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0 | Osteochondral allograft transplantation in the knee | Diagnosis and Treatment of Osteochondritis Dissecans AUC | Fresh osteochondral allograft (OCA) transplantation has over a 100-year clinical history. Many clinical and basic scientific studies have been performed with the result that allografting is now a part of the "cartilage repair paradigm" for the treatment of chondral or osteochondral lesions. In the knee joint, allograft... |
0 | Rheumatology in India - Quo vadis? | OAK 3 - Non-arthroplasty tx of OAK | Rheumatology has been a neglected subspecialty in India. A staggering patient load, a severely inadequate number of trained rheumatology specialists, therapeutic nihilism and limited advocacy are some of the critical challenges that confront rheumatology care, and possibly explain the high rates of reliance on compleme... |
0 | Young Adult Hip: Reactivation of dormant, previously undiagnosed Mycobacterium Tuberculosis infection following intra-articular steroid injection | PJI DX Updated Search | INTRODUCTION: Tuberculosis (TB) still remains a common problem in the UK and, with the increasing number of patients being offered arthroplasties; periprosthetic involvement is not uncommon anymore. However, the diagnosis of TB infected arthroplasties still remains difficult and misdiagnosis is common, therefore delayi... |
0 | Allograft bone in two-stage revision of the hip for infection? | Management of Hip Fractures in the Elderly | A two-stage procedure was carried out on 57 patients with confirmed infection in a hip replacement. Allograft bone was used in the second stage. Pathogenic organisms were identified in all patients. In stage 1, the prosthesis was removed together with infected tissue. Antibiotics were added to customised cement beads. ... |
0 | Utility of Postoperative Antibiotics After Percutaneous Pinning of Pediatric Supracondylar Humerus Fractures | DoD SSI (Surgical Site Infections) | BACKGROUND: Pediatric supracondylar humerus fractures are common injuries that are often treated surgically with closed reduction and percutaneous pinning. Although surgical-site infections are rare, postoperative antibiotics are frequently administered without evidence or guidelines for their use. With the increasing ... |
1 | The In-Hospital Length of Stay after Hip Fracture in Octogenarians: Do Delirium and Dementia Shape a New Care Process? | Hip Fx in the Elderly 2019 | BACKGROUND: Hip fracture is a major health problem and a patient's biological age, comorbidity, and cognitive vulnerability have an impact on its related outcomes. Length of stay (LOS) for these highly vulnerable patients is rather long and the possible causes have not been clearly identified yet.
OBJECTIVE: We aimed t... |
0 | Timed "up & go" test as a predictor of falls within 6 months after hip fracture surgery | Hip Fx Time to Surgery | BACKGROUND AND PURPOSE: Previous studies of Timed "Up & Go" Test (TUG) scores as a predictor of falls were based primarily on retrospective data, and no prospective studies of the TUG for predicting falls in people with hip fracture are available. The purpose of this study was to determine whether TUG scores obtained u... |
0 | The Use of Cement in Hip Arthroplasty: A Contemporary Perspective | Hip Fx in the Elderly 2019 | Notable advances in hip arthroplasty implants and techniques over the past 60 years have yielded excellent survivorship of fully cemented, hybrid, and reverse hybrid total hip replacements as demonstrated in joint registries worldwide. Major advances in noncemented implants have reduced the use of cement, particularly ... |
0 | Protein and energy balance following femoral neck fracture in geriatric patients | Management of Hip Fractures in the Elderly | To elucidate the effect of total peripheral parenteral nutrition (TPPN) on protein kinetics following injury, we compared the whole-body leucine kinetic response using a primed-constant infusion of L-[1-14C]leucine in 33 elderly patients (aged 82 +/- 1.0 years) following hip fracture and 33 healthy elderly control subj... |
0 | Relationship between clinical outcomes and Dutch frailty score among elderly patients who underwent surgery for hip fracture | Hip Fx in the Elderly 2019 | Background: Frailty is a geriatric condition that is associated with an increased risk of mortality and functional decline. To date, mainly the Groningen Frailty Indicator (GFI) and Hospital Safety Management (VeiligheidsManagementSysteem [VMS]) frailty score are used to determine frailty in several hospitals in the Ne... |
0 | Medical dental prophylaxis of endocarditis | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | Antibiotics have long been the main reason for the increase in man's longevity. Since their discovery, man has tried to reduce the level of infection by treating with antibiotics. At the same time, prophylactic use has been suggested, although this is controversial. Their routine use is not recommended, and empirical t... |
1 | Femoral nerve block for total knee replacement - a word of caution | Surgical Management of Osteoarthritis of the Knee CPG | Femoral nerve block (FNB) is a well documented option for post-operative analgesia following major knee surgery. However, motor blockade may be prolonged preventing early mobilisation thereby increasing the length of stay. In addition, as a consequence of persistent quadriceps weakness, patients have an increased risk ... |
1 | Spinal narcotics for postoperative analgesia in total joint arthroplasty. A prospective study | Surgical Management of Osteoarthritis of the Knee CPG | Sixty patients who were scheduled to have an elective total hip or knee arthroplasty were randomly assigned to one of three groups of twenty patients each before operation with spinal anesthesia. A double-blind technique was used throughout the study. The patients in Group I (control group) received hyperbaric 1 per ce... |
0 | Viscosupplementation: Techniques, indications, results | OAK Recommendation 9 Articles | Viscosupplementation by hyaluronic acid (HA) injections is frequently used for local treatment of osteoarthritis (OA), due to ease of use and good tolerance. A profusion of linear or reticulated HA derivates are marketed, with varied characters and levels of evidence. Viscosupplementation has demonstrated moderate but ... |
1 | Small anteroposterior inclination of the acromion is a predictor for posterior glenohumeral erosion (B2 or C) | Glenohumeral Joint OA | BACKGROUND: Anatomic factors associated with static posterior translation of the humeral head with or without glenohumeral osteoarthritis are unknown. We tested the hypothesis that there is an association between glenoid wear, glenoid version, and/or anteroposterior acromial tilt.
