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Matrix metalloproteinase-2 as a target for head and neck cancer therapy
MSTS 2018 - Femur Mets and MM
Introduction: Matrix metalloproteinase (MMP)-2 is a zinc-dependent proteinase that is capable of cleaving all extracellular matrix (ECM) substrates. Degradation of the matrix is a key event in the progression, invasion, and metastasis of potentially malignant and malignant lesions of the head and neck. Therefore, block...
0
Barriers to Participant Retention in Knee Osteoarthritis Clinical Trials: A Systematic Review
OAK 3 - Non-arthroplasty tx of OAK
Objective: We investigated the reasons and rates of attrition in knee osteoarthritis trials through a systematic review of randomized, placebo-controlled, clinical trials. Methods: Randomized trials were identified by searches conducted in MEDLINE, SCOPUS, and the Cochrane Central Register of Controlled Trials. We then...
0
Tumor necrosis factor-alpha polymorphism, bone strength phenotypes, and the risk of fracture in older women
Management of Hip Fractures in the Elderly
TNFalpha is a proinflammatory cytokine that promotes osteoclastic bone resorption. We evaluated the association between a G-308A polymorphism (rs1800629) at the TNFA locus and osteoporosis phenotypes in 4306 older women participating in the Study of Osteoporotic Fractures. Femoral neck bone mineral density (BMD) and st...
0
Pin-tract infection during limb lengthening using external fixation
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
We evaluated the incidence of pin-tract infection (PTI) during limb lengthening using external fixation in 88 patients and the effects of infection on final outcomes and incidence of additional procedures. The PTI rate was 96.6%. The rate of half-pin site infection was significantly (P<.05) higher in half-pin fixators ...
0
Spatial contrast sensitivity in benign intracranial hypertension
Upper Eyelid and Brow Surgery
Spatial Contrast Sensitivity (CS) was studied in 20 patients with benign intracranial hypertension (BIH). At presentation CS loss was found in 43% of the eyes, and impairment of visual acuity attributed to BIH in only 16%. Nine patients had blurred vision or visual obscurations, all of whom had abnormal CS. The clinica...
0
Risk factors, locations of the thrombus, prophylaxis, and treatment of the deep venous thrombosis patients in the Izmir City and Aegean Region: Results of a multicenter study
Management of Hip Fractures in the Elderly
Objective: To determine whether there is a relationship between the risk factors and the locations of the thrombi, pharmacological prophylaxis, and the treatment modalities in patients with deep venous thrombosis (DVT) in the Izmir City and Aegean Region. Material and Method: We enrolled 531 consecutive patients with D...
0
Reliability of the painDETECT questionnaire in patients with knee osteoarthritis-a descriptive study
Surgical Management of Osteoarthritis of the Knee CPG
Background. The painDETECT questionnaire (PD-Q) is used as a screening tool for the identification of neuropathic pain (NeP). It consists of seven weighted pain descriptors and two pain specific behavioural pattern questions. The questionnaire has been employed in patients with knee osteoarthritis, however its reliabil...
0
Costs and consequences of hip fracture occurrence in old age: an economic perspective
Management of Hip Fractures in the Elderly
PURPOSE: To summarize the reported short- and long-term costs associated with hip fracture occurrence in old age, based on a systematic literature review of published studies. A further aim is to provide a clinician-oriented discussion of the different types of economic evaluations, with an emphasis on studies that exa...
0
Outcomes After Hip Fracture Surgery Compared With Elective Total Hip Replacement
Hip Fx in the Elderly 2019
IMPORTANCE: Patients undergoing surgery for a hip fracture have a higher risk of mortality and major complications compared with patients undergoing an elective total hip replacement (THR) operation. The effect of older age and comorbidities associated with hip fracture on this increased perioperative risk is unknown. ...
0
The association of meniscal damage with joint effusion in persons without radiographic osteoarthritis: the Framingham and MOST osteoarthritis studies
AMP (Acute Meniscal Pathology)
OBJECTIVE: To assess the cross-sectional association between meniscal status and joint effusion on magnetic resonance imaging (MRI) in knees without radiographic osteoarthritis (OA). DESIGN: Knees without OA (Kellgren/Lawrence grade 0) from the Framingham and MOST studies were examined by MRI. Meniscal status was asses...
0
Neurological Complications Related to Elective Orthopedic Surgery: Part 2: Common Hip and Knee Procedures
AAHKS (8) Anesthetic Infiltration
UNLABELLED: Many anesthesiologists may not be familiar with the rate of surgical neurological complications of the hip and knee procedures for which they are providing local anesthetic-based anesthesia and/or analgesia. Part 2 of this narrative review series on neurological complications of elective orthopedic surgery ...
0
Surgical approaches for osteoarthritis
Developmental Dysplasia of the Hip 2020 Review
Patients with osteoarthritis (OA) often benefit from properly performed surgical procedures. However, the scientific database from studies investigating appropriate timing of surgery, patient morbidity, quality of life before and after the intervention, and cost utility of different procedures is insufficient. In order...
