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Normalized Image Embeddings and Biomarker Layer

This folder contains normalized imaging features and biomarker intensity summaries for Z-Screen compound-level morphology analyses.

Files

  • normalized_image_embeddings.parquet
  • biomarker_intensity_layer.parquet

Contents

normalized_image_embeddings.parquet contains public compound identifiers and normalized morphology features, including principal-component-style image features. In the current release audit, it contains 21,795 rows and 39 columns.

biomarker_intensity_layer.parquet contains public compound identifiers and intensity measurements for protein/cellular-state markers. In the current release audit, it contains 18,942 rows and 11 columns, including BRD4, p21/CDKN1A, DAPI, actin, ConA, and p62/SQSTM1 intensity features.

How To Use

These files support compound-level image analysis, marker-state triage, and comparison between imaging and transcriptomic features. They are especially useful for p21, p62, and BRD4 protein-state analyses.