METHODS: Ninety-nine patients with gle... |
0 | The characteristics and neuronal substrate of saccadic eye movement plasticity | Upper Eyelid and Brow Surgery | Saccadic eye movements are shifts in the direction of gaze that rapidly and accurately aim the fovea at targets of interest. Saccades are so brief that visual feedback cannot guide them to their targets. Therefore, the saccadic motor command must be accurately specified in advance of the movement and continually modifi... |
0 | Effects of perioperative administration of a selective cyclooxygenase 2 inhibitor on pain management and recovery of function after knee replacement: a randomized controlled trial | Surgical Management of Osteoarthritis of the Knee CPG | CONTEXT: Controlling postoperative pain after knee replacement while reducing opioid-induced adverse effects and improving outcomes remains an important challenge. OBJECTIVE: To assess the effect of combined preoperative and postoperative administration of a selective inhibitor of cyclooxygenase 2 on opioid consumption... |
0 | Upper limb nerve entrapments in elite wheelchair racers | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | The prevalence of upper limb nerve injuries has been reported to be as high as 73% in individuals who rely on manual wheelchairs for mobility. Many authors hypothesize that the repetitive trauma to carpal canal structures caused by propelling a wheelchair is the reason for this high prevalence. The purpose of this stud... |
0 | Safety and efficacy of vertebroplasty for acute painful osteoporotic fractures (VAPOUR): a multicentre, randomised, double-blind, placebo-controlled trial | Pediatric Supracondylar Humerus Fracture 2020 Review | Background We hypothesised that vertebroplasty provides effective analgesia for patients with poorly controlled pain and osteoporotic spinal fractures of less than 6 weeks' duration. The effectiveness of vertebroplasty, using an adequate vertebral fill technique, in fractures of less than 6 weeks' duration has not been... |
0 | Incidence and risk factors of bisphosphonate-related osteonecrosis of the jaw in multiple myeloma patients having undergone autologous stem cell transplantation | MSTS 2018 - Femur Mets and MM | BACKGROUND: Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a severe complication of bisphosphonate therapy. Due to their long survival and subsequently high cumulative doses of bisphosphonates, multiple myeloma patients have the highest risk of developing BRONJ of all patients treated with bisphosphonates. ... |
0 | Underreduced supracondylar fracture of the humerus in children: clinical significance at skeletal maturity | The Treatment of Pediatric Supracondylar Humerus Fractures AUC | BACKGROUND: Although supracondylar fractures of the humerus in children are common, the literature is sparse regarding acceptable limits of reduction of these fractures in the sagittal plane. METHODS: We retrospectively reviewed 223 pediatric cases of supracondylar fractures of the elbow treated in our hospital between... |
0 | Assessment of the curative effects of open reduction and internal fixation with bone grafting on calcaneal displaced intra-articular fractures | DoD SSI (Surgical Site Infections) | Objective: The aim of this study was to compare the curative effects between open reduction and internal fixation with bone grafting and non-surgical treatment of calcaneal displaced intra-articular fractures. Methods: Data concerning 113 patients with closed calcaneal fractures, treated in Dongying People’s Hospital f... |
0 | Long-term results of breast reduction in female-to-male transsexuals | Reduction Mammoplasty for Female Breast Hypertrophy | UNLABELLED: Transsexualism is considered to be an extreme end in a large group of gender identity disorders. Two main types of transsexualism are identified: male-to-female (MtF) and female-to-male (FtM). Transsexual persons have a feeling of being incarcerated in a foreign body and therefore they wish to change their ... |
1 | Fate of the ulnar nerve after operative fixation of distal humerus fractures | Pediatric Supracondylar Humerus Fracture 2020 Review | Objectives: It is well recognized that operative treatment of a fracture of the distal humerus requires handling of the ulnar nerve, which can cause nerve dysfunction; however, the incidence of postoperative ulnar nerve dysfunction is not well studied. Our purpose was to determine the incidence of ulnar nerve dysfuncti... |
0 | Comparison study of small splint fixation and plaster slab fixation for the treatment of distal radius fractures | Distal Radius Fractures | OBJECTIVE: To study the advantage of fir bark splint for the treatmet of distal radius fracture. METHODS: From January 2006 to June 2008, 80 cases were randomly divided into two groups and treated by fir bark splint fixation or plaster fixation. There were 40 cases in the fir bark splint group, including 18 males and 2... |
