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Erratic winds challenge firefighters battling two major California blazes
MOJAVE NATIONAL PRESERVE, Calif. (AP) — A massive wildfire burning out of control in California’s Mojave National Preserve was spreading rapidly amid erratic winds, while firefighters reported progress against another major blaze to the southwest that prompted evacuations.
The York Fire that erupted Friday near the remote Caruthers Canyon area of the vast wildland preserve crossed the state line into Nevada on Sunday and sent smoke further east into the Las Vegas Valley.
Wind-driven flames 20 feet (6 meters) high in some spots charred more than 110 square miles (284 square kilometers) of desert scrub, juniper and Joshua tree woodland, according to an incident update. There was zero containment.
“The dry fuel acts as a ready ignition source, and when paired with those weather conditions it resulted in long-distance fire run and high flames, leading to extreme fire behavior,” the update said. No structures were threatened.
To the southwest, the Bonny Fire was holding steady at about 3.4 square miles (8.8 square kilometers) in rugged hills of Riverside County. More than 1,300 people were ordered to evacuate their homes Saturday near the community of Aguanga that is home to horse ranches and wineries.
Gusty winds and the chance of thunderstorms into Monday will heighten the risk of renewed growth, the California Department of Forestry and Fire Protection said in a statement.
One firefighter was injured in the blaze, which was 5% contained.
Copyright 2023 The Associated Press. All rights reserved. | https://www.kait8.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ | 2023-07-31T04:52:56 | 0 | https://www.kait8.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ |
What it costs to send your child to school
Education in Arkansas
JONESBORO, Ark. (KAIT) - While public school tuition is free to parents, it still comes with a steep price tag at the start of each school year.
Back-to-school expenses are a hurdle every family has to overcome towards the end of summer.
“We hear every year more and more people come to us, and they say, I didn’t know how I was going to provide school supplies for all of my children, Arkids Jonesboro Center Director Madison Rowe said.
According to data from the National Retail Federation, families with kids in K-12 expect to spend an average of $890 for back-to-school expenses this school year, about $25 more than last year.
Rowe works for Arkids Jonesboro, a pediatric daycare center that hosts school supply drives annually. She said paying for standard back-to-school supplies for one student can cost around $100.
“You’ve got tissues, you’ve got Clorox wipes, you’ve got your pencils, your markers, or crayons, pencil boxes, the backpack itself,” she explained. “You’ve got to be able to provide, you know, chargers. If they need a laptop, you also have to have access to the internet at home. So with all of that, the price can rise very quickly.”
In the 2021 to 2022 school year, Arkansas public schools shelled out more than $12,000 per student.
That’s $2,396 more than in the 2016 to 2017 school year and $971 more than in the 2020 to 2021 school year.
Alison Johnson works in education reform at the University of Arkansas. She said the expenditures per student goes directly into classroom instruction-- which means things like teacher salaries and curriculum. However, she added the Natural State doesn’t fair well when it comes to education spending.
“Part of it is we just have not poured as much money into education in this state as in other states, and I think that’s going to be reflected to some degree in our test scores.”
The district’s wealth largely determines how much a school district makes and spends.
“If you’re a poor district with a lot of kids, then you’re going to be needing a lot of aid from the state,” Johnson explains.
Even in districts like Batesville, where last school year’s total expenditures for the 2021-2022 school year were around $40 million, there’s an issue with adding room for additional instruction to accommodate its growth.
Batesville School District Superintendent Michael Hester blames inflation for the financial issues.
“We’ve got the inflationary cost of what things are costing us, which is far surpassing the money that we’re getting or made available to us to survive and operate on,” Hester said.
“Our district insurance, just for a property, went from $80,000 to like, $140,000 this year. That’s $60,000 more just for insurance in one year’s jump,” Hester continued.
According to Stephen Cornman with the U.S. Department of Education, some good news for Arkansas is a 10-year analysis showed a 6% increase in money spent per pupil from the 2020-2021 school year compared to the previous year, when the national growth was only 3.5%.
“It’s actually all the money that actually gets down into the classroom to help students. So the current expenditures per pupil is very, very important,” Cornman stated.
K8 News also spoke with Johnson about what the LEARNS Act could do to expenditures per pupil, and she said right now it’s unclear. Time will tell how it will affect district finances across the state.
Copyright 2023 KAIT. All rights reserved. | https://www.kait8.com/2023/07/31/what-it-costs-send-your-child-school/ | 2023-07-31T04:53:03 | 1 | https://www.kait8.com/2023/07/31/what-it-costs-send-your-child-school/ |
Erratic winds challenge firefighters battling two major California blazes
MOJAVE NATIONAL PRESERVE, Calif. (AP) — A massive wildfire burning out of control in California’s Mojave National Preserve was spreading rapidly amid erratic winds, while firefighters reported progress against another major blaze to the southwest that prompted evacuations.
The York Fire that erupted Friday near the remote Caruthers Canyon area of the vast wildland preserve crossed the state line into Nevada on Sunday and sent smoke further east into the Las Vegas Valley.
Wind-driven flames 20 feet (6 meters) high in some spots charred more than 110 square miles (284 square kilometers) of desert scrub, juniper and Joshua tree woodland, according to an incident update. There was zero containment.
“The dry fuel acts as a ready ignition source, and when paired with those weather conditions it resulted in long-distance fire run and high flames, leading to extreme fire behavior,” the update said. No structures were threatened.
To the southwest, the Bonny Fire was holding steady at about 3.4 square miles (8.8 square kilometers) in rugged hills of Riverside County. More than 1,300 people were ordered to evacuate their homes Saturday near the community of Aguanga that is home to horse ranches and wineries.
Gusty winds and the chance of thunderstorms into Monday will heighten the risk of renewed growth, the California Department of Forestry and Fire Protection said in a statement.
One firefighter was injured in the blaze, which was 5% contained.
Copyright 2023 The Associated Press. All rights reserved. | https://www.wbay.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ | 2023-07-31T04:53:03 | 1 | https://www.wbay.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ |
HONG KONG, July 31, 2023 /PRNewswire/ -- Akeso Inc. ("Akeso", the "Company"; 9926.HK), a commercial-stage biopharmaceutical company focused on developing and commercializing first-in-class and best-in-class innovative medicines globally, today announced that it is expected that the Company will record a profit of not less than RMB2.3 billion for the six months ended June 30, 2023. This is the first time for the Company to achieve half-year profits.
The turnaround from loss to profit during the Reporting Period was mainly attributable to:
- In respect of Ivonescimab (AK112, PD-1/VEGF) independently developed by the Company, the Company has entered into the collaborative and licensing agreement with Summit Therapeutics (details of which are set out in the announcement of the Company dated December 6, 2022). The Company has received the total upfront payment equivalent to US$500 million in full during the first quarter of 2023 (details of which are set out in the announcements of the Company dated January 26, 2023 and March 6, 2023). Part of such upfront payment was recognized as licensing fee income which significantly contributed to the revenue of the Company for the Reporting Period, and amounted to approximately RMB2.9 billion. The revenue recognition of the remaining portion of the upfront payment will be recognized as revenue in batches going forward.
- In respect of the Company's innovative product 开坦尼® (cadonilimab, PD-1/CTLA-4), since its launch in June 2022, it has recorded significant increase of the patients as well as product sales, which reflects the excellent clinical value of cadonilimab. In addition, 安尼可®(penpulimab, PD-1) also continued to contribute to the growth in the Company's product sales revenue during the Reporting Period.
- The Company has continued to optimise its cost management capabilities in a scientific and efficient way and has achieved better results in cost control while accelerating innovative products development and pipelines advancement.
About Akeso
Akeso (HKEX: 09926) is a commercial-stage biopharmaceutical company committed to the discovery, development, manufacturing, and commercialization of innovative medicines with high unmet medical needs worldwide. Founded in 2012, the Company has established a comprehensive in-house drug development platform (ACE Platform) and know-how, including R&D, clinical development, CMC (Chemistry, Manufacturing, and Controls), and commercialization capabilities.
With fully integrated multi-functional platform, Akeso is internally working on a robust pipeline of over 30 innovative assets in the fields of cancer, autoimmune disease, inflammation, metabolic disease, and other major therapeutic areas. 19 assets have entered clinical stage. Leveraging in-house developed bispecific platform technology ("Tetrabody technology"), the Company has advanced four potential first-in-class bispecific antibody drugs into market or clinical development, including cadonilimab (PD-1/CTLA-4), ivonescimab (PD-1/VEGF), PD-1/LAG-3, TIGIT/TGF-Beta bispecific antibodies. In June 2022, cadonilimab was approved by the NMPA and became the first commercialized PD-1 based bispecific drug globally. Another Akeso internally discovered and developed oncology product, penpulimab (a PD-1 antibody), was granted marketing approval in China in August 2021. In December 2022, the Company out-licensed breakthrough bispecific antibody, ivonescimab (PD-1/VEGF bi-specific antibody, AK112), with up to US$5 Billion total potential deal value to Summit Therapeutics for development and commercialization in the U.S., Canada, Europe, and Japan.
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SOURCE Akeso, Inc. | https://www.kait8.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ | 2023-07-31T04:53:09 | 0 | https://www.kait8.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ |
HONG KONG, July 31, 2023 /PRNewswire/ -- Akeso Inc. ("Akeso", the "Company"; 9926.HK), a commercial-stage biopharmaceutical company focused on developing and commercializing first-in-class and best-in-class innovative medicines globally, today announced that it is expected that the Company will record a profit of not less than RMB2.3 billion for the six months ended June 30, 2023. This is the first time for the Company to achieve half-year profits.
The turnaround from loss to profit during the Reporting Period was mainly attributable to:
- In respect of Ivonescimab (AK112, PD-1/VEGF) independently developed by the Company, the Company has entered into the collaborative and licensing agreement with Summit Therapeutics (details of which are set out in the announcement of the Company dated December 6, 2022). The Company has received the total upfront payment equivalent to US$500 million in full during the first quarter of 2023 (details of which are set out in the announcements of the Company dated January 26, 2023 and March 6, 2023). Part of such upfront payment was recognized as licensing fee income which significantly contributed to the revenue of the Company for the Reporting Period, and amounted to approximately RMB2.9 billion. The revenue recognition of the remaining portion of the upfront payment will be recognized as revenue in batches going forward.
- In respect of the Company's innovative product 开坦尼® (cadonilimab, PD-1/CTLA-4), since its launch in June 2022, it has recorded significant increase of the patients as well as product sales, which reflects the excellent clinical value of cadonilimab. In addition, 安尼可®(penpulimab, PD-1) also continued to contribute to the growth in the Company's product sales revenue during the Reporting Period.
- The Company has continued to optimise its cost management capabilities in a scientific and efficient way and has achieved better results in cost control while accelerating innovative products development and pipelines advancement.
About Akeso
Akeso (HKEX: 09926) is a commercial-stage biopharmaceutical company committed to the discovery, development, manufacturing, and commercialization of innovative medicines with high unmet medical needs worldwide. Founded in 2012, the Company has established a comprehensive in-house drug development platform (ACE Platform) and know-how, including R&D, clinical development, CMC (Chemistry, Manufacturing, and Controls), and commercialization capabilities.
With fully integrated multi-functional platform, Akeso is internally working on a robust pipeline of over 30 innovative assets in the fields of cancer, autoimmune disease, inflammation, metabolic disease, and other major therapeutic areas. 19 assets have entered clinical stage. Leveraging in-house developed bispecific platform technology ("Tetrabody technology"), the Company has advanced four potential first-in-class bispecific antibody drugs into market or clinical development, including cadonilimab (PD-1/CTLA-4), ivonescimab (PD-1/VEGF), PD-1/LAG-3, TIGIT/TGF-Beta bispecific antibodies. In June 2022, cadonilimab was approved by the NMPA and became the first commercialized PD-1 based bispecific drug globally. Another Akeso internally discovered and developed oncology product, penpulimab (a PD-1 antibody), was granted marketing approval in China in August 2021. In December 2022, the Company out-licensed breakthrough bispecific antibody, ivonescimab (PD-1/VEGF bi-specific antibody, AK112), with up to US$5 Billion total potential deal value to Summit Therapeutics for development and commercialization in the U.S., Canada, Europe, and Japan.
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SOURCE Akeso, Inc. | https://www.wbay.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ | 2023-07-31T04:53:09 | 1 | https://www.wbay.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ |
SEATTLE, July 30, 2023 /PRNewswire/ -- Monport Laser has been at the forefront of laser engraving innovation, spearheading the development of cutting-edge laser engravers and cutters. Building upon its world-leading expertise in the laser engraving industry, the company is now ready to captivate the market with its latest breakthroughs. In August, Monport Laser is scheduled to announce a range of new laser engraving machines, specifically engineered to handle various materials.
After six months of relentless effort from Monport's development technical team, their eagerly anticipated product will finally be revealed to all laser creators in early August of this year. The development of this innovative machine began with thousands of customer survey questionnaires for laser marking machines, rigorous testing, and product designer assessments. Engineers conducted over a dozen rounds of machine sample screening and in the final design stage, they took the unusual step of bringing in external senior personnel and engraving novices to carry out engraving tests for an entire month. This dedication to improvement and openness to feedback ensures a professional and user-friendly final fiber laser.
Monport GP Fiber Laser Series is not only Lightweight but Compact
Laser engraving machines have long faced difficulties when it comes to laser focusing, causing technical support headaches. Monport's latest innovation in marking machine can answer all these troubles. The new product boasts an electric and manual double lifting focus method, designed to make laser focusing seamless and improve the final engraving result. With this cutting-edge technology, users can operate without any barriers, and achieve the perfect, professional engraving effect.The electric lifting focus is suitable for beginners while the manual focus is the best for experienced users. This new integrated fiber laser is truly versatile in achieving any special engraving effects needed.
Breaking away from the conventional split type designs flooding the market, Monport introduces a game-changing one-piece design for their latest marking machine. This ingenious development not only saves valuable space but also ensures portability becomes a breeze. Bella, a senior developer at Monport Laser, proudly declared, "Our exceptional team of female developers has personally experienced the convenience of this machine. They effortlessly moved it from one studio to another, adjusting the base's height for easy handling right off the table. The commitment to a user-friendly experience is not just a mere claim."
In striking comparison to other conventional 33kg machines, Monport GP Series Fiber Series introduces their groundbreaking 20-22 kg all-in-one machine, setting a new industry standard for its exceptional lightness. The machine boasts rounded leading corners, diligently crafted to prevent unwanted bumps and damage during handling and transportation. Monport's thoughtful consideration extends further with the addition of a dustproof board, ensuring optimal performance and longevity. Endowed with an exceptional user-friendly experience and multifunctional capabilities, this machine embodies Monport Laser's unwavering dedication to continuous upgrades, always keeping the user at the forefront.
Monport GI Series MOPA Lasers Redefine Color Fast Marking
Monport's exciting product launch not only includes the highly anticipated new additions to the GP Series but also showcases the cutting-edge GI Series color engraving fiber machine. This JPT MOPA fiber laser is built to last, offering precision, durability, and longevity that surpasses expectations. With its remarkable laser cutting capability, it can effortlessly cut up to 0.05 mm with each pass, achieving an astonishing accuracy of ±0.1 microns.
Extensive Support and Remarkable Fiber Accessories
Complementing the multitude of advantages offered by their cutting-edge machine, Monport Laser goes above and beyond by providing customers with comprehensive support and unparalleled expandability. The new fiber series from Monport introduces a range of accessories designed to elevate the engraving experience. One notable addition is the safety shells, embedded with radiation protection and noise reduction functions, creating a secure and tranquil environment for users.
As a testament to their commitment to customer satisfaction, Monport Laser also includes 10 different test materials, ranging from metal rings to key chains and cards made from various metal materials, enabling users to explore and experiment with ease.
By empowering businesses and industries, expanding the creative landscape for maker spaces, unleashing innovation, and creating opportunities for growth, Monport Laser is at the forefront of revolutionizing the laser engraving field.
Company: Monport Laser
Contact email: official@monportlaser.com
Pre-sales Phone: (+1)332-251-1208
Monport Laser Website: https://monportlaser.com/
Monport Adress: Monport Tech Inc. 300 LENORA ST 878, SEATTLE, WA, 98121-2411, UNITED STATES
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SOURCE Monport Laser | https://www.kait8.com/prnewswire/2023/07/31/monport-laser-unveils-new-gp-series-gi-series-fiber-lasers-redefine-precision-performance/ | 2023-07-31T04:53:15 | 0 | https://www.kait8.com/prnewswire/2023/07/31/monport-laser-unveils-new-gp-series-gi-series-fiber-lasers-redefine-precision-performance/ |
CHENGDU, China, July 30, 2023 /PRNewswire/ -- On July 29, in the Men's Nanquan of Wushu tournament, China's athlete Cao Maoyuan won the first gold medal at the 31st FISU World University Games with a score of 9.770.
Cao Maoyuan stood on the podium, showcasing his glory to the world. The medal around his neck, accompanied by a radiant medal ribbon, caught everyone's attention. But what makes this seemingly ordinary medal ribbon so remarkable? It's the embodiment of Chengdu's cultural charm. According to Hu Guangjun, the director of the Chengdu Shu Brocade Research Institute, the medal ribbon for this edition of the Games has ingeniously incorporated the millennia-old weaving techniques of Shu brocade. Adorned with iconic symbols of Chengdu's historical and cultural significance, such as hibiscus flowers and sun birds, the ribbon exudes a captivating luster. This transforms China's intangible cultural heritage into a tangible "Rongguang" (the brilliance of Chengdu) that can be truly appreciated.
Shu brocade weaving skills are China's national intangible cultural heritage. Dating back to the Han Dynasty, Shu brocade has been a vital "protagonist" in trade along the Silk Road, earning its place as a cultural emblem of Chengdu and a symbol of cultural exchange between the East and West. With the unveiling of the first medal of the Games, Chengdu proudly showcases this cherished cultural business card to the world once again.
This outstanding cultural business card was produced in the workshop of Chengdu Shu Brocade Research Institute in Shuangliu District. According to Hu Guangjun, the location of the Chengdu Shu Brocade Research Institute in Shuangliu stems from its long history of silk culture. During the Three Kingdoms period, renowned strategist Zhuge Liang resided in Gemo Village, Shuangliu, where he emphasized the significance of Shu brocade by stating, "In the current circumstances of impoverishment and an empty treasury, we rely solely on Shu brocade for the necessary materials to confront our enemies." This highlights the historical importance of Shu brocade at that time. Moreover, a piece of Shu brocade known as "Lianzhu Loong Pattern Brocade" was excavated from the 226th tomb of Astana in Turpan, Xinjiang in the last century. The relic clearly records its origin in Shuangliu, bearing witness to the flourishing and prosperous Shu brocade industry in the Shuangliu region during the Tang Dynasty.
To infuse traditional Shu brocade with a fashionable touch, Hu Guangjun collaborated with a design team composed of Ma Liwa, a teacher, and students from the College of Chinese & ASEAN Arts at Chengdu University. Together, they tirelessly refined and revised the design, from pattern creation to machine production. This meticulous process took nearly six months to complete. Moreover, the transformation of mulberry silk into the medal ribbons required over 70 intricate steps.
Apart from the medal ribbons, the Chengdu Shu Brocade Research Institute has introduced a range of Games-related merchandise crafted from Shu brocade fabrics, including mirrors and bucket hats. These products seamlessly blend traditional culture with contemporary fashion elements, showcasing the progressive charm of Shu brocade. As a result, they have captured the attention of many young individuals who are now eager to explore and appreciate the beauty of Shu brocade.
Image Attachments Links:
Link: https://iop.asianetnews.net/view-attachment?attach-id=441679
Caption: Medal Ribbon of Chengdu FISU Games
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SOURCE The Chengdu Shu Brocade Research Institute | https://www.wbay.com/prnewswire/2023/07/31/chengdu-fisu-games-first-gold-medal-awarded-medal-ribbon-showcasing-chengdus-cultural-essence/ | 2023-07-31T04:53:16 | 0 | https://www.wbay.com/prnewswire/2023/07/31/chengdu-fisu-games-first-gold-medal-awarded-medal-ribbon-showcasing-chengdus-cultural-essence/ |
NANJING, China, July 31, 2023 /PRNewswire/ -- Nanjing Leads Biolabs Co., Ltd. (hereinafter referred to as "Leads Biolabs" or "Company") announced today that the National Medical Products Administration (NMPA) and the U.S. Food and Drug Administration (FDA) have approved its first-in-human Investigational New Drug (IND) applications for LBL-034, an anti-GPRC5D/CD3 bispecific antibody invented by Leads Biolabs with global intellectual property rights, for the treatment of relapsed/refractory multiple myeloma. Currently, no GPRC5D-targeting antibody has been approved for marketing.
This is a first-in-human, single-arm, multicenter, open-label, dose-escalation and expansion clinical study, and plans to enroll patients with relapsed/refractory multiple myeloma who have failed prior therapies including but not limited to at least one proteasome inhibitor (PI), one immunomodulator (IMiD) as well as other standard treatments. This study aims to evaluate the safety and tolerability of LBL-034, determine the recommended Phase II dose and assess its efficacy in patients with multiple myeloma.
"Despite recent progress and continuous advancements in multiple myeloma, the time between recurrences has been steadily decreasing, particularly as the number of treatment lines increases. This ultimately leads to emergence of relapsed or refractory multiple myeloma, reaffirming its status as an incurable malignant tumor that poses a serious threat to human life. In light of this challenging reality, the urgent need for more effective and innovative treatment options has never been more evident." said Dr. Charles Cai, Chief Medical Officer of Leads Biolabs, "LBL-034 adopts a unique molecular design, which enables the drug to specifically bind to GPRC5D-expressing tumor cells with high affinity, and reduces the risk of non-specific activation of T-cells, thereby enhancing anti-tumor efficacy and reducing potential risk of immunotoxicity. LBL-034 demonstrated robust anti-tumor activities and good safety profile in pre-clinical studies. We adhere to our tradition of innovation and aim to deliver an important, novel and effective treatment option for patients with poor prognosis of relapsed/refractory multiple myeloma."
About GPRC5D:
G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D) is a C-type 7-channel transmembrane receptor protein. GPRC5D is low expressed in normal human tissues but specifically overexpressed in multiple myeloma. The intensity of GPRC5D expression is an independent prognostic factor in multiple myeloma, and its overexpression is significantly associated with reduced overall survival. Therefore, GPRC5D may be an important potential target for the treatment of plasma cell diseases such as multiple myeloma.
About multiple myeloma:
Multiple myeloma is a malignant plasma cell disease caused by abnormal proliferation of clonal plasma cells, accounting for 10-15% of hematologic malignancies and about 1.4% of all malignancies. It is the second most common hematological malignancy in adults after non-Hodgkin's lymphoma and mostly occurs in the elderly. According to the data released by the World Health Organization (WHO), the number of new cases and deaths of multiple myeloma worldwide in 2020 were 176,000 and 117,000 respectively, and the number of new cases and deaths of multiple myeloma in China were 21,000 and 16,000 respectively. Currently, multiple myeloma is still an incurable malignant tumor, and the five-year survival rate of patients is approximately 24.8% in China, 33.3% in Japan, and 46.7% in the United States. In recent years, with the successful development of proteasome inhibitors (PIs), immunomodulatory drugs (IMiDs), selective nuclear output inhibitors, CD38-targeted antibodies, bispecific antibodies, and CAR-T cell therapies, the tumor response rate and survival prognosis have been significantly improved. However, multiple myeloma remains an unmet clinical need for more effective treatments.
About LBL-034:
LBL-034 is a humanized IgG1 subtype asymmetric bispecific antibody targeting both GPRC5D and CD3 and Leads Biolabs fully owns the worldwide intellectual property rights. LBL-034 induces T-cell-mediated killing of myeloma cells by redirecting CD3+ T-cells to myeloma cells expressing GPRC5D.
LBL-034 has the potential to be a transformative best-in-class GPRC5D-targeted immunotherapy for multiple myeloma. Clinical studies are planned to evaluate the safety and efficacy of LBL-034 in patients with relapsed/refractory multiple myeloma.
Nanjing Leads Biolabs Co., Ltd. is a clinical-stage biotechnology company founded in Nanjing by a team of senior U.S.-trained antibody drug developers. Since 2014, Leads Biolabs has been dedicated to the discovery and development of novel antibody drugs with independent intellectual property rights for the treatment of oncology and other major diseases of high unmet medical needs, particularly the challenges in cancer immunotherapy. Our extensive R&D pipeline consist of more than twenty novel tumor immunotherapy molecules based on monoclonal and bispecific antibody technology platforms. Leads Biolabs is committed to providing safe, effective, accessible and affordable new drugs to address the unmet needs of patients around the world.
For more information, please visit: https://www.leadsbiolabs.com
Business contact: bd@leadsbiolabs.com
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SOURCE LEADS BIOLABS | https://www.kait8.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ | 2023-07-31T04:53:22 | 0 | https://www.kait8.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ |
WICHITA, Kan. (KSNW) – Triple digit temperatures are creating financial challenges for people running their air conditioning units to keep cool, but the City of Wichita has resources available to help.
The city is extending free rides on air conditioned Q line buses to last through the week. The buses can help unhoused people travel from downtown to cooling centers in surrounding neighborhoods.
The three cooling centers offering water and air conditioning are located at the following addresses:
- Atwater, 2755 E. 19th St. N.
- Colvin, 2820 S. Roosevelt St.
- Evergreen, 2601 N. Arkansas St.
However, parents visiting Riverside Park Sunday were unaware of the cooling centers, and were facing some financial stress from footing their air conditioning bills.
“They’re stuck at home and they’re getting bored but then it’s hot outside,” said one mom at the park with her two boys.
Even inside, families faced challenges keeping cool.
“Our house doesn’t have a lot of insulation, so we get a lot of the heat in and a lot of the cold air escapes,” said Grace Barb, a mom visiting the park with her daughter.
Extra air conditioning use caused financial stress for the two moms.
“It does suck to get a bill that’s like… 50 to 100 dollars more,” said the mom visiting with her boys. “I mean, I’m not really excited to look at the bill this month.”
The city’s free Q line rides and cooling centers are meant to help prevent people from getting overheated.
“We’re just trying to keep people in air, keep them cool,” said Jeff Blubaugh, Wichita City Councilmember for District Four. “I mean, this is some record heat that we’re experiencing this week.”
Even with cooling centers open, it’s important to look out for neighbors and friends.
“Especially if you know somebody who’s having tough times or not running their air conditioning,” Blubaugh said. “Just check up on them.” | https://www.ksn.com/news/extreme-heat-causing-money-worries-for-wichitans/ | 2023-07-31T04:53:24 | 1 | https://www.ksn.com/news/extreme-heat-causing-money-worries-for-wichitans/ |
SEATTLE, July 30, 2023 /PRNewswire/ -- Monport Laser has been at the forefront of laser engraving innovation, spearheading the development of cutting-edge laser engravers and cutters. Building upon its world-leading expertise in the laser engraving industry, the company is now ready to captivate the market with its latest breakthroughs. In August, Monport Laser is scheduled to announce a range of new laser engraving machines, specifically engineered to handle various materials.
After six months of relentless effort from Monport's development technical team, their eagerly anticipated product will finally be revealed to all laser creators in early August of this year. The development of this innovative machine began with thousands of customer survey questionnaires for laser marking machines, rigorous testing, and product designer assessments. Engineers conducted over a dozen rounds of machine sample screening and in the final design stage, they took the unusual step of bringing in external senior personnel and engraving novices to carry out engraving tests for an entire month. This dedication to improvement and openness to feedback ensures a professional and user-friendly final fiber laser.
Monport GP Fiber Laser Series is not only Lightweight but Compact
Laser engraving machines have long faced difficulties when it comes to laser focusing, causing technical support headaches. Monport's latest innovation in marking machine can answer all these troubles. The new product boasts an electric and manual double lifting focus method, designed to make laser focusing seamless and improve the final engraving result. With this cutting-edge technology, users can operate without any barriers, and achieve the perfect, professional engraving effect.The electric lifting focus is suitable for beginners while the manual focus is the best for experienced users. This new integrated fiber laser is truly versatile in achieving any special engraving effects needed.
Breaking away from the conventional split type designs flooding the market, Monport introduces a game-changing one-piece design for their latest marking machine. This ingenious development not only saves valuable space but also ensures portability becomes a breeze. Bella, a senior developer at Monport Laser, proudly declared, "Our exceptional team of female developers has personally experienced the convenience of this machine. They effortlessly moved it from one studio to another, adjusting the base's height for easy handling right off the table. The commitment to a user-friendly experience is not just a mere claim."
In striking comparison to other conventional 33kg machines, Monport GP Series Fiber Series introduces their groundbreaking 20-22 kg all-in-one machine, setting a new industry standard for its exceptional lightness. The machine boasts rounded leading corners, diligently crafted to prevent unwanted bumps and damage during handling and transportation. Monport's thoughtful consideration extends further with the addition of a dustproof board, ensuring optimal performance and longevity. Endowed with an exceptional user-friendly experience and multifunctional capabilities, this machine embodies Monport Laser's unwavering dedication to continuous upgrades, always keeping the user at the forefront.
Monport GI Series MOPA Lasers Redefine Color Fast Marking
Monport's exciting product launch not only includes the highly anticipated new additions to the GP Series but also showcases the cutting-edge GI Series color engraving fiber machine. This JPT MOPA fiber laser is built to last, offering precision, durability, and longevity that surpasses expectations. With its remarkable laser cutting capability, it can effortlessly cut up to 0.05 mm with each pass, achieving an astonishing accuracy of ±0.1 microns.
Extensive Support and Remarkable Fiber Accessories
Complementing the multitude of advantages offered by their cutting-edge machine, Monport Laser goes above and beyond by providing customers with comprehensive support and unparalleled expandability. The new fiber series from Monport introduces a range of accessories designed to elevate the engraving experience. One notable addition is the safety shells, embedded with radiation protection and noise reduction functions, creating a secure and tranquil environment for users.
As a testament to their commitment to customer satisfaction, Monport Laser also includes 10 different test materials, ranging from metal rings to key chains and cards made from various metal materials, enabling users to explore and experiment with ease.
By empowering businesses and industries, expanding the creative landscape for maker spaces, unleashing innovation, and creating opportunities for growth, Monport Laser is at the forefront of revolutionizing the laser engraving field.
Company: Monport Laser
Contact email: official@monportlaser.com
Pre-sales Phone: (+1)332-251-1208
Monport Laser Website: https://monportlaser.com/
Monport Adress: Monport Tech Inc. 300 LENORA ST 878, SEATTLE, WA, 98121-2411, UNITED STATES
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SOURCE Monport Laser | https://www.wbay.com/prnewswire/2023/07/31/monport-laser-unveils-new-gp-series-gi-series-fiber-lasers-redefine-precision-performance/ | 2023-07-31T04:53:23 | 0 | https://www.wbay.com/prnewswire/2023/07/31/monport-laser-unveils-new-gp-series-gi-series-fiber-lasers-redefine-precision-performance/ |
Partnership adds cryptocurrency as a payment option for merchants using Optty's universal payment platform
SINGAPORE, July 30, 2023 /PRNewswire/ -- Optty, the world's first universal payments platform, today announced a new partnership with Triple-A, a licensed crypto payment gateway, to add cryptocurrency as a payment option on the platform. As the central hub connecting and streamlining a robust global network of Buy Now Pay Later (BNPL) providers, this milestone marks the launch of Optty's sixth payment architecture, further expanding viable payment options for merchants and convenience for their end customers.
