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1 | A long-term, prospective, randomized study comparing biodegradable and metal interference screws in anterior cruciate ligament reconstruction surgery: radiographic results and clinical outcome | Anterior Cruciate Ligament Injuries CPG | BACKGROUND: During the past decade, the use of biodegradable implants in anterior cruciate ligament surgery has increased. HYPOTHESIS: Poly-L-lactide acid (PLLA) interference screws would render the same clinical results but greater tunnel enlargement than metal screws 8 years after anterior cruciate ligament reconstru... |
0 | Endoscopic abdominoplasty: an alternative approach | Panniculectomy & Abdominoplasty CPG | We describe a technique for endoscopic abdominoplasty in which we used 3 incisions, following the triangulation principles. To maintain the subcutaneous cavity, CO2 was insufflated at 8 mm Hg, and Esmarch bandages were placed at the submammary fold in a circumferential way to prevent subcutaneous emphysema. The aponeur... |
0 | Levels of SC5b--9 complement complex in plasma and synovial fluid of patients with rheumatic disease | AMP (Acute Meniscal Pathology) | Activation of the terminal complement pathway leads to formation of the C5b--9 complex. The main effects of C5b--9 generation are tissue injury by cell lysis or by stimulation of proinflammatory mediators. In a study carried out in 42 patients, using polyclonal antibodies against C5b--9 neoantigens and C9 in an ELISA a... |
0 | Tibial plateau fractures in elderly patients | Management of Hip Fractures in the Elderly | Tibial plateau fractures are complex injuries which, if not adequately treated, can lead to invalidating sequelae. They constitute on average about 1% of all fractures, and up to 8% in patients over 65 years, and can be caused by both high- and low-energy trauma. Unlike in younger subjects, treatment of tibial plateau ... |
1 | Pharmacist-initiated intervention trial in osteoarthritis: a multidisciplinary intervention for knee osteoarthritis | OAK 3 - Non-arthroplasty tx of OAK | OBJECTIVE: Knee osteoarthritis (OA) is a commonly undiagnosed condition and care is often not provided. Pharmacists are uniquely placed for launching a multidisciplinary intervention for knee OA.
METHODS: We performed a cluster randomized controlled trial with pharmacies providing either intervention care or usual care... |
0 | Interdisciplinary family intervention program: a partnership among health professionals, traumatic brain injury patients, and caregiving relatives | DoD PRF (Psychosocial RF) | Throughout the delivery of care after traumatic brain injury, the type of relationship that develops between the family and the professionals has a major effect on the day-by-day adjustment of traumatic brain injury individuals and their relatives. Seventeen health professionals from different disciplines working with ... |
1 | Current Status of Cost Utility Analyses in Total Joint Arthroplasty: A Systematic Review | Surgical Management of Osteoarthritis of the Knee CPG | BACKGROUND: Total joint arthroplasty (TJA), although considered to be highly beneficial, is associated with substantial costs to the US healthcare system. Cost utility analysis has become an increasingly important means to objectively evaluate the value of a healthcare intervention from the perspective of both extendin... |
1 | Reconstruction of the anterior cruciate ligament using a patellar tendon autograft. A long term follow up | Anterior Cruciate Ligament Injuries CPG | Three hundred and eighty-four athletes with chronic anterior cruciate instability were treated by a free autologous graft of the lateral third of the patellar tendon. Evaluation 5 to 9 years after operation was carried out in 334 cases by physical examination, the KT-1000 arthrometer and the Tegner and Lysholm scoring ... |
0 | Complications of metalwork removal | DoD SSI (Surgical Site Infections) | A total of 188 patients who had metalwork removed were reviewed. There was an overall 20 per cent complication rate. The highest complication rate of 42 per cent was seen with forearm fractures. Infection was the most common complication, and was particularly high in those fractures which were originally open (43 per c... |
0 | Nerve injuries associated with wrist trauma | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Although nerve injury rarely accompanies wrist trauma or disease, the long-term functional result frequently depends more on resolution of the nerve deficit and symptoms than on resolution of the basic orthopedic pathology. The origins of nerve injury associated with orthopedic problems are reviewed, and a rational app... |
0 | Sensitivity to acute cerebral ischemic injury in migraineurs: A retrospective case-control study | DoD PRF (Psychosocial RF) | Objective: Migraine, particularly with aura, is a risk factor for ischemic stroke. Recent data in migraine mutant mice suggest that cerebral hyperexcitability associated with migraine accelerates recruitment of ischemic penumbra into the core, resulting in faster infarct growth compared with wild type. We hypothesized ... |
0 | Recurrent carpal tunnel syndrome. Clinical testing indicating incomplete section of the flexor retinaculum | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Based on five observations of recurrent carpal tunnel syndrome, a distally incomplete section of the flexor retinaculum can be identified on clinical grounds: the wrist flexion test becomes negative and the tourniquet test still remains positive |
0 | Mammaplasty-associated mycobacterial infection: a survey of plastic surgeons | Reduction Mammoplasty for Female Breast Hypertrophy | In a 3 1/2-year period, periprosthetic infections due to Mycobacterium fortuitum complex organisms complicated augmentation mammaplasty in at least 17 women. To determine the magnitude of the problem and to identify possible risk factors for infection, we conducted a questionnaire survey of 2062 members of the American... |