1 | Prediction of range of motion 2 years after mobile-bearing total knee arthroplasty: PCL-retaining versus PCL-sacrificing | Surgical Management of Osteoarthritis of the Knee CPG | PURPOSE: This study evaluated the changes in the range of motion (ROM) with time postoperatively. METHOD: The pre- and intraoperative ROM was compared with the ROM 3, 6, 12, and 24 months postoperatively to clarify the effects of posterior cruciate ligament-retaining (PCLR) and posterior cruciate ligament-sacrificing (... |
0 | Long-term follow-up on patients treated for abdominal fat using a selective contactless radiofrequency device | Panniculectomy & Abdominoplasty CPG | BACKGROUND AND OBJECTIVE: The aim of this study was to evaluate how abdominal circumferential reduction achieved after using a noninvasive radiofrequency device (BTL Vanquish, BTL Industries Inc., Boston, MA) evolves over a 4-year period. METHODS: This is a follow-up on patients who were treated in our practice for abd... |
0 | Combined popliteal and saphenous nerve blocks at the knee: an underused alternative to general or spinal anesthesia for foot and ankle surgery | Surgical Management of Osteoarthritis of the Knee CPG | Peripheral nerve blocks at the ankle have long been used for foot surgery. However, when local foot and ankle blocks are inappropriate or contraindicated, general and spinal anesthesia are the common alternatives. Both have disadvantages and require added equipment and monitors. Combined popliteal and saphenous nerve b... |
0 | Outdoor dynamic subject-specific evaluation of internal stresses in the residual limb: hydraulic energy-stored prosthetic foot compared to conventional energy-stored prosthetic feet | DoD LSA (Limb Salvage vs Amputation) | The prosthetic foot plays an important role in propelling, breaking, balancing and supporting body loads while the amputee ambulates on different grounds. It is therefore important to quantify the effect of the prosthetic foot mechanism on biomechanical parameters, in order to prevent pressure ulcers and deep tissue in... |
0 | Exercise compliance among patients with multiple myeloma undergoing chemotherapy: a retrospective study | MSTS 2022 - Metastatic Disease of the Humerus | Purpose: Multiple myeloma (MM) is often associated with osteolytic bone disease and anemia, resulting in skeletal fragility and persistent fatigue, pain, and reduced quality of life. Exercise is considered safe and beneficial for this population. Our objectives were to evaluate the extent to which MM patients undergoin... |
0 | Allele frequency of the G -> T mutation of teh Co/1A1 gene analyzed by an | Management of Hip Fractures in the Elderly | The allele frequency of the G->T mutation of COL1A1 gene (collagen type I (alpha) 1 gene, GenBank accession n. AF017178) was analyzed by a new |
1 | Revision total knee arthroplasty with a cemented posterior stabilized, condylar constrained or fully constrained prosthesis: a minimum 2-year follow-up analysis | Surgical Management of Osteoarthritis of the Knee CPG | BACKGROUND: The clinical and radiological outcomes of revision total knee arthroplasty with a cemented posterior stabilized (PS), condylar constrained knee (CCK) or a fully constrained rotating hinge knee (RHK) prosthesis were evaluated. METHODS: This study reviewed the clinical and radiological results of 36 revision ... |
0 | A unique cause of a rare disorder, unilateral macromastia due to lymphangiomatosis of the breast: a case report | Reduction Mammoplasty for Female Breast Hypertrophy | Macromastia and in particular unilateral macromastia is a rare clinical entity. It relates to massive enlargement of the breast in non-obese women. This case report describes an initially mild unilateral asymmetry occurring nine months postpartum in a 33-year-old female. However, following her second pregnancy within 1... |
0 | Causes of Missed Referrals to Low-Vision Rehabilitation Services: Causes in a Tertiary Eye Care Setting | Upper Eyelid and Brow Surgery | PURPOSE: To identify the referral pattern and identify causes of missed referrals to low-vision services in a tertiary eye care center. METHODS: A retrospective review of all the hospital records of patients seen from September-December 2012 was done to identify patients with visual impairment. Low vision was defined a... |
0 | Results of non-operative treatment of fractures of the glenoid fossa | Glenohumeral Joint OA | AIMS: Our aim was to investigate the outcomes of patients with a displaced fracture of the glenoid fossa who are treated conservatively. There is little information in the literature about the treatment of these rare injuries non-operatively.