0
Predictive factors of hospital stay, mortality and functional recovery after surgery for hip fracture in elderly patients
Hip Fx in the Elderly 2019
OBJECTIVES: Due to its high prevalence and serious consequences it is very important to be well aware of factors that might be related to medical complications, mortality, hospital stay and functional recovery in elderly patients with hip fracture. MATERIAL AND METHODS: A prospective study of a group of 130 patients ag...
0
Role of Autologous Fat Transfer to the Superficial Fat Compartments for Perioral Rejuvenation
Panniculectomy & Abdominoplasty CPG
BACKGROUND: Autologous fat transfer to the deep compartments of the face has proven to be a powerful adjunct to volume restoration during rhytidectomy. However, to treat all components of volume deflation in facial aging, the perioral superficial compartments must be addressed. Various fillers have been used to augment...
0
Prophylactic carpal tunnel decompression during buttress plating of the distal radius - Is it justified?
Distal Radius Fractures
Our objective was to evaluate the role of carpal tunnel decompression in preventing median nerve dysfunction after buttress plating of the distal radius. We studied 69 consecutive patients with distal radial fractures managed by volar plating over a 4-year period. (1995-1998). Patients' clinical notes were assessed for...
0
Ophthalmic complications of dengue
Upper Eyelid and Brow Surgery
We report 13 cases of ophthalmic complications resulting from dengue infection in Singapore. We performed a retrospective analysis of a series of 13 patients with dengue fever who had visual impairment. Investigations included Humphrey automated visual field analyzer, Amsler charting, fundus fluorescein angiography, an...
0
The treatment of osteoarthritis with unconstrained and constrained knee prostheses
Surgical Management of Osteoarthritis of the Knee CPG
The first cases of knee prosthesis implantation at the orthopaedic department of the Freiburg university hospital are discussed. Surgery was indicated by advanced osteoarthritis which showed no improvement under conservative treatment. Indications concerning the choice of knee joint replacement with unconstrained or co...
0
Requirements for DXA for the management of osteoporosis in Europe
Management of Hip Fractures in the Elderly
The availability of dual energy X-ray absorptiometry (DXA) varies markedly in different countries. There is, however, little information to indicate the optimal requirements for this technology. The principal aim of this study was to estimate the requirements for DXA in Europe for the assessment and treatment of osteop...
0
An Overview and Predictors of Achieving the Postoperative Ceiling Effect of the WOMAC Score Following Total Knee Arthroplasty
OAK 3 - Non-arthroplasty tx of OAK
Background: To describe the ceiling effect for the components of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score and identify preoperative independent predictors for patients who achieve maximal scores (ceiling effect) after total knee arthroplasty (TKA). Methods: A retrospective cohort...
0
Pediatric sports injuries: an age comparison of children versus adolescents
Diagnosis and Treatment of Osteochondritis Dissecans AUC
BACKGROUND: Significant knowledge deficits exist regarding sports injuries in the young child. Children continue to engage in physically demanding, organized sports to a greater extent despite the lack of physical readiness, predisposing themselves to injury. PURPOSE: To evaluate sports injuries sustained in very young...
1
Antimicrobials in dermatologic surgery: facts and controversies
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
The two main uses of antimicrobials in dermatologic surgery include prophylaxis for bacteremia and prevention of localized surgical skin infection (LSSI). Bacteremia can result in hematogenous surgical infections such as infective endocarditis and prosthetic joint infection. Comprehensive guidelines from the American H...
0
The fake unlocked femoral nail: A configuration to avoid in stable pertrochanteric femur fractures
Hip Fx in the Elderly 2019
BACKGROUND: Intramedullary unlocked nailing is a safe and used treatment for stable pertrocantheric fractures. Due to the femoral anterior bow of the shaft or a wrong entry point, the distal tip of the nail can be impinging the anterior cortex. This type of situation can compromise the function of the nail, leading to ...
0
Compartment syndrome after total knee arthroplasty: regarding a clinical case
AAHKS (9/10) Regional Nerve Blocks
Although compartment syndrome is a rare complication of total knee arthroplasty, it is one of the most devastating complications. It is defined as a situation of increased pressure within a closed osteofascial space that impairs the circulation and the functioning of the tissues inside this space, thereby leading to is...
0
The immediate antimicrobial effect of a toothbrush and miswak on cariogenic bacteria: A clinical study
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
The aim of this study was to assess the antimicrobial activity of the miswak chewing stick (Salvadora persica) in vivo, especially on streptococcus mutans and lactobacilli. The study was conducted clinically using patients' saliva and measuring the effect of miswak (chewing stick), miswak extract, toothbrush, and norma...
1
Carpal tunnel syndrome: the correlation between outcome, symptoms and nerve conduction study findings
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
A retrospective study was performed on 62 patients who had undergone carpal tunnel decompression surgery. Each patient was assessed in clinic, their case notes were reviewed and their electrophysiological results were analysed and graded according to severity. The median preoperative duration of symptoms was 2 years. N...
