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Newly married couple comes to OPD for preconception counselling . Both husband and wife are achondroplastic dwarfs. Which of the following should NOT be counselled to the couple?
[ "Intelligence of the child is not affected", "Delivery would most likely require C-section", "There is a 50 % chance of baby having normal stature", "Inheritence is autosomal dominant" ]
C
Achondroplasia: Autosomal dominant inheritance, intelligence is typically normal. Most common non lethal skeletal dysplasia. 98 percent of cases are due to a specific point mutation in the FGFR3 gene 80 percent of cases result from a new mutation Characterized by long bone shoening that is predominantly rhizomelic, an ...
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Platelets transfusion must be completed in how many hours after entering the bag
[ "1 hour", "2 hour", "3 hour", "4 hour" ]
D
Answer- D. 4 hour Once the blood bag is opened hy puncturing one of the sealed pos, the platelets must be administered within 4 hours
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The main mechanism of hyperpyrexia induced by atropine is?
[ "Vasodilation", "inhibition of sweating", "Through central actions", "Increase in basal metabolic rate" ]
B
Ref:KD Tripathi pharmacology 7th edition (page.no: 115) Rise in body temperature by Atropine occurs at higher doses. It is due to both inhibition of sweating as well as stimulation of temperature regulating centre in the hypothalamus.
train
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Wisdom tooth erupts at which age -
[ "6-8 years", "10-12 years", "12-15 years", "17-20 years" ]
D
Ans. is 'd' i.e., 17-20 years o Wisdom teeth are permanent third molarsEruption of temporary teeth(Primary dentition)ToothAge in range (months)Average age (months)Lower CI6-87Upper CI7-98Uppler LI7-98Lower LI10-12111 molar12-1413Canine17-1817[?]5II molar20-3025 Eruption of permanent teeth(Secondary dentition) Age in ra...
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Bupivacaine toxicity leads to?
[ "Cardiac toxicity", "Neural toxicity", "Renal toxicity", "Hepatic toxicity" ]
A
Ans. is 'a' i.e., Cardiac toxicity * Bupivacaine is the most cardiotoxic local anesthetic.* Has been explained in previous sessions.
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In AIDS, lymphadenopathy is most often due to ?
[ "TB", "Lymphoma", "Non specific enlargement of lymph node", "Kaposi's sarcoma" ]
C
Answer is 'c' i.e. Non specific enlargement of lymph node In AIDS, the lymphadenopathy is most often due to the chronic non specific lymphadenitis producing follicular hyperplasia.
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All the muscles of the face are supplied by facial nerve except :
[ "Levator anguli oris", "Corrugator supercilli", "Leavator palpebrae superioris", "Risorius" ]
C
C i.e. Levator palpebrae superioris
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A 38-year-old woman presents with painless post-coital bleeding. She had a cone biopsy for carcinoma in situ five years ago. Her last pap smear was three months after the biopsy. Her last period was six weeks ago. Most probable diagnosis is
[ "Carcinoma of cervix", "Ectopic pregnancy", "Endometrial carcinoma", "Uterine fibroids" ]
A
The recurrence of abnormal vaginal bleeding in a patient with a previous history of a cone biopsy would raise concerns of carcinoma of the cervix.Her last smear was nearly five years ago, indicating she defaulted from follow-up after her cone biopsy.Six weeks amenorrhoea might raise concerns about an ectopic pregnancy ...
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An eye surgery was performed using propofol as the intravenous anaesthetic agent succinylcholine as the muscle relaxant. Recovery from anaesthesia was uneventful. However the patient complains of pain in the muscles. Which of the following is thelikely reason for this?
[ "Propofol", "succinylcholine", "Muscle infarction", "None of the above" ]
B
Succinylcholine is the depolarising muscle relaxant. It causes fasciculations that causes muscle pains(myalgia,muscle weakness)
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Bonds in cellulose that make it resistant to digestion is:
[ "b1-4", "a1-6", "b1-6", "a1-6" ]
A
Cellulose is the chief constituent of plant cell walls. It is insoluble and consists of b-D -glucopyranose units linked by b,1-4 bonds to form long, straight chains strengthened by cross-linking hydrogen bonds. Mammals lack any enzyme that hydrolyzes the b1 -4 bonds, and so cannot digest cellulose. Ref: Harper 28th edi...
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A patient presented with shock and suspecting it due to hypoglycemia. The treatment should be based on-
[ "IV glucose after clinical assessment", "Urine sugar", "Blood sugar", "TV access" ]
C
Severe hypoglycemia, or insulin shock, is a serious health risk for anyone with diabetes. Also called insulin reaction, as a consequence of too much insulin, it can occur anytime there is an imbalance between the insulin in your system, the amount of food you eat, or your level of physical activity . Ref Davidson 23rd ...
