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0 | Varus-Producing Lateral Distal Femoral Opening-Wedge Osteotomy | OAK 3 - Non-arthroplasty tx of OAK | Valgus knee alignment in excess of physiological valgus leads to excessive loading of the lateral compartment, which can potentially increase the risk of osteoarthritis and can place the medial knee structures at risk of chronic attenuation. Varus-producing distal femoral osteotomies have been proposed for correction o... |
0 | Design and pilot testing of the DVA/Seattle Footwear System for diabetic patients with foot insensitivity | DoD LSA (Limb Salvage vs Amputation) | Clinical epidemiology studies suggest the majority of lower limb amputations were preceded by a minor traumatic event, often footwear-related, and lower limb ulcers. To reduce foot trauma and ulcers, the diabetic patient with foot insensitivity has unique footwear needs. To address these needs for patients not requirin... |
0 | Arthrowand technique under arthroscope in diagnosis and treatment of knee disease | AMP (Acute Meniscal Pathology) | OBJECTIVE: To summarize the clinical experience in diagnosis and treatment of knee disease by arthrowand technique under arthroscope. METHOD: Seventy-two patients were divided randomly into control and test groups (each 36 patients). The patients suffered from meniscectomy, synovitis and arthritis. The control group co... |
0 | A case of rheumatoid arthritis improved from steinbrocker classification class IV to class II after multi-joint surgery | PJI DX Updated Search | We report the case of a patient with rheumatoid arthritis (RA) who showed a reduction in disease severity (from class IV to class II) after multi-joint surgery. The patient was a 61-year-old man with a history of RA, type-2 diabetes, chronic obstructive pulmonary disease, and nephrotic syndrome. He had been undergoing ... |
0 | Principles of bone grafting: non-union, delayed union | DoD SSI (Surgical Site Infections) | Autologous bone grafts or autografts (i.e. grafts taken from the patient's bone) have been used to treat fracture non-unions and occasionally to treat acute fractures. Traditionally, autologous bone is harvested from the iliac crest through a generous open incision. This can result in significant pain and morbidity. No... |
0 | Immunohistochemical localisation of pS2 protein in ductal carcinoma in situ and benign lesions of the breast | Reduction Mammoplasty for Female Breast Hypertrophy | The expression of pS2 was examined histochemically in paraffin sections taken from biopsy material from patients diagnosed with ductal carcinoma in situ (DCIS). Often intense immunoreactivity, to an anti-pS2 monoclonal antibody, was observed in comedo, solid, cribriform and micropapillary types of DCIS, with significan... |
0 | Examination of the knee for MRCS OSCE | AMP (Acute Meniscal Pathology) | This article is intended as a guide to help improve and perfect your knee examination technique for the MRCS examination. The knee is a joint frequently assessed in the MRCS OSCE, due to the presence of reliable clinical signs in the chronic patient, who can easily attend for repeated examinations. The article will gui... |
0 | Patient-reported outcome after carpal tunnel release for advanced disease: a prospective and longitudinal assessment in patients older than age 70 | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | PURPOSE: Advanced stages of nerve compression are likely to result in irreversible intraneural changes including intrinsic fibrosis and axon loss, and advanced age is expected to compromise nerve regeneration and recovery. Although satisfactory outcomes have been reported we hypothesized that carpal tunnel release in a... |
0 | Circadian regulation of auditory function | DoD PRF (Psychosocial RF) | The circadian system integrates environmental cues to regulate physiological functions in a temporal fashion. The suprachiasmatic nucleus, located in the hypothalamus, is the master clock that synchronizes central and peripheral organ clocks to orchestrate physiological functions. Recently, molecular clock machinery ha... |
0 | Tumours of the external ear and temporal bone | MSTS 2018 - Femur Mets and MM | Symptoms such as hearing impairment, tinnitus, or a disturbance in sense of balance can generally be attributed to non-neoplastic causes, such as otitis media, otosclerosis, or trauma. Less commonly, auricular signs and symptoms are the result of non-neoplastic and neoplastic space-occupying lesions. The external ear c... |
0 | The checklist of nonverbal pain indicators (CNPI) | Management of Hip Fractures in the Elderly | This article critiques the literature on existing pain assessment instruments for cognitively impaired elders and reports findings of pilot testing of the Checklist of Nonverbal Pain Indicators. This instrument was designed to measure pain behaviors in cognitively impaired elders. Instrument testing was conducted on a ... |
0 | Clinical Outcome Measures in Arthroscopic Meniscectomy: Clinician versus Patient Completed Knee Scores | AMP (Acute Meniscal Pathology) | <b>Objective</b> The aim of the present study was to investigate the difference between clinician-completed and patient-completed outcome scores in detecting improvement following arthroscopic meniscectomy in patients with meniscal tears of the knee. <b>Methods</b> Thirty-four patients with meniscal tears were prospect... |
0 | Immunosuppressed microenvironment - an emerging target in prostate cancer Management | MSTS 2018 - Femur Mets and MM | Although the prognosis of metastatic castrate-resistant prostate cancer (mCRPC) has dramatically changed in the last decade, with median survivals improving from about a year to almost 3 years, current hormonal and chemotherapeutic approaches ultimately result in resistance. An enhanced understanding of the microenviro... |