0 | Homograft aortic root replacement to correct infective endocarditis requiring seven open cardiac procedures | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | Infective endocarditis, presumably from a septic dental focus, affecting the aortic valve was seen as acute aortic regurgitation in a 20-year-old woman. Seven open cardiac procedures for replacement of the aortic valve and left ventricular outflow tract were performed over the subsequent 6 years. Aortic root replacemen... |
0 | FDG and FDG-labelled leucocyte PET/CT in the imaging of prosthetic joint infection | Hip Fx in the Elderly 2019 | PURPOSE: The demand for arthroplasty is rapidly growing as a result of the ageing of the population. Although complications such as heterotrophic ossification, fracture and dislocation are relatively rare, differentiating aseptic loosening, the most common complication of arthroplasty from infection, is a major challen... |
0 | Antibiotic prophylaxis in bacterial infection of type IIIA open fracture of tibial shaft with or without fibula fracture | DoD LSA (Limb Salvage vs Amputation) | Background: A major purpose of treating open fractures is the prevention of wound infection. Infection, as a major complication associated with open fractures, may lead to limb loss, sepsis, and even death. In this study, we survey factors affecting infection. Objectives: In this study, we survey factors affecting infe... |
0 | Impact on outcomes (long term postsurgical function) | Surgical Management of Osteoarthritis of the Knee CPG | INTRODUCTION: The patient undergoing orthopedic surgery rises the dual problem of the mandatory success on the functional status of surgery and pain exacerbation during joint movements required to obtain the expected result. The postoperative pain is justified by the overriding interest of the latter in the local or sy... |
0 | Comparison of central venous and external jugular venous pressures during repair of proximal femoral fracture | AAHKS (8) Anesthetic Infiltration | Background: External jugular venous pressure (EJVP) is a close estimate of central venous pressure (CVP) in patients undergoing mechanical ventilation in the supine position, but the effects of spontaneous respiration and posture on this relationship are not known. In this study, we compared CVP with EJVP measurements ... |
0 | Long-term followup of fresh femoral osteochondral allografts for posttraumatic knee defects | AMP (Acute Meniscal Pathology) | Fresh osteochondral allografts were used to repair articular defects in the distal femur in 72 patients. Sixty patients were available for long-term followup (mean, 10 years) to determine graft survivorship and patient outcomes using a modified Hospital for Special Surgery score. Twelve of 60 grafts have failed with th... |
0 | Benefits of radial head excision in patients with haemophilia: mid-term functional results | Distal Radius Fractures | INTRODUCTION: Recurrent haemarthrosis in haemophilic patients result with arthropathy of the radiocapitellar joint and blockage of the forearm rotation.
AIM: The aim of this study is to evaluate the mid-term results of radial head excision with partial synovectomy in severe haemophilic patients retrospectively.
METHODS... |
0 | Hemi-bucket-handle tears of the meniscus: appearance on MRI and potential surgical implications | AMP (Acute Meniscal Pathology) | OBJECTIVES: To describe a type of meniscus flap tear resembling a bucket-handle tear, named a "hemi-bucket-handle" tear; to compare its imaging features with those of a typical bucket-handle tear; and to discuss the potential therapeutic implications of distinguishing these two types of tears.
MATERIALS AND METHODS: Fi... |
1 | Clinical outcome of internal fixation of unstable juvenile osteochondritis dissecans lesions of the knee | Diagnosis and Treatment of Osteochondritis Dissecans AUC | Juvenile osteochondritis dissecans (OCD) lesions of the knee are a common cause of knee pain in skeletally immature patients.The authors sought to determine lesion healing rates, the risk factors associated with failure to heal, and the clinical outcomes for patients who underwent internal fixation for unstable OCD les... |
0 | A comparative study of the transversus abdominis plane (TAP) block efficacy on post-bariatric vs aesthetic abdominoplasty with flank liposuction | Panniculectomy & Abdominoplasty CPG | The transversus abdominis plane (TAP) block acts on the nerves localised in the anterior abdominal wall muscles. We evaluated the efficacy on post-bariatric (PB) patients undergoing body-contouring abdominoplasty. We retrospectively evaluated PB patients undergoing abdominoplasty with flank liposuction and compared res... |
0 | From Pathogenesis to Therapy in Knee Osteoarthritis: Bench-to-Bedside | PRP (Platelet-Rich Plasma) | Osteoarthritis (OA) is currently the most widespread musculoskeletal condition and primarily affects weight-bearing joints such as the knees and hips. Importantly, knee OA remains a multifactorial whole-joint disease, the appearance and progression of which involves the alteration of articular cartilage as well as the ... |
0 | Surgical excision of ununited hook of hamate fractures via the carpal tunnel approach | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | INTRODUCTION: Direct excision of a symptomatic ununited hook of hamate fracture is the gold standard, most frequently via a Guyon space approach. The open carpal tunnel approach is another option, which has not previously been commonly considered and not reported in a peer review journal. Our study aims to highlight th... |
0 | Dietary calcium intake and serum vitamin D are major determinants of bone mass variations in women. A longitudinal study | Management of Hip Fractures in the Elderly | BACKGROUND AND AIMS: Bone mineral density (BMD) is one of the main determinants in the pathogenesis of fractures. However, data on factors predicting longitudinal variations in BMD are still limited and incomplete. Such data would be of great importance in order to better focus prevention strategies in both the clinica... |
