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1 | Treatment of hypercalcemia of malignancy with intravenous aminohydroxypropylidene bisphosphonate. Results of a stratified, double-blind, randomized two-month dose-response study | MSTS 2018 - Femur Mets and MM | The objective of the study was to evaluate the effects of three different doses of aminohydroxypropylidene bisphosphonate (APD), in the treatment of malignant hypercalcemia. Patients were stratified into two groups according to serum calcium (sCa) after rehydration: group 1 had sCa between 2.75 and 3.25 mmol/L, and gro... |
0 | No Exacerbation of Knee Joint Pain and Effusion Following Preoperative Progressive Resistance Training in Patients Scheduled for Total Knee Arthroplasty: Secondary Analyses From a Randomized Controlled Trial | OAK 3 - Non-arthroplasty tx of OAK | BACKGROUND: Preoperative progressive resistance training (PRT) is controversial in patients scheduled for total knee arthroplasty (TKA), because of the concern that it may exacerbate knee joint pain and effusion.
OBJECTIVE: To examine whether preoperative PRT initiated 5 weeks prior to TKA would exacerbate pain and kne... |
0 | Surgical site infections linked to contaminated surgical instruments | PJI DX Updated Search | Background: This study describes an investigation into a sudden increase in surgical site infection rate following 'clean' surgery. The outbreak involved 15 orthopaedic patients following metal insertion, and five ophthalmology patients who developed endophthalmitis. Aim: An outbreak committee was convened in order to ... |
0 | The patellofemoral joint after total knee arthroplasty without patellar resurfacing | Surgical Management of Osteoarthritis of the Knee CPG | One hundred total knee replacements with a total condylar prosthesis and without patellar resurfacing were followed for a minimum of two years. Eighty-four per cent of the knees were affected by osteoarthrosis. Graded according to the knee-rating system of the Hospital for Special Surgery, there were eighteen excellent... |
0 | Infection after fracture fixation of the tibia: Analysis of healthcare utilization and related costs | DoD LSA (Limb Salvage vs Amputation) | INTRODUCTION: One of the most challenging complications in musculoskeletal trauma surgery is the development of infection after fracture fixation (IAFF). It can delay healing, lead to permanent functional loss, or even amputation of the affected limb. The main goal of this study was to investigate the total healthcare ... |
1 | Titanium alloy pins versus stainless steel pins in external fixation at the wrist: a randomized prospective study | DoD SSI (Surgical Site Infections) | BACKGROUND: Pin-track complications remain the most troublesome disadvantages of external fixation. The purpose of this study was to compare pin-related complications and pain levels after the use of external fixation for the stabilization of distal radial fractures with pins composed of two different materials.
METHOD... |
0 | Body contouring: gynecomastia | Panniculectomy & Abdominoplasty CPG | The male patient's degree of breast sagging is the guideline that this author uses to determine the correct surgical approach to gynecomastia. When the patient has no sagging, a small infraareolar incision suffices. With significant sagging, alternative incisions are usually necessary for skin excision and areolar repo... |
0 | Nabumetone induces less gastrointestinal mucosal changes than diclofenac retard | Management of Hip Fractures in the Elderly | The aim of the study was to compare the efficacy and the effects on the mucosa of the gastrointestinal tract (GIT) of nabumetone and diclofenac retard in patients with osteoarthritis (OA). An open, multicentre, randomised, comparative, endoscopy-blind parallel group study included 201 patients with nabumetone and 193 p... |
0 | All-polyethylene compared with metal-backed tibial components in total knee arthroplasty at ten years: A prospective, randomized controlled trial | PJI DX Updated Search | Background: Several studies have described equivalent performance on radiostereometric analysis at two years for metal-backed compared with all-polyethylene stemmed tibial implants. The purpose of this study was to determine the ten-year survivorship results of these two designs from a large randomized controlled trial... |
0 | The cryosurgical treatment of chondroblastoma of bone: long-term oncologic and functional results | MSTS 2022 - Metastatic Disease of the Humerus | BACKGROUND: Chondroblastoma of bone is a rare tumor that occurs most often in the epiphysis or apophysis of long bones. This benign tumor sometimes shows aggressive or malignant behaviour, and rarely metastases occur. Since wide resection often leads to growth impairment, intra-lesional curettage followed by an adjuvan... |
0 | Radial Interventions: Present and Future Indications | DOD - Acute Comp Syndrome CPG | Since its first introduction, radial access for diagnostic and interventional cardiovascular procedures has progressively evolved with advances in understanding, capabilities, and ease of operation. Numerous studies have demonstrated its safety, efficacy, and cost-effectiveness. Overall, radial catheterization is a val... |
0 | Discoid lateral meniscus in children. Long-term follow-up after total meniscectomy | Diagnosis and Treatment of Osteochondritis Dissecans AUC | We retrospectively reviewed the long-term results of total meniscectomy performed in seventeen knees (fourteen children) to treat a discoid lateral meniscus. The mean duration of follow-up was 19.8 years (range, 12.5 to 26.0 years). On the basis of the rating system of the International Knee Documentation Committee, se... |
0 | Biologic Options for Articular Cartilage Wear (Platelet-Rich Plasma, Stem Cells, Bone Marrow Aspirate Concentrate) | OAK 3 - Non-arthroplasty tx of OAK | Biological treatments for articular cartilage repair have gained in popularity in the past decade. Advantages of these therapies include minimal invasiveness, improved healing time, and faster recovery. Biological therapies for cartilage repair include platelet-rich plasma, bone marrow aspirate concentrate, and cell-ba... |
