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Facilitation of pain sensitization in knee osteoarthritis and persistent post-operative pain: a cross-sectional study
Surgical Management of Osteoarthritis of the Knee CPG
BACKGROUND: Around 20% of patients with osteoarthritis (OA) have chronic post-operative pain after total knee arthroplasty (TKA) and often undergo revision surgery with unfavourable pain outcome. This study compared sensitization in pain patients with knee OA and after revision TKA (re-TKA). METHODS: Median pressure pa...
0
Infrapatellar fat pad of patients with end-stage osteoarthritis inhibits catabolic mediators in cartilage
Surgical Management of Osteoarthritis of the Knee CPG
OBJECTIVE: Adipose tissue is known to release inflammatory cytokines and growth factors. In this exploratory study, the authors examined whether the infrapatellar fat pad (IPFP) closely located to cartilage in the knee joint can affect cartilage metabolism. In addition, the authors analysed whether the macrophage types...
0
Functional outcomes and survivorship of distal femoral osteotomy with cartilage restoration of the knee
AMP (Acute Meniscal Pathology)
Introduction: Few studies have reported on functional outcome and survivorship of simultaneous distal femoral osteotomy (DFO) and cartilage restoration techniques, including lateral femoral condyle osteochondral allograft transplantation (OCA). Objectives: The purpose of this investigation is therefore to evaluate shor...
0
Magnetic resonance imaging of focal articular cartilage lesions
AMP (Acute Meniscal Pathology)
Lesions of the articular cartilage now are recognized as a common, often treatable source of joint disability. Magnetic resonance imaging (MRI) of articular cartilage is a sensitive, noninvasive method for the detection of focal articular cartilage lesions. Advancement in imaging technology now allows for high spatial ...
0
Objective analysis of lateral elbow exposure with the extensor digitorum communis split compared with the kocher interval
Distal Radius Fractures
Background: The most widely used surgical approach to treat radial head fractures is through the Kocher interval. However, the extensor digitorum communis (EDC) splitting approach is thought to allow easier access to the anterior half of the radial head, which is more commonly fractured. The aim of this cadaveric study...
1
Ultra minimally invasive sonographically guided carpal tunnel release: an external pilot study
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
BACKGROUND: Authors have reported better outcomes, by reducing surgical dissection for carpal tunnel syndromes requiring surgery. Recently, a new sonographically guided technique for ultra minimally invasive (Ultra-MIS) carpal tunnel release (CTR) through 1mm incision has been described. HYPOTHESIS: We hypothesized tha...
0
Imaging the knee
AMP (Acute Meniscal Pathology)
• Plain films are adequate for most cases of uncomplicated arthropathies and trauma. • For suspected internal derangement MRI is the optimum technique. Routine plain films are not indicated. • Ultrasound is ideal for initial examination of periarticular swellings and tendon disorders • MRI or CT arthrography is the bes...
0
Comparison of the effectiveness of medicinal leech and TENS therapy in the treatment of primary osteoarthritis of the knee : A randomized controlled trial
OAK 3 - Non-arthroplasty tx of OAK
OBJECTIVES: The aim of this study was to evaluate the effects of leech therapy in the treatment of knee osteoarthritis in terms of duration of effectiveness and symptom relief and to compare these results with transcutaneous electrical nerve stimulation (TENS) therapy. MATERIAL AND METHODS: This study was designed as a...
0
Benzodiazepine use and hip fractures in the elderly: who is at greatest risk?
Management of Hip Fractures in the Elderly
BACKGROUND: It remains unclear whether benzodiazepine use increases hip fracture incidence. We studied this relationship in a large cohort, controlling for multiple potential confounders. METHODS: We analyzed 42 months of New Jersey Medicaid health care claims data for all enrollees. Each eligible person-day was assign...
1
GAPN postacute care coordination improves hip fracture outcomes
Management of Hip Fractures in the Elderly
We tested the effectiveness of a nursing intervention model to improve health, function, and return-home outcomes in elders with hip fracture via a 2-year randomized clinical trial. Thirty three elders (age > 65 years) were tracked from hospital discharge to 12 months postfracture. The treatment group had a gerontologi...
0
The effect of psychological interventions on the prevention of chronic pain in adults: A systematic review protocol
DoD PRF (Psychosocial RF)
Background: Numerous psychological risk and protective factors have been identified as contributing to or preventing the development of the prevalent issue of chronic pain. Systematic reviews of studies on psychological interventions that tackle these factors have shown limited effects on chronic pain. Therefore, imple...
1
Early discharge of hip fracture patients from hospital: transfer of costs from hospital to nursing home
HipFx Supplemental Cost Analysis
Hip fracture patients occupy more and more hospital beds. One of the strategies for coping with this problem is early discharge from the hospital to institutions with rehabilitation facilities. We studied whether early discharge affects outcome and costs. 208 elderly patients with a hip fracture were followed up to 4 m...
0
Quality of post-anesthetic care in a hospital without a Post-Anesthetic Care Unit: A clinical audit
Management of Hip Fractures in the Elderly
Aim. The majority of Italian hospitals are not equipped with a Post-Anesthetic Care Unit. The aim of this study is to evaluate whether it is possible to guarantee post-anesthetic care according to current international quality and safety standards in the absence of such a structure. Methods. Our hospital is not equippe...