1 | Extradural and parenteral pethidine as analgesia after total hip replacement: effects and kinetics. A controlled clinical study | AAHKS (8) Anesthetic Infiltration | Twenty-one patients who had undergone total hip replacement were randomly assigned to one of three groups in order to compare a single dose of 1 mg/kg of pethidine im (I) and 20 mg (II) or 60 mg of extradural pethidine (III) in a double-blind design. The degree of analgesia, the adverse effects, and the kinetics were s... |
0 | Extreme oncoplasty: breast conservation for patients who need mastectomy | Reduction Mammoplasty for Female Breast Hypertrophy | Extreme oncoplasty is a breast conserving operation, using oncoplastic techniques, in a patient who, in most physicians' opinions, requires a mastectomy. These are generally large, greater than 5 cm multifocal or multicentric tumors. Many will have positive lymph nodes. Most will require radiation therapy, even if trea... |
0 | Multidisciplinary team care in rehabilitation: An overview of reviews | Management of Hip Fractures in the Elderly | Objectives: To systematically investigate current scientific evidence about the effectiveness of multidisciplinary team rehabilitation for different health problems. Data sources: A comprehensive literature search was conducted in Cochrane, Medline, DARE, Embase, and Cinahl databases, and research from existing systema... |
1 | Meta-analysis of antibiotic prophylaxis in breast reduction surgery | Reduction Mammoplasty for Female Breast Hypertrophy | BACKGROUND: Breast reduction surgery is a very common procedure; however, there is still no consensus as to whether antibiotics should be used perioperatively.
OBJECTIVE: To review the world literature and perform a meta-analysis of studies comparing wound infection rates with antibiotic use in breast reduction surgery... |
0 | Osteoarthritis patients' perceptions regarding Appropriateness for total joint replacement surgery | Surgical Management of Osteoarthritis of the Knee CPG | Purpose: Appropriateness criteria for hip/knee total joint replacement (TJR) have been based on expert physician opinion and, in general, consider three groups of patient factors: disease severity (pain and functioning, radiographs), capacity to benefit, and willingness (motivation). The objective of our study was to g... |
1 | Operative management of supracondylar humeral fractures in children: Comparison of five fixation methods | Pediatric Supracondylar Humerus Fracture 2020 Review | BACKGROUND: The best method for stabilising supracondylar humeral fractures (SHFs) in children remains unclear. The objective of this study was to compare the outcomes of five different fixation methods for SHFs in children. HYPOTHESIS: Differences in intra-operative and short-term post-operative parameters can be demo... |
0 | Very low rates of hip fracture in Beijing, People's Republic of China the Beijing Osteoporosis Project | Management of Hip Fractures in the Elderly | One third of the world's hip fractures are said to occur in Asia, mostly in China. However, there have as yet been no validated studies of hip fracture rates in China. The authors estimated the incidence of hip fractures in Beijing, People's Republic of China, and took several steps to validate the estimates. All 76 Be... |
0 | Occurrence of post traumatic stress symptoms and their relationship to professional quality of life (ProQoL) in nursing staff at a forensic psychiatric security unit: a cross-sectional study | DoD PRF (Psychosocial RF) | BACKGROUND: Violence is frequent towards nurses in forensic mental health hospitals. Implications of this high risk environment have not been systematically explored. This paper explores occurrence of symptoms on post traumatic stress and their relationship to professional quality of life.
METHODS: Self report question... |
0 | Liposuction and surgical recontouring of the neck: a retrospective analysis | Panniculectomy & Abdominoplasty CPG | BACKGROUND: With the advent of tumescent liposuction, many advances in cosmetic surgery have occurred. Liposuction of excess adipose tissue from the submental area, jowls, and neck, along with cold steel surgery, has become an attractive alternative to the facelift for cervicomental aesthetic surgery. OBJECTIVE: To des... |
1 | Assessment of interleukin-6 and other inflammatory markers in the diagnosis of Egyptian patients with periprosthetic joint infection | PJI DX Updated Search | The orthopedic community continues to struggle for accurate diagnosis of periprosthetic joint infection (PJI) as it is a devastating complication after total joint arthroplasty. There is no universally accepted diagnostic test that is absolute or reliable for detection of PJI. Recent research has raised doubt regarding... |
0 | Prevalence and progression of osteoporosis in patients with COPD: results from the TOwards a Revolution in COPD Health study | Management of Hip Fractures in the Elderly | BACKGROUND: Osteoporosis is common in patients with COPD, but its prevalence and progression are not well characterized. Concerns have been raised over the possible deleterious effect of long-term therapy with inhaled corticosteroids (ICSs) on bone density in this population. Here, we investigated the long-term effects... |
1 | Soccer injuries: a review on incidence and prevention | Anterior Cruciate Ligament Injuries CPG | Several investigators have studied the incidence and causes of soccer injuries in male professional players; however, epidemiological data on injuries in female soccer players are limited. From the data presented, it can be estimated that, on average, every elite male soccer player incurs approximately one performance-... |
1 | Computer assisted alignment of opening wedge high tibial osteotomy provides limited improvement of radiographic outcomes compared to flouroscopic alignment | OAK 3 - Non-arthroplasty tx of OAK | INTRODUCTION: There are numerous methods available to assist surgeons in the accurate correction of varus alignment during medial opening wedge high tibial osteotomy (MOWHTO). Preoperative planning performed with radiographs or more recently intraoperative computer navigation software has been used. The aim of the stud... |
