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Meniscectomy
AMP (Acute Meniscal Pathology)
Meniscal injury is a common cause of knee pain and major cause of functional impairment of the knee at young athletic population. Although the menisci were thought to be a vestigial tissue and treated with disrespect as an unnecessary appendage for many years; today it is known that the menisci provide mechanical suppo...
0
Outcome of Unicondylar Knee Arthroplasty vs Total Knee Arthroplasty for Early Medial Compartment Arthritis: A Randomized Study
OAK 3 - Non-arthroplasty tx of OAK
Background With increasing number of patients with early osteoarthritis of knee opting for total knee arthroplasty (TKA), there has been increase in patients dissatisfied with surgical outcomes. It is being presumed that offering unicondylar knee arthroplasty (UKA) to them would improve outcomes. Methods Primary object...
0
Valdecoxib: a review of its use in the management of osteoarthritis, rheumatoid arthritis, dysmenorrhoea and acute pain
Surgical Management of Osteoarthritis of the Knee CPG
Valdecoxib is an orally administered, highly selective cyclo-oxygenase (COX)-2 inhibitor with anti-inflammatory and analgesic properties. In well designed trials, valdecoxib demonstrated efficacy versus placebo in patients with osteoarthritis (OA), rheumatoid arthritis (RA), primary dysmenorrhoea and postoperative pain...
0
Effectiveness of preventive and corrective surgical intervention on hip disorders in severe cerebral palsy: a systematic review
SR for PM on OA of All Extremities
Abstract Purpose: This review presents an overview of the effectiveness of preventive and corrective surgical interventions to treat hip displacement in patients with severe cerebral palsy (CP). Method: A systematic literature search was applied to identify studies concerning surgical procedures in hip(sub)luxations in...
0
Short scar mastopexy with flap transposition
Reduction Mammoplasty for Female Breast Hypertrophy
A personalized technique using a vertical scar mastopexy is described. The breast tissue is utilized as a transposition flap behind the nipple- areolar complex to increase its projection. The inferior pole of the breast can be developed either as a superiorly pedicled or inferiorly pedicled flap for that purpose and th...
0
Lesions of the scapholunate ligaments in acute wrist trauma--arthroscopic diagnosis and minimally invasive treatment
Distal Radius Fractures
The final result of the treatment of distal intra-articular radius fractures depends both on the accuracy of the fracture reduction and on the presence of additional carpal injuries. In particular, lesions of the intrinsic ligaments usually lead to severe degenerative damage of the wrist joint if they are missed primar...
0
Arthroscopic meniscal suture with the "double-loop technique"
AMP (Acute Meniscal Pathology)
A new personal technique of arthroscopic meniscal suture in which the knots are all inside the knees, fixed only in the meniscus is presented. Using a new tool, a flexible double-loop allows the suture in the posterior horn of the meniscus to pass the suture from the anterior portal to the posterior portal without the ...
0
Median nerve suture in the distal part of the forearm. MRI evaluation
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
The aim of the study was to assess MR images of median nerve suture in the distal part of the forearm on fresh cadavers and injured patients. The median nerve was dissected in the distal one-third of the forearm in four fresh cadaveric specimens, divided and repaired in three of them in two cases with 3/0 nylon (one wi...
0
Healthcare utilization and costs of knee or hip replacements versus pain-relief injections
AAHKS (2) Corticosteroids
BACKGROUND: Given the dramatic increase in total knee and hip replacement procedures among the US population aged 45 years and older, there is a need to compare the downstream healthcare utilization and costs between patients who undergo joint replacement and those who receive intraarticular injections as a low-cost al...
0
Locking versus non-locking plates in fixation of extra-articular distal humerus fracture: a randomized controlled study
Pediatric Supracondylar Humerus Fracture 2020 Review
INTRODUCTION: Studies have shown that the use of nonlocking (reconstruction) plates in fixing distal humerus fractures may not yield stable fixation which therefore requires long immobilization and suboptimal functional results. There are reports showing that locking plates are biomechanically superior to nonlocking pl...
1
Identification of bacteria in endodontic infections by sequence analysis of 16S rDNA clone libraries
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
A significant proportion of oral bacteria are unable to undergo cultivation by existing techniques. In this regard, the microbiota from root canals still requires complementary characterization. The present study aimed at the identification of bacteria by sequence analysis of 16S rDNA clone libraries from seven endodon...
0
The health-related quality of life and cost implications of falls in elderly women
Management of Hip Fractures in the Elderly
Summary: Fractures and falls are serious cause of morbidity and cost to society. Our results suggest that the main burden to morbidity, measured as impact on health-related quality of life, is due to fear of falling rather than falls or their sequelae, such as fractures. Introduction: Fractures and falls are serious ca...
0
Translational potential of ginsenoside Rb1 in managing progression of osteoarthritis
AMP (Acute Meniscal Pathology)
BACKGROUND: Osteoarthritis (OA) is the most common degenerative joint disorder. Inflammatory cytokine plays an important role in OA progression. Previous studies have demonstrated that ginsenoside Rb1 would prevent inflammation and apoptosis in chondrocytes. However, we have not found any animal study reporting that Rb...
