and 2008. Of the 121 patients included in the study, 61 (50%) were male and 60 (50%) were female. The mean age was 71 (range 42-88) years. The most common organisms identified...
0
Gigantomastia and Macroprolactinemia Responding to Cabergoline Treatment: A Case Report and Minireview of the Literature
Reduction Mammoplasty for Female Breast Hypertrophy
Background. Macroprolactinemia is defined as predominance of high molecular weight prolactin forms in the circulation. Although macroprolactin is considered as a biologically inactive molecule, some authorities suggest treatment in symptomatic cases. Gigantomastia is defined as excess breast tissue and most cases in th...
0
Is radiographic measurement of bony landmarks reliable for lateral meniscal sizing?
Surgical Management of Osteoarthritis of the Knee CPG
BACKGROUND: The accuracy of meniscal measurement methods is still in debate. HYPOTHESIS: The authors' protocol for radiologic measurements will provide reproducible bony landmarks, and this measurement method of the lateral tibial plateau will correlate with the actual anatomic value. STUDY DESIGN: Controlled laborator...
0
Endoscopic compartment release for chronic exertional compartment syndrome: surgical technique and results
DOD - Acute Comp Syndrome CPG
BACKGROUND: Chronic exertional compartment syndrome is an entity that typically fails nonoperative management and requires operative treatment with fasciotomies for return to activity. Fasciotomies performed through single or multiple incisions may fail to totally release the fascia of the afflicted compartment(s) and ...
0
Frontalis sling surgery: A treatment modality for cyclic oculomotor nerve palsy
Upper Eyelid and Brow Surgery
Cyclic oculomotor nerve paresis and spasm are a rare disorder characterized by alternating spastic and paretic phase of the muscles supplied by the oculomotor nerve. A 26-year-old male presented with abnormal right eyelid movements since early childhood. Examination findings were consistent with diagnosis of right eye ...
0
Symptomatic multifocal osteonecrosis: A multicenter study
AAHKS (2) Corticosteroids
Osteonecrosis of the femoral head frequently occurs in a young population (mean age, approximately 35 years) and may lead to disabling arthritis requiring hip arthroplasty surgery. This disease is compounded when it has concurrent involvement of other joints. Multifocal osteonecrosis is defined as disease involving thr...
0
Post-traumatic stress disorder symptoms may explain poor mental health in patients with fibromyalgia
DoD PRF (Psychosocial RF)
Symptoms of post-traumatic stress disorder are common in fibromyalgia patients. This study compared post-traumatic stress disorder symptoms in fibromyalgia patients and healthy controls and determined whether patient-control differences in post-traumatic stress disorder symptoms mediated differences in mental health. I...
0
Minimally invasive harvesting of nonvascularized fibular graft in children
DoD SSI (Surgical Site Infections)
Using a nonvascularized fibular graft is part of the therapeutic arsenal for filling bone loss defects. It is conventionally performed by open surgery. The authors propose a minimally invasive technique for harvesting a free fibular graft. The fibula was removed subperiosteally by two or three small incisions in five p...
0
Altered tibiofemoral joint contact mechanics and kinematics in patients with knee osteoarthritis and episodic complaints of joint instability
OAK 3 - Non-arthroplasty tx of OAK
BACKGROUND: To evaluate knee joint contact mechanics and kinematics during the loading response phase of downhill gait in knee osteoarthritis patients with self-reported instability. METHODS: Forty-three subjects, 11 with medial compartment knee osteoarthritis and self-reported instability (unstable), 7 with medial com...
0
Cardiovascular safety of the cyclooxygenase-2 selective inhibitors parecoxib and valdecoxib in the postoperative setting: An analysis of integrated data
AAHKS (8) Anesthetic Infiltration
BACKGROUND:: Studies of parecoxib, the inactive prodrug of the cyclooxygenase-2 selective inhibitor valdecoxib, and valdecoxib for postoperative pain relief in patients undergoing coronary artery bypass graft surgery revealed an increased risk of cardiovascular (CV) adverse events compared with placebo. We conducted th...