0 | Indirect decompression and reduction of lumbar spondylolisthesis does not result in higher rates of immediate and long term complications | Hip Fx in the Elderly 2019 | Nerve root decompression and spondylolisthesis reduction is typically reserved for open surgery. MIS techniques have been thought to be associated with higher rates of neurological complications. This study aims to report acute and chronic neurologic complications encountered with MIS surgery for spondylolisthesis, spe... |
0 | An overview of the prevalence of 25-hydroxy-vitamin D inadequacy amongst elderly patients with or without fragility fracture in the United Kingdom | Management of Hip Fractures in the Elderly | BACKGROUND: Many studies have investigated the prevalence of 25-hydroxy-vitamin D inadequacy throughout the world and found a high prevalence of 25-hydroxy-vitamin D inadequacy in older patients, particularly those with fragility fracture. SCOPE: To review the findings from vitamin D audits from six units across the UK... |
0 | Osteochondritis dissecans of the knee. A long-term study | Diagnosis and Treatment of Osteochondritis Dissecans AUC | Twenty-two knees with osteochondritis dissecans diagnosed before skeletal maturity were followed prospectively into middle age: 32% had radiographic evidence of moderate or severe osteoarthritis at an average follow-up of 33.6 years; only half had a good or excellent functional result. We found that osteoarthritis was ... |
0 | Mortality after all major types of osteoporotic fracture in men and women: an observational study | Management of Hip Fractures in the Elderly | BACKGROUND: Mortality increases after hip fractures in women and more so in men. Little is known, however, about mortality after other fractures. We investigated the mortality associated with all fracture types in elderly women and men. METHODS: We did a 5-year prospective cohort study in the semi-urban city of Dubbo, ... |
0 | Clinical trial of intra-articular injection of sodium hyaluronate in patients with osteoarthritis of the knee | OAK 3 - Non-arthroplasty tx of OAK | A multiâ?centre randomized, doubleâ?blind, parallelâ?group clinical trial was carried out in 63 patients with osteoarthritis of the knee to compare the efficacy and tolerability of a course of intraâ?articular injections of 20 mg sodium hyaluronate with a similar course of injections of placebo. Treatment consisted... |
0 | Histologic analysis of postmeniscectomy osteonecrosis | AMP (Acute Meniscal Pathology) | Bone marrow signal changes on magnetic resonance imaging (MRI) after meniscectomy have been reported as evidence of postmeniscectomy osteonecrosis, but this pathology is unclear. We conducted a study to follow-up cases with bone marrow signal changes on MRI after meniscectomy and investigate the pathology of underlying... |
0 | Clinical re-evaluation of the relationship between gluteal injuries and embolized arteries in patients with massive hemorrhage following pelvic fracture | DoD SSI (Surgical Site Infections) | PURPOSE: Transcatheter angiographic embolization (TAE) has been widely accepted as a treatment for hemorrhagic shock associated with pelvic fracture. Gluteal muscle necrosis is a rare but potentially fatal complication of TAE. This study aimed to clarify factors associated with safer embolization procedures by evaluati... |
0 | Increased Revision Rates After Total Knee Arthroplasty in Patients Who Smoke | DOD - Acute Comp Syndrome CPG | The purpose of this study was to compare the clinical outcomes of total knee arthroplasty in patients who reported a history of tobacco use with those who were nonsmokers. Between 2006 and 2009, there were 131 total knee arthroplasties performed in patients who were smokers and 490 in patients who did not smoke. At a m... |
0 | Tibial growth plate vascularization is inhibited by the dithiocarbamate pesticide thiram in chickens: potential relationship to peripheral platelet counts alteration | OAK 3 - Non-arthroplasty tx of OAK | The widespread use of thiram has raised concerns for health and its toxic effects, but the underlying toxicity mechanism on platelets and bones is poorly defined. Here, we found a significant increase in the number of platelets in chickens with the thiram intake, due to the increased expression of thrombopoietin mRNA i... |
0 | Structural and symptomatic efficacy of glucosamine and chondroitin in knee osteoarthritis: a comprehensive meta-analysis | SR for PM on OA of All Extremities | OBJECTIVE: To assess the structural and symptomatic efficacy of oral glucosamine sulfate and chondroitin sulfate in knee osteoarthritis through independent meta-analyses of their effects on joint space narrowing, Lequesne Index, Western Ontario MacMaster University Osteoarthritis Index (WOMAC), visual analog scale for ... |
1 | Nerve conduction studies of median motor nerve and median sensory branches according to the severity of carpal tunnel syndrome | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | OBJECTIVE: To evaluate each digital branch of the median sensory nerve and motor nerves to abductor pollicis brevis (APB) and 2nd lumbrical (2L) according to the severity of carpal tunnel syndrome (CTS). METHODS: A prospective study was performed in 67 hands of 41 patients with CTS consisting of mild, 23; moderate, 27;... |
1 | Reduction mammaplasty is effective treatment according to two quality of life instruments. A prospective randomised clinical trial | Reduction Mammoplasty for Female Breast Hypertrophy | PURPOSE: Debate around reduction mammaplasty has continued due to lack of prospective randomised clinical trials (RCTs). Therefore, a prospective randomised clinical trial was designed to assess the effectiveness of reduction mammaplasty performed for symptomatic breast hypertrophy.