Sign-up and integration with Optty is free. To get started, please visit: https://www.optty.com/merchant-account
"As the world's first true universal payments platform, Optty is agnostic and supportive of payments inclusion, a unique position that is designed to help retailers offer more choice than ever at checkout," said Natasha Zurnamer, CEO and founder of Optty. "With one simplified integration, not only can retailers access over 90 BNPLs and local payment methods in over 120 countries — they can now switch on crypto payments, a natural progression in our aim to simplify payments for retailers all over the world."
The first crypto payment gateway to be licensed by the Monetary Authority of Singapore, Triple-A is also licensed in Europe, through Banque de France's ACPR, and registered with the United States Financial Crimes Enforcement Network (FinCEN). Through the collaboration with Triple-A's white label crypto payment gateway, Optty enables retailers and merchants to offer a wide range of payment methods. This allows them to test and learn which payment types best resonate with their customers.
Tapping into diverse consumer payment preferences
With Optty's vast global network of gateways that license the company's unique payment stacks, merchants and retailers can now leverage Triple-A's gateway to accept cryptocurrencies such as Bitcoin (BTC), Ethereum (ETH), Tether (USDT), and USD Coin (USDC). Triple-A's crypto payment gateway is compatible with all crypto wallets, allowing customers to make hassle-free payments using their preferred wallet.
Through real-time crypto-to-fiat conversions facilitated by Triple-A, retailers can receive payments in cryptocurrencies without the need to manage them on their balance sheets and constantly monitor fluctuating exchange rates. Retailers enjoy next-day local currency bank settlements in 50+ currencies, enabling quick access to funds in their preferred currency. Additionally, businesses have the option to offer their customers the convenience of paying through Binance Pay.
Optty already offers Buy Now Pay Later, Debit and Credit, Digital Wallets, Peer to Peer payments, and bank transfer options, and the addition of crypto enables merchants to tap into the spending power of 420 million crypto owners worldwide. Optty plans to further expand payment architectures to a total of nine by the end of 2023.
"We are excited to partner with Optty and bring crypto payments to their merchants," said Eric Barbier, CEO of Triple-A. "This collaboration will help merchants take advantage of the growing demand for cryptocurrency payments, without the hassle of managing crypto assets on their balance sheets."
Disruption through simplification
Previously, retailers and merchants would need to spend a great deal of time and money on complex, one-by-one payment integration processes. Optty changed all this by eliminating it, revolutionizing the way merchants access payments methods globally. Available across ecommerce, IVR, and in-store, it is a true PaaS that offers retailers a simplified integration while providing a seamless and direct commercial partnership channel, enabling an application process with every payment provider in the solution.
About Optty
As a PaaS, Optty is the world's first true universal payments platform that integrates over 90 installment (BNPL) brands — more than any other existing single integration solution globally — and offers six payment architectures, soon to be nine by the end of 2023. Its payments-, partner- and channel-agnostic approach delivers wide payments connectivity globally to schemes, acquirers, gateways and retailers alike and offers a full white-label, customisable interface with hierarchy built in for network expansion ease.
For more information, please visit: https://www.optty.com/
About Triple-A
Triple-A is a licensed crypto payment gateway that helps businesses increase their revenue by enabling crypto payments and payouts, giving them access to the spending power of the fast-growing 420m+ cryptocurrency users.
Triple-A's white label crypto payments solutions allow businesses from all industries to leverage the benefits of the growing crypto market without being exposed to volatility risk or having to handle or convert digital currencies. Their solutions are compatible with all wallets, easy to integrate and offer instant confirmation, locked-in exchange rates and chargeback protection.
Licensed by the Monetary Authority of Singapore (MAS) and trusted by over 15,000 businesses, Triple-A makes accepting crypto payments simple for businesses across the globe.
For more information, please visit https://triple-a.io/.
View original content to download multimedia:
SOURCE Optty | https://www.kait8.com/prnewswire/2023/07/31/optty-partners-with-triple-a-expand-payment-architectures-into-cryptocurrencies/ | 2023-07-31T04:53:28 | 1 | https://www.kait8.com/prnewswire/2023/07/31/optty-partners-with-triple-a-expand-payment-architectures-into-cryptocurrencies/ |
NANJING, China, July 31, 2023 /PRNewswire/ -- Nanjing Leads Biolabs Co., Ltd. (hereinafter referred to as "Leads Biolabs" or "Company") announced today that the National Medical Products Administration (NMPA) and the U.S. Food and Drug Administration (FDA) have approved its first-in-human Investigational New Drug (IND) applications for LBL-034, an anti-GPRC5D/CD3 bispecific antibody invented by Leads Biolabs with global intellectual property rights, for the treatment of relapsed/refractory multiple myeloma. Currently, no GPRC5D-targeting antibody has been approved for marketing.
This is a first-in-human, single-arm, multicenter, open-label, dose-escalation and expansion clinical study, and plans to enroll patients with relapsed/refractory multiple myeloma who have failed prior therapies including but not limited to at least one proteasome inhibitor (PI), one immunomodulator (IMiD) as well as other standard treatments. This study aims to evaluate the safety and tolerability of LBL-034, determine the recommended Phase II dose and assess its efficacy in patients with multiple myeloma.
"Despite recent progress and continuous advancements in multiple myeloma, the time between recurrences has been steadily decreasing, particularly as the number of treatment lines increases. This ultimately leads to emergence of relapsed or refractory multiple myeloma, reaffirming its status as an incurable malignant tumor that poses a serious threat to human life. In light of this challenging reality, the urgent need for more effective and innovative treatment options has never been more evident." said Dr. Charles Cai, Chief Medical Officer of Leads Biolabs, "LBL-034 adopts a unique molecular design, which enables the drug to specifically bind to GPRC5D-expressing tumor cells with high affinity, and reduces the risk of non-specific activation of T-cells, thereby enhancing anti-tumor efficacy and reducing potential risk of immunotoxicity. LBL-034 demonstrated robust anti-tumor activities and good safety profile in pre-clinical studies. We adhere to our tradition of innovation and aim to deliver an important, novel and effective treatment option for patients with poor prognosis of relapsed/refractory multiple myeloma."
About GPRC5D:
G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D) is a C-type 7-channel transmembrane receptor protein. GPRC5D is low expressed in normal human tissues but specifically overexpressed in multiple myeloma. The intensity of GPRC5D expression is an independent prognostic factor in multiple myeloma, and its overexpression is significantly associated with reduced overall survival. Therefore, GPRC5D may be an important potential target for the treatment of plasma cell diseases such as multiple myeloma.
About multiple myeloma:
Multiple myeloma is a malignant plasma cell disease caused by abnormal proliferation of clonal plasma cells, accounting for 10-15% of hematologic malignancies and about 1.4% of all malignancies. It is the second most common hematological malignancy in adults after non-Hodgkin's lymphoma and mostly occurs in the elderly. According to the data released by the World Health Organization (WHO), the number of new cases and deaths of multiple myeloma worldwide in 2020 were 176,000 and 117,000 respectively, and the number of new cases and deaths of multiple myeloma in China were 21,000 and 16,000 respectively. Currently, multiple myeloma is still an incurable malignant tumor, and the five-year survival rate of patients is approximately 24.8% in China, 33.3% in Japan, and 46.7% in the United States. In recent years, with the successful development of proteasome inhibitors (PIs), immunomodulatory drugs (IMiDs), selective nuclear output inhibitors, CD38-targeted antibodies, bispecific antibodies, and CAR-T cell therapies, the tumor response rate and survival prognosis have been significantly improved. However, multiple myeloma remains an unmet clinical need for more effective treatments.
About LBL-034:
LBL-034 is a humanized IgG1 subtype asymmetric bispecific antibody targeting both GPRC5D and CD3 and Leads Biolabs fully owns the worldwide intellectual property rights. LBL-034 induces T-cell-mediated killing of myeloma cells by redirecting CD3+ T-cells to myeloma cells expressing GPRC5D.
LBL-034 has the potential to be a transformative best-in-class GPRC5D-targeted immunotherapy for multiple myeloma. Clinical studies are planned to evaluate the safety and efficacy of LBL-034 in patients with relapsed/refractory multiple myeloma.
Nanjing Leads Biolabs Co., Ltd. is a clinical-stage biotechnology company founded in Nanjing by a team of senior U.S.-trained antibody drug developers. Since 2014, Leads Biolabs has been dedicated to the discovery and development of novel antibody drugs with independent intellectual property rights for the treatment of oncology and other major diseases of high unmet medical needs, particularly the challenges in cancer immunotherapy. Our extensive R&D pipeline consist of more than twenty novel tumor immunotherapy molecules based on monoclonal and bispecific antibody technology platforms. Leads Biolabs is committed to providing safe, effective, accessible and affordable new drugs to address the unmet needs of patients around the world.
For more information, please visit: https://www.leadsbiolabs.com
Business contact: bd@leadsbiolabs.com
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SOURCE LEADS BIOLABS | https://www.wbay.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ | 2023-07-31T04:53:30 | 0 | https://www.wbay.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ |
More experienced principals leave the profession at higher rates
WASHINGTON, July 31, 2023 /PRNewswire/ -- Roughly 1 in 10 (11 percent) public school principals left the profession between the 2020-21 and 2021-22 school years, according to data from the National Teacher and Principal Survey (NTPS) released today by the National Center for Education Statistics (NCES), the statistical center within the U.S. Department of Education's Institute of Education Sciences (IES).
"Principal attrition is higher in public schools than it was 5 years ago, and veteran public school leaders with more years of experience leave the profession at higher rates than those with less experience," said NCES Commissioner Peggy G. Carr. "Principals are critical supports for a school's teachers and learners, and the country needs leaders in every school who are committed to the success of each student. These data are a valuable snapshot for those at the district and state levels who must address the issue of principal turnover in their schools."
Approximately 80 percent of 2020-21 public school principals remained at the same school one year later ("stayers"), which was lower than the percentage of 2016-17 public school principals who were still at their school 1 year later (82 percent). Six percent of 2020-21 public school principals moved to a different school ("movers"), and 11 percent left the principalship ("leavers"). For private school principals in 2020-21, approximately 83 percent remained at the same school during the following school year, 2 percent moved to a different school, and 10 percent left the principalship.
Additionally, among 2020-21 public school principals who somewhat or strongly agreed they would leave the principalship as soon as possible if they could get a higher paying job (about 25 percent), approximately 73 percent stayed the following school year, while about 15 percent left the profession.
"These data are critical to understanding patterns of principal attrition," said NCES Associate Commissioner Chris Chapman. "We are able to observe how principal attrition has changed over the years, as well as how principal attrition and mobility vary based on characteristics of the principals and their schools."
The report released today includes selected findings from the Principal Follow-up Survey (PFS), a longitudinal component of the National Teacher and Principal Survey (NTPS), which is a nationally representative survey of public and private K-12 schools, principals, and teachers in the 50 states and the District of Columbia. Data were collected from January 2022 through June 2022. The sample included about 6,500 public school principals and about 1,800 private school principals, for a total sample size of about 8,300 principals.
The data were collected as a follow-up to the 2020-21 NTPS to provide attrition and mobility information about principals in K-12 public and private schools. The purpose was to ascertain how many principals from the 2020-21 school year still worked as a principal in the same school 1 year later ("stayer"), how many had moved to become a principal in another school ("mover"), and how many were no longer working as a principal ("leaver").
Key Findings
- Of all public school principals in 2020-21, 11 percent left the profession by the 2021-22 school year. This was higher than in 2016-17, when 10 percent of all public school principals had left the profession since 2015-16, but not measurably different from the 2012-13 school year, when 12 percent of all public school principals had left the profession since the previous school year, or from 2008-09, when 12 percent of all public schools had left the profession since the previous school year.
- Of all public school principals in 2020-21 with more than 10 years of experience as a principal at any school, 15 percent left the profession by the 2021-22 school year. Of those principals with 10 years or more experience as a principal in their current school, 16 percent left the profession.
- A higher percentage of school principals 55 years of age or older left the profession compared to principals between 45-54 years of age.
- Among the 9 percent of 2020-21 public school principals with a salary of less than $75,000, 76 percent remained at the same school during the 2021–22 school year, 7 percent moved to a different school, and 13 percent left the principalship.
- Among the 33 percent of 2020-21 public school principals with a salary of $115,000 or more, 81 percent remained at the same school during the 2021-22 school year, 6 percent moved to a different school, and 10 percent left the principalship.
- Among the 62 percent of 2020-21 private school principals with a salary of less than $75,000, 81 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 10 percent left the principalship.
- Among the 13 percent of 2020-21 private school principals with a salary of $115,000 or more, 85 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 8 percent left the principalship.
The National Center for Education Statistics, a principal agency of the U.S. Federal Statistical System, is the statistical center of the U.S. Department of Education and the primary federal entity for collecting and analyzing data related to education in the U.S. and other nations. NCES fulfills a congressional mandate to collect, collate, analyze, and report complete statistics on the condition and progress of American education; conduct and publish reports; and review and report on education activities internationally.
Follow NCES on Twitter, Facebook, LinkedIn, and YouTube and subscribe to the NCES Newsflash to receive email notifications when new data is released.
The Institute of Education Sciences (IES) is the independent and nonpartisan statistics, research, and evaluation arm of the U.S. Department of Education. Its mission is to provide scientific evidence on which to ground education practice and policy and to share this information in formats that are useful and accessible to educators, parents, policymakers, researchers, and the public.
CONTACT: Josh Delarosa, National Center for Education Statistics, ARIS.NCES@ed.gov
James Elias, Hager Sharp, jelias@hagersharp.com
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SOURCE National Center for Education Statistics | https://www.kait8.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ | 2023-07-31T04:53:35 | 0 | https://www.kait8.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ |
Partnership adds cryptocurrency as a payment option for merchants using Optty's universal payment platform
SINGAPORE, July 30, 2023 /PRNewswire/ -- Optty, the world's first universal payments platform, today announced a new partnership with Triple-A, a licensed crypto payment gateway, to add cryptocurrency as a payment option on the platform. As the central hub connecting and streamlining a robust global network of Buy Now Pay Later (BNPL) providers, this milestone marks the launch of Optty's sixth payment architecture, further expanding viable payment options for merchants and convenience for their end customers.
Sign-up and integration with Optty is free. To get started, please visit: https://www.optty.com/merchant-account
"As the world's first true universal payments platform, Optty is agnostic and supportive of payments inclusion, a unique position that is designed to help retailers offer more choice than ever at checkout," said Natasha Zurnamer, CEO and founder of Optty. "With one simplified integration, not only can retailers access over 90 BNPLs and local payment methods in over 120 countries — they can now switch on crypto payments, a natural progression in our aim to simplify payments for retailers all over the world."
The first crypto payment gateway to be licensed by the Monetary Authority of Singapore, Triple-A is also licensed in Europe, through Banque de France's ACPR, and registered with the United States Financial Crimes Enforcement Network (FinCEN). Through the collaboration with Triple-A's white label crypto payment gateway, Optty enables retailers and merchants to offer a wide range of payment methods. This allows them to test and learn which payment types best resonate with their customers.
Tapping into diverse consumer payment preferences
With Optty's vast global network of gateways that license the company's unique payment stacks, merchants and retailers can now leverage Triple-A's gateway to accept cryptocurrencies such as Bitcoin (BTC), Ethereum (ETH), Tether (USDT), and USD Coin (USDC). Triple-A's crypto payment gateway is compatible with all crypto wallets, allowing customers to make hassle-free payments using their preferred wallet.
Through real-time crypto-to-fiat conversions facilitated by Triple-A, retailers can receive payments in cryptocurrencies without the need to manage them on their balance sheets and constantly monitor fluctuating exchange rates. Retailers enjoy next-day local currency bank settlements in 50+ currencies, enabling quick access to funds in their preferred currency. Additionally, businesses have the option to offer their customers the convenience of paying through Binance Pay.
Optty already offers Buy Now Pay Later, Debit and Credit, Digital Wallets, Peer to Peer payments, and bank transfer options, and the addition of crypto enables merchants to tap into the spending power of 420 million crypto owners worldwide. Optty plans to further expand payment architectures to a total of nine by the end of 2023.
"We are excited to partner with Optty and bring crypto payments to their merchants," said Eric Barbier, CEO of Triple-A. "This collaboration will help merchants take advantage of the growing demand for cryptocurrency payments, without the hassle of managing crypto assets on their balance sheets."
Disruption through simplification
Previously, retailers and merchants would need to spend a great deal of time and money on complex, one-by-one payment integration processes. Optty changed all this by eliminating it, revolutionizing the way merchants access payments methods globally. Available across ecommerce, IVR, and in-store, it is a true PaaS that offers retailers a simplified integration while providing a seamless and direct commercial partnership channel, enabling an application process with every payment provider in the solution.
About Optty
As a PaaS, Optty is the world's first true universal payments platform that integrates over 90 installment (BNPL) brands — more than any other existing single integration solution globally — and offers six payment architectures, soon to be nine by the end of 2023. Its payments-, partner- and channel-agnostic approach delivers wide payments connectivity globally to schemes, acquirers, gateways and retailers alike and offers a full white-label, customisable interface with hierarchy built in for network expansion ease.
For more information, please visit: https://www.optty.com/
About Triple-A
Triple-A is a licensed crypto payment gateway that helps businesses increase their revenue by enabling crypto payments and payouts, giving them access to the spending power of the fast-growing 420m+ cryptocurrency users.
Triple-A's white label crypto payments solutions allow businesses from all industries to leverage the benefits of the growing crypto market without being exposed to volatility risk or having to handle or convert digital currencies. Their solutions are compatible with all wallets, easy to integrate and offer instant confirmation, locked-in exchange rates and chargeback protection.
Licensed by the Monetary Authority of Singapore (MAS) and trusted by over 15,000 businesses, Triple-A makes accepting crypto payments simple for businesses across the globe.
For more information, please visit https://triple-a.io/.
View original content to download multimedia:
SOURCE Optty | https://www.wbay.com/prnewswire/2023/07/31/optty-partners-with-triple-a-expand-payment-architectures-into-cryptocurrencies/ | 2023-07-31T04:53:36 | 0 | https://www.wbay.com/prnewswire/2023/07/31/optty-partners-with-triple-a-expand-payment-architectures-into-cryptocurrencies/ |
HANOI, Vietnam, July 31, 2023 /PRNewswire/ -- SeABank's stock (SSB) has been officially selected by the Ho Chi Minh City Stock Exchange (HOSE) to be included in the VN30-Index basket - an index representing the top 30 stocks with the highest market capitalization and liquidity listed on the HOSE.
At the end of the trading session on July 28, 2023, the closing price of SSB's stock was 29,700 VND per share, bringing SeABank's market capitalization to over 72,875 billion VND, equivalent to nearly 3.07 billion USD.
According to the press release, on July 17, 2023, HOSE announced the portfolio of stocks included in the VN30 and VN-Finlead indexes, which would be effective from August 7, 2023. SSB was chosen to be included in the VN30 basket as it met the requirements set by the HOSE Index Rules. With an average market capitalization of nearly 65,000 billion Vietnamese dongs over the past six months, SSB is one of the largest capitalized stocks among those not included in the previous VN30 basket.
Throughout its operations, SeABank prioritizes transparency by providing information to shareholders, partners, and customers, complying with legal regulations, and following the directives of the Government and the State Bank of Vietnam to stabilize the market, ensure smooth operations, and promote business activities, thereby contributing to the country's socio-economic development.
SeABank's stock (SSB) was officially listed on the HOSE on March 24, 2021, with a reference price of 16,800 Vietnamese dongs per share on its first trading day. It has consistently experienced stable growth since then. In June 2023, SeABank successfully issued shares for dividend payment and additional capital from shareholder funds (bonus shares) with a total ratio of 20.3% to increase its charter capital to 24,537 billion Vietnamese dong.
Previously, SSB was also added to the Morgan Stanley Capital Index (MSCI) Frontier Markets Index starting from March 1, 2023. According to experts, stocks included in the MSCI Frontier Markets Index may be targeted by ETF (Exchange Traded Fund) funds that track frontier market stocks. Some funds use this index as a reference for investment or replicate its portfolio.
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SOURCE SeABank | https://www.kait8.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ | 2023-07-31T04:53:41 | 0 | https://www.kait8.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ |
More experienced principals leave the profession at higher rates
WASHINGTON, July 31, 2023 /PRNewswire/ -- Roughly 1 in 10 (11 percent) public school principals left the profession between the 2020-21 and 2021-22 school years, according to data from the National Teacher and Principal Survey (NTPS) released today by the National Center for Education Statistics (NCES), the statistical center within the U.S. Department of Education's Institute of Education Sciences (IES).
"Principal attrition is higher in public schools than it was 5 years ago, and veteran public school leaders with more years of experience leave the profession at higher rates than those with less experience," said NCES Commissioner Peggy G. Carr. "Principals are critical supports for a school's teachers and learners, and the country needs leaders in every school who are committed to the success of each student. These data are a valuable snapshot for those at the district and state levels who must address the issue of principal turnover in their schools."
Approximately 80 percent of 2020-21 public school principals remained at the same school one year later ("stayers"), which was lower than the percentage of 2016-17 public school principals who were still at their school 1 year later (82 percent). Six percent of 2020-21 public school principals moved to a different school ("movers"), and 11 percent left the principalship ("leavers"). For private school principals in 2020-21, approximately 83 percent remained at the same school during the following school year, 2 percent moved to a different school, and 10 percent left the principalship.
Additionally, among 2020-21 public school principals who somewhat or strongly agreed they would leave the principalship as soon as possible if they could get a higher paying job (about 25 percent), approximately 73 percent stayed the following school year, while about 15 percent left the profession.
"These data are critical to understanding patterns of principal attrition," said NCES Associate Commissioner Chris Chapman. "We are able to observe how principal attrition has changed over the years, as well as how principal attrition and mobility vary based on characteristics of the principals and their schools."
The report released today includes selected findings from the Principal Follow-up Survey (PFS), a longitudinal component of the National Teacher and Principal Survey (NTPS), which is a nationally representative survey of public and private K-12 schools, principals, and teachers in the 50 states and the District of Columbia. Data were collected from January 2022 through June 2022. The sample included about 6,500 public school principals and about 1,800 private school principals, for a total sample size of about 8,300 principals.
The data were collected as a follow-up to the 2020-21 NTPS to provide attrition and mobility information about principals in K-12 public and private schools. The purpose was to ascertain how many principals from the 2020-21 school year still worked as a principal in the same school 1 year later ("stayer"), how many had moved to become a principal in another school ("mover"), and how many were no longer working as a principal ("leaver").
Key Findings
- Of all public school principals in 2020-21, 11 percent left the profession by the 2021-22 school year. This was higher than in 2016-17, when 10 percent of all public school principals had left the profession since 2015-16, but not measurably different from the 2012-13 school year, when 12 percent of all public school principals had left the profession since the previous school year, or from 2008-09, when 12 percent of all public schools had left the profession since the previous school year.
- Of all public school principals in 2020-21 with more than 10 years of experience as a principal at any school, 15 percent left the profession by the 2021-22 school year. Of those principals with 10 years or more experience as a principal in their current school, 16 percent left the profession.
- A higher percentage of school principals 55 years of age or older left the profession compared to principals between 45-54 years of age.
- Among the 9 percent of 2020-21 public school principals with a salary of less than $75,000, 76 percent remained at the same school during the 2021–22 school year, 7 percent moved to a different school, and 13 percent left the principalship.
- Among the 33 percent of 2020-21 public school principals with a salary of $115,000 or more, 81 percent remained at the same school during the 2021-22 school year, 6 percent moved to a different school, and 10 percent left the principalship.
- Among the 62 percent of 2020-21 private school principals with a salary of less than $75,000, 81 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 10 percent left the principalship.
- Among the 13 percent of 2020-21 private school principals with a salary of $115,000 or more, 85 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 8 percent left the principalship.
The National Center for Education Statistics, a principal agency of the U.S. Federal Statistical System, is the statistical center of the U.S. Department of Education and the primary federal entity for collecting and analyzing data related to education in the U.S. and other nations. NCES fulfills a congressional mandate to collect, collate, analyze, and report complete statistics on the condition and progress of American education; conduct and publish reports; and review and report on education activities internationally.
Follow NCES on Twitter, Facebook, LinkedIn, and YouTube and subscribe to the NCES Newsflash to receive email notifications when new data is released.
The Institute of Education Sciences (IES) is the independent and nonpartisan statistics, research, and evaluation arm of the U.S. Department of Education. Its mission is to provide scientific evidence on which to ground education practice and policy and to share this information in formats that are useful and accessible to educators, parents, policymakers, researchers, and the public.
CONTACT: Josh Delarosa, National Center for Education Statistics, ARIS.NCES@ed.gov
James Elias, Hager Sharp, jelias@hagersharp.com
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SOURCE National Center for Education Statistics | https://www.wbay.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ | 2023-07-31T04:53:43 | 1 | https://www.wbay.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ |
CHENGDU, China, July 30, 2023 /PRNewswire/ -- On July 29, in the Men's Nanquan of Wushu tournament, China's athlete Cao Maoyuan won the first gold medal at the 31st FISU World University Games with a score of 9.770.
Cao Maoyuan stood on the podium, showcasing his glory to the world. The medal around his neck, accompanied by a radiant medal ribbon, caught everyone's attention. But what makes this seemingly ordinary medal ribbon so remarkable? It's the embodiment of Chengdu's cultural charm. According to Hu Guangjun, the director of the Chengdu Shu Brocade Research Institute, the medal ribbon for this edition of the Games has ingeniously incorporated the millennia-old weaving techniques of Shu brocade. Adorned with iconic symbols of Chengdu's historical and cultural significance, such as hibiscus flowers and sun birds, the ribbon exudes a captivating luster. This transforms China's intangible cultural heritage into a tangible "Rongguang" (the brilliance of Chengdu) that can be truly appreciated.
Shu brocade weaving skills are China's national intangible cultural heritage. Dating back to the Han Dynasty, Shu brocade has been a vital "protagonist" in trade along the Silk Road, earning its place as a cultural emblem of Chengdu and a symbol of cultural exchange between the East and West. With the unveiling of the first medal of the Games, Chengdu proudly showcases this cherished cultural business card to the world once again.
This outstanding cultural business card was produced in the workshop of Chengdu Shu Brocade Research Institute in Shuangliu District. According to Hu Guangjun, the location of the Chengdu Shu Brocade Research Institute in Shuangliu stems from its long history of silk culture. During the Three Kingdoms period, renowned strategist Zhuge Liang resided in Gemo Village, Shuangliu, where he emphasized the significance of Shu brocade by stating, "In the current circumstances of impoverishment and an empty treasury, we rely solely on Shu brocade for the necessary materials to confront our enemies." This highlights the historical importance of Shu brocade at that time. Moreover, a piece of Shu brocade known as "Lianzhu Loong Pattern Brocade" was excavated from the 226th tomb of Astana in Turpan, Xinjiang in the last century. The relic clearly records its origin in Shuangliu, bearing witness to the flourishing and prosperous Shu brocade industry in the Shuangliu region during the Tang Dynasty.
To infuse traditional Shu brocade with a fashionable touch, Hu Guangjun collaborated with a design team composed of Ma Liwa, a teacher, and students from the College of Chinese & ASEAN Arts at Chengdu University. Together, they tirelessly refined and revised the design, from pattern creation to machine production. This meticulous process took nearly six months to complete. Moreover, the transformation of mulberry silk into the medal ribbons required over 70 intricate steps.
Apart from the medal ribbons, the Chengdu Shu Brocade Research Institute has introduced a range of Games-related merchandise crafted from Shu brocade fabrics, including mirrors and bucket hats. These products seamlessly blend traditional culture with contemporary fashion elements, showcasing the progressive charm of Shu brocade. As a result, they have captured the attention of many young individuals who are now eager to explore and appreciate the beauty of Shu brocade.
Image Attachments Links:
Link: https://iop.asianetnews.net/view-attachment?attach-id=441679
Caption: Medal Ribbon of Chengdu FISU Games
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SOURCE The Chengdu Shu Brocade Research Institute | https://www.kait8.com/prnewswire/2023/07/31/chengdu-fisu-games-first-gold-medal-awarded-medal-ribbon-showcasing-chengdus-cultural-essence/ | 2023-07-31T04:53:47 | 1 | https://www.kait8.com/prnewswire/2023/07/31/chengdu-fisu-games-first-gold-medal-awarded-medal-ribbon-showcasing-chengdus-cultural-essence/ |
HANOI, Vietnam, July 31, 2023 /PRNewswire/ -- SeABank's stock (SSB) has been officially selected by the Ho Chi Minh City Stock Exchange (HOSE) to be included in the VN30-Index basket - an index representing the top 30 stocks with the highest market capitalization and liquidity listed on the HOSE.
At the end of the trading session on July 28, 2023, the closing price of SSB's stock was 29,700 VND per share, bringing SeABank's market capitalization to over 72,875 billion VND, equivalent to nearly 3.07 billion USD.
According to the press release, on July 17, 2023, HOSE announced the portfolio of stocks included in the VN30 and VN-Finlead indexes, which would be effective from August 7, 2023. SSB was chosen to be included in the VN30 basket as it met the requirements set by the HOSE Index Rules. With an average market capitalization of nearly 65,000 billion Vietnamese dongs over the past six months, SSB is one of the largest capitalized stocks among those not included in the previous VN30 basket.
Throughout its operations, SeABank prioritizes transparency by providing information to shareholders, partners, and customers, complying with legal regulations, and following the directives of the Government and the State Bank of Vietnam to stabilize the market, ensure smooth operations, and promote business activities, thereby contributing to the country's socio-economic development.
SeABank's stock (SSB) was officially listed on the HOSE on March 24, 2021, with a reference price of 16,800 Vietnamese dongs per share on its first trading day. It has consistently experienced stable growth since then. In June 2023, SeABank successfully issued shares for dividend payment and additional capital from shareholder funds (bonus shares) with a total ratio of 20.3% to increase its charter capital to 24,537 billion Vietnamese dong.
Previously, SSB was also added to the Morgan Stanley Capital Index (MSCI) Frontier Markets Index starting from March 1, 2023. According to experts, stocks included in the MSCI Frontier Markets Index may be targeted by ETF (Exchange Traded Fund) funds that track frontier market stocks. Some funds use this index as a reference for investment or replicate its portfolio.
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SOURCE SeABank | https://www.wbay.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ | 2023-07-31T04:53:49 | 0 | https://www.wbay.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ |
Posted: Jul 31, 2023 / 12:01 AM EDT Updated: Jul 28, 2023 / 02:24 PM EDT Close Modal Suggest a Correction Your name(required) Your email(required) Report a typo or grammatical error(required) Submit Δ Suggest a Correction
Everything you need to start crocheting at home If you want to start crocheting at home, put yarn, needles and several other supplies on your shopping list.
Every smart thermostat essential you need to learn A smart thermostat could be the answer to several problems. Read on to learn what makes them a brilliant addition to your home.
How to protect your home from harsh weather One of the biggest tasks you face as a homeowner is your never-ending battle with Mother Nature. | https://cbs4indy.com/contests/wttv-q3-home-improvement-sweepstakes/ | 2023-07-31T04:54:14 | 1 | https://cbs4indy.com/contests/wttv-q3-home-improvement-sweepstakes/ |
COLUMBUS, Ind. — A Tennessee man was seriously injured on I-65 southbound Sunday afternoon.