0 | Evaluation of post-operative pain relief for local anaesthetic (LA) 0.5% Bupivacaine is administered to a patient prior to the closure of surgical wound for a distal forearm fracture using: method 1. Injection of LA subcutaneously around the wound site, prior to wound closure, while the patient is under a general anaes... | Distal Radius Fractures | INTERVENTION: Trade Name: Marcain Heavy Steripack, 0.5%w/v Solution for Injection Product Name: Marcain Heavy Steripack, 0.5%w/v Solution for Injection Pharmaceutical Form: Solution for injection Trade Name: Marcain Heavy Steripack, 0.5%w/v Solution for Injection Product Name: Marcain Heavy Steripack, 0.5%w/v Solution ... |
0 | Biomechanical differences between cases with suspected chronic exertional compartment syndrome and asymptomatic controls during running | DOD - Acute Comp Syndrome CPG | Chronic exertional compartment syndrome (CECS) has been hypothesised, following clinical observations, to be the result of abnormal biomechanics predominantly at the ankle. Treatment of CECS through running re-education to correct these abnormalities has been reported to improve symptoms. However no primary research ha... |
1 | The clinical significance of the palmaris longus tendon in the pathophysiology of carpal tunnel syndrome | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Carpal tunnel syndrome is associated with increased intracarpal canal pressure. The effect of tendon loading on intracarpal canal pressures is documented in biomechanical studies. Palmaris longus loading in wrist extension induces the greatest absolute increase in intracarpal canal pressure. Despite this fact, the palm... |
0 | Physical Therapy Prior to Total Knee Replacement | OAK 3 - Non-arthroplasty tx of OAK | In this study, the investigators are investigating the effects of physical therapy (PT) for treating high grade knee osteoarthritis (OA) in patients that are candidates for total knee replacement. Through the examination of patient outcomes, such as pain, stiffness, and physical function, the investigators will determi... |
0 | Psychotic disorder and traumatic brain injury | DoD PRF (Psychosocial RF) | Traumatic brain injury (TBI) can result in serious and disabling neuropsychiatric disorders, such as cognitive deficits and personality change, as well as severe and chronic psychosis. This review focuses on the relationship between TBI and schizophrenia-like psychosis (SLP) including its epidemiology, diagnostic crite... |
0 | The Oxford unicompartmental knee replacement for osteoarthritis | Surgical Management of Osteoarthritis of the Knee CPG | The Oxford unicompartmental knee replacement is a reliable treatment for medial knee compartment osteoarthritis, provided patients with the correct indications are chosen and the appropriate surgical expertise is available. The Oxford knee has been available since fall 2000 in Canada and since the early 1980's in Europ... |
0 | Inadequate timing of prophylactic antibiotics in orthopedic surgery. We can do better | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | BACKGROUND AND PURPOSE: There are rising concerns about the frequency of infection after arthroplasty surgery. Prophylactic antibiotics are an important part of the preventive measures. As their effect is related to the timing of administration, it is important to follow how the routines with preoperative prophylactic ... |
0 | Acetabular ossicles: Epidemiology and Correlation with Femoroacetabular impingement | Hip Fx in the Elderly 2019 | PURPOSE: The aim of this study was to investigate; 1) the prevalence, size and location of acetabular ossicles in general population; 2) differentiation between the characteristic types of acetabular ossicles: unfused ossification centers (true os acetabuli), rim fractures, labral calcifications and loose bodies; 3) co... |
0 | A staging system for soft-tissue sarcoma and its evaluation in relation to treatment | MSTS 2022 - Metastatic Disease of the Humerus | In order to define the significant factors for a staging system of soft-tissue sarcomas (STS), histologic and clinical findings in 190 adult patients with localized STS in the extremities and trunk were reviewed. The male-to-female ratio was 1.21. The histologic grading of tumors was defined according to the criteria r... |
0 | Evidence of feasibility etoricoxib therapy in osteoarthritis in elderly patients | OAK 3 - Non-arthroplasty tx of OAK | The article presents the results of a study of clinical efficacy in the treatment of etorikoxib pain in patients with osteoarthritis of the knee and hip joints in elderly patients. The study involved 296 patients with gonarthrosis and coxarthrosis. It is shown that etoricoxib effectively relieves pain, has an advantage... |
0 | Paediatric knee problems | Diagnosis and Treatment of Osteochondritis Dissecans AUC | The knee joint during childhood may be the site of both congenital and acquired disorders. Malfunction of the patellofemoral joint is the most common complaint, including the relative complexities of patellar pain. Abnormalities that affect the knee at different ages are discussed in terms of their anatomical location ... |
0 | Classifying prosthetic use via accelerometry in persons with transtibial amputations | DoD LSA (Limb Salvage vs Amputation) | Knowledge of how persons with amputation use their prostheses and how this use changes over time may facilitate effective rehabilitation practices and enhance understanding of prosthesis functionality. Perpetual monitoring and classification of prosthesis use may also increase the health and quality of life for prosthe... |
