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0 | Family experience with osteogenesis imperfecta type 1: the most distressing situations | DoD PRF (Psychosocial RF) | BACKGROUND: Osteogenesis imperfecta (OI) is a rare genetic disorder characterized by decreased bone mass and increased bone fragility. Despite increasing research on the biomedical aspects of the disease, only a few studies focus on the psychosocial implications of living with OI. This study aimed to explore the situat... |
0 | D-dimer improves risk prediction of venous thromboembolism in patients with multiple myeloma | MSTS 2022 - Metastatic Disease of the Humerus | Introduction: Venous thromboembolism (VTE) is a common cause of morbidity and mortality among patients with multiple myeloma (MM). Thromboprophylaxis is a safe and effective way to decrease VTE in other high-risk populations. Recently, a clinical prediction model was developed to identify patients with newly diagnosed ... |
0 | Structure-modifying effects of chondroitin sulfate in knee osteoarthritis: an updated meta-analysis of randomized placebo-controlled trials of 2-year duration | SR for PM on OA of All Extremities | OBJECTIVE: To update a published meta-analysis of double-blind placebo-controlled randomized clinical trials (RCTs) to assess the efficacy of chondroitin sulfate as a structure-modifying drug for knee osteoarthritis (OA). DESIGN: A published meta-analysis of randomized controlled trials was updated to include data from... |
0 | A comparison of various ultrasound technologies | Panniculectomy & Abdominoplasty CPG | Ultrasound-assisted lipoplasty represents a new and exciting adjunct to traditional suction-assisted lipoplasty techniques. With the development of this new field, a variety of special equipment needs have arisen. Most important among these needs are the ultrasonic generator, handpiece, and probe. This article critical... |
0 | Wide versus narrow excision margins for high-risk, primary cutaneous melanomas: long-term follow-up of survival in a randomised trial | Reconstruction After Skin Cancer | Background: The necessary margin of excision for cutaneous melanomas greater than 2 mm in thickness is controversial. At a median follow-up of 5 years, findings from our previously published randomised trial of narrow (1 cm) versus wide (3 cm) excision margins in patients with thick cutaneous melanomas showed that narr... |
0 | Structural effects of sprifermin in knee osteoarthritis: a post-hoc analysis on cartilage and non-cartilaginous tissue alterations in a randomized controlled trial | OAK 3 - Non-arthroplasty tx of OAK | BACKGROUND: A recent publication on efficacy of Sprifermin for knee osteoarthritis (OA) using quantitatively MRI-defined central medial tibio-femoral compartment cartilage thickness as the structural primary endpoint reported no statistically significant dose response. However, Sprifermin was associated with statistica... |
1 | Predictive value of nerve conduction measurements at the carpal tunnel | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | We compared the predictive values of three measurements of sensory conduction of the median nerve at the carpal tunnel (maximum latency difference [MLD], 8-cm latency [S8], and 14-cm latency [S14]) in 2334 hands of industrial workers, workers' compensation patients, and students. The MLD was determined by the centimetr... |
0 | Does Implant Insertion with a Funnel Decrease Capsular Contracture? A Preliminary Report | Reduction Mammoplasty for Female Breast Hypertrophy | BACKGROUND: Capsular contracture remains a common and dreaded complication of breast augmentation. The etiology of capsular contracture is believed to be multi-factorial, and its causes may include biofilm formation due to implant/pocket contamination with skin flora. It has been shown that insertion funnel use reduces... |
0 | Osteotome Sinus Floor Elevation Technique Without Grafting Material and Immediate Implant Placement in Atrophic Posterior Maxilla: Report of 2 Cases | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | Purpose: This case report discusses 2 patients who required implant placement in the atrophic posterior maxilla to support a fixed prosthesis with the least invasive and shortest procedure. Materials and Methods: The reference standard of care would be to perform sinus augmentation with an autologous bone graft through... |
0 | Treatment of focal articular cartilage defects in the knee: a systematic review | Diagnosis and Treatment of Osteochondritis Dissecans AUC | We asked whether autologous chondrocyte implantation or osteochondral autograft transfer yields better clinical outcomes compared with one another or with traditional abrasive techniques for treatment of isolated articular cartilage defects and whether lesion size influences this clinical outcome. We performed a litera... |
0 | Human sodium iodide symporter (hNIS) in fibroadenoma breast--a immunohistochemical study | Reduction Mammoplasty for Female Breast Hypertrophy | Human sodium iodide symporter (hNIS), responsible for the active transport of iodine is an integral plasma membrane glycoprotein present in the thyroid cells and extrathyroid tissues like breast and salivary glands. If its functional form is unequivocally shown in benign or malignant breast tissues, then it may serve a... |
0 | Working after a metastatic cancer diagnosis: Factors affecting employment in the metastatic setting from ECOG-ACRIN's Symptom Outcomes and Practice Patterns study | MSTS 2022 - Metastatic Disease of the Humerus | BACKGROUND Improved survival for individuals with metastatic cancer accentuates the importance of employment for cancer survivors. A better understanding of how metastatic cancer affects employment is a necessary step toward the development of tools for assisting survivors in this important realm. METHODS The ECOG-ACRI... |
0 | Radiolunate and radioscapholunate arthrodesis | Distal Radius Fractures | Eleven patients underwent radiocarpal arthrodesis for a wrist disease other than rheumatoid arthritis. Operations included seven radiolunate fusions and four radioscapholunate fusions. The indication for surgery was posttraumatic changes secondary to radius fracture (five), Kienbock's disease (three), localized arthrit... |
0 | The "Spinal Metastasis Invasiveness Index": A Novel Scoring System to Assess Surgical Invasiveness | MSTS 2022 - Metastatic Disease of the Humerus | STUDY DESIGN: Retrospective review.