0 | Risk of postmenopausal hip fracture in Mexican American women | Management of Hip Fractures in the Elderly | To assess the risk of hip fracture in Mexican Americans, the ethnicity of 80 women aged 50 years and over admitted with hip fractures to a Texas hospital was compared with that of age-matched women hospitalized for other reasons. The risk of fracture for Mexican Americans was only 35 per cent that of Whites (95% CI = 1... |
0 | Optimal recording electrode placement in the lumbrical-interossei comparison study | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | The lumbrical-interossei comparison study is commonly employed in the electrodiagnosis of carpal tunnel syndrome. Placement of the recording electrodes relies on anatomic landmarks as the muscles being recorded cannot be seen or palpated. To determine the optimal active electrode location, 15 controls and 5 patients we... |
0 | Factors Associated With Bone Density Monitoring While on Antiosteoporosis Treatment in Routine Clinical Practice: A Registry-Based Cohort Study | Hip Fx in the Elderly 2019 | The role for bone mineral density (BMD) monitoring while on antiosteoporosis therapy remains controversial. The current study used population-based registries to identify factors associated with BMD monitoring in women within 5 yr of receiving antiosteoporosis treatment vs treatment without monitoring in routine clinic... |
0 | Morphological and Functional Hip Long-Term Results after Exstrophy Repair | Developmental Dysplasia of the Hip 2020 Review | Introductionâ??Abnormalities of the bony pelvis in exstrophy-epispadias complex (EEC) and their possible relation to hip disease are well described. However, there is a lack of information about long-term orthopedic consequences and hip function in patients with EEC. Therefore, we investigated clinical and radiological... |
1 | Effect of tibial tunnel position on arthroscopically assisted anterior cruciate ligament reconstruction using bone-patellar tendon-bone grafts: a prospective study | Anterior Cruciate Ligament Injuries CPG | INTRODUCTION: The aim of this research was to study the effect of the tibial tunnel position in anterior cruciate ligament (ACL) reconstruction using bone-patellar tendon-bone (BPTB) grafts in ensuring optimal knee functioning. METHODS: A prospective study was conducted on 41 patients who underwent arthroscopically ass... |
1 | Does the location of placement of meniscal sutures have a clinical effect in the all-inside repair of meniscocapsular tears? | AMP (Acute Meniscal Pathology) | BACKGROUND: Meniscocapsular separation (MCS) is a lesion of the area which is attached from the peripheral section of the meniscus to the capsule and is seen less often than other meniscus injuries. The aim of this study was to investigate which of the different side applications of all-inside MCS repair of the meniscu... |
0 | Revisions of monoblock metal-on-metal THAs have high early complication rates | PJI DX Updated Search | BACKGROUND: A relatively high percentage of monoblock metal-on-metal total hip arthroplasties (THAs) undergo early revision. Revision of these THAs poses challenges unique to this implant type. The early complications after these revisions remain unreported as do the clinical and demographic factors associated with the... |
0 | Multiple territory watershed infarcts following spinal anaesthesia | Surgical Management of Osteoarthritis of the Knee CPG | Hypotension is one of the most common complications of spinal anaesthesia (SA). The intraoperative drop in the blood pressure is clearly associated with increased morbidity and mortality. In order to increase the awareness of this complication, we report a case of devastating stroke following an SA in a previously well... |
1 | In with the new, out with the old? Comparison of two approaches for psoas compartment block | AAHKS (9/10) Regional Nerve Blocks | We compared the approaches of Winnie and Capdevila for psoas compartment block (PCB) performed by a single operator in terms of contralateral spread, lumbar plexus blockade, and postoperative analgesic efficacy. Sixty patients underwent PCB (0.4 mL/kg levobupivacaine 0.5%) and subsequent spinal anesthesia for primary j... |
0 | Liposuction and tumescent surgery | Panniculectomy & Abdominoplasty CPG | When guidelines for tumescent surgery are followed, treatment of patients with a broad range of concerns can be extremely effective. Whether its use is as a primary technique as in liposuction, or as an adjunct to another procedure such as reduction mammoplasty, the effects of reduced blood loss, pain control, and flui... |
0 | Effect of atorvastatin on 5-fluorouracil-induced experimental oral mucositis | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | PURPOSE: Oral mucositis (OM) is a frequent side effect in patients with cancer. We investigate the effect of atorvastatin (ATV), a cholesterol-lowering drug, on OM induced by 5-fluorouracil (5-FU) in hamsters. METHODS: OM was induced by the i.p. administration of 5-FU, with excoriations of the cheek pouch mucosa. The a... |
0 | Sarcopenia is a prognostic factor for TKIs in metastatic thyroid carcinomas | MSTS 2022 - Metastatic Disease of the Humerus | Purpose: Among patients with various cancers receiving anticancer drugs, sarcopenia is associated with poor survival and treatment outcomes. We conducted an observational study using skeletal muscle index (SMI) evaluation to investigate the association between sarcopenia and treatment outcomes of tyrosine kinase inhibi... |
0 | Common complications of advanced cancer | MSTS 2022 - Metastatic Disease of the Humerus | Complications due to cancer and its treatment are common and increase in incidence and severity as the disease progresses. Central nervous system complications affect 15% to 20% of patients, and up to 75% have bone metastases at some point during the disease process. Endocrine abnormalities include hypercalcemia, adren... |
0 | Pathologic fractures in patients with multiple myeloma undergoing bisphosphonate therapy: incidence and correlation with course of disease | MSTS 2018 - Femur Mets and MM | OBJECTIVE: The purposes of this study were single-center analysis of the incidence of pathologic fractures in patients with multiple myeloma undergoing bisphosphonate therapy and correlation of the occurrence of pathologic fractures with the course of disease.
