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Antibiotic use before chemotherapy: a risk factor for developing neutropenic colitis in children with leukemia
Patrick’s pharmacoepidemiology project
BACKGROUND: It has been shown that the use of antimicrobials is a determinant that favors intestinal dysbiosis. The objective of this study is to establish the association between the previous use of antimicrobials and the development of neutropenic colitis (NC). METHODS: A case-control study was carried out with subje...
0
Novel approaches to the management of myeloma
MSTS 2018 - Femur Mets and MM
Standard therapy for multiple myeloma, which accounts for 10% of all hematologic malignancies, has been autologous stem cell transplantation (ASCT), alkylator-based chemotherapy, and corticosteroids. Several advances have been made in the treatment of multiple myeloma over the past decade, especially the arrival of new...
0
Inhibition of Nrf2/HO-1 signaling leads to increased activation of the NLRP3 inflammasome in osteoarthritis
AMP (Acute Meniscal Pathology)
INTRODUCTION: Osteoarthritis (OA) is an inflammatory disease of the joints that causes progressive disability in the elderly. Reactive oxygen species (ROS) play an important role in OA development; they may activate the NLRP3 inflammasome, thereby inducing the secretion of proinflammatory IL-1beta and IL-18, leading to...
0
Location of metastatic breast carcinoma by a monoclonal antibody chelate labelled with indium-111
MSTS 2018 - Femur Mets and MM
The ability of a radiolabelled monoclonal antibody, LICR-LON-M8 (M8), to locate metastatic breast carcinomas has been investigated. The scans generated by M8, either when labelled with radioiodine, or when conjugated with diethylenetriamine-pentaacetic acid (DTPA) and labelled with radioactive indium (111In), have been...
0
Brake response time before and after total knee arthroplasty: a prospective cohort study
Surgical Management of Osteoarthritis of the Knee CPG
BACKGROUND: Although the numbers of total knee arthroplasty (TKA) are increasing, there is only a small number of studies investigating driving safety after TKA. The parameter 'Brake Response Time (BRT)' is one of the most important criteria for driving safety and was therefore chosen for investigation.The present stud...
0
Influence of medial and lateral hamstring strengthening exercises in women with osteoarthritis knee: A randomized trail
OAK 3 - Non-arthroplasty tx of OAK
OA is a progressive degenerative disease that affects the joint cartilage, subchondral bone, and the synovial joint capsule. It has a multifactorial etiology and affects approximately 60% of individuals older than 50 years of age2. The knee is the most common weight-bearing joint affected by OA with the disease predomi...
0
Reduced hospital stay and narcotic consumption, and improved mobilization with local and intraarticular infiltration after hip arthroplasty: a randomized clinical trial of an intraarticular technique versus epidural infusion in 80 patients
AAHKS (4) Acetaminophen
BACKGROUND: Epidural analgesia gives excellent pain relief but is associated with substantial side effects. We compared wound infiltration combined with intraarticular injection of local anesthetics for pain relief after total hip arthroplasty (THA) with the well-established practice of epidural infusion. METHODS: 80 p...
0
Progressive hemiosteoporosis on the paretic side and increased bone mineral density in the nonparetic arm the first year after severe stroke
Management of Hip Fractures in the Elderly
Fractures are a common and serious complication after stroke and the risk of hip fractures among stroke patients is 2 to 4 times greater than among other elderly people. The aim of this study was to investigate prospectively the change in bone mineral density (BMD) after severe stroke and to study the association betwe...
1
Platelet-Rich Plasma for Sport-Active Patients with Knee Osteoarthritis: Limited Return to Sport
PRP (Platelet-Rich Plasma)
Objective: To evaluate a cohort of sport-active patients suffering from cartilage degeneration and OA, in terms of clinical outcome and return to sport (RTS) after platelet-rich plasma (PRP) injective treatment. Design: This study included forty-seven sport-active patients <=50 years old with unilateral symptomatic kne...
0
Bilateral axillary masses mimicking as accessory breast with multiple fibroadenoma and bilateral gigantomastia in HIV-positive patient
Reduction Mammoplasty for Female Breast Hypertrophy
Accessory breast is a rare entity that can present as asymptomatic masses or can cause symptoms like heaviness, pain, restriction of arm movement and limitation in daily pursuits with allied apprehension and anxiety for the patient. We present a case of bilateral axillary masses mimicking as accessory breast with multi...
0
Indoor wayfinding: developing a functional interface for individuals with cognitive impairments
Upper Eyelid and Brow Surgery
PURPOSE: Assistive technology for wayfinding will significantly improve the quality of life for many individuals with cognitive impairments. The user interface of such a system is as crucial as the underlying implementation and localisation technology. We studied the user interface of an indoor navigation system for in...
0
Tibial plateau fractures: four years review at B & B Hospital
DoD SSI (Surgical Site Infections)
BACKGROUND: Tibial plateau fractures involve the articular surface of the tibia resulting from a combination of axial loading with varus or valgus stress. Inadequate and inappropriate treatment may result in significant functional loss. OBJECTIVE: The purpose of this study was to determine the outcome of our treatment ...