PATIENTS AND METHODS: We reviewed 24 patients with a mean age of 52 years (19... |
0 | [Clinical effects of comprehensive rehabilitation after minimally invasive total hip arthroplasty] | Management of Hip Fractures in the Elderly | OBJECTIVE: To explore clinical effects of comprehensive rehabilitation therapy for function restore of hip joint after minimally invasive total hip arthroplasty.METHODS: From March 2006 to February 2008, 100 patients were randomly divided into the treatment group and the control group. Fifty patients in the treatment g... |
0 | Efficacy of intra-articular polynucleotides in the treatment of knee osteoarthritis: a randomized, double-blind clinical trial | OAK 3 - Non-arthroplasty tx of OAK | This randomized, doubleâ?blind clinical trial was conducted over 16 weeks to assess the efficacy and safety profile of intraâ?articular polynucleotides gel injections in the treatment of knee osteoarthritis associated with persistent knee pain. 60 patients were enrolled and randomized to receive intraâ?articular pol... |
0 | 5 versus 10 days of treatment with ceftriaxone for bacterial meningitis in children: a double-blind randomised equivalence study | Patrick’s pharmacoepidemiology project | BACKGROUND: Bacterial meningitis is an important cause of morbidity and mortality in developing countries, but the duration of treatment is not well established. We aimed to compare the efficacy of 5 and 10 days of parenteral ceftriaxone for the treatment of bacterial meningitis in children. METHODS: We did a multicoun... |
0 | Utility of somatosensory evoked potentials in chronic acquired demyelinating neuropathy | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Chronic acquired demyelinating polyneuropathy (CADP) is a heterogeneous syndrome that may be classified into a number of subtypes. Somatosensory evoked potentials (SSEPs) assess proximal segments of sensory nerves, inadequately assessed by routine nerve conduction studies (NCSs). The aim of the present study was to det... |
0 | Hospitalizations for hip fractures among elderly persons in Hawaii, 1986-1990 | Management of Hip Fractures in the Elderly | Hawaii differs ethnically, geographically, and culturally from other states; therefore, United States hip fracture data cannot be assumed to apply to Hawaii. The purpose of this research was to gain new knowledge about hip fracture in Hawaii to plan and target appropriate services and design preventive measures. Peer R... |
0 | Hyaluronic acid injections for knee osteoarthritis. Systematic review of the literature | AAHKS (4) Acetaminophen | Objective. To determine whether viscosupplementation with intra-articular hyaluronic acid (HA) injections improves pain and function in patients with osteoarthritis (OA) in their knees. Data Sources. We searched MEDLINE, Pre-MEDLINE, and Cochrane databases using the MeSH headings and key words osteoarthritis (knee) and... |
0 | Weak associations between body mass index and self-reported disability in people with unilateral anterior cruciate ligament reconstruction | OAK 3 - Non-arthroplasty tx of OAK | PURPOSE AND HYPOTHESIS: Individuals with an anterior cruciate ligament reconstruction (ACLR) are susceptible to persistent disability, weight gain and the development of knee osteoarthritis. It remains unclear whether body mass index (BMI) is a factor that influences disability following ACLR. The purpose of this study... |
0 | Physiotherapists' experiences of the management of anterior cruciate ligament injuries | DoD PRF (Psychosocial RF) | BACKGROUND: While extensive research has been reported for management of anterior cruciate ligament (ACL) injuries, variation in treatment by physiotherapists is evident.
OBJECTIVES: To explore physiotherapists' experiences regarding ACL injury rehabilitation and factors that influenced physiotherapists' decision makin... |
0 | Coonrad-Morrey total elbow arthroplasty for tumours of the distal humerus and elbow | MSTS 2022 - Metastatic Disease of the Humerus | We reviewed 20 patients who had undergone a Coonrad-Morrey total elbow arthroplasty after resection of a primary or metastatic tumour from the elbow or distal humerus between 1980 and 2002. Eighteen patients underwent reconstruction for palliative treatment with restoration of function after intralesional surgery and t... |
0 | Charcot shoulder and elbow: a review of the literature and update on treatment | Pediatric Supracondylar Humerus Fracture 2020 Review | Charcot arthropathy of the shoulder and elbow is a rare disease process initially described in the 1700s; however, it was not until the 19th century that physicians understood its association with other disease processes such as cervical spine pathology and diabetes. A primary complaint is painful or painless joint dys... |
1 | What Factors are Predictive of Patient-reported Outcomes? A Prospective Study of 337 Shoulder Arthroplasties | Glenohumeral Joint OA | Background: Although shoulder arthroplasties generally are effective in improving patientsâ?? comfort and function, the results are variable for reasons that are not well understood. Questions/Purposes: We posed two questions: (1) What factors are associated with better 2-year outcomes after shoulder arthroplasty? (2) ... |
0 | Two-Stage Primary Arthroplasty of Native Hips and Knees That Had Previously Failed Treatment for Septic Arthritis: A Single-Center Experience | DoD SSI (Surgical Site Infections) | Background: Patients with a history of degenerative joint disease secondary to an acute or remote episode of septic arthritis of the native knee or hip present a unique challenge for the orthopaedic surgeon. This study describes our experience with two-stage primary arthroplasty for such patients. Methods: We reviewed ... |
