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0 | Isolated patellofemoral arthroplasty | PJI DX Updated Search | Patellofemoral arthroplasty has been described as an appropriate treatment for isolated patellofemoral arthritis. With the aging population and the increasing number of total joint arthroplasties, both patients and surgeons are on the lookout for alternatives to total joint arthroplasty. With appropriate patient select... |
0 | Identification of good candidates for valgus bracing as a treatment for medial knee osteoarthritis | OAK 3 - Non-arthroplasty tx of OAK | Valgus unloader braces are a conservative treatment option for medial compartment knee osteoarthritis that aim to unload the damaged medial compartment through application of an external abduction moment. Patient response to bracing is highly variable, however. While some experience improvements in pain, function, and ... |
0 | Monoclonal antibody: The corner stone of modern biotherapeutics | MSTS 2018 - Femur Mets and MM | Worldwide sales of biologic drugs exceeded 100 billion USD in 2011. About 32% is from therapeutic monoclonal antibody (mAb). With many blockbuster biopharmaceutical patents expiring over the next decade, there is a great opportunity for biosimilar to enter the worldwide especially emerging market. Both European Medicin... |
1 | Aquatic Exercise for the Treatment of Hip and Knee Osteoarthritis | OAK 3 - Non-arthroplasty tx of OAK | <LEAP> highlights the findings and application of Cochrane reviews and other evidence pertinent to the practice of physical therapy. The Cochrane library is a respected source of reliable evidence related to health care. Cochrane systematic reviews explore the evidence for and against the effectiveness and appropriaten... |
0 | Randomized clinical trial of zoledronic acid in multiple myeloma patients undergoing high-dose chemotherapy and stem-cell transplantation | MSTS 2018 - Femur Mets and MM | Background A growing body of evidence is demonstrating that the nitrogen-containing bisphosphonate zoledronic acid (zol) improves clinical outcomes in various cancer settings, including multiple myeloma. Those findings provided the rationale for conducting an open-label randomized controlled phase iii trial to evaluate... |
0 | New body contouring technique in male: the muscular sculpture | Panniculectomy & Abdominoplasty CPG | UNLABELLED: Optimal male body contouring considers the entire body and drapes tight skin over the muscles. Males have pride in the appearance of their muscular development. There should be a deliberate effort to achieve an athletic body contour that reveals superficial musculature and selectively highlights adherences.... |
0 | Fishtail deformity of the distal humerus: a report of 15 cases | The Treatment of Pediatric Supracondylar Humerus Fractures AUC | BACKGROUND: Osteonecrosis of the humeral trochlea is an uncommon but challenging complication of pediatric elbow fractures. The purpose of this investigation was to characterize the clinical and radiographic presentation of fishtail deformity and outline a treatment algorithm. METHODS: Fourteen patients were treated at... |
0 | Imaging of the Painful Hip Arthroplasty | PJI DX Updated Search | The incidence of complications following total hip arthroplasty is low, but due to the frequency of the procedure, they are quite commonly encountered and require appropriate investigation. Complications include aseptic loosening, infection, foreign body granulomatosis (osteolysis), adverse reactions to metal debris, p... |
1 | Effect of unloading brace treatment on pain and function in patients with symptomatic knee osteoarthritis: the ROTOR randomized clinical trial | OAK 3 - Non-arthroplasty tx of OAK | Evidence is still inconclusive for the benefits of bracing in patients with knee osteoarthritis. To assess the effect of REBEL RELIEVER unloading knee brace in conservative treatment of knee osteoarthritis, a randomized controlled trial was conducted in 67 patients with symptomatic medial knee osteoarthritis, who rando... |
0 | Gallium-modified chitosan/poly(acrylic acid) bilayer coatings for improved titanium implant performances | Dental Implant Infection | A gallium-modified chitosan/poly(acrylic acid) bilayer was obtained by electrochemical techniques on titanium to reduce orthopaedic and/or dental implants failure. The bilayer in vitro antibacterial properties and biocompatibility were evaluated against Escherichia coli and Pseudomonas aeruginosa and on MG63 osteoblast... |
0 | Arm contouring after massive weight loss: Liposuction-assisted brachioplasty versus standard technique | Panniculectomy & Abdominoplasty CPG | Massive weight loss (MWL) brachioplasty is frequently requested for the improvement of the appearance and function of arms. Despite its diffusion, this procedure can be associated with significant complications. Liposuction-assisted brachioplasty (LAB) preserves the vascular, nervous, and lymphatic network and reduces ... |
0 | Influence of cryosurgery on treatment outcome of low-grade chondrosarcoma | MSTS 2018 - Femur Mets and MM | Successfully managing low-grade chondrosarcomas with margins considered less than wide would minimize the need for extensive reconstruction. We report our experience using cryotherapy as an adjuvant to treat patients with low-grade intracompartmental chondrosarcomas. Ten consecutive patients had intralesional resection... |
0 | Current and Future Applications of Fluorescence Guidance in Orthopaedic Surgery | AMP (Acute Meniscal Pathology) | Fluorescence-guided surgery (FGS) is an evolving field that seeks to identify important anatomic structures or physiologic phenomena with helpful relevance to the execution of surgical procedures. Fluorescence labeling occurs generally via the administration of fluorescent reporters that may be molecularly targeted, en... |
0 | Fracture risk in people with celiac disease: a population-based cohort study | Management of Hip Fractures in the Elderly | BACKGROUND & AIMS: People with celiac disease are at risk of developing osteoporosis, but the extent of any increased fracture risk is unclear. We performed a population-based cohort study by using the General Practice Research Database to quantify the fracture risk in people with celiac disease compared with the gener... |