0
Non-invasive raman spectroscopic detection of carotenoids in human skin
Panniculectomy & Abdominoplasty CPG
Carotenoids are thought to play a significant part in the skin's anti-oxidant defense system, and may help prevent malignancy. Inability to measure skin carotenoid content readily has, however, made it difficult to establish the relationship between carotenoid concentration and the occurrence of cutaneous malignancy. W...
0
Delayed treatment of type 3 supracondylar humerus fractures in children
DoD SSI (Surgical Site Infections)
A retrospective review of 158 type 3 supracondylar humerus fractures was undertaken to determine whether any correlation exists between an increased time from injury to surgery and four unfavorable results: a longer operative time, an increase in hospital stay, an increase in the need to open the fracture, or an increa...
1
Changes in knee joint load indices from before to 12 months after arthroscopic partial meniscectomy: a prospective cohort study
AMP (Acute Meniscal Pathology)
OBJECTIVE: Patients undergoing arthroscopic partial meniscectomy (APM) are at increased risk of knee osteoarthritis (OA). Meniscal damage and/or surgery may alter knee joint loading to increase OA risk. We investigated changes in knee joint loading following medial APM surgery, compared with the contra-lateral leg. MET...
0
Expert consensus on Pulmonary Function Testing during the epidemic of Corona Virus Disease 2019
Coronavirus Disease 2019 (COVID-19)
Corona virus disease 2019 (COVID-19) is mainly transmitted by respiratory droplets and close contact. Pulmonary function testing procedures have been associated with an increasing risk of COVID-19 transmission among patients/subjects and medical staffs. Effective prevention and control strategies must be compulsorily i...
0
Surgery for incarcerated hernia: short-term outcome with or without mesh
PJI DX Updated Search
BACKGROUND: Incarcerated hernias represent about 5-15 % of all operated hernias. Tension-free mesh is the preferred technique for elective surgery due to low recurrence rates. There is however currently no consensus on the use of mesh for the treatment of incarcerated hernias, especially in case of bowel resection. AIM...
0
Unusual complication associated with femoral intramedullary alignment guide in total knee arthroplasty
Surgical Management of Osteoarthritis of the Knee CPG
The few reported complications related to the use of a femoral intramedullary alignment guide in total knee arthroplasty include increase in perioperative bleeding and fat embolism. We report 3 patients suffering from an unusual complication, concerning trapping of the tibial locking pin inside the intramedullary canal...
0
Unipedal standing exercise and hip bone mineral density in postmenopausal women: A randomized controlled trial
Management of Hip Fractures in the Elderly
The aim of this study was to test the effect of unipedal standing exercise on bone mineral density (BMD) of the hip in postmenopausal women. Japanese postmenopausal women (n = 94) were assigned at random to an exercise or control group (no exercise). The 6-month exercise program consisted of standing on a single foot f...
0
Genetic contributions to pain: A review of findings in humans
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Pain represents the major motivating factor for which individuals seek healthcare, and pain responses are characterized by substantial inter-individual differences. Increasing evidence suggests that genetic factors contribute significantly to individual differences in responses to both clinical and experimental pain. T...
1
Objective integrated assessment of functional outcomes in reduction mammaplasty
Reduction Mammoplasty for Female Breast Hypertrophy
BACKGROUND: The aim of our study was an objective integrated assessment of the functional outcomes of reduction mammaplasty. METHODS: The study involved 17 women undergoing reduction mammaplasty from March 2009 to June 2011. Each patient was assessed before surgery and 2 months postoperatively with the original associa...
0
Mobilization of human immature hematopoietic progenitors through combinatory use of bortezomib and immunomodulatory drugs
MSTS 2018 - Femur Mets and MM
Combination use of the proteasome inhibitor bortezomib and the immunomodulatory drugs lenalidomide or thalidomide has provided superior outcomes in multiple myeloma over their single use; however, these combinations can produce significant toxicities. Unexpectedly, we found a small but significant increase in the popul...
0
Reconstruction with endoprosthesis in gonarthrosis: a report of 111 consecutive cases operated upon from 1973 through 1977
Surgical Management of Osteoarthritis of the Knee CPG
The results of reconstruction with 3 standard knee joint endoprostheses in advanced gonarthrosis are reported prospectively for 111 consecutive cases operated upon during the years 1973 through 1977 according to a consecutive, precise routine. High tibial osteotomy was indicated in the early stages of the disease, i.e....
1
External Fixation Versus Volar Locking Plate for Unstable Dorsally Displaced Distal Radius Fractures-A 3-Year Follow-Up of a Randomized Controlled Study
Distal Radius Fractures
PURPOSE: To determine if a volar locking plate (VLP) is superior to external fixation (EF) 3 years after surgery for unstable, dorsally displaced, distal radius fractures caused by low-energy injury in patients 50 to 74 years of age. METHODS: During 2009 to 2013, 140 patients with an unstable dorsally displaced distal ...