1 | The knee meniscus: structure-function, pathophysiology, current repair techniques, and prospects for regeneration | AMP (Acute Meniscal Pathology) | Extensive scientific investigations in recent decades have established the anatomical, biomechanical, and functional importance that the meniscus holds within the knee joint. As a vital part of the joint, it acts to prevent the deterioration and degeneration of articular cartilage, and the onset and development of oste... |
0 | Psychological and physiological responses following repeated peer death | DoD PRF (Psychosocial RF) | OBJECTIVE: Undergraduates at a university in the United States were exposed - directly and indirectly - to 14 peer deaths during one academic year. We examined how individual and social factors were associated with psychological (e.g., anxiety, depression, somatization) and physiological (i.e., cortisol) distress respo... |
1 | Anesthesia for Same-Day Total Joint Replacement | AAHKS (9/10) Regional Nerve Blocks | Demand for low-cost, high-quality health care has forced the total joint replacement (TJR)industry to evaluate and mitigate high variable costs. Minimizing hospital stay can significantly reduce total cost of care. A shortened hospital stay does not compromise patient safety or satisfaction, and may reduce perioperativ... |
0 | Epicanthoplasty with modified Y-V advancement procedure | Upper Eyelid and Brow Surgery | The presence of epicanthal folds and lack of supratarsal folds are unique features in most Asian eyelids. Although many surgical procedures are available to eliminate epicanthal folds, scarring on the medial canthus is still an obstacle for surgeons to overcome. From January of 1989 to November of 1997, we used modifie... |
0 | Effects of high-intensity strength training on multiple risk factors for osteoporotic fractures. A randomized controlled trial | Management of Hip Fractures in the Elderly | OBJECTIVE: To determine how multiple risk factors for osteoporotic fractures could be modified by high-intensity strength training exercises in postmenopausal women. DESIGN: Randomized controlled trial of 1-year duration. SETTING: Exercise laboratory at Tufts University, Boston, Mass. POPULATION: Forty postmenopausal w... |
0 | Revision of the Sheehan total knee arthroplasty | Surgical Management of Osteoarthritis of the Knee CPG | The use of the Sheehan knee prosthesis extended from 1971 to 2002. It incorporated a semi-constrained hinge with intra-medullary stems cemented into the femur and tibia. While some authors have reported excellent short-term results, others have reported revision rates of up to 31% at 5--10 years. The aim of this study ... |
0 | Outcome after hemi-arthroplasty for displaced intracapsular femoral neck fracture related to mental state | DoD SSI (Surgical Site Infections) | This study was performed to assess mortality and functional outcome after hemi-arthroplasty for displaced intracapsular femoral neck fractures in relation to mental state. Between 1991 and 1995, 202 consecutive patients over 70 years of age were followed for at least two years or until death. Thirty-nine patients were ... |
0 | Hepatocyte growth factor enhances CXCR4 expression favoring breast cancer cell invasiveness | MSTS 2018 - Femur Mets and MM | Microenvironmental factors affect different aspects of tumor cell biology, including cell survival, invasion, and metastasis. Here, we report that hepatocyte growth factor and hypoxia may contribute to breast carcinoma cell invasiveness by inducing the chemokine receptor CXCR4. Hepatocyte growth factor enhanced CXCR4 m... |
0 | Acral necrotizing mycosis fungoides | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | A 65-year-old male with long-standing acral "eczema" and patches of mycosis fungoides suddenly developed a transformed, necrotizing ulcerative cutaneous T-cell lymphoma manifesting as necrotic lesions of the toe and lip. The tumor had brown and/or black eschars on the surface and grew multiple opportunistic organisms. ... |
0 | Impact of a child's cancer disease on parents' everyday life: a longitudinal study from Sweden | DoD PRF (Psychosocial RF) | BACKGROUND: A child's cancer disease may disrupt the daily life of the affected family for a long period. The aim was to describe restrictions on parents' leisure activities and work/studies during and after the child's treatment.
METHODS: This study used data from a cohort of mothers and fathers (n=246) of children di... |
0 | Thiazide diuretics and the risk for hip fracture | Management of Hip Fractures in the Elderly | BACKGROUND: Since most hip fractures are related to osteoporosis, treating accelerated bone loss can be an important strategy to prevent hip fractures. Thiazides have been associated with reduced age-related bone loss by decreasing urinary calcium excretion. OBJECTIVE: To examine the association between dose and durati... |
0 | Continuous Femoral Nerve Block in Total Knee Arthroplasty: Immediate and Two-Year Outcomes | AAHKS (8) Anesthetic Infiltration | We conducted a prospective study to investigate the immediate and 2-year outcomes of total knee arthroplasty patients who received continuous femoral nerve block (FNB) for analgesia. Sixty patients undergoing unilateral total knee arthroplasty were randomized into 3 groups and received high-dose continuous FNB, low-dos... |
0 | Effect of Body Weight-Supported Exercise on Symptoms of Knee Osteoarthritis: A Follow-up Investigation | OAK 3 - Non-arthroplasty tx of OAK | OBJECTIVE: To examine the long-term effect of participation in a 12-week lower-body positive pressure (LBPP)-supported low-load treadmill exercise regime on knee joint pain, physical function, and thigh muscle strength in patients with knee osteoarthritis (OA).
DESIGN: Prospective, observational, repeated measures.