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All are true regarding diphtheria toxin except
[ "Toxins blocks elongation of protein", "Beta lysogenic strain produces toxin", "Iron is critical for toxin production", "Toxic is necessary for local wound infection" ]
D
Virulent strains of diphtheria bacilli produce a very powerful exotoxin. The pathogenic effects of the bacillus are due to the toxin. Almost all strains of gravis and intermedius are toxigenic. The toxin is extremely potent and the lethal dose for a 250 g guinea pig is 0.0001g. The toxin has a special affinity for ceai...
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True about H. Pylori is all except -
[ "It splits urea & produces ammonia to survive", "Produces Gastric Ca", "Gram -ye curved rods", "Cag-A gene is not associated with-risk of duodenal ulcer" ]
D
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All are features of a normally decomposed body except -
[ "Greenish discoloration of skin over caecum", "Blisters over skin", "Mummification", "Small miliary skin granules" ]
C
Mummification is not seen in a normally decomposed body. Mummification is a modification of putrefaction and occurs in conditions specially suited for it.
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Heterophile agglutination test is?
[ "Heterophile antibody that reacts with the microorganism or cells of unrelated species due to common antigen sharing.", "Test is performed in hypertonic saline (5%saline) or albumin saline.", "Coomb, Mourant and Race devised a reagent: Rabbit anti-human gamma globulin.", "Helps to detect the blood group and f...
A
Ans. A. Heterophile antibody that reacts with the microorganism or cells of unrelated species due to common antigen sharing.Heterophile antibody: An antibody that reacts with the microorganism or cells of unrelated species due to common antigen sharing. e.g. Weil Felix test, Monospot test.
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Semen analysis of a patient is given below. Where is the site of block, if there is Azoospermia Normal semen volume Fructose present
[ "Testicular", "Below level of seminal vesicles", "Above level of seminal vesicles", "Pituitary" ]
C
null
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Salt and Pepper pot appearance of skull seen in:
[ "Hyperparathyroidism", "Multiple myeloma", "Hypehyroidism", "Pseudo hyperparathyroidism" ]
A
* Pepperpot skull is occasionally used in place of salt and pepper skull to describe the typical radiographic appearance of multiple small radiolucent lesions of the skull vault. * In primary hyperparathyroidism, extensive resorption bone in the skull in combination with cystic areas of osteopenia are termed pepper pot...
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Absolute contraindication for IVP is:
[ "Idiosyncrasy to iodine", "Multiple myeloma", "Raised blood urea", "All of the above" ]
A
Ans. Idiosyncrasy to iodine
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A 28 year old male presented to you with lower abdominal pain associated with pain in the groin. He also complains of nausea. Elevation of the testis relieves his pain. What is your diagnosis?
[ "Ureteric colic", "Prostatitis", "Epididymo orchitis", "Torsion of testis" ]
C
Here since elevation of testis decreases the pain, it is a case of Epididymo orchitis and manipulation surgery should be performed at the earliest to keep the testis ble. In Torsion testis the pain increseas on elevation of the testis. In prostatitis pain occurs on performing a digital rectal examination. Ref: Bailey, ...
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True about polio:
[ "Paralytic polio is most common", "Spastic paralysis seen", "IM injections and increased muscular activity lead to increased paralysis", "Polio drops in pulse polio immunisation given only in <3 years old children" ]
C
False 90-95% of polio infections are asymptomatic False Acute flaccid paralysis is seen in Polio & not spastic paralysis True Risk of paralytic polio is increased by tonsillectomy, strenous physical exercise, tooth extraction,Injection (intramuscular) False OPV drops are given to all children less than 5 yr age in puls...
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All of the following are true about erythema infectiosum EXCEPT?
[ "Slapped cheek appearance seen", "Caused by parvovirus", "Rash initially appears on trunk", "Known as 'fifth disease'" ]
C
Erythema infectiosum (fifth disease) A benign, self-limited exanthematous illness of childhood, caused by Parvovirus B19 Hallmark is the characteristic rash ("slapped-cheek" appearance).
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Pulmonary artery pressure is-
[ "120/80 mm Hg", "25/0 mm Hg", "25/8 mm Hg", "120/0 mm Hg" ]
C
Ans. is 'c' i.e., 25/8 mm Hg Pressures in various portions of CVSo Right ventricle-25/0 mm Hg (systolic/diastolic)o Left ventricle-120/0 mm Hgo Right atrium-2 mm Hgo Left atrium-5mmHgo Aorta-120/80 mm Hgo Pulmonary artery-25/8 mm Hg
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True about diphtheria is
[ "Capsulated bacteria causes infection", "Ratio of carriers and clinical cases is one", "Gram positive and motile", "Lysogenic phase causes disease" ]
D
The toxigenicity of the diphtheria bacillus depends on the presence of corynephages(tox+) in it which acts as the genetic determinant controlling toxin production. Non-toxigenic strains may be rendered toxigenic by infecting them with the beta or some other phage. This is known as lysogenic or phage conversion. The tox...
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Oro-oculo-genital syndrome occurs due to
[ "Vit. A deficiency", "Vit. B1 deficiency", "Vit. B2 dificiency", "Nicotininc acid dificiency" ]
C
null
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Uremia is not associated with hypeension in which of the following situations?