0
Superficial liposuction: a new application of the technique for aged and flaccid skin
Panniculectomy & Abdominoplasty CPG
From 1982 to 1991, 2500 patients underwent liposuction to thin the superficial areolar layer of fat. The patients were of all ages and had different types of skin. From the results the author concludes that the new superficial liposculpting, based on the controlled scar retraction of the thin cutaneous adipose flap rem...
0
International variations in hip fracture probabilities: implications for risk assessment
Management of Hip Fractures in the Elderly
It is recommended that intervention thresholds should be based on absolute fracture risk, but there is a large variation in hip fracture incidence from different regions of the world. The aim of this study was to examine heterogeneity of hip fracture probability in different regions from recent estimates of hip fractur...
0
Growth hormone deficiency in the transition period: Body composition and gonad function
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Recombinant GH therapy is normally administered to GH-deficient children in order to achieve a satisfactory height - the main target during childhood and adolescence. However, the role of GH does not end once final height has been reached, but continues during the so-called transition period. In this phase of life, the...
0
Bone loss after initiation of androgen deprivation therapy in patients with prostate cancer
Management of Hip Fractures in the Elderly
CONTEXT: Although androgen deprivation therapy (ADT) for prostate cancer is associated with bone loss, little is known about when this bone loss occurs. OBJECTIVE: We postulated that men on ADT would experience the greatest bone loss acutely after initiation of ADT. DESIGN AND SETTING: We conducted a 12-month prospecti...
0
Clinical issues in the prevention of dental-induced endocarditis and prosthetic joint infection
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
No issue in medicine or dentistry is the subject of more misunderstanding than the prevention of infective endocarditis and late prosthetic joint infections. To resolve some of the confusion, national medical groups have published guidelines for the prevention of these infections, including the use of antibiotic prophy...
0
The Effect of Early Progressive Resistive Exercise Therapy on Balance Control of Patients with Total Knee Arthroplasty
OAK 3 - Non-arthroplasty tx of OAK
Background and Purpose: Although total knee arthroplasty (TKA) is a common treatment for severe osteoarthritis, high risks of fall and balance loss are the main complications of this procedure. While multiple rehabilitation protocols have been suggested for TKA, efficacy of early resistive exercise therapy aimed at imp...
0
Analysis of the prognostic factors of extensive disease small-cell lung cancer patients in tokushima university hospital
MSTS 2018 - Femur Mets and MM
Background: Small-cell lung cancer (SCLC) presents aggressive clinical behavior, and its prognosis is still poor. Previously, performance status (PS), or the existence of brain, bone, or liver metastasis were reported to be unfavorable prognostic factors. Given the recent progress of treatment modalities such as radiot...
1
Torticollis and hip dislocation
Developmental Dysplasia of the Hip CPG
Reports in the literature suggest that there is an association between two childhood disorders: torticollis, an easily recognized clinical deformity, and developmental dislocation or dysplasia of the hip, an occult disorder. The identification of the obvious disease, torticollis, may prompt a search for the occult dise...
1
Latarjet, Bristow, and Eden-Hybinette procedures for anterior shoulder dislocation: systematic review and quantitative synthesis of the literature
Glenohumeral Joint OA
PURPOSE: The aim of this study was to evaluate clinical outcome, rate of recurrence, complications, and rate of postoperative osteoarthritis in patients with anterior shoulder instability managed with Latarjet, Bristow, or Eden-Hybinette procedures. METHODS: A systematic review of the literature on management of anteri...
1
Epidemiological burden of postmenopausal osteoporosis in Italy from 2010 to 2020: estimations from a disease model
HipFx Supplemental Cost Analysis
The article describes the adaptation of a model to estimate the burden of postmenopausal osteoporosis in women aged 50 years and over in Italy between 2010 and 2020. For this purpose, a validated postmenopausal osteoporosis disease model developed for Sweden was adapted to Italy. For each year of the study, the 'incide...
0
The effect of endoskeleton on antibiotic impregnated cement spacer for treating deep hip infection
DoD SSI (Surgical Site Infections)
BACKGROUNDS: A two-stage revision arthroplasty was suggested optimal treatment for deep infections in hip joint. The effect of endoskeleton of cement spacers on the interim function and infection control remains unclear. METHODS: From Jan. 2004 to Dec. 2007, we collected a prospective cohort of consecutive 34 patients ...
0
Total knee arthroplasty fixation. Comparison of the early results of paired cemented versus uncemented porous coated anatomic knee prostheses
Surgical Management of Osteoarthritis of the Knee CPG
The results of 18 matched pairs of Porous Coated Anatomic knee prostheses were studied to compare the early clinical and functional performance of cemented versus uncemented fixation with an average five-year follow-up period for both. The knee score improved from a preoperative average of 35 points to a postoperative ...
0
A classification and grading system for Barton fractures
Distal Radius Fractures
PURPOSE: We described a morphological classification and grading system for volar Barton fractures. METHODS: We divided these fractures into four types: typical Barton, ulna Barton, radial Barton, comminuted Barton. Moreover, we graded the fractures into two degrees: simple split and split-depression. We retrospectivel...