MATERIALS AND METHODS: One hundred ninety-one patients with... |
0 | Common Tendon and Muscle Injuries: Upper Extremities | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Ultrasonography is a useful diagnostic tool for the assessment of various soft tissue disorders. This article reviews a number of common muscle and tendon injuries affecting the upper extremity, discussing and illustrating their ultrasound imaging appearance. Important regional anatomy and imaging techniques and tips a... |
1 | Transcutaneous electrical nerve stimulation for postoperative pain relief after arthroscopic rotator cuff repair: a prospective double-blinded randomized trial | Trial Systematic Review Project | BACKGROUND: Arthroscopic rotator cuff repair (ARCR) can be associated with significant postoperative pain. Concern for opioid abuse has led surgeons to identify alternative, efficacious methods of postoperative analgesia. To determine whether transcutaneous electrical nerve stimulation (TENS) can have a similarly benef... |
1 | Concomitant arthroscopic SLAP and rotator cuff repair | Optimizing the Management of Full-Thickness Rotator Cuff Tears | BACKGROUND: The outcomes of combined arthroscopic repairs of a SLAP (superior labral anterior-posterior) lesion and a rotator cuff tear are not known. We compared the outcomes in a cohort of patients who had undergone concomitant arthroscopic repairs of a SLAP lesion and a rotator cuff tear with those in a cohort of pa... |
0 | Pediatric fluid resuscitation after thermal injury | DoD - ACS - Interrater Reliability | Fluid resuscitation after thermal injury in a child or infant can pose a set of unique and significant challenges. Many approaches to fluid resuscitation of children after burns exist, and most are nonevidence based. This review will highlight the important concepts involved in pediatric fluid resuscitation from therma... |
0 | Comparison of three modes of aerobic exercise combined with resistance training on the pain and function of patients with knee osteoarthritis: A randomized controlled trial | OAK 3 - Non-arthroplasty tx of OAK | OBJECTIVES: To investigate the effects of three modes of aerobic exercise (lower limbs with and without weight bearing and upper limb) for knee osteoarthritis.
DESIGN: Randomized controlled trial.
SETTING: Sports medicine clinic.
PARTICIPANTS: Seventy-eight patients with knee osteoarthritis were divided into 3 groups o... |
1 | Alignment and orientation of the components in total knee replacement with and without navigation support | Surgical Management of Osteoarthritis of the Knee CPG | Bilateral sequential total knee replacement was carried out under one anaesthetic in 100 patients. One knee was replaced using a CT-free computer-assisted navigation system and the other conventionally without navigation. The two methods were compared for accuracy of orientation and alignment of the components. There w... |
0 | Mammaplasty with reduced blood loss: Effect of noradrenalin | Reduction Mammoplasty for Female Breast Hypertrophy | Bilateral reduction mammaplasties were used to study the effect of noradrenalin I/800,000 as an aid to reduce bleeding during surgical operations. One breast was infiltrated with noradrenalin while the opposite breast was infiltrated with the same amount of saline to act as a control. Bleeding was reduced to less than ... |
0 | Clinical results of the one-bone forearm | Distal Radius Fractures | Between 1973 and 1991, 19 patients underwent creation of a one-bone forearm at our institution as treatment for radioulnar instability secondary to trauma ("type 1" patients) or tumor resection or congenital deformity ("type 2" patients). Seventeen had failed previous reconstruction attempts. Ten one-bone forearms were... |
0 | Graft-enhanced arthrodesis | DoD LSA (Limb Salvage vs Amputation) | This article reviews the various sites in the foot and ankle where the use of a bone graft to enhance arthrodesis may be indicated. Specific indications are reviewed in detail and demonstrated with clinical examples. Bone graft classification is discussed along with a comparison of autografts and allografts. The contro... |
0 | Evaluation of periodontal space widening in patients with antiresorptive drug-related osteonecrosis of the Jaws (ARONJ) on panoramic radiographs | MSTS 2018 - Femur Mets and MM | Background/Aim: The purpose of this study was to evaluate a potential widening of the periodontal space as an initial measurable imaging criterium on panoramic radiographs in patients with the diagnosis of antiresorptive drug related osteonecrosis of the jaw (ARONJ). Patients and Methods: A retrospective analysis of pa... |