0
Acupuncture in the treatment of lateral epicondilitis: Evaluation of the effectiveness and comparison with ultrasound therapy
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
The lateral epicondilitis, known as 'tennis elbow', is a frequent disease in people playing manual sports or jobs. The most common treatments are based on physical or pharmacological therapies, but the disease often relapses or becomes chronic. We decided to try acupuncture, that does not bring the side effects of the ...
0
Kashin Beck Disease: more than just osteoarthrosis: a cross-sectional study regarding the influence of body function-structures and activities on level of participation
Glenohumeral Joint OA
The purpose of this study was to investigate the influence of body function, activities and pain on the level of activity in adults with Kashin Beck Disease (KBD). Seventy-five KBD patients with a mean age of 54.8 years (SD 11.3) participated. Anthropometrics, range of joint motion (ROM) and muscle strength were measur...
0
Manipulation of pediatric supracondylar fractures of humerus in prone position under general anesthesia
DoD SSI (Surgical Site Infections)
BACKGROUND:: Displaced pediatric supracondylar fractures are usually treated with manipulation and fixation with Kirschner wires. The procedure is commonly performed with the patient in supine position. Reducing and stabilizing the fracture with the patient in supine position are associated with various risks and techn...
0
Patients with black hip and black knee due to ochronotic arthropathy: Case report and review of literature
Surgical Management of Osteoarthritis of the Knee CPG
Ochronotic arthropathy is a manifestation of longstanding alkaptonuria. With increasing age, an accumulation of pigment deposits of homogentisic acid in the joint cartilage results in ochronotic osteoarthritis. We present a case of a 62-year-old female who underwent staged left uncemented total hip and right cemented t...
0
Management of patients with prosthetic heart valves during non-cardiac surgery
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
Non-cardiac surgery in patients with prosthetic heart valves poses the particular hazards of infective endocarditis, increased bleeding risk and the possibility of acute/subacute valve thrombosis or systemic thromboembolism associated with interrupted anticoagulation. Management is complicated by the absence of randomi...
0
Hand-injured patients' experiences of cold sensitivity and the consequences and adaptation for daily life: a qualitative study
DoD PRF (Psychosocial RF)
STUDY DESIGN: Qualitative descriptive. INTRODUCTION: Cold sensitivity is a common and persistent complaint after hand injuries. PURPOSE OF THE STUDY: To explore the experiences of severe cold sensitivity, its consequences for daily life, and the strategies for enduring and enabling occupation. METHODS: Fifteen hand-inj...
0
Reconstruction plate versus minimal invasive retrograde titanium elastic nail fixation for displaced midclavicular fractures
DoD SSI (Surgical Site Infections)
BACKGROUND: Nonoperative management of midshaft clavicle fractures (MSCFs) is standard; however, it is now generally accepted that displaced midshaft clavicle fractures benefit from internal fixation. Plating and intramedullary fixation have become the accepted methods of fixation. The purpose of this study was to see ...
1
A 1-Year Follow-Up of Post-operative Scars After the Use of a 1210-nm Laser-Assisted Skin Healing (LASH) Technology: A Randomized Controlled Trial
Reduction Mammoplasty for Female Breast Hypertrophy
BACKGROUND: Laser therapies are used prophylactically for excessive scar formation. The Laser-Assisted Skin Healing treatment induces a controlled heat stress that promotes tissue regeneration. This comparative trial is the first to evaluate the performance of a new automated 1210-nm laser system, compatible with all F...
0
Unintended effects of orphan product designation for rare neurological diseases
MSTS 2018 - Femur Mets and MM
Since the introduction of the Orphan Drug Act in 1983, designed to promote development of treatments for rare diseases, at least 378 orphan drugs have been approved. Incentives include financial support, tax credits, and perhaps most importantly, extended market exclusivity. These incentives have encouraged industry in...
0
Injection of Adipose-Derived Stromal Cells in the Knee of Patients with Severe Osteoarthritis has a Systemic Effect and Promotes an Anti-Inflammatory Phenotype of Circulating Immune Cells
OAK 3 - Non-arthroplasty tx of OAK
<b>Rationale:</b> Recent studies confirmed that osteoarthritis (OA) is associated with systemic inflammation. Adipose-derived stromal cells (ASCs) could become the most promising cell-based therapy in OA, based not only on their differentiation capacities and trophic and paracrine effects on the existing cartilage, but...