0
Correlationship of Cathepsin D and Topoisomerase Ii Alpha with Nuclear Grading in Breast Cancers
MSTS 2018 - Femur Mets and MM
56 cases of infiltrating duct carcinoma of the breast were studied for the expression of cathepsin D and topoisomerase II alpha. The results were correlated with the morphological differentiation, as determined by the Nottingham's modification of the Bloom-Richardson system. Cathepsin D posltivity in tumour cells and s...
0
Treatment of lower extremity long bone nonunion with expandable intramedullary nailing and autologous bone grafting
DoD SSI (Surgical Site Infections)
BACKGROUND: Nonunion of long bones in lower limbs is a common complication of orthopedic trauma that can be extremely debilitating. This retrospective study describes our experience using expandable intramedullary nails and autologous bone grafting in treating lower limb long bone nonunion with bone defects. METHODS: N...
0
YM-150, a Factor Xa inhibitor for the prevention of venous thromboembolism and coronary artery disease
PJI DX Updated Search
The oral Factor Xa inhibitor YM-150 is being developed by Astellas Pharma Inc for the prevention of venous thromboembolism (VTE) in patients undergoing surgery and for coronary artery disease. In preclinical thrombosis models, as well as in phase II clinical trials in patients undergoing primary hip replacement surgery...
0
Anatomic tumor location influences the success of contemporary limb-sparing surgery and radiation among adults with soft tissue sarcomas of the extremities
DoD LSA (Limb Salvage vs Amputation)
Purpose: To examine the influence of anatomic location in the upper extremity (UE) vs. lower extremity (LE) on the presentation and outcomes of adult soft tissue sarcomas (STS). Methods and Materials: From 2001 to 2008, 118 patients underwent limb-sparing surgery (LSS) and external beam radiotherapy (RT) with curative ...
0
Current concepts in diagnosis and management of periprosthetic infection
PJI DX Updated Search
Infection remains a devastating complication of total joint arthroplasty. There have been many significant advances to help identify and reduce the risks of infection over the years. However, when an infection occurs, the management can be complex. This article reviews some of the basic treatment strategies for infecte...
0
MRI of the medial meniscus in patients over 40 years of age with osteoarthritic knees
AMP (Acute Meniscal Pathology)
MRI was performed for 171 medial menisci of 147 patients, ranging in age from 40 to 86 years (mean 66.6 years), who showed clinical signs in the medial compartment. We classified the MRI findings of the medial menisci using the modified grading system of Crues et al. (Radiology 1987;164:445- 448) [1], and their grade 3...
0
Long-term survivorship of a monoblock long cementless stem in revision total hip arthroplasty
Hip Fx in the Elderly 2019
PURPOSE: The purpose of this study was to assess the clinical outcomes, complications, and survival of a long cementless titanium femoral stem in revision total hip arthroplasty (THA) at a minimum five year follow-up. METHODS: Between 2000 and 2010, 114 patients (116 hips), with a mean age of 68 +/- 12 years, underwent...
0
Prevalence of Fracture Risk Factors in Postmenopausal Women Enrolled in the POSSIBLE US Treatment Cohort
Hip Fx in the Elderly 2019
Subject- and physician-reported data from 4,429 postmenopausal women receiving osteoporosis treatment in the Prospective Observational Scientific Study Investigating Bone Loss Experience (POSSIBLE US) were used to assess the prevalence of risk factors (RFs) and on-study fracture. RFs assessed at study entry were age >7...
0
Patellofemoral Instability: Evaluation by Magnetic Resonance Imaging
AMP (Acute Meniscal Pathology)
OBJECTIVE: To determine the contribution of magnetic resonance imaging (MRI) in evaluating patelofemoral instability. METHODS: 39 patients (45 knees) with patellar instability underwent knee magnetic resonance images between October 2009 and July 2011, at the Rede Lab's D'Or, in the city of Rio de Janeiro, State of Rio...
0
Primary Candida guilliermondii Infection of the Knee in a Patient without Predisposing Factors
Surgical Management of Osteoarthritis of the Knee CPG
Isolated primary candidal infection of joint is extremely rare, with only a few reported cases. It occurs as a result of accidental implantations of fungus during traumatic procedures, such as surgery, and is usually reported in patients with predisposing factors such as immunosuppression, malignancy, and drug abuse. I...
0
Treatment With Helical Blade Cephalomedullary Nail for Two-Part Basicervical Proximal Femoral Fracture in Elderly Patients: A Retrospective Observational Study
Hip Fx in the Elderly 2019
Background: Basicervical proximal femoral fracture is a known subtype of extracapsular fracture and is mechanically unstable, especially for the rotational direction, which may lead to implant failure. A cephalomedullary nail (CMN) is widely used for the fixation of unstable extracapsular fracture; however, its applica...
0
Perineal hygiene in patients with pelvic fractures
DoD SSI (Surgical Site Infections)
At the tertiary referral Orthopaedic Unit of St. Georges Hospital, it was noted that there was an unacceptably high number of soiled perinea in patients transferred from Base Hospitals. This not only exposed the patients to increased infection [Jepsen O. The effectiveness of preoperative skin preparations: an integrate...
1
Pre-operative analgesia for patients with femoral neck fractures using a modified fascia iliaca block technique
Management of Hip Fractures in the Elderly
Adequate pre-operative analgesia for elderly patients with femoral neck fractures is difficult to assess and is often an overseen aspect of their care. We aimed to assess the efficacy of fascia iliaca blocks inserted via plexus blockade catheters in the pre-operative period. Our simple technique allowed the block to be...