[ "Renal polyaeritis nodosa", "Narrowing of the renal aery", "Renal amyloidosis", "Hyperplastic aeriolar nephrosclerosis" ]
C
Option A: Polyaeritis Nodosa- Renal Aery aneurysm | Decrease Blood supply to kidney | | GFR | Stimulate RAAS: | Renin (High Renin HTN) Option B: Narrow Renal aery- | Blood supply to kidney | | GFR- stimulate RAAS= | Renal HTN Option C: Renal Amyloidosis- B/L Enlarged Kidneys & present With Nephrotic range proteinuria w...
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The commonest cause of acute pancreatitis is -
[ "Biliary calculi", "Alcohol abuse", "Infective", "Idiopathic" ]
A
null
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H1N1 strain of influenza is responsible for-
[ "Avian influenza", "Bird flu", "Swine flu", "None of the above" ]
C
Ans. is 'c' i.e., Swine flu * Swine flu, also called swine influenza, or pig influenza, is caused by influenza virus.* Incubation period is about 1-3 days and the symptoms of swine flu in humans are similar to most influenza infections, e.g. fever, cough, rhinorrhea, fatigue and headache.* Swine flu is most commonly ca...
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Chromosome mutation can by detected all, except:
[ "Single stranded confirmation polymorphism", "Di deoxy chain termination method", "Agarose gel electrophoresis", "Denaturing gradient gel electrophoresis" ]
C
. Agarose gel electrophoresis
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Fejereskov and Thylstrup index is used for
[ "Caries Index in primary teeth", "Index to measure Fluorosis", "Gingival Bleeding Index", "Periodontal Index" ]
B
null
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Which type of osteogenesis imperfecta is also known as imperfecta with blue sclera?
[ "Type 1", "Type 2", "Type 3", "Type 4" ]
A
Clinical types of osteogenesis imperfecta: Osteogenesis imperfecta, type I   Osteogenesis imperfecta tarda  Osteogenesis imperfecta with blue sclerae  Osteogenesis imperfecta congenital; type II Osteogenesis imperfecta congenital, neonatal lethal Vrolik type of osteogenesis imperfecta Osteogenesis imperfecta, pr...
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Functional basis of ionising radiation depends on:
[ "Functional basis of ionising radiation depends on:", "Removal of orbital electron", "Linear energy transfer", "Adding orbital electron" ]
B
B i.e. Removing orbital electrons
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The diagnostic feature of congenital diaphragmatic hernia on prenatal ultrasonography is:
[ "A cyst behind the left atrium", "Mediastinal shift with normal hea axis", "Peristalsis in the thoracic cavity", "Abnormal large abdominal circumference" ]
C
Congenital diaphragmatic hernia are left-sided and posterior in 90 percent, and the most common sonographic finding is repositioning of the hea to the middle or right side of the thorax by the stomach and bowel. With improved technology, visualization of the liver within the thorax is increasingly common. Associated fi...
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Stimulation of Gastric Acid Secretion is done by all EXCEPT
[ "Histamine", "Prostaglandin", "Gastric distension", "Gastrin" ]
B
(B) Prostaglandin # Basic Factors Stimulating GASTRIC SECRETION are Acetylcholine, Gastrin, and Histamine.> Acetylcholine released by parasympathetic stimulation excites secretion of pepsinogen by peptic cells, hydrochloric acid by parietal cells, and mucus by mucous cells.> In comparison, both gastrin and histamine st...
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Endolymph in ear equivalent to
[ "ICF", "Lymph", "CSF", "Blood" ]
A
The inner ear (labyrinth) is made up of two pas, one within the other. The bony labyrinth is a series of channels in the Petros poion of the temporal bone. Inside these channels, surrounded by a fluid called perilymph, is the membranous labyrinth. This membranous structure more or less duplicates the shape of the bony ...
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The protective titre of antitoxin to diphtheria following vaccination is
[ "0.01 IU/ml", "0.05 IU/ml", "0.1 IU/ml", "0.5 IU/ml" ]
A
Active immunization by vaccination with diphtheria toxoid is the key in preventing diphtheria. . Serum antitoxin concentration of 0.01 IU/mL is usually accepted as the minimum protective level. 0.01 IU/mL is considered to provide basic protection and 0.1 IU/ml is considered to provide complete or total protection.
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Which is not produced enteroendocrinally
[ "Intrinsic factor", "Secretin", "Motilin", "GIP" ]
A
Enteroendocrinal cells are the hormone secreting cells present in the glands or mucosa of the GIT particularly stomach & intestine. The enteroendocrinal cells present in gastric glands are G cells- secrete gastrin Enterochromaffin (EC) cells- secrete serotonin Enterochromaffin like (ECL) cells- secrete histamine
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Granular deposition of IgA at dermal papillae on immunofluorescence is seen in:
[ "Herpes gestationalis", "Dermatitis herpetiformis", "Bullous pemphigoid", "IgA dermatosis of childhood" ]
B
Ans. b. Dermatitis herpetiformis Granular deposition of IgA at dermal papillae on immunofluorescence is seen in dermatitis herpetiformis.Dermatitis Herpetiformis: Diagnosis is confirmed by direct immunofluorescence microscopy of normal appearing or faintly erythematous perilesional skin (adjacent to active lesion), by ...