0 | The fate of acutely inflamed joints with a negative synovial fluid culture | Surgical Management of Osteoarthritis of the Knee CPG | PURPOSE: The purpose of this study was to evaluate the management and fate of acutely inflamed joints with a negative synovial fluid culture. METHODS: Between January and December 2009, all the patients who presented to our institution with an acutely inflamed joint and were subjected to microbiological assessment of t... |
0 | Impingement between the acetabular cup and the femoral neck after hip resurfacing arthroplasty | Management of Hip Fractures in the Elderly | Background: Loosening, femoral neck fracture, and metal ion release have been well documented after hip resurfacing arthroplasty, but impingement between the acetabular cup and the femoral neck has not. The goal of this study was to analyze radiographic findings that were presumed to represent impingement of the neck a... |
1 | Acellular Dermal Matrix-Assisted Direct-to-Implant Breast Reconstruction and Capsular Contracture: A 13-Year Experience | Acellular Dermal Matrix | BACKGROUND: Use of acellular dermal matrix for implant-based breast reconstruction appears to be associated with a lower incidence of capsular contracture compared with standard reconstruction. The majority of acellular dermal matrix studies were, however, of short duration; thus, long-term incidence of capsular contra... |
0 | Prognostic factors to survival of patients with chondroblastic osteosarcoma | MSTS 2022 - Metastatic Disease of the Humerus | This study was aimed to reveal the changes in survival rates and prognostic factors to survival of chondroblastic osteosarcoma (COS). Patients from the Surveillance, Epidemiology, and End Results (SEER) database were retrieved. Kaplan-Meier survival analysis and Cox proportional hazard model were used during analysis. ... |
0 | Meniscectomy leads to early changes in the mineralization distribution of subchondral bone plate | AMP (Acute Meniscal Pathology) | Purpose: It is generally recognized that the subchondral bone plate (SBP) is involved in development of osteoarthritis (OA). However, the pathophysiological significance is not yet clear. The goal of this study is to investigate the extent of the changes that occur in SBP of the tibial plateau in the early stages of ex... |
1 | Prognostic Factors to Determine Survivorship of Meniscal Allograft Transplant: A Systematic Review | AMP (Acute Meniscal Pathology) | BACKGROUND: There is much room for improvement and optimization of meniscal allograft survivorship.
PURPOSE: To understand prognostic factors for survivorship using evidence-based selection criteria in order to identify patients who would best benefit from meniscal allograft transplant (MAT).
STUDY DESIGN: Systematic r... |
0 | Surgical management of gynecomastia - A 10-year analysis | Panniculectomy & Abdominoplasty CPG | Background: Gynecomastia is defined as the benign enlargement of the male breast. Most studies on surgical treatment of gynecomastia show only small series and lack histopathology results. The aim of this study was to analyze the surgical approach in the treatment of gynecomastia and the related outcome over a 10-year ... |
0 | Intra-articular hip injection: does pain relief correlate with radiographic severity of osteoarthritis? | PJI DX Updated Search | OBJECTIVE: Intra-articular injection is being used widely for both diagnostic and therapeutic purposes in the hip. However, its efficacy is not always predictable in patients with hip osteoarthritis (OA). The purpose of this study was to determine whether the degree of radiographic severity of OA was predictive of the ... |
0 | Antibiotics-impregnated cement spacers in the first step of two-stage revision for infected totally replaced hip joints: report of ten trial cases | PJI DX Updated Search | BACKGROUND: Periprosthetic infection is one of the serious complications after total hip arthroplasty (THA). This study analyzed the perioperative and postoperative status of patients who underwent antibiotics-impregnated cement spacer technique in the first step of the two-stage revision. METHODS: Ten joints of the ni... |
0 | Triangular block bridge method for surgical treatment of complex proximal humeral fractures: theoretical concept, surgical technique and clinical results | Hip Fx in the Elderly 2019 | Introduction Criteria for classification, indication and choice of a surgical device to treat proximal humeral fractures are still controversial. We report an original technique based on a mechanical concept with a structural principle of a triangle as a rigid body applied to the humeral head fractures in association w... |
0 | Median incision of the upper pole in medial pedicle vertical mammaplasty | Reduction Mammoplasty for Female Breast Hypertrophy | BACKGROUND: The medial pedicle is commonly employed in vertical breast reduction. With this procedure, there is concern about pedicle compression, especially in large breast reductions when a relatively large medial pedicle is rotated into a smaller sized areolar opening.
OBJECTIVE: The author describes a technical ref... |
1 | Musculoskeletal disorders. When are they caused by hormone imbalance? | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Often, the source of a musculoskeletal problem can be traced to an endocrine disorder. For example, carpal tunnel syndrome is not uncommon in patients who are pregnant or have diabetes, hypothyroidism, or acromegaly. Joint problems and arthritis are other common findings in diabetes, pregnancy, and hyperparathyroidism.... |
0 | The association between pre-operative sepsis and 30-day mortality in hip fracture patients-A cohort study | Hip Fx in the Elderly 2019 | BACKGROUND: Post-operative sepsis considerably increases mortality, but the extent of pre-operative sepsis in hip fracture patients and its consequences are sparsely elucidated. The aim of this study was to assess the association between pre-operative sepsis and 30-day mortality after hip fracture surgery.