0
Elective Tracheostomy During Mechanical Ventilation in Patients Affected by COVID-19: Preliminary Case Series From Lombardy, Italy
Coronavirus Disease 2019 (COVID-19)
The COVID-19 outbreak poses continued struggles due to the unprecedented number of patients admitted to intensive care units and the overwhelming need for mechanical ventilation. We report a preliminary case series of 32 patients with COVID-19 who underwent elective tracheostomies after a mean intubation period of 15 d...
0
Safety of total hip replacement following an intra-articular steroid hip injection--an audit
PJI DX Updated Search
The aim of this study was to determine the deep infection rates in patients who underwent a total hip replacement after having had a prior diagnostic steroid injection into the same hip. We identified and reviewed the case notes, relevant radiographs and microbiology reports of all patients who underwent a total hip re...
0
Prevalence of vertebral fractures in French women older than 75 years from the EPIDOS study
Management of Hip Fractures in the Elderly
The aim of this study was to ascertain the prevalence and severity of vertebral fractures in French elderly women. We used spinal radiographs collected during the baseline examination of the Epidemiologie de l'Osteoporose (EPIDOS) study, a multicentric prospective study of risk factors for hip fracture. A total of 7598...
0
Study to Evaluate The Analgesic Efficacy and Safety of Intravenous Paracetamol in Subjects With Postoperative Pain After Total Hip Arthroplasty
AAHKS (4) Acetaminophen
The main purpose is to evaluate the analgesic efficacy of 1g of intravenous (Iv) paracetamol versus i.v. placebo, administered every 6h, as measured by the reduction of the 24�hour cumulative dose of the opioid tramadol in the treatment of postoperative pain following total hip arthroplasty.
0
Open-wedge high tibial osteotomy in patients with discoid lateral meniscus
AMP (Acute Meniscal Pathology)
BACKGROUND: There are concerns about the progression of the lateral osteoarthritis (OA) should be taken into account when high tibial osteotomy (HTO) is performed in patients with discoid lateral meniscus (LM). This study evaluated the clinical results of HTO in patients with discoid LM and elucidated factors affecting...
0
The role of Sirt6 in osteoarthritis and its effect on macrophage polarization
AMP (Acute Meniscal Pathology)
Osteoarthritis (OA), the commonest arthritis type, features irreversible cartilage loss and synovitis. It was reported that macrophages have an important function in synovial inflammation, and our team revealed that the amounts of Sirt6, a nicotinamide adenine dinucleotide (NAD)<sup>+</sup>-dependent histone deacetylas...
0
One stage carotid artery resection: reconstruction in radiated head and neck carcinoma
MSTS 2018 - Femur Mets and MM
PURPOSE: Management of the carotid artery involved with metastatic squamous cell carcinoma continues to be a topic of much discussion. Early reports, for the most part, focused on the sequel of ligation and the development of various tests to predict patient tolerance for the procedure. More recent alternatives have de...
0
Meniscal Repair: a Randomized Prospective Trial of FAST-FIX vs. Meniscal Suturing
OAK 3 - Non-arthroplasty tx of OAK
In this prospective, randomized, trial subjects will be randomly assigned to the inside�out group or the FasT�Fix group and will be followed for at least 24 months. Primary outcome is the difference between groups in the disease specific quality of life assessment � The Western Ontario Meniscal Evaluation Tool. S...
0
Shared decision making in patients with osteoarthritis of the hip and knee: results of a randomized controlled trial
Surgical Management of Osteoarthritis of the Knee CPG
BACKGROUND: Despite evidence that shared decision-making tools for treatment decisions improve decision quality and patient engagement, they are not commonly employed in orthopaedic practice. The purpose of this study was to evaluate the impact of decision and communication aids on patient knowledge, efficiency of deci...
0
Salvage for intramedullary nailing breakage after operative treatment of trochanteric fractures
Hip Fx in the Elderly 2019
BACKGROUND: Trochanteric fractures are one of the most common fractures in elderly people. The use of intramedullary nails is an option for their treatment, especially in unstable patterns. Nail breakage is a rarely reported complication. The aim of this study was to determine the prevalence of nail breakage in our cen...
0
Treatment of chronic refractory osteomyelitis with adjunctive hyperbaric oxygen
DoD SSI (Surgical Site Infections)
Twenty-eight consecutive patients with chronic refractory osteomyelitis uncomplicated by persistent segmental bone defect, fracture nonunion, septic arthritis, total joint arthroplasty, or major systemic disease (immune deficiency, malignancy, diabetes mellitus, malnutrition, or renal or hepatic failure) were treated f...
0
MR imaging of lipoma arborescens and the associated lesions
AMP (Acute Meniscal Pathology)
OBJECTIVE: To describe the typical features of lipoma arborescens on MR imaging with pathologic correlation and to evaluate the associated lesions within the joints. DESIGN AND PATIENTS: The MR imaging findings of 32 patients with the diagnosis of lipoma arborescens of the knee (n=32) and shoulder (n=1) were reviewed. ...