PATIENTS AND METHODS: 82 patients we... |
0 | Fat grafting: an alternative or adjunct to facelift surgery? | Panniculectomy & Abdominoplasty CPG | Fat transfer is a cornerstone to managing facial aging and can represent a stand-alone procedure or be used in conjunction with other surgical treatments. Fat can also be used with fillers or as an alternative to fillers both for the benefit of educating surgeons and for improved patient communication to establish clea... |
0 | Third-Generation Medium Cross-Linked Polyethylene Demonstrates Very Low Wear in Total Hip Arthroplasty | DoD SSI (Surgical Site Infections) | Background: Cross-linked polyethylene (XLPE) liners have shown lower wear rates than conventional polyethylene liners in total hip arthroplasty. The primary aim of our study was to report our most recent analysis of wear rates and clinical outcomes of a third-generation XLPE liner. Secondary aims were to investigate th... |
0 | Analgesic Value of Adductor Canal vs Femoral Block After Total Knee Arthroplasty | OAK 3 - Non-arthroplasty tx of OAK | Subjects undergoing total knee arthroplasty will receive a preoperative adductor canal block with continuous catheter. Following a standardized general anesthetic for the procedure, subjects will be asked to rate their pain using the NRSâ?11 pain scale in the recovery room. Once the pain is reported at a 5/10 or above... |
0 | Results of different surgical procedures on total knee arthroplasty infections | Surgical Management of Osteoarthritis of the Knee CPG | Seventy-six consecutive infected total knee arthroplasties in 74 patients were treated between December 1981 and March 1990. The average follow-up period was 57 months (range, 24-121 months). No patients were lost to follow-up evaluation and 12 patients died from unrelated causes. Patients were classified, based on the... |
0 | Results and complications of the low contact stress knee prosthesis | AMP (Acute Meniscal Pathology) | We present the midterm results and complications of 101 low contact stress total knee replacements performed in 94 patients and reviewed at an average follow-up of 5.2 years (range, 4-8 years). The mean age at the time of surgery was 66 years (range, 53-76 years). Meniscal bearings were used in 83 knees and a rotating ... |
0 | Operative management of closed intra-articular fractures of distal end of humerus in adults | Pediatric Supracondylar Humerus Fracture 2020 Review | This is a study of 60 patients with mean age of 30 years having intra-articular fracture of distal humerus of type C (AO classification). We treated these fractures by open reduction and internal fixation through transolecranon approach. Mean duration of operative time with that of injury was 10 days. In all the cases ... |
0 | Treatment of unilateral giant fibroadenoma by breast reduction skin incision: the inverted "T" technique | Reduction Mammoplasty for Female Breast Hypertrophy | BACKGROUND: Giant fibroadenoma (GFA) has been defined as fibroadenoma greater than 5 cm in it's the widest diameter and/or weighing more than 500 g. A benign lesion, its size also raises the possibility of malignancy requiring differentiation from a malignant breast disease. When unilateral GFA presents with a severe b... |
0 | Effectiveness of hip protectors for preventing hip fractures in elderly people: systematic review [with consumer summary] | Management of Hip Fractures in the Elderly | OBJECTIVES: To present the updated results of systematic review of the current evidence for the effectiveness of hip protectors from reports of completed randomised trials, and to explore the evolution of that evidence. DESIGN: Systematic review with meta-analysis. DATA SOURCES: Cochrane Bone, Joint, and Muscle Trauma ... |
1 | Sliding hip screw versus sliding helical blade for intertrochanteric fractures: a propensity score-matched case control study | Hip Fx in the Elderly 2019 | The spiral blade modification of the Dynamic Hip Screw (DHS) was designed for superior biomechanical fixation in the osteoporotic femoral head. Our objective was to compare clinical outcomes and in particular the incidence of loss of fixation. In a series of 197 consecutive patients over the age of 50 years treated wit... |
1 | Early Antibiotic Administration Is Associated with a Reduced Infection Risk When Combined with Primary Wound Closure in Patients with Open Tibia Fractures | DoD SSI (Surgical Site Infections) | BACKGROUND: Early administration of antibiotics and wound coverage have been shown to decrease the deep infection risk in all patients with Type 3 open tibia fractures. However, it is unknown whether early antibiotic administration decreases infection risk in patients with Types 1, 2, and 3A open tibia fractures treate... |
1 | Changing paradigms in lower extremity reconstruction in war-related injuries | DoD SSI (Surgical Site Infections) | BACKGROUND: Ballistic high-energy trauma has substantially increased the severity of non-fatal extremity injuries incurred in modern warfare. Expedient medical care, refinement in surgical techniques, and soft tissue coverage have brought about a paradigm shift in the management of lower extremity wounds during the las... |