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Paramyxoviruses enters the body ?
[ "Blood", "Respiratory route", "Conjunctiva", "Fecal-oral route" ]
B
Ans. is 'b' i.e., Respiratory route Myxoviruses Myxoviruses are enveloped RNA viruses. They are characterized by ability to adsorb on to mucoprotein (affinity for mucin) on erythrocytes causing agglutination of erythocytes.
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Endemic disease is defined as -
[ "Disease occuring regularly in expected frequency", "Disease occuring irregularly", "Disease occuring in excess of expected freqency", "Disease affecting a large population" ]
A
Ans. is 'a' i.e., Disease occuring regularly in expected frequency Sporadic - Disease occuring irregularly from time to time.Endemic - Disease occuring regularly in expected frequency.Epidemic - Disease occuring in excess of expected frequency.Pandemic - Epidemic affecting a large proportion of population over a wide g...
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Cranial Nerve VIII exits through which of the following ?
[ "Foramen ovale", "Foramen rotundum", "Internal accoustic meatus", "Stylomastoid foramen" ]
C
The Vestibulocochlear nerve emerges from the brain at the cerebellopontine angle and exits the cranium the internal acoustic meatus of the temporal bone. Within the distal aspect of the internal acoustic meatus, the vestibulocochlear nerve splits, forming the vestibular nerve and the cochlear nerve . Ref - Sciencedirec...
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Goniometer is used for :
[ "Amount of vaginal secretions", "To measure width of genital hiatus", "Gonococcal colony count", "Urethrovesical Angle" ]
D
Goniometer It is used to measure baseline urethral angle and maximum strain angle of urethra with a cotton tip swab in place The bladder forms an angle of 100 degree with posterior urethral wall which is also responsible for maintaining urinary continence Ref: Berek and Novak's Gynecology; 15th edition; Chapter 27
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Trendelenberg test is positive in palsy of
[ "Gluteus maximus", "Gluteus medius", "Rectus femoris", "Vastus medialis" ]
B
Ans. is 'b' i.e., Gluteus medius Trendelenberg test : It tests the stability of the hip and paicularly of the abductor mechanism of the limb on which the patient is standing. Principle of the test : Normally when one leg is raised from the ground the pelvis tilts upwaras on that side, through the action of the hip abdu...
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Protractor of scapula is?
[ "Serratus anterior", "Rhomboidis major", "Deltoid", "Pectoralis major" ]
A
Serratus anteriorREF: Gray's anatomy 39th ed p. 829, 830Movements of scapula:MovementMusclesElevationTrapezius and Levator scapularProtractionSerratous anterior and Pectoralis minorRetractionRhomboids and TrapeziusLateral rotationupper trapezius and lower serratousMedial rotationLevator scapulae , Rhomboids and Pectora...
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A 40 year old lady with breast cancer has undergone MRM and is on Tamoxifen for 1 year. She now has presents with bleeding per vaginum 4-5 times. What is the probable cause:
[ "Bleeding disorder", "Endometrial cancer", "Ovarian cancer", "Cervical cancer" ]
B
Ans. (b) Endometrial cancerRef: KDT 6th ed. / 304-5* Tamoxifen is selective estrogen receptor modulator (SERM).* It is having agonistic activity at uterine endometrium.Action of TamoxifenAgonistic activityAntagonistic activityUterus: causes proliferation of endometrium - can cause vaginal bleeding as seen in the caseBr...
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A 40-year-old patient is diagnosed with a localized 1 cm infiltrating ductal cancer after a needle core biopsy of the lesion. She is clinical node negative; a lumpectomy and sentinel lymph node biopsy are performed. The patient develops an anaphylactic response during the case. Which of the following substances was the...
[ "Fluorescein", "99 Tc radiolabeled colloid", "Isosulfan blue dye", "Methylene blue dye" ]
C
Both methylene blue or isosulfan (lymphazurin) blue dye can be used for sentinel lymph node identification and have been associated with some allergic reactions. Isosulfan blue has been associated with rare anaphylactic reactions in <1% of patients. Methylene blue can cause skin necrosis if injected too superficially. ...
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A baby girl presents with bilateral inguinal masses, thought to be hernias but are found to be testes in the inguinal canals.Which karyoty pe would you expect to find in the child - (AIIMS Nov 04)
[ "46. XX", "46.XY", "47,XXY", "47,XYY" ]
B
Ans. is 'b' i.e., 46, XY o Presence of abdominal or inguinal testis suggests testicular feminisation syndrome.o The characteristic features of these disorders are that they are genotypically male (AT) while phenotypically they are female.o These cases usually present as female with abdominal testis.Prepubertal children...
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Osteogenesis imperfecta is due to defect in?