0
Postoperative analgesic and adverse effects of two low doses of intrathecal neostigmine and its influence on spinal bupivacaine anaesthesia after knee arthroscopy
Surgical Management of Osteoarthritis of the Knee CPG
Background: Neostigmine is a spinal analgesic that could be a useful adjunct. This study was conducted to evaluate the postoperative analgesic efficacy and the safety of two low doses of intrathecal (IT) neostigmine in patients undergoing knee arthroscopy under spinal bupivacaine anaesthesia. Methods: By using a double...
0
Tibial torsion: cause or consequence of osteoarthritis?
OAK 3 - Non-arthroplasty tx of OAK
OBJECTIVE: The purpose of this study was to evaluate the relationship between torsional variations of the lower extremity and the development of medial osteoarthritis in the knee. METHODS: Computed tomography measurements of the femoral and tibial torsion were evaluated in 21 lower extremities of 19 patients with prima...
0
Does intermeniscal ligament tenodesis affect meniscal allograft extrusion? Retrospective comparative study at a minimum follow-up of 2 years
AMP (Acute Meniscal Pathology)
INTRODUCTION: Meniscal allograft transplantation (MAT) is indicated for the treatment of post-meniscectomy syndrome in young patients who do not have severe cartilage loss. While its clinical effectiveness is well established in the short- and mid-term, it does not appear to stop the progression of osteoarthritis. Meni...
0
Intrapartum antibiotic prophylaxis increases the incidence of gram-negative neonatal sepsis
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
OBJECTIVE: To investigate the influence of the increased use of intrapartum chemoprophylaxis on the incidence of vertically transmitted neonatal sepsis. METHODS: Multiple institutional databases were queried for the number of cases in which intrapartum antibiotics were used, the obstetric risk factors that were present...
0
Early impairment of foveal magno- and parvocellular pathways in juxta chiasmal tumours
Upper Eyelid and Brow Surgery
Foveal pathway visual function was assessed in 11 patients having tumours extending into the suprasellar region but without evidence of visual impairment as assessed by visual acuity and Bjerrum screen campimetry. Psychophysical and routine visual evoked potential (VEP) measurements were obtained from the eye ipsilater...
0
Epidemiology of hallucinogen use in the U.S. results from the National epidemiologic survey on alcohol and related conditions III
DoD PRF (Psychosocial RF)
BACKGROUND: Population-based data regarding the epidemiology of hallucinogen use and co-occurring psychiatric disorders is largely absent from the literature. We aim to present findings on the prevalence, sociodemographic correlates, psychiatric comorbidity, treatment utilization, social support and associated disabili...
0
Utilization and costs of formal and informal care, home adaptations, and physiotherapy among older patients with hip fracture
Hip Fx in the Elderly 2019
Aims: This feasibility study investigates the utilization and cost of health resources related to formal and informal care, home adaptations, and physiotherapy among patients aged 60 years and above after hip fracture from a multicentre cohort study (World Hip Trauma evaluation (WHiTe)) in the UK. Methods: A questionna...
0
Contemporary Results of Surgical Management of Peripheral Mycotic Aneurysms
DoD LSA (Limb Salvage vs Amputation)
BACKGROUND: Mycotic aneurysms of the extremities occur infrequently but can cause severe life and limb complications. Traditional treatment typically includes debridement and revascularization, though in select patients ligation may be well tolerated. We reviewed our experience with these aneurysms treated with these 2...
0
Goal Management Training Combined With External Cuing as a Means to Improve Emotional Regulation, Psychological Functioning, and Quality of Life in Patients With Acquired Brain Injury: A Randomized Controlled Trial
DoD PRF (Psychosocial RF)
OBJECTIVE: To investigate whether goal management training (GMT) expanded to include external cuing and an emotional regulation module is associated with improved emotional regulation, psychological functioning, and quality of life (QOL) after chronic acquired brain injury (ABI). DESIGN: Randomized controlled trial wit...
0
Timed instrumental activities of daily living tasks: relationship to visual function in older adults
Upper Eyelid and Brow Surgery
PURPOSE: To identify instrumental activities of daily living (IADL) tasks whose completion time is related to visual function in older adults. METHODS: Visual function (acuity, contrast sensitivity, and useful field of view) and the time to complete 17 visual tasks of everyday life were measured in a sample of 342 olde...
0
Principles of surgical treatment of congenital, developmental and acquired female breast asymmetries
Reduction Mammoplasty for Female Breast Hypertrophy
BACKGROUND/AIM: There is a natural asymmetry in normal female brests. When the difference in the shape, size or position of the breast and nipple-areola complex is visible, surgical correction is the only treatment option and presents one of the greatest challenges for a plastic surgeon. Based on the Nahai classificati...
0
Human histologic evaluation of a bone graft combined with GTR in the treatment of osseous dehiscence defects: a case report
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
There are many possible goals and outcomes of periodontal surgical therapy, but the ultimate goal is regeneration. Since the definition of periodontal regeneration is histologic, it is difficult to document. The purpose of this study was to evaluate a technique that combined a bone graft and guided tissue regeneration ...
