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0 | Association between cartilage and bone biomarkers and incidence of radiographic knee osteoarthritis (RKOA) in UK females: a prospective study | OAK 3 - Non-arthroplasty tx of OAK | OBJECTIVE: There is a need to find biochemical markers that would identify people with increased risk of developing radiographic knee osteoarthritis (RKOA). The aim of this study was to evaluate the ability of cartilage and bone biomarkers (cartilage oligomeric matrix protein (COMP), aggrecan, cellular inhibitor of apo... |
0 | Associations between the chemokine biomarker CCL2 and knee osteoarthritis outcomes: the Johnston County Osteoarthritis Project | OAK 3 - Non-arthroplasty tx of OAK | Objective: Our study analyzes the association between chemokine-ligand-2 (CCL2) serum concentrations at baseline and knee radiographic osteoarthritis (OA) (knee-rOA), knee-rOA progression, individual radiographic features and knee symptomatic OA at 5-year follow-up. Design: OA outcomes were analyzed in a community-base... |
0 | Quantitative Magnetic Resonance Imaging UTE-T2 Mapping of Cartilage and Meniscus Healing After Anatomic Anterior Cruciate Ligament Reconstruction | AMP (Acute Meniscal Pathology) | BACKGROUND: An anterior cruciate ligament (ACL) injury greatly increases the risk for premature knee osteoarthritis (OA). Improved diagnosis and staging of early disease are needed to develop strategies to delay or prevent disabling OA.
PURPOSE: Novel magnetic resonance imaging (MRI) ultrashort echo time (UTE)-T2(*) ma... |
0 | Septic arthritis update | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | (bullet) The most common pathogenesis of septic arthritis is bacteremic seeding. (bullet) In the evaluation of a patient with acute monoarthritis, think sepsis first. (bullet) Once septic arthritis is suspected and cultures are performed, antibiotic treatment should begin immediately. (bullet) The cost-effectiveness of... |
1 | Pain and function in eight hundred and fifty nine patients comparing shoulder hemiprostheses, resurfacing prostheses, reversed total and conventional total prostheses | Glenohumeral Joint OA | PURPOSE: Functional results of reversed total prostheses (RTP) have-to a very limited degree-been compared with those of other shoulder prosthesis types. The aim of our study was to compare results of four different types of shoulder prostheses in terms of function, pain, and quality of life (QoL).
METHODS: Questionnai... |
1 | Use of Saline as a Placebo in Intra-articular Injections in Osteoarthritis: Potential Contributions to Nociceptive Pain Relief | OAK 3 - Non-arthroplasty tx of OAK | BACKGROUND: Osteoarthritis of the knee (OAK) is a severe debilitating condition characterized by joint pain, stiffness, and resultant limited mobility. In recent years, intra-articular (IA) injections have been used to relieve symptoms and have succeeded to varying degrees either with sodium hyaluronate preparations or... |
0 | Obesity and the absence of trochlear dysplasia increase the risk of revision in patellofemoral arthroplasty | OAK 3 - Non-arthroplasty tx of OAK | Purpose: Proper indications and patient selection are of paramount importance in patellofemoral arthroplasty (PFA). Although factors predicting outcomes in total knee arthroplasty (TKA) have been studied, there are no such studies for modern PFA. This retrospective study reports the midterm clinical and radiological ou... |
0 | Impact of broad regulatory regions on Gdf5 expression and function in knee development and susceptibility to osteoarthritis | AMP (Acute Meniscal Pathology) | OBJECTIVES: Given the role of growth and differentiation factor 5 (GDF5) in knee development and osteoarthritis risk, we sought to characterise knee defects resulting from Gdf5 loss of function and how its regulatory regions control knee formation and morphology. METHODS: The brachypodism (bp) mouse line, which harbour... |
0 | Are myofibroblasts activated in idiopathic carpal tunnel syndrome? an immunohistochemical study | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | OBJECTIVES: This study aims to investigate whether myofibroblasts participate in the fibrotic process of idiopathic carpal tunnel syndrome (CTS). PATIENTS AND METHODS: Forty patients (12 males, 28 females; median age 50.85 +/- 11.2 years; range 30 to 71 years) who were operated in our clinic between March 2010 and Augu... |
0 | Management of benign bone tumours | Osteochondritis Dissecans 2020 Review | Benign bone tumours are rare, occurring most commonly in skeletally immature patients, and usually arising from cartilage or bone. The commonest locations are the distal femur, proximal tibia and proximal humerus. They present with pain, swelling or pathological fracture. Diagnosis is by plain radiographs, MRI and core... |
0 | Serum retinyl esters are not elevated in postmenopausal women with and without osteoporosis whose preformed vitamin A intakes are high | Management of Hip Fractures in the Elderly | BACKGROUND: Recent observational studies suggest that preformed vitamin A (VA) intakes of 1500-2000 microg/d may increase the risk of osteoporosis and hip fracture. However, few studies have examined associations between biologic indicators of VA and osteoporosis. OBJECTIVE: This study characterized VA intake, serum VA... |
1 | Postoperative analgesia after knee surgery: A comparison of three different concentrations of ropivacaine for continuous femoral nerve blockade | AAHKS (9/10) Regional Nerve Blocks | BACKGROUND: The most effective ropivacaine concentration for femoral infusion after total knee arthroplasty is currently ill defined. We designed the present study to compare ropivacaine in three different concentrations (0.1, 0.2, and 0.3%) to evaluate analgesic quality, when administered as a continuous infusion with... |
1 | Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis | OAK 3 - Non-arthroplasty tx of OAK | OBJECTIVE: To investigate the efficacy and safety of dietary supplements for patients with osteoarthritis.