0 | Imaging of avascular necrosis of femoral head: familiar methods and newer trends | AAHKS (2) Corticosteroids | Avascular necrosis of the femoral head (AVN) is an increasingly common cause of musculoskeletal disability, and it poses a major diagnostic and therapeutic challenge. Although patients are initially asymptomatic, AVN usually progresses to joint destruction, requiring total hip replacement, usually before the fifth deca... |
0 | In vivo analysis of the isolated posterior cruciate ligament-deficient knee during functional activities | OAK 3 - Non-arthroplasty tx of OAK | BACKGROUND: Most patients with isolated posterior cruciate ligament (PCL) injuries have minimal symptoms, and nonoperative treatment is recommended. However, over time, these patients can develop significant degenerative changes in their knees. Historically, PCL laxity is graded by nonweightbearing anteroposterior meas... |
0 | Vesicoamniotic Shunting Improves Outcomes in a Subset of Prune Belly Syndrome Patients at a Single Tertiary Center | Panniculectomy & Abdominoplasty CPG | Objective: Review outcomes of Prune Belly Syndrome (PBS) with the hypothesis that contemporary management improves mortality. Methods: A retrospective chart review of inpatient and outpatient PBS patients referred between 2000 and 2018 was conducted to assess outcomes at our institution. Data collected included age at ... |
0 | Efficacy and safety of hyaluronic acid in the management of osteoarthritis: Evidence from real-life setting trials and surveys | PJI DX Updated Search | The European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) treatment algorithm recommends intra-articular (IA) hyaluronic acid (HA) for management of knee osteoarthritis (OA) as second-line treatment in patients who remain symptomatic despite use of non-steroidal anti-inflammatory... |
0 | Perioperative optimization of hip fracture patients | Hip Fx in the Elderly 2019 | Hip fractures are the most common cause for admission to an acute orthopaedic ward in the UK, and typically affect elderly, frail individuals with extensive co-morbidity. As such, they are associated with a high burden of morbidity and mortality as well as significant financial cost. Standards have therefore been devel... |
0 | Resource use in general anaesthesia: A comparison of practice in Germany, France and the UK | Surgical Management of Osteoarthritis of the Knee CPG | This study reports the results of a study of anaesthetic resources used before, during and after various surgical procedures performed in the United Kingdom, Germany and France. A total of 1787 patients undergoing general anaesthesia for daycase knee arthroscopy, daycase laparoscopic gynaecological procedures, inpatien... |
0 | Treatment of deep infection of the hip associated with massive bone loss | DoD SSI (Surgical Site Infections) | We have carried out in 24 patients, a two-stage revision arthroplasty of the hip for infection with massive bone loss. We used a custom-made, antibiotic-loaded cement prosthesis as an interim spacer. Fifteen patients had acetabular deficiencies, eight had segmental femoral bone loss and one had a combined defect. There... |
0 | Can widespread hypersensitivity in carpal tunnel syndrome be substantiated if neck and arm pain are absent? | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Recent studies demonstrated that patients with carpal tunnel syndrome (CTS) have signs of thermal and mechanical hyperalgesia in extra-median territories suggesting an involvement of central pain mechanisms. As previous studies included patients with shoulder/arm symptoms or neck pain, a potential influence of these co... |
1 | Comparison of the Efficacy of Different Analgesia Treatments for Total Knee Arthroplasty | AAHKS (9/10) Regional Nerve Blocks | Background and Aim: The severe pain after total knee arthroplasty (TKA) brings many patients more suffering, longer hospital stay, and higher expenses. This study was designed to assess the relative efficacy of several clinical treatments for postoperative analgesia of TKA through network meta-analysis based on multipl... |
0 | Controlled trial of homoeopathic treatment of osteoarthritis | OAK 3 - Non-arthroplasty tx of OAK | In a doubleâ?blind, placeboâ?controlled crossover study to compare the homoeopathic remedy Rhus tox. 6X with fenoprofen in osteoarthritis of the hip and knee, fenoprofen was shown to have beneficial analgesic and antiâ?inflammatory effects which differed significantly from those of placebo. The effects of Rhus tox. ... |
0 | The effect of comorbidities and age on functional outcomes after total knee arthroplasty in the octogenarian: A matched cohort study | OAK 3 - Non-arthroplasty tx of OAK | Introduction: According to the World Health Organization data repository, the average life expectancy at birth for Singapore in 2015 has risen to 83.4 years, and many octogenarians (OG) remain active socioeconomically. The aim of this study is to compare the improvement and the impact of comorbidities on functional rec... |
0 | The Effects of Blood Transfusion on Delirium Incidence | DoD PRF (Psychosocial RF) | Background Both anemia and blood transfusion could be precipitating factors for delirium; hence in postoperative patients with anemia at high risk for delirium, it is controversial whether transfusion is the best option. The aim of this study is to investigate the association of anemia and delirium and the role of bloo... |