Indiana State Police confirmed 27-year-old Jonathan Brown of Lebanon, Tennessee, was struck by a motorcycle while he was trying to provide aid to a different motorcyclist that had been involved in a separate crash in southern Bartholomew County.
ISP’s investigation suggests Brown initially pulled onto the shoulder of I-65 southbound near mile marker 59 because his vehicle struck a bike that was lying in the left lane. Officials believe the bike possibly fell from a different vehicle traveling south.
After Brown pulled over, a group of motorcyclists approached the bicycle that was still in the roadway. One of the motorcyclists, 62-year-old Leslie D. Spillman of Lexington, Kentucky, struck the bike and crashed.
Brown saw Spillman crash and subsequently left his vehicle to provide assistance. As Brown left his vehicle, a 2004 Honda motorcycle that had passed Spillman before he crashed turned around and began traveling north on the southbound shoulder of the interstate. The motorcycle’s operator was 39-year-old Darrell Brooks of Lexington.
As he continued toward Spillman, Brown was struck by Brooks’ motorcycle. Brown sustained serious injures in the collision and was airlifted to a hospital in Louisville, Kentucky.
At the time of the Indiana State Police’s most recent update, Brown’s injuries were not considered to be life-threatening. Spillman also sustained non-life-threatening injuries, per ISP.
ISP is still investigating the crash. Alcohol and drugs are not believed to be factors in the collision. | https://cbs4indy.com/news/tennessee-man-seriously-injured-in-crash-on-i-65-sb-in-indiana/ | 2023-07-31T04:54:20 | 1 | https://cbs4indy.com/news/tennessee-man-seriously-injured-in-crash-on-i-65-sb-in-indiana/ |
Erratic winds challenge firefighters battling two major California blazes
MOJAVE NATIONAL PRESERVE, Calif. (AP) — A massive wildfire burning out of control in California’s Mojave National Preserve was spreading rapidly amid erratic winds, while firefighters reported progress against another major blaze to the southwest that prompted evacuations.
The York Fire that erupted Friday near the remote Caruthers Canyon area of the vast wildland preserve crossed the state line into Nevada on Sunday and sent smoke further east into the Las Vegas Valley.
Wind-driven flames 20 feet (6 meters) high in some spots charred more than 110 square miles (284 square kilometers) of desert scrub, juniper and Joshua tree woodland, according to an incident update. There was zero containment.
“The dry fuel acts as a ready ignition source, and when paired with those weather conditions it resulted in long-distance fire run and high flames, leading to extreme fire behavior,” the update said. No structures were threatened.
To the southwest, the Bonny Fire was holding steady at about 3.4 square miles (8.8 square kilometers) in rugged hills of Riverside County. More than 1,300 people were ordered to evacuate their homes Saturday near the community of Aguanga that is home to horse ranches and wineries.
Gusty winds and the chance of thunderstorms into Monday will heighten the risk of renewed growth, the California Department of Forestry and Fire Protection said in a statement.
One firefighter was injured in the blaze, which was 5% contained.
Copyright 2023 The Associated Press. All rights reserved. | https://www.kwch.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ | 2023-07-31T04:55:20 | 1 | https://www.kwch.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ |
HONG KONG, July 31, 2023 /PRNewswire/ -- Akeso Inc. ("Akeso", the "Company"; 9926.HK), a commercial-stage biopharmaceutical company focused on developing and commercializing first-in-class and best-in-class innovative medicines globally, today announced that it is expected that the Company will record a profit of not less than RMB2.3 billion for the six months ended June 30, 2023. This is the first time for the Company to achieve half-year profits.
The turnaround from loss to profit during the Reporting Period was mainly attributable to:
- In respect of Ivonescimab (AK112, PD-1/VEGF) independently developed by the Company, the Company has entered into the collaborative and licensing agreement with Summit Therapeutics (details of which are set out in the announcement of the Company dated December 6, 2022). The Company has received the total upfront payment equivalent to US$500 million in full during the first quarter of 2023 (details of which are set out in the announcements of the Company dated January 26, 2023 and March 6, 2023). Part of such upfront payment was recognized as licensing fee income which significantly contributed to the revenue of the Company for the Reporting Period, and amounted to approximately RMB2.9 billion. The revenue recognition of the remaining portion of the upfront payment will be recognized as revenue in batches going forward.
- In respect of the Company's innovative product 开坦尼® (cadonilimab, PD-1/CTLA-4), since its launch in June 2022, it has recorded significant increase of the patients as well as product sales, which reflects the excellent clinical value of cadonilimab. In addition, 安尼可®(penpulimab, PD-1) also continued to contribute to the growth in the Company's product sales revenue during the Reporting Period.
- The Company has continued to optimise its cost management capabilities in a scientific and efficient way and has achieved better results in cost control while accelerating innovative products development and pipelines advancement.
About Akeso
Akeso (HKEX: 09926) is a commercial-stage biopharmaceutical company committed to the discovery, development, manufacturing, and commercialization of innovative medicines with high unmet medical needs worldwide. Founded in 2012, the Company has established a comprehensive in-house drug development platform (ACE Platform) and know-how, including R&D, clinical development, CMC (Chemistry, Manufacturing, and Controls), and commercialization capabilities.
With fully integrated multi-functional platform, Akeso is internally working on a robust pipeline of over 30 innovative assets in the fields of cancer, autoimmune disease, inflammation, metabolic disease, and other major therapeutic areas. 19 assets have entered clinical stage. Leveraging in-house developed bispecific platform technology ("Tetrabody technology"), the Company has advanced four potential first-in-class bispecific antibody drugs into market or clinical development, including cadonilimab (PD-1/CTLA-4), ivonescimab (PD-1/VEGF), PD-1/LAG-3, TIGIT/TGF-Beta bispecific antibodies. In June 2022, cadonilimab was approved by the NMPA and became the first commercialized PD-1 based bispecific drug globally. Another Akeso internally discovered and developed oncology product, penpulimab (a PD-1 antibody), was granted marketing approval in China in August 2021. In December 2022, the Company out-licensed breakthrough bispecific antibody, ivonescimab (PD-1/VEGF bi-specific antibody, AK112), with up to US$5 Billion total potential deal value to Summit Therapeutics for development and commercialization in the U.S., Canada, Europe, and Japan.
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SOURCE Akeso, Inc. | https://www.kwch.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ | 2023-07-31T04:55:27 | 1 | https://www.kwch.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ |
CHENGDU, China, July 30, 2023 /PRNewswire/ -- On July 29, in the Men's Nanquan of Wushu tournament, China's athlete Cao Maoyuan won the first gold medal at the 31st FISU World University Games with a score of 9.770.
Cao Maoyuan stood on the podium, showcasing his glory to the world. The medal around his neck, accompanied by a radiant medal ribbon, caught everyone's attention. But what makes this seemingly ordinary medal ribbon so remarkable? It's the embodiment of Chengdu's cultural charm. According to Hu Guangjun, the director of the Chengdu Shu Brocade Research Institute, the medal ribbon for this edition of the Games has ingeniously incorporated the millennia-old weaving techniques of Shu brocade. Adorned with iconic symbols of Chengdu's historical and cultural significance, such as hibiscus flowers and sun birds, the ribbon exudes a captivating luster. This transforms China's intangible cultural heritage into a tangible "Rongguang" (the brilliance of Chengdu) that can be truly appreciated.
Shu brocade weaving skills are China's national intangible cultural heritage. Dating back to the Han Dynasty, Shu brocade has been a vital "protagonist" in trade along the Silk Road, earning its place as a cultural emblem of Chengdu and a symbol of cultural exchange between the East and West. With the unveiling of the first medal of the Games, Chengdu proudly showcases this cherished cultural business card to the world once again.
This outstanding cultural business card was produced in the workshop of Chengdu Shu Brocade Research Institute in Shuangliu District. According to Hu Guangjun, the location of the Chengdu Shu Brocade Research Institute in Shuangliu stems from its long history of silk culture. During the Three Kingdoms period, renowned strategist Zhuge Liang resided in Gemo Village, Shuangliu, where he emphasized the significance of Shu brocade by stating, "In the current circumstances of impoverishment and an empty treasury, we rely solely on Shu brocade for the necessary materials to confront our enemies." This highlights the historical importance of Shu brocade at that time. Moreover, a piece of Shu brocade known as "Lianzhu Loong Pattern Brocade" was excavated from the 226th tomb of Astana in Turpan, Xinjiang in the last century. The relic clearly records its origin in Shuangliu, bearing witness to the flourishing and prosperous Shu brocade industry in the Shuangliu region during the Tang Dynasty.
To infuse traditional Shu brocade with a fashionable touch, Hu Guangjun collaborated with a design team composed of Ma Liwa, a teacher, and students from the College of Chinese & ASEAN Arts at Chengdu University. Together, they tirelessly refined and revised the design, from pattern creation to machine production. This meticulous process took nearly six months to complete. Moreover, the transformation of mulberry silk into the medal ribbons required over 70 intricate steps.
Apart from the medal ribbons, the Chengdu Shu Brocade Research Institute has introduced a range of Games-related merchandise crafted from Shu brocade fabrics, including mirrors and bucket hats. These products seamlessly blend traditional culture with contemporary fashion elements, showcasing the progressive charm of Shu brocade. As a result, they have captured the attention of many young individuals who are now eager to explore and appreciate the beauty of Shu brocade.
Image Attachments Links:
Link: https://iop.asianetnews.net/view-attachment?attach-id=441679
Caption: Medal Ribbon of Chengdu FISU Games
View original content to download multimedia:
SOURCE The Chengdu Shu Brocade Research Institute | https://www.kwch.com/prnewswire/2023/07/31/chengdu-fisu-games-first-gold-medal-awarded-medal-ribbon-showcasing-chengdus-cultural-essence/ | 2023-07-31T04:55:33 | 1 | https://www.kwch.com/prnewswire/2023/07/31/chengdu-fisu-games-first-gold-medal-awarded-medal-ribbon-showcasing-chengdus-cultural-essence/ |
SEATTLE, July 30, 2023 /PRNewswire/ -- Monport Laser has been at the forefront of laser engraving innovation, spearheading the development of cutting-edge laser engravers and cutters. Building upon its world-leading expertise in the laser engraving industry, the company is now ready to captivate the market with its latest breakthroughs. In August, Monport Laser is scheduled to announce a range of new laser engraving machines, specifically engineered to handle various materials.
After six months of relentless effort from Monport's development technical team, their eagerly anticipated product will finally be revealed to all laser creators in early August of this year. The development of this innovative machine began with thousands of customer survey questionnaires for laser marking machines, rigorous testing, and product designer assessments. Engineers conducted over a dozen rounds of machine sample screening and in the final design stage, they took the unusual step of bringing in external senior personnel and engraving novices to carry out engraving tests for an entire month. This dedication to improvement and openness to feedback ensures a professional and user-friendly final fiber laser.
Monport GP Fiber Laser Series is not only Lightweight but Compact
Laser engraving machines have long faced difficulties when it comes to laser focusing, causing technical support headaches. Monport's latest innovation in marking machine can answer all these troubles. The new product boasts an electric and manual double lifting focus method, designed to make laser focusing seamless and improve the final engraving result. With this cutting-edge technology, users can operate without any barriers, and achieve the perfect, professional engraving effect.The electric lifting focus is suitable for beginners while the manual focus is the best for experienced users. This new integrated fiber laser is truly versatile in achieving any special engraving effects needed.
Breaking away from the conventional split type designs flooding the market, Monport introduces a game-changing one-piece design for their latest marking machine. This ingenious development not only saves valuable space but also ensures portability becomes a breeze. Bella, a senior developer at Monport Laser, proudly declared, "Our exceptional team of female developers has personally experienced the convenience of this machine. They effortlessly moved it from one studio to another, adjusting the base's height for easy handling right off the table. The commitment to a user-friendly experience is not just a mere claim."
In striking comparison to other conventional 33kg machines, Monport GP Series Fiber Series introduces their groundbreaking 20-22 kg all-in-one machine, setting a new industry standard for its exceptional lightness. The machine boasts rounded leading corners, diligently crafted to prevent unwanted bumps and damage during handling and transportation. Monport's thoughtful consideration extends further with the addition of a dustproof board, ensuring optimal performance and longevity. Endowed with an exceptional user-friendly experience and multifunctional capabilities, this machine embodies Monport Laser's unwavering dedication to continuous upgrades, always keeping the user at the forefront.
Monport GI Series MOPA Lasers Redefine Color Fast Marking
Monport's exciting product launch not only includes the highly anticipated new additions to the GP Series but also showcases the cutting-edge GI Series color engraving fiber machine. This JPT MOPA fiber laser is built to last, offering precision, durability, and longevity that surpasses expectations. With its remarkable laser cutting capability, it can effortlessly cut up to 0.05 mm with each pass, achieving an astonishing accuracy of ±0.1 microns.
Extensive Support and Remarkable Fiber Accessories
Complementing the multitude of advantages offered by their cutting-edge machine, Monport Laser goes above and beyond by providing customers with comprehensive support and unparalleled expandability. The new fiber series from Monport introduces a range of accessories designed to elevate the engraving experience. One notable addition is the safety shells, embedded with radiation protection and noise reduction functions, creating a secure and tranquil environment for users.
As a testament to their commitment to customer satisfaction, Monport Laser also includes 10 different test materials, ranging from metal rings to key chains and cards made from various metal materials, enabling users to explore and experiment with ease.
By empowering businesses and industries, expanding the creative landscape for maker spaces, unleashing innovation, and creating opportunities for growth, Monport Laser is at the forefront of revolutionizing the laser engraving field.
Company: Monport Laser
Contact email: official@monportlaser.com
Pre-sales Phone: (+1)332-251-1208
Monport Laser Website: https://monportlaser.com/
Monport Adress: Monport Tech Inc. 300 LENORA ST 878, SEATTLE, WA, 98121-2411, UNITED STATES
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SOURCE Monport Laser | https://www.kwch.com/prnewswire/2023/07/31/monport-laser-unveils-new-gp-series-gi-series-fiber-lasers-redefine-precision-performance/ | 2023-07-31T04:55:40 | 1 | https://www.kwch.com/prnewswire/2023/07/31/monport-laser-unveils-new-gp-series-gi-series-fiber-lasers-redefine-precision-performance/ |
NANJING, China, July 31, 2023 /PRNewswire/ -- Nanjing Leads Biolabs Co., Ltd. (hereinafter referred to as "Leads Biolabs" or "Company") announced today that the National Medical Products Administration (NMPA) and the U.S. Food and Drug Administration (FDA) have approved its first-in-human Investigational New Drug (IND) applications for LBL-034, an anti-GPRC5D/CD3 bispecific antibody invented by Leads Biolabs with global intellectual property rights, for the treatment of relapsed/refractory multiple myeloma. Currently, no GPRC5D-targeting antibody has been approved for marketing.
This is a first-in-human, single-arm, multicenter, open-label, dose-escalation and expansion clinical study, and plans to enroll patients with relapsed/refractory multiple myeloma who have failed prior therapies including but not limited to at least one proteasome inhibitor (PI), one immunomodulator (IMiD) as well as other standard treatments. This study aims to evaluate the safety and tolerability of LBL-034, determine the recommended Phase II dose and assess its efficacy in patients with multiple myeloma.
"Despite recent progress and continuous advancements in multiple myeloma, the time between recurrences has been steadily decreasing, particularly as the number of treatment lines increases. This ultimately leads to emergence of relapsed or refractory multiple myeloma, reaffirming its status as an incurable malignant tumor that poses a serious threat to human life. In light of this challenging reality, the urgent need for more effective and innovative treatment options has never been more evident." said Dr. Charles Cai, Chief Medical Officer of Leads Biolabs, "LBL-034 adopts a unique molecular design, which enables the drug to specifically bind to GPRC5D-expressing tumor cells with high affinity, and reduces the risk of non-specific activation of T-cells, thereby enhancing anti-tumor efficacy and reducing potential risk of immunotoxicity. LBL-034 demonstrated robust anti-tumor activities and good safety profile in pre-clinical studies. We adhere to our tradition of innovation and aim to deliver an important, novel and effective treatment option for patients with poor prognosis of relapsed/refractory multiple myeloma."
About GPRC5D:
G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D) is a C-type 7-channel transmembrane receptor protein. GPRC5D is low expressed in normal human tissues but specifically overexpressed in multiple myeloma. The intensity of GPRC5D expression is an independent prognostic factor in multiple myeloma, and its overexpression is significantly associated with reduced overall survival. Therefore, GPRC5D may be an important potential target for the treatment of plasma cell diseases such as multiple myeloma.
About multiple myeloma:
Multiple myeloma is a malignant plasma cell disease caused by abnormal proliferation of clonal plasma cells, accounting for 10-15% of hematologic malignancies and about 1.4% of all malignancies. It is the second most common hematological malignancy in adults after non-Hodgkin's lymphoma and mostly occurs in the elderly. According to the data released by the World Health Organization (WHO), the number of new cases and deaths of multiple myeloma worldwide in 2020 were 176,000 and 117,000 respectively, and the number of new cases and deaths of multiple myeloma in China were 21,000 and 16,000 respectively. Currently, multiple myeloma is still an incurable malignant tumor, and the five-year survival rate of patients is approximately 24.8% in China, 33.3% in Japan, and 46.7% in the United States. In recent years, with the successful development of proteasome inhibitors (PIs), immunomodulatory drugs (IMiDs), selective nuclear output inhibitors, CD38-targeted antibodies, bispecific antibodies, and CAR-T cell therapies, the tumor response rate and survival prognosis have been significantly improved. However, multiple myeloma remains an unmet clinical need for more effective treatments.
About LBL-034:
LBL-034 is a humanized IgG1 subtype asymmetric bispecific antibody targeting both GPRC5D and CD3 and Leads Biolabs fully owns the worldwide intellectual property rights. LBL-034 induces T-cell-mediated killing of myeloma cells by redirecting CD3+ T-cells to myeloma cells expressing GPRC5D.
LBL-034 has the potential to be a transformative best-in-class GPRC5D-targeted immunotherapy for multiple myeloma. Clinical studies are planned to evaluate the safety and efficacy of LBL-034 in patients with relapsed/refractory multiple myeloma.
Nanjing Leads Biolabs Co., Ltd. is a clinical-stage biotechnology company founded in Nanjing by a team of senior U.S.-trained antibody drug developers. Since 2014, Leads Biolabs has been dedicated to the discovery and development of novel antibody drugs with independent intellectual property rights for the treatment of oncology and other major diseases of high unmet medical needs, particularly the challenges in cancer immunotherapy. Our extensive R&D pipeline consist of more than twenty novel tumor immunotherapy molecules based on monoclonal and bispecific antibody technology platforms. Leads Biolabs is committed to providing safe, effective, accessible and affordable new drugs to address the unmet needs of patients around the world.
For more information, please visit: https://www.leadsbiolabs.com
Business contact: bd@leadsbiolabs.com
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SOURCE LEADS BIOLABS | https://www.kwch.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ | 2023-07-31T04:55:41 | 1 | https://www.kwch.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ |
Partnership adds cryptocurrency as a payment option for merchants using Optty's universal payment platform
SINGAPORE, July 30, 2023 /PRNewswire/ -- Optty, the world's first universal payments platform, today announced a new partnership with Triple-A, a licensed crypto payment gateway, to add cryptocurrency as a payment option on the platform. As the central hub connecting and streamlining a robust global network of Buy Now Pay Later (BNPL) providers, this milestone marks the launch of Optty's sixth payment architecture, further expanding viable payment options for merchants and convenience for their end customers.
Sign-up and integration with Optty is free. To get started, please visit: https://www.optty.com/merchant-account
"As the world's first true universal payments platform, Optty is agnostic and supportive of payments inclusion, a unique position that is designed to help retailers offer more choice than ever at checkout," said Natasha Zurnamer, CEO and founder of Optty. "With one simplified integration, not only can retailers access over 90 BNPLs and local payment methods in over 120 countries — they can now switch on crypto payments, a natural progression in our aim to simplify payments for retailers all over the world."
The first crypto payment gateway to be licensed by the Monetary Authority of Singapore, Triple-A is also licensed in Europe, through Banque de France's ACPR, and registered with the United States Financial Crimes Enforcement Network (FinCEN). Through the collaboration with Triple-A's white label crypto payment gateway, Optty enables retailers and merchants to offer a wide range of payment methods. This allows them to test and learn which payment types best resonate with their customers.
Tapping into diverse consumer payment preferences
With Optty's vast global network of gateways that license the company's unique payment stacks, merchants and retailers can now leverage Triple-A's gateway to accept cryptocurrencies such as Bitcoin (BTC), Ethereum (ETH), Tether (USDT), and USD Coin (USDC). Triple-A's crypto payment gateway is compatible with all crypto wallets, allowing customers to make hassle-free payments using their preferred wallet.
Through real-time crypto-to-fiat conversions facilitated by Triple-A, retailers can receive payments in cryptocurrencies without the need to manage them on their balance sheets and constantly monitor fluctuating exchange rates. Retailers enjoy next-day local currency bank settlements in 50+ currencies, enabling quick access to funds in their preferred currency. Additionally, businesses have the option to offer their customers the convenience of paying through Binance Pay.
Optty already offers Buy Now Pay Later, Debit and Credit, Digital Wallets, Peer to Peer payments, and bank transfer options, and the addition of crypto enables merchants to tap into the spending power of 420 million crypto owners worldwide. Optty plans to further expand payment architectures to a total of nine by the end of 2023.
"We are excited to partner with Optty and bring crypto payments to their merchants," said Eric Barbier, CEO of Triple-A. "This collaboration will help merchants take advantage of the growing demand for cryptocurrency payments, without the hassle of managing crypto assets on their balance sheets."
Disruption through simplification
Previously, retailers and merchants would need to spend a great deal of time and money on complex, one-by-one payment integration processes. Optty changed all this by eliminating it, revolutionizing the way merchants access payments methods globally. Available across ecommerce, IVR, and in-store, it is a true PaaS that offers retailers a simplified integration while providing a seamless and direct commercial partnership channel, enabling an application process with every payment provider in the solution.
About Optty
As a PaaS, Optty is the world's first true universal payments platform that integrates over 90 installment (BNPL) brands — more than any other existing single integration solution globally — and offers six payment architectures, soon to be nine by the end of 2023. Its payments-, partner- and channel-agnostic approach delivers wide payments connectivity globally to schemes, acquirers, gateways and retailers alike and offers a full white-label, customisable interface with hierarchy built in for network expansion ease.
For more information, please visit: https://www.optty.com/
About Triple-A
Triple-A is a licensed crypto payment gateway that helps businesses increase their revenue by enabling crypto payments and payouts, giving them access to the spending power of the fast-growing 420m+ cryptocurrency users.
Triple-A's white label crypto payments solutions allow businesses from all industries to leverage the benefits of the growing crypto market without being exposed to volatility risk or having to handle or convert digital currencies. Their solutions are compatible with all wallets, easy to integrate and offer instant confirmation, locked-in exchange rates and chargeback protection.
Licensed by the Monetary Authority of Singapore (MAS) and trusted by over 15,000 businesses, Triple-A makes accepting crypto payments simple for businesses across the globe.
For more information, please visit https://triple-a.io/.
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SOURCE Optty | https://www.kwch.com/prnewswire/2023/07/31/optty-partners-with-triple-a-expand-payment-architectures-into-cryptocurrencies/ | 2023-07-31T04:55:42 | 0 | https://www.kwch.com/prnewswire/2023/07/31/optty-partners-with-triple-a-expand-payment-architectures-into-cryptocurrencies/ |
Six migrant workers were struck Sunday afternoon by an SUV in a Walmart parking lot in North Carolina from what police are calling "an intentional assault with a vehicle."
"All six were transported to Atrium Health – Lincoln with various injuries. None of the injuries appear to be life threatening," the Lincolnton Police Department said in a Facebook post.
Police say they're still looking for the vehicle and driver involved in the incident, which they said took place at 1:17 pm ET. In the Facebook post, they describe the vehicle as an older model SUV with a luggage rack, and the driver as an older white male.
The motive for the attack is also still under investigation. Police told NPR via telephone late Sunday there is no further information.
Lincolnton is a small city of some 11,800 people located about an hour outside of Charlotte.
Copyright 2023 NPR. To see more, visit https://www.npr.org. | https://www.nepm.org/national-world-news/national-world-news/2023-07-30/an-suv-strikes-6-migrant-workers-in-walmart-parking-lot-in-north-carolina | 2023-07-31T04:55:57 | 1 | https://www.nepm.org/national-world-news/national-world-news/2023-07-30/an-suv-strikes-6-migrant-workers-in-walmart-parking-lot-in-north-carolina |
More experienced principals leave the profession at higher rates
WASHINGTON, July 31, 2023 /PRNewswire/ -- Roughly 1 in 10 (11 percent) public school principals left the profession between the 2020-21 and 2021-22 school years, according to data from the National Teacher and Principal Survey (NTPS) released today by the National Center for Education Statistics (NCES), the statistical center within the U.S. Department of Education's Institute of Education Sciences (IES).
"Principal attrition is higher in public schools than it was 5 years ago, and veteran public school leaders with more years of experience leave the profession at higher rates than those with less experience," said NCES Commissioner Peggy G. Carr. "Principals are critical supports for a school's teachers and learners, and the country needs leaders in every school who are committed to the success of each student. These data are a valuable snapshot for those at the district and state levels who must address the issue of principal turnover in their schools."
Approximately 80 percent of 2020-21 public school principals remained at the same school one year later ("stayers"), which was lower than the percentage of 2016-17 public school principals who were still at their school 1 year later (82 percent). Six percent of 2020-21 public school principals moved to a different school ("movers"), and 11 percent left the principalship ("leavers"). For private school principals in 2020-21, approximately 83 percent remained at the same school during the following school year, 2 percent moved to a different school, and 10 percent left the principalship.
Additionally, among 2020-21 public school principals who somewhat or strongly agreed they would leave the principalship as soon as possible if they could get a higher paying job (about 25 percent), approximately 73 percent stayed the following school year, while about 15 percent left the profession.
"These data are critical to understanding patterns of principal attrition," said NCES Associate Commissioner Chris Chapman. "We are able to observe how principal attrition has changed over the years, as well as how principal attrition and mobility vary based on characteristics of the principals and their schools."
The report released today includes selected findings from the Principal Follow-up Survey (PFS), a longitudinal component of the National Teacher and Principal Survey (NTPS), which is a nationally representative survey of public and private K-12 schools, principals, and teachers in the 50 states and the District of Columbia. Data were collected from January 2022 through June 2022. The sample included about 6,500 public school principals and about 1,800 private school principals, for a total sample size of about 8,300 principals.
The data were collected as a follow-up to the 2020-21 NTPS to provide attrition and mobility information about principals in K-12 public and private schools. The purpose was to ascertain how many principals from the 2020-21 school year still worked as a principal in the same school 1 year later ("stayer"), how many had moved to become a principal in another school ("mover"), and how many were no longer working as a principal ("leaver").
Key Findings
- Of all public school principals in 2020-21, 11 percent left the profession by the 2021-22 school year. This was higher than in 2016-17, when 10 percent of all public school principals had left the profession since 2015-16, but not measurably different from the 2012-13 school year, when 12 percent of all public school principals had left the profession since the previous school year, or from 2008-09, when 12 percent of all public schools had left the profession since the previous school year.
- Of all public school principals in 2020-21 with more than 10 years of experience as a principal at any school, 15 percent left the profession by the 2021-22 school year. Of those principals with 10 years or more experience as a principal in their current school, 16 percent left the profession.
- A higher percentage of school principals 55 years of age or older left the profession compared to principals between 45-54 years of age.
- Among the 9 percent of 2020-21 public school principals with a salary of less than $75,000, 76 percent remained at the same school during the 2021–22 school year, 7 percent moved to a different school, and 13 percent left the principalship.
- Among the 33 percent of 2020-21 public school principals with a salary of $115,000 or more, 81 percent remained at the same school during the 2021-22 school year, 6 percent moved to a different school, and 10 percent left the principalship.
- Among the 62 percent of 2020-21 private school principals with a salary of less than $75,000, 81 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 10 percent left the principalship.
- Among the 13 percent of 2020-21 private school principals with a salary of $115,000 or more, 85 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 8 percent left the principalship.
The National Center for Education Statistics, a principal agency of the U.S. Federal Statistical System, is the statistical center of the U.S. Department of Education and the primary federal entity for collecting and analyzing data related to education in the U.S. and other nations. NCES fulfills a congressional mandate to collect, collate, analyze, and report complete statistics on the condition and progress of American education; conduct and publish reports; and review and report on education activities internationally.
Follow NCES on Twitter, Facebook, LinkedIn, and YouTube and subscribe to the NCES Newsflash to receive email notifications when new data is released.
The Institute of Education Sciences (IES) is the independent and nonpartisan statistics, research, and evaluation arm of the U.S. Department of Education. Its mission is to provide scientific evidence on which to ground education practice and policy and to share this information in formats that are useful and accessible to educators, parents, policymakers, researchers, and the public.
CONTACT: Josh Delarosa, National Center for Education Statistics, ARIS.NCES@ed.gov
James Elias, Hager Sharp, jelias@hagersharp.com
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SOURCE National Center for Education Statistics | https://www.kwch.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ | 2023-07-31T04:56:02 | 1 | https://www.kwch.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ |
HANOI, Vietnam, July 31, 2023 /PRNewswire/ -- SeABank's stock (SSB) has been officially selected by the Ho Chi Minh City Stock Exchange (HOSE) to be included in the VN30-Index basket - an index representing the top 30 stocks with the highest market capitalization and liquidity listed on the HOSE.
At the end of the trading session on July 28, 2023, the closing price of SSB's stock was 29,700 VND per share, bringing SeABank's market capitalization to over 72,875 billion VND, equivalent to nearly 3.07 billion USD.
According to the press release, on July 17, 2023, HOSE announced the portfolio of stocks included in the VN30 and VN-Finlead indexes, which would be effective from August 7, 2023. SSB was chosen to be included in the VN30 basket as it met the requirements set by the HOSE Index Rules. With an average market capitalization of nearly 65,000 billion Vietnamese dongs over the past six months, SSB is one of the largest capitalized stocks among those not included in the previous VN30 basket.
Throughout its operations, SeABank prioritizes transparency by providing information to shareholders, partners, and customers, complying with legal regulations, and following the directives of the Government and the State Bank of Vietnam to stabilize the market, ensure smooth operations, and promote business activities, thereby contributing to the country's socio-economic development.
SeABank's stock (SSB) was officially listed on the HOSE on March 24, 2021, with a reference price of 16,800 Vietnamese dongs per share on its first trading day. It has consistently experienced stable growth since then. In June 2023, SeABank successfully issued shares for dividend payment and additional capital from shareholder funds (bonus shares) with a total ratio of 20.3% to increase its charter capital to 24,537 billion Vietnamese dong.
Previously, SSB was also added to the Morgan Stanley Capital Index (MSCI) Frontier Markets Index starting from March 1, 2023. According to experts, stocks included in the MSCI Frontier Markets Index may be targeted by ETF (Exchange Traded Fund) funds that track frontier market stocks. Some funds use this index as a reference for investment or replicate its portfolio.