0
The impact of a novel preventive care service on the incidence of hip fractures among the elderly
HipFx Supplemental Cost Analysis
Objective: We wanted to determine the impact of a novel preventive care service (PCS) employing home visits by non-physician experts on the incidence of hip fractures among the elderly. Methods: We estimated an ARMA model for the time series of hip fractures in the Hoganas municipality in Sweden for the years 1987-2008...
1
A method to select patients for vertical scar or inverted-T pattern breast reduction
Reduction Mammoplasty for Female Breast Hypertrophy
Vertical scar breast reduction (VSBR) is an increasingly popular technique but can carry a high complication and revision rate. We evaluate our complication rate when selecting patients for VSBR or inverted-T breast reductions (ITBR). We looked at 133 consecutive primary bilateral breast reductions performed by a singl...
0
Effect of oral clodronate on bone pain. A controlled study in patients with metastic prostatic cancer
MSTS 2018 - Femur Mets and MM
Although osteosclerotic metastases are characteristic of prostatic carcinoma, bone resorption is also accelerated. Since clodronate inhibits bone resorption and relieves bone pain, we have given it to patients with painful bone disease from prostatic cancer after failure of hormonal therapy. All patients received estra...
0
Extracorporeal photochemotherapy in the treatment of severe graft-versus-host disease
Reconstruction After Skin Cancer
Advances in posttransplant immunosuppression have to the present not been able to prevent the development of graft-versus-host disease (GVHD) in patients given related or unrelated stem cell grafts for cure of hematologic diseases. Patients with GVHD not responding to first line therapy with corticosteroids remain at h...
0
FRAX Update
Pediatric Supracondylar Humerus Fracture 2020 Review
The fracture risk assessment tool, FRAX, was released in 2008 and provides country-specific algorithms for estimating individualized 10-year probability of hip and major osteoporotic fracture (hip, clinical spine, distal forearm, and proximal humerus). Since its release, models are now available for 63 countries, cover...
0
Distal Humeral Fractures in Adults
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
Distal humeral fractures in adults often pose a challenge to the orthopaedic surgeon. Preoperative planning, minimal devitalization of bone and soft tissue, and adherence to the prerequisites of biomechanical fixation are all important elements in effecting the desired end result. The chevron modification of the olecra...
0
Glomus tumour following a total knee replacement: a case report
Surgical Management of Osteoarthritis of the Knee CPG
Pain following total knee replacement (TKR) is a common problem and cause of poor satisfaction amongst patients. We report on a glomus tumour causing pain on the anterolateral aspect of the knee, 2 years after an otherwise successful total knee replacement for osteoarthritis. The tumour was treated by excision biopsy u...
0
Early revisions of the Femoro-Patella Vialla joint replacement
Surgical Management of Osteoarthritis of the Knee CPG
The aim of this study was to review the early outcome of the Femoro-Patella Vialla (FPV) joint replacement. A total of 48 consecutive FPVs were implanted between December 2007 and June 2011. Case-note analysis was performed to evaluate the indications, operative histology, operative findings, post-operative complicatio...
0
In vivo evaluation of the effect of intramedullary nail microtopography on the development of local infection in rabbits
PJI DX Updated Search
BACKGROUND AND AIM: Fractures of the tibia and femoral diaphysis are commonly repaired by intramedullary (IM) nails, which are currently composed of either electropolished stainless steel (EPSS) or standard, non-polished titanium-aluminum-niobium (TAN). Once the fracture has fully healed, removal of IM nails is common,...
0
Quantitative ultrasound and bone densitometry to evaluate the risk of nonspine fractures: a prospective study
Distal Radius Fractures
The ability of quantitative ultrasound (QUS) to estimate the risk of osteoporotic fractures was evaluated in a prospective study over a mean time of 5.47 years in 254 postmenopausal women (mean age 58.06+/-7.67 years). Baseline measurements of ultrasound transmission velocity (UTV) and bone mineral density (BMD) were t...
0
Interpersonal stressors and resources as predictors of parental adaptation following pediatric traumatic injury
DoD PRF (Psychosocial RF)
The authors examined the relationship of preinjury interpersonal resources and stressors to parental adaptation following pediatric traumatic brain injury (TBI) and orthopedic injury. Parents of children with severe TBI (n = 53), moderate TBI (n = 56), and orthopedic injuries (n = 80) were assessed soon after injury, 6...
1
Antibiotic Prophylaxis in Adults With Open Tibial Fractures: What Is the Evidence for Duration of Administration? A Systematic Review
DoD SSI (Surgical Site Infections)
Open tibial fractures are common injuries after high-energy trauma such as road traffic accidents. Infection is one of the main complications of open fractures. Broad-spectrum antibiotics have been used for prophylaxis and treatment of infection in these fractures. The duration of antibiotic prophylaxis remains controv...
1
Viscosupplementation with hylan G-F 20: a 26-week controlled trial of efficacy and safety in the osteoarthritic knee
OAK 3 - Non-arthroplasty tx of OAK
Hylan G�F 20, which is derived from hyaluronan, is a highly purified, elastoviscous fluid with rheologic properties similar to those of synovial fluid in the knee joints of healthy young persons. The efficacy and safety of viscosupplementation with hylan G�F 20 were evaluated in a multicenter, double�masked clini...