0
Hip fracture: How to improve the outcome
Hip Fx in the Elderly 2019
Hip fracture affects mainly the elderly. Because of multiples comorbidities of these patients, the outcome is poor. Hip fracture remains a challenge for physicians taking care of these patients. However, the outcome can be improved by applying a multidisciplinar and multiprofessionnal clinical pathway, describing all t...
0
Management of septic non-union of the tibia by the induced membrane technique. What factors could improve results?
DoD SSI (Surgical Site Infections)
INTRODUCTION: Management of septic non-union of the tibia requires debridement and excision of all infected bone and soft tissues. Various surgical techniques have been described to fill the bone defect. The "Induced Membrane" technique, described by A. C. Masquelet in 1986, is a two-step procedure using a PMMA cement ...
0
Acute compartment syndrome
DOD - Acute Comp Syndrome CPG
BACKGROUND: acute compartment syndrome (ACS) is one of the few true emergencies in orthopedics and traumatology. It is a painful condition caused by the increase interstitial pressure (intracompart-mental pressure - ICP) within a closed osteofascial compartment which impair local circulation. It occurs most often in th...
0
Prognostic factors in adult soft tissue sarcoma treated with surgery combined with radiotherapy: a retrospective single-center study on 164 patients
MSTS 2022 - Metastatic Disease of the Humerus
The aim of the present study is to assess the disease profile, outcome and prognostic factors in patients treated with surgery combined with radiotherapy (RT), with or without chemotherapy (CXT), for soft-tissue sarcoma (STS) in a multidisciplinary setting. One hundred and sixty-four patients with STS treated between 1...
0
Phenotype and genotype in 103 patients with tricho-rhino-phalangeal syndrome
Hip Fx in the Elderly 2019
Tricho-rhino-phalangeal syndrome (TRPS) is characterized by craniofacial and skeletal abnormalities, and subdivided in TRPS I, caused by mutations in TRPS1, and TRPS II, caused by a contiguous gene deletion affecting (amongst others) TRPS1 and EXT1. We performed a collaborative international study to delineate phenotyp...
0
A long term clinical outcome of the Medial Pivot Knee Arthroplasty System
OAK 3 - Non-arthroplasty tx of OAK
Background The ideal total knee arthroplasty (TKA) should provide maximum range of motion and functional stability for all desired daily activities and, if possible, to replicate normal knee kinematics and function. The ADVANCE® Medial Pivot (AMP) Knee System was designed with a highly congruent medial compartment and...
0
Clinical trial on preventive effect of calcitonin to Complex Regional Pain Syndrome (CRPS) associated with distal radius fracture
Distal Radius Fractures
INTERVENTION: Intervention group: Patients receive 4 intramuscular injections of 20U of elcatonin weekly. Control group: Only treatment and rehabilitation for distal radius fracture is performed. CONDITION: distal radius fracture PRIMARY OUTCOME: the presence of complex regional syndrome at any time within three months...
0
Adlea (ALGRX-4975), an injectable capsaicin (TRPV1 receptor agonist) formulation for longlasting pain relief
Glenohumeral Joint OA
Anesiva Inc is developing Adlea (ALRGX-4975) - an injectable preparation of capsaicin, a TRPV1 (transient receptor potential vanilloid subfamily 1) receptor agonist - for the potential management of pain associated with osteoarthritis, tendonitiand postsurgical conditions, as well as for neuropathic pain occurring seco...
0
Omega-3 fatty acids reduce post-operative risk of deep vein thrombosis and pulmonary embolism after surgery for elderly patients with proximal femoral fractures: a randomized placebo-controlled, double-blind clinical trial
Hip Fx in the Elderly 2019
BACKGROUND: Elderly patients with proximal femoral fractures face elevated risk of post-operative deep vein thrombosis and pulmonary embolism, due to the lack of suitable treatment plans after surgery and hospital discharge. This study aimed to investigate the effect of omega-3 fatty acid supplementation in the above-d...
0
Is radiographic measurement of bony landmarks reliable for lateral meniscal sizing?
AMP (Acute Meniscal Pathology)
BACKGROUND: The accuracy of meniscal measurement methods is still in debate. HYPOTHESIS: The authors' protocol for radiologic measurements will provide reproducible bony landmarks, and this measurement method of the lateral tibial plateau will correlate with the actual anatomic value. STUDY DESIGN: Controlled laborator...
0
Ankle Fracture Fixation with Use of WALANT (Wide Awake Local Anesthesia with No Tourniquet) Technique: An Attractive Alternative for the Austere Environment
DoD SSI (Surgical Site Infections)
BACKGROUND: Wide awake local anesthesia with no tourniquet (WALANT) is a simple technique that has had successful application in hand surgery. When utilized in the plating of distal radial fractures, the WALANT technique has proven to be a cost-effective approach in orthopaedic trauma. The aim of the present study was ...
1
Fixation of displaced femoral neck fractures in young adults: Fixed-angle devices or Pauwel screws?
Hip Fx in the Elderly 2019
BACKGROUND: We sought to compare the incidence of complications after fixation of displaced femoral neck fractures in young adults treated with fixed-angle devices versus multiple cancellous screws and a trochanteric lag screw (Pauwel screw). METHODS: We conducted a retrospective cohort study at a level I trauma centre...