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SOURCE SeABank | https://www.kwch.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ | 2023-07-31T04:56:08 | 0 | https://www.kwch.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ |
Six migrant workers were struck Sunday afternoon by an SUV in a Walmart parking lot in North Carolina from what police are calling "an intentional assault with a vehicle."
"All six were transported to Atrium Health – Lincoln with various injuries. None of the injuries appear to be life threatening," the Lincolnton Police Department said in a Facebook post.
Police say they're still looking for the vehicle and driver involved in the incident, which they said took place at 1:17 pm ET. In the Facebook post, they describe the vehicle as an older model SUV with a luggage rack, and the driver as an older white male.
The motive for the attack is also still under investigation. Police told NPR via telephone late Sunday there is no further information.
Lincolnton is a small city of some 11,800 people located about an hour outside of Charlotte.
Copyright 2023 NPR. To see more, visit https://www.npr.org. | https://www.wunc.org/2023-07-30/an-suv-strikes-6-migrant-workers-in-walmart-parking-lot-in-north-carolina | 2023-07-31T04:56:21 | 0 | https://www.wunc.org/2023-07-30/an-suv-strikes-6-migrant-workers-in-walmart-parking-lot-in-north-carolina |
Erratic winds challenge firefighters battling two major California blazes
MOJAVE NATIONAL PRESERVE, Calif. (AP) — A massive wildfire burning out of control in California’s Mojave National Preserve was spreading rapidly amid erratic winds, while firefighters reported progress against another major blaze to the southwest that prompted evacuations.
The York Fire that erupted Friday near the remote Caruthers Canyon area of the vast wildland preserve crossed the state line into Nevada on Sunday and sent smoke further east into the Las Vegas Valley.
Wind-driven flames 20 feet (6 meters) high in some spots charred more than 110 square miles (284 square kilometers) of desert scrub, juniper and Joshua tree woodland, according to an incident update. There was zero containment.
“The dry fuel acts as a ready ignition source, and when paired with those weather conditions it resulted in long-distance fire run and high flames, leading to extreme fire behavior,” the update said. No structures were threatened.
To the southwest, the Bonny Fire was holding steady at about 3.4 square miles (8.8 square kilometers) in rugged hills of Riverside County. More than 1,300 people were ordered to evacuate their homes Saturday near the community of Aguanga that is home to horse ranches and wineries.
Gusty winds and the chance of thunderstorms into Monday will heighten the risk of renewed growth, the California Department of Forestry and Fire Protection said in a statement.
One firefighter was injured in the blaze, which was 5% contained.
Copyright 2023 The Associated Press. All rights reserved. | https://www.wafb.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ | 2023-07-31T04:56:21 | 0 | https://www.wafb.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ |
HONG KONG, July 31, 2023 /PRNewswire/ -- Akeso Inc. ("Akeso", the "Company"; 9926.HK), a commercial-stage biopharmaceutical company focused on developing and commercializing first-in-class and best-in-class innovative medicines globally, today announced that it is expected that the Company will record a profit of not less than RMB2.3 billion for the six months ended June 30, 2023. This is the first time for the Company to achieve half-year profits.
The turnaround from loss to profit during the Reporting Period was mainly attributable to:
- In respect of Ivonescimab (AK112, PD-1/VEGF) independently developed by the Company, the Company has entered into the collaborative and licensing agreement with Summit Therapeutics (details of which are set out in the announcement of the Company dated December 6, 2022). The Company has received the total upfront payment equivalent to US$500 million in full during the first quarter of 2023 (details of which are set out in the announcements of the Company dated January 26, 2023 and March 6, 2023). Part of such upfront payment was recognized as licensing fee income which significantly contributed to the revenue of the Company for the Reporting Period, and amounted to approximately RMB2.9 billion. The revenue recognition of the remaining portion of the upfront payment will be recognized as revenue in batches going forward.
- In respect of the Company's innovative product 开坦尼® (cadonilimab, PD-1/CTLA-4), since its launch in June 2022, it has recorded significant increase of the patients as well as product sales, which reflects the excellent clinical value of cadonilimab. In addition, 安尼可®(penpulimab, PD-1) also continued to contribute to the growth in the Company's product sales revenue during the Reporting Period.
- The Company has continued to optimise its cost management capabilities in a scientific and efficient way and has achieved better results in cost control while accelerating innovative products development and pipelines advancement.
About Akeso
Akeso (HKEX: 09926) is a commercial-stage biopharmaceutical company committed to the discovery, development, manufacturing, and commercialization of innovative medicines with high unmet medical needs worldwide. Founded in 2012, the Company has established a comprehensive in-house drug development platform (ACE Platform) and know-how, including R&D, clinical development, CMC (Chemistry, Manufacturing, and Controls), and commercialization capabilities.
With fully integrated multi-functional platform, Akeso is internally working on a robust pipeline of over 30 innovative assets in the fields of cancer, autoimmune disease, inflammation, metabolic disease, and other major therapeutic areas. 19 assets have entered clinical stage. Leveraging in-house developed bispecific platform technology ("Tetrabody technology"), the Company has advanced four potential first-in-class bispecific antibody drugs into market or clinical development, including cadonilimab (PD-1/CTLA-4), ivonescimab (PD-1/VEGF), PD-1/LAG-3, TIGIT/TGF-Beta bispecific antibodies. In June 2022, cadonilimab was approved by the NMPA and became the first commercialized PD-1 based bispecific drug globally. Another Akeso internally discovered and developed oncology product, penpulimab (a PD-1 antibody), was granted marketing approval in China in August 2021. In December 2022, the Company out-licensed breakthrough bispecific antibody, ivonescimab (PD-1/VEGF bi-specific antibody, AK112), with up to US$5 Billion total potential deal value to Summit Therapeutics for development and commercialization in the U.S., Canada, Europe, and Japan.
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SOURCE Akeso, Inc. | https://www.wafb.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ | 2023-07-31T04:56:27 | 0 | https://www.wafb.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ |
Six migrant workers were struck Sunday afternoon by an SUV in a Walmart parking lot in North Carolina from what police are calling "an intentional assault with a vehicle."
"All six were transported to Atrium Health – Lincoln with various injuries. None of the injuries appear to be life threatening," the Lincolnton Police Department said in a Facebook post.
Police say they're still looking for the vehicle and driver involved in the incident, which they said took place at 1:17 pm ET. In the Facebook post, they describe the vehicle as an older model SUV with a luggage rack, and the driver as an older white male.
The motive for the attack is also still under investigation. Police told NPR via telephone late Sunday there is no further information.
Lincolnton is a small city of some 11,800 people located about an hour outside of Charlotte.
Copyright 2023 NPR. To see more, visit https://www.npr.org. | https://www.wbaa.org/2023-07-30/an-suv-strikes-6-migrant-workers-in-walmart-parking-lot-in-north-carolina | 2023-07-31T04:56:29 | 0 | https://www.wbaa.org/2023-07-30/an-suv-strikes-6-migrant-workers-in-walmart-parking-lot-in-north-carolina |
CHENGDU, China, July 30, 2023 /PRNewswire/ -- On July 29, in the Men's Nanquan of Wushu tournament, China's athlete Cao Maoyuan won the first gold medal at the 31st FISU World University Games with a score of 9.770.
Cao Maoyuan stood on the podium, showcasing his glory to the world. The medal around his neck, accompanied by a radiant medal ribbon, caught everyone's attention. But what makes this seemingly ordinary medal ribbon so remarkable? It's the embodiment of Chengdu's cultural charm. According to Hu Guangjun, the director of the Chengdu Shu Brocade Research Institute, the medal ribbon for this edition of the Games has ingeniously incorporated the millennia-old weaving techniques of Shu brocade. Adorned with iconic symbols of Chengdu's historical and cultural significance, such as hibiscus flowers and sun birds, the ribbon exudes a captivating luster. This transforms China's intangible cultural heritage into a tangible "Rongguang" (the brilliance of Chengdu) that can be truly appreciated.
Shu brocade weaving skills are China's national intangible cultural heritage. Dating back to the Han Dynasty, Shu brocade has been a vital "protagonist" in trade along the Silk Road, earning its place as a cultural emblem of Chengdu and a symbol of cultural exchange between the East and West. With the unveiling of the first medal of the Games, Chengdu proudly showcases this cherished cultural business card to the world once again.
This outstanding cultural business card was produced in the workshop of Chengdu Shu Brocade Research Institute in Shuangliu District. According to Hu Guangjun, the location of the Chengdu Shu Brocade Research Institute in Shuangliu stems from its long history of silk culture. During the Three Kingdoms period, renowned strategist Zhuge Liang resided in Gemo Village, Shuangliu, where he emphasized the significance of Shu brocade by stating, "In the current circumstances of impoverishment and an empty treasury, we rely solely on Shu brocade for the necessary materials to confront our enemies." This highlights the historical importance of Shu brocade at that time. Moreover, a piece of Shu brocade known as "Lianzhu Loong Pattern Brocade" was excavated from the 226th tomb of Astana in Turpan, Xinjiang in the last century. The relic clearly records its origin in Shuangliu, bearing witness to the flourishing and prosperous Shu brocade industry in the Shuangliu region during the Tang Dynasty.
To infuse traditional Shu brocade with a fashionable touch, Hu Guangjun collaborated with a design team composed of Ma Liwa, a teacher, and students from the College of Chinese & ASEAN Arts at Chengdu University. Together, they tirelessly refined and revised the design, from pattern creation to machine production. This meticulous process took nearly six months to complete. Moreover, the transformation of mulberry silk into the medal ribbons required over 70 intricate steps.
Apart from the medal ribbons, the Chengdu Shu Brocade Research Institute has introduced a range of Games-related merchandise crafted from Shu brocade fabrics, including mirrors and bucket hats. These products seamlessly blend traditional culture with contemporary fashion elements, showcasing the progressive charm of Shu brocade. As a result, they have captured the attention of many young individuals who are now eager to explore and appreciate the beauty of Shu brocade.
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Link: https://iop.asianetnews.net/view-attachment?attach-id=441679
Caption: Medal Ribbon of Chengdu FISU Games
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SOURCE The Chengdu Shu Brocade Research Institute | https://www.wafb.com/prnewswire/2023/07/31/chengdu-fisu-games-first-gold-medal-awarded-medal-ribbon-showcasing-chengdus-cultural-essence/ | 2023-07-31T04:56:33 | 1 | https://www.wafb.com/prnewswire/2023/07/31/chengdu-fisu-games-first-gold-medal-awarded-medal-ribbon-showcasing-chengdus-cultural-essence/ |
SEATTLE, July 30, 2023 /PRNewswire/ -- Monport Laser has been at the forefront of laser engraving innovation, spearheading the development of cutting-edge laser engravers and cutters. Building upon its world-leading expertise in the laser engraving industry, the company is now ready to captivate the market with its latest breakthroughs. In August, Monport Laser is scheduled to announce a range of new laser engraving machines, specifically engineered to handle various materials.
After six months of relentless effort from Monport's development technical team, their eagerly anticipated product will finally be revealed to all laser creators in early August of this year. The development of this innovative machine began with thousands of customer survey questionnaires for laser marking machines, rigorous testing, and product designer assessments. Engineers conducted over a dozen rounds of machine sample screening and in the final design stage, they took the unusual step of bringing in external senior personnel and engraving novices to carry out engraving tests for an entire month. This dedication to improvement and openness to feedback ensures a professional and user-friendly final fiber laser.
Monport GP Fiber Laser Series is not only Lightweight but Compact
Laser engraving machines have long faced difficulties when it comes to laser focusing, causing technical support headaches. Monport's latest innovation in marking machine can answer all these troubles. The new product boasts an electric and manual double lifting focus method, designed to make laser focusing seamless and improve the final engraving result. With this cutting-edge technology, users can operate without any barriers, and achieve the perfect, professional engraving effect.The electric lifting focus is suitable for beginners while the manual focus is the best for experienced users. This new integrated fiber laser is truly versatile in achieving any special engraving effects needed.
Breaking away from the conventional split type designs flooding the market, Monport introduces a game-changing one-piece design for their latest marking machine. This ingenious development not only saves valuable space but also ensures portability becomes a breeze. Bella, a senior developer at Monport Laser, proudly declared, "Our exceptional team of female developers has personally experienced the convenience of this machine. They effortlessly moved it from one studio to another, adjusting the base's height for easy handling right off the table. The commitment to a user-friendly experience is not just a mere claim."
In striking comparison to other conventional 33kg machines, Monport GP Series Fiber Series introduces their groundbreaking 20-22 kg all-in-one machine, setting a new industry standard for its exceptional lightness. The machine boasts rounded leading corners, diligently crafted to prevent unwanted bumps and damage during handling and transportation. Monport's thoughtful consideration extends further with the addition of a dustproof board, ensuring optimal performance and longevity. Endowed with an exceptional user-friendly experience and multifunctional capabilities, this machine embodies Monport Laser's unwavering dedication to continuous upgrades, always keeping the user at the forefront.
Monport GI Series MOPA Lasers Redefine Color Fast Marking
Monport's exciting product launch not only includes the highly anticipated new additions to the GP Series but also showcases the cutting-edge GI Series color engraving fiber machine. This JPT MOPA fiber laser is built to last, offering precision, durability, and longevity that surpasses expectations. With its remarkable laser cutting capability, it can effortlessly cut up to 0.05 mm with each pass, achieving an astonishing accuracy of ±0.1 microns.
Extensive Support and Remarkable Fiber Accessories
Complementing the multitude of advantages offered by their cutting-edge machine, Monport Laser goes above and beyond by providing customers with comprehensive support and unparalleled expandability. The new fiber series from Monport introduces a range of accessories designed to elevate the engraving experience. One notable addition is the safety shells, embedded with radiation protection and noise reduction functions, creating a secure and tranquil environment for users.
As a testament to their commitment to customer satisfaction, Monport Laser also includes 10 different test materials, ranging from metal rings to key chains and cards made from various metal materials, enabling users to explore and experiment with ease.
By empowering businesses and industries, expanding the creative landscape for maker spaces, unleashing innovation, and creating opportunities for growth, Monport Laser is at the forefront of revolutionizing the laser engraving field.
Company: Monport Laser
Contact email: official@monportlaser.com
Pre-sales Phone: (+1)332-251-1208
Monport Laser Website: https://monportlaser.com/
Monport Adress: Monport Tech Inc. 300 LENORA ST 878, SEATTLE, WA, 98121-2411, UNITED STATES
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SOURCE Monport Laser | https://www.wafb.com/prnewswire/2023/07/31/monport-laser-unveils-new-gp-series-gi-series-fiber-lasers-redefine-precision-performance/ | 2023-07-31T04:56:40 | 0 | https://www.wafb.com/prnewswire/2023/07/31/monport-laser-unveils-new-gp-series-gi-series-fiber-lasers-redefine-precision-performance/ |
NANJING, China, July 31, 2023 /PRNewswire/ -- Nanjing Leads Biolabs Co., Ltd. (hereinafter referred to as "Leads Biolabs" or "Company") announced today that the National Medical Products Administration (NMPA) and the U.S. Food and Drug Administration (FDA) have approved its first-in-human Investigational New Drug (IND) applications for LBL-034, an anti-GPRC5D/CD3 bispecific antibody invented by Leads Biolabs with global intellectual property rights, for the treatment of relapsed/refractory multiple myeloma. Currently, no GPRC5D-targeting antibody has been approved for marketing.
This is a first-in-human, single-arm, multicenter, open-label, dose-escalation and expansion clinical study, and plans to enroll patients with relapsed/refractory multiple myeloma who have failed prior therapies including but not limited to at least one proteasome inhibitor (PI), one immunomodulator (IMiD) as well as other standard treatments. This study aims to evaluate the safety and tolerability of LBL-034, determine the recommended Phase II dose and assess its efficacy in patients with multiple myeloma.
"Despite recent progress and continuous advancements in multiple myeloma, the time between recurrences has been steadily decreasing, particularly as the number of treatment lines increases. This ultimately leads to emergence of relapsed or refractory multiple myeloma, reaffirming its status as an incurable malignant tumor that poses a serious threat to human life. In light of this challenging reality, the urgent need for more effective and innovative treatment options has never been more evident." said Dr. Charles Cai, Chief Medical Officer of Leads Biolabs, "LBL-034 adopts a unique molecular design, which enables the drug to specifically bind to GPRC5D-expressing tumor cells with high affinity, and reduces the risk of non-specific activation of T-cells, thereby enhancing anti-tumor efficacy and reducing potential risk of immunotoxicity. LBL-034 demonstrated robust anti-tumor activities and good safety profile in pre-clinical studies. We adhere to our tradition of innovation and aim to deliver an important, novel and effective treatment option for patients with poor prognosis of relapsed/refractory multiple myeloma."
About GPRC5D:
G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D) is a C-type 7-channel transmembrane receptor protein. GPRC5D is low expressed in normal human tissues but specifically overexpressed in multiple myeloma. The intensity of GPRC5D expression is an independent prognostic factor in multiple myeloma, and its overexpression is significantly associated with reduced overall survival. Therefore, GPRC5D may be an important potential target for the treatment of plasma cell diseases such as multiple myeloma.
About multiple myeloma:
Multiple myeloma is a malignant plasma cell disease caused by abnormal proliferation of clonal plasma cells, accounting for 10-15% of hematologic malignancies and about 1.4% of all malignancies. It is the second most common hematological malignancy in adults after non-Hodgkin's lymphoma and mostly occurs in the elderly. According to the data released by the World Health Organization (WHO), the number of new cases and deaths of multiple myeloma worldwide in 2020 were 176,000 and 117,000 respectively, and the number of new cases and deaths of multiple myeloma in China were 21,000 and 16,000 respectively. Currently, multiple myeloma is still an incurable malignant tumor, and the five-year survival rate of patients is approximately 24.8% in China, 33.3% in Japan, and 46.7% in the United States. In recent years, with the successful development of proteasome inhibitors (PIs), immunomodulatory drugs (IMiDs), selective nuclear output inhibitors, CD38-targeted antibodies, bispecific antibodies, and CAR-T cell therapies, the tumor response rate and survival prognosis have been significantly improved. However, multiple myeloma remains an unmet clinical need for more effective treatments.
About LBL-034:
LBL-034 is a humanized IgG1 subtype asymmetric bispecific antibody targeting both GPRC5D and CD3 and Leads Biolabs fully owns the worldwide intellectual property rights. LBL-034 induces T-cell-mediated killing of myeloma cells by redirecting CD3+ T-cells to myeloma cells expressing GPRC5D.
LBL-034 has the potential to be a transformative best-in-class GPRC5D-targeted immunotherapy for multiple myeloma. Clinical studies are planned to evaluate the safety and efficacy of LBL-034 in patients with relapsed/refractory multiple myeloma.
Nanjing Leads Biolabs Co., Ltd. is a clinical-stage biotechnology company founded in Nanjing by a team of senior U.S.-trained antibody drug developers. Since 2014, Leads Biolabs has been dedicated to the discovery and development of novel antibody drugs with independent intellectual property rights for the treatment of oncology and other major diseases of high unmet medical needs, particularly the challenges in cancer immunotherapy. Our extensive R&D pipeline consist of more than twenty novel tumor immunotherapy molecules based on monoclonal and bispecific antibody technology platforms. Leads Biolabs is committed to providing safe, effective, accessible and affordable new drugs to address the unmet needs of patients around the world.
For more information, please visit: https://www.leadsbiolabs.com
Business contact: bd@leadsbiolabs.com
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SOURCE LEADS BIOLABS | https://www.wafb.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ | 2023-07-31T04:56:46 | 1 | https://www.wafb.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ |
Partnership adds cryptocurrency as a payment option for merchants using Optty's universal payment platform
SINGAPORE, July 30, 2023 /PRNewswire/ -- Optty, the world's first universal payments platform, today announced a new partnership with Triple-A, a licensed crypto payment gateway, to add cryptocurrency as a payment option on the platform. As the central hub connecting and streamlining a robust global network of Buy Now Pay Later (BNPL) providers, this milestone marks the launch of Optty's sixth payment architecture, further expanding viable payment options for merchants and convenience for their end customers.
Sign-up and integration with Optty is free. To get started, please visit: https://www.optty.com/merchant-account
"As the world's first true universal payments platform, Optty is agnostic and supportive of payments inclusion, a unique position that is designed to help retailers offer more choice than ever at checkout," said Natasha Zurnamer, CEO and founder of Optty. "With one simplified integration, not only can retailers access over 90 BNPLs and local payment methods in over 120 countries — they can now switch on crypto payments, a natural progression in our aim to simplify payments for retailers all over the world."
The first crypto payment gateway to be licensed by the Monetary Authority of Singapore, Triple-A is also licensed in Europe, through Banque de France's ACPR, and registered with the United States Financial Crimes Enforcement Network (FinCEN). Through the collaboration with Triple-A's white label crypto payment gateway, Optty enables retailers and merchants to offer a wide range of payment methods. This allows them to test and learn which payment types best resonate with their customers.
Tapping into diverse consumer payment preferences
With Optty's vast global network of gateways that license the company's unique payment stacks, merchants and retailers can now leverage Triple-A's gateway to accept cryptocurrencies such as Bitcoin (BTC), Ethereum (ETH), Tether (USDT), and USD Coin (USDC). Triple-A's crypto payment gateway is compatible with all crypto wallets, allowing customers to make hassle-free payments using their preferred wallet.
Through real-time crypto-to-fiat conversions facilitated by Triple-A, retailers can receive payments in cryptocurrencies without the need to manage them on their balance sheets and constantly monitor fluctuating exchange rates. Retailers enjoy next-day local currency bank settlements in 50+ currencies, enabling quick access to funds in their preferred currency. Additionally, businesses have the option to offer their customers the convenience of paying through Binance Pay.
Optty already offers Buy Now Pay Later, Debit and Credit, Digital Wallets, Peer to Peer payments, and bank transfer options, and the addition of crypto enables merchants to tap into the spending power of 420 million crypto owners worldwide. Optty plans to further expand payment architectures to a total of nine by the end of 2023.
"We are excited to partner with Optty and bring crypto payments to their merchants," said Eric Barbier, CEO of Triple-A. "This collaboration will help merchants take advantage of the growing demand for cryptocurrency payments, without the hassle of managing crypto assets on their balance sheets."
Disruption through simplification
Previously, retailers and merchants would need to spend a great deal of time and money on complex, one-by-one payment integration processes. Optty changed all this by eliminating it, revolutionizing the way merchants access payments methods globally. Available across ecommerce, IVR, and in-store, it is a true PaaS that offers retailers a simplified integration while providing a seamless and direct commercial partnership channel, enabling an application process with every payment provider in the solution.
About Optty
As a PaaS, Optty is the world's first true universal payments platform that integrates over 90 installment (BNPL) brands — more than any other existing single integration solution globally — and offers six payment architectures, soon to be nine by the end of 2023. Its payments-, partner- and channel-agnostic approach delivers wide payments connectivity globally to schemes, acquirers, gateways and retailers alike and offers a full white-label, customisable interface with hierarchy built in for network expansion ease.
For more information, please visit: https://www.optty.com/
About Triple-A
Triple-A is a licensed crypto payment gateway that helps businesses increase their revenue by enabling crypto payments and payouts, giving them access to the spending power of the fast-growing 420m+ cryptocurrency users.
Triple-A's white label crypto payments solutions allow businesses from all industries to leverage the benefits of the growing crypto market without being exposed to volatility risk or having to handle or convert digital currencies. Their solutions are compatible with all wallets, easy to integrate and offer instant confirmation, locked-in exchange rates and chargeback protection.
Licensed by the Monetary Authority of Singapore (MAS) and trusted by over 15,000 businesses, Triple-A makes accepting crypto payments simple for businesses across the globe.
For more information, please visit https://triple-a.io/.
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SOURCE Optty | https://www.wafb.com/prnewswire/2023/07/31/optty-partners-with-triple-a-expand-payment-architectures-into-cryptocurrencies/ | 2023-07-31T04:56:59 | 1 | https://www.wafb.com/prnewswire/2023/07/31/optty-partners-with-triple-a-expand-payment-architectures-into-cryptocurrencies/ |
More experienced principals leave the profession at higher rates
WASHINGTON, July 31, 2023 /PRNewswire/ -- Roughly 1 in 10 (11 percent) public school principals left the profession between the 2020-21 and 2021-22 school years, according to data from the National Teacher and Principal Survey (NTPS) released today by the National Center for Education Statistics (NCES), the statistical center within the U.S. Department of Education's Institute of Education Sciences (IES).
"Principal attrition is higher in public schools than it was 5 years ago, and veteran public school leaders with more years of experience leave the profession at higher rates than those with less experience," said NCES Commissioner Peggy G. Carr. "Principals are critical supports for a school's teachers and learners, and the country needs leaders in every school who are committed to the success of each student. These data are a valuable snapshot for those at the district and state levels who must address the issue of principal turnover in their schools."
Approximately 80 percent of 2020-21 public school principals remained at the same school one year later ("stayers"), which was lower than the percentage of 2016-17 public school principals who were still at their school 1 year later (82 percent). Six percent of 2020-21 public school principals moved to a different school ("movers"), and 11 percent left the principalship ("leavers"). For private school principals in 2020-21, approximately 83 percent remained at the same school during the following school year, 2 percent moved to a different school, and 10 percent left the principalship.
Additionally, among 2020-21 public school principals who somewhat or strongly agreed they would leave the principalship as soon as possible if they could get a higher paying job (about 25 percent), approximately 73 percent stayed the following school year, while about 15 percent left the profession.
"These data are critical to understanding patterns of principal attrition," said NCES Associate Commissioner Chris Chapman. "We are able to observe how principal attrition has changed over the years, as well as how principal attrition and mobility vary based on characteristics of the principals and their schools."
The report released today includes selected findings from the Principal Follow-up Survey (PFS), a longitudinal component of the National Teacher and Principal Survey (NTPS), which is a nationally representative survey of public and private K-12 schools, principals, and teachers in the 50 states and the District of Columbia. Data were collected from January 2022 through June 2022. The sample included about 6,500 public school principals and about 1,800 private school principals, for a total sample size of about 8,300 principals.
The data were collected as a follow-up to the 2020-21 NTPS to provide attrition and mobility information about principals in K-12 public and private schools. The purpose was to ascertain how many principals from the 2020-21 school year still worked as a principal in the same school 1 year later ("stayer"), how many had moved to become a principal in another school ("mover"), and how many were no longer working as a principal ("leaver").
Key Findings
- Of all public school principals in 2020-21, 11 percent left the profession by the 2021-22 school year. This was higher than in 2016-17, when 10 percent of all public school principals had left the profession since 2015-16, but not measurably different from the 2012-13 school year, when 12 percent of all public school principals had left the profession since the previous school year, or from 2008-09, when 12 percent of all public schools had left the profession since the previous school year.
- Of all public school principals in 2020-21 with more than 10 years of experience as a principal at any school, 15 percent left the profession by the 2021-22 school year. Of those principals with 10 years or more experience as a principal in their current school, 16 percent left the profession.
- A higher percentage of school principals 55 years of age or older left the profession compared to principals between 45-54 years of age.
- Among the 9 percent of 2020-21 public school principals with a salary of less than $75,000, 76 percent remained at the same school during the 2021–22 school year, 7 percent moved to a different school, and 13 percent left the principalship.
- Among the 33 percent of 2020-21 public school principals with a salary of $115,000 or more, 81 percent remained at the same school during the 2021-22 school year, 6 percent moved to a different school, and 10 percent left the principalship.
- Among the 62 percent of 2020-21 private school principals with a salary of less than $75,000, 81 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 10 percent left the principalship.
- Among the 13 percent of 2020-21 private school principals with a salary of $115,000 or more, 85 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 8 percent left the principalship.
The National Center for Education Statistics, a principal agency of the U.S. Federal Statistical System, is the statistical center of the U.S. Department of Education and the primary federal entity for collecting and analyzing data related to education in the U.S. and other nations. NCES fulfills a congressional mandate to collect, collate, analyze, and report complete statistics on the condition and progress of American education; conduct and publish reports; and review and report on education activities internationally.
Follow NCES on Twitter, Facebook, LinkedIn, and YouTube and subscribe to the NCES Newsflash to receive email notifications when new data is released.
The Institute of Education Sciences (IES) is the independent and nonpartisan statistics, research, and evaluation arm of the U.S. Department of Education. Its mission is to provide scientific evidence on which to ground education practice and policy and to share this information in formats that are useful and accessible to educators, parents, policymakers, researchers, and the public.
CONTACT: Josh Delarosa, National Center for Education Statistics, ARIS.NCES@ed.gov
James Elias, Hager Sharp, jelias@hagersharp.com
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SOURCE National Center for Education Statistics | https://www.wafb.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ | 2023-07-31T04:57:05 | 0 | https://www.wafb.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ |
HANOI, Vietnam, July 31, 2023 /PRNewswire/ -- SeABank's stock (SSB) has been officially selected by the Ho Chi Minh City Stock Exchange (HOSE) to be included in the VN30-Index basket - an index representing the top 30 stocks with the highest market capitalization and liquidity listed on the HOSE.
At the end of the trading session on July 28, 2023, the closing price of SSB's stock was 29,700 VND per share, bringing SeABank's market capitalization to over 72,875 billion VND, equivalent to nearly 3.07 billion USD.
According to the press release, on July 17, 2023, HOSE announced the portfolio of stocks included in the VN30 and VN-Finlead indexes, which would be effective from August 7, 2023. SSB was chosen to be included in the VN30 basket as it met the requirements set by the HOSE Index Rules. With an average market capitalization of nearly 65,000 billion Vietnamese dongs over the past six months, SSB is one of the largest capitalized stocks among those not included in the previous VN30 basket.
Throughout its operations, SeABank prioritizes transparency by providing information to shareholders, partners, and customers, complying with legal regulations, and following the directives of the Government and the State Bank of Vietnam to stabilize the market, ensure smooth operations, and promote business activities, thereby contributing to the country's socio-economic development.
SeABank's stock (SSB) was officially listed on the HOSE on March 24, 2021, with a reference price of 16,800 Vietnamese dongs per share on its first trading day. It has consistently experienced stable growth since then. In June 2023, SeABank successfully issued shares for dividend payment and additional capital from shareholder funds (bonus shares) with a total ratio of 20.3% to increase its charter capital to 24,537 billion Vietnamese dong.
Previously, SSB was also added to the Morgan Stanley Capital Index (MSCI) Frontier Markets Index starting from March 1, 2023. According to experts, stocks included in the MSCI Frontier Markets Index may be targeted by ETF (Exchange Traded Fund) funds that track frontier market stocks. Some funds use this index as a reference for investment or replicate its portfolio.
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SOURCE SeABank | https://www.wafb.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ | 2023-07-31T04:57:12 | 0 | https://www.wafb.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ |
Former Alabama golfers Lee Hodges and Davis Shore were winners on Sunday, with Hodges posting his first PGA Tour victory and Shore getting his first PGA Tour Canada victory.
But Auburn was not left out of the golf celebrations on Sunday.
A four-year player for the Tigers, Trace Crowe won the NV5 Invitational presented by Old National Bank at the Glen Club in Glenview, Illinois, for his first victory on the Korn Ferry Tour.
Crowe defeated Patrick Fishburn on the second hole of a sudden-death playoff to win the tournament after both golfers were tied at 25-under par at the end of the fourth round.