OBJECTIVE: The aim of this study was to develop a surgical invasiveness index for metastatic spine tumor surgery (MSTS) that can serve as a standardized tool in predicting intraoperative blood loss and surgical duration; for the purpose of ascertaining resource requirements and aidin... |
0 | Abdominal compartment syndrome | DOD - Acute Comp Syndrome CPG | OBJECTIVE: To invstigte the physiologic effects and therapeutic management ofthe abdominal kompartm sendrome (ACS) METHODS: A review ofthe recent Iiterature, experiences and opinions ofthe author are expressed in the papei:
RESULTS AND CONCLUSIONS: Intraabdominal bleeding, peritonitis, ileus, shock-reperfusion syndrome... |
0 | Update on calcium pyrophosphate deposition | OAK 3 - Non-arthroplasty tx of OAK | Calcium pyrophosphate crystal deposition (CPPD) associates with ageing, osteoarthritis (OA), uncommon metabolic diseases, mutations and polymorphisms in the ankylosis human gene (ANKH). CPPD is frequently polyarticular, occurs due to a generalised articular predisposition, and the association between CPPD and OA is joi... |
0 | Principles of bone and joint disease control programs--osteoporosis | HipFx Supplemental Cost Analysis | During the past decade osteoporosis has emerged as a major public health problem. In societies with aging populations, an increasing number of persons are at risk of fracture, the most detrimental outcome of osteoporosis. Osteoporosis was initially identified as a problem of westernized countries, but a rising number o... |
0 | Definition of pertinent parameters for the evaluation of articular cartilage repair tissue with high-resolution magnetic resonance imaging | Diagnosis and Treatment of Osteochondritis Dissecans AUC | To evaluate articular cartilage repair tissue after biological cartilage repair, we propose a new technique of non-invasive, high-resolution magnetic resonance imaging (MRI) and define a new classification system. For the definition of pertinent variables the repair tissue of 45 patients treated with three different te... |
0 | Arthrodesis of the knee: Indications and treatment options | Surgical Management of Osteoarthritis of the Knee CPG | Arthrodesis as a salvage procedure remains a durable, time-proven technique for treatment of sepsis, tumor, failed arthroplasty, and the flail limb. It should be performed selectively, especially in light of modern arthroplasty and the increasingly favorable results of 2-stage reimplantation for the failed septic total... |
0 | Continuous passive motion and its effects on knee flexion after total knee arthroplasty in patients with knee osteoarthritis | OAK 3 - Non-arthroplasty tx of OAK | PURPOSE: This study evaluated the effects of continuous passive motion (CPM) on accelerated flexion after total knee arthroplasty (TKA) and whether CPM application measures (i.e. initial angle and daily increment) are associated with functional outcomes. METHODS: A retrospective investigation was conducted at the rehab... |
1 | The value of high resolution CT in the diagnosis of meniscal lesions of the knee | AMP (Acute Meniscal Pathology) | We report on 50 patients who had meniscal pathology and were given computed tomographic (CT) scans. Our diagnostic accuracy was approximately 92%. We believe that CT is a good method of screening these patients prior to using a much more expensive method, such as magnetic resonance imaging or diagnostic arthroscopy. |
0 | Cortical comminution in distal radial fractures can predict the radiological outcome: a cohort multicentre study | Distal Radius Fractures | This paper investigates whether cortical comminution and intra-articular involvement can predict displacement in distal radius fractures by using a classification that includes volar comminution as a separate parameter. A prospective multicentre study involving non-operative treatment of distal radius fractures in 387 ... |
1 | Arthroscopic lateral meniscectomy in adults with stable knees. A medium term evaluation of the results and a comparison with similar lesions of the medial meniscus | AMP (Acute Meniscal Pathology) | The results obtained in 37 cases of arthroscopic meniscectomy in isolated lesions of the lateral meniscus in adult patients are analysed. Isolated lesions were chosen as it is our belief that the results may be considerably influenced by the presence of ligamentous lesions. After an average follow-up of 33 months the r... |
0 | Minimal incision protocols for anesthesia, pain management, and physical therapy with standard incisions in hip and knee arthroplasties: the effect on early outcomes | Surgical Management of Osteoarthritis of the Knee CPG | Dramatic early outcomes with "minimal incision" surgery are attributed to patient selection, perioperative management, and the surgical procedure. This study was one on 50 patients in a single surgeon's practice who underwent total hip and total knee arthroplasties with standard incisions. The first 25 patients had sta... |
1 | Does an Injection of Adipose-Derived Mesenchymal Stem Cells Loaded in Fibrin Glue Influence Rotator Cuff Repair Outcomes? A Clinical and Magnetic Resonance Imaging Study | Trial Systematic Review Project | BACKGROUND: The mesenchymal stem cell (MSC)-based tissue engineering approach has been developed to improve the treatment of rotator cuff tears. Hypothesis/Purpose: The purpose was to determine the effect of an injection of adipose-derived MSCs loaded in fibrin glue during arthroscopic rotator cuff repair on clinical o... |
