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Negative pressure pulmonary edema in healthy cosmetic surgery patients
Panniculectomy & Abdominoplasty CPG
Anesthetic complications are uncommon in young and healthy patients undergoing cosmetic surgery. We report 2 cases of negative pressure pulmonary edema (NPPE) in young patients, 1 who underwent rhinoplasty and another who underwent augmentation mammaplasty and suction-assisted lipoplasty of the thighs and buttocks This...
1
One half of patients reports persistent pain three months after orthopaedic surgery
AMP (Acute Meniscal Pathology)
OBJECTIVE: To determine persistent post-surgical pain prevalence after orthopaedic surgery with its impact on patient quality of life and to assess factors related to it. STUDY DESIGN: Cross-sectional cohort study. PATIENTS: A questionnaire was mailed to 2100 patients undergoing orthopaedic surgery in our teaching hosp...
0
Classification criteria and severity assessment in work-associated upper extremity disorders: Methods matter
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Work-associated musculoskeletal disorders of the upper extremity are common and disabling. Research on these disorders is needed and requires valid methods of classification of the disorders for epidemiologic studies and measurement of their impact on functional status. This commentary discusses the methodologic aspect...
0
Altered Wnt and NF-kappaB Signaling in Facet Joint Osteoarthritis: Insights from RNA Deep Sequencing
TO: WNT2 Pathway Modulator
Facet joint osteoarthritis is common lumbar osteoarthritis characterized by facet joint cartilage degeneration. However, the molecular basis of facet joint osteoarthritis remains largely undetermined. In the current study, we collected facet joint tissue samples from 10 control patients and 48 patients with facet joint...
0
Lactase gene c/t(-13910) polymorphism, calcium intake, and pQCT bone traits in Finnish adults
Distal Radius Fractures
Genetic lactase nonpersistence may influence calcium intake and thereby bone health. We investigated in the Cardiovascular Risk in Young Finn Study whether young adults aged 31-46 years with the C/C(-13910) genotype are more susceptible to reduced bone phenotypes, low-energy fractures, and low calcium intake than subje...
0
The Use of Continuous Wound Infusion Analgesia in Total Knee Arthroplasty
AAHKS (8) Anesthetic Infiltration
Continuous local wound infusion analgesia is a relatively new way of managing post�operative pain, whereby a local anesthetic is continuously infused into the surgical area. Some studies and users have reported decreased pain, decreased opioid use, decreased post�operative nausea and vomiting, decreased length of s...
0
Cross-sectional study of pain and disability at knee replacement surgery for osteoarthritis in 299 patients
Surgical Management of Osteoarthritis of the Knee CPG
OBJECTIVE: To evaluate pain and disability at the time of knee replacement surgery for osteoarthritis. METHODS: In this multicenter cross-sectional study, 299 patients at 12 orthopedic surgery centers in Lyon, France were evaluated on the day before knee replacement surgery. Pain severity was assessed on a visual analo...
1
Discoid Lateral Meniscus
AMP (Acute Meniscal Pathology)
PURPOSE OF REVIEW: Discoid lateral meniscus (DLM) is a well-known meniscus variant, and comprises excess and thickened meniscal tissue, altered collagen ultrastructure, and peripheral instability. This article presents a comprehensive review on current knowledge of DLM, focusing on pathology in parallel with surgical t...
0
Arthrodesis in the charcot foot: A systematic review
DoD SSI (Surgical Site Infections)
The Charcot foot is a condition characterized by a progressive derangement of the foot. The type of deformity and patient clinical conditions will lead to the proper surgical approach among exostectomy, arthrodesis (through external and/or internal fixation) and amputation. Many authors report good clinical outcomes pe...
0
Galactosemia: A treatable metabolic disorder
Patrick’s pharmacoepidemiology project
Galactosemia is a rare metabolic disorder. It has good prognosis, if detected in neonatal period or early infancy. Two cases of classic galactosemia are presented. One case was detected in neonatal period. Early intervention has led to normal development till now. The second case was diagnosed at 1 year of age. Elimina...
0
Serum IgG reactive with oral anaerobic microorganisms associated with infections of endodontic origin
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
Numerous species of bacteria have been implicated with infections of endodontic origin. The purpose of this study was to compare the levels of serum IgG antibodies reactive with a panel of 10 oral anaerobic microorganisms implicated in infections of endodontic origin. Serum samples were collected from 4 patient groups ...
0
High fracture probability with FRAX(registered trademark) usually indicates densitometric osteoporosis: Implications for clinical practice
Management of Hip Fractures in the Elderly
Summary Most patients designated as high risk of fracture using fracture risk assessment tool (FRAX(registered trademark)) with femoral neck bone mineral density (BMD) (i.e., 10-year major osteoporotic fracture probability exceeding 20% or hip fracture exceeding 3%) have one or more T-scores in the osteoporotic range; ...
0
Adaptation of Turkish version of the questionnaire Quick Disability of the Arm, Shoulder, and Hand (Quick DASH) in patients with carpal tunnel syndrome
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
The aim of this study was to assess the reliability and validity of the Turkish version of the Quick Disability of the Arm, Shoulder, and Hand (Quick DASH) scale in patients with carpal tunnel syndrome (CTS). Sixty nine patients with idiopathic CTS were included. The Quick DASH questionnaire consists of three subscales...