Crowe has played on the Korn Ferry Tour for two seasons, and Sunday’s victory was a bolt out of the blue. In his 28 starts on the circuit before Sunday, Crowe had posted two top-25 finishes, with his best showing coming this season at the Ledges in Huntsville, where he came in 11th at the Hometown Lenders Championship.
After missing seven cuts in his 11 starts this season, Crowe entered Sunday’s tournament 139th on the Korn Ferry Tour points list. The victory shot him to No. 35. The top 30 golfers on the Korn Ferry Tour points list at the end of the season receive PGA Tour cards.
“I’m still in shock,” Crowe said. “It’s a crazy feeling. It’s been a long, tough, interesting season. To be standing here -- it still hasn’t sunk in. I’m just blown away just how good everyone is, and I feel like I just played unreal the last couple days.”
Crowe had a two-stroke lead playing in the final group on the 18th hole on Sunday. But Fishburn sank a 40-foot eagle putt on the par-5 finishing hole to force a playoff.
Both golfers birdied the 18th on the first playoff hole. Playing the 18th again, Crowe had a par while Fishburn took a bogey to end the tournament.
Crowe became the fourth winner in Korn Ferry Tour history to overcome a triple bogey in the final round. That happened on the par-4 second hole, before Crowe birdied eight of the next 12 holes.
Crowe earned the winner’s purse of $180,000, which boosted his Korn Ferry Tour winnings for the season to $251,161.
Mark Inabinett is a sports reporter for Alabama Media Group. Follow him on Twitter at @AMarkG1. | https://www.al.com/sports/2023/07/former-auburn-golfer-posts-his-first-pro-victory.html | 2023-07-31T04:58:32 | 1 | https://www.al.com/sports/2023/07/former-auburn-golfer-posts-his-first-pro-victory.html |
Erratic winds challenge firefighters battling two major California blazes
MOJAVE NATIONAL PRESERVE, Calif. (AP) — A massive wildfire burning out of control in California’s Mojave National Preserve was spreading rapidly amid erratic winds, while firefighters reported progress against another major blaze to the southwest that prompted evacuations.
The York Fire that erupted Friday near the remote Caruthers Canyon area of the vast wildland preserve crossed the state line into Nevada on Sunday and sent smoke further east into the Las Vegas Valley.
Wind-driven flames 20 feet (6 meters) high in some spots charred more than 110 square miles (284 square kilometers) of desert scrub, juniper and Joshua tree woodland, according to an incident update. There was zero containment.
“The dry fuel acts as a ready ignition source, and when paired with those weather conditions it resulted in long-distance fire run and high flames, leading to extreme fire behavior,” the update said. No structures were threatened.
To the southwest, the Bonny Fire was holding steady at about 3.4 square miles (8.8 square kilometers) in rugged hills of Riverside County. More than 1,300 people were ordered to evacuate their homes Saturday near the community of Aguanga that is home to horse ranches and wineries.
Gusty winds and the chance of thunderstorms into Monday will heighten the risk of renewed growth, the California Department of Forestry and Fire Protection said in a statement.
One firefighter was injured in the blaze, which was 5% contained.
Copyright 2023 The Associated Press. All rights reserved. | https://www.kfyrtv.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ | 2023-07-31T04:58:36 | 1 | https://www.kfyrtv.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ |
Black Achievers program helps underserved students
LEXINGTON, Ky. (WKYT) - The Black Achievers program at the North Lexington YMCA is helping underserved students plan for college and beyond.
“It’s a great opportunity for him to get exposure to different careers, different professionals,” said Candis Tingle, a volunteer for Black Achievers.
Her son, 10-year-old Avery Garrett, will be joining Black Achievers this year.
“I’m looking forward to learning a bunch of different things, and maybe learn new skills,” said Garrett.
Every second and fourth Saturday of the school year, participating 6th-12th graders will learn from experts in their desired fields and discuss their futures.
They are resources program director Marley Bush personally appreciates.
“I’m a first-generation college student, so I would’ve personally, as a young Black woman, would’ve generously benefitted from this program myself,” said Bush.
After participating in the program, students can get some extra help paying for college.
“Our students who actually go through that entire process as seniors are rewarded for their efforts with some scholarship funding,” said Jonathan Kohn, senior director of mission advancement at the YMCA of Central Kentucky.
As Tingle’s son Avery begins his time with Black Achievers, Tingle hopes the community sees the value in supporting the next generation.
“I would just like more people to get involved in the program because it is such a benefit to get involved in the program,” said Tingle. “It is such a wonderful benefit for our children.”
Spots for the Black Achievers program are still open and can be applied to using the link.
Copyright 2023 WKYT. All rights reserved. | https://www.wkyt.com/2023/07/31/black-achievers-program-helps-underserved-students/ | 2023-07-31T04:58:35 | 0 | https://www.wkyt.com/2023/07/31/black-achievers-program-helps-underserved-students/ |
Erratic winds challenge firefighters battling two major California blazes
MOJAVE NATIONAL PRESERVE, Calif. (AP) — A massive wildfire burning out of control in California’s Mojave National Preserve was spreading rapidly amid erratic winds, while firefighters reported progress against another major blaze to the southwest that prompted evacuations.
The York Fire that erupted Friday near the remote Caruthers Canyon area of the vast wildland preserve crossed the state line into Nevada on Sunday and sent smoke further east into the Las Vegas Valley.
Wind-driven flames 20 feet (6 meters) high in some spots charred more than 110 square miles (284 square kilometers) of desert scrub, juniper and Joshua tree woodland, according to an incident update. There was zero containment.
“The dry fuel acts as a ready ignition source, and when paired with those weather conditions it resulted in long-distance fire run and high flames, leading to extreme fire behavior,” the update said. No structures were threatened.
To the southwest, the Bonny Fire was holding steady at about 3.4 square miles (8.8 square kilometers) in rugged hills of Riverside County. More than 1,300 people were ordered to evacuate their homes Saturday near the community of Aguanga that is home to horse ranches and wineries.
Gusty winds and the chance of thunderstorms into Monday will heighten the risk of renewed growth, the California Department of Forestry and Fire Protection said in a statement.
One firefighter was injured in the blaze, which was 5% contained.
Copyright 2023 The Associated Press. All rights reserved. | https://www.azfamily.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ | 2023-07-31T04:58:36 | 0 | https://www.azfamily.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ |
Erratic winds challenge firefighters battling two major California blazes
MOJAVE NATIONAL PRESERVE, Calif. (AP) — A massive wildfire burning out of control in California’s Mojave National Preserve was spreading rapidly amid erratic winds, while firefighters reported progress against another major blaze to the southwest that prompted evacuations.
The York Fire that erupted Friday near the remote Caruthers Canyon area of the vast wildland preserve crossed the state line into Nevada on Sunday and sent smoke further east into the Las Vegas Valley.
Wind-driven flames 20 feet (6 meters) high in some spots charred more than 110 square miles (284 square kilometers) of desert scrub, juniper and Joshua tree woodland, according to an incident update. There was zero containment.
“The dry fuel acts as a ready ignition source, and when paired with those weather conditions it resulted in long-distance fire run and high flames, leading to extreme fire behavior,” the update said. No structures were threatened.
To the southwest, the Bonny Fire was holding steady at about 3.4 square miles (8.8 square kilometers) in rugged hills of Riverside County. More than 1,300 people were ordered to evacuate their homes Saturday near the community of Aguanga that is home to horse ranches and wineries.
Gusty winds and the chance of thunderstorms into Monday will heighten the risk of renewed growth, the California Department of Forestry and Fire Protection said in a statement.
One firefighter was injured in the blaze, which was 5% contained.
Copyright 2023 The Associated Press. All rights reserved. | https://www.1011now.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ | 2023-07-31T04:58:40 | 1 | https://www.1011now.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ |
Erratic winds challenge firefighters battling two major California blazes
MOJAVE NATIONAL PRESERVE, Calif. (AP) — A massive wildfire burning out of control in California’s Mojave National Preserve was spreading rapidly amid erratic winds, while firefighters reported progress against another major blaze to the southwest that prompted evacuations.
The York Fire that erupted Friday near the remote Caruthers Canyon area of the vast wildland preserve crossed the state line into Nevada on Sunday and sent smoke further east into the Las Vegas Valley.
Wind-driven flames 20 feet (6 meters) high in some spots charred more than 110 square miles (284 square kilometers) of desert scrub, juniper and Joshua tree woodland, according to an incident update. There was zero containment.
“The dry fuel acts as a ready ignition source, and when paired with those weather conditions it resulted in long-distance fire run and high flames, leading to extreme fire behavior,” the update said. No structures were threatened.
To the southwest, the Bonny Fire was holding steady at about 3.4 square miles (8.8 square kilometers) in rugged hills of Riverside County. More than 1,300 people were ordered to evacuate their homes Saturday near the community of Aguanga that is home to horse ranches and wineries.
Gusty winds and the chance of thunderstorms into Monday will heighten the risk of renewed growth, the California Department of Forestry and Fire Protection said in a statement.
One firefighter was injured in the blaze, which was 5% contained.
Copyright 2023 The Associated Press. All rights reserved. | https://www.wkyt.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ | 2023-07-31T04:58:42 | 0 | https://www.wkyt.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ |
Phoenix wildlife center receives up to 150 injured animals a day during heat, monsoons
PHOENIX (3TV/CBS 5) - A wildlife rescue in Phoenix is seeing a huge increase in animal drop-offs, according to staff. They say the busiest days are after extreme temperatures or high winds from the monsoon. Liberty Wildlife sees about 10,000 animals per year but says it’s already treated around 8,000 this year, partly because of how hot it’s been.
The animals the nonprofit cares for are all native and well-adapted to heat. “The problem with this year is that that heat has been so high, so many days in a row,” said Laura Hackett, a biologist for the rescue.
They use many methods during the summer months to keep animals cool. “They always have access to water. Some of them have larger pools that they like to get in and take baths. We’re also having our volunteers come in and do extra shifts where they come in at 2:30 and 4:30 and literally walk down the aisles and hose our birds off,” she said.
Still, the relentless heat is causing issues, especially with the swamp coolers. “With the fact that they’re running 12 hours a day and just constantly going, we’re seeing them wear down, break down, circuits are getting blown,” she said.
Hackett says spring and summer are the busiest times of year for the rescue, and she expects the rain and strong dust storms during the monsoon will make it even busier. “Especially with the monsoon storms start coming in, we get winds. So we start seeing them fall onto the ground where of course our pavement is hot,” Hackett said. “We can get upwards of 150 animals brought in just on that day alone.”
Hackett says the facility also works like a hospital for people, with a triage room, intensive care units and orphan care. “We’re depending on the public of Arizona to be our ambulances and find those animals if they’ve gotten into a stressful situation, whether they’ve been knocked to the ground or succumbing to the heat,” she said.
Liberty Wildlife has about 300 volunteers, and Hackett says the increase in workload would be unmanageable without them. Right now, the center limits the type of birds it takes in because of the avian flu. If you encounter an animal needing help, visit their website on Emergency Care.
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Copyright 2023 KTVK/KPHO. All rights reserved. | https://www.azfamily.com/2023/07/31/phoenix-wildlife-center-receives-up-150-injured-animals-day-during-heat-monsoons/ | 2023-07-31T04:58:42 | 1 | https://www.azfamily.com/2023/07/31/phoenix-wildlife-center-receives-up-150-injured-animals-day-during-heat-monsoons/ |
Husker fans flock to Football Fan Day
Published: Jul. 30, 2023 at 11:47 PM CDT|Updated: 9 minutes ago
LINCOLN, Neb. (KOLN) - The Nebraska Football Team hosted their annual “Football Fan Day” inside the Hawks Championship Center. Hundreds of Nebraska fans attended to meet their favorite players, buy merch, and receive autographs.
The players and position coaches were situated at tables in-line with the yard marker lines. Fans went along the tables receiving 1 autograph from every player in attendance.
Fans were able to bring their own items and memorabilia to be signed. With this ability, there was many unique items being autographed.
Nebraska Fall Football Camp begins Monday, July 31, 2023.
Copyright 2023 KOLN. All rights reserved. | https://www.1011now.com/2023/07/31/husker-fans-flock-football-fan-day/ | 2023-07-31T04:58:46 | 1 | https://www.1011now.com/2023/07/31/husker-fans-flock-football-fan-day/ |
Firefighters tackle structure fire in Lexington
Published: Jul. 30, 2023 at 11:55 PM EDT|Updated: 1 hour ago
LEXINGTON, Ky. (WKYT) - Lexington Firefighters were called out to a structure fire around 9:00 Sunday evening.
The home was located along the 3500 block of Milam Lane. Flames were visible from the front of the building and fire was showing on the first and second floors.
The LFD Public Information Officer tells WKYT residents and pets were evacuated and no injuries have been reported.
This story will be updated as more information becomes available.
Copyright 2023 WKYT. All rights reserved. | https://www.wkyt.com/2023/07/31/firefighters-tackle-structure-fire-lexington/ | 2023-07-31T04:59:10 | 1 | https://www.wkyt.com/2023/07/31/firefighters-tackle-structure-fire-lexington/ |
Harrison County veteran farmer receives grant to expand operations
CYNTHIANA, Ky. (WKYT) - For new farmer Lauren Simmons, existing in a male-dominated field is nothing new.
“Its not uncommon when you go to any type of feed store or tractor shop or whatever, my husband, he’s a manly man, so naturally they assume that he’s the one that kind of runs the farm and he’s the veteran, but he’s quick to say, ‘no my wife, she’s the one who’s the veteran.’” said Simmons, owner and operator of Brownings Farm in Cynthiana.
Simmons served six years in the United States Coast Guard, something she said has benefited her farming career as well.
“The dynamics of what the military offered, which is really hard work and hard work under pressure. It shaped me,” she said.
As a veteran, Simmons was eligible to receive $5,000 through the Farmer Veteran Coalition’s Fellowship Fund.
The money will allow her to expand Brownings Farm and provide even more goods to the people of Harrison County.
“I applied for the grant for one of the pieces of equipment that we were missing which was a post driver, and that will allow us to turn all of this into pastures that we can rotationally graze,” she added.
Simmons said she’s thrilled to be a part of an organization that not only gives funding to veteran farmers, but supports their entire operation.
“The types of things that you have to do on a farm can really translate over to your training, and so I think these programs are huge because they allow people to do something that will heal them,” she said.
Simmons also said grant funding like this can really help small and up-and-coming farms like her by preventing them from going into debt with costly business loans.
Copyright 2023 WKYT. All rights reserved. | https://www.wkyt.com/2023/07/31/harrison-county-veteran-farmer-receives-grant-expand-operations/ | 2023-07-31T04:59:10 | 1 | https://www.wkyt.com/2023/07/31/harrison-county-veteran-farmer-receives-grant-expand-operations/ |
CHICAGO — It’s full steam ahead for Monday morning, when at least 200 workers at Loretto Hospital on the City’s Southwest Side, will walk off the job.
“The strike will start tomorrow morning,” said Erica Bland-Durosinmi, executive vice president of SEIU Healthcare, the union representing the workers who are prepared to strike. “We’ve been at the table … proposals have gone back and forth, but we’ve been unable to reach an agreement at this time.”
Mental health workers, radiology technicians and housekeepers make up the bulk of the group. The workers claim they’re underpaid and understaffed, which is reflected by the turnover rate at Loretto Hospital — a number that stands at nearly 60%.
“People don’t stay because they’re not investing in the staff in a real way,” Bland-Durosinmi said. “It’s unfortunate that we’ve gotten here, where management is unwilling to bargain in good faith.”
Bland-Durosinmi told WGN that some pay raises and additional personal days have been offered by the hospital, but their offers have not been substantial enough.
“During the pandemic, we told workers, they are heroes and they deserved everything,” Bland-Durosinmi said. “Now, here we are in a moment where that can be honored with a contract that workers have every right to negotiate, and management is not showing that same respect and sentiment in these negotiations.”
Beyond proper compensation and time-off for workers at Loretto Hospital, Bland-Durosinmi also said familiar faces are needed for their patients who are experiencing traumatic incidents, making the impact of contract negotiations falling through felt far beyond just the pocketbook.
“Most of the people who show up in the ER are people who are having a mental health emergency or are in crisis,” Bland-Durosinmi said. “Those people need to see someone familiar to them.”
In a statement released Sunday evening, a spokesperson for Loretto Hospital told WGN in part:
“[We] made another counteroffer today that addresses recruitment and retention concerns including new starting rates and up to a three-year cumulative 12-percent wage increase for current team members. Loretto Hospital also agreed to the Juneteenth holiday request. We are hopeful that the latest, sustainable proposal will lead to a new collective bargaining agreement.”
Barring Loretto Hospital’s latest proposal being accepted, the strike is still planned to begin Monday morning at 7 a.m. | https://wgntv.com/news/chicago-news/hundreds-of-loretto-hospital-workers-set-to-strike/ | 2023-07-31T05:00:18 | 1 | https://wgntv.com/news/chicago-news/hundreds-of-loretto-hospital-workers-set-to-strike/ |
LAKE MICHIGAN WATER TEMPS
- WGN weekly climate report: Just a few days left in the 7th month of 2023 and this last week we saw our hottest week of the year so far—with our longest string of 90-plus degrees this summer. A stretch that ended with some severe thunderstorms and two confirmed tornadoes in Kankakee County on Friday. While we also saw another day (June 24th) with a high of 93 degrees—the humidity was far higher in the last week. So while the Friday air temperature was 93, it felt like 100 to 110 in many places with the humidity included in the statistic we call the ‘heat index.’
- Chicagoland has been lacking in days above 90 so far this year, we’re up to 13 now at O’Hare which is about half of what we saw by last year at this time and putting us close to hitting the normal number of days of 90 or warmer likely in August. We still have not hit 100 degrees at O’Hare since July of 2012, though we hit triple-digit heat at Midway a couple of times last year.
- What we have not been lacking this month is rainfall. More than 7 inches at O’Hare is more than four inches of rain more than a typical July. And after a record dry spring, Midway Airport is reporting the wettest month of July ever reported in records that go back almost 100 years.
- Despite the recent rainfall—which have been flooding rains many times this month—many of us still under what’s considered drought conditions by the USDA’s drought monitor. That’s because it takes a lot of rain repeatedly to come back from drought conditions. Released weekly, this week’s current report (which would not include any of Friday’s heavy rains) still has most of Cook County extended out towards the southwest suburbs under what’s considered the lowest possible drought tier “abnormally dry.” The worst-off place is further north along the Wisconsin state line where the drought conditions are considered “severe.” It’s much better off than places on the Great Plains that are experiencing another summer of severe drought conditions.
- The week ahead looks to be mostly seasonal temperature-wise. Many of the computer forecast models had the “dome of heat” expanding back into the Great Lakes region. But, the last few days those forecast models have backed off a bit, instead putting us in the “ring-of-fire” pattern that goes around the heat dome providing some active weather getting into Wednesday/Thursday and warmer temps but not quite likely into the 90s.
TODAY AND THE EXTENDED OUTLOOK
- Another beautiful summer day for Chicagoland! Highs today close to 80 inland and even some lower humidity expected this afternoon too. Temps in the lower 70s on the beaches today with a water temp near 73 degrees. Tonight clear skies and seasonal overnight temps in the city and lower 60s in the suburbs. Monday looks like more sunshine and high temps right near where they should be for the last day of July.
- We do warm things up a bit with the “dome of heat” over the southern and southwestern U.S. showing some signs of expanding into the Great Lakes region on Wednesday/Thursday. With the most recent computer forecast model runs, it puts Chicago not quite in the dry and hot dome itself but more in the “ring-of-fire” pattern where showers and thunderstorms go up and over the heat dome. Those thunderstorms could fend off the hottest temps and give us an active weather pattern for Wednesday/Thursday in particular. Cooler and more comfortable weather look likely for next weekend. Enjoy! | https://wgntv.com/weather/weather-blog/chicago-not-quite-in-the-dry-and-hot-dome-but-in-the-ring-of-fire-pattern-where-showers-and-thunderstorms-go-up-and-over-the-heat-dome/ | 2023-07-31T05:00:24 | 1 | https://wgntv.com/weather/weather-blog/chicago-not-quite-in-the-dry-and-hot-dome-but-in-the-ring-of-fire-pattern-where-showers-and-thunderstorms-go-up-and-over-the-heat-dome/ |
Six migrant workers were struck Sunday afternoon by an SUV in a Walmart parking lot in North Carolina from what police are calling "an intentional assault with a vehicle."
"All six were transported to Atrium Health – Lincoln with various injuries. None of the injuries appear to be life threatening," the Lincolnton Police Department said in a Facebook post.
Police say they're still looking for the vehicle and driver involved in the incident, which they said took place at 1:17 pm ET. In the Facebook post, they describe the vehicle as an older model SUV with a luggage rack, and the driver as an older white male.
The motive for the attack is also still under investigation. Police told NPR via telephone late Sunday there is no further information.
Lincolnton is a small city of some 11,800 people located about an hour outside of Charlotte.
Copyright 2023 NPR. To see more, visit https://www.npr.org. | https://www.kanw.com/npr-news/2023-07-30/an-suv-strikes-6-migrant-workers-in-walmart-parking-lot-in-north-carolina | 2023-07-31T05:00:42 | 0 | https://www.kanw.com/npr-news/2023-07-30/an-suv-strikes-6-migrant-workers-in-walmart-parking-lot-in-north-carolina |
Sears and Murph go back and forth on more topics from the week of sports.
Faceoff: Colorado, Pac 12, Fleck, Harbaugh, Uwazurike, Oppenheimer
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Subscribe Now | https://who13.com/sports/faceoff-colorado-pac-12-fleck-harbaugh-uwazurike-oppenheimer/ | 2023-07-31T05:01:45 | 0 | https://who13.com/sports/faceoff-colorado-pac-12-fleck-harbaugh-uwazurike-oppenheimer/ |
Six migrant workers were struck Sunday afternoon by an SUV in a Walmart parking lot in North Carolina from what police are calling "an intentional assault with a vehicle."
"All six were transported to Atrium Health – Lincoln with various injuries. None of the injuries appear to be life threatening," the Lincolnton Police Department said in a Facebook post.
Police say they're still looking for the vehicle and driver involved in the incident, which they said took place at 1:17 pm ET. In the Facebook post, they describe the vehicle as an older model SUV with a luggage rack, and the driver as an older white male.
The motive for the attack is also still under investigation. Police told NPR via telephone late Sunday there is no further information.
Lincolnton is a small city of some 11,800 people located about an hour outside of Charlotte.
Copyright 2023 NPR. To see more, visit https://www.npr.org. | https://www.wboi.org/npr-news/2023-07-30/an-suv-strikes-6-migrant-workers-in-walmart-parking-lot-in-north-carolina | 2023-07-31T05:01:45 | 0 | https://www.wboi.org/npr-news/2023-07-30/an-suv-strikes-6-migrant-workers-in-walmart-parking-lot-in-north-carolina |
Mr. Soundoff Says – 2 weeks ago 2-time NCAA champion and Olympic gold medalist Gable Steveson got Hawkeye and Gopher fans all riled up by tweeting out cryptic posts about his future.
Steveson led everyone on to believe he was returning to college, either at Iowa or Minnesota.
He’s not coming back. Instead he announced he’s staying in the WWE. John Sears says the whole charade was lame. | https://who13.com/sports/mr-soundoff-says-steveson-social-media-stunt-was-lame/ | 2023-07-31T05:01:51 | 0 | https://who13.com/sports/mr-soundoff-says-steveson-social-media-stunt-was-lame/ |
Brock Purdy puts 49ers Nation on BrockWatch, and tells us why he remains poised, no matter what.
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Brock Purdy puts 49ers Nation on BrockWatch, and tells us why he remains poised, no matter what.
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Watch for us in your inbox.
Subscribe Now | https://who13.com/sports/soundoff/murphys-law/murphys-law-mr-irrelevant-to-mr-relevant/ | 2023-07-31T05:01:57 | 1 | https://who13.com/sports/soundoff/murphys-law/murphys-law-mr-irrelevant-to-mr-relevant/ |
At Zearing Days, the WHO 13 softball team humbly crushed the unnamed competition by the one-sided score of 11-0, though all involved say, “It’s not about who wins and who loses. Though, it should be noted, we did win.”
No team members were available for additional comments.
WHO 13 softball team dominates Zearing Days competition, remains humble
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Subscribe Now | https://who13.com/sports/soundoff/who-13-softball-team-dominates-zearing-days-competition-remains-humble/ | 2023-07-31T05:02:03 | 0 | https://who13.com/sports/soundoff/who-13-softball-team-dominates-zearing-days-competition-remains-humble/ |
San Francisco (CNN) — In a complaint, the city of San Francisco says they have visited Twitter headquarters twice since Friday regarding the new flashing “X” sign on top of the building.
According to the complaint, a notice of violation (NOV) was issued for work without a permit for the new sign that adorns the building where the social media platform’s headquarters is located.
Owner Elon Musk rebranded Twitter and its iconic bird logo as X last week, as CNN previously reported. He tweeted video of the building with the new flashing “X” logo on Saturday saying, “Our HQ in San Francisco tonight.”
“NOV issued for work without permit. Site visited by MH and spoke with Tweeter (sic) representatives and Building maintenance engineer representatives. I explained BID’s complaint investigation process and requested access to roof area. Tweeter (sic) representative decline to provide access but did explain that the structure is a temporary lighted sign for an event. I explained to all representatives that the NOV requires the structure to be remove with a building permit or legalize,” the complaint reads.
The complaint also noted that on Saturday another attempt was made to access the roof but was also denied.
Patrick Hannan, a spokesperson for the city’s Department of Building Inspection told the Washington Post that “to ensure consistency with the historic nature of the building and to ensure the new additions are safely attached to the sign,” the city requires a permit to approve new letters or symbols on a sign, the paper reported.
CNN has reached out to the City of San Francisco and X for comment.
According to the city’s website, a notice of violation can incur fees, including permit and investigation fees. It is unknown what fees X could face. | https://www.channel3000.com/news/money/san-francisco-s-complaint-against-twitter-says-flashing-x-sign-put-up-without-a-permit/article_8f483bba-444d-55b2-9997-921d4df0b2cc.html | 2023-07-31T05:02:07 | 1 | https://www.channel3000.com/news/money/san-francisco-s-complaint-against-twitter-says-flashing-x-sign-put-up-without-a-permit/article_8f483bba-444d-55b2-9997-921d4df0b2cc.html |
Canaries thumped by Lake Country in series rubber game
Birds fall 15-6 giving up 44 runs in losing two out of three this weekend
SIOUX FALLS, S.D. (Dakota News Now) - The Canaries scored five first inning runs but Lake Country came roaring back to rally past the Birds 15-6 on Sunday.
Mike Hart opened the scoring with a sacrifice fly before Darnell Sweeney ripped an RBI single. Jabari Henry raced home on a wild pitch and Wellington Dotel followed with a two-run double before Lake Country could escape the inning.
The 5-0 lead held until the top of the fifth when the DockHounds belted a two-run homerun. Lake Country struck for five runs in the sixth inning to go in front for good before scoring twice more in the seventh.
Sioux Falls got a run back in the bottom half when Trevor Achenbach singled to bring home Sweeney but the DockHounds responded with a six-run eighth inning, punctuated by a grand slam from former big leaguer Curtis Terry.
Achenbach finished with four hits and Sweeney added three as the Canaries dip to 31-38 overall. The Birds will open a six-game roadtrip Tuesday night in Gary.
Copyright 2023 KSFY. All rights reserved. | https://www.dakotanewsnow.com/2023/07/31/canaries-thumped-by-lake-country-series-rubber-game/ | 2023-07-31T05:02:44 | 0 | https://www.dakotanewsnow.com/2023/07/31/canaries-thumped-by-lake-country-series-rubber-game/ |
Dell Rapids clinches spot in State B Championship with win over host Redfield
Post 65 wins 8-5 to remain unbeaten in tournament
REDFIELD, S.D. (Dakota News Now) - As they did the last time the State B Legion Baseball Tournament was played in Redfield, Dell Rapids Post 65 will play for the State Championship on Tuesday.
Dells scored three runs in the third inning and five more in the fourth to lift themselves to an 8-5 semifinal win over host Redfield on Friday night at the State B Legion Baseball Tournament to clinch a spot in the championship game on Tuesday.
Click on the video viewer for tonight’s highlights!
In other action Elk Point-Jefferson eliminated Salem-Montrose-Canova 5-3 and Tabor knocked out Clark/Willow Lake 13-1.
Monday’s State B Tournament action will start at 4:00 PM with an elimination game between Elk Point-Jefferson and Redfield. 30 minutes after the conclusion of that game Tabor will play Dell Rapids. Should Dell Rapids lose it would mean three one-loss teams would advance to Tuesday’s championship, scheduled to start at 1:00 PM.
Copyright 2023 KSFY. All rights reserved. | https://www.dakotanewsnow.com/2023/07/31/dell-rapids-clinches-spot-state-b-championship-with-win-over-host-redfield/ | 2023-07-31T05:02:50 | 1 | https://www.dakotanewsnow.com/2023/07/31/dell-rapids-clinches-spot-state-b-championship-with-win-over-host-redfield/ |
Erratic winds challenge firefighters battling two major California blazes
MOJAVE NATIONAL PRESERVE, Calif. (AP) — A massive wildfire burning out of control in California’s Mojave National Preserve was spreading rapidly amid erratic winds, while firefighters reported progress against another major blaze to the southwest that prompted evacuations.
The York Fire that erupted Friday near the remote Caruthers Canyon area of the vast wildland preserve crossed the state line into Nevada on Sunday and sent smoke further east into the Las Vegas Valley.
Wind-driven flames 20 feet (6 meters) high in some spots charred more than 110 square miles (284 square kilometers) of desert scrub, juniper and Joshua tree woodland, according to an incident update. There was zero containment.
“The dry fuel acts as a ready ignition source, and when paired with those weather conditions it resulted in long-distance fire run and high flames, leading to extreme fire behavior,” the update said. No structures were threatened.
To the southwest, the Bonny Fire was holding steady at about 3.4 square miles (8.8 square kilometers) in rugged hills of Riverside County. More than 1,300 people were ordered to evacuate their homes Saturday near the community of Aguanga that is home to horse ranches and wineries.
Gusty winds and the chance of thunderstorms into Monday will heighten the risk of renewed growth, the California Department of Forestry and Fire Protection said in a statement.
One firefighter was injured in the blaze, which was 5% contained.
Copyright 2023 The Associated Press. All rights reserved. | https://www.weau.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ | 2023-07-31T05:02:53 | 0 | https://www.weau.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ |
Erratic winds challenge firefighters battling two major California blazes
MOJAVE NATIONAL PRESERVE, Calif. (AP) — A massive wildfire burning out of control in California’s Mojave National Preserve was spreading rapidly amid erratic winds, while firefighters reported progress against another major blaze to the southwest that prompted evacuations.
The York Fire that erupted Friday near the remote Caruthers Canyon area of the vast wildland preserve crossed the state line into Nevada on Sunday and sent smoke further east into the Las Vegas Valley.
Wind-driven flames 20 feet (6 meters) high in some spots charred more than 110 square miles (284 square kilometers) of desert scrub, juniper and Joshua tree woodland, according to an incident update. There was zero containment.