0 | Muscle deficits persist after unilateral knee replacement and have implications for rehabilitation | PJI DX Updated Search | Background. Knee joint arthritis causes pain, decreased range of motion, and mobility limitation. Knee replacement reduces pain effectively. However, people with knee replacement have decreases in muscle strength ("force-generating capacity") of the involved leg and difficulties with walking and other physical activiti... |
0 | ECM production of primary human and bovine chondrocytes in hybrid PEG hydrogels containing type I collagen and hyaluronic acid | OAK 3 - Non-arthroplasty tx of OAK | The development of advanced materials that facilitate hyaline cartilage formation and regeneration in aging populations is imperative. Critical to the success of this endeavor is the optimization of ECM production from clinically relevant cells. However, much of the current literature focuses on the investigation of pr... |
0 | Risk assessment of new fracture following fragility hip fracture | HipFx Supplemental Cost Analysis | Background: Osteoporosis, a disease with serious socio-economical implication, characterized by bone mass reduction and modifications of internal bone structure, leads to increased bone fragility and to an increased fracture risk. Hip fracture is the major complication of osteoporosis and this appears as a result of a ... |
0 | Arthroscopic Management of Elbow Osteoarthritis | Pediatric Supracondylar Humerus Fracture 2020 Review | The incidence of osteoarthritis in the general population is low, but it can be seen in manual laborers, throwing athletes, and people dependent on crutches and wheelchairs. Patients often complain of pain at the terminal extents of motion, and imaging shows osteophyte formation at the tips of the coronoid and olecrano... |
1 | Antibiotic considerations in medically compromised patients | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | This article discusses bacteremias and dental procedures, medical history taking, and risk assessment considerations for specific medical problems. Recommendations for patient management are reviewed also |
0 | Evaluation of measures to decrease intra-operative bacterial contamination in orthopaedic implant surgery | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | The aim of this study was to evaluate whether behavioural and systemic measures will decrease intra-operative contamination during total hip or knee replacements. The influence of these measures on subsequent prolonged wound discharge, superficial surgical site infection and deep periprosthetic infection was also inves... |
0 | The Effect of AposTherapy on Knee Pain | OAK 3 - Non-arthroplasty tx of OAK | AposTherapy is a homeâ?based exercise program utilizing footwear that causes exercise with normal daily activity that may significantly improve function in patients with knee pain in general, and specifically knee osteoarthritis (OA). Capitalizing on the reported excellent adherence and clinical benefit of Apos Therap... |
0 | Three-dimensional bone scintigraphy using volume-rendering technique and SPECT | MSTS 2018 - Femur Mets and MM | Three-dimensional bone scintigraphic images were made and their usefulness and limitations discussed. Methods: After usual bone scan procedures, single-photon emission computed tomography (SPECT) data were taken and reconstructed into three-dimensional images. Volume rendering methods were used. Results: Three cases of... |
0 | Posttraumatic stress disorder in the National Comorbidity Survey | DoD PRF (Psychosocial RF) | BACKGROUND: Data were obtained on the general population epidemiology of DSM-III-R posttraumatic stress disorder (PTSD), including information on estimated life-time prevalence, the kinds of traumas most often associated with PTSD, sociodemographic correlates, the comorbidity of PTSD with other lifetime psychiatric dis... |
0 | It is the time to think about a treat-to-target strategy for knee osteoarthritis | OAK 3 - Non-arthroplasty tx of OAK | Osteoarthritis (OA) is a rheumatic disease that affects the well-being of the patient, compromises physical and mental function, and affects other quality of life aspects. In the literature, several evidence-based guidelines and recommendations for the management of knee osteoarthritis (KOA) are available. These recomm... |
0 | A review of chronic exertional compartment syndrome in the lower leg | DOD - Acute Comp Syndrome CPG | Chronic exertional compartment syndrome (CECS) in the lower leg has been described as early as 1956. This review describes the five relevant anatomical compartments and the important clinical features on presentation used in diagnosis. Compartment pressure testing using various types of catheter is useful as a confirma... |
0 | C-reactive protein in femoral head necrosis | Management of Hip Fractures in the Elderly | Serum concentrations of C-reactive protein (CRP), alpha 1-antitrypsin, orosomucoid, and haptoglobin were determined in 28 patients with a medial fracture of the femoral neck. The serum concentrations were compared with the result of hip scintigraphy with technetium-99m pyrophosphate, a method which can detect femoral h... |
0 | Review of discoid meniscus | AMP (Acute Meniscal Pathology) | Discoid lateral meniscus is an intra-articular knee disorder that typically presents in children and adolescents. The natural history depends on the type of anomaly and the nature and presence of symptoms. Management of this disorder should be directed toward resolution of the symptoms while preserving meniscal tissue ... |
0 | A special guide for insertion of multiple pins for fracture of the hip: experience with 200 cases | Management of Hip Fractures in the Elderly | Two hundred cases of intracapsular femoral neck fractures have been treated with a multiple parallel pin technique similar to that originated by Austin Moore. The technique employs a personally designed guide which facilitates insertion of multiple parallel pins. The fixation obtained satisfactorily resists shear stres... |