1 | MRI of early symptomatic metal-on-metal total hip arthroplasty: a retrospective review of radiological findings in 20 hips | Developmental Dysplasia of the Hip CPG | AIM: To perform a retrospective review of all the conventional radiographic and magnetic resonance imaging (MRI) studies performed in patients with early postoperative pain following cobalt-chrome metal-on-metal total hip arthroplasty. METHODS: A retrospective review of the radiology, surgical findings and histology in... |
0 | Biplanar Technique for Breast Implant Replacement through Mastectomy Scar | Acellular Dermal Matrix | BACKGROUND: Implant-based breast reconstruction is the most commonly used modality for breast reconstruction. A 2-stage reconstruction is employed when the skin envelope is insufficient. In the first stage, a tissue expander is placed in a pocket created beneath the pectoralis major muscle and an acellular dermal matri... |
1 | The adequacy of limb escharotomies-fasciotomies after referral to a major burn center | DOD - Acute Comp Syndrome CPG | To determine the frequency of inadequate decompression and its complications, the medical records of 108 pediatric burn patients requiring escharotomies or fasciotomies were reviewed. Of 108 patients, 100 (93%) had escharotomies or fasciotomies performed at an outlying facility before transfer. Of these 100 patients, 4... |
0 | Bisphosphonates induce apoptosis of circulating endothelial cells in multiple myeloma patients and in subjects with bisphosphonate-induced osteonecrosis of the jaws | MSTS 2018 - Femur Mets and MM | Bisphosphonates (BPs) are the current standard of care for bone lesions in patients with multiple myeloma (MM) but they are associated with a number of side effects such as osteonecrosis of the jaw. The exact mechanisms of osteonecrosis are not elucidated, and its physiopathology is based on several hypotheses such as ... |
0 | Enzyme replacement therapy in mucopolysaccharidosis VI (Maroteaux-Lamy syndrome) | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Objectives: To evaluate the safety and efficacy of weekly treatment with human recombinant N-acetylgalactosamine 4-sulfatase (rhASB) in humans with mucopolysaccharidosis type VI (MPS VI). Study design: An ongoing Phase I/II, randomized, two-dose, double-blind study. Patients were randomized to weekly infusions of eithe... |
0 | Cryotherapy Treatment After Unicompartmental and Total Knee Arthroplasty: A Review | OAK 3 - Non-arthroplasty tx of OAK | BACKGROUND: Cryotherapy is widely utilized to enhance recovery after knee surgeries. However, the outcome parameters often vary between studies. Therefore, the purpose of this review is to compare (1) no cryotherapy vs cryotherapy; (2) cold pack cryotherapy vs continuous flow device cryotherapy; (3) various protocols o... |
0 | Metal-on-metal total hip resurfacing arthroplasty in the presence of extra-articular deformities or implants | Management of Hip Fractures in the Elderly | BACKGROUND: Hip resurfacing has been proposed as an alternative to total hip replacement in patients who have proximal femoral deformities or retained hardware in the proximal aspect of the femur. In these situations, placement of a conventional stemmed hip prosthesis would be difficult or impossible, possibly necessit... |
0 | Difficulty of diagnosing the origin of lower leg pain in patients with both lumbar spinal stenosis and hip joint osteoarthritis | AAHKS (9/10) Regional Nerve Blocks | STUDY DESIGN: Case series.
OBJECTIVE: To present the difficulty of diagnosing the origin of lower leg pain in patients with lumbar spinal stenosis and hip joint arthritis.
SUMMARY OF BACKGROUND DATA: Pain arising from a degenerated hip joint is sometimes localized to the lower leg. Patients with lumbar spinal disease m... |
0 | Cost effectiveness of alendronate (fosamax(registered trademark)) for the treatment of osteoporosis and prevention of fractures | Management of Hip Fractures in the Elderly | Background: The Fracture Intervention Trial (FIT) demonstrated that the bisphosphonate alendronate reduces the risk of hip, spine and wrist fracture in osteoporotic women by approximately one half. Objective: To use data from FIT to conduct a cost-effectiveness analysis of alendronate. Design: A Markov model was develo... |
0 | Male osteoporosis: Clinical approach and management in family practice | Hip Fx in the Elderly 2019 | You were surprised to find Mr Roger Lee struggling into your polyclinic consultation room. Although he is 85 years old, Roger has always been healthy and spirited. That morning, he had slipped on the wet floor of his toilet at home and was now experiencing severe, persistent pain on his lower back. You performed an X-r... |
0 | Management of treatment-related adverse events in patients with multiple myeloma | MSTS 2018 - Femur Mets and MM | The introduction of novel antimyeloma therapies, including thalidomide, lenalidomide and bortezomib, has expanded treatment options for patients with multiple myeloma. These compounds alter the natural history of multiple myeloma and help improve outcomes, but have different and specific toxicity profiles. The major ad... |
0 | Inferior Outcome after Unstable Trochanteric Fracture Patterns Compared to Stable Fractures in the Elderly | Hip Fx in the Elderly 2019 | BACKGROUND: Various risk factors affecting outcome of elderly patients after proximal femur fracture have been identified. The present study aims to evaluate the impact of the fracture pattern in trochanteric fractures on postoperative mobility and complications.