SET... |
0 | Treatment of advanced medullary thyroid carcinoma with a combination of recombinant interferon alpha-2b and octreotide | MSTS 2018 - Femur Mets and MM | BACKGROUND: The medical treatment of advanced medullary thyroid carcinoma (MTC) is still questionable. Results of chemotherapy are disappointing with almost no curative responses, few partial responses, and many side-effects. A recent report has suggested the activity of combination recombinant interferon alpha-2b (rIF... |
0 | Cartilage oligomeric matrix protein levels in synovial fluid in patients with primary knee osteoarthritis and healthy controls: A preliminary comparative analysis with serum cartilage oligomeric matrix protein | OAK 3 - Non-arthroplasty tx of OAK | Objectives: This study aims (i) to compare synovial fluid and serum cartilage oligomeric matrix protein levels in patients with primary knee osteoarthritis and healthy controls, (ii) compare variations of synovial fluid and serum cartilage oligomeric matrix protein levels according to sex, Kellgren-Lawrence grades, and... |
0 | Multi-drug therapy in chronic condition multimorbidity: a systematic review | SR for PM on OA of All Extremities | BACKGROUND: Older populations often suffer from multimorbidity and guidelines for each condition are often associated with recommended drug therapy management. Yet, how different and specific multimorbidity is associated with number and type of multi-drug therapies in general populations is unknown. AIM: The aim of thi... |
0 | Fracture risk in patients with prostate cancer on androgen deprivation therapy | Management of Hip Fractures in the Elderly | Although a decrease in bone mass is a well-known side effect of hormone therapy for prostate carcinoma, its clinical significance is unclear, as there is only scanty information about the incidence of fractures. Therefore, the aim of this study was to determine the risk of non-metastatic fractures in patients with pros... |
1 | Predicting the future development of depression or PTSD after injury | DoD PRF (Psychosocial RF) | Objective: The objective was to develop a predictive screener that when given soon after injury will accurately differentiate those who will later develop depression or posttraumatic stress disorder (PTSD) from those who will not. Method: This study used a prospective, longitudinal cohort design. Subjects were randomly... |
0 | Inappropriate prescribing in geriatric patients | Management of Hip Fractures in the Elderly | Inappropriate prescribing in older people is a common condition associated with significant morbidity, mortality, and financial costs. Medication use increases with age, and this, in conjunction with an increasing disease burden, is associated with adverse drug reactions. This review outlines why older people are more ... |
0 | Longitudinal comparison of visual acuity as measured by the ETDRS chart and by the potential acuity meter in eyes with macular edema, and its relationship with retinal thickness and sensitivity | Upper Eyelid and Brow Surgery | PURPOSE: To evaluate the relationship between visual acuity as measured by the Early Treatment Diabetic Retinopathy Study (ETDRS) chart and by the potential acuity meter (PAM) with retinal thickness and sensitivity measured by a combined microperimetry/optical coherence tomography system (OCT). METHODS: Forty-four pati... |
0 | Imaging of radial wrist pain. Part II: Pathology | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Pain on the radial side of the wrist is a common clinical presentation. Such wrist pain may provide a diagnostic challenge for radiologists, in view of the small size of the anatomic structures, the occasional subtlety of the imaging findings, the diversity of potential etiologies, as well as the non-infrequent occurre... |
0 | Lower-limb asymmetries in early and late middle age | Management of Hip Fractures in the Elderly | The present study examined the relationship between upper- and lower-limb laterality and the difference in kinaesthetic function between lower limbs. A total of 360 early and late middle-aged people from rural areas in Japan participated in the study. The first purpose was to describe upper- and lower-limb lateral pref... |
1 | Long-term pamidronate treatment of advanced multiple myeloma patients reduces skeletal events. Myeloma Aredia Study Group | MSTS 2018 - Femur Mets and MM | PURPOSE: To determine the efficacy and safety of 21 monthly cycles of pamidronate therapy in patients with advanced multiple myeloma.
PATIENTS AND METHODS: Patients with stage III myeloma and at least one lytic lesion received either placebo or pamidronate 90 mg intravenously administered as a 4-hour infusion monthly f... |
0 | The Heart in COVID19: Primary Target or Secondary Bystander? | Coronavirus Disease 2019 (COVID-19) | In the throes of the current COVID-19 pandemic, interest has burgeoned in the cardiovascular complications of this virulent viral infection. As troponin, a biomarker of cardiac injury, often rises in hospitalized patients, its interpretation and actionability require careful consideration. Fulminant myocarditis due to ... |
0 | Iatrogenic Injuries of the Palmar Branch of the Median Nerve Following Volar Plate Fixation of the Distal Radius | DoD SSI (Surgical Site Infections) | BACKGROUND: Our aims were to identify iatrogenous injuries to the palmar branch of the median nerve sustained during volar plate fixation of the distal radius, make the clinician aware of this relatively uncommon complication of distal radius fixation, to emphasise common threads in symptomatology and to propose an alg... |
0 | Raloxifene: A review of its use in postmenopausal osteoporosis | AAHKS (2) Corticosteroids | Raloxifene is a selective estrogen receptor modulator that partially mimics the effects of estrogens in bone and the cardiovascular system, while functioning as an antiestrogen in endometrial and breast tissue. In randomised placebo-controlled studies involving postmenopausal women or patients with osteoporosis, raloxi... |
0 | Distribution of coronoid fracture lines by specific patterns of traumatic elbow instability | Pediatric Supracondylar Humerus Fracture 2020 Review | Purpose To determine if specific coronoid fractures relate to specific overall traumatic elbow instability injury patterns and to depict any relationship on fracture maps and heat maps. Methods We collected 110 computed tomography (CT) studies from patients with coronoid fractures. Fracture types and pattern of injury ... |