0 | Mapping the cellular and molecular heterogeneity of normal and malignant breast tissues and cultured cell lines | Reduction Mammoplasty for Female Breast Hypertrophy | INTRODUCTION: Normal and neoplastic breast tissues are comprised of heterogeneous populations of epithelial cells involving various degrees of maturation and differentiation. While cultured cell lines have been derived from both normal and malignant tissues, it remains unclear whether they retain a similar cellular het... |
0 | Age-associated decline in human femoral neck cortical and trabecular content of insulin-like growth factor I: potential implications for age-related (type II) osteoporotic fracture occurrence | Management of Hip Fractures in the Elderly | Recent evidence suggests that regulatory peptides such as insulin-like growth factor-I (IGF-I) are released locally from bone during resorption, and may then act in a sequential manner to regulate the cellular events required for the coupling of bone formation to resorption. Among other factors, a decrease in bone-asso... |
0 | HACEK group endocarditis at the Riyadh Armed Forces Hospital | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | INTRODUCTION: Fastidious Gram-negative organisms classified as the HACEK group (Haemophilus spp., Actinobacillus actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens and Kingella spp.) are rare causes of infective endocarditis. CASE REPORT: In this series, we report six cases of endocarditis in Saudi pat... |
0 | Periocular ulcerative dermatitis associated with gentamicin ointment prophylaxis in newborns | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | A recent shortage of erythromycin ointment has resulted in the use of alternative agents for newborn ocular infection prophylaxis in the United States. We report a series of 26 newborns in whom a characteristic periocular ulcerative dermatitis developed after gentamicin ointment administration at 2 Philadelphia hospita... |
0 | Supracondylar fractures of the humerus | The Treatment of Pediatric Supracondylar Humerus Fractures AUC | Supracondylar fractures of the humerus are one of the most common fractures of childhood. With the recognised complications of cubitus varus, injury to any of the three major nerves around the elbow, absent radial pulse after fracture reduction, stiffness and the fortunately rare incidence of Volkmann's ischaemic contr... |
0 | Factors Affecting Short-Term Rehabilitation Outcomes of Disabled Elderly Patients With Proximal Hip Fracture | Hip Fx in the Elderly 2019 | Hershkovitz A, Kalandariov Z, Hermush V, Weiss R, Brill S. Factors affecting short-term rehabilitation outcomes of disabled elderly patients with proximal hip fracture. Objective: To identify factors associated with postacute rehabilitation outcome of disabled elderly patients with proximal hip fracture. Setting: Geria... |
0 | Cement removal and bone bed preparation of the femoral medullary canal assisted by flexible endoscope in total hip revision arthroplasty | Dental Implant Infection | PURPOSE: The flexible endoscope was applied to cemented femoral medullary canal to obtain better visual field and assist surgical procedures in total hip revision arthroplasty., METHODS: Fifteen cases of failed cemented total hip joints were analyzed. Efficacy of cement removal was assessed, combined with degree of imp... |
0 | Downregulation of lncRNA SNHG14 attenuates osteoarthritis by inhibiting FSTL-1 mediated NLRP3 and TLR4/NF-kappaB pathway through miR-124-3p | AMP (Acute Meniscal Pathology) | Osteoarthritis (OA) is the joint pain and dysfunction syndrome caused by severe joint degeneration. The overproduced inflammatory mediators contribute greatly to OA development. It is reported that long non-coding RNA (lncRNA) takes part in many inflammatory diseases. Here, we mainly explored the function of lncRNA SNH... |
0 | A novel adaptation of a parent-child observational assessment tool for appraisals and coping in children exposed to acute trauma | DoD PRF (Psychosocial RF) | BACKGROUND: Millions of children worldwide are exposed to acute potentially traumatic events (PTEs) annually. Many children and their families experience significant emotional distress and/or functional impairment following PTEs. While current research has begun to highlight a role for early appraisals and coping in pr... |
0 | Lower limb ischemia caused by resuscitative balloon occlusion of aorta | DoD LSA (Limb Salvage vs Amputation) | BACKGROUND: Resuscitative endovascular balloon occlusion of the aorta (REBOA) is an emergency procedure to manage severe hemorrhagic shock from torso injury but can cause severe ischemia of the lower extremities. However, lower extremity ischemia occurring as a complication of REBOA has been rarely reported. We describ... |
0 | The effect of training programs on traditional approaches that mothers use in emergencies | DoD PRF (Psychosocial RF) | INTRODUCTION: The approach of the residents of central Kars, Turkey, to emergencies in our conservative district is shaped by the effect of the culture. In emergency actions, many traditional approaches are preferred, using herbs and other available materials. Some of these approaches might be directly hazardous and so... |
1 | Heparin, low molecular weight heparin and physical methods for preventing deep vein thrombosis and pulmonary embolism following surgery for hip fractures | Management of Hip Fractures in the Elderly | BACKGROUND: Hip fracture patients have a high risk of thrombo-embolic complications following surgical management. OBJECTIVES: To examine the effects of heparin (unfractionated (U), and low molecular weight (LMW) heparins), and physical methods (compression stockings, calf or foot pumps) for prevention of deep venous t... |
0 | Evaluation of the superior gluteal nerve during proximal femoral nailing | Hip Fx in the Elderly 2019 | Aim: The superior gluteal nerve may be compromised during hip surgery. We retrospectively evaluated the patients who underwent proximal femoral nail-ing for unstable trochanteric fractures in order to investigate the presence of superior gluteal nerve injury and its clinical findings. Material and Method: Twenty five p... |
1 | Functional Assessment of Arthroscopic Repair for Recurrent Anterior Shoulder Instability | Glenohumeral Joint OA | OBJECTIVE: To clinically and radiologically evaluate patients who underwent arthroscopic surgical treatment for anterior shoulder instability by means of the Bankart technique, using metal anchors.