DESIGN: An intervention systematic review with random effects meta-analysis and meta-regression.
DATA SOURCES: MEDLINE, EMBASE, Cochrane Register of Controlled Trials, Allied and Complementary Medicine and Cumulat... |
0 | Pain Control After Total Knee Arthroplasty: is There Benefit In Adding Single Shot Adductor Canal Block to Existing Multimodal Pain Regimen and Periarticular Injection Protocol? | AAHKS (9/10) Regional Nerve Blocks | The purpose of this project is to compare the effectiveness of two different but well accepted approaches to nerve blockade in order to improve pain control after total knee arthroplasty. Specifically, this study seeks to identify the if adductor canal blockade provides additional pain relief and decreased morphine con... |
0 | Effect of adductor canal block versus femoral nerve block on quadriceps strength, mobilization, and pain after total knee arthroplasty: A randomized, blinded study | AAHKS (8) Anesthetic Infiltration | Background and Objectives: Total knee arthroplasty (TKA) is often associated with severe pain. Different regional anesthetic techniques exist, all with varying degrees of motor blockade. We hypothesized that pain relief provided by the adductor canal block (ACB) could increase functional muscle strength. Methods: We in... |
0 | Determinants of functional outcome after simple and complex acetabular fractures involving the posterior wall | Management of Hip Fractures in the Elderly | We have evaluated the functional, clinical and radiological outcome of patients with simple and complex acetabular fractures involving the posterior wall, and identified factors associated with an adverse outcome. We reviewed 128 patients treated operatively for a fracture involving the posterior wall of the acetabulum... |
0 | The validity of using administrative claims data in total joint arthroplasty outcomes research | PJI DX Updated Search | The purpose of this study was to evaluate concordance between administrative and clinical diagnosis and procedure codes for revision total joint arthroplasty (TJA). Concordance between administrative and clinical records was determined for 764 consecutive revision TJA procedures from 4 hospitals. For revision total hip... |
0 | Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data | OAK 3 - Non-arthroplasty tx of OAK | Osteoarthritis is the most common musculoskeletal disease and the leading cause of disability globally. Here, we performed a genome-wide association study for osteoarthritis (77,052 cases and 378,169 controls), analyzing four phenotypes: knee osteoarthritis, hip osteoarthritis, knee and/or hip osteoarthritis, and any o... |
0 | Environmental disruption of circadian rhythm predisposes mice to osteoarthritis-like changes in knee joint | OAK 3 - Non-arthroplasty tx of OAK | Circadian rhythm dysfunction is linked to many diseases, yet pathophysiological roles in articular cartilage homeostasis and degenerative joint disease including osteoarthritis (OA) remains to be investigated in vivo. Here, we tested whether environmental or genetic disruption of circadian homeostasis predisposes to OA... |
0 | Lateralizing epidural catheter placement as evidenced by electrical stimulation | AAHKS (8) Anesthetic Infiltration | BACKGROUND: Epidural steroids are more effective if administered in the anterolateral epidural space. It follows that the ability to administer local anesthetics in the ipsilateral anterolateral epidural space should likewise improve their efficacy for postoperative epidural analgesia.
QUESTIONS/PURPOSES: We determined... |
0 | Osteoarthritis year in review 2016: mechanics | AMP (Acute Meniscal Pathology) | Inappropriate biomechanics, namely wear-and-tear, has been long believed to be a main cause of osteoarthritis (OA). However, this view is now being re-evaluated, especially when examined alongside mechanobiology and new biomechanical studies. These are multiscale experimental and computational studies focussing on cell... |
0 | HIF-1alpha dysfunction in diabetes | DoD LSA (Limb Salvage vs Amputation) | Diabetic wounds are a significant public health burden, with slow or nonhealing diabetic foot ulcers representing the leading cause of non-traumatic lower limb amputation in developed countries. These wounds heal poorly as a result of compromised blood vessel formation in response to ischemia. We have recently shown th... |
0 | Cost of Surgical Treatment for Distal Radius Fractures and the Implications of Episode-Based Bundled Payments | Distal Radius Fractures | PURPOSE: To examine the cost of care of surgical treatment for a distal radius fracture (DRF) and develop episodes that may be used to develop future bundled payment programs.