0 | Femoral neck fracture in end-stage renal disease treated with osteosynthesis | Management of Hip Fractures in the Elderly | Background: Treatment of femoral neck fracture is well documented in the literature. Femoral neck fractures in patients aged < 65 years are generally treated using closed reduction and internal fixation, while hemiarthroplasty is the treatment of choice for patients > 65 years. In specific populations, such as patients... |
0 | Parathormone, calcitonin, and vitamin D metabolites during normal fracture healing in geriatric patients | Management of Hip Fractures in the Elderly | In order to study the role of calcium-regulating hormones during callus formation in elderly patients, serum levels of parathormone (PTH), calcitonin (CT), 25-hydroxyvitamin D [25-OH-D], 1,25-dihydroxyvitamin D [1,25(OH)2D], 24,25-dihydroxyvitamin D [24,25(OH)2D], and calcium (Ca) were determined in 41 patients with fr... |
0 | BraveMind: advancing the Virtual Iraq/Afghanistan PTSD Exposure Therapy | DoD PRF (Psychosocial RF) | Preâ?Treatment Assessment: Potential subjects will be asked to provide a copy of their DD214 to verify their military service record. Once a potential participant has met all screening inclusion and exclusion criteria and consented to participate, the CAPS will be administered to determine current PTSD status. Randomi... |
0 | Inter-observer agreement of the Wagner, University of Texas and PEDIS classification systems for the diabetic foot syndrome | DoD LSA (Limb Salvage vs Amputation) | BACKGROUND: The aim of this cohort study was to assess the inter-observer agreement of three diabetic foot classification systems: the Wagner, the University of Texas and the PEDIS. METHODS: We included 250 consecutive patients diagnosed of diabetic foot syndrome in 2009-2013. Wound scores were recorded at admission an... |
0 | The effect of lentivirus-mediated SIRT1 gene knockdown in the ATDC5 cell line via inhibition of the Wnt signaling pathway | TO: WNT2 Pathway Modulator | SIRT1 is a highly conserved type III acetyltransferase gene located on chromosome 10 in mammals that belong to the Sirtuins family. In order to explore the effects of the SIRT1 gene in the ATDC5 cell line, an RNAi SIRT1 target sequence was designed and synthesized, aimed to knockdown the expression of SIRT1 in ATDC5 by... |
0 | Ceramic endoprosthesis in total hip arthroplasty | Management of Hip Fractures in the Elderly | Aluminia-on-aluminia hip prosthesis with titanium alloy stem was used in 255 cases, for 143 patients with cemented acetabular cup and 112 with an uncemented screw cup. The average age of the patients was 62 years. Of the patients, 35 were treated bilaterally. The indication for surgery was osteoarthritis in 186 cases, ... |
0 | Costs of hip fracture. Rehabilitation of 180 patients in primary health care | HipFx Supplemental Cost Analysis | Costs related to functional status were calculated for 180 consecutive hip fracture patients (mean age 78 years) who were admitted from their own home and rehabilitated in primary health care. Within 4 months after the fracture, 75 percent of the patients had been discharged to their own home, 9 percent were dead, and ... |
0 | Vascularised knee joint transplantation in man: The first two years experience | AAHKS (2) Corticosteroids | Objective: To describe our early experience with a new technique for restoring destroyed knee joints to give reasonable functional results. Design: Observational clinical trial. Setting: Level-1-Trauma centre, Germany. Subjects: 5 patients with large bone defects of the knee and loss of the extensor apparatus caused ei... |
0 | Efficacy of Kirschner-wires and tension band in hip arthroplasty for aged patients with unstable intertrochanteric osteoporotic fracture: A 2-to-11-year follow-up | Hip Fx in the Elderly 2019 | The aim of this study was to evaluate the efficacy of supplementary fixation in hip arthroplasty with the use of Kirschner-wires and tension band for geriatric patients suffering unstable intertrochanteric osteoporotic fractures. A total of 103 patients aged more than 75 years were recruited. A bipolar or total hip rep... |
0 | Wiring Techniques for the Fixation of Trochanteric Fragments during Bipolar Hemiarthroplasty for Femoral Intertrochanteric Fracture: Clinical Study and Technical Note | Hip Fx in the Elderly 2019 | PURPOSE: Femoral intertrochanteric fractures are common in the elderly. Appropriate surgical fixation of trochanteric fracture fragments can restore normal anatomical structure and ambulation, and can aid in the recovery of biomechanical function of the hip. We evaluated clinical outcomes of bipolar hemiarthroplasty us... |
0 | Management of central breast tumours with immediate reconstruction of the nipple-areola complex; a suggested guide | Reduction Mammoplasty for Female Breast Hypertrophy | BACKGROUND: Breast conserving surgery (BCS) for central breast tumours with immediate reconstruction of the nipple-areola complex (NAC) is a relatively new addition to the surgical palette of the oncoplastic surgeon. Most oncoplastic techniques presented to date have only been suitable for women with large breasts.