0
Trauma in elderly people: What proportion of fractures are a consequence of bone fragility?
Management of Hip Fractures in the Elderly
Epidemiologists have tended to equate osteoporotic fractures with those which occur after only moderate trauma, or which affect elderly people. We set out to critically examine this epidemiological approach, because even among elderly people some fractures will be a result of severe trauma and these cannot be assumed t...
1
A Systematic Review of Adverse Events and Complications After Isolated Posterior Medial Meniscus Root Repairs
AMP (Acute Meniscal Pathology)
BACKGROUND: Medial meniscus posterior root (MMPR) tears are recognized as a substantial cause of disability and morbidity. However, meniscus root repair, regardless of technique, is not without potential complications. PURPOSE: To evaluate the reported incidence of complications and adverse events after isolated MMPR r...
0
Comparison of patients in three different rehabilitation settings after knee or hip arthroplasty: A natural observational, prospective study
OAK 3 - Non-arthroplasty tx of OAK
Background: Patients after primary hip or knee replacement surgery can benefit from postoperative treatment in terms of improvement of independence in ambulation, transfers, range of motion and muscle strength. After discharge from hospital, patients are referred to different treatment destination and modalities: inten...
0
Does cognitive/physical screening in an outpatient setting predict institutionalization after hip fracture?
Hip Fx in the Elderly 2019
BACKGROUND: Institutionalization after hip fracture is a socio-economical burden. We examined the predictive value of Instrumental Activities of Daily Living (IADL) and Mini Mental State Examination (MMSE) for institutionalization after hip fracture to identify patients at risk for institutionalization. METHODS: Fragil...
0
Dehydroepiandrosterone (DHEA) replacement reduces growth hormone (GH) dose requirement in female hypopituitary patients on GH replacement
AAHKS (2) Corticosteroids
OBJECTIVE: GH dose requirement is lower in ACTH replete compared with ACTH deficient hypopituitary patients suggesting that adrenal androgens may augment IGF-I generation for a given GH dose. This study aimed to determine the effect of dehydroepiandrosterone (DHEA) administration on GH dose requirements in hypopituitar...
0
Prognostic factors in localized soft-tissue sarcomas
MSTS 2022 - Metastatic Disease of the Humerus
The prognostic factors associated with local failure and overall survival and the effect of radiotherapy were determined in 77 patients with localized (extremity and nonextremity) operable soft-tissue sarcoma. There were 52 male and 25 female patients; median age was 50 years (range: 15-83). Histologic grade of the tum...
1
Survivorship Between 2 Different Ceramic-on-Ceramic Total Hip Arthroplasty With or Without a Metal-Backed Titanium Sleeve Bearing: A 5- to 14-Year Follow-Up Study
Hip Fx in the Elderly 2019
BACKGROUND: The aim of the study was to compare the clinical and radiographic results of consecutive ceramic-on-ceramic bearings with and without a metal-backed titanium sleeve in patients undergoing total hip arthroplasty. METHODS: Eighty-five patients (64 women and 21 men; average age 55.2 years) were included in the...
0
Classification of knee osteoarthritis according to spatiotemporal gait analysis
Surgical Management of Osteoarthritis of the Knee CPG
Methods: Gait analysis of 2,900 patients from AposTherapy dataset (AposTherapy, Herzeliya, Israel) suffering from knee OA were included in the study. Men and women were analyzed separately. The analysis included three stages - clustering, classification and clinical validation. Clustering of gait analysis data by the k...
0
Bacterial endocarditis: risk factors in Cork dental hospital patients
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
An examination was carried out of the records of 2500 patients who attended the University Dental School and Hospital, Cork, Republic of Ireland during the period 1981-1986. 3.6% of these patients were found to have factors which put them at risk of developing bacterial endocarditis. Mention is made of the level of ris...
0
The local effects of metal corrosion in total hip arthroplasty
PJI DX Updated Search
Corrosion has long been recognized to occur in total hip arthroplasty, but the local effects of this process have only recently become better understood. This article provides an overview of corrosion at modular junctions, and discusses the various etiologic factors for corrosion and the biologic response to metal debr...
0
Outcome of revision for mechanical stem failure using the cemented Charnley's stem
Management of Hip Fractures in the Elderly
Three hundred ninety-nine cemented stem revision total hip arthroplasties performed in cases with mechanical stem failure without infection and having a minimum follow-up period of 3 years were prospectively studied. Two hundred eighty-three were revised for aseptic stem loosening and 116 were revised for fractured ste...
0
Clinical and experimental evaluation of the thromboprophylactic effect of hydroxychloroquine sulfate after total hip replacement
AAHKS (8) Anesthetic Infiltration
The rate of postoperative deep vein thrombosis was studied by the 125I-fibrinogen method in 35 patients after total hip replacement. 12 out of 18 patients treated prophylactically with hydroxychloroquine sulfate developed deep vein thrombosis compared with 11 out of 17 patients in the control group. Platelet aggregabil...