METHODS: We ... |
0 | [Allogenic meniscus transplantation] | AMP (Acute Meniscal Pathology) | OBJECTIVE: Total replacement of the meniscus to reduce pain and improve joint function.
INDICATIONS: Symptomatic early arthrosis of the lateral compartment in young patients after loss of the lateral meniscus. Loss of the medial meniscus and anterior knee instability in young, active patients.
CONTRAINDICATIONS: Advanc... |
0 | Functional independence training program: an example of a sub-acute care model for patients following primary joint replacement | Surgical Management of Osteoarthritis of the Knee CPG | The Orthopaedic and Arthritic Hospital is a specialty institution dedicated to the provision of elective reconstructive orthopaedic surgery and rehabilitation to individuals with musculoskeletal disorders. This facility is the largest volume joint replacement centre in Canada, performing over 1,000 hip and knee replace... |
0 | Patient obesity: A growing concern of successful total knee arthroplasty | PJI DX Updated Search | The study reviews the outcome of total knee arthroplasty in obese patients. Knee arthroplasty in obese patients is a more technically challenging procedure. It carries a higher risk of postoperative infection, and the final functional score may not be as good as that of the nonobese patient. However, the pain relief an... |
0 | Mechanisms of regional anaesthesia protection against hyperalgesia and pain chronicization | Surgical Management of Osteoarthritis of the Knee CPG | Purpose of review: The aim of the present review is to describe how regional anaesthesia might oppose neuronal changes that surgery and opioids cause in the central nervous system to block both pain sensitization and chronicization following surgery. This might help anaesthesiologists to better understand the impact of... |
0 | Effects of the dual sodium–glucose linked transporter inhibitor, licogliflozin vs placebo or empagliflozin in patients with type 2 diabetes and heart failure | Hip Fx in the Elderly 2019 | Aims: Explore the efficacy, safety and tolerability of the dual sodium–glucose cotransporter (SGLT) 1 and 2 inhibitor, licogliflozin in patients with type-2 diabetes mellitus (T2DM) and heart failure. Methods: This multicentre, parallel-group phase IIA study randomized 125 patients with T2DM and heart failure (New York... |
0 | Training with Hybrid Assistive Limb for walking function after total knee arthroplasty | OAK 3 - Non-arthroplasty tx of OAK | BACKGROUND: The Hybrid Assistive Limb (HAL, CYBERDYNE) is a wearable robot that provides assistance to patients while walking, standing, and performing leg movements based on the intended movement of the wearer. We aimed to assess the effect of HAL training on the walking ability, range of motion (ROM), and muscle stre... |
0 | Gentamicin ointment versus petrolatum for management of auricular wounds | Reconstruction After Skin Cancer | BACKGROUND: Surgeons frequently create defects on the ear in the treatment of cutaneous malignancies. Potentially significant complications of second-intention healing on the ear are suppurative and inflammatory chondritis. Consequently, many physicians advocate the use of oral or topical prophylactic antibiotics after... |
0 | Clinical characteristics of human brucellosis in patients with various monoarticular involvements | Glenohumeral Joint OA | The aim of the study was to determine the main demographic, epidemiological, clinical characteristics, and outcome in patients with various types of brucellar monoarticular involvement. Retrospectively, we analyzed medical histories of 331 patients with brucellar monoarticular involvement who were treated at the infect... |
0 | Complications Related to Hamstring Tendon Harvest | DoD LSA (Limb Salvage vs Amputation) | The semitendinosus, gracilis, and patellar tendons are the most commonly harvested grafts for anterior cruciate ligament reconstruction. The use of hamstring autografts offers the advantage of preserved quadriceps function, decreased anterior knee pain, and reduced risk of patellar tendon rupture and patellar fracture ... |
0 | Autologous gluteal lipograft | Panniculectomy & Abdominoplasty CPG | In the past 25 years, several different techniques of lipoinjection have been developed. The authors performed a prospective study to evaluate the patient satisfaction and the rate of complications after an autologous gluteal lipograft among 351 patients during January 2002 and January 2008. All the patients included i... |
1 | Quality of lidocaine analgesia with and without midazolam for intravenous regional anesthesia | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Purpose: Midazolam has analgesic effects mediated by gamma aminobutyric acid-A receptors. This study was designed to evaluate the effect of midazolam on anesthesia and analgesia quality when added to lidocaine for intravenous regional anesthesia (IVRA). Methods: Forty patients undergoing hand surgery were randomly assi... |
0 | Osteoarthritis in the disabled population: a mechanical perspective | OAK 3 - Non-arthroplasty tx of OAK | Primary disabling conditions, such as amputation, not only limit mobility, but also predispose individuals to secondary musculoskeletal impairments, such as osteoarthritis (OA) of the intact limb joints, that can result in additive disability. Altered gait biomechanics that cause increased loading of the intact limb ha... |