1
Differences Regarding Branded HA in Italy, Part 2: Data from Clinical Studies on Knee, Hip, Shoulder, Ankle, Temporomandibular Joint, Vertebral Facets, and Carpometacarpal Joint
OAK 3 - Non-arthroplasty tx of OAK
OBJECTIVES: The aim of the current study is to collect scientific data on all branded hyaluronic acid (HA) products in Italy that are in use for intra-articular (IA) injection in osteoarthritis (OA) compared with that reported in the leaflet. METHODS: An extensive literature research was performed for all articles repo...
0
Advances in breast surgery, 2002-2012
Reduction Mammoplasty for Female Breast Hypertrophy
The past 40 years have brought dramatic changes in breast cancer treatments, resulting in a 30% reduction in breast cancer mortality. This is largely the result of new concepts tested in a steady stream of large, well-designed, coordinated clinical trials. Early trials showed that extended surgery ("local therapy") doe...
0
Dorzolamide versus pilocarpine as adjunctive therapies to timolol: a comparison of patient preference and impact on daily life
Upper Eyelid and Brow Surgery
The purpose of this study was to compare 2% dorzolamide three times daily with 2% pilocarpine four times daily to determine patient preference, tolerability, and impact on daily life in patients concurrently receiving 0.5% timolol twice daily for treatment of elevated intraocular pressure (IOP). Seventy-five patients w...
0
Total hip replacement for patients with active tuberculosis of the hip: a systematic review and pooled analysis
PJI DX Updated Search
The timing of total hip replacement (THR) in patients with active tuberculosis (TB) of the hip is controversial, because of the potential risk of reactivation of infection. There is little information about the outcome of THR in these patients. We conducted a systematic review of published studies that evaluated the ou...
0
Local Infiltration of Tranexamic Acid (TXA) in Liposuction: A Single-Surgeon Outcomes Analysis and Considerations for Minimizing Postoperative Donor Site Ecchymosis
Panniculectomy & Abdominoplasty CPG
BACKGROUND: Tranexamic acid (TXA) has gained increasing recognition in plastic surgery as a dependable adjunct capable of minimizing blood loss, ecchymosis, and edema. To date, there have been limited data on the utilization of TXA to mitigate liposuction donor site ecchymosis. OBJECTIVES: The authors sought to investi...
1
DermACELL: a novel and biocompatible acellular dermal matrix in tissue expander and implant-based breast reconstruction
Acellular Dermal Matrix
BACKGROUND: Acellular dermal matrices present a new alternative to supporting expanders and implants for breast reconstruction in breast cancer patients following mastectomy. However, some studies have suggested that acellular dermal matrix may increase the complication rates in certain clinical settings. DermACELL ace...
0
Endoscopic brow lifts über alles
Upper Eyelid and Brow Surgery
Innumerable approaches to the ptotic brow and forehead have been described in the past. Over the last twenty-five years, we have used all these techniques in cosmetic and reconstructive patients. We have used the endoscopic brow lift technique since 1995. While no one technique is applicable to all patients, the endosc...
0
Clinical Outcomes of Venous Thromboembolism in Patients with and without Cancer: The SWIss Venous ThromboEmbolism Registry (SWIVTER)
MSTS 2022 - Metastatic Disease of the Humerus
Background The association between cancer and venous thromboembolism (VTE) in producing adverse clinical outcomes requires further investigation. Methods In the Swiss Venous ThromboEmbolism Registry (SWIVTER), we compared adverse clinical outcomes between 493 patients with cancer-associated VTE and 1,569 VTE patients w...
0
Biofeedback to promote movement symmetry after total knee arthroplasty: A feasibility study
OAK 3 - Non-arthroplasty tx of OAK
STUDY DESIGN: Prospective analysis of a longitudinal cohort with an embedded comparison group at a single time point.OBJECTIVES: To determine the feasibility and effectiveness of an outpatient rehabilitation protocol that includes movement symmetry biofeedback on functional and biomechanical outcomes after total knee a...
0
The effects of therapeutic touch on patients with osteoarthritis of the knee
Surgical Management of Osteoarthritis of the Knee CPG
BACKGROUND: The purpose of this study was to determine if therapeutic touch, an alternative medicine modality, is effective in the treatment of osteoarthritis of the knee. METHODS: A single-blinded randomized control trial was conducted in a family practice center of a community hospital family practice residency progr...
0
Treatment of earthquake-related craniofacial injuries aboard the USNS Comfort during Operation Unified Response
Upper Eyelid and Brow Surgery
BACKGROUND: Craniofacial injuries secondary to earthquake-related trauma are uncommonly reported and can pose a significant reconstructive challenge. The objective of this study is to report and analyze earthquake-related craniofacial injury reconstruction and the disaster relief capabilities of a U.S. Navy hospital sh...
0
UniSpacer arthroplasty of the knee
Surgical Management of Osteoarthritis of the Knee CPG
BACKGROUND: The operative treatment of medial compartment knee arthritis is controversial. The purpose of the present study was to report the experience of a single surgeon with the UniSpacer arthroplasty for the treatment of isolated medial compartment arthritis of the knee. METHODS: From April 2002 through November 2...