0
Instrumented gait analysis in patients with medial osteoarthritis of the knee after mobile-bearing unicompartmental knee arthroplasty
OAK 3 - Non-arthroplasty tx of OAK
Background: Unicompartmental knee arthroplasty (UKA) is an effective treatment for patients with medial osteoarthritis of the knee joint. Instrumented gait analysis provides an objective measure to quantify and qualify postoperative changes of gait. The purpose of this study was to evaluate standardized instrumented ga...
0
The cost of fall related presentations to the ED: a prospective, in-person, patient-tracking analysis of health resource utilization
HipFx Supplemental Cost Analysis
We prospectively collected data on elderly fallers to estimate the total cost of a fall requiring an Emergency Department presentation. Using data collected on 102 falls, we found the average cost per fall causing an Emergency Department presentation of $11,408. When hospitalization was required, the average cost per f...
1
Analgesia after total knee replacement: local infiltration versus epidural combined with a femoral nerve blockade: a prospective, randomised pragmatic trial
AAHKS (9/10) Regional Nerve Blocks
In a randomised controlled pragmatic trial we investigated whether local infiltration analgesia would result in earlier readiness for discharge from hospital after total knee replacement (TKR) than patient-controlled epidural analgesia (PCEA) plus femoral nerve block. A total of 45 patients with a mean age of 65 years ...
1
High healing rate of stable femoral condyle osteochondritis dissecans in young patients placed in a hinged knee brace locked in extension: a retrospective study
Osteochondritis Dissecans 2020 Review
We report the rate of stable femoral condyle osteochondritis dissecans (OCD) lesion healing in adolescents using a locked hinged knee brace for a minimum of 6 weeks or until pain free, followed by physical therapy. Patients aged 5-18 at the time of a primary diagnosis of femoral condyle OCD were reviewed. Patients who ...
0
Side effects during continuous epidural infusion of morphine and fentanyl
Surgical Management of Osteoarthritis of the Knee CPG
Respiratory effects, nausea, somnolence, and pruritus were compared during a 48-hr period of continuous epidural morphine (n = 34) and fentanyl (n = 32) infusion in 66 patients following elective total replacement of the hip or knee joint. Respiratory effects were assessed by PaCO2. Side effects were assessed by visual...
0
Abnormal achromatic and chromatic contrast sensitivity in neurofibromatosis type 1
Upper Eyelid and Brow Surgery
PURPOSE: Neurofibromatosis type 1 (NF1) is a monogenic disorder with the majority of patients presenting subtle to moderate cognitive impairments. Visuospatial deficits are considered to be one of the hallmark characteristics of their cognitive profile. However, low-level visual processing has not been previously inves...
0
Short-term radiographic result of cementless hemiarthroplasty using tapered wedge-shaped femoral component in older patients with femoral neck fractures
Hip Fx in the Elderly 2019
Objective: To evaluate the short-term radiographic results of cementless hemiarthroplasty using a tapered wedge-shaped femoral component in elderly patients with displaced femoral neck fracture. Specifically, the authors assessed the prevalence of intraoperative crack and rate of subsidence associated with tapered wedg...
0
Oral–Gut Microbiota, Periodontal Diseases, and Arthritis: Literature Overview on the Role of Probiotics
AMP (Acute Meniscal Pathology)
Periodontal diseases are oral inflammatory diseases affecting the tissues supporting and surrounding the teeth and include gingivitis and periodontitis. Oral pathogens may lead to microbial products spreading into the systemic circulation and reaching distant organs, while periodontal diseases have been related to low-...
1
The associations between cognitive dysfunction, stress biomarkers, and administered anesthesia type in total knee arthroplasties: Prospective, randomized trial
AAHKS (9/10) Regional Nerve Blocks
Background: Postoperative cognitive dysfunction (POCD) is a serious complication associated with total knee arthroplasty (TKA) and has been shown to increase the length of hospital stay, cause functional impairment, and morbidity. Objectives: We aimed to determine whether POCD is associated with the use of general or r...
0
Extra-articular distal radius malunion: The phosphate cement alternative
Distal Radius Fractures
UNLABELLED: Five consecutive patients (mean age: 40.4 yrs (range, 19-58 yrs)), with symptomatic distal radius malunion underwent corrective opening wedge osteotomy using phosphate cement as an alternative to bone autograft, at a mean 9 months (4-16mo) of fracture. Internal fixation used a plate placed just above the di...
0
Geriatric consultation in elderly hip fracture patients
Management of Hip Fractures in the Elderly
Introduction.- To assess the effects of the assignment of a part-time geriatric consultant to the trauma unit of the Hospital of Segovia for patients over 75 admitted for surgical treatment of hip fracture. Methods.- Control group (188 patients admitted in 2007 received traditional care) was compared with intervention ...
0
Gender-specific associations between soy and risk of hip fracture in the Singapore Chinese Health Study
Management of Hip Fractures in the Elderly
Although there is some epidemiologic evidence that soy may reduce risk of osteoporotic fracture in women, it is not known whether this risk reduction also occurs for men. The authors examined gender-specific associations between soy intake and hip fracture risk in the Singapore Chinese Health Study, a prospective cohor...