[ "Type I collagen", "Type II collagen", "Type II collagen", "Type IV collagen" ]
A
Osteogenesis imperfecta is due to qualitatively or quantitatively abnormal type I collagen.
train
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Trans-Cervical Endometrial Resection (TCER) is used in A/E :
[ "Endometriosis", "DUB", "Carcinoma endometrium", "Submucous fibroid" ]
B
Ans. is b i.e. DUB Transcervical endometrial resection (Hysteroscopic endometrial ablation) is a technique for management of DUB. Aim of the procedure is to produce a therapeutic Asherman's syndrome and produce amenorrhea. It destroys the endometrium --4 formation of synchea Asherman syndrome --) amenorrhea. It is esse...
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Genital infection in females presenting with thick curdy or flaky discharge may be: March 2004
[ "Candidiasis", "Trichomoniasis", "Syphilis", "Gonorrhoea" ]
A
Ans. A i.e. Candidiasis
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A 24-year-old woman presents to the emergency department with symptoms of fever, chills and rigors. On physical examination, she looks unwell; the temperature is 39.4degC, blood pressure 100/60 mm Hg, pulse 110/min, and oxygen saturation 95%. There is a 3/6 pansystolic murmur at the right sternal border, which increase...
[ "septic emboli", "cardiac failure with prerenal azotemia", "a high level of circulating immune complexes", "fungal disease" ]
C
Glomerulonephritis, arthritis, and many of the mucocutaneous lesions are secondary to circulating immune complexes. The clinical manifestations of infective endocarditis are a result of three factors: (1) direct infection in the heart, (2) septic emboli, and (3) high levels of circulating immune complexes. Renal emboli...
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The blood-air barrier consists of all of the following Except
[ "Alveolar pores", "A layer of surfactant", "Type I alveolar cell cytoplasm", "Fused basal lamina of alveolar and endothelial cells" ]
A
Alveolar pores connect neighboring alveoli and function in equalizing pressure in the alveoli and enable collateral circulation of air. They do not constitute pa of the blood-air barrier.
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In thyroglossal cyst, carcinoma which arises is -
[ "Follicular", "Medullary", "Papillary", "Anaplastic" ]
C
null
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Which of the following is not true about resuscitation in burns patient?
[ "Ringers lactate is the preferred crystalloid solution", "Fluid shift from intravascular to extravascular compartment in the burns patient is maximum in the first 24 hrs", "Quantity of crystalloid needed is calculated using the parkland formula - 6m/Kg body weight per % of the total body surface area burnt", ...
C
Ans. is 'c' i.e., Quantity of crystalloid needed is calculated using the parkland formula-6m/Kg body weight per % of the total body surface area burnt * Proper fluid management is critical to survival in a burn patient.* The hypovolemic shock in burn patient is special in the sense that the total body water remains unc...
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During examination in injury, hair bulbs are crushed. The probable type of wound is
[ "Abrasion", "Laceration", "Stab injury", "Incision" ]
B
HAIR BULBS ARE CRUSHED IN LACERATION Laceration - is the tearing of skin or muscles or mucous membrane caused by a shearing or a crushing force, and produced by application of a blunt force to a broad area of the body. - If the blunt force produces extensive bruising and laceration of deeper tissue, it is called crush ...
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Cause of "bloody" vomitus in a neonate -
[ "Meckel's diveiculum", "Intussusception", "Malrotation", "None" ]
D
Ans. is None Causes of bloody vomitus in neonates --> Stress gastritis, Hemarrhagic disease of newborn, Swallowed maternal blood
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Eruption of Mandibular Central incisor occur at
[ "8-9 years", "6 years", "19-20 years", "15-16 years" ]
B
null
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Most fulminant fungal meningitis is caused by -
[ "Coccidioides", "Histoplasma", "Cryptococcus", "Mucormycosis" ]
C
null
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Law under oath is not necessary in -
[ "Wound ceificate", "Medical ceificate", "Postmoem ceificate", "Expe opinion expressed in a treatise" ]
D
Law under oath is not necessary in expe opinion expressed in a treatise Ref:synopsis of forensic medicine (Dr.K.S.Narayan Reddy), pg no:9,28th edition.
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The most common cause of seizures in a patient of AIDS is
[ "Toxoplasmosis", "Cryptococcal meningitis", "Progressive multifocal leucoencephalopathy", "CNS lymphoma" ]
A
Ans. is 'a' i.e., Toxoplasmosis Neurological manifestations of H.I.V. AIDS dementia complex (HIV encephalopathy) is a result of direct effects of HIV on CNS (not an oppounistic disease). It is subcoical dementia. Most common cause of seizures --> Toxoplasma Most common cause of meningitis --> Cryptococcus M.C. cause of...
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In a Pt. with head injury, unexplained hypotension warrants evaluation of :
[ "Upper cervical spine", "Lower cervical spine", "Thoracic spine", "All" ]
B
B i.e. Lower cervical spine In a patient unconscious from a head injury, or facial trauma a fracture cervical spine should be assumed untill proven otherwiseQ. Lower cervical spine fractures and dislocations are more common in incidence and are more commonly associated with spinal cord damage in comparison to upper cer...