1
Orthodromic sensory conduction along the ring finger in normal subjects and in patients with a carpal tunnel syndrome
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
The purpose of the present study was to examine the value of measuring sensory conduction along the median and ulnar nerves of the fourth finger in the diagnosis of a carpal tunnel syndrome (CTS). In 23 controls, sensory conductions along median and ulnar nerves were identical. In 28 of 38 patients with CTS, stimulatio...
1
An effective antibiotic cover for the prevention of endocarditis following dental and other post-operative bacteraemias
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
Pre- and post-extraction blood cultures were taken from 242 patients. The post-extraction ones were taken from 100 unpremedicated patients, from 42 with an erythromycin estolate cover, and from 100 patients after protection with pyrrolidino methyl tetracycline. The 100 post-extraction blood cultures from unpremedicated...
0
High body mass index is associated with increased diurnal strains in the articular cartilage of the knee
OAK 3 - Non-arthroplasty tx of OAK
OBJECTIVE: Obesity is an important risk factor for osteoarthritis (OA) and is associated with changes in both the biomechanical and inflammatory environments within the joint. However, the relationship between obesity and cartilage deformation is not fully understood. The goal of this study was to determine the effects...
0
Do demographic and perioperative parameters really affect the final outcomes of pediatric femur shaft fractures managed by elastic nails? A prospective study
DoD SSI (Surgical Site Infections)
Objective: Pediatric femoral shaft fractures are more commonly treated with intramedullary titanium elastic nail system (TENS). Adhering to the principles, most studies had supported excellent results with this instrumentation and attributed the variation in age, weight, immobilization protocols, technical factors like...
0
Subtrochanteric fracture after Garden screw fixation: a review of predisposing factors and management in nine cases
Management of Hip Fractures in the Elderly
Nine cases of subtrochanteric fracture are reviewed following 300 fixations of subcapital fractures with Garden screws. In six cases technical operative errors were considered to contribute to the fracture. It is stressed that adequate reduction and suitably placed crossed Garden screws are demanding requirements and t...
0
The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: A mendelian randomisation study
SR for PM on OA of All Extremities
Objective: Variation in the fat mass and obesity-associated (FTO) gene influences susceptibility to obesity. A variant in the FTO gene has been implicated in genetic risk to osteoarthritis (OA). We examined the role of the FTO polymorphism rs8044769 in risk of knee and hip OA in cases and controls incorporating body ma...
1
Concomitant posterior anchoring further reduces posterior meniscal extrusion during pullout repair of medial meniscus posterior root tears: a retrospective study
AMP (Acute Meniscal Pathology)
PURPOSE: Transtibial pullout repair improves the clinical outcomes of medial meniscus (MM) posterior root tears (PRTs); however, reducing MM extrusion remains challenging. Thus, the purpose of this study was to examine the role of additional posterior anchoring (PA) during pullout repair in reducing the severity of MM ...
0
Implantation of autogenous meniscal fragments wrapped with a fascia sheath enhances fibrocartilage regeneration in vivo in a large harvest site defect
AMP (Acute Meniscal Pathology)
BACKGROUND: Concerning meniscal tissue regeneration, many investigators have studied the development of a tissue-engineered meniscus. However, the utility still remains unknown. HYPOTHESIS: Implantation of autogenous meniscal fragments wrapped with a fascia sheath into the donor site meniscal defect may significantly e...
0
Pathophysiology of surgical site infection in total hip arthroplasty
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
This article is a case report of a 69-year-old man who underwent a right total hip replacement procedure and developed a surgical site infection. Areas of concern in prevention and treatment of hip arthroplasty infection are presented, focusing on the pathophysiologic process involved. A review of the patient risk fact...
0
Efficacy and safety of 3D-conformal half body irradiation in patients with multiple bone metastases
MSTS 2018 - Femur Mets and MM
Half-body irradiation (HBI) represented a standard treatment for multiple painful bone metastases (BMs). However, its use has progressively reduced due to the associated toxicity rates. The aim of this paper was to evaluate HBI delivered by conformal radiotherapy (RT) technique in a large patients population with wides...
1
Rates and odds ratios for complications in closed and open tibial fractures treated with unreamed, small diameter tibial nails: A multicenter analysis of 467 cases
DOD - Acute Comp Syndrome CPG
Objective: A multicenter trial analyzed complications and odds for complications in open and closed tibial fractures stabilized by small diameter nails. Design: Retrospective. Setting: Four Level I trauma centers. Patients: Four hundred sixty-seven tibial fractures were included in the study. There were fifty-two proxi...
0
Modified mini-Hardinge access for hip prosthesis implantation in the supine position
DoD SSI (Surgical Site Infections)
OBJECTIVE: Total hip arthroplasty with a minimal-incision technique that can be performed in the widely used supine position. The accustomed and good overview of this position allows safe positioning of the implant and combines this with the advantage of a soft tissue preserving technique. All standard instruments and ...
0
Complications in Eyelid Surgery
Upper Eyelid and Brow Surgery
Eyelid surgery consists of challenging reconstructive and cosmetic procedures. Because of the complex anatomy and corresponding vital functions of the upper and lower eyelids, the avoidance of eyelid complications is of vital importance. Complications after eyelid surgery include basic complications (infection, granulo...