0
Analysis of hip dysplasia and spinopelvic alignment in cerebral palsy
Developmental Dysplasia of the Hip 2020 Review
BACKGROUND CONTEXT: Knowledge of sagittal spinopelvic parameters and hip dysplasia is important in cerebral palsy (CP) patients because these parameters differ from those found in the general population and can be related to symptoms. PURPOSE: The purpose of this study was to analyze sagittal spinopelvic alignment and ...
0
Posttraumatic elbow deformities in children
Pediatric Supracondylar Humerus Fracture 2020 Review
In the last 20 years 49 children with gross posttraumatic elbow deformities have been treated in our hospital: 19 patients with an overlooked radial head dislocation, 12 children with a radial condyle deformity and 19 patients with a severe radial head deformity. Secondary treatment: In the majority of cases secondary ...
0
Emerging role of long noncoding RNAs in recurrent hepatocellular carcinoma
Dental Implant Infection
Hepatocellular carcinoma (HCC) remains one of the most frequent types of liver cancer and is characterized by a high recurrence rate. Recent studies have proposed that long non-coding RNAs (lncRNAs) are potential biomarkers in several recurrent tumor types. It is now well understood that invasion, migration, and metast...
0
A National Multicenter Study on overall survival in elderly metastatic castrate-resistant prostate cancer patients treated with Radium-223
MSTS 2022 - Metastatic Disease of the Humerus
BACKGROUND: Radium-223 prolongs overall survival (OS) and delays time to the first symptomatic skeletal events in patients with symptomatic metastatic castration-resistant prostate cancer (mCRPC). There is a lack of evidence on the safety and efficacy of Radium-223 treatment in the very elderly population. AIMS: Aim of...
0
The Impact of Resident Postgraduate Year Involvement in Body-Contouring and Breast Reduction Procedures: A Comprehensive Analysis of 9638 Patients
Reduction Mammoplasty for Female Breast Hypertrophy
Given the rising popularity in body-contouring procedures (BCPs) in the United States, it is important to assess the currently unknown association between resident involvement and postoperative complications. As such, the aim of this study was to evaluate the impact of resident involvement on outcomes in BCPs using a l...
0
Activities of clotting, fibrinolytic, and anticoagulant components of plasma hemostasis in patients with degenerative diseases of large joints
OAK 3 - Non-arthroplasty tx of OAK
Analysis of plasma hemostasis parameters was carried out in 110 patients with degenerative diseases of hip or knee joints hospitalized for initial endoprosthetics. Molecular markers of clotting and fibrinolysis and physiological anticoagulants were studied. Activities of all components of plasma hemostasis were normal ...
0
The role of activity, adherence, and off-loading on the healing of diabetic foot wounds
DoD LSA (Limb Salvage vs Amputation)
The etiology of diabetic foot ulcerations is commonly associated with the presence of peripheral neuropathy and repetitive trauma due to normal walking activities to areas of the foot exposed to moderate or high pressure. The goal of any treatment plan should include as a central tenet the mitigation or modulation of t...
0
Nutritional issues in nursing home care
HipFx Supplemental Cost Analysis
The most common nutritional problems in nursing home residents are weight loss and concomitant protein energy undernutrition. Although the causes of weight loss in these patients can usually be treated, they are rarely identified in the nursing home. Depression and adverse drug effects are the most common causes of wei...
1
The use of bisphosphonates in patients with breast cancer
MSTS 2018 - Femur Mets and MM
BACKGROUND: Bone is the most common site of breast cancer metastases. Skeletal metastases may be associated with harmful and painful events such as fractures, spinal cord compression, and hypercalcemia. By inhibiting osteoclasts and bone resorption, bisphosphonates can interrupt the process of bone destruction and decr...
1
The effects of low level laser in clinical outcome and neurophysiological results of carpal tunnel syndrome
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
OBJECTIVES: Carpal tunnel syndrome (CTS) is the most common neuropathy that can be diagnosed with confidence by the nerve conduction study (NCS). One of the recent treatments of CTS is the application of low power laser (LPL) therapy. The present study evaluates the effects of LPL irradiation through NCS and clinical s...
1
Effect of an orally formulated processed black cumin, from Iranian traditional medicine pharmacopoeia, in relieving symptoms of knee osteoarthritis: A prospective, randomized, double-blind and placebo-controlled clinical trial
OAK 3 - Non-arthroplasty tx of OAK
AIM: Osteoarthritis is a global health problem, especially for the elderly. A good replacement for non-surgical treatments is the use of traditional medicines. We selected a revere plant (Nigella sativa L.), a widely utilized medicinal herb for the treatment of inflammatory conditions, from the Iranian traditional medi...
0
Patient-specific instrumentation for total shoulder arthroplasty: not as accurate as it would seem
Glenohumeral Joint OA
BACKGROUND: There is an increasing body of literature suggesting that the use of patient-specific instrumentation (PSI) in total shoulder arthroplasty (TSA) results in improved positioning of the glenoid component. The aim of this in vivo study was to assess the accuracy of PSI of the glenoid component in TSA in a cons...