“The dry fuel acts as a ready ignition source, and when paired with those weather conditions it resulted in long-distance fire run and high flames, leading to extreme fire behavior,” the update said. No structures were threatened.
To the southwest, the Bonny Fire was holding steady at about 3.4 square miles (8.8 square kilometers) in rugged hills of Riverside County. More than 1,300 people were ordered to evacuate their homes Saturday near the community of Aguanga that is home to horse ranches and wineries.
Gusty winds and the chance of thunderstorms into Monday will heighten the risk of renewed growth, the California Department of Forestry and Fire Protection said in a statement.
One firefighter was injured in the blaze, which was 5% contained.
Copyright 2023 The Associated Press. All rights reserved. | https://www.wcjb.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ | 2023-07-31T05:02:56 | 0 | https://www.wcjb.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ |
Erratic winds challenge firefighters battling two major California blazes
MOJAVE NATIONAL PRESERVE, Calif. (AP) — A massive wildfire burning out of control in California’s Mojave National Preserve was spreading rapidly amid erratic winds, while firefighters reported progress against another major blaze to the southwest that prompted evacuations.
The York Fire that erupted Friday near the remote Caruthers Canyon area of the vast wildland preserve crossed the state line into Nevada on Sunday and sent smoke further east into the Las Vegas Valley.
Wind-driven flames 20 feet (6 meters) high in some spots charred more than 110 square miles (284 square kilometers) of desert scrub, juniper and Joshua tree woodland, according to an incident update. There was zero containment.
“The dry fuel acts as a ready ignition source, and when paired with those weather conditions it resulted in long-distance fire run and high flames, leading to extreme fire behavior,” the update said. No structures were threatened.
To the southwest, the Bonny Fire was holding steady at about 3.4 square miles (8.8 square kilometers) in rugged hills of Riverside County. More than 1,300 people were ordered to evacuate their homes Saturday near the community of Aguanga that is home to horse ranches and wineries.
Gusty winds and the chance of thunderstorms into Monday will heighten the risk of renewed growth, the California Department of Forestry and Fire Protection said in a statement.
One firefighter was injured in the blaze, which was 5% contained.
Copyright 2023 The Associated Press. All rights reserved. | https://www.dakotanewsnow.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ | 2023-07-31T05:02:56 | 1 | https://www.dakotanewsnow.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ |
HONG KONG, July 31, 2023 /PRNewswire/ -- Akeso Inc. ("Akeso", the "Company"; 9926.HK), a commercial-stage biopharmaceutical company focused on developing and commercializing first-in-class and best-in-class innovative medicines globally, today announced that it is expected that the Company will record a profit of not less than RMB2.3 billion for the six months ended June 30, 2023. This is the first time for the Company to achieve half-year profits.
The turnaround from loss to profit during the Reporting Period was mainly attributable to:
- In respect of Ivonescimab (AK112, PD-1/VEGF) independently developed by the Company, the Company has entered into the collaborative and licensing agreement with Summit Therapeutics (details of which are set out in the announcement of the Company dated December 6, 2022). The Company has received the total upfront payment equivalent to US$500 million in full during the first quarter of 2023 (details of which are set out in the announcements of the Company dated January 26, 2023 and March 6, 2023). Part of such upfront payment was recognized as licensing fee income which significantly contributed to the revenue of the Company for the Reporting Period, and amounted to approximately RMB2.9 billion. The revenue recognition of the remaining portion of the upfront payment will be recognized as revenue in batches going forward.
- In respect of the Company's innovative product 开坦尼® (cadonilimab, PD-1/CTLA-4), since its launch in June 2022, it has recorded significant increase of the patients as well as product sales, which reflects the excellent clinical value of cadonilimab. In addition, 安尼可®(penpulimab, PD-1) also continued to contribute to the growth in the Company's product sales revenue during the Reporting Period.
- The Company has continued to optimise its cost management capabilities in a scientific and efficient way and has achieved better results in cost control while accelerating innovative products development and pipelines advancement.
About Akeso
Akeso (HKEX: 09926) is a commercial-stage biopharmaceutical company committed to the discovery, development, manufacturing, and commercialization of innovative medicines with high unmet medical needs worldwide. Founded in 2012, the Company has established a comprehensive in-house drug development platform (ACE Platform) and know-how, including R&D, clinical development, CMC (Chemistry, Manufacturing, and Controls), and commercialization capabilities.
With fully integrated multi-functional platform, Akeso is internally working on a robust pipeline of over 30 innovative assets in the fields of cancer, autoimmune disease, inflammation, metabolic disease, and other major therapeutic areas. 19 assets have entered clinical stage. Leveraging in-house developed bispecific platform technology ("Tetrabody technology"), the Company has advanced four potential first-in-class bispecific antibody drugs into market or clinical development, including cadonilimab (PD-1/CTLA-4), ivonescimab (PD-1/VEGF), PD-1/LAG-3, TIGIT/TGF-Beta bispecific antibodies. In June 2022, cadonilimab was approved by the NMPA and became the first commercialized PD-1 based bispecific drug globally. Another Akeso internally discovered and developed oncology product, penpulimab (a PD-1 antibody), was granted marketing approval in China in August 2021. In December 2022, the Company out-licensed breakthrough bispecific antibody, ivonescimab (PD-1/VEGF bi-specific antibody, AK112), with up to US$5 Billion total potential deal value to Summit Therapeutics for development and commercialization in the U.S., Canada, Europe, and Japan.
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SOURCE Akeso, Inc. | https://www.weau.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ | 2023-07-31T05:02:59 | 1 | https://www.weau.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ |
Children learn ins and outs of business in first-ever young entrepreneur fair
Published 9:27 pm Sunday, July 30, 2023
The Albert Lea Farmers Market wasn’t open, but shoppers could still find a variety of items for sale as children ages 6 to 14 were at the North Broadway parking lot Sunday afternoon for the Young Entrepreneurs Business Fair.
The goal: Show children how business worked.
“I know my kids were interested in making and selling products,” said Bri Neely, coordinator for the event. “So I thought why not make a huge event where kids can come do their own things.”
According to Neely, just over a dozen booths were on hand for the fair, and she described the event as a place for kids to display their ideas while making money at the same time.
She hoped the fair inspired participants, taught them about running a business, showed them how to earn money, showed them how to apply creative ideas, developed their imagination and got the community involved.
She also hoped the fair would act as an educational tool, noting not all children wanted to sit at a desk to learn.
“A lot of kids want to go out and do stuff and be involved in the community, and so that was really exciting to watch,” she said. “And just all the parts that go into it: The math, the reading, the writing, all that. It’s been super awesome.”
Of the roughly dozen businesses participating, there was someone selling dog treats, someone selling lemonade; there were jewelry vendors, canvas artists, a boy who sold worms for fishermen, a candle-maker, a girl who ran a nail salon and someone who sold slime.
“Kids love it,” Neely said about the slime.
Planning started back in April, after she got the idea from the Acton Academy.
“A husband and wife started these business fairs probably 10 years ago, and it’s been thriving ever since,” she said. “I got the inspiration from them.”
For her, the biggest challenge was organization and making people aware of the event.
“For a while I was going to quit because I only had [four] people signed up, and it was kind of discouraging … but then my kids were continuing to want to do it and sell their ideas and they were excited when they talked about it,” she said. “From there I changed my mindset and then all of a sudden more people got involved and got excited about it.”
She hadn’t looked back since.
“It’s been really fun,” Neely said. “It’s been fun to see the kids, and they’re just excited to do it. It’s been fun to see people in the community slowly come here to support the kids.”
But the fair was more than an opportunity to make money.
“Just kind of getting that creative gene in these kids and keeping that spark alive on using their creative mind and selling their products,” Neely said.
Colette Wipplinger brought her business — Colette’s Nail Salon — to the fair.
Wipplinger had a history of doing nails in her family, including her sisters’ and those of her mother and grandmother.
“I hope a lot of people come,” she said.
Her mother, Shannon, admitted Colette did good work, and said the idea for the nail salon was Colette’s.
Dustin Cline was among her first customers.
“I think she’s very good at what she does, and I think that a lot of people are saying things about kids not being motivated nowadays,” he said. “Now’s our time to show these kids hard work pays off. Why not [get my nails done].”
London Blake, who has been running Happy Charms since the pandemic, came all the way from the Twin Cities.
“I sell jewelry and croc charms,” she said.
London was there with her mother, Ivory White, who also helped her with the startup.
“She likes to sell,” White said, noting her goal for the event was to network.
Anyone interested in buying from London but who couldn’t attend Sunday’s fair can visit her Facebook page — Happy Charms by London.
According to London, all profits from Sunday’s sales will go toward college.
Cooper Cunningham was operating Cooper’s Garden Co. with his mother, Laura.
“It’s fun,” he said in describing why he wanted to participate.
Marja Stenzel was one of the shoppers Sunday.
“We actually know a couple of the girls that have a booth here, and we wanted to check it out,” she said.
She described the fair as “pretty cool” and thought it was a good way to teach kids about starting and operating a business.
With her was Addie Stenzel.
“I think it’s really cool that a lot of people get to just sell things that they make,” she said, adding that though she wasn’t selling Sunday, she’d consider participating in future fairs and sell bracelets, something she enjoys.
For those who missed it, Neely planned to do more of these fairs in the future, though no dates have been set. For anyone interested in participating in future fairs, visit www.starseedsrevolution.org | https://www.albertleatribune.com/2023/07/children-learn-ins-and-outs-of-business-in-first-ever-young-entrepreneur-fair/ | 2023-07-31T05:03:01 | 1 | https://www.albertleatribune.com/2023/07/children-learn-ins-and-outs-of-business-in-first-ever-young-entrepreneur-fair/ |
For her latest return to series work, Zooey Deschanel is getting “Physical.”
Television’s former “New Girl” joins the cast of Apple TV+’s fitness-themed comedy as it starts its third and final season Wednesday. Her character, Kelly, is an ex-sitcom star who becomes a new threat to Sheila Rubin (returnee Rose Byrne) as the latter continues to grow along with the getting-into-shape business in 1980s San Diego. Sheila has had plenty of challenges along the way already, including building her own identity in the face of her husband’s (Rory Scovel) political aspirations.
Geoffrey Arend, Paul Sparks, Deirdre Friel and Lou Taylor Pucci also continue their roles in the Annie Weisman-created show’s final round, which Deschanel was pleased to sport a different look for – going blond for her role.
“It was so much fun,” the actress confirms. “The hair, makeup and costume team on that show was absolutely amazing, … and she’s a complex character, very multifaceted. I kind of got to play two different versions of the character that made sense within one character, so that was cool. It’s really clever storytelling.”
Deschanel also appreciated working with Byrne: “I love Rose. She’s a really kind person, very easy to work with … and so generous. She has no ego or vanity; she’s just a good actress who’s really lovely. I can’t say enough good things about her.”
Though she went into “Physical” knowing her role would last only so long, due to it being the last season, Deschanel says, “I would have been happy to come back if it was going for more seasons, but I like that the character has a beginning, middle and end.
“I get to play it all out, as opposed to when you’re on a show and you’re unsure of whether it’s ending or not. We had a number of seasons like that on ‘New Girl,’ so it was nice to know ahead of time what I would be leaving people with. I could really be intentional about all of that.”
Being able to concentrate just on acting without other responsibilities on “Physical” also was pleasant for Deschanel, though she admits, “It’s hard for me to take off my ‘producer’ hat. I want everything to be efficient and make sense from a production standpoint, so I always bring that with me.
“I always think that if you’re on a set, you’re a filmmaker, even if you have different jobs. You need to make sure you’re collaborating in a way that everyone is helping you do your best, so knowing about all the other jobs like camera and sound is really important, I think.”
The sister of fellow actress Emily Deschanel (“Bones”), Zooey is quite visible these days, also in her Max culinary reality series “What Am I Eating?” and commercials that cast her as a “Fairy Hotel Mother” who soothes travelers.
“All the stuff I did over time has all come out,” she says. “When ‘New Girl’ ended, I took some time off to be with my kids, because that was such a massive and all-encompassing project. (Deschanel was also an executive producer.) Then there was the pandemic year, and then I just went right back to work and did a bunch of stuff.” | https://www.journalgazette.net/living/entertainment/tv/physical-evidence-zooey-deschanel-joins-apple-tv-series-for-final-season/article_04b756e2-2c8a-11ee-b1c0-6b92281183d9.html | 2023-07-31T05:03:02 | 1 | https://www.journalgazette.net/living/entertainment/tv/physical-evidence-zooey-deschanel-joins-apple-tv-series-for-final-season/article_04b756e2-2c8a-11ee-b1c0-6b92281183d9.html |
Six migrant workers were struck Sunday afternoon by an SUV in a Walmart parking lot in North Carolina from what police are calling "an intentional assault with a vehicle."
"All six were transported to Atrium Health – Lincoln with various injuries. None of the injuries appear to be life threatening," the Lincolnton Police Department said in a Facebook post.
Police say they're still looking for the vehicle and driver involved in the incident, which they said took place at 1:17 pm ET. In the Facebook post, they describe the vehicle as an older model SUV with a luggage rack, and the driver as an older white male.
The motive for the attack is also still under investigation. Police told NPR via telephone late Sunday there is no further information.
Lincolnton is a small city of some 11,800 people located about an hour outside of Charlotte.
Copyright 2023 NPR. To see more, visit https://www.npr.org. | https://www.ijpr.org/npr-news/2023-07-30/an-suv-strikes-6-migrant-workers-in-walmart-parking-lot-in-north-carolina | 2023-07-31T05:03:02 | 0 | https://www.ijpr.org/npr-news/2023-07-30/an-suv-strikes-6-migrant-workers-in-walmart-parking-lot-in-north-carolina |
Four winners wrap up month of July at I-90 Speedway
Saturday night feature race highlights
HARTFORD, S.D. (Dakota News Now) - Ryan Bickett scored the first Spielman Excavating IMCA Sprint Car victory of his career Saturday night at I-90 Speedway – but his 21st overall win at the track. Meantime, Cory Yeigh won in the First Interstate Bank Late Model Street Stocks, Duke Erickson got his first track win in the Reaves Buildings USRA B-Mods and Nick Brady was victorious in the USRA Hobby Stocks.
Bickett showed the way for all 20 laps of the sprint car feature, but it was close in the final laps as Lee Goos Jr. and John Lambertz challenged for the lead as they all raced through traffic. At the checkered, twelfth starting Goos was second with ninth starting Lambertz in third. Tyler Rabenberg raced from eleventh to take fourth just ahead of Koby Werkmeister.
Yeigh was the third different leader in the late model street stock feature and at the checkered it marked his fourth win of the year and career win 39 at the track – win number 26 in the class putting him in a tie for sixth most in the class history. JJ Zebell was second with Matt Steuerwald in third. Tracy Halouska and Colby Klaassen completed the top five.
Duke Erickson took the lead on the final lap of B-mod feature to score the first win of his career at I-90 Speedway. Dustin Johnson took over the lead on lap two and held it until the final lap then placed second. Derek VanVeldhuizen was third with Camden Myers in fourth and Dustin Kruse in fifth.
Nick Brady raced to the lead on lap ten of the hobby stock feature from the eleventh starting position. Brady would go from there to his second win of the season and fifteenth of his career. Tracy Halouska followed from twelfth to second. Landon Krohn was third from tenth with Josh Downs (filling in for Angela Downs) taking fourth with Jason Bradley in fifth.
I-90 Speedway is back in action this Saturday night with a full night of action with the RPM Race Series. The hobby stocks will also have their special King of the Hill event.
Copyright 2023 KSFY. All rights reserved. | https://www.dakotanewsnow.com/2023/07/31/four-winners-wrap-up-month-july-i-90-speedway/ | 2023-07-31T05:03:03 | 0 | https://www.dakotanewsnow.com/2023/07/31/four-winners-wrap-up-month-july-i-90-speedway/ |
CHENGDU, China, July 30, 2023 /PRNewswire/ -- On July 29, in the Men's Nanquan of Wushu tournament, China's athlete Cao Maoyuan won the first gold medal at the 31st FISU World University Games with a score of 9.770.
Cao Maoyuan stood on the podium, showcasing his glory to the world. The medal around his neck, accompanied by a radiant medal ribbon, caught everyone's attention. But what makes this seemingly ordinary medal ribbon so remarkable? It's the embodiment of Chengdu's cultural charm. According to Hu Guangjun, the director of the Chengdu Shu Brocade Research Institute, the medal ribbon for this edition of the Games has ingeniously incorporated the millennia-old weaving techniques of Shu brocade. Adorned with iconic symbols of Chengdu's historical and cultural significance, such as hibiscus flowers and sun birds, the ribbon exudes a captivating luster. This transforms China's intangible cultural heritage into a tangible "Rongguang" (the brilliance of Chengdu) that can be truly appreciated.
Shu brocade weaving skills are China's national intangible cultural heritage. Dating back to the Han Dynasty, Shu brocade has been a vital "protagonist" in trade along the Silk Road, earning its place as a cultural emblem of Chengdu and a symbol of cultural exchange between the East and West. With the unveiling of the first medal of the Games, Chengdu proudly showcases this cherished cultural business card to the world once again.
This outstanding cultural business card was produced in the workshop of Chengdu Shu Brocade Research Institute in Shuangliu District. According to Hu Guangjun, the location of the Chengdu Shu Brocade Research Institute in Shuangliu stems from its long history of silk culture. During the Three Kingdoms period, renowned strategist Zhuge Liang resided in Gemo Village, Shuangliu, where he emphasized the significance of Shu brocade by stating, "In the current circumstances of impoverishment and an empty treasury, we rely solely on Shu brocade for the necessary materials to confront our enemies." This highlights the historical importance of Shu brocade at that time. Moreover, a piece of Shu brocade known as "Lianzhu Loong Pattern Brocade" was excavated from the 226th tomb of Astana in Turpan, Xinjiang in the last century. The relic clearly records its origin in Shuangliu, bearing witness to the flourishing and prosperous Shu brocade industry in the Shuangliu region during the Tang Dynasty.
To infuse traditional Shu brocade with a fashionable touch, Hu Guangjun collaborated with a design team composed of Ma Liwa, a teacher, and students from the College of Chinese & ASEAN Arts at Chengdu University. Together, they tirelessly refined and revised the design, from pattern creation to machine production. This meticulous process took nearly six months to complete. Moreover, the transformation of mulberry silk into the medal ribbons required over 70 intricate steps.
Apart from the medal ribbons, the Chengdu Shu Brocade Research Institute has introduced a range of Games-related merchandise crafted from Shu brocade fabrics, including mirrors and bucket hats. These products seamlessly blend traditional culture with contemporary fashion elements, showcasing the progressive charm of Shu brocade. As a result, they have captured the attention of many young individuals who are now eager to explore and appreciate the beauty of Shu brocade.
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Link: https://iop.asianetnews.net/view-attachment?attach-id=441679
Caption: Medal Ribbon of Chengdu FISU Games
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SOURCE The Chengdu Shu Brocade Research Institute | https://www.weau.com/prnewswire/2023/07/31/chengdu-fisu-games-first-gold-medal-awarded-medal-ribbon-showcasing-chengdus-cultural-essence/ | 2023-07-31T05:03:05 | 0 | https://www.weau.com/prnewswire/2023/07/31/chengdu-fisu-games-first-gold-medal-awarded-medal-ribbon-showcasing-chengdus-cultural-essence/ |
Trust and culture help Harrisburg capture first State Legion Championship
Post 45 will face Minnesota State Champion St. Michael in Central Plains Regional in Rapid City on Wednesday
YANKTON, S.D. (Dakota News Now) - The growth in Harrisburg and the numbers within their legion baseball program forced them to field two teams this season for the first time.
The development of Post 45′s program was shown yesterday when they won their first ever State A Legion Championship.
And its hard to imagine a better way to make history than the way they did, with their “Gold” squad coming from behind to beat Brookings 3-2 in the championship game on Coen Cook’s walkoff single in the bottom of the 7th.
Harrisburg has had plenty of great teams before, most recently in 2021 when they featured Division One athletes Will Simmons and Chase Mason. Though significantly younger than that group, the culture that has been built up in Harrisburg over the years made this the team to finally put the program over the top.
Post 45 has a quick turnaround after yesterday’s win as they head to the Central Plains Regional which starts on Wednesday in Rapid City. They’ll face Minnesota State Legion champion St. Michael at 4:00 PM.
Copyright 2023 KSFY. All rights reserved. | https://www.dakotanewsnow.com/2023/07/31/trust-culture-help-harrisburg-capture-first-state-legion-championship/ | 2023-07-31T05:03:09 | 1 | https://www.dakotanewsnow.com/2023/07/31/trust-culture-help-harrisburg-capture-first-state-legion-championship/ |
SEATTLE, July 30, 2023 /PRNewswire/ -- Monport Laser has been at the forefront of laser engraving innovation, spearheading the development of cutting-edge laser engravers and cutters. Building upon its world-leading expertise in the laser engraving industry, the company is now ready to captivate the market with its latest breakthroughs. In August, Monport Laser is scheduled to announce a range of new laser engraving machines, specifically engineered to handle various materials.
After six months of relentless effort from Monport's development technical team, their eagerly anticipated product will finally be revealed to all laser creators in early August of this year. The development of this innovative machine began with thousands of customer survey questionnaires for laser marking machines, rigorous testing, and product designer assessments. Engineers conducted over a dozen rounds of machine sample screening and in the final design stage, they took the unusual step of bringing in external senior personnel and engraving novices to carry out engraving tests for an entire month. This dedication to improvement and openness to feedback ensures a professional and user-friendly final fiber laser.
Monport GP Fiber Laser Series is not only Lightweight but Compact
Laser engraving machines have long faced difficulties when it comes to laser focusing, causing technical support headaches. Monport's latest innovation in marking machine can answer all these troubles. The new product boasts an electric and manual double lifting focus method, designed to make laser focusing seamless and improve the final engraving result. With this cutting-edge technology, users can operate without any barriers, and achieve the perfect, professional engraving effect.The electric lifting focus is suitable for beginners while the manual focus is the best for experienced users. This new integrated fiber laser is truly versatile in achieving any special engraving effects needed.
Breaking away from the conventional split type designs flooding the market, Monport introduces a game-changing one-piece design for their latest marking machine. This ingenious development not only saves valuable space but also ensures portability becomes a breeze. Bella, a senior developer at Monport Laser, proudly declared, "Our exceptional team of female developers has personally experienced the convenience of this machine. They effortlessly moved it from one studio to another, adjusting the base's height for easy handling right off the table. The commitment to a user-friendly experience is not just a mere claim."
In striking comparison to other conventional 33kg machines, Monport GP Series Fiber Series introduces their groundbreaking 20-22 kg all-in-one machine, setting a new industry standard for its exceptional lightness. The machine boasts rounded leading corners, diligently crafted to prevent unwanted bumps and damage during handling and transportation. Monport's thoughtful consideration extends further with the addition of a dustproof board, ensuring optimal performance and longevity. Endowed with an exceptional user-friendly experience and multifunctional capabilities, this machine embodies Monport Laser's unwavering dedication to continuous upgrades, always keeping the user at the forefront.
Monport GI Series MOPA Lasers Redefine Color Fast Marking
Monport's exciting product launch not only includes the highly anticipated new additions to the GP Series but also showcases the cutting-edge GI Series color engraving fiber machine. This JPT MOPA fiber laser is built to last, offering precision, durability, and longevity that surpasses expectations. With its remarkable laser cutting capability, it can effortlessly cut up to 0.05 mm with each pass, achieving an astonishing accuracy of ±0.1 microns.
Extensive Support and Remarkable Fiber Accessories
Complementing the multitude of advantages offered by their cutting-edge machine, Monport Laser goes above and beyond by providing customers with comprehensive support and unparalleled expandability. The new fiber series from Monport introduces a range of accessories designed to elevate the engraving experience. One notable addition is the safety shells, embedded with radiation protection and noise reduction functions, creating a secure and tranquil environment for users.
As a testament to their commitment to customer satisfaction, Monport Laser also includes 10 different test materials, ranging from metal rings to key chains and cards made from various metal materials, enabling users to explore and experiment with ease.
By empowering businesses and industries, expanding the creative landscape for maker spaces, unleashing innovation, and creating opportunities for growth, Monport Laser is at the forefront of revolutionizing the laser engraving field.
Company: Monport Laser
Contact email: official@monportlaser.com
Pre-sales Phone: (+1)332-251-1208
Monport Laser Website: https://monportlaser.com/
Monport Adress: Monport Tech Inc. 300 LENORA ST 878, SEATTLE, WA, 98121-2411, UNITED STATES
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SOURCE Monport Laser | https://www.weau.com/prnewswire/2023/07/31/monport-laser-unveils-new-gp-series-gi-series-fiber-lasers-redefine-precision-performance/ | 2023-07-31T05:03:12 | 0 | https://www.weau.com/prnewswire/2023/07/31/monport-laser-unveils-new-gp-series-gi-series-fiber-lasers-redefine-precision-performance/ |
Tucker Kraft settling in with Packers
Timber Lake native and SDSU alum in first NFL Training Camp
GREEN BAY, WI (Dakota News Now) - A year ago Tucker Kraft was heading into fall camp at South Dakota State as one of the top NFL Draft prospects in the FCS.
A National Championship and third round selection by the Green Bay Packers later and it’s time for the Timber Lake native to prove he can fulfill that potential.
As training camp got underway this past week in Green Bay the same can of course be said for a lot of the Packers offense with Jordan Love finally getting a chance to start at quarterback and Tucker facing competition at his own tight end position from fellow rookie and second round pick Luke Musgrave.
After offseason OTA’s and workouts with the Packers Tucker isn’t starting from scratch, and each practice at training camp gives him a chance to drill down and fine tune.
You can see Tucker make his Packers preseason debut on the Dakota News Now Family of Networks. Packers games will be carried on KDLT and the CW starting August 11th at Cincinnati.
Copyright 2023 KSFY. All rights reserved. | https://www.dakotanewsnow.com/2023/07/31/tucker-kraft-settling-with-packers/ | 2023-07-31T05:03:15 | 1 | https://www.dakotanewsnow.com/2023/07/31/tucker-kraft-settling-with-packers/ |
NANJING, China, July 31, 2023 /PRNewswire/ -- Nanjing Leads Biolabs Co., Ltd. (hereinafter referred to as "Leads Biolabs" or "Company") announced today that the National Medical Products Administration (NMPA) and the U.S. Food and Drug Administration (FDA) have approved its first-in-human Investigational New Drug (IND) applications for LBL-034, an anti-GPRC5D/CD3 bispecific antibody invented by Leads Biolabs with global intellectual property rights, for the treatment of relapsed/refractory multiple myeloma. Currently, no GPRC5D-targeting antibody has been approved for marketing.
This is a first-in-human, single-arm, multicenter, open-label, dose-escalation and expansion clinical study, and plans to enroll patients with relapsed/refractory multiple myeloma who have failed prior therapies including but not limited to at least one proteasome inhibitor (PI), one immunomodulator (IMiD) as well as other standard treatments. This study aims to evaluate the safety and tolerability of LBL-034, determine the recommended Phase II dose and assess its efficacy in patients with multiple myeloma.
"Despite recent progress and continuous advancements in multiple myeloma, the time between recurrences has been steadily decreasing, particularly as the number of treatment lines increases. This ultimately leads to emergence of relapsed or refractory multiple myeloma, reaffirming its status as an incurable malignant tumor that poses a serious threat to human life. In light of this challenging reality, the urgent need for more effective and innovative treatment options has never been more evident." said Dr. Charles Cai, Chief Medical Officer of Leads Biolabs, "LBL-034 adopts a unique molecular design, which enables the drug to specifically bind to GPRC5D-expressing tumor cells with high affinity, and reduces the risk of non-specific activation of T-cells, thereby enhancing anti-tumor efficacy and reducing potential risk of immunotoxicity. LBL-034 demonstrated robust anti-tumor activities and good safety profile in pre-clinical studies. We adhere to our tradition of innovation and aim to deliver an important, novel and effective treatment option for patients with poor prognosis of relapsed/refractory multiple myeloma."
About GPRC5D:
G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D) is a C-type 7-channel transmembrane receptor protein. GPRC5D is low expressed in normal human tissues but specifically overexpressed in multiple myeloma. The intensity of GPRC5D expression is an independent prognostic factor in multiple myeloma, and its overexpression is significantly associated with reduced overall survival. Therefore, GPRC5D may be an important potential target for the treatment of plasma cell diseases such as multiple myeloma.
About multiple myeloma:
Multiple myeloma is a malignant plasma cell disease caused by abnormal proliferation of clonal plasma cells, accounting for 10-15% of hematologic malignancies and about 1.4% of all malignancies. It is the second most common hematological malignancy in adults after non-Hodgkin's lymphoma and mostly occurs in the elderly. According to the data released by the World Health Organization (WHO), the number of new cases and deaths of multiple myeloma worldwide in 2020 were 176,000 and 117,000 respectively, and the number of new cases and deaths of multiple myeloma in China were 21,000 and 16,000 respectively. Currently, multiple myeloma is still an incurable malignant tumor, and the five-year survival rate of patients is approximately 24.8% in China, 33.3% in Japan, and 46.7% in the United States. In recent years, with the successful development of proteasome inhibitors (PIs), immunomodulatory drugs (IMiDs), selective nuclear output inhibitors, CD38-targeted antibodies, bispecific antibodies, and CAR-T cell therapies, the tumor response rate and survival prognosis have been significantly improved. However, multiple myeloma remains an unmet clinical need for more effective treatments.
About LBL-034:
LBL-034 is a humanized IgG1 subtype asymmetric bispecific antibody targeting both GPRC5D and CD3 and Leads Biolabs fully owns the worldwide intellectual property rights. LBL-034 induces T-cell-mediated killing of myeloma cells by redirecting CD3+ T-cells to myeloma cells expressing GPRC5D.
LBL-034 has the potential to be a transformative best-in-class GPRC5D-targeted immunotherapy for multiple myeloma. Clinical studies are planned to evaluate the safety and efficacy of LBL-034 in patients with relapsed/refractory multiple myeloma.
Nanjing Leads Biolabs Co., Ltd. is a clinical-stage biotechnology company founded in Nanjing by a team of senior U.S.-trained antibody drug developers. Since 2014, Leads Biolabs has been dedicated to the discovery and development of novel antibody drugs with independent intellectual property rights for the treatment of oncology and other major diseases of high unmet medical needs, particularly the challenges in cancer immunotherapy. Our extensive R&D pipeline consist of more than twenty novel tumor immunotherapy molecules based on monoclonal and bispecific antibody technology platforms. Leads Biolabs is committed to providing safe, effective, accessible and affordable new drugs to address the unmet needs of patients around the world.
For more information, please visit: https://www.leadsbiolabs.com
Business contact: bd@leadsbiolabs.com
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SOURCE LEADS BIOLABS | https://www.weau.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ | 2023-07-31T05:03:19 | 1 | https://www.weau.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ |
Classes
“W IS FOR WATER”: Salamonie Lake’s Preschool offers preschool-age children and their adults an opportunity to learn why water so important to Salamonie Lake at Upper Wabash Interpretive Services, 3691 S. New Holland Road, Andrews. The class, for children ages 2 to 5, will be 10 to 11:30 a.m. Aug. 17. Each program is designed to enhance the preschooler’s basic education, including music, crafts, social interaction and always with a nature-related theme. The fee is $2 per child. Advance registration is requested. Register by calling Upper Wabash Interpretive Services at 260-468-2127.