METHODS: Using 2009 to 2015 claims data from the Truven MarketScan Databases, we examined the cost of care for surgical treatment of DRFs among ... |
0 | Mechanisms of action of bisphosphonates in oncology: a scientific concept evolving from antiresorptive to anticancer activities | MSTS 2018 - Femur Mets and MM | Bisphosphonates are approved for treating malignant bone disease from advanced cancer because they are effective inhibitors of osteoclast-mediated bone resorption. However, there may be a greater role for the use of bisphosphonates than has previously been considered. There is a large body of preclinical evidence showi... |
0 | The Dexamethasone for Pain Treatment After Total Knee Arthroplasty Trial | AAHKS (4) Acetaminophen | Trial name: Dexamethasone twice for pain treatment of total knee arthroplasty: A randomised, blinded, pragmatic, 3â?group multicentre clinical trial Trial Acronym: DEXâ?2â?TKA Background: Effective postoperative pain management is essential for the wellâ?being and rehabilitation of the surgical patient. No "gold st... |
0 | Mindfulness is associated with psychological health and moderates pain in knee osteoarthritis | OAK 3 - Non-arthroplasty tx of OAK | OBJECTIVE: Previous studies suggest that higher mindfulness is associated with less pain and depression. However, the role of mindfulness has never been studied in knee osteoarthritis (OA). We evaluate the relationships between mindfulness and pain, psychological symptoms, and quality of life in knee OA.
METHOD: We per... |
0 | The feasibility of a progressive twelve-week neuromuscular and strength training program in middle-aged patients with degenerative meniscus tears | AMP (Acute Meniscal Pathology) | Purpose: To describe the feasibility of a progressive twelve-week neuromuscular and strength training program in middle-aged patients with degenerative meniscus tear by the use of a single case report. Feasibility was determined as 1) acceptable self-reported pain during the program, 2) decreased pain throughout the pr... |
0 | Transplanted Senescent Cells Induce an Osteoarthritis-Like Condition in Mice | OAK 3 - Non-arthroplasty tx of OAK | Osteoarthritis (OA) is the leading form of arthritis in the elderly, causing pain, disability, and immobility. OA has been associated with accumulation of senescent cells in or near joints. However, evidence for a causal link between OA and cellular senescence is lacking. Here, we present a novel senescent cell transpl... |
0 | The Relationship between Chondromalacia Patella, Medial Meniscal Tear and Medial Periarticular Bursitis in Patients with Osteoarthritis | AMP (Acute Meniscal Pathology) | BACKGROUND: This study investigated the presence of bursitis in the medial compartment of the knee (pes anserine, semimembranosus-tibial collateral ligament, and medial collateral ligament bursa) in osteoarthritis, chondromalacia patella and medial meniscal tears.
PATIENTS AND METHODS: Radiological findings of 100 pati... |
1 | Endoscopic carpal tunnel release | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | We have performed 149 consecutive one-portal and 152 consecutive two-portal endoscopic carpal tunnel release operations. Average time to cessation of preoperative symptoms was 15 days in both the one-portal and two-portal groups. The average time of return to work was 16 days in the one-portal group and 17 days in the ... |
0 | Lean business model and implementation of a geriatric fracture center | Hip Fx in the Elderly 2019 | Geriatric hip fracture is a common event associated with high costs of care and often with suboptimal outcomes for the patients. Ideally, a new care model to manage geriatric hip fractures would address both quality and safety of patient care as well as the need for reduced costs of care. The geriatric fracture center ... |
0 | Vertical Tears of the Lateral Meniscus: Effects on In Vitro Tibiofemoral Joint Mechanics | OAK 3 - Non-arthroplasty tx of OAK | BACKGROUND: Lateral meniscal tears are often seen with acute anterior cruciate ligament (ACL) injury and may be left in situ, repaired, or treated with meniscectomy. Clinical studies have shown good outcomes with vertical tears left in situ and poor outcomes following meniscectomy. However, clinically relevant studies ... |
0 | Internal fixation of intracapsular hip fractures with a dynamic locking plate: initial experience and results for 83 patients treated with a new implant | Management of Hip Fractures in the Elderly | The results of treatment for 83 patients treated with a new implant designed specifically for the internal fixation of intracapsular hip fractures are reported. Nonunion occurred in one out of the 37 undisplaced fractures (3%) and seven out of the 46 displaced fractures (15%). In addition, four patients developed avasc... |
1 | The impact of a civic service program on biopsychosocial outcomes of post 9/11 U.S. military veterans | DoD PRF (Psychosocial RF) | Volunteering as a health promotion intervention, improves physical health, mental health, and social outcomes particularly in older adults, yet limited research exists for veterans. We conducted a preliminary study to explore whether volunteering impacts a variety of biopsychosocial outcomes, including symptoms of post... |
0 | Management of the chronic irreducible patellar dislocation in total knee arthroplasty | Surgical Management of Osteoarthritis of the Knee CPG | Neglected dislocation of the patella with gonarthrosis, genu valgum, flexion, and external rotation deformity is rarely encountered. Experience with five total knee arthroplasties in three patients with chronic patellar dislocation and gonarthrosis is reported. All knees had a modified proximal patellar realignment and... |
0 | The extended-short nail system, a novel concept in the management of proximal femur fractures | Management of Hip Fractures in the Elderly | In light of recent health care reform and the aging US Medicare population, it is becoming increasingly important for orthopedic surgeons to use effective and efficient strategies for hip fracture surgery. The Extended-Short Nail System (ES nail) is a US Food and Drug Administration-approved titanium nail which is lock... |