0
Long-term outcome and risk factors of proximal femoral fracture in uncemented and cemented total hip arthroplasty in 2551 hips
Management of Hip Fractures in the Elderly
Proximal femoral fractures are relatively common during total hip arthroplasty. The purposes of this study were to identify risk factors associated with femoral fractures and determine their effect on femoral stem survivorship. A total of 2551 hips were examined with up to 16 years of follow-up (mean, 6.8 years). Seven...
1
Femoral nerve block for patient undergoing total knee arthroplasty: Prospective, randomized, double-blinded study evaluating analgesic effect of perineural fentanyl additive to local anesthetics
AAHKS (9/10) Regional Nerve Blocks
BACKGROUND: The existence of peripheral opioid receptors and its effectiveness in peripheral nerve block remain controversial. The aim of this prospective, randomized, double-blinded study was to examine the analgesic effects of adding fentanyl to ropivacaine for continuous femoral nerve block (CFNB) using patient-cont...
0
Retrospective, multicenter, observational study of 112 surgically treated cases of humerus metastasis
Pediatric Supracondylar Humerus Fracture 2020 Review
INTRODUCTION: The humerus is the second most common site for metastasis in the peripheral skeleton. These humeral metastases (HM) occur in the midshaft in 42% to 61% of cases and theproximal humerus in 32% to 45% of cases. They are often secondary to primary breast (17-31%), kidney (13-15%) or lung (11-24%) cancer. The...
0
PR11-364P22.2/ATF3 protein interaction mediates IL-1beta-induced catabolic effects in cartilage tissue and chondrocytes
AMP (Acute Meniscal Pathology)
Osteoarthritis (OA) is a degenerative joint disease which lacks effective medical treatment due to ill-defined molecular mechanisms underlying the pathology. Inflammation is a key factor that induces and aggravates OA. Therefore, the current study aims to explore roles of the dysregulated long non-coding RNAs in the pr...
0
MRI of the wrist
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
In the past, the diagnostic imaging algorithm for evaluating the painful wrist included initial plain radiographic examination followed by arthrography, tomography, bone scintigraphy, or computed tomography. In recent years, magnetic resonance imaging (MRI) has been proven efficacious for diagnosing a number of maladie...
0
Early postoperative cartilage evaluation by magnetic resonance imaging using T2 mapping after arthroscopic partial medial meniscectomy
AMP (Acute Meniscal Pathology)
PURPOSE: This study was performed to quantitatively evaluate postoperative changes in cartilage by T2 mapping after arthroscopic partial medial meniscectomy. MATERIAL AND METHODS: The study enrolled 17 patients with 20 knees that underwent arthroscopic partial medial meniscectomy. MRI was performed preoperatively and a...
0
The suspension (Frost) suture: experience and applications
Upper Eyelid and Brow Surgery
BACKGROUND: The Frost suture is a well-known surgical technique for providing upward tension on the lower lid to prevent or correct ectropion after surgical interventions in the periorbital area. Despite its relatively common use, comprehensive information on executing this technique is not readily available. OBJECTIVE...
0
Corrective osteotomy through fracture site and internal fixation with headless screws for type I (Hahn-Steinthal) capitellar malunion
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
A 20-year-old woman presented 6 months after an initial injury to her left elbow with pain and restricted movements. She was diagnosed with a type I malunited (Hahn-Steinthal) type of capitellum fracture through radiographic studies. Classically, the treatment has been excision of the fragment, which carries a risk of ...
0
Automatic identification algorithm of meniscus tear based on radiomics of knee MRI
AMP (Acute Meniscal Pathology)
OBJECTIVE: To establish a classification model based on knee MRI radiomics, realize automatic identification of meniscus tear, and provide reference for accurate diagnosis of meniscus injury. METHODS: A total of 228 patients (246 knees) with meniscus injury who were admitted between July 2018 and March 2021 were select...
0
High survival of dome pelvic osteotomy in patients with early osteoarthritis from hip dysplasia hip
PJI DX Updated Search
Background: The Chiari osteotomy reportedly has a 60% to 91% survival rate at a minimum 20 years followup. The dome pelvic osteotomy (DPO) has the advantage of allowing a larger weightbearing surface, and congruity in the sagittal plane presumably would reduce the joint contact stress and perhaps increase longevity. Qu...
0
A morphological study on femoral heads in human hip joint osteoarthrosis
Management of Hip Fractures in the Elderly
Several pathogenetical and clinical interpretation of osteoarthritic modifications are given in the literature. In this work we tried to compare in humans macroscopic, structural and ultrastructural observations on eight osteoarthritic with four femural heads from control patients. The sample for Light Microscopy and S...
0
Cleidocranial Dysplasia Spectrum Disorder GeneReviews R
Dental Implant Infection
CLINICAL CHARACTERISTICS: Cleidocranial dysplasia (CCD) spectrum disorder is a skeletal dysplasia that represents a clinical continuum ranging from classic CCD (triad of delayed closure of the cranial sutures, hypoplastic or aplastic clavicles, and dental abnormalities), to mild CCD, to isolated dental anomalies withou...
0
Faster recovery without the use of a tourniquet in total knee arthroplasty
AAHKS (4) Acetaminophen
Background and purpose - Tourniquet application is still a common practice in total knee arthroplasty (TKA) surgery despite being associated with several adverse effects. We evaluated the effects of tourniquet use on functional and clinical outcome and on knee range of motion (ROM). Patients and methods - 70 patients w...