0
A comparison of 0.2 and 0.5 mg intrathecal morphine for postoperative analgesia after total knee replacement
AAHKS (4) Acetaminophen
The optimal dose of intrathecal morphine for postoperative analgesia after major surgery is a matter of debate, with some uncertainty concerning the therapeutic potential and safety of intrathecal morphine in the dose range 0.3-1.0 mg. This randomised double-blind study compared the efficacy and side-effect profile of ...
0
Outcome of antimicrobial therapy in documented biofilm-associated infections: A review of the available clinical evidence
Dental Implant Infection
Numerous laboratory findings indicate that microbial biofilms may be encountered in several types of human infections, affecting the activity of antimicrobial agents. We evaluated the clinical evidence regarding the effectiveness of antimicrobial therapy for infections documented to be biofilm-associated, by performing...
0
Clinical characteristics and prognostic factors in Chinese patients with classical Hodgkin's lymphoma involving extranodal sites: a retrospective single-center
MSTS 2022 - Metastatic Disease of the Humerus
<b>Objectives</b>: To analyze the clinical characteristics and prognostic factors in Chinese patients with classical Hodgkin's lymphoma (cHL) involving extranodal sites. <b>Methods</b>: Clinical features and outcomes of 68 patients diagnosed with cHL involving extranodal sites from April 2003 to November 2017 were anal...
0
MRI detection of forearm soft tissue injuries with radial head fractures
Distal Radius Fractures
BACKGROUND: This study aims to evaluate the incidence of forearm soft tissue abnormalities associated with radial head fracture severity based on the Mason classification system. METHODS: Eighteen patients (age 18-45 years) were prospectively evaluated with elbow radiographs and magnetic resonance imaging (MRI) followi...
0
Combined circular external fixation and open reduction internal fixation with pro-syndesmotic screws for repair of a diabetic ankle fracture
DoD LSA (Limb Salvage vs Amputation)
The surgical management of ankle fractures among the diabetic population is associated with higher complication rates compared to the general population. Efforts toward development of better methods in prevention and treatment are continuously evolving for these injuries. The presence of peripheral neuropathy and the p...
1
Effect of surgical delay on bacterial colonization in proximal humeral fractures
DoD SSI (Surgical Site Infections)
Postoperative infection is a severe complication after proximal humeral fracture surgical treatment. The aim of this study was to determine if the surgical delay could modify the number and type of bacteria on the surgical site. A two stages study was set up. In the first stage the effect of delay was simulated in 20 p...
0
Avascular necrosis of the femoral head in sickle cell syndrome: a report of 5 cases
Diagnosis and Treatment of Osteochondritis Dissecans AUC
The course and management of avascular necrosis of the femoral head (AVNFH) in six hips of 5 sickle cell syndrome patients (3 with Hb SS, 1 with Hb SC and 1 with Hb S/beta+-thalassaemia) are described. Two patients (aged 13 and 17 years) presented with Perthes- and osteochondritis dessicans-type lesions. These hips pro...
0
Probabilistic Approach for Determining the Material Properties of Meniscal Attachments In Vivo Using Magnetic Resonance Imaging and a Finite Element Model
PJI DX Updated Search
The material properties of in vivo meniscal attachments were evaluated using a probabilistic finite element (FE) model and magnetic resonance imaging (MRI). MRI scans of five subjects were collected at full extension and 30 degrees , 60 degrees , and 90 degrees flexion. One subject with radiographic evidence of no knee...
0
Mesenteric visceral lipectomy using tissue liquefaction technology reverses insulin resistance and causes weight loss in baboons
Panniculectomy & Abdominoplasty CPG
BACKGROUND: Visceral obesity is associated with diabetogenic and atherogenic abnormalities, including insulin resistance and increased risk for cardiometabolic diseases and mortality. Rodent lipectomy studies have demonstrated a causal link between visceral fat and insulin resistance, yet human omentectomy studies have...
0
Efficacy of rapid maxillary expansion in children with obstructive sleep apnea syndrome: 36 months of follow-up
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
Purpose: In view of the positive outcome of orthodontic treatment using rapid maxillary expansion (RME) on sleep-disordered breathing, we generated data on RME in children with obstructive sleep apnea (OSA) by evaluating objective and subjective data over a 36-month follow-up period, to determine whether RME is effecti...
0
Menopause and Rheumatic Disease
OAK 3 - Non-arthroplasty tx of OAK
Menopause occurs naturally in women at about 50 years of age. There is a wealth of data concerning the relationship of menopause to systemic lupus erythematosus, rheumatoid arthritis, and osteoarthritis; there are limited data concerning other rheumatic diseases. Age at menopause may affect the risk and course of rheum...
0
Assessment of clinical risk factors to validate the probability of osteoporosis and subsequent fractures in Korean women
Management of Hip Fractures in the Elderly
This cross-sectional, observational study was designed to identify clinical risk factors of osteoporosis and fractures in Korean women to validate the probability of osteoporosis and subsequent fractures. A total of 1541 Korean women were recruited nationally. Fracture history of any site, risk factors of osteoporosis,...