1
Arthroscopy--"no-problem surgery". An analysis of complications in two thousand six hundred and forty cases
AMP (Acute Meniscal Pathology)
In a retrospective review of 3,261 arthroscopic procedures on the knee, 2,640 met the criteria for inclusion in this analysis. The patients' ages ranged from eight to eighty-three years. There were 1,541 male and 1,099 female patients. Eight hundred and ninety-five of the injuries were work-related. A tourniquet was us...
0
Pediatric femoral shaft fractures treated by flexible intramedullary nailing
DoD SSI (Surgical Site Infections)
Background Nowadays pediatric femoral fractures are more commonly managed with operative treatment rather than conservative treatment because of more rapid recovery and avoidance of prolonged immobilization. Children between the ages of 5-13 years are treated either by traction plus hip spica and flexible/elastic stabl...
0
Effect of Osteosarcopenia on Postoperative Functional Outcomes and Subsequent Fracture in Elderly Hip Fracture Patients
Hip Fx in the Elderly 2019
Introduction: In this study, we evaluated how muscle mass and bone density affect postoperative functional scores and subsequent fracture rates and investigated the correlation between sarcopenia and osteoporosis by measuring preoperative psoas muscle indices (PMIs) and bone mineral densities (BMDs) in elderly patients...
0
Treatment of acetabulum fractures through the modified Stoppa approach: strategies and outcomes
PJI DX Updated Search
BACKGROUND: Since the original description by Letournel in 1961, the ilioinguinal approach has remained the predominant approach for anterior acetabular fixation. However, modifications of the original abdominal approach described by Stoppa have made another option available for reduction and fixation of pelvic and ace...
0
Effects of platelet-derived growth factor, vitamin D and parathyroid hormone on osteoblasts derived from cancer patients on chronic bisphosphonate therapy
MSTS 2018 - Femur Mets and MM
Bisphosphonates consist of a family of pyrophosphate analogues that are currently being used to treat metastatic bone diseases as well as systemic bone diseases such as osteoporosis. There is accumulating evidence suggesting that patients treated with these bisphosphonates can develop, particularly with invasive dental...
0
Clinical results of alumina medial pivot total knee arthroplasty at a minimum follow-up of 10 years
DoD SSI (Surgical Site Infections)
Background The medial pivot total knee prosthesis with alumina ceramic femoral components was introduced to reproduce physiological knee kinematics and reduce polyethylene wear. The five-year clinical outcomes of alumina medial pivot total knee arthroplasties (TKA) have previously been reported. The purpose of this stu...
0
Clinical outcomes of corrective osteotomy for distal radial malunion: a review of opening and closing-wedge techniques
Distal Radius Fractures
BACKGROUND: Radial corrective osteotomy is an established but challenging treatment for distal radial malunion. There is ongoing discussion over whether an opening or closing-wedge osteotomy should be employed. The purpose of the present study was to retrospectively compare the clinical and radiographic results of conv...
0
Quality of life in patients with skeletal metastases of prostate cancer and status prior to start of endocrine therapy: results from the Scandinavian Prostate Cancer Group Study 5
MSTS 2022 - Metastatic Disease of the Humerus
OBJECTIVES: Prostate cancer (PC) is a highly lethal neoplastic disease affecting the physical, mental and social well-being of patients, i.e. their quality of life (QOL). Patients suffering from metastatic PC are faced with serious decisions regarding treatment strategies. Therefore, QOL information has become a crucia...
0
Association of tumor molecular factors with in-transit metastasis in primary cutaneous melanoma
MSTS 2022 - Metastatic Disease of the Humerus
BACKGROUND: In-transit metastases (ITM) are a form of locoregional relapse representing intralymphatic metastatic spread and occur in approximately 4-9% of patients with melanoma >1 mm Breslow thickness. Our objective was to evaluate a combination of clinicopathologic risk factors and gene expression biomarkers predict...
0
In patients undergoing fast track total knee arthroplasty, addition of buprenorphine to a femoral nerve block has no clinical advantage
AAHKS (2) Corticosteroids
Background: Several adjuvants have been proposed to prolong the effect of peripheral nerve blocks, one of which is buprenorphine. In this randomized double blinded placebo controlled trial we studied whether the addition of buprenorphine to a femoral nerve block prolongs analgesia in patients undergoing total knee arth...