0
The early results of metal-on-metal hip resurfacing: A prospective study at a minimum two-year follow-up
Management of Hip Fractures in the Elderly
Hip resurfacing has recently been offered as an attractive alternative to conventional total hip arthroplasty. This report evaluated the short-term functional outcome and longevity of a newer generation resurfacing device and includes the results of 228 consecutive hip resurfacings in 209 patients at a minimum of two-y...
1
A prospective investigation of long-term cognitive impairment and psychological distress in moderately versus severely injured trauma intensive care unit survivors without intracranial hemorrhage
DoD PRF (Psychosocial RF)
BACKGROUND: The primary objective was to prospectively determine the 12-month prevalence of cognitive impairment and psychologic difficulties in moderately versus severely injured adult trauma intensive care unit (TICU) survivors without intracranial hemorrhage. METHODS: We conducted a prospective cohort study in which...
0
Pain intensity and Patients' acceptance of surgical complication risks with lumbar fusion
DoD SSI (Surgical Site Infections)
STUDY DESIGN.: Cross-sectional study with prospective recruitment. OBJECTIVE.: To determine the relationship of pain intensity (back and leg) on patients' acceptance of surgical complication risks when deciding whether or not to undergo lumbar spinal fusion. SUMMARY OF BACKGROUND DATA.: To formulate informed decisions ...
0
Salter-Harris I fractures of the distal radius misdiagnosed as wrist sprain
Distal Radius Fractures
Over a period of 5 years, 65 children under 12 years of age were diagnosed as having 'wrist sprain' at the American University of Beirut Medical Center, Emergency Department. Thirty-eight children were reevaluated; 33 patients (86.8%) were diagnosed as having a Salter-Harris I fracture of the distal radius that necessi...
0
Ewing's sarcoma: Experience with 12 cases
MSTS 2018 - Femur Mets and MM
Twelve patients with localized Ewing's sarcoma were treated between 1980-1990 at the Istanbul School of Medicine, Department of Pediatric Oncology-Hematology, Oncology Research and Treatment Center and Our Children Leukemia Foundation. There were 8 boys and 4 girls, with a mean age of 8.1 (range 3-17) years. The tumors...
0
Review of Spinal cord injury in the child and young adult
DoD PRF (Psychosocial RF)
Reviews the book, Spinal Cord Injury in the Child and Young Adult edited by L. C. Vogel, K. Zebracki, R. R. Betz and M. J. Mulcahey (2014). The current volume is an expansion of the first published work The Child With a Spinal Cord Injury (American Academy of Orthopedic Surgeons, Rosemont, IL, 1996). The focus of the b...
0
Revision Total Hip Arthroplasty after Ceramic Bearing Fractures in Patients Under 60-years Old; Mid-term Results
Hip Fx in the Elderly 2019
Purpose: Although advances in technology have reduced the risk of ceramic implant fractures in total hip arthroplasty, these injuries do occur and their treatment remains challenging. There is a lack of studies reporting on the effectiveness of ceramic components in revision hip arthroplasty after ceramic bearing fract...
0
Osteoarthritis of the wrist following Colles' fracture: A primary or secondary phenomenon?
Distal Radius Fractures
Both wrists and hands of 51 patients, who had sustained unilateral Colles' fracture 10 years previously, were examined radiologically for osteoarthritis (OA). Twenty-nine demonstrated OA, which in only five was confined to the injured wrist. The prevalence of OA was comparable in both injured and uninjured wrists. Radi...
1
Factors associated with long-term functional and psychological outcomes in persons with moderate to severe traumatic brain injury
DoD PRF (Psychosocial RF)
OBJECTIVE: To examine factors impacting long-term functional and psychological outcomes in persons with moderate-severe traumatic brain injury. METHODS: A prospective cross-sectional study (n=103) assessed the long-term (up to 5 years) impact of traumatic brain injury on participants' current activity and restriction i...
1
Deep vein harvest: predicting need for fasciotomy
DOD - Acute Comp Syndrome CPG
OBJECTIVE: Deep thigh veins, including the superficial femoral, superficial femoropopliteal, and profunda femoris veins, are versatile autogenous conduits for arterial reconstruction. Although late venous complications are unusual, deep vein harvest may induce severe venous hypertension and predispose the limb to acute...
0
Osteonecrosis of the myeloma patients treated with bisphosphonates
MSTS 2018 - Femur Mets and MM
Osteonecrosis of the jaw (ONJ) has been reported as uncommon but well recognised complication associated with bisphosphonate treatment. Multiple Myeloma (MM) is the pathology most frequently associated with ONJ in the medical and dental papers published over the last years (45% of the ONJ published cases). ONJ appears ...
0
Isolated limb infusion with melphalan and dactinomycin for regional melanoma and soft-tissue sarcoma of the extremity: Final report of a phase II clinical trial
DOD - Acute Comp Syndrome CPG
Isolated limb infusion (ILI) is a minimally invasive technique of delivering regional chemotherapy in patients with advanced melanoma or soft-tissue sarcoma of the limb. We report the final results of the first clinical trial of ILI in North America (NCT00004250). Eligible patients had recurrent melanoma or unresectabl...