METHODS: Ninety-two patients with a mean age of 84 years... |
0 | Avascular necrosis of femoral head: A short review | AAHKS (2) Corticosteroids | Avascular necrosis of femoral head (AVNFH) is the most common cause of hip joint destruction leading to hip replacement in Hong Kong. Steroids and alcohol are the two most common causes of AVNFH. Management of this painful and progressive situation in its early stages remains a controversial subject; but when the painf... |
0 | Management of non-traumatic acute limb ischemia and predictors of outcome in 270 thrombembolectomy cases | DoD LSA (Limb Salvage vs Amputation) | AIM: Acute limb ischemia (ALI) is one of the most potentially devastating but treatable diseases, resulting from a sudden obstruction in the arterial flow. The aim of this study was to examine the outcome of thromboembolectomy, and to determine the risk factors associated with limb loss and mortality in ALI. METHODS: A... |
0 | Exertional compartment syndrome of the upper extremity | DOD - Acute Comp Syndrome CPG | Exertional compartment syndrome is characterized by intracompartmental pressures that rise transiently following repetitive motion or exercise, thereby producing temporary, reversible ischemia, pain, weakness, and, occasionally, neurologic deficits. The exact cause or pathogenesis remains unclear; a disturbance of micr... |
0 | Elbow injuries in the young athlete - An orthopedic perspective | The Treatment of Pediatric Supracondylar Humerus Fractures AUC | Elbow injuries in young athletes are increasing with these athletes specializing in a single sport at an early age and participating in their chosen sport at a high level year-round. The majority of these injuries occur from valgus loading of the elbow, either repetitively causing an overuse injury or more acutely resu... |
0 | High 10-year survival rate with an anatomic cementless stem (SPS) | Management of Hip Fractures in the Elderly | BACKGROUND: Proximal cementless fixation using anatomic stems reportedly increases femoral fit and avoids stress-shielding. However, thigh pain was reported with the early stem designs. Therefore, a new anatomic cementless stem design was based on an average three-dimensional metaphyseal femoral shape. However, it is u... |
0 | All-cause mortality rates of hip fractures treated in the VHA: do they differ from Medicare facilities? | HipFx Supplemental Cost Analysis | PURPOSE: To estimate the 1-year all-cause mortality rates for hip fracture (HFx) patients hospitalized at Veterans Health Administration (VHA) facilities and compare with previous published mortality rates for veterans treated in Medicare facilities. METHODS: In total, 7 years of VHA discharge data on HFxs for 12,539 p... |
1 | Deep skin slough following skin traction for hip fractures | Management of Hip Fractures in the Elderly | INTRODUCTION: Elderly patients who fracture their hips are susceptible to complications associated with bed rest before surgery. In some institutions a skin traction device is used in order to relieve pain before surgery. The authors followed ten patients who developed severe (deep) skin slough and evaluated the relati... |
0 | Normal values of median nerve cross-sectional area obtained by ultrasound along its course in the arm with electrophysiological correlations, in 100 Asian subjects | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Introduction: The objective of this study is to obtain normative cross-sectional area (CSA) values for median nerve by ultrasound at predetermined sites and correlate them with electrophysiological variables in healthy Asian subjects. Methods: The median nerve was examined ultrasonographically in 100 healthy volunteers... |
0 | Municipality-based physical rehabilitation after acute hip fracture surgery in Denmark | Hip Fx in the Elderly 2019 | INTRODUCTION: Patients who are surgically treated for an acute hip fracture in Denmark commence early in-hospital physical rehabilitation (PR) with more than 95% of patients referred to further PR following discharge. However, the specifics of the PR services after discharge are unknown. Thus, the aim of the present pa... |
1 | Posterolateral bone graft of the tibia | DoD LSA (Limb Salvage vs Amputation) | A series of 30 high-energy tibial diaphyseal fractures in 30 patients were treated with posterolateral bone grafting (1984-1987). All of the fractures were open, a majority being Gustillo Type III with significant soft-tissue injury, comminution, or segmental bone loss. The common mechanisms of injury included motorcyc... |
0 | The knee adduction angle of the osteo-arthritic knee: A comparison of 3D supine, static and dynamic alignment | Surgical Management of Osteoarthritis of the Knee CPG | BACKGROUND: End-stage knee osteoarthritis (OA) commonly results in knee arthroplasty. Three dimensional (3D) supine imaging is often used for pre-operative planning to optimise post-operative knee adduction angles (KAA). However, supine imaging may not represent loaded knee alignment. The aim of this study was to inves... |
0 | Effect of neurotrophic factor, MDP, on rats' nerve regeneration | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Our objective was to determine the immune-modulating effects of the neurotrophic factor N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP) on median nerve regeneration in rats. We used male Wistar rats (120-140 days of age, weighing 250-332 g) and compared the results of three different techniques of nerve repair: 1) epineu... |
0 | Prognostic factors in limited-stage small cell lung cancer of patients treated with combined modality approach | MSTS 2022 - Metastatic Disease of the Humerus | PURPOSE: To evaluate the combined modality treatment results of patients with limited-stage small cell lung cancer (SCLC), who were treated and followed by the DELCSG.