0
Etiology and prevention of age-related hip fractures
Management of Hip Fractures in the Elderly
Falls and fall-related injuries are among the most serious and common medical problems experienced by the elderly. Hip fracture, one of the most severe consequences of falling in the elderly, occurs in only about 1% of falls. Despite this, hip fracture accounts for a large share of the disability, death, and medical co...
0
Bicruciate retaining
OAK 3 - Non-arthroplasty tx of OAK
Total knee replacement (TKR) is a procedure used to treat knee arthropathy. Patients' dissatisfaction is still relevant (literature reports dissatisfaction rates as high as 40%). The anterior cruciate ligament is usually removed while performing a total knee arthroplasty, thus changing knee biomechanics. As patients' m...
0
The case for evidence in wound care: investigating advanced treatment modalities in healing chronic diabetic lower extremity wounds
DoD LSA (Limb Salvage vs Amputation)
BACKGROUND: Major complications of diabetes mellitus include lower leg and foot ulcers, which can result in amputation. Further study is needed to determine optimal treatments for these challenging wounds. Growth factor therapy and hyperbaric oxygen (HBO) treatments are 2 advanced therapeutic modalities that hold promi...
0
Treatment results with debridement and retention of infected hip prostheses
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
A retrospective systematic review of the management of a periprosthetic joint infection (PJI) cohort of 78 cases was conducted at a single-centre, middle-sized Norwegian hospital from 1997 to 2007. We analysed 40 cases that were managed by surgical debridement with hip prosthesis retention followed by long-lasting path...
0
Carpal tunnel syndrome in a patient with a Cimino-Brescia fistula
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
A case of a carpal tunnel syndrome in a patient with chronic renal insufficiency undergoing hemodialysis by means of a Cimino-Brescia arteriovenous fistula is reported. Surgical decompression of the median nerve at the wrist was followed by the immediate and complete relief of the patient's symptoms. Ischemia related t...
1
Histological findings in breast tissue specimens from reduction mammoplasties
Reduction Mammoplasty for Female Breast Hypertrophy
Tissue specimens from 55 consecutive reduction mammoplasty operations were studied histologically for changes considered to be associated to an increased risk in the development of invasive breast cancer. A thorough sampling of all removed tissues was performed and nearly all solid parts were processed for histological...
1
Preoperative cardiac evaluation of patients with acute hip fracture
Management of Hip Fractures in the Elderly
The goals of the present study were to assess if there is an association between preoperative cardiac evaluation and surgery timing in patients with a hip fracture, to evaluate the relationship between surgery timing and postoperative morbidity and mortality, and to determine if the proper patients are being selected f...
0
Case report: Capnocytophaga canimorsus a novel pathogen for joint arthroplasty
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
We report the case of a 59-year-old man with Waldenstrom's macroglobulinemia and active alcohol use who presented with bilateral knee pain 5 years after a bilateral staged TKA. Cultures of synovial fluid and periprosthetic tissue specimens from both knees yielded, after prolonged anaerobic incubation, a catalase- and o...
0
Stability of total hip arthroplasty in patients 75 years or older
Management of Hip Fractures in the Elderly
Increasing patient age (> 75 years) is a known risk factor for dislocation of total hip arthroplasty. This is a study of total hip arthroplasties by one surgeon in patients 75 years or older to determine the prevalence of dislocation and a review of the surgical options for prevention and treatment of instability in th...
0
Acromioclavicular joint arthrosis in persons with spinal cord injury and able-bodied persons
Glenohumeral Joint OA
OBJECTIVE: To compare the prevalence, severity and risk of acromioclavicular (AC) joint arthrosis in persons presenting with shoulder pain between a spinal cord injury (SCI) and able-bodied population. In the SCI population, prevalence and severity of AC joint arthrosis were examined with respect to age, gender and les...
1
Functional and radiographic outcomes of Gartland type II supracondylar humerus fractures managed by closed reduction under nitrous oxide as conscious sedation
Pediatric Supracondylar Humerus Fracture 2020 Review
The management of Gartland type II supracondylar fractures remains controversial. This study aimed to evaluate the clinical, functional, and radiographic outcomes of Gartland type II supracondylar fractures treated by immediate closed reduction and casting in the emergency department using equimolar nitrous oxide as co...
0
Sublinear elliptic problems with a Hardy potential
Glenohumeral Joint OA
Purpose: Arthralgia occurs in up to 50% of breast cancer survivors treated with aromatase inhibitors (AIs) and is the most common reason for poor AI adherence. We conducted, in 121 breast cancer survivors receiving an AI and reporting arthralgia, a yearlong randomized trial of the impact of exercise versus usual care o...
0
Malalignment after minimally invasive plate osteosynthesis in distal femoral fractures
Pediatric Diaphyseal Femur Fractures 2020 Review
INTRODUCTION: Although minimally invasive plate osteosynthesis (MIPO) is a preferred operative treatment for fractures of the distal femur, malalignment is a significant concern because of indirect reduction of the fracture. The purpose of this study, therefore, was to evaluate radiologic alignment after MIPO for dista...