MET... |
0 | Total shoulder arthroplasty - arthroplasty for glenohumeral arthropathies: results and complications after a minimum follow-up of 8 years according to the type of arthroplasty and etiology | Glenohumeral Joint OA | INTRODUCTION: Arthroplasty for glenohumeral arthropathies have specific complications and the final results are sometimes more dependent upon the type of shoulder arthroplasty than the initial etiology. The aim of our study was to evaluate the rate of complications and the functional improvement with different types of... |
0 | Case finding for the management of osteoporosis with FRAX--assessment and intervention thresholds for the UK | Management of Hip Fractures in the Elderly | Assessment and intervention thresholds are developed and proposed in men aged over 50 years and postmenopausal women for the UK based on fracture probability from the WHO fracture risk assessment tool (FRAX). INTRODUCTION: The FRAX tool has recently become available to compute the 10-year probability of fractures in me... |
0 | Myeloma bone disease: Pathophysiology and management | MSTS 2018 - Femur Mets and MM | Multiple myeloma bone disease is marked by severe dysfunction of both bone formation and resorption and serves as a model for understanding the regulation of osteoblasts (OBL) and osteoclasts (OCL) in cancer. Myeloma bone lesions are purely osteolytic and are associated with severe and debilitating bone pain, pathologi... |
1 | External skeletal fixation and rectus abdominis free-tissue transfer in the management of severe open fractures of the tibia | DoD LSA (Limb Salvage vs Amputation) | The management of severe open fractures of the tibia remains one of the more challenging problems facing the orthopedic surgeon. Patients who sustain high-energy injuries with loss of soft tissue in conjunction with displaced comminuted fractures face high rates of delayed union, nonunion, infection, and in some instan... |
0 | Arthroscopic hip surgery compared with physiotherapy and activity modification for the treatment of symptomatic femoroacetabular impingement: multicentre randomised controlled trial | Developmental Dysplasia of the Hip 2020 Review | Objective To compare arthroscopic hip surgery with physiotherapy and activity modification for improving patient reported outcome measures in patients with symptomatic femoroacetabular impingement (FAI). Design Two group parallel, assessor blinded, pragmatic randomised controlled trial. Setting Secondary and tertiary c... |
0 | Arthroscopy in the diagnostics and treatment of non-acute knee disorders in children | Diagnosis and Treatment of Osteochondritis Dissecans AUC | 199 arthroscopies were performed on children with non-acute knee problems during 1985-1992 at the University Hospital of Oulu (76 boys and 123 girls). The mean age was 13 (2-15) years. The ratio between boys and girls was 1:1.6 showing the incidence among girls to be greater. The mean duration of symptoms was 16 (0.3-9... |
0 | Inhibition of PGE2 in Subchondral Bone Attenuates Osteoarthritis | AMP (Acute Meniscal Pathology) | Aberrant subchondral bone architecture is a crucial driver of the pathological progression of osteoarthritis, coupled with increased sensory innervation. The sensory PGE2/EP4 pathway is involved in the regulation of bone mass accrual by the induction of differentiation of mesenchymal stromal cells. This study aimed to ... |
0 | The stiff total knee replacement: Evaluation and treatment | Surgical Management of Osteoarthritis of the Knee CPG | Stiffness after TKR is a frustrating complication that has many possible causes. Though the definition of stiffness has changed over the years, most would agree that knee flexion of less than 75(degrees) and a 15(degrees) lack of extension constitutes stiffness. This presentation will focus on the potential causes of a... |
0 | Is distal locking with IMHN necessary in every pertrochanteric fracture? | Management of Hip Fractures in the Elderly | Two groups of patients were treated for pertrochanteric fractures (AO/ASIF 31A1+A2) with an intramedullary hip nail. In the first group of 44 patients distal dynamic locking was used, and in the second group of 74 patients the nail was not distally locked. Comparison of the two groups of patients did not show any diffe... |
0 | Charcot-Marie-Tooth disease type 1A: clinicopathological correlations in 24 patients | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | We examined nerve biopsies from 24 patients with Charcot-Marie-Tooth disease type 1A (CMT1A) and proven 17p11.2-12 duplication. There were seven males and 17 females with a mean age of 27.85 +/- 18.95 years at the time of nerve biopsy. A family history consistent with dominant inheritance was present in 17 patients. Cl... |
1 | Comparison of outcomes of untreated carpal tunnel syndrome and asymptomatic controls in meat packers | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Our objectives were to determine the reporting of symptoms, the medical outcome and the work status of meat plant workers diagnosed with clinical carpal tunnel syndrome (CTS). Forty-seven cases of CTS were identified from a previously reported study, and were matched by age, gender and hand use. Cases and controls were... |
0 | Characterization of articular cartilage by combining microscopic analysis with a fibril-reinforced finite-element model | Glenohumeral Joint OA | Load-bearing characteristics of articular cartilage are impaired during tissue degeneration. Quantitative microscopy enables in vitro investigation of cartilage structure but determination of tissue functional properties necessitates experimental mechanical testing. The fibril-reinforced poroviscoelastic (FRPVE) model ... |
0 | Dimethylarginine dimethylaminohydrolase 2, a newly identified mitochondrial protein modulating nitric oxide synthesis in normal human chondrocytes | OAK 3 - Non-arthroplasty tx of OAK | OBJECTIVE: The mitochondrion is known to be important to chondrocyte survival. This study was undertaken to analyze protein expression profiles in chondrocyte mitochondria that are affected by interleukin-1beta (IL-1beta).
METHODS: Normal human chondrocytes were isolated from knee cartilage obtained at autopsy from sub... |
0 | The Vitamin D Analog, MART-10, Attenuates Triple Negative Breast Cancer Cells Metastatic Potential | MSTS 2018 - Femur Mets and MM | Regarding breast cancer treatment, triple negative breast cancer (TNBC) is a difficult issue. Most TNBC patients die of cancer metastasis. Thus, to develop a new regimen to attenuate TNBC metastatic potential is urgently needed. MART-10 (19-nor-2alpha-(3-hydroxypropyl)-1alpha,25(OH)2D3), the newly-synthesized 1alpha,25... |
0 | Systemic doxycycline administration in the treatment of periodontal infections (I). Effect on the subgingival microbiota | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | Systemic doxycycline is one of the more common antimicrobial agents used in the treatment of periodontal infections and yet little is known of its effect on subgingival plaque composition during and after its administration. The purpose of the present investigation was to evaluate changes in subgingival plaque composit... |
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