0
Lactase persistence-related genetic variant: Population substructure and health outcomes
Management of Hip Fractures in the Elderly
Lactase persistence is an autosomal-dominant trait that is common in European-derived populations. A basic tendency for lactase persistence to increase from the southeast to the northwest across European populations has been noted, but such trends within countries have not been extensively studied. We genotyped the C/T...
0
Thromboembolic events in children and young adults with pediatric sarcoma
MSTS 2022 - Metastatic Disease of the Humerus
PURPOSE: Adults with malignancy are at increased risk for venous thromboembolic events (TEs). However, data in children and young adults with cancer are limited. PATIENTS AND METHODS: To determine the risk and clinical features of TEs in children and young adults with sarcoma, we reviewed records on 122 consecutive pat...
0
Hemophagocytic lymphohistiocytosis in a neonate with cutis marmorata telangiectatica congenita
Patrick’s pharmacoepidemiology project
In this case report we describe the first case of hemophagocytic lymphohistiocytosis with concurrent cutis marmorata telangiectatica congenita. She had pancytopenia and hepatosplenomegaly, hemophagocytic cells in spleen necropsy, and she died with respiratory failure and pseudomonas induced septicemia
0
A study to compare the presence of virulence factors gelatinase, haemolysin, enterococcal surface protein (esp) and biofilm formation among clinical and commensal isolates of enterococcus species
DoD SSI (Surgical Site Infections)
Enterococci are responsible for serious diseases such as urinary tract infections (cystitis, urethritis, pyelonephritis and prostatis), bacteremia, intra-abdominal, pelvic and soft tissue infections. Infection on burn surfaces were also commonly caused by Enterococcus. The ability of enterococci to cause such diseases ...
0
Treatment of osteochondritis dissecans of the knee
Osteochondritis Dissecans 2020 Review
Successful treatment of osteochrondritis dissecans lesions with long-term preservation of the articular cartilage is a challenging problem. The appropriate treatment for an individual lesion depends on several factors, including stability of the lesion and the skeletal maturity of the patient. In this article, we revie...
1
The role of microvascular free flaps in salvaging below-knee amputation stumps: a review of 22 cases
DoD LSA (Limb Salvage vs Amputation)
Twenty-two cases of traumatic below-knee amputation stumps with inadequate soft-tissue coverage salvaged with microvascular free flaps were reviewed retrospectively. All patients would have required an above-knee amputation for prosthesis fitting had microvascular free flaps not bee utilized. A total of 24 flaps were u...
0
Prevention and treatment of osteoporosis
Management of Hip Fractures in the Elderly
Osteoporosis develops in older adults when the normal processes of bone formation and resorption become uncoupled or unbalanced, resulting in bone loss. Fractures are the result of decreased bone mass and strength and, in the case of wrist and hip fractures, usually involve a fall. Osteoporosis prevention and treatment...
0
Comparison of the results of bilateral total knee arthroplasty with and without patellar replacement for rheumatoid arthritis
Surgical Management of Osteoarthritis of the Knee CPG
Simultaneous bilateral total knee arthroplasty was performed in twenty- six patients who had rheumatoid arthritis, and a patellar replacement was performed concurrently in one randomly selected knee in each patient. A lateral retinacular release was performed in all knees. The patients were followed for at least six ye...
0
Multiplanar reformation computed tomogram is better than MR imaging in decision making for apparently isolated fractures of the greater trochanter
Hip Fx in the Elderly 2019
OBJECTIVES: We evaluated isolated fractures of the greater trochanter (IFGT) on plain radiographs with multiplanar reformation computed tomography (MPR CT). DESIGN: Retrospective review of patients. SETTING: University teaching hospital. PATIENTS: This study included 27 consecutive patients with apparently IFGT. MAIN O...
0
Bisphosphonate effects on the behaviour of oral epithelial cells and oral fibroblasts
MSTS 2018 - Femur Mets and MM
OBJECTIVE: Bisphosphonates (BPs) like Zometa (ZA) are widely used to treat complications of bony metastases in cancer patients. A serious adverse event occurs in 1-12% of patients on BP therapy, osteonecrosis of the jaw (BPONJ). BPONJ develops after oral trauma and is manifested by poor wound healing and soft-tissue br...