0 | The efficacy of Arthrotec in the treatment of osteoarthritis | OAK 3 - Non-arthroplasty tx of OAK | In a doubleâ?blind study, 455 patients with osteoarthritis were randomly assigned to receive a combination of Arthrotec, 50 mg of diclofenac and 200 micrograms of misoprostol, or 50 mg of diclofenac; the drugs were given two or three times daily for 4 weeks. At weeks 2 and 4 of treatment, no significant differences be... |
0 | Arthroscopic meniscal repair with fibrin clot of complete radial tears of the lateral meniscus in the avascular zone | AMP (Acute Meniscal Pathology) | Peripheral lateral meniscal tears are amenable to arthroscopic meniscal repair. However, the posterolateral aspect of the lateral meniscus adjacent to the popliteus tendon is devoid of penetrating peripheral vessels and therefore difficult to heal. A complete radial split at this site is usually treated with total meni... |
0 | Ultralow-dose micronized 17beta-estradiol and bone density and bone metabolism in older women: a randomized controlled trial | Management of Hip Fractures in the Elderly | CONTEXT: Estrogen therapy is known to prevent osteoporosis, but studies have shown that conventional doses increase adverse events. Whether lower doses, one quarter of standard treatment, prevent bone loss is not known. OBJECTIVE: To examine the effect of 3 years of treatment with 0.25 mg/d of micronized 17beta-estradi... |
0 | The Italian society for rheumatology clinical practice guidelines for the diagnosis and management of knee, hip and hand osteoarthritis | OAK 3 - Non-arthroplasty tx of OAK | Osteoarthritis (OA) is the most common musculoskeletal disease leading to functional decline and loss in quality of life. Knees, hands and hips are frequently affected joints with a relevant clinical and socio-economic burden. An evidence-based approach to OA management is essential in order to improve patientsâ?? heal... |
0 | Does intraarticular steroid infiltration increase the rate of infection in subsequent total knee replacements? | AAHKS (2) Corticosteroids | Steroid injection into the arthritic joint is a well-known treatment. Its efficacy is well documented. An increase in the incidence of infection secondary to steroid injection has been reported in recent literature. Based on the current literature we carried out a retrospective study to evaluate the incidence of infect... |
1 | Association of timing of surgery for hip fracture and patient outcomes | Management of Hip Fractures in the Elderly | CONTEXT: Previous studies of surgical timing in patients with hip fracture have yielded conflicting findings on mortality and have not focused on functional outcomes. OBJECTIVE: To examine the association of timing of surgical repair of hip fracture with function and other outcomes. DESIGN: Prospective cohort study inc... |
0 | Post-operative delirium: predictors and prognosis in elderly orthopedic patients | AAHKS (8) Anesthetic Infiltration | OBJECTIVE: To compare the effect of post-operative analgesia using epidural versus intravenous infusions on the incidence of delirium after bilateral knee replacement surgery in elderly patients. Additional risk factors and impact on post-operative recovery were also assessed.
DESIGN: Prospective randomized controlled ... |
0 | Analgesic Effects of Diluted Bee Venom Acupuncture Mediated by δ-Opioid and α2-Adrenergic Receptors in Osteoarthritic Rats | OAK 3 - Non-arthroplasty tx of OAK | Context � Pain from osteoarthritis is associated with peripheral nociception and central pain processing. Given the unmet need for innovative, effective, and well-tolerated therapies, many patients, after looking for more satisfactory alternatives, decide to use complementary and alternative modalities. The analgesic... |
0 | Correlation of Knee and Hindfoot Deformities in Advanced Knee OA: Compensatory Hindfoot Alignment and Where It Occurs | Surgical Management of Osteoarthritis of the Knee CPG | BACKGROUND: Many patients undergoing TKA have both knee and ankle pathology, and it seems likely that some compensatory changes occur at each joint in response to deformity at the other. However, it is not fully understood how the foot and ankle compensate for a given varus or valgus deformity of the knee. QUESTIONS/PU... |
1 | Efficacy and Safety of Intra-Articular Platelet-Rich Plasma in Osteoarthritis Knee: A Systematic Review and Meta-Analysis | PRP (Platelet-Rich Plasma) | Background: Knee osteoarthritis (KOA) is a common disease in aged adults. Intra-articular (IA) injection of platelet-rich plasma (PRP) therapy is an effective minimally invasive treatment for KOA. We aimed to compare the efficacy and safety of platelet-rich plasma (PRP) with placebo or other conservative treatments.