0
Audit-induced change reduces complications of the Ganz trochanteric flip approach
Management of Hip Fractures in the Elderly
INTRODUCTION: The Ganz trochanteric flip approach aims to avoid the potential risk of avascular necrosis in hip conserving surgery and may reduce the risk of femoral neck fractures, neck thinning and femoral head implant migration in hip resurfacing. Our initial audit revealed the complications of non-union and trochan...
0
Impact of Juvenile Idiopathic Arthritis Associated Uveitis in Early Adulthood
Upper Eyelid and Brow Surgery
BACKGROUND: Typically juvenile idiopathic arthritis (JIA)-associated uveitis (further referred as 'JIA-uveitis') has its onset in childhood, but some patients suffer its, sometimes visual threatening, complications or ongoing disease activity in adulthood. The objective of this study was to analyze uveitis activity, co...
0
Impact of a Postoperative Intervention Educational Program on the Quality of Life of Patients with Hip Fracture: A Randomized, Open-Label Controlled Trial
Hip Fx in the Elderly 2019
The objective of this study was to determine the impact of a postoperative educational intervention program on the health-related quality of life (HRQoL) of patients with hip fracture using a controlled clinical trial in a randomized, multicenter study. In total, 102 patients (45.5%) from trauma units at the two Univer...
0
Choice of surgical approach for capitellar fractures based on pathoanatomy of fractures: outcomes of surgical management
Pediatric Supracondylar Humerus Fracture 2020 Review
The understanding of the anatomic configuration of the fractures of the capitellum has enhanced in the last few years, and the classification of these fractures continues to evolve. It is essential to tailor the surgical approaches to these fractures based on the state-of-the-art classifications. Thirty-three patients ...
0
Postoperative pain after hip fracture is procedure specific
AAHKS (8) Anesthetic Infiltration
Background. Hip fracture patients experience high pain levels during postoperative rehabilitation. The role of surgical technique on postoperative pain has not been evaluated previously. Methods. One hundred and seventeen hip fracture patients were included in a descriptive prospective study. All patients received cont...
0
Bactericidal micron-thin sol-gel films prevent pin tract and periprosthetic infection
PJI DX Updated Search
Orthopedic injuries constitute the majority of wounds sustained by U.S. soldiers in recent conflicts. The risk of infection is considerable with fracture fixation devices. In this pilot study, we examined the use of unique bactericidal micron-thin sol-gel films on fracture fixation devices and their ability to prevent ...
0
Advances in segmental endoprosthetic reconstruction for extremity tumors: a review of contemporary designs and techniques
PJI DX Updated Search
BACKGROUND: Improved understanding and advances in treatment regimens have led to increased longevity among patients diagnosed with extremity soft tissue sarcomas. Limb salvage techniques and implants have improved and continue to evolve to accommodate the increasing demands and survival of these patients. METHODS: The...
0
Alendronate in the treatment of primary hyperparathyroid-related osteoporosis: A 2-year study
Management of Hip Fractures in the Elderly
We investigated the effect of alendronate on calcium, PTH, and bone mineral density in 27 female and 5 male patients with primary hyperparathyroidism. The treatment group [n = 14; T score (less-than or equal to) -2.5 SD at the femoral neck (FN) or T (less-than or equal to) -1.0 SD plus previous nonvertebral fracture] w...
1
Prognostic Factors for the Clinical Outcome after Microfracture Treatment of Chondral and Osteochondral Defects in the Knee Joint: A Systematic Review
Osteochondritis Dissecans 2020 Review
OBJECTIVE: The objective of this study is to establish which patient and lesion characteristics are related to the clinical outcome after microfracture of cartilage defects in the knee. STUDY DESIGN: Systematic review. METHODS: After preregistration, PubMed, Embase, and Cochrane were searched for studies that analyzed ...
0
Cost effectiveness of denosumab compared with oral bisphosphonates in the treatment of post-menopausal osteoporotic women in Belgium
HipFx Supplemental Cost Analysis
Background: Denosumab has recently been shown to be well tolerated, to increase bone mineral density (BMD) and to significantly reduce the risk of hip, vertebral and non-vertebral fractures in the FREEDOM (Fracture REduction Evaluation of Denosumab in Osteoporosis every 6 Months) trial. It is becoming increasingly impo...
1
Assessing late-onset stress symptomatology among aging male combat veterans
DoD PRF (Psychosocial RF)
This study's goal was to develop a measure of late-onset stress symptomatology (LOSS). LOSS is a phenomenon observed in aging combat veterans who (a) were exposed to highly stressful combat events in their early adult years, (b) have functioned successfully throughout midlife with no history of chronic stress-related d...
0
Workplace managersâ?? view of the role of co-workers in return-to-work
DoD PRF (Psychosocial RF)
Purpose: Theoretical and empirical research findings attest to the workplace being a social environment in which co-workers have a critical influence on the employment outcomes and return-to-work (RTW) success of other employees. However, co-workers do not have a formal role in RTW planning. The aim of this study was t...