0
Osteonecrosis of the knee and related conditions
Surgical Management of Osteoarthritis of the Knee CPG
Osteonecrosis (ON) of the knee is a progressive disease that often leads to subchondral collapse and disabling arthritis. Recent studies have identified three distinct pathologic entities, all of which were previously described as knee ON: secondary ON, spontaneous ON of the knee, and postarthroscopic ON. Radiographic ...
0
Towards a definition of Ancient Rare Diseases (ARD): Presenting a complex case of probable Legg-Calvé-Perthes Disease from the North Caucasian Bronze Age (2200-1650 cal BCE)
Osteochondritis Dissecans 2020 Review
OBJECTIVE: This study discusses the challenges and possibilities of establishing a definition for Ancient Rare Diseases (ARD) in a probable case of Legg-Calvé-Perthes Disease (LCPD) from the Bronze Age cemetery Kudachurt 14, situated in the Northern Caucasus. MATERIALS: We investigated the skeletal remains of a male ag...
0
Surgical treatment of grade I central chondrosarcoma
MSTS 2022 - Metastatic Disease of the Humerus
UNLABELLED: The grade of chondrosarcoma relates to the likelihood of local recurrence and metastases. Many Grade I chondrosarcomas behave benignly if aggressively, and the question arises regarding whether wide resection is essential to control the disease. We therefore asked whether intralesional surgery also could be...
1
Supracondylar femoral fractures in the frail elderly. Fractures in need of treatment
DoD LSA (Limb Salvage vs Amputation)
The investigators of this study reviewed 112 consecutive frail elderly patients with supracondylar femoral fractures to evaluate primarily functional outcomes to optimize initial treatment of these challenging patients. A high 1-year mortality rate (22%) and significant decrease in function and quality of life occurred...
0
Electrical Stimulation for Relief of Musculoskeletal Pain
AMP (Acute Meniscal Pathology)
In brief: This is a general discussion of the history, applications, and contraindications of transcutaneous neural stimulation (TNS) as well as a brief description of a study of its use after knee surgery. TNS can be used for pain relief after surgery and in conjunction with other physical modalities to decrease joint...
0
Clinical results of Hi-tech Knee II total knee arthroplasty in patients with rheumatoid athritis: 5- to 12-year follow-up
PJI DX Updated Search
BACKGROUND: Total knee arthroplasty (TKA) is a common form of treatment to relieve pain and improve function in cases of rheumatoid arthritis (RA). Good clinical outcomes have been reported with a variety of TKA prostheses. The cementless Hi-Tech Knee II cruciate-retaining (CR)-type prosthesis, which has 6 fins at the ...
0
Technique for Insertion of the Conventus Cage for Distal Radial Fracture Fixation
Distal Radius Fractures
Introduction: Use of the intramedullary Conventus DRS Cage and fragment-specific screw fixation of distal radial fractures minimizes soft-tissue trauma, leading to earlier and improved wrist and finger motion while reducing traditional complications seen with internal fixation of distal radial fractures. Indications & ...
0
Dermatan sulphate in methoxy polyethylene glycol-polylactide-co-glycolic acid scaffolds upregulates fibronectin gene expression but has no effect on in vivo osteochondral repair
Osteochondritis Dissecans 2020 Review
PURPOSE: The purpose of the study was to investigate the effect of dermatan sulphate (DS) addition to biodegradable methoxy polyethylene glycol (MPEG) substituted polylactide-co-glycolic acid (PLGA) scaffolds for cartilage repair in vitro and in vivo. METHODS: Human chondrocytes from eight patients undergoing anterior ...
0
Antibiotic prophylaxis in breast reduction surgery: A systematic review and meta-analysis
Reduction Mammoplasty for Female Breast Hypertrophy
Objective To determine the effectiveness and harm of using antibiotic prophylaxis versus placebo or no intervention in patients undergoing breast reduction surgery to prevent surgical site infection. Materials and methods A search strategy was conducted in the MEDLINE, CENTRAL, EMBASE, and LILACS databases. Searches we...
0
Serial changes in serum vitamin K1, triglyceride, cholesterol, osteocalcin and 25-hydroxyvitamin D3 in patients after hip replacement for fractured neck of femur or osteoarthritis
Management of Hip Fractures in the Elderly
Serum vitamin K1 concentrations were measured at presentation (just before surgery) and then at weekly intervals for 3 weeks in two groups of elderly patients requiring either hemiarthroplasty for fractured neck of femur (FON, n = 13) or total hip replacement for osteoarthritis of the hip (OA, n = 16). In comparison wi...
0
Median innervated hypothenar muscle: anomalous branch of median nerve in the carpal tunnel
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
A hypothenar motor branch of the median nerve in the carpal tunnel was observed and its motor function was documented by direct intraoperative nerve stimulation in two patients having carpal tunnel releases. The hypothenar branch left the median nerve at the midcarpal tunnel area. It crossed the tunnel superficial to t...
0
The influence of initial target effect-site concentrations of propofol on the similarity of effect-sites concentrations at loss and return of consciousness in elderly female patients with the Diprifusor system
Surgical Management of Osteoarthritis of the Knee CPG
Background : Whether effect-site concentrations of propofol (Cep) at loss of consciousness and return of consciousness (LOC and ROC, respectively) in elderly women using Diprifusor are similar is unclear. We investigated whether differences in initial target Cep (Ctarget) alter similarities between Cep values at LOC an...