Me... |
1 | The use of tissue adhesive for skin closure in body contouring surgery | Panniculectomy & Abdominoplasty CPG | BACKGROUND: Abdominoplasty and mammoplasty are cosmetic surgeries that demand relatively more time for skin closure. METHODS: Skin closure with 4.0 Mononylon (Ethicon, Summerville, NJ, USA) continuous subcuticular suture and with Dermabond (Ethicon, USA) (octylcyanoacrylate) was compared among 37 patients who had under... |
1 | Noninvasive laser neurolysis in carpal tunnel syndrome | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | The peripheral nervous system is photosensitive providing the scientific rationale for this study, which determines the efficacy and safety of laser light exposure in 30 cases with CTS. Nine joules of energy over five points (7-15 treatments) reversed CTS in 77% of cases with three-fold normalization of CMAP. A photobi... |
0 | Concurrent proximal fractures are rare in distal forearm fractures: A National Cross-sectional Study | Pediatric Supracondylar Humerus Fracture 2020 Review | Introduction: Distal forearm fractures (DFF) account for 1.5% of emergency department (ED) visits in the United States. Clinicians frequently obtain imaging above/below the location of injury to rule out additional injuries. We sought to determine the incidence of associated proximal fractures (APF) in the setting of D... |
0 | Carpal tunnel syndrome secondary to intratendinous infiltration by tophaceous gout | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Carpal tunnel syndrome caused by gout is rare. We describe a case of entrapment of the median nerve secondary to intratendinous infiltration by gouty tophi in a 54-year-old man. The tophus was excised from the profundus tendon but the superficialis was too infiltrated and destroyed to be saved. The patient made an unev... |
0 | Long-term results of vascularized bone graft for stage III Kienbock disease | Distal Radius Fractures | PURPOSE: Vascularized bone grafting (VBG) is one of the therapeutic approaches for treating advanced Kienbock disease; however, few reports on long-term outcomes are available for this technique. The purpose of this study is to evaluate long-term results by following up patients with stage III Kienbock disease for more... |
0 | Emotion regulation difficulties as a prospective predictor of posttraumatic stress symptoms following a mass shooting | DoD PRF (Psychosocial RF) | A strong positive association between emotion regulation difficulties (ERD) and posttraumatic stress symptoms (PTSS) has been consistently evidenced in cross-sectional research. However, a lack of prospective research has limited hypotheses regarding the temporal relationship between trauma exposure, ERD, and PTSS. The... |
1 | Comparing the effects of individualized, standard, sham and no acupuncture in the treatment of knee osteoarthritis: a multicenter randomized controlled trial | OAK 3 - Non-arthroplasty tx of OAK | BACKGROUND: Acupuncture is an effective yet complex therapy, integrating syndrome differentiation, selection of appropriate acupoints and skillful needling techniques. Clinicians carefully tailor acupuncture treatment to each patient. However, most clinical trials of acupuncture have been based on a standardized formul... |
0 | Results of 20 consecutive patients treated with the Repiphysis expandable prosthesis for primary malignant bone | Pediatric Supracondylar Humerus Fracture 2020 Review | Limb-salvage for primary malignant bone tumors in pediatric patients presents a unique challenge when resection includes an active physis. Early expandable prostheses required open surgical procedures to achieve lengthening. Newer prostheses are capable of achieving expansion without open procedures through the use of ... |
0 | A dual-color fluorescence imaging-based system for the dissection of antiangiogenic and chemotherapeutic activity of molecules | Reconstruction After Skin Cancer | We have developed a simple yet sensitive dual color fluorescence-based technique for dissecting the tumor-neovascularization relationship and evaluated the susceptibility of each component to therapeutic interventions. Green fluorescent protein (GFP)-expressing melanoma cells were cocultured with endothelial cells on d... |
0 | Effects of education and strength training on functional tests among older people with osteoarthritis | OAK 3 - Non-arthroplasty tx of OAK | BACKGROUND: Hip and knee osteoarthritis are important causes of pain and disability among older people. Education and strength training can alleviate symptoms and avoid functional deterioration. AIM: To assess muscle strength, fall risk and quality of life of older people with osteoarthritis and the effects of physioth... |
0 | Provided support, caregiver burden and well-being in partners of persons with spinal cord injury 5 years after discharge from first inpatient rehabilitation | DoD PRF (Psychosocial RF) | STUDY DESIGN: Cross-sectional study.
OBJECTIVES: To describe type and regularity of support given by partners for individuals with paraplegia versus tetraplegia 5 years after discharge from first inpatient rehabilitation; to describe perceived caregiver burden, mental health and life satisfaction among partners; and to... |
0 | Radiological evaluation of cartilage after microfracture treatment: a long-term follow-up study | Surgical Management of Osteoarthritis of the Knee CPG | INTRODUCTION: Recent literature revealed good short-term results after microfracturing (MFX) of isolated focal cartilage defects in the knee joint. Study purpose was a long-term evaluation of patients who received MFX through a multimodal approach, correlating clinical scores and morphological pre- and postoperative MR... |
1 | Infection safety of dexamethasone in total hip and total knee arthroplasty: a study of eighteen thousand, eight hundred and seventy two operations | AAHKS (2) Corticosteroids | PURPOSE: Dexamethasone has been shown to prevent post-operative nausea and vomiting (PONV) and seems to reduce post-operative pain. Both factors, which can extend the hospital stay, delay rehabilitation, and impact patient satisfaction. Because of the immunosuppressive and glucose-rising effects of dexamethasone, there... |
0 | The influence of sexual orientation and sexual role on male groomingâ?쳌related injuries and infections | DoD PRF (Psychosocial RF) | Aim: Pubic hair grooming is a common practice in the United States and coincides with prevalence of groomingâ?related injuries. Men who have sex with men (MSM) groom more frequently than men who have sex with women (MSW). We aim to characterize the influence of sexual orientation and sexual role on grooming behavior, ... |
0 | Fractures of the clavicle in the adult. Epidemiology and classification | DoD SSI (Surgical Site Infections) | From 1988 to 1994 a consecutive series of 1000 fractures of the adult clavicle was treated in the Orthopaedic Trauma Clinic of the Royal Infirmary of Edinburgh. In males, the annual incidence was highest under 20 years of age, decreasing in each subsequent cohort until the seventh decade. In females, the incidence was ... |
0 | Increased sensitivity of rheumatoid synoviocytes to Schnurri-3 expression in TNF-alpha and IL-17A induced osteoblastic differentiation | TO: WNT2 Pathway Modulator | OBJECTIVE: To compare the effects of TNF-alpha and IL-17A on osteogenic differentiation of isolated fibroblast-like synoviocytes (FLS) from healthy donors, osteoarthritis (OA) and rheumatoid arthritis (RA) patients.