0 | Immediate breast reconstruction - A review of indications, techniques and results | Reduction Mammoplasty for Female Breast Hypertrophy | Background: It has only been during the last decade that immediate breast reconstruction has become accepted as an integrated part of the treatment concept of breast cancer in Austria. The involvement of the plastic surgeon in the planning of treatment at the time of the diagnosis of breast cancer is still far from sta... |
1 | Bilateral lower-extremity amputation wounds are associated with distinct local and systemic cytokine response | DoD LSA (Limb Salvage vs Amputation) | BACKGROUND: Approximately 25% of U.S. military members sustaining extremity amputations in recent military conflicts have bilateral lower-extremity amputations (BLA). We investigated among combat-related extremity wounds whether BLA exhibit different bacterial burden, inflammatory response, and local complications. MET... |
0 | Anabolic steroids for rehabilitation after hip fracture in older people | Hip Fx: Early-Weight Bearing Search | Background: Hip fracture occurs predominantly in older people, many of whom are frail and undernourished. After hip fracture surgery and rehabilitation, most patients experience a decline in mobility and function. Anabolic steroids, the synthetic derivatives of the male hormone testosterone, have been used in combinati... |
0 | Factors predisposing to dislocation after primary total hip arthroplasty: A multivariate analysis | Management of Hip Fractures in the Elderly | We conducted this study to determine the relative influence of various mechanical and patient-related factors on the incidence of dislocation after primary total hip asthroplasty (THA). Of 2,023 THAs, 21 patients who had at least 1 dislocation were compared with a control group of 21 patients without dislocation, match... |
0 | Opioid users show worse baseline knee osteoarthritis and faster progression of degenerative changes: a retrospective case-control study based on data from the Osteoarthritis Initiative (OAI) | AMP (Acute Meniscal Pathology) | BACKGROUND: Opioids are frequently prescribed for pain control in knee osteoarthritis patients, despite recommendations by current guidelines. Previous studies have investigated the chondrotoxicity of different opioid subtypes. However, the impact opioids may have on progression of osteoarthritis in vivo remains unknow... |
0 | Surgical management principles of gunshot-related fractures | DOD - Acute Comp Syndrome CPG | This article discusses contemporary management strategies for gunshot-related fractures with special attention paid to the initial evaluation, role of debridement, principles of fixation, need and duration of antibiotic therapy, and management of sequelae. Pertinent sequelae detailed are fractures associated with vascu... |
0 | A randomised controlled trial of Tai Chi and resistance exercise on bone health, muscle strength and balance in community-living elderly people | Management of Hip Fractures in the Elderly | BACKGROUND: The beneficial role of exercise in improving bone mineral density, muscle strength and balance, has been documented predominantly in younger populations. These findings may not apply to elderly populations with limited ability to perform exercises of high intensity.OBJECTIVE: To examine the effects of Tai C... |
0 | Effectiveness and cost-effectiveness of outpatient physiotherapy after knee replacement for osteoarthritis: Study protocol for a randomised controlled trial | OAK 3 - Non-arthroplasty tx of OAK | Background: Primary total knee replacement is a common operation that is performed to provide pain relief and restore functional ability. Inpatient physiotherapy is routinely provided after surgery to enhance recovery prior to hospital discharge. However, international variation exists in the provision of outpatient ph... |
1 | Single-bundle anterior cruciate ligament reconstruction in active young men using bone-tendon achilles allograft versus free tendon achilles allograft | Anterior Cruciate Ligament Injuries CPG | PURPOSE: The purpose was to prospectively compare the outcomes of anterior cruciate ligament (ACL) reconstruction using bone-tendon Achilles allograft with those of free tendon Achilles allograft in 2 groups of active young men. METHODS: We enrolled 72 subjects in the study. Of these, 33 subjects who had ACL reconstruc... |
0 | Thirty-day Outcomes After Surgery for Metastatic Bone Disease of the Extremities: An Analysis of the NSQIP Database | DoD SSI (Surgical Site Infections) | INTRODUCTION: Metastatic bone disease of the extremities is a notable cause of morbidity and mortality. Surgical management is not curative; therefore, risks and benefits of surgery must be carefully considered. Previous studies of surgical outcomes are limited by small sample sizes because of the rare incidence of the... |
0 | Antibiotic prohylaxis in urologic prosthetic surgery | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | The implantation of prosthetic devices is an ever-increasing practice in urologic surgery. The most common devices are penile prostheses, artificial urinary sphincters, synthetic pubovaginal slings, and bone anchors used for pelvic floor reconstruction and incontinence surgery. While their efficacy has been supported o... |
1 | The effect of meniscal tears on cartilage loss of the knee: findings on serial MRIs | AMP (Acute Meniscal Pathology) | BACKGROUND: The relationship between meniscal tears and progressive loss of hyaline cartilage and osteoarthritis of the knee has been reported in the literature. The current treatment protocols for meniscal tears include conservative treatment, meniscal repair, and meniscectomy. Treatment plans are based on factors suc... |
0 | Elevated blood urea, independent of glomerular filtration rate (GFR), confers increased risk of adverse functional outcome in elderly hip fracture patients | Management of Hip Fractures in the Elderly | This retrospective cohort study investigated the possible interrelations of GFR and functional outcome in elderly hip fracture patients. The final analyses comprised 499 consecutive patients undergoing standard medical, surgical and rehabilitation treatment in an orthogeriatric unit of a tertiary care hospital. Functio... |