0
Osteochondral allografts: applications in treating articular cartilage defects in the knee
Surgical Management of Osteoarthritis of the Knee CPG
Chondral injury in the knee is a unique challenge to the orthopaedic surgeon. Given the high probability of progression to knee arthrosis, the treatment of symptomatic cartilage defects of the knee has become an important surgical intervention in young, active patients. The demand for an alternative to prosthetic resur...
0
Renal cell carcinoma detection and systemic therapy with tumour-affine gallium-67 and with yttrium-90 citrate solutions
MSTS 2018 - Femur Mets and MM
BACKGROUND: There have been no major advances in the systemic detection of renal cell carcinoma (RCC) and its unpredictable metastases. Surgery, thus, remains the mainstay of the curative treatment for the localized disease. The propose of the present study has been to systemically detect and treat advanced RCC respect...
0
Efficacy, safety, tolerability and pharmacokinetics of a novel human immune globulin subcutaneous, 20%: a Phase 2/3 study in Europe in patients with primary immunodeficiencies
DoD SSI (Surgical Site Infections)
A highly concentrated (20%) immunoglobulin (Ig)G preparation for subcutaneous administration (IGSC 20%), would offer a new option for antibody replacement therapy in patients with primary immunodeficiency diseases (PIDD). The efficacy, safety, tolerability and pharmacokinetics of IGSC 20% were evaluated in a prospectiv...
0
Extracorporeally frozen tumour-bearing bone combined with free vascularised fibula for the intercalary reconstruction of femoral defect after resection of bony sarcoma
PJI DX Updated Search
BACKGROUND: With the improved survival for patients with bone sarcomas, there is a trend to reconstruct intercalary femur defects using biologic techniques. This study examined whether the results of a frozen femur autograft with vascularised fibula are comparable to other reconstructive options in terms of the functio...
0
Spine-Hip T-Score Difference Predicts Major Osteoporotic Fracture Risk Independent of FRAX((registered trademark)): A Population-Based Report From
Management of Hip Fractures in the Elderly
The WHO fracture risk assessment tool (FRAX((registered trademark))) estimates an individual's 10-yr major osteoporotic and hip fracture probabilities. When bone mineral density (BMD) is included in the FRAX calculation, only the femoral neck measurement can be used. Recently, a procedure was reported for adjusting maj...
1
Effectiveness and safety of continuous ultrasound-guided femoral nerve block versus epidural analgesia after total knee arthroplasty
AAHKS (9/10) Regional Nerve Blocks
OBJECTIVES: Total knee arthroplasty is associated with severe postoperative pain. The aim of this study was to compare continuous ultrasound-guided femoral nerve block with continuous epidural analgesia, both with low concentrations of local anaesthetic after total knee arthroplasty. MATERIAL AND METHODS: A prospective...
1
Open versus Endoscopic Carpal Tunnel Release: A Meta-analysis of Randomized Controlled Trials
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
BACKGROUND: Carpal tunnel syndrome is a common compressive neuropathy of the median nerve. The efficacy and safety of endoscopic versus open carpal tunnel release remain controversial. QUESTIONS/PURPOSES: The purpose of this study was to determine whether endoscopic compared with open carpal tunnel release provides bet...
0
Shortwave ultraviolet radiation in operating rooms
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
We have evaluated the effect of shortwave ultraviolet radiation on bacterial levels in an operating theatre, both in experimental conditions and during 20 hip operations. When compared with the use of sham blue light, there was a significant reduction in the number of bacteria. The reduced level was comparable with tha...
0
Percutaneous Pins Versus Volar Plates for Unstable Distal Radius Fractures: A Biomechanic Study Using a Cadaver Model
Distal Radius Fractures
Purpose: A biomechanic study using a cadaver model of a dorsally unstable distal radius fracture was used to compare the stability of percutaneous pinning and volar fixed-angle plating. Among the many surgical options for treating distal radius fractures are percutaneous pinning and internal plate fixation. Although pe...
0
Radiofrequency lumbar sympatholysis. The evolution of a technique for managing sympathetically maintained pain
Surgical Management of Osteoarthritis of the Knee CPG
BACKGROUND AND OBJECTIVES: To develop lumbar radiofrequency sympatholysis for the relief of pain in patients with neuropathic pain who had previously responded to sympathectomy or sympathetic blocks. METHODS: The technique described by Sluijter was modified to attempt to obtain long lasting pain relief in each patient....
0
Selective inhibition of matrix metalloproteinase-2 in the multiple myeloma-bone microenvironment
MSTS 2018 - Femur Mets and MM
Multiple myeloma is a plasma cell malignancy that homes aberrantly to bone causing extensive skeletal destruction. Despite the development of novel therapeutic agents that have significantly improved overall survival, multiple myeloma remains an incurable disease. Matrix metalloproteinase-2 (MMP-2) is associated with c...