PATIENTS AND METHODS: Sixty-three patients with limited-stage SCLC diagnosed between April 1991 and December 2002 were included. All patients were treat... |
0 | Lenalidomide maintenance after first-line therapy for high-risk chronic lymphocytic leukaemia (CLLM1): final results from a randomised, double-blind, phase 3 study | DoD SSI (Surgical Site Infections) | Background The combined use of genetic markers and detectable minimal residual disease identifies patients with chronic lymphocytic leukaemia with poor outcome after first-line chemoimmunotherapy. We aimed to assess lenalidomide maintenance therapy in these high-risk patients. Methods In this randomised, double-blind, ... |
0 | Primary total hip arthroplasty versus internal fixation in displaced fracture of femoral neck in sexa- and septuagenarians | DoD SSI (Surgical Site Infections) | Background: The optimal treatment of femoral neck fracture in the elderly patient is still under debate. In patients aged 60–80 years, the decision between internal fixation and arthroplasty remains controversial. The primary aim of the present study is to evaluate the functional outcome of patients aged 60–80 years wi... |
0 | Osteofascial compartment syndrome in the dog | DOD - Acute Comp Syndrome CPG | Experimentally induced osteofascial compartment syndrome (OFCS) has been reported in the craniolateral compartment of the canine crus. In this study, anatomic dissections and contrast radiographs were used to describe three additional osteofascial compartments in canine limbs. Experimental OFCS was produced in four dif... |
1 | Evaluation of blood pressure and heart rate in patients with hypertension who received tapentadol extended release for chronic pain: a post hoc, pooled data analysis | OAK 3 - Non-arthroplasty tx of OAK | BACKGROUND AND OBJECTIVES: Hypertension is one of the most common co-existing conditions in patients with chronic pain, and the potential effects of an analgesic on heart rate and blood pressure are of particular concern for patients with hypertension. The purpose of this analysis was to evaluate changes in blood press... |
0 | Rotationplasty in segmental resections of the femur | DoD SSI (Surgical Site Infections) | The authors report 26 cases of high-grade malignant tumors of the distal femur (23 osteosarcomas, 3 Ewing's tumors) submitted to rotation-plasty. The five-years actuarial survival rate (in the 23 cases of osteosarcoma) was 69% and there was no incidence of local recurrence. The following complications were observed: wo... |
0 | Eyebrow analysis after blepharoplasty in patients with brow ptosis | Upper Eyelid and Brow Surgery | Fifteen patients and 28 eyes with measurable eyebrow ptosis underwent standard upper eyelid blepharoplasty with or without sub-brow fat excision. The patients were educated about the status of their eyebrow position and the effects of either direct or indirect methods of brow elevation. The patients either refused or c... |
0 | Office management of weight loss in older persons | Management of Hip Fractures in the Elderly | Weight loss in older persons is associated with a variety of deleterious effects, including hip fracture, pressure ulcers, decreasing immune function, decreased functional status, and death. There are 4 major causes of weight loss: anorexia, sarcopenia, cachexia, and dehydration. Many of the reasons for the development... |
0 | Lateral Collagen Meniscus Implant (Menaflex): prospective European multicenter study with 2 year minimum follow-up | AMP (Acute Meniscal Pathology) | Purpose: Our purpose was to determine if Menaflex Collagen Meniscus Implants are safe and effective to treat loss of lateral meniscus tissue and if the implant functions whether or not tissue is missing at the popliteal hiatus. Methods and Materials: 60 patients with irreparable lateral meniscus tears or meniscus loss ... |
0 | Cosmetic surgery of the breast | Reduction Mammoplasty for Female Breast Hypertrophy | Plastic surgery of the breast is done in the following situations: Hypoplasia: The hypoplasia may vary from complete absence of breast tissue to a moderate amount of breast tissue. Hypertrophy: This is an extremely distressing problem to the patient and is always associated with some symptoms such as neckache, backache... |
0 | Intra-articular analgesia for arthroscopic meniscectomy | AMP (Acute Meniscal Pathology) | Intra-articular morphine has been shown to provide prolonged analgesia after arthroscopic knee surgery; the addition of local anaesthetic agents has been reported to improve this analgesic effect. Pethidine possesses local anaesthetic properties, and therefore this study was designed to evaluate its analgesic efficacy ... |
0 | Relationships between pain, function and radiographic findings in osteoarthritis of the knee: A cross-sectional study | OAK 3 - Non-arthroplasty tx of OAK | Objectives. The aim of this study was to investigate the relationships between pain, disability, and radiographic findings in patients with knee osteoarthritis (OA). Patients and Methods. A total of 114 patients with knee OA who attended the physical medicine and rehabilitation outpatient clinic were included in this s... |
1 | Repeat reduction mammaplasty | Reduction Mammoplasty for Female Breast Hypertrophy | Repeat reduction mammaplasty is an uncommonly performed procedure. Currently, no clear operative guidelines of management exist. Sixteen patients (28 breasts) with a mean age of 29 years (range, 13 to 52 years) underwent repeat breast reduction over an 11-year period. Before the first reduction, the mean notch to nippl... |