METHODS: This was a retrospective study on 49 patients who underwent arthroscopic repair of anterior shoulder instability ... |
1 | Clinical features and walking ability in the early postoperative period after treatment of trochanteric hip fractures. Results with special reference to fracture type and surgical treatment | Management of Hip Fractures in the Elderly | The purpose of this study was to analyze the functional outcome during the early postoperative period (six weeks) in patients with trochanteric fractures. A consecutive series of 149 patients were randomized to treatment with either the DHS or Ender operative technique. 120 patients were available at review six weeks a... |
0 | Application of bone morphogenetic protein 7 in the orthopedics | SR for PM on OA of All Extremities | Background: Bone morphogenetic protein (BMP) family have the unique ectopic osteoinduction activity. They are related with development of embryonic tissue, functions maintenance and organizational rebuilding. BMPs are important to osteoinduction activity. BMP7, one of BMPs, mainly in bone and kidney, is essential for d... |
0 | Stand up and be counted: measuring time spent upright after hip fracture and comparison with community dwelling older people | Management of Hip Fractures in the Elderly | Objectives: Following hip fracture, the amount of time an individual spends on their feet ('uptime') may be an important marker of recovery. Using an automated device that measured uptime (Uptimer), we aimed to: (1) compare hip fracture patients' uptime with age- and gender-matched community dwelling older people; (2) ... |
0 | Preservation of oral health-related quality of life and salivary flow rates after inverse-planned intensity- modulated radiotherapy (IMRT) for head-and-neck cancer | Dental Implant Infection | PURPOSE: To assess whether comprehensive bilateral neck intensity-modulated radiotherapy (IMRT) for head-and-neck cancer results in preserving of oral health-related quality of life and sparing of salivary flow in the first year after therapy., METHODS AND MATERIALS: Twenty-three patients with head-and-neck cancer (pri... |
0 | Reduction of verbal pain scores after anterior cruciate ligament reconstruction with 2-day continuous femoral nerve block: a randomized clinical trial | Surgical Management of Osteoarthritis of the Knee CPG | BACKGROUND: Single-injection femoral nerve block analgesia and spinal anesthesia have been associated with fewer postoperative nursing interventions and successful same-day discharge after anterior cruciate ligament reconstruction. In the current study, the authors prospectively determined the effect of continuous femo... |
0 | Treatment of Unstable Intertrochanteric Fractureswith Proximal Femoral Nail Antirotation II: Our Experience in Indian Patients | Hip Fx in the Elderly 2019 | INTRODUCTION: Unstable intertrochanteric fractures are difficult to manage and the choice of implant is critical for fracture fixation. The purpose of this study was to evaluate the functional and radiological outcome of proximal femoral nail antirotationII (PFNA II) in the treatment of unstable intertrochanteric fract... |
0 | Modelling and estimation of healthrelated quality of life after hip fracture: A re-analysis of data from a prospective cohort study | Hip Fx in the Elderly 2019 | Objectives: This study investigates the reporting of health-related quality of life (HRQoL) in patients following hip fracture. We compare the relative merits and make recommendations for the use for two methods of measuring HRQoL; (i) including patients who died during follow-up and (ii) including survivors only. Meth... |
0 | Long-term results of total knee arthroplasty following high tibial osteotomy according to Wagner | Surgical Management of Osteoarthritis of the Knee CPG | PURPOSE: There is relatively little information available about the long-term results of total knee arthroplasty (TKA) following high tibial osteotomy. The aim of our study was to share our experiences and long-term results of TKA after a previous closing wedge high tibial osteotomy according to Wagner. METHODS: In a r... |
0 | Relationship of femoral bone density with gender of study to be acquainted with the prevalence of regional osteoporosis in patients | Hip Fx in the Elderly 2019 | Worldwide, the quantity of hip fractures, the maximum essential osteoporotic hardship in the ageing, keeps to upsurge consistent with the getting old of the population. Bone mineral density (BMD) is the quantity of the minerals, in the main calcium and phosphorous, controlled insure extent of bone to identify osteoporo... |
0 | Use of diffusion tensor imaging for nonsurgical treatments of carpal tunnel syndrome | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | INTRODUCTION: This study evaluated the applicability of diffusion tensor imaging (DTI) of therapeutic ultrasound (US) and wrist splints in addition to clinical and electrophysiological assessments of patients with carpal tunnel syndrome (CTS). METHODS: This prospective study analyzed 41 patients (30 women, 11 men; 56 w... |
0 | Lower Extremity Assessment Project (LEAP)--the best available evidence on limb-threatening lower extremity trauma | DoD LSA (Limb Salvage vs Amputation) | Lower Extremity Assessment Project (LEAP) study set out to answer many of the questions surrounding the decision of whether to amputate or salvage limbs in the setting of severe lower extremity trauma. A National Institutes of Health-funded, multicenter, prospective observational study, the LEAP study represented a mil... |
0 | Targeting pioglitazone hydrochloride therapy after stroke or transient ischemic attack according to pretreatment risk for stroke or myocardial infarction | DoD PRF (Psychosocial RF) | Importance: There is growing recognition that patients may respond differently to therapy and that the average treatment effect from a clinical trial may not apply equally to all candidates for a therapy. Objective: To determine whether, among patients with an ischemic stroke or transient ischemic attack and insulin re... |