0
Catastrophic failure after open reduction internal fixation of femoral neck fractures with a novel locking plate implant
Management of Hip Fractures in the Elderly
OBJECTIVES: To determine if the use of a novel proximal femoral locking plate could reduce the incidence of femoral neck shortening and improve clinical outcomes after open reduction internal fixation (ORIF) for femoral neck fractures as compared with historical controls. DESIGN: Single surgeon, retrospective case-cont...
0
Chronic kidney disease can increase the risk of preoperative deep vein thrombosis in middle-aged and elderly patients with hip fractures
Hip Fx in the Elderly 2019
Background: Preoperative deep vein thrombosis (DVT) is a common complication in patients with hip fractures. Chronic kidney disease (CKD) as a frequent comorbidity in middle-aged and elderly patients with hip fractures is known to promote a proinflammatory and prothrombotic state. We aimed to identify whether CKD can i...
0
Avascular necrosis of femoral head associated with connective tissue disease in Nigerians: Case series
PJI DX Updated Search
BACKGROUND: Avascular Necrosis (AVN) or osteonecrosis has been frequently reported among Nigerians with sickle cell disease. Other known aetiologies include connective tissue diseases, alcohol, fat embolism, juvenile arthritis and pregnancy. Connective tissue disease (CTD) are uncommonly reported among Nigerians. OBJEC...
0
Improving stability of elastic stable intramedullary nailing in a transverse midshaft femur fracture model: biomechanical analysis of using end caps or a third nail
Pediatric Diaphyseal Femur Fractures 2020 Review
BACKGROUND: Elastic stable intramedullary nailing (ESIN) is accepted widely for treatment of diaphyseal femur fractures in children. However, complication rates of 10 to 50 % are described due to shortening or axial deviation, especially in older or heavier children. Biomechanical in vitro testing was performed to dete...
0
A Survey of High- and Low-Energy Acetabular Fractures in Elderly Patients
Hip Fx in the Elderly 2019
Introduction: Geriatric patients represent 14% of acetabular fractures and are the fastest growing subset of patients affected by this injury in the US. Treatment outcomes have been reported as inferior to those achieved in younger patients after high-energy (HE) acetabular trauma. This study aimed to compare detailed ...
0
Circumstances of falls causing hip fractures in the elderly
Management of Hip Fractures in the Elderly
A prospective analysis was performed on 832 patients to determine the circumstances surrounding falls leading to hip fracture within a homogeneous, elderly urban population. Special emphasis was placed on the season of year, time of day, location of fall, and other circumstances in which the fracture occurred. All pati...
0
Clinical Considerations for the Use Lower Extremity Arthroplasty in the Elderly
AAHKS (2) Corticosteroids
There is an increase in the aging population that has led to a surge of reported cases of osteoarthritis and a greater demand for lower extremity arthroplasty. This article aims to review the current treatment options and expectations when considering lower extremity arthroplasty in the elderly patient with an emphasis...
0
Late Nontraumatic Dissociation of the Femoral Head and Trunnion in a Total Hip Arthroplasty
PJI DX Updated Search
Background. Modular total hip arthroplasties are increasingly popular because customisation allows optimal restoration of patient biomechanics. However, the introduction of component interfaces provides greater opportunities for failure. We present a case of late nontraumatic dissociation of the head-neck interface, mo...
1
Comparative study between computer assisted-navigation and conventional technique in minimally invasive surgery total knee arthroplasty, prospective control study
Surgical Management of Osteoarthritis of the Knee CPG
Background: Both Minimally Invasive surgery (MIS) and Computer-Assisted Surgery (CAS) are useful in Total Knee Arthroplasty (TKA). Minimally invasive total knee arthroplasty was associated with decreased blood loss, shorter hospital stays, and increased range of motion. Computer-assisted surgery in total knee arthropla...
0
Radiographic evaluation of Baumann angle in Chinese children and its clinical relevance
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
Normal Baumann angles in 98 children aged 2 to 13 years and abnormal Baumann angles in 71 children with supracondylar humeral fractures were evaluated. In healthy children, Baumann angles ranged from 64(degrees)to 80(degrees)(72.4(degrees)(plus or minus) 4.6(degrees)) in boys and from 65(degrees)to 81(degrees)(72.9(deg...
1
Changes in body heat during hip fracture surgery: a comparison of spinal analgesia and general anaesthesia
Management of Hip Fractures in the Elderly
Postoperative hypothermia initiates an increased oxygen demand in the postoperative period and may endanger patients with restricted cardiopulmonary reserves. In order to compare net heat losses and gains, we studied 28 women undergoing hip fracture surgery, using either general anaesthesia or spinal analgesia. The sup...
0
Pennsaid therapy for osteoarthritis of the knee: a systematic review and metaanalysis of randomized controlled trials
SR for PM on OA of All Extremities
OBJECTIVE: To systematically review published randomized controlled trials (RCT) evaluating a new topical diclofenac solution (Pennsaid) in patients with osteoarthritis (OA) of the knee. METHODS: RCT were identified by searching electronic data sources as well as by contact with the manufacturer of Pennsaid. Details of...
0
Intravenous Versus Oral Acetaminophen in Primary Total Hip Arthroplasty
AAHKS (2) Corticosteroids
This is a single center, prospective, randomized controlled study. 60 subjects will be recruited (see #6 Recruitment and Compensation below). On the day of surgery, subjects will be randomized to receive either the study intervention (intravenous acetaminophen and placebo tablets) or the control intervention (intraveno...