METHODS: FLS were cultured in osteogenic medium, with and without TNF-alpha and/or IL-17A. Extracellular... |
0 | Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for Clinical and Research Applications: recommendations of the International RDC/TMD Consortium Network* and Orofacial Pain Special Interest Groupâ? | DoD PRF (Psychosocial RF) | The original Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) Axis I diagnostic algorithms have been demonstrated to be reliable. However, the Validation Project determined that the RDC/TMD Axis I validity was below the target sensitivity of â?¥ 0.70 and specificity of â?¥ 0.95. Consequently, thes... |
0 | Impaction grafting of the acetabulum with ceramic bone graft substitute mixed with femoral head allograft: High survivorship in 43 patients with a median follow-up of 7 years | PJI DX Updated Search | Background and purpose Restoration of bone stock at revision hip surgery remains a challenge. Alternative graft materials with suitable mechanical properties for impaction grafting have been sought due to issues with infection, antigenicity, cost, and availability of allograft. We have previously presented good short-t... |
0 | Provider volumes and early outcomes of primary total joint replacement in Ontario | Surgical Management of Osteoarthritis of the Knee CPG | BACKGROUND: A relation between provider volume and outcome of total joint replacement (TJR) has not been demonstrated in Canada. Given the recent increase in TJR, changing patient characteristics and small sizes of previous Ontario studies, we reassessed whether adverse outcomes of TJR are related to hospital and surge... |
0 | The use of continuous passive motion following knee cartilage defect surgery: a systematic review | Diagnosis and Treatment of Osteochondritis Dissecans AUC | We evaluated the clinical evidence of using continuous passive motion postoperatively after treating articular cartilage lesions of the knee. We hypothesized that postoperatively, the use of continuous passive motion improves the outcomes of cartilage restoration procedures. Multiple medical databases (MEDLINE, EMBASE,... |
0 | Osteoarthritis year 2011 in review: imaging in OA--a radiologists' perspective | OAK 3 - Non-arthroplasty tx of OAK | With major technological advances and application of magnetic resonance imaging (MRI) to large longitudinal osteoarthritis (OA) studies the role of imaging has become increasingly important for OA research over the last years. Currently, radiography, MRI and ultrasound are the most established imaging tools applied in ... |
0 | Fracture risk reduction during treatment with teriparatide is independent of pretreatment bone turnover | Management of Hip Fractures in the Elderly | INTRODUCTION: Teriparatide is a bone formation agent that increases bone turnover and mass, resulting in an increase in bone strength and a decrease in fracture risk. METHODS: The primary purpose of this analysis was to evaluate the association between pretreatment bone turnover marker (BTM) concentrations and the abso... |
0 | Outcomes of hip arthroplasty in patients younger than 28 years old | PJI DX Updated Search | BACKGROUND: Osteoarthritis is a serious social problem. Young people usually present with secondary degenerative changes. These patients find it particularly difficult to accept symptoms, as they are at their peak of professional activity and family life. They have high expectations regarding improvement in life comfor... |
0 | Influence of a total joint infection control bundle on surgical site infection rates | PJI DX Updated Search | Quality improvement initiatives combined with pulsed xenon ultraviolet room disinfection were implemented to reduce surgical site infections (SSIs) in patients undergoing total joint procedures. After 12 months, knee SSIs were reduced from 4 to 0 (P = .03) and hip SSIs were reduced from 3 to 0 (P = .15) for a combined ... |
0 | Exercise-induced shin pain | DOD - Acute Comp Syndrome CPG | Exercise-induced shin pain encompasses a wide range of patient complaints. Shin splints is a nondescriptive term that does not convey an accurate diagnosis. With a thorough history and exam, the clinical diagnosis is normally apparent and can be confirmed with radiological studies. © 2005 Human Kinetics. |
1 | Comparing different preparations and doses of rosehip powder in patients with osteoarthritis of the knee: An exploratory randomized active-controlled trial | OAK 3 - Non-arthroplasty tx of OAK | Aim: We compared original rosehip powder consisting of whole rosehips including seeds, with two different doses of a novel enhanced rosehip powder of rosehips without their seeds, for patients with knee osteoarthritis (OA). Methods: A total of 150 patients with symptomatic knee OA were randomly assigned to original pow... |
0 | Radiographic joint space narrowing in osteoarthritis of the knee: relationship to meniscal tears and duration of pain | AMP (Acute Meniscal Pathology) | OBJECTIVE: The objective of this study was to assess, with knee radiography, joint space narrowing (JSN) and its relationship to meniscal tears, anterior cruciate ligament (ACL) ruptures, articular cartilage erosion, and duration of pain in patients with knee osteoarthritis.