1 | MRI of the knee ligaments and menisci: comparison of isotropic-resolution 3D and conventional 2D fast spin-echo sequences at 3 T | AMP (Acute Meniscal Pathology) | OBJECTIVE: The purpose of this study was to evaluate the diagnostic performance of sampling perfection with application-optimized contrasts using different flip-angle evolutions (SPACE) 3D fast spin-echo acquisition relative to conventional 2D fast spin-echo acquisition in the 3-T MRI evaluation of the menisci and liga... |
0 | A hyaluronic acid-based hydrogel enabling CD44-mediated chondrocyte binding and gapmer oligonucleotide release for modulation of gene expression in osteoarthritis | OAK 3 - Non-arthroplasty tx of OAK | Hyaluronic acid (HA) is an attractive biomaterial for osteoarthritis (OA) treatment due to inherent functional and compatibility properties as an endogenous knee joint component. In this work, we describe a HA-based hydrogel with the dual functionality of increased CD44-dependent chondrocyte binding and controlled rele... |
0 | Effects of antibiotics on dental implants: a review | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | There are many reasons for dental implant failure, the development of bacteremia is concern for dentists. This is due to the possibility of unfavorable result such as implant loss or the need for re-treatment. In general, antibiotic prophylaxis is recommended for high risk patients such as individuals with an immunodef... |
0 | Pulmonary edema in meningococcal septicemia associated with reduced epithelial chloride transport | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | OBJECTIVES: To test the hypothesis that meningococcal septicemia-related pulmonary edema is associated with a systemic abnormality of epithelial sodium and chloride transport and to investigate an association with hormones regulating Na transport. DESIGN: Prospective observational study. SETTING: The 24-bed pediatric i... |
0 | Tantalum Components in Difficult Acetabular Revisions Have Good Survival at 5 to 10 Years: Longer Term Followup of a Previous Report | Developmental Dysplasia of the Hip 2020 Review | BACKGROUND: The best method for acetabular revisions in patients with severe bone loss remains controversial; typical approaches include jumbo cups, cages, cup-cages, and custom components. Tantalum (TM) components have good results at midterm followup, but the longer term survival and complications are not available. ... |
0 | Loss of Independence After Operative Management of Femoral Neck Fractures | Hip Fx in the Elderly 2019 | OBJECTIVES: The FAITH trial evaluated effects of sliding hip screws versus cancellous screws in femoral neck fracture patients. Using FAITH trial data, we quantified changes in living status, use of aids, and investigated factors associated with living and walking independently 12 months after fracture.
METHODS: We con... |
0 | A 2-step non-surgical procedure and systemic antibiotics in the treatment of rapidly progressive periodontitis | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | BACKGROUND: In the last few years knowledge about periodontal infections has increased enormously, nevertheless practitioners are still seeking guidelines for suitable treatment concepts. METHODS: The aim of this study was to examine the effect of doxycycline, metronidazole, and clindamycin used adjunctively in a 2-ste... |
0 | Efficacy and safety of femoral vascular access for peripheral blood stem cell (PBSC) collection | MSTS 2018 - Femur Mets and MM | Central venous catheters are frequently used in leukapheresis to provide high flow rates. The most common locations are the subclavian or jugular vein, but insertion-related complications and inadequate flow are frequent problems. Experience using femoral venous access is limited, because this has been discouraged due ... |
0 | Malignancy in chronic ulcers and scars of the leg (Marjolin's ulcer): A study of 21 patients | DoD LSA (Limb Salvage vs Amputation) | Objective. To study the imaging features of patients with chronic ulcers of the leg that were associated with malignancy. Design and patients. All patients who on biopsy were proven to have malignancy - the majority of which were squamous cell carcinoma - were included in a prospective study. Ulcers limited to the foot... |
0 | HIV-associated lipodystrophy: Pathogenesis, prognosis, treatment, and controversies | Panniculectomy & Abdominoplasty CPG | Potent antiretroviral agents markedly suppress HIV and have dramatically improved the clinical course, prognosis, and survival of HIV-infected patients. Unfortunately, highly active antiretroviral therapy is often compromised by metabolic complications, including insulin resistance, dyslipidemia, and fat redistribution... |
0 | Orofacial infections of odontogenic origin | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | Purulent infections of the orofacial region are often of odontogenic origin. The clinical manifestations are largely dependent on the complex microbiota and the anatomical routes of spread. Serious complications may ensue, especially if hematogenous spread occurs. Direct invasion of different anatomical spaces may caus... |
0 | Complex posterior fracture-dislocation of the shoulder. Epidemiology, injury patterns, and results of operative treatment | MSTS 2022 - Metastatic Disease of the Humerus | BACKGROUND: Complex posterior fracture-dislocations of the shoulder are rare and often associated with poor long-term function regardless of the choice of treatment. The purposes of this study were to evaluate the epidemiology and pathological anatomy of posterior fracture-dislocations of the shoulder and to assess the... |