0
PPARG , atranscription factor, regulates cartilage/bone development and homeostasis through the PTEN-AKT pathway
Surgical Management of Osteoarthritis of the Knee CPG
Aims: Long bones develop through a strict coordinated process of endochondral ossification within the growth plate resulting in the replacement of cartilage by bone and defect in this coordinated process may result in skeletal abnormalities such as dwarfism, kyphosis and also agerelated defects such as osteoarthritis (...
0
Patient satisfaction after total knee arthroplasty is affected by their general physical well-being
Surgical Management of Osteoarthritis of the Knee CPG
Purpose: We hypothesise that patients with a worse post-operative generic physical health, and those with a subclinical improvement, will have a greater rate of dissatisfaction with their total knee arthroplasty (TKA) despite improvement in their knee function. Methods: Prospectively complied data for 2,330 primary TKA...
0
Single versus staged epidural injections of 0.75% bupivacaine: pharmacokinetic and pharmacodynamic effects
AAHKS (8) Anesthetic Infiltration
Epidural anesthesia may be performed as a single injection or by staged doses. Thirty patients undergoing primary total hip replacement were randomly assigned to have epidural anesthesia using a single injection or a staged technique with 25 mL of 0.75% bupivacaine. Arterial plasma bupivacaine concentrations were signi...
0
Admission of nursing home residents to a hospital internal medicine department
Management of Hip Fractures in the Elderly
Objective: Hospitalization of nursing home residents is costly and potentially exposes residents to iatrogenic disease and psychological harm. Design and Setting: In this study, we analyzed the data from the Basic Minimum Data Set of patients hospitalized from the nursing home who were discharged from all the internal ...
0
Current perspectives in mesenchymal stem cell therapies for osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
Osteoarthritis (OA) is a degenerative joint disease most commonly occurring in the ageing population. It is a slow progressive condition resulting in the destruction of hyaline cartilage followed by pain and reduced activity. Conventional treatments have little effects on the progression of the condition often leaving ...
0
Single institution early experience with the bundled payments for care improvement initiative
DoD SSI (Surgical Site Infections)
The Centers for Medicare &Medicaid Services (CMS) implemented the Bundled Payments for Care Improvement (BPCI) initiative in 2011. Through BPCI, organizations enlisted into payment agreements that include both performance and financial accountability for episodes of care. To succeed, BPCI requires quality maintenance a...
1
Treatment for displaced intracapsular fracture of the proximal femur. A prospective, randomised trial in patients aged 65 to 79 years
Hip Fx in the Elderly 2019
We performed a prospective, randomised trial comparing three treatments for displaced intracapsular fractures of the hip in 280 patients aged 65 to 79 years. The mean patient survival was significantly higher in the group undergoing reduction and internal fixation (79 months) compared with that with a cemented Thompson...
0
Load distribution in early osteoarthritis
AMP (Acute Meniscal Pathology)
Total knee replacement is an accepted standard of care for the treatment of advanced knee osteoarthritis with good results in the vast majority of older patients. The use in younger and more active populations, however, remains controversial due to concerns over activity restrictions, implant survival, and patient sati...
0
Making health care safer: a critical analysis of patient safety practices
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
OBJECTIVES: Patient safety has received increased attention in recent years, but mostly with a focus on the epidemiology of errors and adverse events, rather than on practices that reduce such events. This project aimed to collect and critically review the existing evidence on practices relevant to improving patient sa...
0
Estrogens: Protective or risk factors in brain function?
DoD PRF (Psychosocial RF)
Over the past century, the average lifespan of women has increased from 50 to over 80 years, but the age of the menopause has remained fixed at 51 years. This "change of life" is marked by a dramatic and permanent decrease in circulating levels of ovarian estrogens. Therefore, more women will live a greater proportion ...
0
Extra-articular Mimickers of Lateral Meniscal Tears
AMP (Acute Meniscal Pathology)
CONTEXT: Lateral meniscus tears are a common entity seen in sports medicine. Although lateral-side knee pain is often the result of a meniscus injury, several extra-articular pathologies share signs and symptoms with a meniscus tear. It is critical for the clinician to be able to identify and understand extra-articular...
0
Recovery, age, and gender effects on hand dexterity after a distal radius fracture. A 1-year prospective cohort study
Distal Radius Fractures
Study Design: A prospective cohort study. Introduction: Physical factors that predict hand dexterity and the recovery of hand dexterity after a distal radius fracture (DRF) have not yet been examined. Purpose of the Study: The first objective was to evaluate the recovery of hand dexterity comparing the injured and unin...
1
Outcome and structural integrity after arthroscopic rotator cuff repair using 2 rows of fixation: minimum 2-year follow-up
Optimizing the Management of Full-Thickness Rotator Cuff Tears
BACKGROUND: Although arthroscopic repairs of the rotator cuff are becoming increasingly popular, security of fixation remains a concern. Two-row repairs have been described, but clinical outcome reports have primarily involved open techniques. HYPOTHESIS: An arthroscopic repair technique that uses 2 rows of fixation pr...