0 | Prospective, randomized trial of two antiseptic solutions for prevention of central venous or arterial catheter colonization and infection in intensive care unit patients | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | OBJECTIVES: To compare the efficacy of a newly available antiseptic solution (composed of 0.25% chlorhexidine gluconate, 0.025% benzalkonium chloride, and 4% benzyl alcohol), with 10% povidone iodine, on the prevention of central venous or arterial catheter colonization and infection. DESIGN: Prospective, randomized cl... |
0 | Liposuction | Panniculectomy & Abdominoplasty CPG | Liposuction, formally known as suction-assisted lipectomy, represents one of the most commonly performed aesthetic surgical procedures worldwide. Primarily a body contouring procedure, liposuction utilizes vacuum suction to remove subcutaneous adipose tissue in certain anatomical areas. Of note, liposuction should not ... |
0 | A triage strategy based on clinical risk factors for selecting elderly women for treatment or bone densitometry: the EPIDOS prospective study | Management of Hip Fractures in the Elderly | A triage strategy, based on a clinical hip fracture risk score, may be used to classify elderly women into three groups: one at high risk and requiring treatment, another needing further assessment by bone densitometry, and a third at low risk. We used prospective data from the EPIDOS study (7512 women older than 75 ye... |
0 | Heat-induced finger vasoconstriction controlled by skin sympathetic nerve activity | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Finger blood flow (BF) and skin sympathetic nerve activity (SSA) to the glabrous side of the hand were measured during immersion of the hand in a water bath in which temperature (T(w)) was raised every 10 min by steps of 2(degrees)C from 35 or 37 to 41(degrees)C. The experiments were conducted during the summer in room... |
0 | Hypercalcemia, Anemia, and Acute Kidney Injury: A Rare Presentation of Sarcoidosis | MSTS 2018 - Femur Mets and MM | We discuss a case of a 61-year-old woman who presented with substernal chest pain. She was found to have elevated calcium levels, anemia, and acute kidney injury. The hypercalcemia persisted despite therapy with fluids and bisphosphonates. She was found to have nonparathyroid hormone (PTH) mediated hypercalcemia. The c... |
0 | Loxoprofen: A Review in Pain and Inflammation | Glenohumeral Joint OA | Loxoprofen (Loxonin(), Loxonin() Pap, Loxonin() Tape) is a prodrug-type NSAID that is available in several formulations, including 60 mg tablets, 100 mg hydrogel patches and 50 or 100 mg tape. In active comparator-controlled trials, oral loxoprofen therapy (ranging from 2 days to 6 weeks' duration depending on the pain... |
0 | The sledge prosthesis 'model St. Georg' | Surgical Management of Osteoarthritis of the Knee CPG | This prosthesis was constructed in 1969 at the St. Georg Hospital in Hamburg, Germany, and has been used up to now in operations in 150 knees. The prosthesis is composed of 2 femoral sections in the form of sledges provided with notches with grooves which serve to anchor the sledge in the bone. The replacement of the t... |
1 | Debridement of Articular Cartilage: The Natural Course | OAK 3 - Non-arthroplasty tx of OAK | Chondral defects of the knee are quite common, affecting an estimated 10% to 12% of the population. Symptomatic chondral defects are thought to be persistent and possibly progressive. Less is known about the natural history of asymptomatic chondral lesions. Traditional treatment of chondral lesions has involved arthros... |
0 | Hospital cost of dislocation after primary total hip arthroplasty | HipFx Supplemental Cost Analysis | Background: The treatment of dislocation following primary total hip arthroplasty usually requires the use of expensive hospital resources and sometimes requires revision surgery. The hospital costs associated with treating this complication have not been previously analyzed, to our knowledge. The purpose of this study... |
0 | Cartilage-specific deletion of PPAR-gamma in mice results in early endochondral bone defects and accelerated aging-dependent development of osteoarthritis | Surgical Management of Osteoarthritis of the Knee CPG | Objectives: Long bones develop through a strict coordinated process of endochondral ossification within the growth plate resulting in the replacement of cartilage by bone and defect in this coordinated process may result in skeletal abnormalities such as dwarfism, kyphosis and also age-related defects such as osteoarth... |
0 | Tissue engineering of cartilage: do we need it, can we do it, is it good and can we prove it? | AMP (Acute Meniscal Pathology) | Current treatments of osteoarthritis (OA) focus on pain and loss of joint function. When these interventions fail, the destroyed joint is replaced by implants of metal, plastic and ceramics. In the future, we need to detect cartilage loss before it is too severe, prevent further loss and stimulate regrowth of lost cart... |
1 | Comparison of clinical outcomes with InterTan vs Gamma nail or PFNA in the treatment of intertrochanteric fractures: A meta-analysis | Hip Fx in the Elderly 2019 | Intertrochanteric fractures are common injuries in the elderly. Conventional intramedullary nails including Gamma 3 locking nail and proximal femoral nail antirotation (PFNA) were designed for unstable intertrochanteric fractures. The InterTan (IT) nail system, introduced in 2005, has been reported superior biomechanic... |
0 | Untreated osteochondritis dissecans of the femoral condyles: prediction of patient outcome using radiographic and MR findings | Diagnosis and Treatment of Osteochondritis Dissecans AUC | OBJECTIVE: We investigated the usefulness of plain film and MR findings in predicting the outcome of conservatively treated patients with femoral osteochondritis dissecans. DESIGN: Without knowledge of the clinical outcome, we retrospectively reviewed the initial plain films and MR examinations. Each MR examination was... |