0 | Results of ulnar shortening osteotomy for ulnocarpal abutment after malunited distal radius fracture | Distal Radius Fractures | Surgical correction for ulnocarpal abutment syndrome after malunited distal radius fracture remains controversial. We reviewed sixteen patients (7 men, 9 women) who underwent isolated ulnar-shortening osteotomy for ulnar wrist pain as their main complaint. Mean age was 48 years. The range of flexion-extension increased... |
0 | Mixed cell therapy of bone marrow-derived mesenchymal stem cells and articular cartilage chondrocytes ameliorates osteoarthritis development | AMP (Acute Meniscal Pathology) | Of the many cell-based treatments that have been tested in an effort to regenerate osteoarthritic articular cartilage, none have ever produced cartilage that compare with native hyaline cartilage. Studies show that different cell types lead to inconsistent results and for cartilage regeneration to be considered success... |
0 | A Double-blind comparison of naproxen against indometacin in osteoarthrosis | OAK 3 - Non-arthroplasty tx of OAK | Fifty patients with osteoarthrosis of the knee and hip were entered into a doubleâ?blind trial of dâ?2â?(6'â?methoxyâ?2â?naphthyl)â?propionic acid (naproxen) 500 mg daily versus indometacin 100 mg daily. Two simultaneous trials of identical design were performed, one consisting of patients with unilateral or bil... |
0 | Birmingham hip resurfacing: the prevalence of failure | PJI DX Updated Search | Despite the increasing interest and subsequent published literature on hip resurfacing arthroplasty, little is known about the prevalence of its complications and in particular the less common modes of failure. The aim of this study was to identify the prevalence of failure of hip resurfacing arthroplasty and to analys... |
0 | Postoperative TENS pain relief after knee surgery: objective evaluation | Surgical Management of Osteoarthritis of the Knee CPG | A comparison was made between the pain-relieving effect of placebo-transcutaneous electrical nerve stimulation (TENS), high frequency TENS, and epidural analgesia with dilute local anesthetics in 15 patients with open knee surgery. Assessment of pain was compared with the patients' ability to contract their quadriceps ... |
0 | Non-steroidal anti-inflammatory drugs for preventing heterotopic bone formation after hip arthroplasty | Management of Hip Fractures in the Elderly | BACKGROUND: Heterotopic bone formation (HBF) in the soft tissues surrounding the hip joint is a frequent complication of hip surgery. Non-steroidal anti-inflammatory drugs (NSAIDs) administered in the immediate perioperative period reduce the risk of HBF. However, the magnitude of the effect on HBF, and the effects on ... |
0 | Prevalence and predictors of anxiety disorders amongst low-income pregnant women in urban South Africa: a cross-sectional study | DoD PRF (Psychosocial RF) | Anxiety is highly prevalent in many populations; however, the burden of anxiety disorders amongst pregnant women in low-resource settings is not well documented. We investigated the prevalence and predictors of antenatal anxiety disorders amongst low-income women living with psychosocial adversity. Pregnant women were ... |
0 | Understanding and optimizing the antibacterial functions of anodized nano-engineered titanium implants | Dental Implant Infection | Nanoscale surface modification of titanium-based orthopaedic and dental implants is routinely applied to augment bioactivity, however, as is the case with other cells, bacterial adhesion is increased on nano-rough surfaces. Electrochemically anodized Ti implants with titania nanotubes (TNTs) have been proposed as an id... |
0 | The allogeneic dilemma | MSTS 2018 - Femur Mets and MM | The place of allogeneic SCT in the management of multiple myeloma remains controversial. Although it may induce long-term clinical and molecular remissions, the very high transplant-related toxicity after a myeloablative preparative regimen has limited its role to younger patients as first-line treatment option. Even w... |
0 | Voltage-gated Sodium Channel Activity Promotes Cysteine Cathepsin-dependent Invasiveness and Colony Growth of Human Cancer Cells | MSTS 2018 - Femur Mets and MM | Voltage-gated sodium channels (Na(V)) are functionally expressed in highly metastatic cancer cells derived from nonexcitable epithelial tissues (breast, prostate, lung, and cervix). MDA-MB-231 breast cancer cells express functional sodium channel complexes, consisting of Na(V)1.5 and associated auxiliary beta-subunits,... |
0 | Delayed-onset peripheral blood cytopenia after rituximab: Frequency and risk factor assessment in a consecutive series of 77 treatments | MSTS 2022 - Metastatic Disease of the Humerus | The occurrence of unexplained peripheral blood cytopenia, particularly neutropenia, has been recently reported after rituximab. Its prevalence may be underestimated since it may occur late after treatment. This study analysed all cases of unexplained delayed-onset peripheral blood cytopenia of WHO grade II-IV occurring... |
1 | Psychosocial buffers of traumatic stress, depressive symptoms, and psychosocial difficulties in veterans of Operations Enduring Freedom and Iraqi Freedom: the role of resilience, unit support, and postdeployment social support | DoD PRF (Psychosocial RF) | BACKGROUND: Little research has examined the role of protective factors such as psychological resilience, unit support, and postdeployment social support in buffering against PTSD and depressive symptoms, and psychosocial difficulties in veterans of Operations Enduring Freedom (OEF) and Iraqi Freedom (OIF).