1
Ultrasound plus low-level laser therapy for knee osteoarthritis rehabilitation: a randomized, placebo-controlled trial
OAK 3 - Non-arthroplasty tx of OAK
This study evaluated the synergistic effects of ultrasound (US) and low-level laser therapy (LLLT) with or without therapeutic exercises (TE) in women with knee osteoarthritis. Forty-two Caucasian women with knee osteoarthritis were allocated into three groups: (1) the placebo group who did not perform TE, but the prot...
0
The Glasgow Prognostic Score predicts poor survival in cisplatin-based treated patients with metastatic nasopharyngeal carcinoma
MSTS 2022 - Metastatic Disease of the Humerus
BACKGROUND: Several inflammation-based prognostic scoring systems, including Glasgow Prognostic Score (GPS), neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) have been reported to predict survival in many malignancies, whereas their role in metastatic nasopharyngeal carcinoma (NPC) remains un...
0
Intraosseous wire fixation versus rigid osseous fixation of mandibular fractures: a preliminary report
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
While wire osteosynthesis has been the accepted modality to use with open reduction of mandibular fractures, several authors have suggested the use of more rigid techniques to achieve the same result while also eliminating adverse effects associated with prolonged maxillomandibular fixation. Few studies have directly c...
1
Ligasure impact() might reduce blood loss, complications, and re-operation occurrence after abdominoplasty in massive-weight-loss patients: A Comparative Study
Panniculectomy & Abdominoplasty CPG
BACKGROUND AND AIMS:: The most effective dissection technique for raising the flap in abdominoplasty is still controversial, particularly in high-risk massive-weight-loss patients. LigaSure Impact() vessel-sealing system (Medtronic, Dublin, Ireland) is an energy device commonly used among different surgical specialties...
0
Distal biceps tendon repair: anchor versus transosseous suture fixation
Distal Radius Fractures
Suture anchor fixation and transosseous suture fixation were compared in 12 fresh-frozen cadaveric radii using either No. 2 braided polyester suture or single Mainstay 3.5-mm threaded anchors (made at the time by Howmedica, Rutherford, NJ) with No. 2 suture. Suture fixation failed at a mean strength of 162 N (range, 12...
0
Bone tumors in a tertiary care hospital of south India: A review 117 cases
MSTS 2018 - Femur Mets and MM
Background: Bone tumors remain a daunting challenge to orthopedic surgeons. The challenge is heightened in developing countries due to limited diagnostic and therapeutic facilities as well as due to ignorance. The published literature on this subject is sparse in our environment. Objective: To determine the pattern of ...
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Electrical stimuli in the central nervous system microenvironment
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Electrical stimulation to manipulate the central nervous system (CNS) has been applied as early as the 1750s to produce visual sensations of light. Deep brain stimulation (DBS), cochlear implants, visual prosthetics, and functional electrical stimulation (FES) are being applied in the clinic to treat a wide array of ne...
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Beta-2 microglobulin in peritoneal dialysis patients: Serum levels and peritoneal clearances
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Beta-2 microglobulin (B2M) is amyloidogenic in long-term hemodialysis patients, with amyloid deposition manifesting as lytic bone lesions, carpal tunnel syndrome, destructive arthropathies, tenosynovitis, and pathologic fractures. To study the behavior of this protein in the peritoneal dialysis population, serum levels...
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The growth kinetics of synovial fibroblastic cells from inflammatory and noninflammatory arthropathies
AMP (Acute Meniscal Pathology)
The growth kinetics of subcultured human synovial fibroblasts from 16 patients with inflammatory and noninflammatory arthropathies were studied in antibiotic free media. The experimental design allowed a clear distinction between the growth rates and final saturation densities achieved. The effects of refeeding and of ...
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Contraindications to the repositioning of fractured or dislocated limbs in the fields
Distal Radius Fractures
Supracondylar fractures of the femor or humerus and fractures of the radius, ulna, tibia or fibula, plus crush injuries of the limbs, most likely should not be manipulated in the field because of the potential for traumatizing adjacent nerves, veins and arteries. An emergency splinting system that allows immobilization...
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Femoral nerve block in a representative sample of elderly people with hip fracture: A randomised controlled trial
Hip Fx in the Elderly 2019
INTRODUCTION: The number of elderly people with hip fracture and dementia is increasing, and many of these patients suffer from pain. Opioids are difficult to adjust and side effects are common, especially with increased age and among patients with dementia. Preoperative femoral nerve block is an alternative pain treat...
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Secondary prevention program for osteoporotic fractures and long-term adherence to bisphosphonates
Management of Hip Fractures in the Elderly
Summary: Our purpose was to assess the impact of a secondary prevention program for osteoporotic fractures in patients with fragility fracture and to determine its effect on long-term compliance with bisphosphonate treatment. Persistence with bisphosphonate use was 71%. Attending follow-up visits was the only variable ...
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Optimal timing of operations to treat fractures of the femoral neck with endoprotheses: CRP as a parameter of postoperative immunologic reaction
Hip Fx Time to Surgery
Background: The optimal time to perform endoprosthesis of hip fractures in the elderly is still under discussion. CRP as an objective marker of postoperative inflammatory reaction should give an indication if early or late surgery is favored. Methods: CRP values from 122 patients with no complications after hip arthrop...