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Which of the following manifestation of rheumatic fever disappears completely ?
[ "Carditis", "Arthritis", "Chorea", "Subcutaneous nodules" ]
B
There is no residual damage in the joint affected by rheumatic arthritis and there is complete resolution.
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Cystine is formed from
[ "Arginine", "Histidine", "Cysteine", "Alanine" ]
C
The difference in structure of cysteine and cystine. Two molecules of cysteine are joined together by S--S bond to form one molecule of cystine.Ref: M.N. Chatterjea - Textbook of Biochemistry, 8th edition, page no: 504
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Which of the following is not seen in Von-gierke's disease?
[ "Type lb has defective translocase", "Patients may present with hypoglycemia and lactic acidosis in the neonatal period", "Easy bruising and epistaxis can be seen", "Hyperuricemia is not seen" ]
D
Ans. is 'd' i.e., Hyperuricemia is not seen Type I glycogen storage disease (glucose-6-phosphatase or translocase deficiency, von Gierke's disease)* Type I glycogen storage disease is an autosomal recessive disorder caused by glucose-6-phosphatase deficiency in liver, kidney, and intestinal mucosa.* There are two subty...
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A study under Australian collaborative trial on steroids use in neonates was done. Which of the following is true –
[ "No difference between placebo & corticosteroid", "Corticosteroid to children causes behavioural worsening", "Corticosteroid to children causes reduction in head circumference", "Corticosteroid to children causes neuro sensitivity degradation" ]
B
The Australian Collaborative Trial of Repeat Dose of Steroids (ACTORDS) conducted as multicentre RCT, in Austra­lia and New Zealand by Crowther, v and colleagues enrolled 982 pregnant women less than 32 weeks to receive either single dose of intramuscular Betamethasone or saline placebo weekly till 32 weeks of gestatio...
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Ipsilateral Homogeneous opacification and contralateral mediastinal shift is seen in
[ "Collapse", "Consolidation", "Hydrothorax", "Hemothorax" ]
C
null
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Thickness of lead apron is
[ "0.25 mm", "0.3 mm", "0.4 mm", "0.5 mm" ]
D
Thickness of lead apron is 0.5 mm.
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Increased thickness of granular layer is found in
[ "Psoriasis", "Lichen planus", "Ecthyma gangreosum", "Intertigo" ]
B
Hypergranulosis is seen in Lichen planus whereas Psariosis is characterized by absent granular layer.
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Absolute contraindications for HSG are all except
[ "Pregnancy", "Pelvic inflammatory disease", "Mullerian anomalies", "Genital tuberculosis" ]
C
Absolute contraindication for HSG are Genital TB Pelvic inflammatory disease Pregnancy Allergy to dye.
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Hill-Sachs lesion in recurrent shoulder dislocation is
[ "Injury to humeral head", "Rupture of tendon of supraspinatus muscle", "Avulsion of glenoid labrum", "None of the above" ]
A
A i.e. Injury to humeral head
train
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Clue cells are seen in: (REPEAT 2013)
[ "Bacterial vaginosis", "Moniliasis", "Trichomoniasis", "All of the above" ]
A
Ans: A (Bacterial vaginosis) Ref: Shaw's Textbook of Gynecology 15 th edition pg.131 Explanation: GARDNERELLA VAGINOSIS Alteration in normal vaginal flora A decrease in number of lactobacilli in vaginal discharge - lactobacilli reduce pH and release hydrogen peroxide toxic to other bacteria 100 fold increase in anaerob...
train
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Muscle relaxant contraindicated in Renal failure is –
[ "Gallamine", "d-TC", "Vecuronium", "Atracurium" ]
A
null
train
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Strenuous exercise is not done in this glycogen storage disease:
[ "McArdle disease", "Anderson disease", "Pompe disease", "Von Gierke disease" ]
A
Ans. A. McArdle disease* McArdle disease is an AR condition, one of the type V glycogen storage disease.* Enzyme deficient: Myophosphorylase enzyme* Due to enzyme deficiency there is inability to breakdown the muscle glycogen and prevents lactate production.* Patients usually complain of exercise intolerance and muscle...
train
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Which of the following stain is used to assess tear film integrity:-
[ "Congo red", "Alcian Blue", "Rose bengal", "All of the above" ]
C
Tests for Tear Film and Epithelial Integrity Stains used commonly : -Fluorescein -Rose Bengal -Lissamine green -Rhodhamine Blue Fluorescein Stains exposed basement membrane Stains cornea more than conjunctiva. For diagnosing Filamentary keratitis, measuring TBUT CORNEAL STAINING OF DRY EYE USING FLUORESCEIN STAINING CO...
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5 year old child comes to hospital with history of loose stools but no history of fever or blood in stools. Mother says he is irritable and drinks water if given. On examination eyes sunken and on skin pinch test the skin is retracted within two seconds but not immediately. What will be the appropriate management?