1 | Two to five year results of primary ACL reconstruction using doubled tibialis anterior allograft | Anterior Cruciate Ligament Injuries CPG | The aim of the study was to report the 2-5 year results of primary ACL reconstruction with doubled tibialis anterior allograft. Seventy-three patients who underwent primary ACL reconstruction with doubled tibialis anterior allografts with minimum 2 year follow-up were included in the study. Sixty-four patients were ava... |
1 | Surgical treatment of metastatic fractures of the femur: a retrospective analysis of 142 patients | MSTS 2018 - Femur Mets and MM | BACKGROUND: Pathologic fractures of long bones are common complications of the metastatic disease; however, the influence of the primary tumor, the stage of metastatic disease, different surgical techniques, and the postoperative mobility on the postoperative survival has not been clearly defined. The aim of this retro... |
1 | A clinical and pharmacokinetic study of isolated limb perfusion with heat and melphalan for melanoma | MSTS 2018 - Femur Mets and MM | The pharmacokinetics of isolated limb perfusion were studied to see what melphalan concentrations were achieved and how efficient the isolation was. Twenty-eight patients received 32 limb perfusions with heat and melphalan for locally recurrent or level V melanoma. Melphalan was given 0.75 mg/kg for axillary/popliteal ... |
0 | Temporomandibular joint involvement in patients with multiple myelomaâ??a retrospective study | MSTS 2018 - Femur Mets and MM | Multiple myeloma (MM) is a common hematological malignancy that has widespread manifestations in multiple organs, including bones and joints. This retrospective study aimed to evaluate the involvement of the temporomandibular joint (TMJ) in patients with MM. Consecutive subjects with a diagnosis of MM who presented to ... |
0 | Biomechanical investigation of the type and configuration of screws used in high tibial osteotomy with titanium locking plate and screw fixation | AMP (Acute Meniscal Pathology) | BACKGROUND: To maintain the corrected alignment after high tibial osteotomy (HTO), fixation with titanium locking plate and screws is widely used in current practice; however, screw breakage is a common complication. Thus, this study was to investigate the mechanical stability of HTO with locking plate and various scre... |
0 | A Study to Evaluate the Effectiveness and Safety of Slow Release Hydromorphone HCL for Treatment of Patients With Osteoarthritis | OAK 3 - Non-arthroplasty tx of OAK | This was a phase 3, randomized (patients are assigned different treatments based on chance), placeboâ?controlled, doubleâ?blind, fixedâ?dose, parallelâ?group, multicenter study in adult patients with OA (osteoarthritis) who were unable to consistently control or treat their pain with nonopioid medications, or who h... |
0 | Coverage of distal radius internal fixation and wrist fusion devices with AlloDerm | Distal Radius Fractures | Dorsal plating for wrist arthrodesis, although a well-accepted form of treatment of the unstable or arthritic wrist, is accompanied by a high incidence of problems related to soft tissues. Dorsal plating of distal radius fractures has also been associated with soft-tissue complications, particularly extensor tendon rup... |
1 | Ambulatory continuous femoral analgesia for major knee surgery: A randomised study of ultrasound-guided femoral catheter placement | AAHKS (9/10) Regional Nerve Blocks | Needle-nerve stimulation has a false negative motor response rate, which may increase needle passes. This prospective, randomised study tested the hypothesis that femoral nerve catheters placed with ultrasound-only guidance could provide comparable postoperative analgesia to those placed using a conventional nerve stim... |
0 | Effects of bariatric surgery for knee complaints in (morbidly) obese adult patients: A systematic review | Panniculectomy & Abdominoplasty CPG | Obesity is a major risk factor for the development of knee osteoarthritis, and over the past 30 years the prevalence of obesity has more than doubled. In an advanced-stage knee osteoarthritis is treated with total knee arthroplasty, and the demand for primary total knee arthroplasties is expected to grow exponentially.... |
0 | Posterior medial meniscus detachment: a unique type of medial meniscal tear | Surgical Management of Osteoarthritis of the Knee CPG | Patients with posterior medial meniscal detachment, as determined at knee arthroscopy, were evaluated retrospectively. Mean follow-up was 5.3 years for 8 men and 20 women (30 knees; mean age, 57 years). Most patients had acute onset of pain with a minor specific incident. Seventeen patients were obese, 9 were overweigh... |
0 | Are biomechanical factors, meniscal pathology, and physical activity risk factors for bone marrow lesions at the knee? A systematic review | SR for PM on OA of All Extremities | OBJECTIVE: To systematically review the literature to determine whether biomechanical factors, meniscal pathology, and physical activity are risk factors for bone marrow lesions (BMLs) at the knee identified from magnetic resonance imaging in pre-osteoarthritis and osteoarthritis populations. METHODS: Electronic search... |
0 | 15 years of the histopathological synovitis score, further development and review: A diagnostic score for rheumatology and orthopaedics | AMP (Acute Meniscal Pathology) | The histopathological synovitis score evaluates the immunological and inflammatory changes of synovitis in a graduated manner generally customary for diagnostic histopathological scores. The score results from semiquantitative evaluation of the width of the synovial surface cell layer, the cell density of the stroma an... |