0 | The association of greater dispositional optimism with less endogenous pain facilitation is indirectly transmitted through lower levels of pain catastrophizing | OAK 3 - Non-arthroplasty tx of OAK | UNLABELLED: Dispositional optimism has been shown to beneficially influence various experimental and clinical pain experiences. One possibility that may account for decreased pain sensitivity among individuals who report greater dispositional optimism is less use of maladaptive coping strategies such as pain catastroph... |
0 | Risk factors for symptomatic hypocalcaemia complicating treatment with zoledronic acid | MSTS 2018 - Femur Mets and MM | BACKGROUND: The bisphosphonate zoledronic acid is commonly prescribed to prevent skeletal complications in patients with multiple myeloma or metastatic cancer. Although symptomatic hypocalcaemia is a potential risk of treatment, it has been thought to be uncommon.
AIMS: After seeing several episodes of symptomatic hypo... |
0 | Meniscus Repair Does Not Result in an Inferior Short-term Outcome Compared With Meniscus Resection: An Analysis of 5,378 Patients With Primary Anterior Cruciate Ligament Reconstruction | AMP (Acute Meniscal Pathology) | PURPOSE: To compare the preoperative and 1- and 2-year postoperative Knee Injury and Osteoarthritis Outcome Score (KOOS) subscale scores between isolated anterior cruciate ligament reconstruction (ACLR) and ACLR with additional medial meniscus (MM) and/or lateral meniscus (LM) resection or repair.
METHODS: A total of 5... |
0 | Amputation rate and risk factors in type 2 patients with diabetic foot syndrome under real-life conditions in Germany | DoD PRF (Psychosocial RF) | Aims: To determine the risk of amputation and the influencing factors for amputation for patients with type 2 diabetes with diabetic foot syndrome. Methods: Longitudinal data from general practices in Germany (Disease Analyzer database, IMS Health) were analyzed. 3892 type 2 diabetes patients (mean age: 66.0 (SD: 10.9 ... |
1 | Does Use of Oral Anticoagulants at the Time of Admission Affect Outcomes Following Hip Fracture | Hip Fx in the Elderly 2019 | Purpose: The purpose of this study was to compare hospital quality outcomes in patients over the age of 60 undergoing fixation of hip fracture based on their anticoagulation status.
Materials and Methods: Patients aged 60 and older with isolated hip fracture injuries treated operatively at 1 academic medical center bet... |
0 | Plastic adhesive drapes and wound infection after hip fracture surgery | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | One hundred and twenty patients with acute hip fractures treated operatively were randomized into two groups. In the 'drape' group (n = 65) the operation site was covered with plastic adhesive drape after preparation. In the 'no drape' group (n = 55) the operation site was left uncovered. The two groups were otherwise ... |
0 | Heritabilities of osteochondral lesions and genetic correlations with production and exterior traits in station-tested pigs | Osteochondritis Dissecans 2020 Review | Osteochondrosis might reduce the performance of slaughter pigs, longevity of sows and animal welfare. The aim of the present work was to describe the prevalence in Swiss breeds and to analyse the genetic background of osteochondral lesions. Between January 2002 and December 2005, about 9500 station-tested pigs were exa... |
0 | CXCR4 antagonist 4F-benzoyl-TN14003 inhibits leukemia and multiple myeloma tumor growth | MSTS 2018 - Femur Mets and MM | OBJECTIVE: The chemokine receptor CXCR4 and its ligand CXCL12 are involved in the progression and dissemination of a diverse number of solid and hematological malignancies. Binding CXCL12 to CXCR4 activates a variety of intracellular signal transduction pathways that regulate cell chemotaxis, adhesion, survival, prolif... |
1 | Injury patterns of medial meniscus posterior root tears | AMP (Acute Meniscal Pathology) | INTRODUCTION: Medial meniscus posterior root tear (MMPRT) can occur in middle-aged patients who have a posteromedial painful popping during light activities. MMPRTs are more common in patients with increased age, female gender, sedentary lifestyle, obesity, and varus knee alignment. However, injury mechanisms of minor ... |
0 | Complications of methylene blue dye in breast surgery: case reports and review of the literature | Reduction Mammoplasty for Female Breast Hypertrophy | INTRODUCTION: Methylene blue dye has been used worldwide successfully with few complications in breast surgery. We present two different complications involving methylene blue: 1) skin and parenchymal necrosis when dye was injected in a subdermal fashion and 2) Mycoplasma infection caused by contaminated methylene blue... |
0 | Gonadotrophin-releasing hormone analogues for endometriosis: bone mineral density | Management of Hip Fractures in the Elderly | BACKGROUND: Gonadotrophin-releasing hormone analogues (GnRHas) are generally well tolerated, and are effective in relieving the symptoms of endometriosis (Prentice 2003). Unfortunately the low oestrogen state that they induce is associated with adverse effects including an acceleration in bone mineral density (BMD) los... |
0 | Negative pressure wound therapy and external fixation device: A simple way to seal the dressing | Pediatric Supracondylar Humerus Fracture 2020 Review | Summary: Negative pressure therapy is widely applied to treat lower limb trauma. However, sealing a negative pressure dressing in the presence of an external fixation device may be difficult and time consuming. Therefore, screws, pins, wires, etc, may preclude the vacuum, preventing the plastic drape to perfectly adher... |
0 | Metabolic rewiring controlled by c-Fos governs cartilage integrity in osteoarthritis | AMP (Acute Meniscal Pathology) | OBJECTIVES: The activator protein-1 (AP-1) transcription factor component c-Fos regulates chondrocyte proliferation and differentiation, but its involvement in osteoarthritis (OA) has not been functionally assessed.