0 | Surgical management of the middle age arthritic knee | Surgical Management of Osteoarthritis of the Knee CPG | There are several options available for management of the middle-aged arthritic knee. Arthroscopic techniques continue to evolve, but the true natural history of the arthritic process is probably not altered. Good to excellent short-term results can be expected with proper patient selection. Patient counseling is impor... |
0 | Incidence of hip fractures in Jeju Island, South Korea: a prospective study (2002-2006) | Management of Hip Fractures in the Elderly | BACKGROUND: This study was performed to estimate the incidence of hip fractures of people older than 50 years in South Korea. METHODS: Information of patients over 50 years of age who had sustained a hip fracture were obtained from the records of eight hospitals in Jeju Island between 2002 and 2006 to calculate the inc... |
0 | Flexion contracture can be relieved by concurrent notchplasty in medial open wedge high tibial osteotomy | AMP (Acute Meniscal Pathology) | BACKGROUND: Given that medial open wedge high tibial osteotomy (OWHTO) not only delays the progression of osteoarthritis but also alleviates the resulting pain, surgical outcomes would be improved if limited ROM can also be managed. In this regard, the effect of concurrent notchplasty on flexion contracture has not bee... |
0 | Infective endocarditis | Dental Implant Infection | Infective endocarditis is a serious disease of the endocardium of the heart and cardiac valves, caused by a variety of infectious agents, ranging from streptococci to rickettsia. The proportion of cases associated with rheumatic valvulopathy and dental surgery has decreased in recent years, while endocarditis associate... |
0 | Label free process monitoring of 3D bioprinted engineered constructs via dielectric impedance spectroscopy | AMP (Acute Meniscal Pathology) | Biofabrication processes can affect biological quality attributes of encapsulated cells within constructs. Currently, assessment of the fabricated constructs is performed offline by subjecting the constructs to destructive assays that require staining and sectioning. This drawback limits the translation of biofabricati... |
1 | Lateral closed wedge osteotomy for cubitus varus deformity | The Treatment of Pediatric Supracondylar Humerus Fractures AUC | BACKGROUND: Lateral closed wedge (LCW) osteotomy is a commonly accepted method for the correction of the cubitus varus deformity. The fixation of osteotomy is required to prevent loss of correction achieved. The fixation of the osteotomy by the two screw and figure of eight wire is not stable enough to maintain the cor... |
1 | Efficacy and Safety of Platelet-Rich Plasma Injections for Osteoarthritis | PRP (Platelet-Rich Plasma) | Purpose of the review: Therapeutic options for the treatment of osteoarthritis (OA), the most common type of arthritis, are limited, leaving many patients symptomatic and resulting in extensive disability and economic cost. Platelet-rich plasma (PRP) has become a therapeutic treatment offered by a number of practitione... |
0 | Second metatarsophalangeal joint: biomechanics and reconstruction potential | Distal Radius Fractures | A damaged distal radioulnar joint results in instability, pain, and loss of motion. This amounts to function loss. Of the many proposed reconstructive procedures, only a vascularized joint transfer offers growth potential in children and durability. The well-studied vascular anatomy and minimal donor morbidity of the s... |
0 | Ipsilateral inflammatory neuropathy after hip surgery | PJI DX Updated Search | OBJECTIVE: To identify whether new ipsilateral weakness after hip surgery may be due to an inflammatory as opposed to a mechanical process. PATIENTS AND METHODS: Seven patients (8 hip surgeries) seen between July 1, 2008, and June 30, 2011, developed unexplained ipsilateral leg weakness and pain within 1 month of hip s... |
0 | Point-of-care ultrasound in the diagnosis of upper extremity fracture-dislocation: A pictorial essay | Pediatric Supracondylar Humerus Fracture 2020 Review | Patients commonly present with orthopedic injuries to the emergency department (ED). Although radiographs are the standard of care for evaulating these injuries, point-of-care ultrasound is being increasingly used to make the diagnosis. This modality can be useful in patients who are too clinically unstable to leave th... |
0 | Total hip arthroplasty in Japanese patients with ankylosing spondylitis | PJI DX Updated Search | The purpose of this study was to examine the postoperative results following THA for ankylosing spondylitis, which is very rare in Japanese. We performed uncemented THA in 31 hips between 1982 and 2007. Patients were followed up for a mean of 12 years. The 10-year survival rate was 100%, and the 15-year survival rate w... |
0 | Caution should be used in long-term treatment with oral compounds of hyaluronic acid in patients with a history of cancer | OAK 3 - Non-arthroplasty tx of OAK | Intra-articular administration of hyaluronic acid is a valuable therapeutic tool for the management of patients with osteoarthritis. However, in recent years numerous formulations containing hyaluronic acid administrable by oral route have entered the market. Even if there are some data in the literature that have show... |
0 | Loop diuretic use and increased rates of hip bone loss in older men: the Osteoporotic Fractures in Men Study | Management of Hip Fractures in the Elderly | BACKGROUND: Older adults commonly use loop diuretics, which can increase urinary calcium excretion, leading to potential bone loss. Studies examining the association between loop diuretics and bone mineral density (BMD) are lacking, particularly those involving men. METHODS: In this cohort study, we ascertained medicat... |
0 | Men versus women: does size matter in total knee arthroplasty? | Surgical Management of Osteoarthritis of the Knee CPG | The role played by femoral component sizing in the clinical outcome of primary TKA is currently debated. Oversizing the femur in patients with smaller knees could lead to overstuffing the knee capsule with resulting pain and reduced range of motion. We asked whether the distribution of femoral component sizes differed ... |