0
Calcium deposition in osteoarthritic meniscus and meniscal cell culture
Surgical Management of Osteoarthritis of the Knee CPG
INTRODUCTION: Calcium crystals exist in the knee joint fluid of up to 65% of osteoarthritis (OA) patients and the presence of these calcium crystals correlates with the radiographic evidence of hyaline cartilaginous degeneration. This study sought to examine calcium deposition in OA meniscus and to investigate OA menis...
1
Early complications associated with cephalomedullary nail for intertrochanteric hip fractures
Management of Hip Fractures in the Elderly
BACKGROUND: Use of cephalomedullary devices for pertrochanteric fractures has been associated with complications of cutout, fracture distal to the tip of the implant, infection, and hardware failure. The goal of recent design changes (a trapezoidal shape of the proximal device, with interdigitation of the cephalocervic...
0
The influence of sacral morphology on the existence of secure S1 and S2 transverse bone corridors for iliosacroiliac screw fixation
Hip Fx in the Elderly 2019
Sacroiliac (SI) screw fixation for unstable pelvic fractures stands out as the only minimally invasive method among all other ORIF procedures. A strictly transverse screw trajectory is needed for central or bilateral fracture patterns up to a complete iliosacroiliac fixation. However, secure screw insertion is aggravat...
0
Rates, patterns, causes, and costs of hospitalization of nursing home residents: A population-based study
HipFx Supplemental Cost Analysis
Objectives. Hospitalization of nursing home residents is a growing, poorly defined problem. The purposes of this study were to define rates, patterns, costs, and outcomes of hospitalizations from nursing homes and to consider implications for reducing this problem as part of health care reform. Methods. Communitywide n...
0
Septic versus aseptic hip revision: how different?
PJI DX Updated Search
BACKGROUND: The few available studies directly comparing aseptic and septic joint revision surgery report conflicting results. We investigated whether two-stage revision of septic hip prosthesis with a preformed antibiotic-loaded spacer and an uncemented prosthesis provides hip function and quality of life similar to t...
0
Trauma to the elbow and forearm
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
Elbow and forearm trauma constitute a significant percentage of upper extremity injuries. A thorough understanding of the anatomy and mechanism of injury is necessary for obtaining the most accurate radiographic interpretation in both the pediatric and adult populations. Proper radiographic positioning and choice of th...
0
Injuries associated with traumatic anterior glenohumeral dislocations
Management of Hip Fractures in the Elderly
BACKGROUND: A number of shoulder girdle injuries are associated with acute anterior glenohumeral dislocations. In the present study we evaluated the prevalence of neurological deficits, greater tuberosity fractures, and rotator cuff injuries in a population of unselected patients who presented with a traumatic anterior...
0
Bizarre parosteal osteochondromatous proliferation of bone: clinical management of a series of 22 cases
Diagnosis and Treatment of Osteochondritis Dissecans AUC
We describe 22 cases of bizarre parosteal osteochondromatous proliferation, or Nora's lesion. These are surface-based osteocartilaginous lesions typically affecting the hands and feet. All patients were identified from the records of a regional bone tumour unit and were treated between 1985 and 2009. Nine lesions invol...
0
Arthroplasty of the hip in patients with aplastic anemia
Management of Hip Fractures in the Elderly
BACKGROUND: Patients with aplastic anemia are now living longer and therefore are at increased risk for the development of osteonecrosis of the hip. However, studies on the results of arthroplasty for the treatment of osteoarthritis of the hip in patients with aplastic anemia are lacking. METHODS: Twenty-six primary hi...
0
Distractor modulation of saccade trajectories: Spatial separation and symmetry affects
Upper Eyelid and Brow Surgery
The trajectories of saccadic eye movements can be modulated by the presence of a competing visual distractor. In the present study the trajectories of vertical saccades curved away from a single visual distractor presented in one visual field, but tended to be straight when two distractors were presented at mirror symm...
0
Oral care interventions and oropharyngeal colonization in children receiving mechanical ventilation
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
BACKGROUND: Recent progress in identification of oral microorganisms has shown that the oropharynx can be a site of origin for dissemination of pathogenic organisms to distant body sites, such as the lungs. OBJECTIVE: To compare the oropharyngeal microbiological profile, duration of mechanical ventilation, and length o...
1
Study on the external fixator in the treatment of the fractures of the inferior end of the two bones of the adult's forearm. Report of fifty-five cases
Distal Radius Fractures
The authors report 55 cases of fracture with significant displacement of the distal end of the radius. In 30 cases, there were, moreover, lesions of adjacent bones and in 18 cases, lesions of the soft tissues. The fractures were treated by Hoffmann external fixator placed either immediately or later on, after the failu...
0
Long-term results of total hip arthroplasty for femoral neck fracture nonunion
Management of Hip Fractures in the Elderly
BACKGROUND: Hip arthroplasty for the treatment of nonunion at the site of a femoral neck fracture has provided good short-term results. The purpose of the present study was to evaluate the long-term results and complications of total hip arthroplasty for the treatment of femoral neck nonunion. METHODS: The records of n...