[ "Administer first due of i.v antibiotic and immediately refer to higher centre", "Give oral antibiotics and ORS and ask the mother to continue the same and visit next day", "Consider severe dehydration, start i.v fluids, antibiotics and refer to higher centre", "ORS with zinc for 14 days" ]
D
This child has acute diarrhoea with same dehydration. So, treatment is ORS with zinc for 14 days.
train
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Endodontic surgical triad does not include:
[ "Magnification.", "Patients compliance.", "Illumination.", "Instruments." ]
B
Endodontic surgical triad Magnification Illumination. Instruments.
train
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Regarding xenon all are true except
[ "Inhalational anaesthetic agent with lower blood- gas partition coefficient", "Attains lower alveolar concentration", "Faster induction and recovery", "Least soluble anaesthetic agent in blood." ]
B
Since xenon has lower blood gas partition coefficient, it attains higher alveolar concentration.
train
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Venturi meter is used for –
[ "Measuring amount required for chlorination", "Measuring air velocity", "Measuring bed strength in slow sand filter", "Measuring dissolving capacity of gas" ]
C
null
train
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Wimburger sign is seen in ?
[ "Scurvy", "Rickets", "Osteoporosis", "Osteomalacia" ]
A
Ans. is 'a' i.e., Scurvy Radiological features of scurvy The typical radiological features occur at the ends of long bones, paicularly around knee, i.e. lower end of femur and upper end of tibia. Other common site is proximal end of humerus. Features are - Ground glass appearace of bone Pencil thin coex White line offr...
train
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Most common route of transmission of hepatitis C:
[ "IV drug abuse", "Sexual contact", "Factor 8 concentrate", "Feco-oral route" ]
A
Screening of donated blood for HCV antibody has decreased the risk of transfusion-associated HCV infection Persons who inject illegal drugs with non-sterile needles or who sno cocaine with shared straws are at highest risk for HCV infection. In developed countries, most new HCV infections are related to intravenous dru...
train
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Specificity of a test refers to its ability to detect-
[ "True positive", "True negatives", "False negatives", "False positive" ]
B
Ans. is 'b' i.e., True negative Sensitivity* It is the ability of a test to identify correctly all those who have the disease, i.e., true positive.Specificity* It is the ability of a test to identify correctly those who do not have the disease i.e., true negative
train
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L.D. bodies are seen in:
[ "Kalahazar", "Toxoplasmosis", "Malaria", "Sleeping sickness" ]
A
null
train
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Commonest source of extradural hemorrhage: UP 09
[ "Middle meningeal aery", "Basilar aery", "Charcot's aery", "Middle cerebral aery" ]
A
Ans. Middle meningeal aery
train
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Distal clearance in surgery for carcinoma rectum is?
[ "2 cm", "5 cm", "10 cm", "8 cm" ]
A
Ans. is 'a' i.e., 2 cm
train
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Vitreous floaters are seen in
[ "Conjunctivitis", "Keratitis", "Anterior Scleritis", "Posterior uveitis" ]
D
Choroiditis refers to inflammation of the choroid which in most cases also involves the adjacent retina resulting in chorioretinitis. clinical features: -Painless visual symptoms like photopsia -Vitreous Floaters : black spots in front of the eyes - represent the vitreous inflammation - opacities that cast shadows on t...
train
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Which is given to prevent relapse in multiple sclerosis?
[ "IFN-beta", "Cyclosporine", "Corticosteroids", "I FIN-gamma" ]
A
Ans: a (IFN-beta) Ref: Harrison, 16th ed, p. 2467; Davidson, 20th ed, p. 1216Multiple sclerosis is characertised by a triad of inflammation, demylination and gliosis; the course can be relapsing - remitting or progressive.MS is twice more common in females. MS risk correlates with high socioeconomic status. High antibo...
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HIV post-exposure prophylaxis should be initiated as soon as possible after the exposure within-
[ "1-2 hrs", "14 hrs", "18 hrs", "72 hrs" ]
A
Ans. is 'a' i.e., 1-2 hrs o Anti-retroviral drug for post-exposure prophylaxis should be initiated as soon as possible after the exposure within the first few hours and no later than 72 hours. o So, the best answer here is 1-2 hours (first few hours). The guidelines for post-exposure prophylaxis of HIV are For routine ...
train
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Which of the following best describes adenovirus?
[ "Nonenveloped, double-stranded DNA virus with fibers at its veices", "Nonenveloped, double-stranded, circular DNA virus", "Enveloped, single-stranded, negative-sense RNA virus", "Enveloped, double-stranded, linear DNA virus with glycoprotein spikes" ]
A
.
train
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Transitional cell carcinoma of bladder is associated with-
[ "Schistosomiasis", "Naphthylamine", "Smoking", "All" ]
D
Ans. is 'a' i.e., Schistosomiasis; 'b' i.e., Naphthylamine & 'c' i.e., SmokingRisk factors for transitional cell carcinoma (TCC) of bladder ?I. Smoking ---> Major etiological factor.Occupational exposure to chemicals Nephthylamine benzidine, aniline dyes, acrolein.Schistosoma haematobium (Bilharziasis) ---> It is a ris...
train
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Typhoid ulcer ruptures at
[ "1st week", "2nd week", "3rd week", "4th week" ]
C
C. i.e. (3rd week) (69- 5 B & L 25th) (995- S. Das 5th)* After the second week, signs of peritonitis usually denotes perforation, which is confirmed by the presence of free.gas seen on x-ray (69-.B & L 25th)* Perforation usually occurs during the third week it occurs through ulcerated peyer's patches in the terminal il...