0
Logistic regression and machine learning predicted patient mortality from large sets of diagnosis codes comparably
Hip Fx in the Elderly 2019
Objective: The objective of the study was to compare the performance of logistic regression and boosted trees for predicting patient mortality from large sets of diagnosis codes in electronic healthcare records. Study Design and Setting: We analyzed national hospital records and official death records for patients with...
0
Knee complaints in patients with normal arthroscopic findings
AMP (Acute Meniscal Pathology)
Clinical follow-up was obtained in 96 patients with knee complaints but normal arthroscopic findings (mean observation time, 10 months). About one-third had no symptoms at follow-up; in another third there was improvement; in the remaining third there were unchanged or worsened symptoms, and a clinical re-examination i...
0
From lymph to fat: complete reduction of lymphoedema
Panniculectomy & Abdominoplasty CPG
Liposuction for late-stage lymphoedema remains a controversial technique. While it is clear that conservative therapies such as combined decongestive therapy (CDT) and controlled compression therapy (CCT) should be tried in the first instance, options for the treatment of late-stage lymphoedema that is not responding t...
0
Vacuum-assisted minimally invasive surgery-An innovative method for the operative treatment of gynecomastia
Panniculectomy & Abdominoplasty CPG
BACKGROUND: Gynecomastia is the most common benign enlargement of the mammary gland and adipose tissue in males. Because a feminine-looking chest contour can bring severe psychologic burden to patients, subcutaneous mastectomy has become the standard treatment for this condition. Conventional open surgery causes conspi...
0
Ipsilateral obturator type of hip dislocation with fracture shaft femur in a child: A case report and literature review
Pediatric Diaphyseal Femur Fractures 2020 Review
The incidence of traumatic hip dislocations in children is rising in this fast developing world along with increasing numbers of high-velocity road traffic accidents. Anterior dislocation of the hip has a lower incidence compared with posterior dislocation of the hip. We encountered a rare case of the obturator type of...
1
American Society of Clinical Oncology guideline on the role of bisphosphonates in breast cancer
MSTS 2018 - Femur Mets and MM
Purpose: To determine clinical practice guidelines for the use of bisphosphonates in the prevention and treatment of bone metastases in breast cancer and their role relative to other therapies for this condition. Methods: An expert multidisciplinary panel reviewed pertinent information from the published literature and...
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Ultrasound properties of articular cartilage in the tibio-femoral joint in knee osteoarthritis: relation to clinical assessment (International Cartilage Repair Society grade)
AMP (Acute Meniscal Pathology)
INTRODUCTION: There is a lack of data relating the macroscopic appearance of cartilage to its ultrasound properties. The purpose of the present study was to evaluate degenerated cartilage and healthy-looking cartilage using an ultrasound system. METHODS: Ultrasound properties--signal intensity (a measure of superficial...
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Knowledge and reported practice of antibiotic prescription by dentists for common oral problems
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
OBJECTIVE: To assess the knowledge and reported practice in relation to antibiotic prescribing regarding common oral problems by dentists in Karachi, Pakistan. STUDY DESIGN: Cross-sectional survey. PLACE AND DURATION OF STUDY: Three Dental Colleges of Karachi, from July to December 2010. METHODOLOGY: The cross-sectiona...
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Subtrochanteric femoral fractures
Management of Hip Fractures in the Elderly
Femoral fractures in the subtrochanteric and proximal shaft regions require special management because of the great stresses inflicted on the area. Stability is best achieved with intramedullary fixation when there is adequate control of both proximal and distal fragments. Intertrochanteric fractures with small subtroc...
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The treatment of fracture-dislocation of the hip by total hip arthroplasty
Management of Hip Fractures in the Elderly
Five patients with chronic and subacute unreduced fracture-dislocation of the hip were treated successfully by total hip arthroplasty. The regimen developed was as follows: The first stage, in general, consisted of removal of the head of the femur and reduction and internal fixation of the acetabular fragments. Surgery...
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Head and neck replacement endoprosthesis for pathologic proximal femoral lesions
Management of Hip Fractures in the Elderly
Records of 28 patients with pathologic lesions in the proximal femur treated by implantation of a femoral head and neck replacement prosthesis between 1984 and 1995 were reviewed. Mean clinical followup was 47.8 months in the eight living patients and 15.8 months in the 20 patients who had died. The underlying diagnosi...
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The Value of Early Mobilization and Physiotherapy Following Wrist Fractures Treated by Volar Plating
Distal Radius Fractures
A prospective, randomized study investigating the possible benefits of immediate mobilization and frequent physiotherapy following a wrist fracture treated by volar plating. The current study will test the following null hypothesis: There is no significant difference between patients who receive a cast for the first 2 ...
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Failure of a properly positioned tantalum rod for treatment of early femoral head necrosis and conversion to total hip arthroplasty
AAHKS (2) Corticosteroids
Background: Conventional core decompression (CD) is a well-known procedure for treatment of avascular necrosis of the femoral head. Weight bearing is usually restricted in the early postoperative weeks to avoid the risk of fracture. Theoretically, a properly positioned implantation of the new tantalum rod after reaming...