0
Skeletal manifestations of polymyalgia rheumatica
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
In a review of 39 patients with polymyalgia rheumatica (PMR), sternoclavicular and acromioclavicular arthropathy was noted in 15% and 10% of the patients, respectively. Diffuse clavicular swelling preceded the onset of PMR in one patient. Carpal tunnel syndrome was seen in four patients (10%)
0
Type of anaesthesia and the safety and efficacy of thromboprophylaxis with enoxaparin or dabigatran etexilate in major orthopaedic surgery: pooled analysis of three randomized controlled trials
Surgical Management of Osteoarthritis of the Knee CPG
BACKGROUND: There has been a shift towards greater use of neuraxial over general anaesthesia for patients undergoing total hip or knee arthroplasty. Furthermore, suggestions that peripheral nerve block may reduce adverse effects have recently been put forward. Although older studies showed a reduction in venous thrombo...
0
Immunodeficiency and immunotherapy in multiple myeloma
MSTS 2018 - Femur Mets and MM
Multiple myeloma is a malignant tumour of plasma cells that remains incurable for the vast majority of patients, with a median survival of 2-3 years. It is characterized by the patchy accumulation of tumour cells within bone marrow leading to variable anaemia, bone destruction, hypercalcaemia, renal failure and infecti...
0
Chronic osteomyelitis in Ilorin, Nigeria
DoD SSI (Surgical Site Infections)
AIM: To review cases of chronic osteomyelitis managed at a private health institution (Ela Memorial Medical Centre, Ilorin, Nigeria) between March 1995 and February 2005. RESULTS: Of the 107 cases, 71 (66.4%) were males, with a male-to-female ratio of 2:1. The mean age was 21.9 years (range 1.5 - 80 years). Chronic ost...
0
The ulnar side of the wrist: Clinically relevant anatomy and biomechanics
Distal Radius Fractures
Background In the hectic environment of a hand therapy clinic, the opportunity to carefully consider the relationships among pathology, pathomechanics, surgical repair techniques, tissue healing, postoperative management, and rehabilitation program development and progression is limited. Clinicians often default to see...
1
Mortality analysis in hip fracture patients: implications for design of future outcome trials
Management of Hip Fractures in the Elderly
INTRODUCTION: Patients with hip fractures are usually frail and elderly with a 30-day mortality in excess of 10% in European series. Perioperative morbidity is often multifactorial in nature, and unimodal interventions will not necessarily decrease mortality. The purpose of this prospective study was to analyse causes ...
0
Effects of mouth rinses with xylitol and fluoride on dental plaque and saliva
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
The aim of this study was to test the hypothesis that xylitol, alone and in combination with fluoride, affects the salivary flow rate and micro-biota, dental plaque accumulation, gingivitis development, and the acidogenic potential of plaque. Three groups, each of 10 subjects, rinsed for 1 min 3 times daily over two 4-...
0
Evidence-based medicine: liposuction
Panniculectomy & Abdominoplasty CPG
LEARNING OBJECTIVES: After reading this article, the participant should be able to: 1. Perform preoperative assessment and patient selection for liposuction surgeries. 2. Explain the differences among the various types of anesthesia and wetting solutions used in liposuction. 3. Identify the available literature about s...
0
Incidence of intravenous patient controlled analgesia and controlled release opioids initiation following total knee arthroplasty
Surgical Management of Osteoarthritis of the Knee CPG
AIM: The objective of this quality assurance review is to describe the postoperative pain management practices of the Acute Pain Service at our tertiary care academic hospital (Toronto Western Hospital) in the total knee arthroplasty (TKA) population. In particular, we sought to determine the percentage of patients who...
0
Multilevel Cervical Spondylosis
Glenohumeral Joint OA
Optimal management of patients presenting with multilevel cervical spondylotic disease requires a comprehensive and individualized approach. The potential for complications exists at each step. Appropriate patient selection, careful evaluation of preoperative imaging, an optimal surgical strategy, and proper execution ...
0
Antimicrobial efficacy of a new antibiotic-loaded poly(hydroxybutyric-co-hydroxyvaleric acid) controlled release system
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
OBJECTIVE: Failure of orthopaedic devices, mainly femoral hip replacements, due to infection is of increasing medical importance. There is a need for improved antibiotic delivery systems in the treatment of orthopaedic infections and here we have evaluated polyhydroxyalkanoate formulations for their suitability as a co...
0
Association of bone mineral density and vertebral deformity in patients with rheumatoid arthritis
Management of Hip Fractures in the Elderly
The aim of this study was to investigate the association of vertebral deformities developed as a result of osteoporosis in female patients with rheumatoid arthritis (RA) with bone mineral density (BMD) and disease activity parameters. In the study, 100 female patients with the diagnosis of RA and 56 healthy subjects we...
0
Torsional malalignment, how much significant in the trochanteric fractures?