0
An evaluation of the cutaneous distribution after obturator nerve block
AAHKS (9/10) Regional Nerve Blocks
UNLABELLED: In 1973, Winnie et al. introduced the inguinal paravascular three-in-one block, which allegedly provides anesthesia of three nerves--the femoral, lateral cutaneous femoral, and obturator nerves--with a single injection. This concept was undisputed until the success of the obturator nerve block was reassesse...
0
Osteonecrosis of the knee: review
Osteochondritis Dissecans 2020 Review
Osteonecrosis is a devastating disease that can lead to end-stage arthritis of various joint including the knee. There are three categories of osteonecrosis that affect the knee: spontaneous osteonecrosis of the knee (SONK), secondary, and post-arthroscopic. Regardless of osteonecrosis categories, the treatment of this...
0
Demystifying medical complexities
Dental Implant Infection
Although dentists often fear treating medically complex patients, in many cases this fear may be based not on scientific facts but rather on a "mythology" of the dangers of dentistry. Dentistry is a remarkably safe profession, even for most medically complex patients. The myths of endocarditis, artificial joint infecti...
0
A universal snap-fit endoprosthesis for the treatment of subcapital fractures of the femur: a preliminary report
Management of Hip Fractures in the Elderly
A new endoprosthesis for the treatment of subcapital fractures is described. It is hemispherical with a high density polyethylene (HDP) core which is snap-fitted onto a Charnley-type femoral prosthesis. The aim is to prevent acetabular erosion by its virtual lack of movement of the cartilage-metal interface. If this sh...
0
Managing the medically compromised geriatric patient
Dental Implant Infection
Demographic trends indicate that dentists will be treating more dentate geriatric patients, many of whom will be medically compromised. This article emphasizes the effect advancing age may have on the identification and management of common medical problems. In particular, cardiovascular disease, (ischemic heart diseas...
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Detection of malignant soft tissue tumors in bone imaging
MSTS 2018 - Femur Mets and MM
A total of 2530 consecutive bone scans were examined to evaluate the number and the type of soft tissue neoplasms detected with bone-seeking phosphonates. Sixty-eight primary or secondary soft tissue neoplasms of 63 patients accumulated 99mTc -methylene diphosphonate and 2 accumulated 99mTc -diphosphonate, and one meta...
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Bisphosphonate therapy for skeletal malignancies and metastases: impact on jaw bones and prosthodontic concerns
MSTS 2018 - Femur Mets and MM
Healthy jawbones ensure better tooth anchorage and the ability to masticate and maintain metabolism. This is achieved by a delicate balance between bone formation and resorption in response to functional demands. An imbalance in the expression of receptor activator of nuclear factor kappa-B (RANK) ligand (RANKL) and os...
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Associations of parity, breast-feeding, and birth control pills with lumbar spine and femoral neck bone densities
Management of Hip Fractures in the Elderly
The relationships between parity, breast-feeding, and the use of birth control pills and the bone densities of the lumbar spine and the femoral neck, measured by dual-photon densitometry, were studied in normal women. Femoral neck density was found to decrease by 1.1% per live-birth, whereas lumbar spine density showed...
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Effects of Liposomal Bupivacaine With Adductor Canal Block on Pain and Functional Outcomes in Patients Undergoing Total Knee Arthroplasty
AAHKS (8) Anesthetic Infiltration
BACKGROUND: Liposomal bupivacaine (LB) has an extended duration of action compared to bupivacaine and may allow patients to reach physical therapy (PT) goals faster than traditional methods. OBJECTIVE: To determine the effect of a periarticular LB mixture with adductor canal blockade (ACB) on postoperative opioid requi...
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Childhood adversity, social support, and telomere length among perinatal women
DoD PRF (Psychosocial RF)
Adverse perinatal health outcomes are heightened among women with psychosocial risk factors, including childhood adversity and a lack of social support. Biological aging could be one pathway by which such outcomes occur. However, data examining links between psychosocial factors and indicators of biological aging among...
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Cardiovascular disease predicts complications following bilateral total knee arthroplasty under a single anesthetic
Surgical Management of Osteoarthritis of the Knee CPG
INTRODUCTION: This study evaluated the rate of perioperative complications of single anesthetic bilateral total knee arthroplasties (TKA) compared with staged procedures. METHODS: The records of all single anesthetic bilateral TKA performed between 1997 and 2007 at one large community hospital and one university hospit...
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Spectrum of common and uncommon causes of knee joint hyaline cartilage degeneration and their key imaging features
Osteochondritis Dissecans 2020 Review
Hyaline cartilage lining the surfaces of diarthrodial joints is an important construct for transmission of load and to reduce friction between the bones. Normal wear and tear accounts for about 3–5 percent knee cartilage loss ever year in otherwise healthy people after the age of 30 years. Several conditions and diseas...
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The operative management of displaced intra-articular fractures of the calcaneum: a two-centre study using a defined protocol
DoD SSI (Surgical Site Infections)
The management of intra-articular calcaneal fractures remains controversial with strong arguments supporting both conservative and operative management. This study assesses the results of open reduction and internal fixation (ORIF) of displaced intra-articular fractures of the calcaneum in two independent centres where...