MATERIALS A... |
0 | Dislocation rate after hip arthroplasty within the first postoperative year: 36mm versus 28mm femoral heads | PJI DX Updated Search | Abstract: Dislocation is a common and important complication of total hip arthroplasty (THA). Largerfemoral heads may reduce the risk of dislocation and improve the range of movement. The aim ofthis study was to compare the relative risk (RR) of dislocation during the first year after THA betweenimplants with 28mm and ... |
0 | Infective endocarditis, the conundrum of antibiotic prophylaxis | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | Infective endocarditis (I.E.) is a common bacterial infection of the endocardium, which before the advent of antibiotics, had a high mortality rate. Endocarditis has been described as a serious and a potentially fatal condition in which the heart beats in a muffled march towards the grave, in quick time in the acute fo... |
1 | Complementary therapies for osteoarthritis: are they effective? | OAK 3 - Non-arthroplasty tx of OAK | Increasing interest has focused on complementary management modalities, including tai chi, acupuncture, yoga, and massage therapy, as treatments for osteoarthritis (OA). This review article synthesizes evidence from randomized controlled trials (RCTs) and systematic reviews (SRs) that examined one or more of the above ... |
0 | Interleukin-34 Synovial Fluid Was Associated with Knee Osteoarthritis Severity: A Cross-Sectional Study in Knee Osteoarthritis Patients in Different Radiographic Stages | OAK 3 - Non-arthroplasty tx of OAK | Background: Inflammation might play a crucial role in the pathogenesis of osteoarthritis (OA). Interleukin-34 (IL-34) is a well-known proinflammatory cytokine.
Objective: The objective of this study was to detect IL-34 levels in serum and synovial fluid (SF) of patients with OA and to investigate their correlation with... |
0 | Implant standardization for hemiarthroplasty: implementation of a pricing matrix system at a level II community based trauma system | Hip Fx in the Elderly 2019 | Our purpose was to perform a clinical and financial analysis of a pricing matrix system on operative hip fracture care concerning hemiarthroplasty for displaced femoral neck fractures in elderly low demand patients. Data analysis on 81 pre-matrix and 88 post-matrix patients demonstrated no significant differences in ag... |
0 | Body contouring in the obese patient | Reduction Mammoplasty for Female Breast Hypertrophy | Obese patients have not been commonly considered as candidates for body contouring surgery. Using circumferential liposuction techniques, in association with the tumescent technique, and circumferential excisional procedures, this patient population can achieve significant body transformation with acceptably low morbid... |
0 | Juxta-articular myxoma: a clinical and pathologic study of 65 cases | AMP (Acute Meniscal Pathology) | We describe 65 cases of juxta-articular myxoma (JAM) that occurred in the vicinity of large joints, possessed histologic features of a myxoma, and were frequently associated with cystic changes that resembled a ganglion cyst. The vast majority of cases (57, 88%) occurred in the region of the knee; a minority involved t... |
0 | Distal radius fractures-Design of locking mechanism in plate system and recent surgical procedures | Distal Radius Fractures | Recently, many studies have emphasized the importance of the comprehension of detailed functional anatomy of the distal forearm and wrist joint, and their biomechanics. A significant contribution which yields good functional outcomes of surgical treatment was the development of the locking plate technology; this techno... |
0 | Diffusion tensor imaging can detect the early stages of cartilage damage: a comparison study | AMP (Acute Meniscal Pathology) | BACKGROUND: In the present study, we measured damaged areas of cartilage with diffusion tensor (DT) imaging and T2 mapping, and investigated the extent to which cartilage damage could be determined using these techniques.
METHODS: Forty-one patients underwent arthroscopic knee surgery for osteoarthritis of the knee, a ... |
1 | Determinants of surgical delay for hip fracture | Management of Hip Fractures in the Elderly | BACKGROUND AND OBJECTIVE: Recent guidelines recommend early surgical treatment of hip fractures in the elderly. The aim of the present study is to analyse the factors delaying surgical treatment of hip fractures in elderly patients by more than 2 days and to investigate whether these factors are consistent between a te... |
1 | Can a single dose of 300 mg of pregabalin reach acute antihyperalgesic levels in the central nervous system? | AAHKS (5) Gabapentinoids | BACKGROUND AND OBJECTIVES: Central spinal cord sensitization can occur during surgery and may lead to persistent pain after surgery. Pregabalin has been shown to decrease central sensitization in experimental pain paradigms, and so the same antihyperalgesic effect of pregabalin may occur during and immediately after su... |
0 | Biochemical parameters of vitamin D nutriture in old people in Jerusalem | Management of Hip Fractures in the Elderly | Serum 25-hydroxycholecalciferol (25[OH]D3) levels and other parameters of vitamin D nutriture were examined in 58 subjects aged 70 or more, living in Jerusalem. They were compared with those of 54 young adults living in the same neighbourhood. No evidence was obtained of a lower level of vitamin D nutriture in the elde... |
0 | Smoking and alcohol behaviours in people following hip and knee arthroplasty: Data from the Osteoarthritis Initiative | OAK 3 - Non-arthroplasty tx of OAK | Background: Smoking and alcohol consumption has a negative effect on overall health. Limited evidence has been presented as to how these health behaviours may change between pre- and postoperative intervals in the initial 12 months post-arthroplasty. The purpose of this study was to address this uncertainty. Hypothesis... |
0 | Arthroscopic meniscectomy: a follow-up report | AMP (Acute Meniscal Pathology) | Eighty patients who underwent arthroscopic meniscectomy were interviewed and examined 12 to 24 months postoperatively. Twenty-seven (34%) of the patients rated their knees as normal, and 46 (58%) of the patients rated their knees as improved. Seventy-nine percent of the patients were pain free at the time of followup. ... |
0 | GRK5 Inhibition Attenuates Cartilage Degradation via Decreased NF-kappaB Signaling | AMP (Acute Meniscal Pathology) | OBJECTIVE: NF-kappaB-dependent signaling is an important modulator in osteoarthritis (OA), and G protein-coupled receptor kinase 5 (GRK5) regulates the NF-kappaB pathway. This study was undertaken to investigate the functional involvement of GRK5 in OA pathogenesis.