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MRI efficacy in diagnosing internal lesions of the knee: a retrospective analysis
AMP (Acute Meniscal Pathology)
BACKGROUND: Many surgeons tend to believe that MRI is an accurate, non invasive diagnostic method, enough to lead to decisions for conservative treatment and save a patient from unnecessary arthroscopy. We conducted a retrospective study to investigate the accuracy of the MRI of the knee for the detection of injuries o...
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Late synovial enhancement detects effects of intraarticular steroids on synovitis better than synovial volume
OAK Recommendation 9 Articles
Purpose: Previous work has shown that synovial tissue shrinks in response to an intra-articular steroid injection and this volume reduction might be used to measure the effect of treatments targeting synovitis in knee osteoarthritis (OA). While synovial volume reduction is seen on static post-contrast MRI scans, dynami...
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A method for determining median nerve conduction velocity across the carpal tunnel
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Palmar stimulation was used to assess median nerve conduction across the carpal tunnel. In 50 hands from 25 control subjects, motor and sensory latencies in the wrist-to-palm segment (mean +/- SD: 1.15 +/- 0.21 msec and 1.12 +/- 0.21 msec respectively) were less than half the conventional terminal latencies in the wris...
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Comparison of highly cross-linked and conventional polyethylene in posterior cruciate-substituting total knee arthroplasty in the same patients
PJI DX Updated Search
BACKGROUND: We are not aware of any information on in vivo clinical results at a minimum of five years after posterior cruciate-substituting total knee arthroplasties performed with a highly cross-linked polyethylene insert. The purpose of the study was to evaluate whether the clinical and radiographic results of poste...
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Local steroid injection or carpal tunnel release for carpal tunnel syndrome - Which is more effective?
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Objective: To compare the effectiveness of local steroid injection (LSI) and carpal tunnel release (CTR) operation for the treatment of carpal tunnel syndrome (CTS). Methodology: This is a prospective randomized clinical trial conducted at Khalifa Gul Nawaz Teaching Hospital and District Headquarters Teaching Hospital,...
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Prosthetic joint infection after total hip or knee arthroplasty in rheumatoid arthritis patients treated with nonbiologic and biologic disease-modifying antirheumatic drugs
AAHKS (2) Corticosteroids
The aim of this study was to identify risk factors for acute surgical-site infection (SSI) after total joint arthroplasty in rheumatoid arthritis (RA) patients treated with nonbiologic and biologic disease-modifying antirheumatic drugs (DMARDs). We performed a retrospective study of all consecutive total hip (THA) and ...
1
Evaluation of Osseous Incorporation After Osteochondral Allograft Transplantation: Correlation of Computed Tomography Parameters With Patient-Reported Outcomes
Osteochondritis Dissecans 2020 Review
BACKGROUND: Studies have reported favorable clinical outcomes after osteochondral allograft (OCA) transplantation to treat osteochondral defects and have demonstrated that healing of the osseous component may be critical to outcomes. However, there is currently no consensus on the optimal modality to evaluate osseous h...
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Reconstruction of bone defects with impacted allograft in femoral stem revision surgery
Management of Hip Fractures in the Elderly
A retrospective clinical review was done on 54 revision hip patients. Radiological analysis examined the Gross and AAOS classifications, stem position, cement mantles, allograft and evolution (subsidence, resorption and remodelling). The Harris Hip score was used for clinical assessment. We used bone bank allograft and...
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The Portsmouth modification of the Ertl bone-bridge transtibial amputation: The challenge of returning amputees back to active duty
DoD LSA (Limb Salvage vs Amputation)
In the military setting, severe lower-extremity trauma is an unfortunate but not uncommon result of armed conflict. Newer body armor has lead to an increase in survival as a result of the protection afforded the head, abdomen, and thorax. However, the extremities are still relatively unprotected, resulting in an increa...
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Hematoma Block for Distal Radius Fracture
Distal Radius Fractures
Hematoma blocks are safe and effective in providing analgesia for fracture reduction1�4. They involve injecting lidocaine directly into the fracture line for analgesia. The physician aspirates blood prior to injection to confirm placement in the hematoma created by the fracture. However, the procedure can be technica...