METHODS: c-Fos expression was evaluated by immunohistochemistry on articular cartilage sections from pat... |
0 | Vascular safety during arthroscopic all-inside meniscus suture | AMP (Acute Meniscal Pathology) | PURPOSE: The purpose of the study is to assess the orientation and distance of the popliteal artery (PA) from both the anteromedial and anterolateral portals.
METHODS: The records of 97 patients (100 knees) who underwent knee arthroscopy were reviewed. The shortest distance from the posterior tibial cortex to the PA on... |
0 | Comparison of mortality in ESRD patients on convective and diffusive extracorporeal treatments | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Comparison of mortality in ESRD patients on convective and diffusive extracorporeal treatments. Background. The aim of this study was to evaluate the effect of convective [hemodiafiltration (HDF) or hemofiltration (HF)] versus diffusive treatments [hemodialysis (HD)] on end-stage renal disease (ESRD) patient mortality ... |
0 | Comparative whole-body 201Tl and bone scintigraphies for the detection of bone marrow involvement in multiple myeloma | MSTS 2018 - Femur Mets and MM | The objectives of this study were to investigate the role of wholeÎ?Ã?Ã?body 201TlÎ?Ã?Ã?chloride scintigraphy in comparison with bone scintigraphy in the detection of bone marrow involvement in patients with multiple myeloma and to assess the followÎ?Ã?Ã?up evaluation using 201TlÎ?Ã?Ã?chloride. TwentyÎ?Ã?Ã?one patients... |
0 | Polytrauma and High-energy Injury Mechanisms are Associated with Worse Patient-reported Outcomes after Distal Radius Fractures | Hip Fx in the Elderly 2019 | BackgroundPatient-reported outcomes (PROs) are increasingly relevant when evaluating the treatment of orthopaedic injuries. Little is known about how PROs may vary in the setting of polytrauma or secondary to high-energy injury mechanisms, even for common injuries such as distal radius fractures.Questions/purposes(1) A... |
0 | Serum lidocaine and bupivacaine levels in local technique knee arthroscopy | Surgical Management of Osteoarthritis of the Knee CPG | We investigated serum levels of lidocaine and bupivacaine following their intraarticular and subcutaneous injection for anesthetic effect in local technique knee arthroscopy. Fifteen patients scheduled for knee arthroscopy, but who were otherwise healthy, were studied. Following preparation of the knee, 25 cc of 1% lid... |
0 | Reconstruction of elbow skin and soft tissue defects using perforator-pedicled propeller flaps | Pediatric Supracondylar Humerus Fracture 2020 Review | BACKGROUND: The elbow is a challenging region to reconstruct functionally. Several closure methods for elbow wounds have been reported, including flap surgery. Here, we present the results obtained using a propeller flap pedicled by a posterior ulnar recurrence artery perforator (PURAP) or a radial collateral artery pe... |
1 | Short-term outcomes of local infiltration anaesthetic in total knee arthroplasty: a randomized controlled double-blinded controlled trial | AAHKS (8) Anesthetic Infiltration | BACKGROUND: The primary objective of the study was to determine if local infiltration anaesthetic (LIA) reduced total length of hospital stay in total knee arthroplasty (TKA) patients. The study also examined whether LIA improves early pain management, patient satisfaction and range of motion in TKA patients.