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Evaluation of a shape memory staple (Qual R) in radial shortening osteotomy in Kienbock's disease: A retrospective study of 30 cases
Distal Radius Fractures
The QUAL R (Memometal, Stryker) device is a shape memory staple used for bone fixation during distal radius shortening osteotomy in the context of Kienbock's disease. The present study is a retrospective, single-center and multisurgeon study of 30 patients with a mean follow-up of 8 years. Clinical criteria (range of m...
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Distal Femoral Fresh Osteochondral Allografts: Follow-up at a Mean of Twenty-two Years
DoD LSA (Limb Salvage vs Amputation)
BACKGROUND: Osteochondral defects of the knee in young, active patients represent a challenge to the orthopaedic surgeon. Our study examined long-term outcomes of the use of fresh allograft for posttraumatic osteochondral and osteochondritis dissecans defects in the distal aspect of the femur. METHODS: We reviewed the ...
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Ultra low-dose naloxone and tramadol/acetaminophen in elderly patients undergoing joint replacement surgery: a pilot study
AAHKS (8) Anesthetic Infiltration
OBJECTIVE: A pilot study was conducted to assess whether both the rationale and feasibility exist for future randomized clinical trials to evaluate the combined use of naloxone infusion and tramadol/acetaminophen as opioid-sparing drugs in elderly patients undergoing lower extremity joint replacement surgery. DESIGN: T...
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Comparison of T2 relaxation times of articular cartilage of the knee in elite professional football players and age-and BMI-matched amateur athletes
OAK 3 - Non-arthroplasty tx of OAK
OBJECTIVE: Recent investigation has underlined the potential of quantitative MR imaging to be used as a complementary tool for the diagnosis of cartilage degeneration at an early state. The presented study analyses T2* relaxation times of articular cartilage of the knee in professional athletes and compares the results...
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Septic arthritis after arthroscopic anterior cruciate ligament reconstruction
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
INTRODUCTION: A retrospective review of postoperative infected anterior cruciate ligament (ACL) reconstruction was done on 472 consecutive cases in one institution. The purpose was to assess the incidence, diagnosis, treatment and outcome factors. MATERIALS AND METHODS: Out of 472 arthroscopic-assisted ACL reconstructi...
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Distress, suicidal thoughts, and social support among homeless adults
DoD PRF (Psychosocial RF)
Influences on psychological distress and suicidal thoughts are evaluated with a sample of 218 sheltered homeless adults. Levels of distress and suicidal thoughts are much higher than in the general population, and are comparable to those found by Rossi (1989). Perceived social support lessens distress and suicidal thou...
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Hamulus fracture
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Fracture of the hook of the hamate is a rare problem. However, the emergency physician must have the clinical sophistication to recognize hypothenar and dorso-ulnar wrist tenderness, to evaluate ulnar nerve function, to order a carpal tunnel view, and to initiate appropriate referral in order to eliminate symptoms, dis...
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Prevention of hip fractures: drug therapy
Management of Hip Fractures in the Elderly
Drug therapy to prevent hip fractures may be considered for postmenopausal women with low bone mass and elderly people with risk factors for hip fracture. As most hip fractures occur 25 years or more after menopause, drug therapy may have to be prescribed for many years to be effective. A preventative drug should be ef...
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Translation, cross-cultural adaptation and validation of the Turkish version of the Lower Extremity Functional Scale on patients with knee injuries
OAK 3 - Non-arthroplasty tx of OAK
Introduction: The Lower Extremity Functional Scale is a widely used questionnaire to evaluate the functional impairment in lower extremities. To date, the Lower Extremity Functional Scale has not been translated into Turkish. The aim of this study is to translate and culturally adapt the Lower Extremity Functional Scal...
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A prospective cohort study of the clinical presentation of non-traumatic osteonecrosis of the femoral head: spine and knee symptoms as clinical presentation of hip osteonecrosis
AAHKS (2) Corticosteroids
PURPOSE: To study the clinical presentation of femoral head osteonecrosis (ONFH). Publications dedicated to this aspect of ONFH are rare. Our aim was to systematically collect and describe the clinical data. METHODS: A prospective survey was conducted in a cohort of ONFH recruited from a dedicated clinic for osteonecro...
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Hand strengths in carpal tunnel syndrome
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
The purpose of this study was to determine whether a measurable decrease in isokinetic (dynamic) and isometric (static) hand strengths occurs in carpal tunnel syndrome (CTS) patients. Eighteen CTS patients and 20 healthy controls were included in the study. Isokinetic (eccentric and concentric) and isometric grip and p...
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Displaced femoral neck fractures in the elderly: hemiarthroplasty versus total hip arthroplasty
Management of Hip Fractures in the Elderly
The incidence of femoral neck fracture among the elderly in the United States is expected to increase dramatically because of the anticipated explosion in the population aged 65 years and older, increased life expectancy, and the rising incidence of osteoporosis. The resulting public health implications may be signific...
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Acute aquatic treadmill exercise improves gait and pain in people with knee osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
OBJECTIVE: To examine the acute effects of aquatic and land treadmill exercise on gait kinematics as well as the level of disease-specific and movement-related pain for individuals with osteoarthritis. DESIGN: Quasi-experimental crossover design. SETTING: Biomechanics laboratory. PARTICIPANTS: Participants (N=14; age, ...