MATERIALS AND METHODS: A total of 140 patien... |
0 | Characterization of viscosupplementation formulations using chemical exchange saturation transfer (ViscoCEST) | OAK 3 - Non-arthroplasty tx of OAK | BACKGROUND: Osteoarthritis (OA) is characterized by progressive loss of cartilage in joints, and is a major cause of pain and disability, and imposes significant health care expense. New therapies are being developed to treat the symptomatic effect of OA, one of which is intra-articular injection of viscosupplementatio... |
0 | Prognosis of Bell Palsy: A Clinical, Neurophysiological, and Ultrasound Study | Pediatric Supracondylar Humerus Fracture 2020 Review | PURPOSE: Bell palsy is the most common cause of acute facial nerve paralysis. Ultrasound has proved its ability in detecting structural lesions along the course of the affected nerves.The current work aimed at studying the accuracy of ultrasound to predict the prognosis of Bell palsy in correlation to the clinical scal... |
0 | Long-term open-label study of tanezumab for moderate to severe osteoarthritic knee pain | OAK 3 - Non-arthroplasty tx of OAK | OBJECTIVE: This study was designed to evaluate the longâ?term safety and effectiveness of repeated doses of the humanized antiâ?nerve growth factor antibody, tanezumab, during openâ?label treatment of patients with OA knee pain. DESIGN: The current study (clinicaltrials.gov identifier: NCT00399490) was a multicenter... |
0 | Influence of wound drainage in primary total knee arthroplasty without tourniquet | PJI DX Updated Search | PURPOSE: Although it remains the golden standard, several authors have questioned the role of pneumatic tourniquets in primary knee arthroplasty in recent studies. An intra-articular wound drainage is widely used in the field of total knee arthroplasty although the benefit of postoperative wound drainage is controversi... |
0 | HPV Lesions and Other Issues in the Oral Cavity Treatment and Removal without Pain | Dental Implant Infection | Due to different oral and dental conditions, oral mucosa lesions such as those caused by the human papilloma virus and temporomandibular joint pathologies often have to be treated by surgical, ablative or extractive procedures. The treatment and control of pain and inflammation during these procedures is essential to g... |
0 | Efficacy and Cost-Benefit Analysis of a Global Environmental Cleaning Algorithm on Hospital-Acquired Infection Rates | PJI DX Updated Search | OBJECTIVE: This study evaluates clinical outcomes and cost-benefit analysis before and after implementation of a global environmental cleaning algorithm on all hospital-acquired infection (HAI) rates. METHODS: A retrospective, quasi-experimental study design was used to review the hospital's procedure and infection rat... |
1 | Ultrasound screening for developmental dysplasia of the hip in the neonate: the effect on treatment rate and prevalence of late cases | Developmental Dysplasia of the Hip CPG | OBJECTIVE: To assess the effect of ultrasound screening on primary diagnosis, management, and prevalence of late cases of developmental dysplasia of the hip (DDH). DESIGN: A randomized, controlled trial, including 11,925 newborn infants who were allocated to receive either general, or selective or no ultrasound screeni... |
1 | Ultrasonography in screening for developmental dysplasia of the hip in newborns: systematic review | Developmental Dysplasia of the Hip CPG | OBJECTIVE: To assess the accuracy and effectiveness of the screening of all newborn infants for developmental dysplasia of the hip (DDH) using ultrasound imaging, as is standard practice in some European countries but not in the United Kingdom, the United States, or Scandinavia. DESIGN: Systematic review. DATA SOURCES:... |
1 | Timing of antimicrobial prophylaxis and the risk of surgical site infections: Results from the trial to reduce antimicrobial prophylaxis errors | PJI DX Updated Search | OBJECTIVE: The objective of this study is to determine the optimal timing for surgical antimicrobial prophylaxis (AMP). SUMMARY BACKGROUND DATA: National AMP guidelines should be supported by evidence from large contemporary data sets. METHODS: Twenty-nine hospitals prospectively obtained information on AMP from 4472 r... |
0 | A cost-utility analysis of open and endoscopic carpal tunnel release | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | BACKGROUND: Open carpal tunnel release (OCTR) is the standard procedure for the surgical treatment of carpal tunnel syndrome. With the advent of minimally invasive surgery, endoscopic carpal tunnel release (ECTR) was introduced. OBJECTIVE: To use a decision analytical model to compare ECTR with OCTR in an economic eval... |
0 | Comparison of intra-articular simple compression and extra-articular distal radial fractures | Distal Radius Fractures | BACKGROUND: The impact of a single well-reduced or stable intra-articular fracture oriented in the sagittal plane on the outcome of internal fixation of a distal radial fracture is uncertain. We tested the hypothesis that wrist motion and function scores would not differ between patients with an extra-articular fractur... |
0 | CNS disorders presenting as a general surgical problem | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | In this article a number of neurosurgical problems which can mimic different conditions and therefore can present to the general surgeon and others are discussed. It is wise to consider neurological pathology amongst the differential diagnoses, especially when the more common alternatives have been excluded. (copyright... |
0 | Incidence of hip fracture in Oslo, Norway: differences within the city | Management of Hip Fractures in the Elderly | Oslo, Norway has the highest incidence of hip fractures ever reported. There are great differences in life expectancy between city regions in Oslo, and we investigated if there were any differences in incidence of hip fracture within the city. In 1989, all new fractures of the proximal femur in Oslo residents 50 years ... |