0 | Where is the human waist? Definitions, manual compared toscanner measurements | Reduction Mammoplasty for Female Breast Hypertrophy | Where exactly is the human waist? How do definitions work for women who deviate from the conventional body shape? Does the measuring instrument matter? Waist is conventionally understood to be a measurable zone within the abdominal region of the torso, a zone of considerable importance. There needs to be a good consist... |
1 | A spreading roots sign: Characteristic sign of the preliminary stage of medial meniscus posterior root tear on magnetic resonance imaging | AMP (Acute Meniscal Pathology) | BACKGROUND: Medial meniscus posterior root tears (MMPRTs) can result in the development of osteoarthritis or osteonecrosis. Clinical experience suggests that symptoms such as dull pain or discomfort in the popliteal area or the calf area, which are sometimes misdiagnosed as sciatic nerve pain, may precede impending rup... |
0 | Why we still perform arthroscopy in knee osteoarthritis: a multi-methods study | OAK 3 - Non-arthroplasty tx of OAK | BACKGROUND: Knee arthroscopy has historically been a common treatment for knee osteoarthritis. However, multiple Randomised Controlled Trials along with a Cochrane review has led NICE to recommend that arthroscopy is not used in the vast majority of patients that have knee osteoarthritis. These recommendations have bee... |
1 | Study protocol for a randomised controlled trial of meniscal surgery compared with exercise and patient education for treatment of meniscal tears in young adults | AMP (Acute Meniscal Pathology) | INTRODUCTION: Arthroscopic surgery is a very common orthopaedic procedure. While several trials have investigated the effect of knee arthroscopy for middle-aged and older patients with meniscal tears, there is a paucity of trials comparing meniscal surgery with non-surgical treatment for younger adults. The aim of this... |
0 | Continuous peripheral nerve blocks in clinical practice | AAHKS (8) Anesthetic Infiltration | Purpose of review: The present review highlights new insights into indications and guidance during procedures for continuous peripheral nerve blocks. Recent findings: Continuous peripheral nerve blocks consistently provide better analgesia than traditional systemic opioid-based analgesia. The literature shows that cont... |
0 | Analysis of the bicipital groove as a landmark for humeral head replacement | The Treatment of Pediatric Supracondylar Humerus Fractures AUC | Many anthropometric studies of the normal glenohumeral relationship have been performed in an effort to identify reference points for the correct placement of the humeral head prosthesis in shoulder arthroplasty. The bicipital groove offers a useful landmark for placement of the lateral fin of the prosthesis. However, ... |
0 | Pin site care: guidance and key recommendations | DoD SSI (Surgical Site Infections) | Pin site infection is the most common complication of external fixation, a complex orthopaedic procedure used to stabilise fractures and correct limb deformity. The care of pin sites has long been debated among healthcare professionals. It is widely acknowledged that there is a lack of high quality research in this are... |
0 | Endoscopic carpal tunnel release. The voice of polite dissent | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | It is ironic for us that our own studies, showing that neurolysis of the median nerve does not confer benefit in the primary OCTR, have been cited frequently as a reason for not needing to visualize the median nerve and that this indirectly has supported ECTR. Our recognition that even OCTR can cause significant compli... |
0 | Inverse relationship between preoperative radiographic severity and postoperative pain in patients with osteoarthritis who have undergone total joint arthroplasty | Surgical Management of Osteoarthritis of the Knee CPG | OBJECTIVES: To determine cross-sectionally the influence of risk factors on chronic pain following total joint replacement (TJR) of the knee (TKR) or the hip (THR). METHODS: Eight hundred sixty post-TKR and 928 post-THR patients were studied. Western Ontario and McMaster Osteoarthritis Index pain scores taken on averag... |
1 | Depression and posttraumatic stress disorder among road traffic accident victims managed in a Tertiary hospital in Southern Nigeria | DoD PRF (Psychosocial RF) | BACKGROUND: Psychological responses to traumatic events vary widely across different cultures but studies in the developing countries are scant. The objective of this study is to determine prevalence of depression and posttraumatic stress disorder (PTSD) among patients involved in road traffic accident (RTA) compared w... |
1 | Proliferation of the breast epithelium in relation to menstrual cycle phase, hormonal use, and reproductive factors | Reduction Mammoplasty for Female Breast Hypertrophy | The proliferative rate in normal breast epithelium from 58 women undergoing reduction mammoplastics was studied using the formalin resistant antibody Ki-S5, and related to age at operation, menstrual cycle phase, family history of breast cancer, height and weight, parity, and hormonal use. The breast tissue from women ... |
0 | Superior outcome of strut allograft-augmented plate fixation for the treatment of periprosthetic fractures around a stable femoral stem | Hip Fx in the Elderly 2019 | PURPOSE: This study was designed to compare the outcome of two surgical approaches for treating femoral periprosthetic fractures around a stable femoral stem. The hypothesis was that plate fixation alone might be associated with a higher complication rate due to insufficient mechanical stability. We also considered tha... |
0 | Fractures of the capitellum--a comparison of two fixation methods | The Treatment of Pediatric Supracondylar Humerus Fractures AUC | Isolated capitellar fractures are rare, accounting for only 1 per cent of all elbow fractures (Bryan and Morrey, The Elbow and its Disorders, 1985). Many different fixation methods have been described but no series has compared these treatment modalities because of the rarity of these fractures. This paper compares the... |