0 | Expression of ras p21, p53 and c-erbB-2 in advanced breast cancer and response to first line hormonal therapy | MSTS 2018 - Femur Mets and MM | Several oncogenes and tumour-suppressor genes have been identified that may have an important role in the development of human breast carcinoma. Furthermore, some of these gene alterations may be linked to the development of invasion and subsequent metastasis. Alterations in the expression of ras p21, p53 and c-erbB-2 ... |
1 | Repeated electrophysiologic studies in patients with carpal tunnel syndrome following local corticosteroid injection using a novel approach | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | BACKGROUND: Local corticosteroid injection (LCI) for the treatment of carpal tunnel syndrome (CTS), using the classic method, is usually associated with improvement in different electrophysiologic parameters of the median nerve. However, there is no correlation between the clinical response and these electrophysiologic... |
0 | Group C streptococcal infection in a prosthetic joint | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | We present possibly the first reported case of prosthetic joint infection due to group C Streptococcus in a 53-year-old man. The patient was treated with surgical debridement along with extended intravenous antibiotics and long-term oral penicillin therapy. He was able to retain the prosthesis and at 4-year follow-up h... |
0 | Clinical and MRI evaluation of medium- to long-term results after autologous osteochondral transplantation (OCT) in the knee joint | OAK 3 - Non-arthroplasty tx of OAK | PURPOSE: Autologous osteochondral transplantation (OCT) is one of the surgical options currently used to treat cartilage defects. It is the only cartilage repair method that leads to a transfer of hyaline cartilage repair tissue. The purpose of this study was to evaluate the magnetic resonance observation of cartilage ... |
0 | Safety of total hip arthroplasty for femoral neck fractures using the direct anterior approach: A retrospective observational study in 86 elderly patients | PJI DX Updated Search | Background: The femoral neck fracture is one of the most common fractures in the elderly. A variety of methods and approaches are used to treat it. Total hip arthroplasty is a preferred approach in independent, mobile, elderly patients, given its more favorable long-term outcome. Our hypothesis is that the direct anter... |
0 | Fracture prevalence in an Australian population | Management of Hip Fractures in the Elderly | There is little published information on the epidemiology of fracture in Australia. We have therefore carried out a population-based retrospective study of fracture in an Australian population covering 1,073 subjects, 60 per cent of the eligible population over the age of 65 resident in Busselton in the southwest of We... |
0 | Thiazolidinediones and fractures: evidence from translating research into action for diabetes | DoD LSA (Limb Salvage vs Amputation) | BACKGROUND: Thiazolidinedione (TZD) treatment has been associated with fractures. The purpose of this study was to examine the association between TZD treatment and fractures in type 2 diabetic patients. METHODS: Using data from Translating Research into Action for Diabetes, a multicenter prospective observational stud... |
0 | Cartilage oligomeric matrix protein in serum and synovial fluid of rheumatoid arthritis: potential use as a marker for joint cartilage damage | Surgical Management of Osteoarthritis of the Knee CPG | This study examined the serum and synovial fluid concentrations of cartilage oligomeric matrix protein (COMP) in relation to the evolution of joint cartilage damage and the requirement for surgery in 125 patients with rheumatoid arthritis (RA). We compared the erythrocyte sedimentation rate (ESR), C-reactive protein (C... |
0 | Dental implants in children: A multidisciplinary perspective for long-term success | DoD PRF (Psychosocial RF) | Congenital hypodontia or trauma is a frequent cause of loss of teeth in children. The absence of teeth leads to loss of function and lack of normal alveolar growth, along with unpleasant esthetics that hamper the psychosocial development of the young child. Traditionally, the management of tooth loss in the young child... |
0 | Micromastia vs. macromastia | Reduction Mammoplasty for Female Breast Hypertrophy | There is little doubt that in our bosom conscious culture a woman needs to have enough (or would like to have enough). More than enough breast may also be desirable, if it can be shaped and positioned attractively. When the breasts are too large to be attractive, or their support and control become difficult, or when s... |
0 | Treatment of medial compartment arthritis of the knee: a survey of the American Association of Hip and Knee Surgeons | Surgical Management of Osteoarthritis of the Knee CPG | Medial compartmental arthritis of the knee is a common orthopedic problem. This study surveyed active members of the American Association of Hip and Knee Surgeons on recommended surgical treatment of this condition. A response rate of 30.8% was obtained. One third of respondents (32.9%) reported patient age as the most... |
0 | Standard and emerging therapies for metastatic differentiated thyroid cancer | MSTS 2018 - Femur Mets and MM | Differentiated thyroid cancer accounts for >90% of cases of thyroid cancer, with most patients having an excellent prognosis. Distant metastases occur in 10%-15% of patients, decreasing the overall 10-year survival rate in this group to 40%. Radioactive iodine has been the mainstay of treatment for distant metastases, ... |
0 | Changes in impairment and function after static progressive splinting for stiffness after distal radius fracture | Distal Radius Fractures | The purpose of this study was to describe changes in range of motion, grip strength, and function in subjects treated with static progressive splinting for stiffness after distal radius fracture. A retrospective review was conducted on 25 patients; outcomes reviewed included wrist/forearm motion, grip strength and Disa... |
0 | The Prevalence of Meniscal Pathology in Asymptomatic Athletes | AMP (Acute Meniscal Pathology) | BACKGROUND: Meniscal pathology is a commonly seen orthopedic condition that can affect a wide age range of patients. Athletes subject their menisci to an increased amount of stress during their careers and may increase their risk of meniscal pathology.