1
Treatment of pediatric femoral shaft fractures by stainless steel and titanium elastic nail system: A randomized comparative trial
Pediatric Diaphyseal Femur Fractures 2020 Review
PURPOSE: Literature suggests that the lower modulus of elasticity of titanium makes it ideal for use in children compared with stainless steel. Better fracture stability was observed in association with titanium nails on torsional and axial compression testing. However, stainless steel nails are stiffer than titanium c...
0
Hemorrhagic-acquired factor XIII deficiency associated with tocilizumab for treatment of rheumatoid arthritis
PJI DX Updated Search
Factor XIII (FXIII) is the final enzyme in the coagulation cascade. Acquired
0
Targeting p38 MAPK for the treatment of inflammatory arthritis
MSTS 2018 - Femur Mets and MM
Inflammatory bone destruction is a relatively frequent and incapacitating complication of rheumatoid arthritis and other chronic inflammatory joint diseases, and is a product of acceleratesd osteoclast recruitment and activation in bone under the aegis of cytokines produced in the inflammatory milieu. Over the past dec...
0
Assessment of effects of ultrasound therapy on reduction of pain in gonarthrosis
OAK 3 - Non-arthroplasty tx of OAK
AIM: To examine the effects of sonotherapy on the activities of daily living or as well as the reduction of pain in gonarthrosis. METHODS: A retrospective- prospective clinical study included 63 patients, 47 to 86 years old with a verified diagnosis of gonarthrosis. Subjects were divided into two groups. The first grou...
1
Knee extensor strength gains mediate symptom improvement in knee osteoarthritis: secondary analysis of a randomised controlled trial
OAK 3 - Non-arthroplasty tx of OAK
OBJECTIVE: To determine if an increase in knee extensor strength mediates the effect of a 12-week knee extensor strength training program on pain and physical function improvement in people with knee osteoarthritis (OA). DESIGN: Secondary analysis from a randomised controlled trial comparing the effects of a 12-week kn...
0
Do facet joint capsular ligaments contain estrogen receptors? Application to pathogenesis of degenerative spondylolisthesis
Glenohumeral Joint OA
Studies showing that degenerative spondylolisthesis is 4 to 5 times more common in females than in males have suggested that hormonal influences account for this gender difference. Estrogen has been shown to play a role in other instabilities, such as those of the anterior cruciate ligament and the shoulder capsular li...
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Chronic joint pain in the lower body is associated with gait differences independent from radiographic osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
Gait is an important indicator of health. Chronic lower body pain may impair gait and lead to morbidity and mortality. We investigated the associations between lower body pain and gait in community-dwelling individuals, independent from osteoarthritis (OA). This population based cohort study included 2304 Rotterdam Stu...
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Reading performance and central field loss
Upper Eyelid and Brow Surgery
Age-related macular degeneration is a major cause of blindness in Europe and the U.S. and a leading cause of significant loss of visual acuity in elderly patients. Reading is a key visual task in everyday living involving a synthesis of a number of different motor, sensory and cognitive functions. When the centre of a ...
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Role of psychosocial stress in recovery from common whiplash
DoD PRF (Psychosocial RF)
It is widely accepted that psychosocial factors are related to illness behaviour and there is some evidence that they may influence the rate of recovery from post-traumatic disorders. The abilities of psychosocial stress, somatic symptoms, and subjectively assessed cognitive impairment to predict delayed recovery from ...
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Fresh and frozen articular cartilage allografts
Diagnosis and Treatment of Osteochondritis Dissecans AUC
Fresh and frozen cartilage allografts both function well to relieve joint pain due to cartilage injury. Fresh cartilage allografts appear to remain alive for many months and are most applicable to small injuries such as osteochondritis dissecans, traumatic defects, and osteonecrosis. Frozen cartilage allografts have be...
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Clinical outcomes of suture delay in forehead flap
Reconstruction After Skin Cancer
The delay phenomenon is a surgical procedure performed to raise a wider skin flap and to improve the survival of skin flaps. Surgery, chemicals, sutures, and lasers can be used for the delay procedure. In this study, delayed forehead flaps created by suturing were used for coverage of nasal skin defects in eleven patie...
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Hip Resurfacing Using Highly Cross-linked Polyethylene: Prospective Study Results at 8.5 Years
Hip Fx in the Elderly 2019
BACKGROUND: Hip resurfacing is an option to consider when treating younger, more active patients. Advantages over total hip arthroplasty include a more normal gait and a lower incidence of thigh pain. METHODS: In this prospective study, 190 hip resurfacing procedures (164 participants) were performed using a cobalt-chr...
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Scarred muscle excision for the treatment of established ischemic contracture of the lower extremity
DOD - Acute Comp Syndrome CPG
Nine patients with rigid equinocavovarus contractures of the foot and ankle after ischemic episodes of the leg were treated from 1986 to 1989. The ischemic contractures occurred after tibial and fibular fractures in six cases, and after a trimalleolar ankle fracture, an electrical burn, and cardiac bypass surgery in on...