Hip Fx in the Elderly 2019
OBJECTIVES: The rotational alignment is definitely important in the long bones such as tibias and femurs. We also predict the importance of rotational alignment in the trochanteric fractures. So we measured torsional malalignment in trochanteric fracture and anlaysed their risk factors and their clinical significance. ...
1
Prospective Study of Closed Reduction of Trochanteric Fractures via a Novel Intraoperative Femoral Fracture Reduction Device: Early Clinical Results
Hip Fx in the Elderly 2019
OBJECTIVE: Traction achieved using an intraoperative femoral fracture reduction device (IFFRD) was compared with that observed using a traction table (TT) for closed reduction of trochanteric fractures and cephalomedullary nail fixation. DESIGN: Prospective cohort study. SETTING: Level 1 trauma center. PATIENTS: One hu...
0
Effect of an essential oil-containing dentifrice on dental plaque microbial composition
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
PURPOSE: To determine the effect of 6 months use of an essential oil-containing (EO) antiplaque/antigingivitis fluoride dentifrice on the balance of the oral microbial flora and on the emergence of resistant microbial forms by analysis of dental plaque and saliva. MATERIALS AND METHODS: The dentifrice essential oils co...
0
The frequency and management of asparaginase-related thrombosis in paediatric and adult patients with acute lymphoblastic leukaemia treated on Dana-Farber Cancer Institute consortium protocols
DOD - Acute Comp Syndrome CPG
The optimal management of asparaginase-associated thrombotic complications is not well-defined. We report the features, management and outcome of paediatric (ages 0-18years) and adult (18-50years) patients with acute lymphoblastic leukaemia (ALL) with asparaginase-related venous thromboembolic events (VTE) treated at D...
0
Internal fixation versus cemented hemiarthroplasty for displaced femoral neck fractures in patients with severe cognitive dysfunction: A randomized controlled trial
DoD SSI (Surgical Site Infections)
OBJECTIVES:: To compare the outcome of internal fixation (IF) versus a cemented hemiarthroplasty (HA) in patients with a displaced femoral neck fracture and a severe cognitive dysfunction. DESIGN:: A prospective randomized controlled trial. SETTING:: A tertiary care university hospital. PATIENTS:: Sixty patients with a...
0
Risk factors for secondary meniscus tears can be accurately predicted through machine learning, creating a resource for patient education and intervention
AMP (Acute Meniscal Pathology)
PURPOSE: This study sought to develop and internally validate a machine learning model to identify risk factors and quantify overall risk of secondary meniscus injury in a longitudinal cohort after primary ACL reconstruction (ACLR). METHODS: Patients with new ACL injury between 1990 and 2016 with minimum 2-year follow-...
0
Influence of Depressive Symptoms on the Clinical Outcomes of Total Ankle Arthroplasty
OAK 3 - Non-arthroplasty tx of OAK
Many studies have reported the relevance of depression on clinical outcomes after knee or hip arthroplasty. However, no study has investigated this relationship in total ankle arthroplasty (TAA). This study aimed to study the relationship between depressive symptoms and clinical outcomes after TAA. This retrospective c...
0
Impact of COVID-19 on the Reported Case Volume of Orthopaedic Sports Medicine Fellows in the United States
AMP (Acute Meniscal Pathology)
Background: The impact of the coronavirus 2019 (COVID-19) pandemic on reported case volume during orthopaedic sports medicine fellowship training remains poorly understood from a national perspective. Hypothesis: It was hypothesized that reported case volume during orthopaedic sports medicine fellowship training would ...
1
The use of prophylactic flucloxacillin in treatment of open fractures of the distal phalanx within an accident and emergency department: a double-blind randomized placebo-controlled trial
DoD SSI (Surgical Site Infections)
Open fractures of the distal phalanx commonly present to the Accident and Emergency Department. Controversy surrounds the use of prophylactic antibiotics in treating this injury. A double-blind, prospective, randomized placebo-controlled study was undertaken comparing the use of prophylactic flucloxacillin to placebo i...
0
Surgical interventions for early structural knee osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the benefits and harms of surgical intervention for the management of early structural knee osteoarthritis.
0
Comparative evaluation of postreduction intra-articular distal radial fractures by radiographs and multidetector computed tomography
Distal Radius Fractures
BACKGROUND: Computed tomography can be an adjunct to radiographs when evaluating intra-articular fractures of the distal part of the radius. Acute-phase multidetector computed tomography has better temporal, spatial, and contrast resolution than a conventional scanner has. The aim of this study was to determine prospec...
0
Where does pelvic and acetabular fracture treatment fit into the newly proposed major trauma model in Ireland?
Hip Fx in the Elderly 2019
Aim To provide the most up to date reference of referral patterns for pelvis and acetabular (PA) fractures in Ireland and discuss where services should ideally be located. Methods A retrospective review was conducted of all referrals to the national referral centre for PA fractures in Ireland for 2016 and 2017. Results...