OBJECTIVE: The purpose of this systematic review is to evaluate the... |
0 | Current Trends in the Evaluation and Management of Nondisplaced Femoral Neck Fractures in the Elderly | Hip Fx in the Elderly 2019 | Nondisplaced (Garden I and II) femoral neck (FN) fractures are commonly encountered by the practicing orthopaedic surgeon. Although these fractures are primarily classified based on the AP radiograph, the lateral radiograph should be closely scrutinized as well because posterior tilt has emerged as a consistent predict... |
0 | The menacing phantom: what pulls the trigger? | DoD LSA (Limb Salvage vs Amputation) | Phantom phenomena are frequent following amputation, but how this often painful experience is modified or triggered by spontaneous events or sensations often puzzles amputees and clinicians alike. We explored triggers of phantom phenomena in a heterogeneous sample of 264 upper and lower limb adult amputees with phantom... |
1 | Efficacy of Electro-acupuncture Versus Manual Acupuncture on Knee Osteoarthritis | OAK 3 - Non-arthroplasty tx of OAK | Participants will be randomly allocated to one of two groups. Those in the first group receive electroâ?acupuncture, which involves having needles inserted into acupuncture points (locations on the body affected by acupuncture) which are stimulated manually for 10 seconds to create "De Qi" sensation and an electrical ... |
0 | Trajectories of functional decline in knee osteoarthritis: The osteoarthritis initiative | OAK 3 - Non-arthroplasty tx of OAK | Objective. To describe trajectories of functional decline over 84 months and study associated risk factors among adults initially without limitation who had or were at risk of knee OA. Methods. We used annual measures of WOMAC physical function over 84 months from the OA Initiative. We included knees with no functional... |
0 | Non-operative treatment options for knee osteoarthritis: Current concepts | PRP (Platelet-Rich Plasma) | Knee osteoarthritis in younger patients can be a challenging condition to manage. The patient and clinician have a range of non-operative management options available, although the guidance to effectively apply these options is lacking. The following review summarises a range of non-operative treatment options as an ac... |
0 | Evaluation of Midterm Clinical and Radiographic Outcomes of Arthroscopically Repaired Vertical Longitudinal and Bucket-Handle Lateral Meniscal Tears | AMP (Acute Meniscal Pathology) | BACKGROUND: Lateral meniscal tears in the stable knee are rare. There are few comparative studies evaluating functional and radiological outcomes of vertical longitudinal and bucket-handle lateral meniscal tears.
PURPOSE: To evaluate the midterm clinical and radiological outcomes of arthroscopically repaired traumatic ... |
0 | A one-stop approach to the management of soft tissue and degenerative musculoskeletal conditions using clinic-based ultrasonography | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | BACKGROUND AND OBJECTIVE: One-stop clinics aim at assessment, investigation and initiating treatment in a single hospital visit. They have been proven to be cost-effective and to increase patient satisfaction in various specialties. The aim of this study was to describe the one-stop approach to managing soft tissue and... |
0 | Femoral neck and intertrochanteric fractures have different risk factors: a prospective study | Management of Hip Fractures in the Elderly | The aim of this study was to determine whether both types of hip fracture, femoral neck and intertrochanteric, have similar risk factors. A prospective cohort study was carried out on community-dwelling elderly women in four areas of the United States: Baltimore, MD; Pittsburgh, PA; Minneapolis, MN and Portland, OR. Th... |
0 | Skin preparation before hip replacement in emergency setting versus elective scheduled arthroplasty: bacteriological comparative analysis | DoD SSI (Surgical Site Infections) | INTRODUCTION: Hip arthroplasty needs to be performed in an emergency setting after intracapsular femur neck fracture, whereas pain makes preoperative skin preparation of the limb difficult and it may therefore be incomplete. To date no study has analyzed the patient's skin bacteriological status in these surgical condi... |
0 | Skateboarding injuries in Vienna: Location, frequency, and severity | DoD PRF (Psychosocial RF) | Objective: To describe injury patterns of skateboard-associated injuries (SAIs) and to assess the frequency and severity of SAIs depending on an athlete's skateboarding experience. Design: Cross-sectional observation. Setting: Skating areas. Participants: A total of 100 Viennese skateboarders. Interventions: No interve... |
0 | Femoral neck collapse after internal fixation of an intracapsular hip fracture: Does it indicate a poor outcome? | Hip Fx in the Elderly 2019 | The degree of femoral neck collapse that occurred after 519 patients with an intracapsular hip fracture treated by internal fixation with a Targon FN implant was measured. Mean femoral neck collapse was 8.0mm and this was increased for displaced fractures in comparison to undisplaced fractures (9.5mm versus 5.9mm, p<0.... |
1 | Arthroscopic meniscus repair for recurrent subluxation of the lateral meniscus | AMP (Acute Meniscal Pathology) | PURPOSE: This study was undertaken to diagnose and to document the clinical results and technical aspects of arthroscopic meniscus repair for recurrent subluxation with peripheral tears around the popliteal hiatus of the lateral meniscus.