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Antibiotic bone cement for the treatment of Pseudomonas aeruginosa in joint arthroplasty: comparison of tobramycin and gentamicin-loaded cements
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
One hundred clinical isolates of Pseudomonas aeruginosa were collected from 22 medical centers throughout Europe and were challenged with two aminoglycoside-loaded bone cements, employing a modified in vitro Kirby-Bauer susceptibility model. The results of this study show that Simplex P with tobramycin exhibits antibac...
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Social support contributes to outcomes following distal radius fractures
Distal Radius Fractures
Background. Distal radius fractures are the most common fracture of the upper extremity and cause variable disability. This study examined the role of social support in patient-reported pain and disability at one year following distal radius fracture. Methods. The Medical Outcomes Study Social Support Survey was admini...
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Large-volume liposuction and extensive abdominoplasty: a feasible alternative for improving body shape
Reduction Mammoplasty for Female Breast Hypertrophy
Forty-two female patients underwent liposuction of large volumes and extensive abdominoplasty during an 18-month period, with an average follow-up period of 9 months. Fifty-two percent of the patients underwent a third surgical procedure, which was basically aesthetic. The average age was 40 years; weight varied betwee...
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Can an injured discoid lateral meniscus be returned to the correct anatomic position and size of the native lateral meniscus after surgery?
AMP (Acute Meniscal Pathology)
BACKGROUND: No previous studies have compared the position and size of the remaining discoid lateral meniscus (DLM) with that of a normal lateral meniscus. This study aimed to evaluate the postoperative position and size of DLM compared with that of normal controls using magnetic resonance imaging (MRI). METHODS: This ...
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Hereditary multiple exostoses of the hip
Osteochondritis Dissecans 2020 Review
PURPOSE: To assess the radiographic features of 36 hips with hereditary multiple exostoses (HME). METHODS: Hip parameters of 12 males and 6 females (36 hips) aged 2 to 28 years with HME were assessed using anteroposterior radiographs. The recorded features included the sites of osteochondromas, the femoral head/neck ra...
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Surgery of Cosmetic sequelae after breast-conserving therapy
Reduction Mammoplasty for Female Breast Hypertrophy
Although a considerable number of patients have an unfair cosmetic result after breast-conserving therapy, which correlates with poor psychosocial functioning, surprisingly, really only very few patients undergo surgical correction. The purpose of this article was to report our experience in the surgical treatment of s...
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Octamethylcyclotetrasiloxane (D4)
Reduction Mammoplasty for Female Breast Hypertrophy
Octamethylcyclotetrasiloxane (D4; CAS No. 556-67-2) is used as a monomer in the manufacture of polymeric materials, which are widely used in various industrial and/or medical applications, such as breast implants. D4 has a relatively low order of toxicity following acute administration via the oral, dermal, and inhalat...
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Interventions for increasing ankle range of motion in patients with neuromuscular disease
Management of Hip Fractures in the Elderly
BACKGROUND: Reduced ankle dorsiflexion range of motion, or ankle equinus, is a common and disabling problem for patients with neuromuscular disease. Clinicians devote considerable time and resources implementing interventions to correct this problem although few of these interventions have been subject to rigorous empi...
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Incidence of acute care adverse events and long-term health-related quality of life in patients with TSCI
DoD PRF (Psychosocial RF)
Background context: Adverse events (AEs) with significant resultant morbidity are common during the acute hospital care of patients with traumatic spinal cord injury (TSCI). The Rick Hansen SCI Registry (RHSCIR) collects Canada-wide data on patients with TSCI, such as sociodemographic, injury, diagnosis, intervention, ...
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Intrathecal Diamorphine Versus Femoral Nerve Block in Primary Total Knee Arthroplasty
OAK 3 - Non-arthroplasty tx of OAK
In 2008, the Prospect Working Group, a multidisciplinary expert panel, published their consensus guidelines on the relative merits of different anaesthetic and analgesic techniques for TKA based on a review of the available published literature up to 2005. These guidelines supported the use of general anaesthesia combi...
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Knee arthroscopy with the use of local anesthesia--an increased risk for repeat arthroscopy? A prospective, randomized study with a six-month follow-up
Surgical Management of Osteoarthritis of the Knee CPG
Although there have been many reports of good results when local anesthesia is used with knee arthroscopy, it is not used as a standard anesthetic. Concerns about local anesthesia include the fear of prolonged surgery, which could result in inadequate anesthesia, thus causing the patient unnecessary discomfort. The pur...
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In vivo models of multiple myeloma (MM)
MSTS 2018 - Femur Mets and MM
The development of the plasma cell tumor (PCT) model was the first widely accepted in vivo model of multiple myeloma (MM). Potter and colleagues used this chemically induced PCT model to study the pathophysiology of malignant plasma cells and also used it to screen anti-MM agents. Two decades later the C57BL/KaLwRij mo...
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Low haemoglobin at admission is associated with mortality after hip fractures in elderly patients
Hip Fx in the Elderly 2019
AIMS: Low haemoglobin (Hb) at admission has been identified as a risk factor for mortality for elderly patients with hip fractures in some studies. However, this remains controversial. This study aims to analyze the association between Hb level at admission and mortality in elderly patients with hip fracture undergoing...