0
Sense of coherence moderates late effects of early childhood Holocaust exposure
DoD PRF (Psychosocial RF)
This study evaluated child Holocaust survivors with an emphasis on potential protective factors facilitating participants' adaptation to post-Holocaust life. We examined Antonovsky's (1979, 1987) salutogenic paradigm, testing the mediating and moderating effect of participants' sense of coherence (SOC) on the associati...
0
Systemic effects of periodontitis
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
This literature review summarizes current knowledge on the systemic levels of selected markers of inflammation in periodontitis. From the available literature it appears that the total numbers of leukocytes and plasma levels of C-reactive protein (CRP) are consistently higher in periodontitis patients compared with hea...
0
A comparison between the Major Trauma Centre management of complex open lower limb fractures in children and the elderly
DoD SSI (Surgical Site Infections)
INTRODUCTION: Open lower limb fractures can be devastating with outcomes determined by tissue damage and adherence to strictly defined care pathways. Managing such injuries in paediatric and elderly populations presents logistical and technical challenges to achieve best outcomes. Orthoplastic principles were developed...
1
The challenge of Monteggia-like lesions of the elbow: Mid-term results of 46 cases
DoD SSI (Surgical Site Infections)
Aims The aim of this retrospective multicentre study was to evaluate mid-term results of the operative treatment of Monteggia-like lesions and to determine the prognostic factors that influence the clinical and radiological outcome. Patients and Methods A total of 46 patients (27 women and 19 men), with a mean age of 5...
1
Effects of cemented versus press-fit primary humeral stem fixation in the setting of revision shoulder arthroplasty
Trial Systematic Review Project
Background: The influence of primary humeral stem fixation method (cemented or press fit) on intraoperative or postoperative outcomes in the setting of revision shoulder arthroplasty is unknown. Methods: A retrospective analysis of a prospectively collected cohort of revision shoulder arthroplasty patients from a singl...
0
Race/ethnicity and outcomes following inpatient rehabilitation for hip fracture
Management of Hip Fractures in the Elderly
BACKGROUND: Hip fracture results in severe and often permanent reductions in overall health and quality of life for many older adults. As the U.S. population grows older and more diverse, there is an increasing need to assess and improve outcomes across racial/ethnic cohorts of older hip fracture patients. METHODS: We ...
0
Arm pain in a dentist: pronator syndrome
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
A 29-year-old pregnant dentist developed acute right forearm pain and associated weakness in her hand. A diagnosis of pronator syndrome was made. A review of the anatomy, pathophysiology, and treatment of pronator syndrome is given. We present this case to alert dentists, both male and female, of an uncommon but defini...
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Recovery of joint position sense after total knee replacement: the effects of soft tissue dissection
Surgical Management of Osteoarthritis of the Knee CPG
To find out the effect of sharp dissection compared to electrocautery for soft tissue release and balancing in total knee replacement on proprioceptive sense, the study was carried out as a parellel double blind trial with 2 year follow-up. There were 52 patients in the sharp dissection group and 42 patients in the ele...
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Cementless total hip arthroplasty for the management of tuberculosis coxitis
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
Introduction: Tuberculosis arthritis of the hip is a crippling disease and there is need for an effective and acceptable treatment for the hips with bone destruction. The aim of this report was to evaluate the efficacy of the diagnostic method for hip tuberculosis and clinical results of the patients to clarify the que...
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Infection in primary hip arthroplasty after previous steroid infiltration
Surgical Management of Osteoarthritis of the Knee CPG
Steroid Infiltration into arthritic joints is a common means of treating pain. It is also sometimes done to differentiate pain in the hip from that in the low back or knee. We performed a retrospective review of the notes of all patients who had undergone hip replacements in Wrightington Hospital under the care of the ...
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Changes in bone mineral density and bone turnover in patients on 'drug holiday' following bisphosphonate therapy: Real-life clinic setting
Hip Fx in the Elderly 2019
Summary Objectives Treatment discontinuation after long-term bisphosphonate (BP), termed a 'drug holiday', has been proposed to reduce the risk of BP-associated complications. The duration of treatment cessation remains unclear. Changes in bone mineral density (BMD), bone turnover markers (BTMs) and their relationship ...
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Effects of sudden, passive muscle shortening according to Grimaldi's method on patients suffering from multiple sclerosis: a randomized controlled trial
Management of Hip Fractures in the Elderly
PURPOSE: The purpose of this study was to investigate the short-term effect of a therapeutical approach called "Grimaldi's method." The authors hypothesized that Grimaldi's method would improve active muscle recruitment. The treatment was focused on hip abductors. The authors collected data of hip's active range of mot...
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A more stable posterior approach for hemiarthroplasty of the hip
Management of Hip Fractures in the Elderly
The dislocation rate following the insertion of a hemiarthroplasty of the hip via the posterior approach is variously quoted as between 8 per cent and 15 per cent. We set out to determine if this could be reduced by preserving the labrum and capsular structures at the time of surgery. We used a modification of the post...
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Methicillin-resistant Staphylococcus aureus in TKA treated with revision and direct intra-articular antibiotic infusion
PJI DX Updated Search
BACKGROUND: Resistant organisms are difficult to eradicate in infected total knee arthroplasty. While most surgeons use antibiotic-impregnated cement in these revisions, the delivery of the drug in adequate doses is limited in penetration and duration. Direct infusion is an alternate technique. QUESTIONS/PURPOSES: We a...