0 | Clinical Questions and Answers on Gastrointestinal Endoscopy during the Novel COVID-19 Pandemic | Coronavirus Disease 2019 (COVID-19) | Some situations may require endoscopy during the COVID-19 (Coronavirus Disease 2019) pandemic. Here, we describe the necessary precautions in the form of clinical questions and answers (Q&A) regarding the safe deployment of gastrointestinal endoscopy in such situations while protecting endoscopy staff and patients from... |
0 | Osteolytic cortical destruction: an unusual pattern of skeletal metastases | MSTS 2018 - Femur Mets and MM | Twenty-two histologically proven cortical metastases in 11 patients with bronchogenic carcinoma (10 squamous cell and one adenocarcinoma) were studied. The intracortical foci could be classified according to four distinctive patterns of bone destruction: small focal intracortical lesions ("cookie-bite" or "cookie-cutte... |
1 | Imaging of the Knee Following Repair of Focal Articular Cartilage Lesions | Osteochondritis Dissecans 2020 Review | Focal chondral or osteochondral lesions of the knee are common lesions involving either the cartilage layers or the cartilage layers and the subchondral bone. Despite their heterogeneous clinical presentation, they are important risk factors for the premature development of osteoarthritis. Therefore, early detection of... |
1 | Forklift related injuries | DoD LSA (Limb Salvage vs Amputation) | Orthopaedic injuries caused by forklift vehicles are becoming more common. Following a series of forklift related admissions to our institution, we were prompted to study a consecutive group of 48 patients in detail with respect to mechanism of injury, pattern of injury sustained, complications and final outcome. Most ... |
0 | Cathepsin D: newly discovered functions of a long-standing aspartic protease in cancer and apoptosis | MSTS 2018 - Femur Mets and MM | The lysosomal aspartic protease cathepsin D (cath-D) is over-expressed and hyper-secreted by epithelial breast cancer cells. This protease is an independent marker of poor prognosis in breast cancer being correlated with the incidence of clinical metastasis. Cath-D over-expression stimulates tumorigenicity and metastas... |
1 | Curative effect of artificial femoral head replacement and its effect on hip joint function and complications of senile patients with femoral intertrochanteric fracture | Hip Fx in the Elderly 2019 | Curative effect of artificial femoral head replacement on hip joint function and complications of elderly patients with femoral intertrochanteric fracture were investigated. Eighty patients who were operated for femoral intertrochanteric fractures operation were randomly divided into observation group (n=40) and contro... |
0 | Prevalence and predictors of open-angle glaucoma: results from the visual impairment project | Upper Eyelid and Brow Surgery | PURPOSE: To determine the prevalence and investigate predictors of open-angle glaucoma in Victoria, Australia. DESIGN: Two-site, population-based cross-sectional study. PARTICIPANTS: Permanent residents aged 40 years and older at recruitment from 1992 through 1996. METHODS: A cluster-stratified random sample of 4744 pa... |
0 | Is Sport Activity Possible After Arthroscopic Meniscal Allograft Transplantation? Midterm Results in Active Patients | OAK 3 - Non-arthroplasty tx of OAK | BACKGROUND: Meniscal allograft transplantation (MAT) has produced good to excellent results in the general population; however, few investigations have examined MAT in athletes and sport-related outcomes.
PURPOSE: To report midterm clinical outcomes of MAT and the rate of return to sport in a physically active populati... |
0 | Denosumab reduces early migration in total knee replacement | OAK 3 - Non-arthroplasty tx of OAK | Background and purpose - Aseptic loosening is a main cause of late revision in total knee replacement (TKR). Migration of implants as measured by radiostereometric analysis (RSA) can predict future loosening. This migration is associated with bone resorption. Denosumab is a human monoclonal antibody that binds to recep... |
1 | Intra-articular bupivacaine reduces postoperative pain and meperidine use after total hip arthroplasty: a randomized, double-blind study | AAHKS (8) Anesthetic Infiltration | One hundred patients receiving unilateral total hip arthroplasty (THA) were randomized to receive an intra-articular injection of 300mg bupivacaine or normal saline after completion of surgery. Pain scores of the bupivacaine group were significantly lower than those of the control group the first 12hours postoperativel... |
0 | Radiographic Determinants of Early Failure After Posterior Wall Acetabular Fracture Fixation | Hip Fx in the Elderly 2019 | A retrospective review was conducted at an academic trauma center to determine whether fracture characteristics or aspects of native anatomy are predictive of early failure after fixation of posterior wall acetabular fractures. A chart review of posterior wall acetabular fractures treated from 2004 to 2009 yielded the ... |
0 | On Parallel Streams through the Mouse Dorsal Lateral Geniculate Nucleus | Upper Eyelid and Brow Surgery | The mouse visual system is an emerging model for the study of cortical and thalamic circuit function. To maximize the usefulness of this model system, it is important to analyze the similarities and differences between the organization of all levels of the murid visual system with other, better studied systems (e.g., n... |
0 | A trial assessing N-3 as treatment for injury-induced cachexia (ATLANTIC trial): does a moderate dose fish oil intervention improve outcomes in older adults recovering from hip fracture? | Management of Hip Fractures in the Elderly | BACKGROUND: Proximal femoral fractures are associated with increased morbidity and mortality. Pre-existing malnutrition and weight loss amongst this patient group is of primary concern, with conventional nutrition support being largely ineffective. The inflammatory response post proximal femoral fracture surgery and th... |
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