METHODS: Twenty-three patients (24 knees) with symptomatic recurrent subluxation ... |
1 | A suture "retractor": a technical aid for bucket-handle meniscal resections | AMP (Acute Meniscal Pathology) | Meniscal repair, healing, and survival have been demonstrated in the literature. Meniscal preservation is, however, not always possible. We present a technique that may aid the surgeon in difficult bucket handle resections by stabilizing a portion of the meniscus with a "suture retractor" prior to resecting either a po... |
0 | Incidence, risk factors and case fatality rate for hip fracture in Chile: A cross-sectional study based on 2017 national registries | Hip Fx in the Elderly 2019 | Purpose: To describe the incidence of hip fracture in Chile during 2017, identify risk factors for in-hospital mortality, and estimate annual case fatality rate.
Method: The study design was cross-sectional and analytical. We obtained the registries of all patients from the Chilean Ministry of Health who were treated f... |
0 | Kidney disease associated with plasma cell dyscrasias | MSTS 2018 - Femur Mets and MM | Plasma cell dyscrasias are frequently encountered malignancies often associated with kidney disease through the production of monoclonal immunoglobulin (Ig). Paraproteins can cause a remarkably diverse set of pathologic patterns in the kidney and recent progress has been made in explaining the molecular mechanisms of p... |
0 | Gastrointestinal complications in the intensive care unit | DOD - Acute Comp Syndrome CPG | Pathologic conditions affecting the abdomen are a significant cause of morbidity and mortality in the intensive care unit, but their importance is not widely recognized. This article presents several aspects of abdominal pathology that can occur in intensive care unit patients. This pathology may have a considerable im... |
0 | Risk factors for fear of falling in elderly patients with severe knee osteoarthritis before and one year after total knee arthroplasty | OAK 3 - Non-arthroplasty tx of OAK | Purpose. To evaluate the regression of fear of falling (FOF) and identify its risk factors in patients with severe knee osteoarthritis before and one year after total knee arthroplasty (TKA). Methods. 11 men and 57 women with a mean age of 73 years and a mean body mass index of 30.36 kg/m2 who had severe (grade 3 or 4)... |
0 | Distal humerus lateral condyle fracture in children: when is the conservative treatment a valid option? | The Treatment of Pediatric Supracondylar Humerus Fractures AUC | INTRODUCTION: Distal humerus condyle fracture in children is rare. These fractures often mislead the emergency physician or surgeon. However, treatment adapted to the degree of displacement achieves excellent clinical and radiographic results. The objective of this study was to clarify indications for conservative trea... |
1 | Unconstrained shoulder arthroplasty | Glenohumeral Joint OA | OBJECTIVE : To evaluate the results of 36 unconstrained shoulder arthroplasties. |
0 | Total knee arthroplasty on the disease activity of rheumatoid arthritis | Surgical Management of Osteoarthritis of the Knee CPG | The effects of total knee arthroplasty (TKA) on the disease activity of rheumatoid arthritis (RA) was investigated in the present study. The disease activity of RA in 58 patients who had undergone simultaneous bilateral TKA (116 knee joints) was examined before, and 1, 6 and 12 months and 3 and 5 years after the operat... |
0 | A gene expression-based predictor for myeloma patients at high risk of developing bone disease on bisphosphonate treatment | MSTS 2018 - Femur Mets and MM | PURPOSE: Myeloma bone disease impairs quality of life and is associated with impaired survival. Even with effective bisphosphonate treatment, a significant proportion of patients still develop skeletal-related events (SRE). Identifying such patients at presentation would allow treatment modification.
EXPERIMENTAL DESIG... |
0 | Potential surrogate outcomes in individuals at high risk for incident knee osteoarthritis | AMP (Acute Meniscal Pathology) | Objective: To study potential surrogate outcomes for osteoarthritis (OA) incidence by evaluating the association of short-term changes in clinical and imaging biomarkers with long-term clinical knee OA incidence. Design: Middle-aged women with overweight/obesity, but free of knee symptoms were recruited through their g... |
0 | An individual patient data meta-analysis on characteristics, treatments and outcomes of the glioblastoma/gliosarcoma patients with central nervous system metastases reported in literature until 2013 | MSTS 2022 - Metastatic Disease of the Humerus | Dissemination of high-grade gliomas (WHO IV) has been investigated poorly so far. We conducted an extensive analysis of the characteristics, treatments and outcomes of the glioblastoma multiforme (GBM)/gliosarcoma (GS) patients with central nervous system (CNS) metastases reported in literature until April 2013. PubMed... |
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