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FX006 prolongs the residency of triamcinolone acetonide in the synovial tissues of patients with knee osteoarthritis
OAK Recommendation 9 Articles
Purpose: Intra-articular (IA) administration of triamcinolone acetonide injectable suspension (TCA IR) is commonly used to treat pain and inflammation associated with osteoarthritis (OA) of the knee. FX006 is an extended-release IA formulation of TCA in poly(lactic-co-glycolic acid) (PLGA) microspheres that is intended...
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The four medial ankle tunnels: a critical review of perceptions of tarsal tunnel syndrome and neuropathy
DoD LSA (Limb Salvage vs Amputation)
The mechanisms of symptom production (other than a space-occupying lesion) and the diagnosis of tarsal tunnel syndrome remain controversial. To understand the diagnosis and treatment of tarsal tunnel syndrome in the presence of neuropathy, the known anatomy and pathophysiology related to the tarsal tunnel and the exist...
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Correlation of synovial tissue protein abundance with menopause in osteoarthritis
AMP (Acute Meniscal Pathology)
Background: Osteoarthritis (OA) is a common articular disorder. Epidemiologic surveys show a higher prevalence of OA in women than men and that morbidity is higher during menopause. We aimed to explore whether menopause influences the clinical recovery of a knee joint following OA and injury, and identify associated me...
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Antibacterial effect of chlorhexidine- containing glass ionomer cement in vivo: a pilot study
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
This in vivo pilot study was carried out to test the antibacterial effect of glass ionomer containing chlorhexidine (test group) in comparison to conventional glass ionomer (control group). Fifty 6- to 11-year-old children with one occlusal lesion in a molar were randomly allocated to test and control groups in a paral...
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The role of children's routines of daily living, supervision, and maternal fatigue in preschool children's injury risk
DoD PRF (Psychosocial RF)
The purpose of this study was to (a) explore the relationship between the lack of everyday routines and children's unintentional injuries, (b) examine two mechanisms of effect through which lack of routines might operate, children's sleep and maternal supervision, and (c) explore the influence of maternal fatigue in ro...
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Subcutaneous Bioavailability of Taspoglutide at 3 Different Injection Sites in Healthy Overweight/Obese Subjects
DoD SSI (Surgical Site Infections)
Purpose Taspoglutide is a long-acting glucagon-like peptide-1 (GLP-1) receptor agonist that has >90% homology with the endogenous GLP-1 while retaining equivalent potency. Once-weekly subcutaneous injections with taspoglutide demonstrated meaningful antihyperglycemic and weight loss effects in patients with type 2 diab...
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Proximal femoral nail antirotation and third-generation Gamma nail: which is a better device for the treatment of intertrochanteric fractures?
Hip Fx in the Elderly 2019
INTRODUCTION: Proximal femoral nail antirotation (PFNA) and third-generation Gamma nail (Gamma 3) are widely used in the treatment of intertrochanteric fractures. However, it remains unclear which device achieves better clinical and radiographic outcomes when treating intertrochanteric fractures. METHODS: This study co...
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Low-energy subtrochanteric fractures in elderly patients: results of fixation with the sliding screw plate
Management of Hip Fractures in the Elderly
Forty-two patients with subtrochanteric fractures were treated from 1987 through 1990. Of these, 31 patients above 70 years of age (average, 81.9) had nonpathologic low-energy fractures that were internally fixed with a sliding screw-plate device. Subtrochanteric fractures with an associated intertrochanteric component...
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Clinical and demographic factors associated with fractures among older Americans
Management of Hip Fractures in the Elderly
Summary: Medicare claims data were used to investigate associations between history of previous fractures, chronic conditions, and demographic characteristics and occurrence of fractures at six anatomic sites. The study confirmed previously established associations for hip and spine fractures and identified several new...
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Physical Activity and Sexuality After Reduction Mammaplasty
Reduction Mammoplasty for Female Breast Hypertrophy
influence physical activity and sexuality of breast hypertrophy women.This prospective controlled trial was designed to determine whether breast reduction may
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Post-bariatric abdominoplasty: skin sensation evaluation
Panniculectomy & Abdominoplasty CPG
BACKGROUND: The number of bariatric surgeries is progressively increasing in the USA and in Brazil. The number of post-bariatric plastic surgeries also increases as a response to this phenomenon. Abdominoplasties performed in former morbidly obese patients present a larger number of postoperative complications. Studies...
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Hemarthrosis after trauma to the pediatric knee joint: what is the value of magnetic resonance imaging in the diagnostic algorithm?
Anterior Cruciate Ligament Injuries CPG
In children, compulsory arthroscopy for hemarthrosis after knee trauma is not justified because ligamentous and meniscal damage is rare. In a prospective study, we analyzed the diagnostic value of radiography, magnetic resonance imaging (MRI), and arthroscopy in 51 patients up to 14 years of age with acute knee trauma....