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Speckle tracking ultrasound for assessment of the relative motion of flexor tendon and subsynovial connective tissue in the human carpal tunnel
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
The objective of this study was to compare tissue Doppler imaging and speckle tracking ultrasound to assess the relative motion of flexor tendon and surrounding subsynovial connective tissue (SSCT). Twenty normal human wrists were imaged with an ultrasound scanner. The two ultrasound methods measured the excursion and ...
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Employment outcome four years after a severe traumatic brain injury: results of the Paris severe traumatic brain injury study
DoD PRF (Psychosocial RF)
OBJECTIVE: To describe employment outcome four years after a severe traumatic brain injury by the assessment of individual patients' preinjury sociodemographic data, injury-related and postinjury factors. DESIGN: A prospective, multicenter inception cohort of 133 adult patients in the Paris area (France) who had receiv...
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Total Knee Arthroplasty in Patients With Juvenile Idiopathic Arthritis
Surgical Management of Osteoarthritis of the Knee CPG
BACKGROUND: Total knee arthroplasty (TKA) for juvenile idiopathic arthritis is rare but is nonetheless indicated for many patients with this disease. Few reports exist on the results of TKA in patients with juvenile idiopathic arthritis. QUESTIONS/PURPOSES: It was sought to determine (1) survivorship and (2) functional...
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Steep posterior slope of the medial tibial plateau and anterior cruciate ligament degeneration contribute to medial meniscus posterior root tears in young patients
AMP (Acute Meniscal Pathology)
PURPOSE: Medial meniscus posterior root tears (MMPRTs) occur most frequently in middle-aged and older adults. However, this serious condition can also occur in younger patients. The purpose of this study was to compare anterior cruciate ligament (ACL) degeneration and sagittal medial tibial slope in young adults with a...
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Hemiarthroplasty or total hip arthroplasty for the treatment of a displaced intracapsular fracture in active elderly patients: 12-year follow-up of randomised trial
Hip Fx in the Elderly 2019
AIMS: Our aim was to analyse the long-term functional outcome of two forms of surgical treatment for active patients aged > 70 years with a displaced intracapsular fracture of the femoral neck. Patients were randomised to be treated with either a hemiarthroplasty or a total hip arthroplasty (THA). The outcome five year...
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Microscopic and Macroscopic Fat Embolism: Solving the Puzzle with Case Reports
Panniculectomy & Abdominoplasty CPG
BACKGROUND: The frequency of fat embolism mortality after liposuction has increased. As the only dependable evidence for this problem is that available in the medical literature, a study of clinical case reports is warranted. METHODS: The authors reviewed the medical literature by searching for case reports of fat embo...
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Comparison of MRI- and CT-based patient-specific guides for total knee arthroplasty
Surgical Management of Osteoarthritis of the Knee CPG
BACKGROUND: The patient-specific guide for total knee arthroplasty (TKA) is created from the data provided by magnetic resonance imaging (MRI) or computed tomography (CT) scans. It remains unknown which imaging technology is suitable for the patient-specific guide. The purpose of this study was to compare the accuracy ...
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Antiepileptic drug use increases rates of bone loss in older women: a prospective study
Management of Hip Fractures in the Elderly
OBJECTIVE: To test the hypothesis that older women with antiepileptic drug (AED) use have increased rates of bone loss. METHODS: AED use was ascertained and calcaneal and hip bone mineral density (BMD) measured in a cohort of 9,704 elderly community-dwelling women enrolled in the Study of Osteoporotic Fractures, and th...
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Prognostic factors affecting anatomic outcome of rotator cuff repair and correlation with functional outcome
Optimizing the Management of Full-Thickness Rotator Cuff Tears
PURPOSE: To analyze the relationship between functional outcomes and postoperative cuff integrity (anatomic outcome), and to reveal the factors affecting outcomes of rotator cuff repair. METHODS: Seventy-eight patients who had undergone repair of full-thickness rotator cuff tear received both computed tomographic arthr...
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Aspiration lipectomy and adipose tissue injection: Pathophysiologic commentary
Panniculectomy & Abdominoplasty CPG
The subcutis, made up of connective and adipose tissue, may consist of one or two layers, depending on the part of the body. The superficial layer, up to 10 mm in thickness, has the function of giving contour. In localizations where one typically sees relatively large fat deposits a padding layer is added to the contou...
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Soft-tissue reconstruction in orthopedic surgery. Secondary procedures
Panniculectomy & Abdominoplasty CPG
The original consulting microsurgeon should be present to assist in the identification and protection of the vascular pedicle during secondary procedures on microvascular transplants. Flap elevation, trimming, and bone graft placement should be completed during a single tourniquet time, whenever possible. Flaps can eas...
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The advantages of carbon fiber based orthopedic devices in patients who have to undergo radiotherapy
MSTS 2022 - Metastatic Disease of the Humerus
BACKGROUND AND OBJECTIVES: The modern approach to primary and secondary muscular skeletal tumors is multidisciplinary. The right combination of chemotherapy, surgery and radiotherapy (RT) makes obtaining local and distant disease control more likely. When surgery is indicated, radiotherapy often has a fundamental role ...