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Knee reconstruction with preservation of the meniscus in tibial giant cell tumor
AMP (Acute Meniscal Pathology)
UNLABELLED: Giant cell tumor of bone sometimes is an aggressive benign skeletal tumor. Historically, curettage and bone grafting have a high recurrence with satisfactory function whereas wide resection has a reduced recurrence rate with compromise of limb function. Thus, maintaining joint function and achieving adequat...
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Operation or Plaster in Wrist Fractures
Distal Radius Fractures
INTERVENTION: Open reduction and internal plate fixation versus plaster immobilisation CONDITION: Wrist fracture, Radius ; ; PRIMARY OUTCOME: PRWE SECONDARY OUTCOME: DASH, SF36, VAS, ROM, grip strength, radiographic outcomes, costâ?effectiveness and costâ?utility INCLUSION CRITERIA: â?¢ Patients from 18 â?? 65 years ...
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Derangement of knee: Role of radionuclide imaging in the diagnosis
Diagnosis and Treatment of Osteochondritis Dissecans AUC
Bone scintigraphy in diagnosis of knee derangements is a very useful investigation. From its inception, bone scintigram has developed into a reliable tool with advancing technologies of both hardware and software. The bone scintigraphy is not widely performed though it can be very rewarding especially in diagnosing kne...
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The natural history of the hemiarthroplasty for displaced intracapsular femoral neck fractures
HipFx Supplemental Cost Analysis
Background Numerous papers have been published on the medium- and long-term results of hemiarthroplasties (HAs) after femoral neck fracture in the elderly. We were not aware of any articles that describe the outcome of HA until the patient dies. Methods Between 1975 and 1989, 307 bipolar hemiarthroplasties were perform...
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Loosening of the porous coating of bicompartmental prostheses in patients with rheumatoid arthritis
Surgical Management of Osteoarthritis of the Knee CPG
Thirty-four porous-coated anatomical (PCA) total knee arthroplasties in twenty-eight patients with rheumatoid arthritis were followed for an average of seventeen months. In these thirty-four knees, twenty-three tibial and fifteen femoral components were cemented. The rest were uncemented. At follow-up, more than half o...
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A randomized prospective controlled trial of antibiotic prophylaxis in intraoral bone grafting procedures: single-dose clindamycin versus 24-hour clindamycin prophylaxis
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
PURPOSE: The objective of this study was to compare the efficacy of a single oral dose of clindamycin with a 24-h protocol of clindamycin administration in local buccal onlay grafting procedures. MATERIAL AND METHODS: A prospective randomized study in 124 patients was performed. Eligible patients were randomized to rec...
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The use of uncemented extensively porous-coated femoral components in the management of Vancouver B2 and B3 periprosthetic femoral fractures
Management of Hip Fractures in the Elderly
We assessed the outcome of patients with Vancouver type B2 and B3 periprosthetic fractures treated with femoral revision using an uncemented extensively porous-coated implant. A retrospective clinical and radiographic assessment of 22 patients with a mean follow-up of 33.7 months was performed. The mean time from the i...
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HFE C282Y homozygosity is associated with an increased risk of total hip replacement for osteoarthritis
Surgical Management of Osteoarthritis of the Knee CPG
OBJECTIVE: The evidence for an association between mutations in the HFE (hemochromatosis) gene and the risk of hip or knee osteoarthritis is inconsistent. Total joint replacement is considered a surrogate measure for symptomatic end-stage osteoarthritis. We examined the relationship between HFE gene mutations and risk ...
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Life course analysis as a behavioural modifier for oral health
DoD PRF (Psychosocial RF)
For an individual to survive in the nature, health is the primary requirement. This health has many determinants, one of which is sound health behaviour, which if modified to a positive path can assist in acquiring a sound health. The new widely accepted theory to modify this health behaviour to achieve sound health is...
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Mechanisms for distal motor nerve conduction slowing in amyotrophic lateral sclerosis
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
The aim of this study was to elucidate the frequency of the prolongation of distal motor latency (DML) in the median nerve and its mechanisms in patients with amyotrophic lateral sclerosis (ALS). We measured the DMLs, compound muscle action potentials (CMAP) and nerve conduction velocities in 73 consecutive patients wi...