METHODS: ... |
0 | Women's sexual function and dysfunction: Current uncertainties, future directions | DoD PRF (Psychosocial RF) | There is increasing evidence that women at the outset of sexual activity do not need to have sexual desire, as in 'drive', and that many do not distinguish desire from arousal. Multiple modes of investigation confirm poor correlation between women's subjective arousal and measured genital congestion. Suggested revision... |
0 | Patient-reported outcomes following primary total hip arthroplasty in Crowe type III or IV developmental dysplasia are comparable to those in Crowe type I: A case-control study of 96 hips with intermediate-term follow-up | Hip Fx in the Elderly 2019 | Background: A few previous studies have investigated patient satisfaction after total hip arthroplasty (THA) according to the degree of pelvic deformity. This study compared patient-reported outcomes after primary THA for Crowe types III, IV and I dysplasia. Methods: This retrospective, single-center, single-surgeon ca... |
0 | Progenitor cells from different zones of human cartilage and their correlation with histopathological osteoarthritis progression | OAK 3 - Non-arthroplasty tx of OAK | Cell-based therapies development for the treatment of osteoarthritis (OA) requires an understanding of the disease progression and attributes of the cells resident in cartilage. This study focused on quantitative assessment of the concentration and biological potential of stem and progenitor cells resident in different... |
0 | Comparison of bone mineral density in both hips | Management of Hip Fractures in the Elderly | Dual-photon absorptiometry (DPA) was performed on both hips of 40 patients to determine if the calculated bone-mineral density (BMD) of one hip could be used to predict the BMD of the opposite hip. For the Ward triangle, femoral neck, and greater trochanter the correlation coefficients between the BMD of the two hips w... |
0 | Effect of refrigeration in the viability and apoptosis of decanted adipocytes after liposuction | Panniculectomy & Abdominoplasty CPG | OBJETIVO: Evaluar el efecto de la refrigeración en la apoptosis y la viabilidad del lipoaspirado en las primeras 2 horas después de la toma. MÉTODO: Se incluyeron 20 pacientes que fueron sometidas a una liposucción del abdomen por razones estéticas. Se obtuvieron 5 ml de grasa y se procesaron para su estudio. La viabil... |
1 | Developing and testing a measure of COVID-19 organizational support of healthcare workers - results from Peru, Ecuador, and Bolivia | Coronavirus Disease 2019 (COVID-19) | During the COVID-19 pandemic, healthcare workers are facing high workloads with resource constraints and risk of virus exposure, and healthcare organizations need to support their healthcare workers to reduce their anxiety. Based on a recent 8-point framework of COVID-19 specific organization support, we devised a meas... |
1 | Massive cutback in orthopaedic healthcare services due to the COVID-19 pandemic | Coronavirus Disease 2019 (COVID-19) | PURPOSE: Due to the lack of evidence, it was the aim of the study to investigate current possible cutbacks in orthopaedic healthcare due to the coronavirus disease 2019 pandemic (COVID-19). METHODS: An online survey was performed of orthopaedic surgeons in the German-speaking Arthroscopy Society (Gesellschaft für Arth... |
0 | Outcome of 28 open pilon fractures with injury severity-based fixation | DoD LSA (Limb Salvage vs Amputation) | INTRODUCTION: Open pilon fracture management and treatment poses a significant challenge to orthopedic surgeons. The purpose of this study was to determine patient outcomes for open pilon fractures based on wound complication and infection rates, as well as subjective outcome instruments. MATERIALS AND METHODS: This wa... |
0 | Depressed levels of circulating menaquinones in patients with osteoporotic fractures of the spine and femoral neck | Management of Hip Fractures in the Elderly | Vitamin K1 functions in the conversion of glutamate residues, present in certain bone peptides, into the putatively active gamma-carboxyglutamate form. We have shown previously that the circulating levels of vitamin K1 are depressed in osteoporotic patients. However, it is known that menaquinones (vitamin K2:MK) may be... |
1 | Crossed abdominal wall plication in abdominoplasty | Panniculectomy & Abdominoplasty CPG | Objectives Plication of the anterior abdominal wall musculature and the anterior rectus sheath is a common procedure during abdominoplasty. The purpose of this study was to compare a newly modified technique for oblique plication of the anterior rectus sheath with classic vertical rectus plication, on the assumption th... |
0 | Minimum 10-year follow-up results of ALPINA cementless hydroxyapatite- coated anatomic unicompartmental knee arthroplasty | OAK 3 - Non-arthroplasty tx of OAK | One hundred and one unicompartmental knee arthroplasties (UKA) were done between 1996 and 2000 with ALPINA® UNI, a cementless hydroxyapatite-coated anatomic prosthesis. Sixty-five knees were available for the long-term follow-up at a mean of 11 years. The mean IKS improved from 119.3 ± 16.8 points preoperatively to 1... |
1 | A meta-analysis of dexamethasone for pain management in patients with total knee arthroplasty | AAHKS (2) Corticosteroids | BACKGROUND: Pain management after a total-knee arthroplasty (TKA) has become an important issue in the field of medicine. This study conducted a meta-analysis from randomized controlled trials (RCTs) to assess the efficacy and safety of dexamethasone for pain management after TKA.
METHODS: PubMed, Medline, Embase, Scie... |
0 | Autologous bone marrow grafting combined with demineralized bone matrix improves consolidation of docking site after distraction osteogenesis | DoD SSI (Surgical Site Infections) | BACKGROUND: Distraction osteogenesis is used for the reconstruction of extensive osseous defects. Delay in docking site consolidation results in significant prolongation of this surgical procedure. The primary aim of the present study was to retrospectively compare three different treatment options, all aimed at improv... |
0 | Evaluation of a concentric biopsychosocial model of well-being in persons with spinal cord injuries | DoD PRF (Psychosocial RF) | OBJECTIVE: The objective of this study was to evaluate a concentric biopsychosocial model of well-being in individuals with spinal cord injuries (SCI).