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Prevention and rehabilitation of overuse injuries of the elbow
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
Rehabilitation from injury and prevention of injury are terms that describe differing aspects of the same challenge. The clinician must be continually aware of the principles of rehabilitation and their order of priority (prevent further damage, restore motion, restore strength, reestablish coordination) while supervis...
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Effectiveness of Periarticular Injection After Bipolar Hemiarthroplasty for Displaced Femoral Neck Fracture in Elderly Patients: A Double Blinded Randomized, Controlled Study
Hip Fx in the Elderly 2019
BACKGROUND: Bipolar hemiarthroplasty is a standard treatment for displaced femoral neck fracture in elderly with a normal acetabulum. Several studies have shown controversial results regarding postoperative visual analogue scale, opioid consumption, and the effectiveness of periarticular injection in hip arthroplasty. ...
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Risedronate and ergocalciferol prevent hip fracture in elderly men with Parkinson disease
Management of Hip Fractures in the Elderly
BACKGROUND: There is a high incidence of hip fractures in patients with Parkinson disease (PD). Bone mineral density (BMD) is decreased in patients with PD, correlating with the immobilization-induced bone resorption and hypovitaminosis D with compensatory hyperparathyroidism. OBJECTIVE: To evaluate the effectiveness o...
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Tibial Component Fixation in Total Knee Arthroplasty. A Comparison of Pegged and Stemmed Designs
Management of Hip Fractures in the Elderly
This study compares midterm radiographic, functional, and quality-of-life outcomes in patients receiving a cemented tibial component that has either a short intramedullary stem or one that has a pegged tibial component. A cohort of 181 patients received 225 NexGen cruciate-retaining implants (84 stemmed, 141 pegged) du...
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Big-five personality traits and ego-resilience in amputee soldiers
DoD PRF (Psychosocial RF)
The present study was conducted to see the relationship of personality traits and ego-resilience in soldiers with amputation. The research also took into consideration age, nature of amputation related differences in resilience. Urdu translated versions of scales; Ego Resilience Scale (Block & Kremen, 1996) and NEO-Per...
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Harmonic scalpel versus electrocautery in breast reduction surgery: a randomized controlled trial
Reduction Mammoplasty for Female Breast Hypertrophy
METHODSThirty-one patients were evaluated in a matched-pair design, with random (blinded) assignment of one side to the Harmonic Scalpel, with the other side defaulting to electrocautery. Main outcome measures were: (1) resection/hemostasis time, (2) drainage volume, and (3) postoperative pain. The authors also compare...
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No association between the aluminium content of trabecular bone and bone density, mass or size of the proximal femur in elderly men and women
Management of Hip Fractures in the Elderly
BACKGROUND: Aluminium is considered a bone toxic metal since poisoning can lead to aluminium-induced bone disease in patients with chronic renal failure. Healthy subjects with normal renal function retain 4% of the aluminium consumed. They might thus also accumulate aluminium and eventually be at risk of long-term low-...
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Effect of prostaglandin E1 infusion during and after total hip arthroplasty under hypotensive anesthesia on postoperative liver function and hemorrhage
AAHKS (8) Anesthetic Infiltration
We evaluated the effects of prostaglandin E1 (PGE1) on the liver function and hemorrhage after total hip arthroplasty (THA). Twenty patients with normal liver function were randomly divided into two groups. The patients were anesthetized with spinal anesthesia using 0.5% bupivacaine 4 ml and epidural anesthesia. The la...
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A prospective study comparing mobile-bearing versus fixed-bearing type in total knee arthroplasty using the free-hand-cutting technique
OAK 3 - Non-arthroplasty tx of OAK
The mobile-bearing knee prosthesis was claimed to get more flexion in the laboratory testing and may provide better functional outcome than the conventional fixed-bearing prosthesis in patients. To prove this hypothesis in the patients between those two type prosthesis about flexion and functional out come was our stud...
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Assessment of Low-Grade Meniscal and Cartilage Damage of the Knee at 7 T: A Comparison to 3 T Imaging With Arthroscopic Correlation
OAK 3 - Non-arthroplasty tx of OAK
OBJECTIVES: The aim of this study was to compare the assessment of low-grade meniscal tears and cartilage damage in ultrahigh-field magnetic resonance imaging (MRI) at 7 T to routine clinical MRI at 3 T. MATERIALS AND METHODS: This study was approved by the local ethics committee, and written informed consent was obtai...
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Radiation osteitis and insufficiency fractures after pelvic irradiation for gynecologic malignancies
MSTS 2018 - Femur Mets and MM
Damage to the pelvic bones after radiotherapy for gynecological malignancies is uncommon with megavoltage radiotherapy. It can be misdiagnosed as bony metastases and is a diagnosis of exclusion. We report 12 women, who were treated for endometrial or cervical carcinoma who developed osteitis, femoral head or neck necro...
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Acupuncture for the treatment of chronic knee and back pain
OAK 3 - Non-arthroplasty tx of OAK
Introduction: Because the efficacy of acupuncture was not reliably substantiated by scientific data, the Joint Federal Committee initiated a project comparing the effectiveness of acupuncture to guideline�oriented conventional therapy for chronic pain. Four large, randomized studies were conducted as part of the "Ger...