1 | Genetic factors related with early onset of osteonecrosis of the jaw in patients with multiple myeloma under zoledronic acid therapy | MSTS 2018 - Femur Mets and MM | Specific genetic polymorphisms (SNPs) have been correlated with the development of bisphosphonate-related osteonecrosis of the jaw (BRONJ) in small series. We screened 140 myeloma patients (36 patients with and 104 without BRONJ) for the presence of previously identified SNPs in PPARG and CYP2C8 genes. All the patients... |
0 | The versatility of the superomedial pedicle with various skin reduction patterns | Reduction Mammoplasty for Female Breast Hypertrophy | BACKGROUND: The inferior pedicle technique remains one of the most commonly used techniques in breast reduction surgery, despite lengthy operating times, poor nipple sensation, and bottoming-out over time. The superomedial pedicle in reduction mammaplasty has previously been described using limited incision patterns. T... |
0 | Failures of metal-backed unicompartmental arthroplasty | Surgical Management of Osteoarthritis of the Knee CPG | Thirty-one failed metal-backed unicompartmental arthroplasties (MBUKAs) were reviewed with respect to their etiology of failure. In 11 cases (35.5%), the failure mode was 'medial-lateral mismatch' (medial-lateral subluxation in the coronal plane). Six cases (19%) failed secondary to lack of ingrowth in uncemented prost... |
0 | Management of Marcus Gunn jaw winking synkinesis | Upper Eyelid and Brow Surgery | PURPOSE: To report the outcomes of a management protocol for Marcus Gunn jaw winking synkinesis. METHODS: The records of 31 patients (16 female, 15 male) presenting to a tertiary referral center with Marcus Gunn jaw winking synkinesis between 1993 and 2003 were retrospectively analyzed. Generally, patients with mild wi... |
1 | Comparison of the efficacy of ketoprofen phonophoresis, ultrasound, and short-wave diathermy in knee osteoarthritis | OAK 3 - Non-arthroplasty tx of OAK | The present study aimed to compare the efficacy of three different deep heating modalities: phonophoresis (PH), short-wave diathermy (SWD), and ultrasound (US), in knee osteoarthritis. Patients who consented to participate in the study were randomly divided into the following three groups. Group 1 (n = 33) received PH,... |
1 | Glenoid deformity in the coronal plane correlates with humeral head changes in osteoarthritis: a radiographic analysis | Glenohumeral Joint OA | BACKGROUND: A variety of measurements can be used to assess radiographic osteoarthritic changes of the shoulder. This study aimed to analyze the correlation between the radiographic humeral-sided Samilson and Prieto classification system and 3 different radiographic classifications describing the changes of the glenoid... |
0 | Hand therapy following elbow release for passive elbow flexion and long head of the triceps transfer for active elbow flexion in children with amyoplasia | Pediatric Supracondylar Humerus Fracture 2020 Review | Children born with the Amyoplasia form of arthrogryposis multiplex congenita (AMC) who lack elbow flexor muscles and have elbow extension contractures usually require assistance in performing ADL's that require reaching their hand to their face, head, and upper body. For tasks involving the UE, the elbow is the key to ... |
0 | Safety of bisphosphonates | MSTS 2018 - Femur Mets and MM | Bisphosphonates are one of the most well studied groups of medications and they are bone specific. This tissue specificity is a rare property for a drug introduced into clinical practice as long as 40. years ago. Over the years, the therapeutic boundaries of bisphosphonates were explored and their safety profile has wi... |
1 | Effect of a commercial hypocaloric diet in weight loss and post surgical morbidities in obese patients with chronic arthropathy, a randomized clinical trial | OAK 3 - Non-arthroplasty tx of OAK | INTRODUCTION: The aim of our study was to evaluate in patients with obesity and surgical indication of orthopaedic surgery for chronic osteoarthritis (hip or knee), the impact on weight loss, metabolic control and post surgical co morbidities of a hypocaloric commercial formula (Optisource) versus conventional nutritio... |
0 | Bipolar fresh osteochondral allografting of the tibiotalar joint | Surgical Management of Osteoarthritis of the Knee CPG | BACKGROUND: Tibiotalar arthritis in the young, active patient is a debilitating condition with limited treatment options. Bipolar tibiotalar fresh osteochondral allograft transplantation was conceived as a possible alternative to arthrodesis and arthroplasty. We reported our experience with bipolar ankle osteochondral ... |
0 | Anatomic study on medialis pedis flaps with saphenous nerve and repairing tissue defects adjacent to Achilles tendon | DoD LSA (Limb Salvage vs Amputation) | Background: Medialis pedis flaps have been widely used in the clinical practice due to their good color and luster, texture as well as the restoration of protective sensation. But little is known about the precise anatomic data of innervation of medialis pedis flaps. Objective: Based on identification of local anatomic... |
1 | Is L2 paravertebral block comparable to lumbar plexus block for postoperative analgesia after total hip arthroplasty? | AAHKS (9/10) Regional Nerve Blocks | BACKGROUND: Continuous lumbar plexus block (LPB) is a well-accepted technique for regional analgesia after THA. However, many patients experience considerable quadriceps motor weakness with this technique, thus impairing their ability to achieve their physical therapy goals.
QUESTIONS/PURPOSES: We asked whether L2 para... |
0 | High rates of undiagnosed and untreated osteoporosis in postmenopausal women receiving medical services in the area of Upper Silesia | Hip Fx in the Elderly 2019 | Introduction: High social cost and high risk of disability make postmenopausal osteoporosis one of major public health problem in the 21st century. The aim of this study was to assess frequency of undiagnosed and untreated osteoporosis in postmenopausal women in the Upper Silesia Region of Poland. Additionally, we comp... |
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