METHOD: Adults (N = 235) with SCI participated in this study. A cross-sectional design with hierarchical regression and Andrew Hayes' (2013) PROCESS mediation analysis ... |
1 | Sonication of antibiotic-loaded cement spacers in a two-stage revision protocol for infected joint arthroplasty | PJI DX Updated Search | BACKGROUND: Culturing of the sonication fluid of removed implants has proven to be more sensitive than conventional periprosthetic tissue culture for the microbiological diagnosis of prosthetic joint infection. Since bacteria surviving on antibiotic-loaded cement spacers used in a two-stage exchange protocol for infect... |
0 | Head and neck squamous cell carcinoma in 13 patients with fanconi anemia after hematopoietic stem cell transplantation | Reconstruction After Skin Cancer | BACKGROUND. Fanconi anemia (FA) is a chromosomal instability disorder with a very high risk of developing head and neck squamous cell carcinoma (HNSCC), most notably after hematopoietic stem cell transplantation (HSCT). METHODS. In the current study, the authors reported 13 cases of HNSCC in FA patients who underwent H... |
0 | Decompression of the orbit and the optic nerve in different diseases | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | During the past six years, visual loss in 60 patients was caused by infectious processes and mucoceles of the ethmoid region, benign paranasal tumours, endocrine ophthalmopathies, head trauma etc. Comparison of preoperative and postoperative visual function in 48 cases treated by decompression of the orbit and in 12 ca... |
0 | Regenerative treatment of male stress urinary incontinence by periurethral injection of autologous adipose-derived regenerative cells: 1-year outcomes in 11 patients | Panniculectomy & Abdominoplasty CPG | Objectives: To assess the efficacy and safety of a novel cell therapy for male stress urinary incontinence consisting of periurethral injection of autologous adipose-derived regenerative cells, and to determine the 1-year outcomes. Methods: A total of 11 male patients with persistent stress urinary incontinence after p... |
0 | An ultrasonographic assessment of nerve stimulation-guided median nerve block at the elbow: A local anesthetic spread, nerve size, and clinical efficacy study | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Background: Nerve stimulation is an effective technique for peripheral nerve blockade. However, the local anesthetic (LA) distribution pattern obtained with this blind approach is unknown and may explain its clinical effects. Methods: One hundred patients received a median nerve block at the elbow using a nerve stimula... |
0 | Joint motion of bipolar femoral prostheses | Management of Hip Fractures in the Elderly | From 1982 to 1991, 251 bipolar hip arthroplasties were performed on 213 patients. Among them, 117 bipolar femoral prostheses were randomly selected to examine the behavior of abduction motion under weight-bearing loads. Roentgenographic motion study was performed at an average of 46.5 months after surgery (range, 2-110... |
0 | The effect of intraarticular levobupivacaine and bupivacaine injection on the postoperative pain management in total knee artroplastic surgery | AAHKS (4) Acetaminophen | OBJECTIVE: Total knee arthroplasty (TKA) is associated with considerable postoperative pain. We compared the effects of intraoperative intraarticular levobupivacaine and bupivacaine on postoperative analgesia and analgesic consumption after total knee arthroplasty.
METHODS: Sixty ASA (American Society of Anesthesiologi... |
1 | Does Adductor Canal Block Have a Synergistic Effect with Local Infiltration Analgesia for Enhancing Ambulation and Improving Analgesia after Total Knee Arthroplasty? | AAHKS (8) Anesthetic Infiltration | Purpose: We compared a single-injection adductor canal block (ACB) with or without local infiltration analgesia (LIA) for accelerating functional recovery and reducing postoperative pain after total knee arthroplasty (TKA).
Materials and Methods: Sixty-two patients undergoing TKA with simple spinal analgesia and ACB we... |
0 | (i) Indications for internal fixation of fractures in children | The Treatment of Pediatric Supracondylar Humerus Fractures AUC | The nature of most fractures in children makes them suitable for closed management. However, functional outcomes are not uniformly good and there is evidence that poorer outcomes may be under-reported in children. The role for internal fixation is becoming better-defined. Most Salter Harris type I and II fractures are ... |
0 | Macro- to microscale strain transfer in fibrous tissues is heterogeneous and tissue-specific | AMP (Acute Meniscal Pathology) | Mechanical deformation applied at the joint or tissue level is transmitted through the macroscale extracellular matrix to the microscale local matrix, where it is transduced to cells within these tissues and modulates tissue growth, maintenance, and repair. The objective of this study was to investigate how applied tis... |
0 | High expression of CXCR7 combined with Alpha fetoprotein in hepatocellular carcinoma correlates with extra-hepatic metastasis to lung after hepatectomy | MSTS 2018 - Femur Mets and MM | The lung is the most frequent metastatic site of hepatocellular carcinoma (HCC), negatively impacting on survival rates. In this study, we evaluated the prognostic role of the chemokine receptor CXCR7 in lung metastasis of HCC after hepatectomy, using immunohistochemical detection on tissue microarrays of HCCs, with an... |
0 | Function, post-traumatic sequelae and current concepts of management of knee meniscus injuries: a review article | AMP (Acute Meniscal Pathology) | Long thought to be expendable or insignificant for function, the menisci may well be very important structures in the knee joint. Menisci are of critical importance from the standpoint of stability, shock absorption, load transmission, and lubrication, and also play a role in preventing synovial impingement, and in def... |
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