1 | Comparative efficacy of oral doses of clindamycin and erythromycin in the prevention of bacteraemia | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | Two antibiotics, clindamycin and erythromycin, were compared in a double-blind trial to test their efficacy in the prevention of post-dental extraction bacteraemia with streptococci in a group of 40 healthy patients. Tolerance to the oral doses was tested by questionnaire. Levels of drug in the serum were estimated usi... |
0 | The place of methotrexate perioperatively in elective orthopedic surgeries in patients with rheumatoid arthritis | AAHKS (2) Corticosteroids | No clear consensus exists on whether methotrexate (MTX) should be continued or whether this therapy should be discontinued for a few weeks in patients with rheumatoid arthritis (RA) undergoing surgery. Continued MTX therapy may impair wound healing, but discontinuation of the therapy may increase the risk of flares. In... |
0 | Use of external fixation for juxta-articular fractures in children | Distal Radius Fractures | In this article, the use of external fixation in the management of juxta-articular fractures in paediatric patients is discussed. Basic principles of Ilizarov technique are described for distal radial, distal femoral, distal humeral and distal tibial fractures. Common indications for external fixation in pediatric frac... |
0 | Effects of different molecular weight hyaluronan products on the expression of urokinase plasminogen activator and inhibitor and gelatinases during the early stage of osteoarthritis | AMP (Acute Meniscal Pathology) | Hyaluronan or hyaluronic acid (HA) has been used to treat osteoarthritic knees for more than 30 years. Here, we tested the hypothesis that HA with high molecular weight (MW) would have greater effects than HA with low MW on the expression of the plasminogen activator (PA)/plasmin system and gelatinases [matrix metallop... |
1 | Revision total knee arthroplasty with use of modular components with stems inserted without cement | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | We reviewed the results of seventy-six revision total knee replacements, performed between 1980 and 1988 on the Knee Service at The Hospital for Special Surgery, in seventy-four patients. Sixty-five patients (sixty-seven knees; 88 percent) had a complete clinical examination and radiographic evaluation, and nine patien... |
0 | Economic costs of obesity and inactivity | SR for PM on OA of All Extremities | PURPOSE: The purpose of this paper is to assess the economic costs of inactivity (including those attributable to obesity). These costs represent one summary of the public health impact of increasingly sedentary populations in countries with established market economies. Components of the costs of illness include direc... |
0 | Examining the role of transient receptor potential canonical 5 (TRPC5) in osteoarthritis | AMP (Acute Meniscal Pathology) | INTRODUCTION: Osteo-arthritis (OA) involves joint degradation and usually pain; with mechanisms poorly understood and few treatment options. There is evidence that the transient receptor potential canonical 5 (TRPC5) mRNA expression is reduced in OA patients' synovia. Here we examine the profile of TRPC5 in DRG and inv... |
1 | Femoral vessel injuries: analysis of factors predictive of outcomes | DoD SSI (Surgical Site Infections) | BACKGROUND: Femoral vessel injuries are the most common vascular injuries treated in a Level I trauma center. No studies have identified risk factors for survival and complications.
STUDY DESIGN: We performed a retrospective, 132-month study that included univariate and multivariate analyses.
RESULTS: We studied 204 pa... |
1 | Cutoff value of Japanese Orthopaedic Association shoulder score in patients with rotator cuff repair: Based on the University of California at Los Angeles shoulder score | Trial Systematic Review Project | BACKGROUND: The Japanese Orthopaedic Association shoulder score cutoff values were calculated in patients with rotator cuff repair using the University of California at Los Angeles shoulder score.
METHODS: Overall, 175 patients with rotator cuff repair were subjects in this study. The University of California at Los An... |
0 | Positioning of the surgical patient | DOD - Acute Comp Syndrome CPG | The positioning of the surgical patient has many implications for the patient. Cardiorespiratory physiology can be affected greatly by premorbid patient conditions, particularly diabetes mellitus, ischaemic heart disease, peripheral vascular disease, obesity and respiratory disease. After taking into account these fact... |
0 | Meniscal Root Tears | AMP (Acute Meniscal Pathology) | Meniscus root tears are a specific type of meniscal injury that have gained attention over the past 5 years and have been reported to account for 10% to 21% of all meniscal tears, affecting nearly 100,000 patients annually. Meniscal root tears either are defined as an avulsion of the insertion of the meniscus attachmen... |
0 | Long-Term Outcomes of Liner Cementation into a Stable Retained Shell: A Concise Follow-up of a Previous Report | Hip Fx in the Elderly 2019 | Liner cementation into a preexisting stable socket may reduce the morbidity of revision hip arthroplasty and preserve acetabular bone. However, the long-term outcomes of this technique remain unknown. The purpose of this report was to analyze the long-term results of a previously reported cohort of patients. Cementatio... |
1 | Return to work after lower limb amputation | DoD PRF (Psychosocial RF) | This study investigated the proportion of patients who returned to work following amputation and the factors that influenced a positive or negative outcome. One hundred patients of working age who had sustained unilateral lower limb amputation at least 1 year previously and who were established prosthesis users partici... |
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