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Increasing severity of mental retardation in male members over generations is a result of:
[ "Mitochondrial DNA mutation", "Frameshift mutation", "Y-linked disorder", "Trinucleotide repeat mutation" ]
D
Anticipation Increasing severity of disease in successive generations Trinucleotide repeats cause worsening of clinical features with each successive generation.
train
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What is deposited in Bronze diabetes
[ "Bronze", "Copper", "Iron", "Carbon" ]
C
Answer is option 3 iron overload can also damage pancreas leading to the development of diabetes as diagnosed in this case by the biochemical parameters . This type of diabetes is called "Bronze Diabetes" due to the greyish colour of skin developed from deposition of excess iron. emedicinemedscape.com
train
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Fogo selvagem is a type of:
[ "Pemphigus vulgaris", "Pemghigus vegetans", "Pemphigus foliaceus", "Bullous pemphigoid" ]
C
Endemic pemphigus foliaceus common in rural pas of South America, paicularly ceain states of Brazil is known as fogo selvagem (wild fire) caused by bite of black fly. Ref: Rook's textbook of dermatology, 8th edition, Pg 40.13
train
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Indications to use Collagen cross linking
[ "Herpes infection", "Fungal corneal ulcer", "Pachymetry less than 400 nm", "Severe dry eye" ]
B
Riboflavin is used in collagen cross linking for keratoconus COLLAGEN CROSS LINKING C3R: Principle: Using riboflavin, we build up collagen cross links and provide cornea the strength to maintain its curvature f/b use contact lenses for few days. UV-A radiation 370 nm is used for 45 minutes. Indication: Keratoconus Post...
train
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Cholesterol from the liver is transpoed to the peripheral tissue mainly by:
[ "HDL", "LDL", "VLDL", "Chylomicrons" ]
B
Low-density lipoprotein/ LDLIt is one of the five major groups of lipoproteins, which in order of size, largest to smallest, are chylomicrons, VLDL, IDL, LDL, and HDL, that enable transpo of multiple different fat molecules, as well as cholesterol, within the water around cells and within the water-based bloodstream.LD...
train
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Following are the indications for salpinography' expect-
[ "Infertility", "Pelvic infections", "Recurrent abortions", "Abnormal uterine bleeding" ]
B
Ans: B
train
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A herd immunity of over - % is considered necessary to prevent epidemic spread of diphtheria -
[ "50%", "55%", "60%", "70%" ]
D
A herd immunity of over 70% is considered necessary to prevent epidemic spread, but some believe that the critical level may be as high as 90%.
train
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26. Bernoullis theorem explains:
[ "nasal polyp", "Thyroglossal cyst", "Zenkers diveiculum", "Laryngomalacia" ]
A
Bernoulli's phenomenon: Pressure drop next to a constriction causes a suction effect pulling the sinus mucosa into the nose, usually associated with antrochoanal polyps. Nasal polyps follow the Bernoulli's theorem as, the increased speed of the air flowing through the nose decreases the pressure in the nasal cavity, wh...
train
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Most common presentation of nasopharyngeal carcinoma is?
[ "Neck mass", "Trotter's triad", "Ophtalmoplegia", "Glue ear" ]
A
Ans. is'a'i.e., Neck mass(Ref: Dhingra Sn/e p. 265)Neck mass is the most common presentation (60-90%) due to cervical lymphadenopathy.
train
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Commonest presentation of wilm's tumour is ?
[ "Hematuria", "Abdomial lump", "Hydronephrosis", "Pain in abdomen." ]
B
Ans is 'b' ie Abdominal lump "MC presentation is painless abdominal mass usually discovered by the mother while routinely bathing the baby."
train
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You are surgeon posted at CHC. A patient of head injury come to you with rapidly deteriorating sensorium and progressive dilation and fixation of pupil. Neurosurgeon and CT scan is not available. You decide to make a burr hole to emergently relieve the intracranial pressure. Which of the following sites will you choose
[ "In the temporal region contralateral to the side of pupilary dilatation", "In the midline if both pupils are equal or it is not known which side dilated first.", "In the left temporal region if no localising sign is found", "Refer to higher centre if both pupils are equal or it is not known which side delate...
C
Burr Hole to emergently relieve the intracranial pressure should be done in the left temporal region if no localising sign is found, to evaluate and decompress the dominant hemisphere Choice of side for initial Burr Hole Sta with a temporal Burr hole on the side Ipsilateral to a blown pupil: This will be on the correct...
train
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