Events
MAKING STRIDES AGAINST BREAST CANCER: The American Cancer Society is kicking off the 26th annual Making Strides Against Breast Cancer season in Fort Wayne. Event organizers will host a celebration on from 5 to 7 p.m. Aug. 8 at Quimby Hall, 1502 Bluffton Road. The walk is held each October and provides a supportive community for courageous breast cancer survivors and metastatic breast cancer thrivers, caregivers and families alike. Making Strides Against Breast Cancer of Fort Wayne has a fundraising goal of $150,000 this year.
ANTIQUE APPRAISAL EVENT: Adams Woodcrest will host an Antique Appraisal Event with Timothy McCulloch of Scheerer McCulloch Real Estate from 2 to 4 p.m. Aug. 10 in the Porter Auditorium in Decatur. The Scheerer McCulloch company has requested a two-item limit per person/family. Community guests and Adams Woodcrest residents are asked to RSVP by Aug. 4 and indicate the items they plan to bring. Contact Adams Woodcrest at 260-724-3311 or email Amy Hake at amy.hake@adamshealthnetwork.org. Snacks and refreshments will be served.
SUMMER SIDEWALK SALES: Downtown Wabash Inc. will host its annual Summer Sidewalk Sales event in conjunction with the 24th Annual Dave Kunkel Cruise-In and the Downtown Wabash Farmers Market at Paradise Spring Park. The Kunkel Cruise-In will bring in more than 400 classic cars at the Honeywell Center. The weekend festivities will be Aug. 18 and 19 with free rides on Trolley No. 85 throughout downtown Wabash for easy transportation between all three events. Hours for the sidewalk sales vary by retailer. The Downtown Wabash Farmers Market at Paradise Spring Park will be 8 a.m. to noon on Aug. 19. The cruise-in will be 3 to 9 p.m. Aug. 18 and 9 a.m. to 3 p.m. Aug. 19. Funds raised at the event will go toward ALS research in honor of Dave Kunkel, a native of Wabash County.
Fundraisers
FISH FRY: Ft. Wayne Maennerchor/Damenchor will host fish fry events, all-you-can eat, in upcoming months at Park Edelweiss, 3355 Elmhurst Drive. Fish Fry dates are Aug. 11, Sept. 8, Oct. 13 and Nov. 3. The time is 4:30 to 7 p.m. Cost is $12 for adults; $6 for children. Full-service bar will be available with German and domestic beer, wine and other beverages and soft drinks. Carry out is available. For more information, contact Patti Knox at 260-444-3634.
HEALTHVISIONS MIDWEST OF FORT WAYNE: The 25th annual celebration and fundraiser will be Sept. 29. The featured speaker will be Anushay Hossain, a Washington, D.C.-based author and policy analyst who wrote “The Pain Gap: How Sexism and Racism in Healthcare Kill Women.” Ticket cost, which includes breakfast, is $50 for the event from 8 to 10 a.m. at the Grand Wayne Center. HealthVisions will also announce the 2023 Dignity Award recipients. Nominations are due Aug. 11. For the event registration or sponsorship details, go online at hvusa.org/rethinkinghealth or contact Felicia Say at 260-745-1600.
Health
ART SUPPORT GROUP: The Indiana Arts Commission announced its award of $4,000 to Mental Health America of Northeast Indiana for its Peer-Led Art Support Group through the Arts Project Support grant program. The local nonprofit will use the funds to provide peer support through its new Art Support Group. Research shows that peer support is vital to mental wellness, especially for recovery and maintenance. The Art Support Group will be led by a facilitator who understands the difficulty of navigating intense emotions. The group will be free to anyone aged 13 and older interested in art and its intersection with mental health. Beginning Sept. 12, meetings will take place every second and fourth Tuesday of the month from 6 to 7 pm at Studi07, 3414 Fairfield Ave. Learn more at https://mhanortheastindiana.org/.
Library
INDIANA AUTHORS AWARDS: The Eugene and Marilyn Glick Indiana Authors Awards will be in Fort Wayne Aug. 31 with Hoosier author Kekla Magoon. A Fort Wayne native, Magoon has written several books, including “The Season of Styx Malone,” “The Rock and the River” and “Revolution in Our Time: The Black Panther Party’s Promise to the People” and received numerous awards. The Aug. 31 presentation is at the Allen County Public Library, 900 Library Plaza, Fort Wayne. Doors open at 5:30 p.m. Tickets: https://keklamagoonfortwayne.eventbrite.com
STORY TIME and FAMILY TIME: Dinosaurs is the theme for the LaGrange County Public Library System for story time for children up to age 5. It will be held in August at 10:30 a.m. Tuesdays at the LaGrange County library; 1 p.m. Tuesdays at the Shipshewana Branch; and 11 a.m. Wednesdays at the Topeka Branch. Other programming for August includes Classic Cinema: Family Time at 2 p.m. Tuesdays in August, which includes free moves and popcorn and is recommended for viewers age 12 and older. More details about library system’s programming is online at www.lagrange.lib.in.us
Seniors
SENIOR MONDAY LUNCHEON: Upper Wabash Interpretive Services will host a lunch and lecture at noon, Aug. 7 at the Salamonie Lake Interpretive Center, 3691 New Holland Road, Andrews. Anyone age 50 or older is welcome to attend. Butch Williams, former deputy director of HCEMA/Homeland Security, will present severe weather safety tips and ways to receive severe weather information. The talk will be geared toward those who are outdoors, including fishermen, hikers and bikers. The carry-in meal begins at noon. Guests should bring a side dish to share, a beverage and their own table service. The main dish of Salisbury steak is provided. A donation will be accepted to help defray costs. Seating is limited. Reservations may be made by calling 260-468-2127.
If you have information you would like considered for Community Update, please submit it at least two weeks before the desired publication date to community@jg.net. All submissions must be via email. | https://www.journalgazette.net/local/community-update-a-calendar-of-area-classes-fundraisers-and-events/article_ed0a388a-274c-11ee-aefb-9fffd00099f5.html | 2023-07-31T05:03:20 | 1 | https://www.journalgazette.net/local/community-update-a-calendar-of-area-classes-fundraisers-and-events/article_ed0a388a-274c-11ee-aefb-9fffd00099f5.html |
HONG KONG, July 31, 2023 /PRNewswire/ -- Akeso Inc. ("Akeso", the "Company"; 9926.HK), a commercial-stage biopharmaceutical company focused on developing and commercializing first-in-class and best-in-class innovative medicines globally, today announced that it is expected that the Company will record a profit of not less than RMB2.3 billion for the six months ended June 30, 2023. This is the first time for the Company to achieve half-year profits.
The turnaround from loss to profit during the Reporting Period was mainly attributable to:
- In respect of Ivonescimab (AK112, PD-1/VEGF) independently developed by the Company, the Company has entered into the collaborative and licensing agreement with Summit Therapeutics (details of which are set out in the announcement of the Company dated December 6, 2022). The Company has received the total upfront payment equivalent to US$500 million in full during the first quarter of 2023 (details of which are set out in the announcements of the Company dated January 26, 2023 and March 6, 2023). Part of such upfront payment was recognized as licensing fee income which significantly contributed to the revenue of the Company for the Reporting Period, and amounted to approximately RMB2.9 billion. The revenue recognition of the remaining portion of the upfront payment will be recognized as revenue in batches going forward.
- In respect of the Company's innovative product 开坦尼® (cadonilimab, PD-1/CTLA-4), since its launch in June 2022, it has recorded significant increase of the patients as well as product sales, which reflects the excellent clinical value of cadonilimab. In addition, 安尼可®(penpulimab, PD-1) also continued to contribute to the growth in the Company's product sales revenue during the Reporting Period.
- The Company has continued to optimise its cost management capabilities in a scientific and efficient way and has achieved better results in cost control while accelerating innovative products development and pipelines advancement.
About Akeso
Akeso (HKEX: 09926) is a commercial-stage biopharmaceutical company committed to the discovery, development, manufacturing, and commercialization of innovative medicines with high unmet medical needs worldwide. Founded in 2012, the Company has established a comprehensive in-house drug development platform (ACE Platform) and know-how, including R&D, clinical development, CMC (Chemistry, Manufacturing, and Controls), and commercialization capabilities.
With fully integrated multi-functional platform, Akeso is internally working on a robust pipeline of over 30 innovative assets in the fields of cancer, autoimmune disease, inflammation, metabolic disease, and other major therapeutic areas. 19 assets have entered clinical stage. Leveraging in-house developed bispecific platform technology ("Tetrabody technology"), the Company has advanced four potential first-in-class bispecific antibody drugs into market or clinical development, including cadonilimab (PD-1/CTLA-4), ivonescimab (PD-1/VEGF), PD-1/LAG-3, TIGIT/TGF-Beta bispecific antibodies. In June 2022, cadonilimab was approved by the NMPA and became the first commercialized PD-1 based bispecific drug globally. Another Akeso internally discovered and developed oncology product, penpulimab (a PD-1 antibody), was granted marketing approval in China in August 2021. In December 2022, the Company out-licensed breakthrough bispecific antibody, ivonescimab (PD-1/VEGF bi-specific antibody, AK112), with up to US$5 Billion total potential deal value to Summit Therapeutics for development and commercialization in the U.S., Canada, Europe, and Japan.
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SOURCE Akeso, Inc. | https://www.dakotanewsnow.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ | 2023-07-31T05:03:21 | 1 | https://www.dakotanewsnow.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ |
SEATTLE, July 30, 2023 /PRNewswire/ -- Monport Laser has been at the forefront of laser engraving innovation, spearheading the development of cutting-edge laser engravers and cutters. Building upon its world-leading expertise in the laser engraving industry, the company is now ready to captivate the market with its latest breakthroughs. In August, Monport Laser is scheduled to announce a range of new laser engraving machines, specifically engineered to handle various materials.
After six months of relentless effort from Monport's development technical team, their eagerly anticipated product will finally be revealed to all laser creators in early August of this year. The development of this innovative machine began with thousands of customer survey questionnaires for laser marking machines, rigorous testing, and product designer assessments. Engineers conducted over a dozen rounds of machine sample screening and in the final design stage, they took the unusual step of bringing in external senior personnel and engraving novices to carry out engraving tests for an entire month. This dedication to improvement and openness to feedback ensures a professional and user-friendly final fiber laser.
Monport GP Fiber Laser Series is not only Lightweight but Compact
Laser engraving machines have long faced difficulties when it comes to laser focusing, causing technical support headaches. Monport's latest innovation in marking machine can answer all these troubles. The new product boasts an electric and manual double lifting focus method, designed to make laser focusing seamless and improve the final engraving result. With this cutting-edge technology, users can operate without any barriers, and achieve the perfect, professional engraving effect.The electric lifting focus is suitable for beginners while the manual focus is the best for experienced users. This new integrated fiber laser is truly versatile in achieving any special engraving effects needed.
Breaking away from the conventional split type designs flooding the market, Monport introduces a game-changing one-piece design for their latest marking machine. This ingenious development not only saves valuable space but also ensures portability becomes a breeze. Bella, a senior developer at Monport Laser, proudly declared, "Our exceptional team of female developers has personally experienced the convenience of this machine. They effortlessly moved it from one studio to another, adjusting the base's height for easy handling right off the table. The commitment to a user-friendly experience is not just a mere claim."
In striking comparison to other conventional 33kg machines, Monport GP Series Fiber Series introduces their groundbreaking 20-22 kg all-in-one machine, setting a new industry standard for its exceptional lightness. The machine boasts rounded leading corners, diligently crafted to prevent unwanted bumps and damage during handling and transportation. Monport's thoughtful consideration extends further with the addition of a dustproof board, ensuring optimal performance and longevity. Endowed with an exceptional user-friendly experience and multifunctional capabilities, this machine embodies Monport Laser's unwavering dedication to continuous upgrades, always keeping the user at the forefront.
Monport GI Series MOPA Lasers Redefine Color Fast Marking
Monport's exciting product launch not only includes the highly anticipated new additions to the GP Series but also showcases the cutting-edge GI Series color engraving fiber machine. This JPT MOPA fiber laser is built to last, offering precision, durability, and longevity that surpasses expectations. With its remarkable laser cutting capability, it can effortlessly cut up to 0.05 mm with each pass, achieving an astonishing accuracy of ±0.1 microns.
Extensive Support and Remarkable Fiber Accessories
Complementing the multitude of advantages offered by their cutting-edge machine, Monport Laser goes above and beyond by providing customers with comprehensive support and unparalleled expandability. The new fiber series from Monport introduces a range of accessories designed to elevate the engraving experience. One notable addition is the safety shells, embedded with radiation protection and noise reduction functions, creating a secure and tranquil environment for users.
As a testament to their commitment to customer satisfaction, Monport Laser also includes 10 different test materials, ranging from metal rings to key chains and cards made from various metal materials, enabling users to explore and experiment with ease.
By empowering businesses and industries, expanding the creative landscape for maker spaces, unleashing innovation, and creating opportunities for growth, Monport Laser is at the forefront of revolutionizing the laser engraving field.
Company: Monport Laser
Contact email: official@monportlaser.com
Pre-sales Phone: (+1)332-251-1208
Monport Laser Website: https://monportlaser.com/
Monport Adress: Monport Tech Inc. 300 LENORA ST 878, SEATTLE, WA, 98121-2411, UNITED STATES
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SOURCE Monport Laser | https://www.dakotanewsnow.com/prnewswire/2023/07/31/monport-laser-unveils-new-gp-series-gi-series-fiber-lasers-redefine-precision-performance/ | 2023-07-31T05:03:24 | 1 | https://www.dakotanewsnow.com/prnewswire/2023/07/31/monport-laser-unveils-new-gp-series-gi-series-fiber-lasers-redefine-precision-performance/ |
Partnership adds cryptocurrency as a payment option for merchants using Optty's universal payment platform
SINGAPORE, July 30, 2023 /PRNewswire/ -- Optty, the world's first universal payments platform, today announced a new partnership with Triple-A, a licensed crypto payment gateway, to add cryptocurrency as a payment option on the platform. As the central hub connecting and streamlining a robust global network of Buy Now Pay Later (BNPL) providers, this milestone marks the launch of Optty's sixth payment architecture, further expanding viable payment options for merchants and convenience for their end customers.
Sign-up and integration with Optty is free. To get started, please visit: https://www.optty.com/merchant-account
"As the world's first true universal payments platform, Optty is agnostic and supportive of payments inclusion, a unique position that is designed to help retailers offer more choice than ever at checkout," said Natasha Zurnamer, CEO and founder of Optty. "With one simplified integration, not only can retailers access over 90 BNPLs and local payment methods in over 120 countries — they can now switch on crypto payments, a natural progression in our aim to simplify payments for retailers all over the world."
The first crypto payment gateway to be licensed by the Monetary Authority of Singapore, Triple-A is also licensed in Europe, through Banque de France's ACPR, and registered with the United States Financial Crimes Enforcement Network (FinCEN). Through the collaboration with Triple-A's white label crypto payment gateway, Optty enables retailers and merchants to offer a wide range of payment methods. This allows them to test and learn which payment types best resonate with their customers.
Tapping into diverse consumer payment preferences
With Optty's vast global network of gateways that license the company's unique payment stacks, merchants and retailers can now leverage Triple-A's gateway to accept cryptocurrencies such as Bitcoin (BTC), Ethereum (ETH), Tether (USDT), and USD Coin (USDC). Triple-A's crypto payment gateway is compatible with all crypto wallets, allowing customers to make hassle-free payments using their preferred wallet.
Through real-time crypto-to-fiat conversions facilitated by Triple-A, retailers can receive payments in cryptocurrencies without the need to manage them on their balance sheets and constantly monitor fluctuating exchange rates. Retailers enjoy next-day local currency bank settlements in 50+ currencies, enabling quick access to funds in their preferred currency. Additionally, businesses have the option to offer their customers the convenience of paying through Binance Pay.
Optty already offers Buy Now Pay Later, Debit and Credit, Digital Wallets, Peer to Peer payments, and bank transfer options, and the addition of crypto enables merchants to tap into the spending power of 420 million crypto owners worldwide. Optty plans to further expand payment architectures to a total of nine by the end of 2023.
"We are excited to partner with Optty and bring crypto payments to their merchants," said Eric Barbier, CEO of Triple-A. "This collaboration will help merchants take advantage of the growing demand for cryptocurrency payments, without the hassle of managing crypto assets on their balance sheets."
Disruption through simplification
Previously, retailers and merchants would need to spend a great deal of time and money on complex, one-by-one payment integration processes. Optty changed all this by eliminating it, revolutionizing the way merchants access payments methods globally. Available across ecommerce, IVR, and in-store, it is a true PaaS that offers retailers a simplified integration while providing a seamless and direct commercial partnership channel, enabling an application process with every payment provider in the solution.
About Optty
As a PaaS, Optty is the world's first true universal payments platform that integrates over 90 installment (BNPL) brands — more than any other existing single integration solution globally — and offers six payment architectures, soon to be nine by the end of 2023. Its payments-, partner- and channel-agnostic approach delivers wide payments connectivity globally to schemes, acquirers, gateways and retailers alike and offers a full white-label, customisable interface with hierarchy built in for network expansion ease.
For more information, please visit: https://www.optty.com/
About Triple-A
Triple-A is a licensed crypto payment gateway that helps businesses increase their revenue by enabling crypto payments and payouts, giving them access to the spending power of the fast-growing 420m+ cryptocurrency users.
Triple-A's white label crypto payments solutions allow businesses from all industries to leverage the benefits of the growing crypto market without being exposed to volatility risk or having to handle or convert digital currencies. Their solutions are compatible with all wallets, easy to integrate and offer instant confirmation, locked-in exchange rates and chargeback protection.
Licensed by the Monetary Authority of Singapore (MAS) and trusted by over 15,000 businesses, Triple-A makes accepting crypto payments simple for businesses across the globe.
For more information, please visit https://triple-a.io/.
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SOURCE Optty | https://www.weau.com/prnewswire/2023/07/31/optty-partners-with-triple-a-expand-payment-architectures-into-cryptocurrencies/ | 2023-07-31T05:03:25 | 1 | https://www.weau.com/prnewswire/2023/07/31/optty-partners-with-triple-a-expand-payment-architectures-into-cryptocurrencies/ |
Pets of the Week
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Husband pleads guilty to driving drunk before fatal crash that killed his wife | https://www.journalgazette.net/local/pets-of-the-week/article_c75edeee-2cbd-11ee-9c95-df19bd5be481.html | 2023-07-31T05:03:27 | 1 | https://www.journalgazette.net/local/pets-of-the-week/article_c75edeee-2cbd-11ee-9c95-df19bd5be481.html |
More experienced principals leave the profession at higher rates
WASHINGTON, July 31, 2023 /PRNewswire/ -- Roughly 1 in 10 (11 percent) public school principals left the profession between the 2020-21 and 2021-22 school years, according to data from the National Teacher and Principal Survey (NTPS) released today by the National Center for Education Statistics (NCES), the statistical center within the U.S. Department of Education's Institute of Education Sciences (IES).
"Principal attrition is higher in public schools than it was 5 years ago, and veteran public school leaders with more years of experience leave the profession at higher rates than those with less experience," said NCES Commissioner Peggy G. Carr. "Principals are critical supports for a school's teachers and learners, and the country needs leaders in every school who are committed to the success of each student. These data are a valuable snapshot for those at the district and state levels who must address the issue of principal turnover in their schools."
Approximately 80 percent of 2020-21 public school principals remained at the same school one year later ("stayers"), which was lower than the percentage of 2016-17 public school principals who were still at their school 1 year later (82 percent). Six percent of 2020-21 public school principals moved to a different school ("movers"), and 11 percent left the principalship ("leavers"). For private school principals in 2020-21, approximately 83 percent remained at the same school during the following school year, 2 percent moved to a different school, and 10 percent left the principalship.
Additionally, among 2020-21 public school principals who somewhat or strongly agreed they would leave the principalship as soon as possible if they could get a higher paying job (about 25 percent), approximately 73 percent stayed the following school year, while about 15 percent left the profession.
"These data are critical to understanding patterns of principal attrition," said NCES Associate Commissioner Chris Chapman. "We are able to observe how principal attrition has changed over the years, as well as how principal attrition and mobility vary based on characteristics of the principals and their schools."
The report released today includes selected findings from the Principal Follow-up Survey (PFS), a longitudinal component of the National Teacher and Principal Survey (NTPS), which is a nationally representative survey of public and private K-12 schools, principals, and teachers in the 50 states and the District of Columbia. Data were collected from January 2022 through June 2022. The sample included about 6,500 public school principals and about 1,800 private school principals, for a total sample size of about 8,300 principals.
The data were collected as a follow-up to the 2020-21 NTPS to provide attrition and mobility information about principals in K-12 public and private schools. The purpose was to ascertain how many principals from the 2020-21 school year still worked as a principal in the same school 1 year later ("stayer"), how many had moved to become a principal in another school ("mover"), and how many were no longer working as a principal ("leaver").
Key Findings
- Of all public school principals in 2020-21, 11 percent left the profession by the 2021-22 school year. This was higher than in 2016-17, when 10 percent of all public school principals had left the profession since 2015-16, but not measurably different from the 2012-13 school year, when 12 percent of all public school principals had left the profession since the previous school year, or from 2008-09, when 12 percent of all public schools had left the profession since the previous school year.
- Of all public school principals in 2020-21 with more than 10 years of experience as a principal at any school, 15 percent left the profession by the 2021-22 school year. Of those principals with 10 years or more experience as a principal in their current school, 16 percent left the profession.
- A higher percentage of school principals 55 years of age or older left the profession compared to principals between 45-54 years of age.
- Among the 9 percent of 2020-21 public school principals with a salary of less than $75,000, 76 percent remained at the same school during the 2021–22 school year, 7 percent moved to a different school, and 13 percent left the principalship.
- Among the 33 percent of 2020-21 public school principals with a salary of $115,000 or more, 81 percent remained at the same school during the 2021-22 school year, 6 percent moved to a different school, and 10 percent left the principalship.
- Among the 62 percent of 2020-21 private school principals with a salary of less than $75,000, 81 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 10 percent left the principalship.
- Among the 13 percent of 2020-21 private school principals with a salary of $115,000 or more, 85 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 8 percent left the principalship.
The National Center for Education Statistics, a principal agency of the U.S. Federal Statistical System, is the statistical center of the U.S. Department of Education and the primary federal entity for collecting and analyzing data related to education in the U.S. and other nations. NCES fulfills a congressional mandate to collect, collate, analyze, and report complete statistics on the condition and progress of American education; conduct and publish reports; and review and report on education activities internationally.
Follow NCES on Twitter, Facebook, LinkedIn, and YouTube and subscribe to the NCES Newsflash to receive email notifications when new data is released.
The Institute of Education Sciences (IES) is the independent and nonpartisan statistics, research, and evaluation arm of the U.S. Department of Education. Its mission is to provide scientific evidence on which to ground education practice and policy and to share this information in formats that are useful and accessible to educators, parents, policymakers, researchers, and the public.
CONTACT: Josh Delarosa, National Center for Education Statistics, ARIS.NCES@ed.gov
James Elias, Hager Sharp, jelias@hagersharp.com
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SOURCE National Center for Education Statistics | https://www.weau.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ | 2023-07-31T05:03:32 | 1 | https://www.weau.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ |
Families have a new child care option in Warsaw thanks to the Early Childhood Alliance, a Fort Wayne-based nonprofit dedicated to providing high-quality early childhood education and support services.
The organization this month announced the opening of public enrollment at its Warsaw location.
Open since January, the IMD Early Learning Center was previously exclusive to employees of Instrumental Machine & Development, a prominent company based in the region, a news release said.
“Our mission at Early Childhood Alliance has always been to create a brighter future for children by providing access to high-quality early childhood education,” CEO Amber Taggart said in a statement. “Through our IMD Early Learning Center, we are excited to open our doors to families in the Warsaw community, offering a nurturing and stimulating environment where children can grow, learn and thrive.”
The release described the center, 328 N. Park Ave., as a state-of-the-art facility offering spacious classrooms, age-appropriate play areas and access to activities that encourage exploration and creativity.
The curriculum focuses on promoting social, emotional, cognitive and physical growth, the release said, adding it was designed to provide a foundation for lifelong learning.
Call 574-213-3336 for information or to enroll.
Visit ecalliance.org for information about the alliance, which supports families, educators and communities in nurturing children’s growth and development from birth to age 5.
Donations
Comcast last week awarded $50,000 to The Literacy Alliance of Fort Wayne to advance economic opportunity through digital literacy and broadband adoption. The company also announced a donation of 250 laptops to the Fort Wayne Housing Authority, Fort Wayne Boys & Girls Clubs, St. Joseph Mission, Fort Wayne Urban League and the Literacy Alliance of Fort Wayne. These donations are part of Project UP, which is Comcast’s $1 billion commitment to advance digital equity.
Lassus Handy Dandy donated school supplies and $4,000 to Fort Wayne Community Schools. The items benefit the FWCS Families in Transition program, which provides services to students experiencing homelessness.
Grants
Huntington and Manchester universities each received a $250,000 planning grant from Lilly Endowment Inc. through its College and Community Collaboration Initiative. Huntington will use the funds to propose a strategic community project for future development in partnership with the city and county of Huntington, the Northeast Indiana Regional Partnership and other local and regional stakeholders. Manchester is exploring collaborative community projects in Wabash County.
The Indiana Arts Commission announced it awarded $4,000 to East Allen County Schools for the arts integrated residency with Heartland Sings at Southwick Elementary School through the Arts Project Support grant program. Through the district’s partnership with Heartland Sings, first grade classes receive art integrated lessons taught by Heartland Sings musicians. The genre of opera is used as a medium to teach Indiana’s English/language arts standards. The artistic instruction helps increase critical and creative thinking, teamwork/collaboration, problem solving, adaptability/resiliency and communication.
Northwest State
Lexis McDowell of Van Wert County and Williams County residents Vanessa Peralez and Alethia Stimpfle were among the Northwest State Community College phlebotomy technician graduates recognized during a pinning ceremony. Jillian Spengler, a medical assisting graduate from Williams County, was also honored.
Program
Indiana is among six states selected to participate in the National Governors Association Center for Best Practices Policy Academy to Advance Youth Apprenticeship. The Policy Academy offers states a yearlong opportunity designed to support them as they develop policy agendas advancing high-quality youth apprenticeship opportunities. Participating states will also receive a $50,000 grant to execute their project activities.
Saint Francis
Several departments at the University of Saint Francis have relocated to the University Support Services building, formerly Fort Financial, at 3102 Spring St. Departments now operating out of the renovated facility include the business office, campus security, information technology, mail room, marketing, Office of Institutional Research and Effectiveness, operations and registrar.
Michelle Fleig-Palmer, Saint Francis master of healthcare administration director, had an article published in the Spring 2023 issue of the “Fort Wayne Medicine Quarterly” titled, “ChatGPT: Creating a New Challenge for Patient-Physician Trust?”
Saint Francis will hold its annual Welcome Weekend for new students Aug. 25 to 27. Events include a cookout, keynote speaker, trivia show, Franny Relay Race, praise and worship session, service, kickoff party and carnival. Early move-ins for students begin Saturday and Aug. 19, with most students moving in Aug. 25.
Scholarship
The Sons of the American Revolution presented an $8,000 scholarship to recent Homestead High School graduate Madeline Phuong on July 15 for her first-place finish in the Joseph S. Rumbaugh Historical Oration Contest held during the SAR National Congress in Orlando, Florida. Her topic was “Deborah Sampson: An American Heroine.” Sampson served in the 4th Massachusetts Regiment during the Revolutionary War and was one of the first women to receive a pension for her military service.
Trine
Goshen Health has added Trine University as a partner to help its registered nurses complete a bachelor of science in nursing. The online program consists of 11 courses and can be completed in one year. Additionally, spouses of nurses in the program are eligible for discounted tuition, and first-year dependent children are eligible for a $2,000 Goshen Health Legacy Scholarship to attend Trine’s Angola campus.
Trine’s chapter of the Society of Automotive Engineers has been reinstated as a collegiate chapter of SAE International, effective with the 2023-24 academic year. | https://www.journalgazette.net/local/schools/education-notebook-early-childhood-alliance-opens-enrollment-at-warsaw-site/article_5c720fde-2a60-11ee-8a42-af7d201f5ceb.html | 2023-07-31T05:03:33 | 1 | https://www.journalgazette.net/local/schools/education-notebook-early-childhood-alliance-opens-enrollment-at-warsaw-site/article_5c720fde-2a60-11ee-8a42-af7d201f5ceb.html |
HANOI, Vietnam, July 31, 2023 /PRNewswire/ -- SeABank's stock (SSB) has been officially selected by the Ho Chi Minh City Stock Exchange (HOSE) to be included in the VN30-Index basket - an index representing the top 30 stocks with the highest market capitalization and liquidity listed on the HOSE.
At the end of the trading session on July 28, 2023, the closing price of SSB's stock was 29,700 VND per share, bringing SeABank's market capitalization to over 72,875 billion VND, equivalent to nearly 3.07 billion USD.
According to the press release, on July 17, 2023, HOSE announced the portfolio of stocks included in the VN30 and VN-Finlead indexes, which would be effective from August 7, 2023. SSB was chosen to be included in the VN30 basket as it met the requirements set by the HOSE Index Rules. With an average market capitalization of nearly 65,000 billion Vietnamese dongs over the past six months, SSB is one of the largest capitalized stocks among those not included in the previous VN30 basket.
Throughout its operations, SeABank prioritizes transparency by providing information to shareholders, partners, and customers, complying with legal regulations, and following the directives of the Government and the State Bank of Vietnam to stabilize the market, ensure smooth operations, and promote business activities, thereby contributing to the country's socio-economic development.
SeABank's stock (SSB) was officially listed on the HOSE on March 24, 2021, with a reference price of 16,800 Vietnamese dongs per share on its first trading day. It has consistently experienced stable growth since then. In June 2023, SeABank successfully issued shares for dividend payment and additional capital from shareholder funds (bonus shares) with a total ratio of 20.3% to increase its charter capital to 24,537 billion Vietnamese dong.
Previously, SSB was also added to the Morgan Stanley Capital Index (MSCI) Frontier Markets Index starting from March 1, 2023. According to experts, stocks included in the MSCI Frontier Markets Index may be targeted by ETF (Exchange Traded Fund) funds that track frontier market stocks. Some funds use this index as a reference for investment or replicate its portfolio.
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SOURCE SeABank | https://www.weau.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ | 2023-07-31T05:03:33 | 0 | https://www.weau.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ |
A federal judge has dismissed a lawsuit Donald Trump filed against CNN in which the former U.S. president claimed that references in news articles or by the network’s hosts to his efforts to overturn the 2020 election as “the Big Lie” were tantamount to comparing him to Adolf Hitler.
Trump had been seeking punitive damages of $475 million in the federal lawsuit filed last October in South Florida, claiming the references hurt his reputation and political career. Trump is a candidate for the 2024 GOP presidential nomination in what is his third run for the presidency as a major-party candidate.
U.S. District Judge Raag Singhal, who was appointed by Trump, said Friday in his ruling that the former president’s defamation claims failed because the references were opinions and not factual statements. Moreover, it was a stretch to believe that, in viewers’ minds, that phrase would connect Trump’s efforts challenging the 2020 election results to Nazi propaganda or Hitler’s genocidal and authoritarian regime, the judge said.