METHODS: GRK5 expression in normal and OA human knee ... |
1 | Computer navigation and total knee arthroplasty | Surgical Management of Osteoarthritis of the Knee CPG | Research has added evidence in favor of computer-navigated techniques over conventional surgery for total knee arthroplasty (TKA). The goal of the current meta-analysis was to compare the outcome of outliers in mechanical axis and postoperative complications in patients undergoing conventional vs computer-navigated tec... |
0 | Effects of percutaneous compression plate versus proximal femoral nail anti-rotation internal fixation on the postoperative functional recovery and femoral head rotation and nail slippage in elderly patients with stable intertrochanteric fracture | Hip Fx in the Elderly 2019 | BACKGROUND: Senile unstable intertrochanteric fractures are usually treated with intramedullary nail fixation, but for stable intertrochanteric fractures, extramedullary fixation and intramedullary nail both can obtain satisfactory curative efficacy. Therefore, surgical options are still a controversy. OBJECTIVE: To in... |
0 | Fresh stored allografts for the treatment of osteochondral defects of the knee | Diagnosis and Treatment of Osteochondritis Dissecans AUC | Background: Osteochondral allograft reconstruction of articular cartilage defects is a well-established cartilage repair strategy. Currently, fresh osteochondral allograft tissue is commercially available to clinicians approximately thirty days following graft harvest. Little clinical information is available on the ou... |
0 | Effect of medial collateral ligament release and osteophyte resection on medial laxity in total knee arthroplasty | AMP (Acute Meniscal Pathology) | PURPOSE: The concept of medial stabilizing technique total knee arthroplasty (MST-TKA) is to minimize the medial release without the superficial layer of medial collateral ligament (MCL). However, it is unclear at what stage the proper medial laxity is obtained during surgery. The purpose of this study was to investiga... |
0 | The unique biology of lymphatic edema | Panniculectomy & Abdominoplasty CPG | Sadly, the subject of lymphatic vascular insufficiency continues to engender relative neglect by health care professionals, which represents a source of frustration and fear among patients. A re-consideration of the unique, complex biology of lymphatic vascular disorders has the capacity both to reinvigorate interest a... |
0 | Universal intramedullary instrumentation for unicompartmental total knee arthroplasty | Surgical Management of Osteoarthritis of the Knee CPG | Certainly the advantages of unicompartmental total knee arthroplasty (TKA) are appealing as opposed to tricompartmental arthroplasty. Patients who have had unicompartmental arthroplasty have significant preservation of existing bone stock. They have an improved range of motion and they are definitely easier to revise. ... |
0 | Regeneration of Osteochondral Defects by Combined Delivery of Synovium-Derived Mesenchymal Stem Cells, TGF-ß1 and BMP-4 in Heparin-Conjugated Fibrin Hydrogel | Osteochondritis Dissecans 2020 Review | The regeneration of cartilage and osteochondral defects remains one of the most challenging clinical problems in orthopedic surgery. Currently, tissue-engineering techniques based on the delivery of appropriate growth factors and mesenchymal stem cells (MSCs) in hydrogel scaffolds are considered as the most promising t... |
0 | High-dose intravenous immunoglobulin therapy for systemic capillary leak syndrome (Clarkson disease) | DOD - Acute Comp Syndrome CPG | BACKGROUND: Systemic capillary leak syndrome is a highly rare disorder of unknown cause. The disease is characterized by episodes of transient vascular collapse, which leads to hypotensive shock and anasarca. Previous treatment of this potentially devastating condition has been largely ineffective. We evaluated intrave... |
1 | Late diagnosis of congenital dislocation of the hip and presence of a screening programme: South Australian population-based study | Developmental Dysplasia of the Hip CPG | BACKGROUND: The Medical Research Council Working Party on Congenital Dislocation of the Hip have reported an ascertainment-adjusted incidence of a first operative procedure for congenital dislocation of the hip (CDH) of 0.78 per 1000 livebirths, which is similar to the incidence of CDH before the start of the UK screen... |
0 | Hfe C282Y/H63D compound heterozygotes are at lower risk of hemochromatosis-related arthropathy | Surgical Management of Osteoarthritis of the Knee CPG | Background Arthropathy that mimics osteoarthritis (OA) and osteoporosis (OP) are considered classic complications of hereditary hemochromatosis (HH). There are limited data comparing OA and OP among HH patients with different HFE genotypes. Objectives We investigated whether C282Y homozygosity was associated with an in... |
0 | Glenoid Dysplasia | Glenohumeral Joint OA | Glenoid dysplasia is a developmental anomaly of the scapula that is characterized by a bony deficiency of the posteroinferior glenoid and the adjacent scapular neck. Glenoid dysplasia may occur as a primary isolated condition or in association with various syndromes. It is thought to be related to defective ossificatio... |
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