Lansing shooting injures 5, 2 critically
An early morning shooting Sunday in Michigan wounded five people, including two who were listed in critical condition, police said.
Officers responded to reports of a shooting around 1 a.m., the Lansing Police Department said in a statement. The five victims who were transported to a hospital by the Lansing Fire Department ranged in age from 16 to 26 years old, police said.
There was a large crowd at the scene when officers arrived, prompting Lansing police to ask for assistance from other jurisdictions. Several people were detained, and officers found multiple firearms, police said.
‘Barbenheimer’ stays strong at box officeA week later, the “Barbenheimer” boom has not abated. Seven days after Greta Gerwig’s “Barbie” and Christopher Nolan’s “Oppenheimer” conspired to set box office records, the two films held unusually strongly in theaters.
“Barbie” took in a massive $93 million in its second weekend, according to studio estimates Sunday. “Oppenheimer” stayed in second with a robust $46.2 million. Sales for the two movies dipped 43% and 44%, respectively – well shy of the usual week-two drops.
The two movies combined have already surpassed $1 billion in worldwide ticket sales. Paul Dergarabedian, senior media analyst for data firm Comscore, call it “a touchstone moment for movies, moviegoers and movie theaters.”
“Having two movies from rival studios linked in this way and both boosting each other’s fortunes – both box-office wise and it terms of their profile – I don’t know if there’s a comp for this in the annals of box-office history,” he said. “There’s really no comparison for this.”
Bear in California beats heat in Jacuzzi
With the summer heat wave in full swing in Southern California, a backyard pool is a tempting place to take a dip. Even for a bear.
Police in the city of Burbank responded to a report of a bear sighting in a residential neighborhood and found the animal sitting in a Jacuzzi behind one of the homes.
After a short dip, the bear climbed over a wall and headed to a tree behind the home, police said in a statement Friday. Police released a video of the animal in the neighborhood, which is about 10 miles north of Los Angeles and near the Verdugo Mountains.
The Burbank police have issued warnings for residents to avoid bears and to keep all garbage and food locked up to discourage bears from coming to their residences. | https://www.journalgazette.net/news/national/nation-world-briefs/article_68ec6800-2f2d-11ee-8348-2fdf75079a80.html | 2023-07-31T05:03:39 | 0 | https://www.journalgazette.net/news/national/nation-world-briefs/article_68ec6800-2f2d-11ee-8348-2fdf75079a80.html |
NANJING, China, July 31, 2023 /PRNewswire/ -- Nanjing Leads Biolabs Co., Ltd. (hereinafter referred to as "Leads Biolabs" or "Company") announced today that the National Medical Products Administration (NMPA) and the U.S. Food and Drug Administration (FDA) have approved its first-in-human Investigational New Drug (IND) applications for LBL-034, an anti-GPRC5D/CD3 bispecific antibody invented by Leads Biolabs with global intellectual property rights, for the treatment of relapsed/refractory multiple myeloma. Currently, no GPRC5D-targeting antibody has been approved for marketing.
This is a first-in-human, single-arm, multicenter, open-label, dose-escalation and expansion clinical study, and plans to enroll patients with relapsed/refractory multiple myeloma who have failed prior therapies including but not limited to at least one proteasome inhibitor (PI), one immunomodulator (IMiD) as well as other standard treatments. This study aims to evaluate the safety and tolerability of LBL-034, determine the recommended Phase II dose and assess its efficacy in patients with multiple myeloma.
"Despite recent progress and continuous advancements in multiple myeloma, the time between recurrences has been steadily decreasing, particularly as the number of treatment lines increases. This ultimately leads to emergence of relapsed or refractory multiple myeloma, reaffirming its status as an incurable malignant tumor that poses a serious threat to human life. In light of this challenging reality, the urgent need for more effective and innovative treatment options has never been more evident." said Dr. Charles Cai, Chief Medical Officer of Leads Biolabs, "LBL-034 adopts a unique molecular design, which enables the drug to specifically bind to GPRC5D-expressing tumor cells with high affinity, and reduces the risk of non-specific activation of T-cells, thereby enhancing anti-tumor efficacy and reducing potential risk of immunotoxicity. LBL-034 demonstrated robust anti-tumor activities and good safety profile in pre-clinical studies. We adhere to our tradition of innovation and aim to deliver an important, novel and effective treatment option for patients with poor prognosis of relapsed/refractory multiple myeloma."
About GPRC5D:
G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D) is a C-type 7-channel transmembrane receptor protein. GPRC5D is low expressed in normal human tissues but specifically overexpressed in multiple myeloma. The intensity of GPRC5D expression is an independent prognostic factor in multiple myeloma, and its overexpression is significantly associated with reduced overall survival. Therefore, GPRC5D may be an important potential target for the treatment of plasma cell diseases such as multiple myeloma.
About multiple myeloma:
Multiple myeloma is a malignant plasma cell disease caused by abnormal proliferation of clonal plasma cells, accounting for 10-15% of hematologic malignancies and about 1.4% of all malignancies. It is the second most common hematological malignancy in adults after non-Hodgkin's lymphoma and mostly occurs in the elderly. According to the data released by the World Health Organization (WHO), the number of new cases and deaths of multiple myeloma worldwide in 2020 were 176,000 and 117,000 respectively, and the number of new cases and deaths of multiple myeloma in China were 21,000 and 16,000 respectively. Currently, multiple myeloma is still an incurable malignant tumor, and the five-year survival rate of patients is approximately 24.8% in China, 33.3% in Japan, and 46.7% in the United States. In recent years, with the successful development of proteasome inhibitors (PIs), immunomodulatory drugs (IMiDs), selective nuclear output inhibitors, CD38-targeted antibodies, bispecific antibodies, and CAR-T cell therapies, the tumor response rate and survival prognosis have been significantly improved. However, multiple myeloma remains an unmet clinical need for more effective treatments.
About LBL-034:
LBL-034 is a humanized IgG1 subtype asymmetric bispecific antibody targeting both GPRC5D and CD3 and Leads Biolabs fully owns the worldwide intellectual property rights. LBL-034 induces T-cell-mediated killing of myeloma cells by redirecting CD3+ T-cells to myeloma cells expressing GPRC5D.
LBL-034 has the potential to be a transformative best-in-class GPRC5D-targeted immunotherapy for multiple myeloma. Clinical studies are planned to evaluate the safety and efficacy of LBL-034 in patients with relapsed/refractory multiple myeloma.
Nanjing Leads Biolabs Co., Ltd. is a clinical-stage biotechnology company founded in Nanjing by a team of senior U.S.-trained antibody drug developers. Since 2014, Leads Biolabs has been dedicated to the discovery and development of novel antibody drugs with independent intellectual property rights for the treatment of oncology and other major diseases of high unmet medical needs, particularly the challenges in cancer immunotherapy. Our extensive R&D pipeline consist of more than twenty novel tumor immunotherapy molecules based on monoclonal and bispecific antibody technology platforms. Leads Biolabs is committed to providing safe, effective, accessible and affordable new drugs to address the unmet needs of patients around the world.
For more information, please visit: https://www.leadsbiolabs.com
Business contact: bd@leadsbiolabs.com
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SOURCE LEADS BIOLABS | https://www.dakotanewsnow.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ | 2023-07-31T05:03:44 | 1 | https://www.dakotanewsnow.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ |
Parents are getting a big win as their kids go back to school this year: no more textbook fees. But as the details unfold, school districts around the state are preparing for a shortfall between what the state is going to give them and what the actual costs are.
Lawmakers, pushed by GOP Gov. Eric Holcomb, did the right thing in the state budget and eliminated those pesky fees, which sometimes cost parents hundreds of dollars per child.
Indiana was one of only seven states to charge the fees even though the state constitution requires a free public education.
But there are questions about whether legislators set aside enough money to make up the costs.
Hamilton Heights School Corporation and Greenfield-Central’s superintendents told Fox59 the money the schools will receive won’t be enough to cover the full costs. And Community School Corporation of Southern Hancock County told the Daily Reporter it will have a shortfall of about $800,000.
To start, this is about more than textbooks; it’s about “curricular materials.”
The Indiana Department of Education defines that as “books; hardware that will be consumed, accessed, or used by a single student during a semester or school year; computer software; and digital content.”
Importantly, that includes one-to-one laptops or tablets given to students in some districts.
The general plan moving forward is this: Schools in the coming weeks and months will send in their curricular costs to the Indiana Department of Education. Officials there will then take the total and divide it by the number of students statewide. That will give an amount per student that will be multiplied by how many students each district has. Then, that amount will be given in one lump sum to individual school districts in December.
Lawmakers appropriated $160 million for the initiative’s inaugural year, based on an estimate of $150 per student for the state’s 1 million pupils.
But where did that $150 number come from, and is it really enough?
State Budget Director Zac Jackson said the $151.88 average was calculated using the Free and Reduced Lunch reimbursement claims submitted to the Department of Education by school corporations for fiscal year 2022.
Previously, the state would reimburse districts for curricular materials for just those students on free and reduced lunch: $66.9 million in claims for a total of 440,491 students, averaging $151.88 per student.
So that average was applied to all students to come up with the appropriation in the budget.
Jackson does acknowledge the average will likely be enough to cover some school districts’ actual costs, but not all.
For instance, $151 is clearly not enough to cover the cost of a laptop or tablet in one-to-one schools. And some high school students taking college-level dual credit courses will have more expensive textbooks.
“There probably are some growing pains with this,” Jackson said.
The law specifically says schools can’t charge parents for curricular materials anymore, so districts will have to cover the remaining cost through their tuition support appropriations. Jackson and others note the legislature increased funding to schools in the most recent budget.
Various school officials have talked about being creative, including Business Director Mark Snyder at Southwest Allen County Schools. During a recent school board discussion, he said he anticipates a “significant loss in revenue. It doesn’t mean we can’t do something – it just means we’re going to have to be creative.”
A board member mentioned backlash the state might receive, but Snyder also reminded her that voters will be happy with annual savings of between $150 and $500.
Lawmakers made the right call in eliminating the fees. And I hope they do the same next year and supplement the funding if it is found that some districts are losing money that could otherwise go to teacher salaries and other necessary expenses.
Niki Kelly is editor of the Indiana Capital Chronicle (indianacapitalchronicle.com), where this originally appeared. She covered the Statehouse for The Journal Gazette from 1999 to 2022. | https://www.journalgazette.net/opinion/columnists/textbook-fee-elimination-will-require-adjustments/article_426a26f0-2d47-11ee-acc9-a33e35a36801.html | 2023-07-31T05:03:49 | 0 | https://www.journalgazette.net/opinion/columnists/textbook-fee-elimination-will-require-adjustments/article_426a26f0-2d47-11ee-acc9-a33e35a36801.html |
Partnership adds cryptocurrency as a payment option for merchants using Optty's universal payment platform
SINGAPORE, July 30, 2023 /PRNewswire/ -- Optty, the world's first universal payments platform, today announced a new partnership with Triple-A, a licensed crypto payment gateway, to add cryptocurrency as a payment option on the platform. As the central hub connecting and streamlining a robust global network of Buy Now Pay Later (BNPL) providers, this milestone marks the launch of Optty's sixth payment architecture, further expanding viable payment options for merchants and convenience for their end customers.
Sign-up and integration with Optty is free. To get started, please visit: https://www.optty.com/merchant-account
"As the world's first true universal payments platform, Optty is agnostic and supportive of payments inclusion, a unique position that is designed to help retailers offer more choice than ever at checkout," said Natasha Zurnamer, CEO and founder of Optty. "With one simplified integration, not only can retailers access over 90 BNPLs and local payment methods in over 120 countries — they can now switch on crypto payments, a natural progression in our aim to simplify payments for retailers all over the world."
The first crypto payment gateway to be licensed by the Monetary Authority of Singapore, Triple-A is also licensed in Europe, through Banque de France's ACPR, and registered with the United States Financial Crimes Enforcement Network (FinCEN). Through the collaboration with Triple-A's white label crypto payment gateway, Optty enables retailers and merchants to offer a wide range of payment methods. This allows them to test and learn which payment types best resonate with their customers.
Tapping into diverse consumer payment preferences
With Optty's vast global network of gateways that license the company's unique payment stacks, merchants and retailers can now leverage Triple-A's gateway to accept cryptocurrencies such as Bitcoin (BTC), Ethereum (ETH), Tether (USDT), and USD Coin (USDC). Triple-A's crypto payment gateway is compatible with all crypto wallets, allowing customers to make hassle-free payments using their preferred wallet.
Through real-time crypto-to-fiat conversions facilitated by Triple-A, retailers can receive payments in cryptocurrencies without the need to manage them on their balance sheets and constantly monitor fluctuating exchange rates. Retailers enjoy next-day local currency bank settlements in 50+ currencies, enabling quick access to funds in their preferred currency. Additionally, businesses have the option to offer their customers the convenience of paying through Binance Pay.
Optty already offers Buy Now Pay Later, Debit and Credit, Digital Wallets, Peer to Peer payments, and bank transfer options, and the addition of crypto enables merchants to tap into the spending power of 420 million crypto owners worldwide. Optty plans to further expand payment architectures to a total of nine by the end of 2023.
"We are excited to partner with Optty and bring crypto payments to their merchants," said Eric Barbier, CEO of Triple-A. "This collaboration will help merchants take advantage of the growing demand for cryptocurrency payments, without the hassle of managing crypto assets on their balance sheets."
Disruption through simplification
Previously, retailers and merchants would need to spend a great deal of time and money on complex, one-by-one payment integration processes. Optty changed all this by eliminating it, revolutionizing the way merchants access payments methods globally. Available across ecommerce, IVR, and in-store, it is a true PaaS that offers retailers a simplified integration while providing a seamless and direct commercial partnership channel, enabling an application process with every payment provider in the solution.
About Optty
As a PaaS, Optty is the world's first true universal payments platform that integrates over 90 installment (BNPL) brands — more than any other existing single integration solution globally — and offers six payment architectures, soon to be nine by the end of 2023. Its payments-, partner- and channel-agnostic approach delivers wide payments connectivity globally to schemes, acquirers, gateways and retailers alike and offers a full white-label, customisable interface with hierarchy built in for network expansion ease.
For more information, please visit: https://www.optty.com/
About Triple-A
Triple-A is a licensed crypto payment gateway that helps businesses increase their revenue by enabling crypto payments and payouts, giving them access to the spending power of the fast-growing 420m+ cryptocurrency users.
Triple-A's white label crypto payments solutions allow businesses from all industries to leverage the benefits of the growing crypto market without being exposed to volatility risk or having to handle or convert digital currencies. Their solutions are compatible with all wallets, easy to integrate and offer instant confirmation, locked-in exchange rates and chargeback protection.
Licensed by the Monetary Authority of Singapore (MAS) and trusted by over 15,000 businesses, Triple-A makes accepting crypto payments simple for businesses across the globe.
For more information, please visit https://triple-a.io/.
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SOURCE Optty | https://www.dakotanewsnow.com/prnewswire/2023/07/31/optty-partners-with-triple-a-expand-payment-architectures-into-cryptocurrencies/ | 2023-07-31T05:03:51 | 0 | https://www.dakotanewsnow.com/prnewswire/2023/07/31/optty-partners-with-triple-a-expand-payment-architectures-into-cryptocurrencies/ |
1 The organization recently started construction on a new shelter on Leesburg Road. What will more space allow you to do?
A: Our new 25,000-square-foot building, named in memory of Sharon Bodenhafer, will enable us to nearly triple the number of adoptable animals we can help.
Our current shelter on Hanna Street features just 16 dog kennels, for example, while our new shelter calls for the construction of 41. The design will create a spacious, welcoming environment for adopters and calmer, quieter kennels for the dogs.
Plus, we’ll increase our capacity for feline care as we grow from just two adoptable cat colonies to six colonies that include special habitats specifically designed for both kittens as well as adult cats, especially those who prefer to live without the company of other felines.
The new building will also feature an indoor dog training facility, so the shelter dogs can get physical enrichment, even on inclement days.
And finally, we’ll have an education center in which we can offer staff trainings as well as symposiums for our shelter partners and the greater community.
Best of all, our new home will allow us to combine our shelter and clinic programs under one roof which will streamline our services, resulting in both better time management and cross-departmental communication for our staff and less stress for the animals in our care.
2 Will you keep the Hanna Street building?
A: Yes! We’re as excited for the future of our Hanna Street building as we are for our new location.
In 2015, we introduced our community to our Pet Promises program, which is a comprehensive social service delivery system aimed at helping pets and the people who love them. Through Pet Promises, we offer things like free pet food, access to free vaccines, assistance with pet care for elderly or disabled pet owners, emergency boarding for the pets of people in crisis, etc.
Once we vacate our Hanna Street facility, we’ll repurpose our beloved flagship location and launch the State of Indiana’s only free-standing social service agency aiding pets and their human families. And those 16 kennels at Hanna Street will be used to provide housing for natural disaster response for displaced animals, temporary overflow housing, expanded emergency foster services, and even allow us to collaborate on more national cases like the 2022 Envigo beagle rescue.
3 You’re a leading voice against Indiana’s puppy mill industry. What should people know about mills?
A: Puppy mills and backyard breeders are directly linked to the number of dogs dying in animal shelters, and northeast Indiana is home to dozens of those inhumane mills and disreputable breeders.
The hard truth is that most citizens don’t know how to spot a puppy mill, backyard breeder or even a puppy broker until it’s too late.
Dogs bred at these types of facilities are slickly marketed to unsuspecting consumers who just want to get a cute animal. And once on site, pressure from the sellers leaves buyers feeling they can’t exit without taking a puppy home.
What’s worse is that animals are being bred in deplorable conditions right in our region.
When families acquire these animals – even with the best intentions – they are supporting an industry that cares only about its bottom line, with little regard for the animals themselves. Change must be legislated at the local and state level, and efforts are being made to limit the reach of puppy mills and their pipelines to retail outlets.
For those people who are seeking a specific breed of pet, we encourage contacting our local kennel club to inquire about reputable breeders or breed-specific rescues. And of course, folks should check their local shelters. At Humane Fort Wayne, we often have a wonderful selection of sought-after breeds including my personal favorite: the friendly mixed-breed mutt!
4 What wisdom can you offer a family or person looking to adopt an animal?
A: I frequently hear that people would like to get a dog, but they worry that, because they work, they won’t have time for a new pet. I gently remind them that shelter dogs won’t mind being crated while you’re gone (they sleep most of the day anyway!). In truth, they’re in shelter cages all day now, and they’d relish a chance to become a part of a loving family.
Today there are so many services for pet owners, such as dog day care, independent dog walkers, dog parks, pet sitters, etc. All we ask of adopters is that they are prepared to provide a loving home and routine veterinary care for their new pet.
And when you adopt from a reputable shelter, many of those first services have already been provided. Each animal has been spayed or neutered, vaccinated, tested for disease and microchipped. At Humane Fort Wayne, we’re your partner for the life of your adopted animal! We’re here to help address issues as they arise post-adoption, and we offer a myriad of services to support our customers.
We’re known for affordable adoptions, yes, but the reality is that when someone adopts, they’re literally saving a life – and to us, there’s nothing more priceless.
5 How has your role changed with Humane Fort Wayne since you arrived in the fall of 2012?
A: A better question might be how hasn’t it changed?
When I was first hired by the then Allen County SPCA, I followed in the footsteps of several other directors, none of whom had served the organization longer than two years. I wanted to provide some stability to this decades-old, revered institution while, at the same time, make changes that would improve our visibility, increase adoptions, and save more lives.
In 2012, I had 12 full- and part-time staff, and we were sending home about 600 pets per year. Today, through strategic initiatives that include two mergers, we now have more than 50 staff, and our numerous programs serve and save more than 30,000 animals per year. I’m indebted to the board and team that’s helped make that happen.
It was at my beloved father’s funeral that I vowed to do more with my time on this earth, and I feel very fortunate to have been given this opportunity to do just that. I hope that I have made a positive impact on the lives of the animals (and their humans) in this community because they’ve certainly made an impact on mine. | https://www.journalgazette.net/opinion/editorials/five-questions-for-jessica-henry-johnson-executive-director-humane-fort-wayne/article_1b5b5bf8-2d4a-11ee-b5ec-bf096a8172aa.html | 2023-07-31T05:03:55 | 0 | https://www.journalgazette.net/opinion/editorials/five-questions-for-jessica-henry-johnson-executive-director-humane-fort-wayne/article_1b5b5bf8-2d4a-11ee-b5ec-bf096a8172aa.html |
More experienced principals leave the profession at higher rates
WASHINGTON, July 31, 2023 /PRNewswire/ -- Roughly 1 in 10 (11 percent) public school principals left the profession between the 2020-21 and 2021-22 school years, according to data from the National Teacher and Principal Survey (NTPS) released today by the National Center for Education Statistics (NCES), the statistical center within the U.S. Department of Education's Institute of Education Sciences (IES).
"Principal attrition is higher in public schools than it was 5 years ago, and veteran public school leaders with more years of experience leave the profession at higher rates than those with less experience," said NCES Commissioner Peggy G. Carr. "Principals are critical supports for a school's teachers and learners, and the country needs leaders in every school who are committed to the success of each student. These data are a valuable snapshot for those at the district and state levels who must address the issue of principal turnover in their schools."
Approximately 80 percent of 2020-21 public school principals remained at the same school one year later ("stayers"), which was lower than the percentage of 2016-17 public school principals who were still at their school 1 year later (82 percent). Six percent of 2020-21 public school principals moved to a different school ("movers"), and 11 percent left the principalship ("leavers"). For private school principals in 2020-21, approximately 83 percent remained at the same school during the following school year, 2 percent moved to a different school, and 10 percent left the principalship.
Additionally, among 2020-21 public school principals who somewhat or strongly agreed they would leave the principalship as soon as possible if they could get a higher paying job (about 25 percent), approximately 73 percent stayed the following school year, while about 15 percent left the profession.
"These data are critical to understanding patterns of principal attrition," said NCES Associate Commissioner Chris Chapman. "We are able to observe how principal attrition has changed over the years, as well as how principal attrition and mobility vary based on characteristics of the principals and their schools."
The report released today includes selected findings from the Principal Follow-up Survey (PFS), a longitudinal component of the National Teacher and Principal Survey (NTPS), which is a nationally representative survey of public and private K-12 schools, principals, and teachers in the 50 states and the District of Columbia. Data were collected from January 2022 through June 2022. The sample included about 6,500 public school principals and about 1,800 private school principals, for a total sample size of about 8,300 principals.
The data were collected as a follow-up to the 2020-21 NTPS to provide attrition and mobility information about principals in K-12 public and private schools. The purpose was to ascertain how many principals from the 2020-21 school year still worked as a principal in the same school 1 year later ("stayer"), how many had moved to become a principal in another school ("mover"), and how many were no longer working as a principal ("leaver").
Key Findings
- Of all public school principals in 2020-21, 11 percent left the profession by the 2021-22 school year. This was higher than in 2016-17, when 10 percent of all public school principals had left the profession since 2015-16, but not measurably different from the 2012-13 school year, when 12 percent of all public school principals had left the profession since the previous school year, or from 2008-09, when 12 percent of all public schools had left the profession since the previous school year.
- Of all public school principals in 2020-21 with more than 10 years of experience as a principal at any school, 15 percent left the profession by the 2021-22 school year. Of those principals with 10 years or more experience as a principal in their current school, 16 percent left the profession.
- A higher percentage of school principals 55 years of age or older left the profession compared to principals between 45-54 years of age.
- Among the 9 percent of 2020-21 public school principals with a salary of less than $75,000, 76 percent remained at the same school during the 2021–22 school year, 7 percent moved to a different school, and 13 percent left the principalship.
- Among the 33 percent of 2020-21 public school principals with a salary of $115,000 or more, 81 percent remained at the same school during the 2021-22 school year, 6 percent moved to a different school, and 10 percent left the principalship.
- Among the 62 percent of 2020-21 private school principals with a salary of less than $75,000, 81 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 10 percent left the principalship.
- Among the 13 percent of 2020-21 private school principals with a salary of $115,000 or more, 85 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 8 percent left the principalship.
The National Center for Education Statistics, a principal agency of the U.S. Federal Statistical System, is the statistical center of the U.S. Department of Education and the primary federal entity for collecting and analyzing data related to education in the U.S. and other nations. NCES fulfills a congressional mandate to collect, collate, analyze, and report complete statistics on the condition and progress of American education; conduct and publish reports; and review and report on education activities internationally.
Follow NCES on Twitter, Facebook, LinkedIn, and YouTube and subscribe to the NCES Newsflash to receive email notifications when new data is released.
The Institute of Education Sciences (IES) is the independent and nonpartisan statistics, research, and evaluation arm of the U.S. Department of Education. Its mission is to provide scientific evidence on which to ground education practice and policy and to share this information in formats that are useful and accessible to educators, parents, policymakers, researchers, and the public.
CONTACT: Josh Delarosa, National Center for Education Statistics, ARIS.NCES@ed.gov
James Elias, Hager Sharp, jelias@hagersharp.com
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SOURCE National Center for Education Statistics | https://www.dakotanewsnow.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ | 2023-07-31T05:03:58 | 1 | https://www.dakotanewsnow.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ |
(T) – taped (JIP) – joined in progress
TELEVISION
BASEBALL
MLB, teams TBD, MLB Net, 7 p.m.
MLB, Cincinnati-Chicago Cubs, Bally Indiana/Marquee, 8 p.m.
BASKETBALL
TBT, teams TBD, ESPN, 7 p.m./ESPN2, 9 p.m.
SOCCER
World Cup, Canada-Australia, Fox, 6 a.m.
World Cup, Ireland-Nigeria, FS1, 6 a.m.
Leagues Cup, Puebla-Chicago FC, FS1, 8 p.m.
Leagues Cup, Chivas Guadalajara-Sporting Kansas City, FS1, 10 p.m.
World Cup, Portugal-U.S., Fox, 3 a.m. (Tue.)
World Cup, Vietnam-Netherlands, FS1, 3 a.m. (Tue.)
RADIO
BASEBALL
MLB, Cincinnati-Chicago Cubs, 92.7 FM, 8 p.m.
TV, radio listings subject to change | https://www.journalgazette.net/sports/073123-lineup/article_3b81afc8-2f29-11ee-879e-2bcb5ede51d8.html | 2023-07-31T05:04:01 | 0 | https://www.journalgazette.net/sports/073123-lineup/article_3b81afc8-2f29-11ee-879e-2bcb5ede51d8.html |
HANOI, Vietnam, July 31, 2023 /PRNewswire/ -- SeABank's stock (SSB) has been officially selected by the Ho Chi Minh City Stock Exchange (HOSE) to be included in the VN30-Index basket - an index representing the top 30 stocks with the highest market capitalization and liquidity listed on the HOSE.
At the end of the trading session on July 28, 2023, the closing price of SSB's stock was 29,700 VND per share, bringing SeABank's market capitalization to over 72,875 billion VND, equivalent to nearly 3.07 billion USD.
According to the press release, on July 17, 2023, HOSE announced the portfolio of stocks included in the VN30 and VN-Finlead indexes, which would be effective from August 7, 2023. SSB was chosen to be included in the VN30 basket as it met the requirements set by the HOSE Index Rules. With an average market capitalization of nearly 65,000 billion Vietnamese dongs over the past six months, SSB is one of the largest capitalized stocks among those not included in the previous VN30 basket.
Throughout its operations, SeABank prioritizes transparency by providing information to shareholders, partners, and customers, complying with legal regulations, and following the directives of the Government and the State Bank of Vietnam to stabilize the market, ensure smooth operations, and promote business activities, thereby contributing to the country's socio-economic development.
SeABank's stock (SSB) was officially listed on the HOSE on March 24, 2021, with a reference price of 16,800 Vietnamese dongs per share on its first trading day. It has consistently experienced stable growth since then. In June 2023, SeABank successfully issued shares for dividend payment and additional capital from shareholder funds (bonus shares) with a total ratio of 20.3% to increase its charter capital to 24,537 billion Vietnamese dong.
Previously, SSB was also added to the Morgan Stanley Capital Index (MSCI) Frontier Markets Index starting from March 1, 2023. According to experts, stocks included in the MSCI Frontier Markets Index may be targeted by ETF (Exchange Traded Fund) funds that track frontier market stocks. Some funds use this index as a reference for investment or replicate its portfolio.
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SOURCE SeABank | https://www.dakotanewsnow.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ | 2023-07-31T05:04:04 | 0 | https://www.dakotanewsnow.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ |
BLAINE, Minn. – Lee Hodges rarely gets rattled, except perhaps during Alabama football games when he’s rooting for his beloved Crimson Tide.
After using that unflappable demeanor to keep control of the 3M Open, Hodges finally let loose.
Hodges shot a 67 in the final round Sunday for a wire-to-wire title at the 3M Open and his first tour victory, setting tournament records with a 260 and a seven-stroke win.
“The process I went through, I’ll take this week forever,” Hodges said. “I’ll just try to keep replicating this week every time I show up to a tournament.”
Hodges, who started the day with a five-stroke lead on J.T. Poston, was up by three entering the par-5 last hole on his 65th career start. After Poston’s go-for-broke approach yielded a triple bogey, Hodges tapped in a short putt for his third birdie of the round.
“I had to try and give it a shot and see if there was some way I could make 3 there at the end and put some pressure on Lee,” Poston said.
The 28-year-old Alabama native hugged and hoisted his wife, Savannah, in celebration after she hustled out to the green to greet him. Then Jay Seawell, Hodges’ college coach at Alabama, surprised him with a special appearance and a milkshake in hand. Not bad for a guy from the small town of Ardmore.
“I’m super proud to be from there and represent those people,” Hodges said. “Man, I’m sure there is a party going on in north Alabama right now.”
Poston shot a 69 to drop into a three-way tie for second place with Martin Laird and Kevin Streelman. Dylan Wu shot a 64 to match Keith Mitchell for fifth at 16 under.
Tony Finau, the defending champion and highest-ranked player at 10th in the FedEx Cup standings participating in this field, shot a 70 to land in a three-way tie for seventh.
Hodges shot a 63 on Thursday, a 64 on Friday and a 66 on Saturday to take a commanding lead into the final round at the TPC Twin Cities. Hodges set the 54-hole tournament record at 193.
LPGA: In Évian-Les-Bains, Céline Boutier carded a final round of 3-under 68 to win the Évian Championship by six shots for her first major title.
The 29-year-old Boutier finished at 14-under 270 overall. She is the first Frenchwoman to win the tournament, which became a major in 2013.
She says winning the tournament has been her “biggest dream” since she started watching golf. Boutier had never finished better than 29th in six previous appearances here.
Second-place Brooke Henderson of Canada had a final round of 70.
CHAMPIONS: In Bridgend, Wales, Germany’s Alex Cejka prevailed over Ireland’s Padraig Harrington on the second playoff hole to win the Senior British Open at Royal Porthcawl.
Cejka birdied the second extra hole to claim his third senior major title after he and Harrington had finished tied on 5-over par following a final round played in miserable wet and windy conditions.
Harrington also finished runner-up to Darren Clarke last year.
He narrowly missed an eagle putt on the first extra hole Sunday and could only make par when the players returned to the 18th. The tournament is the last of five majors on the senior schedule. | https://www.journalgazette.net/sports/golf/sundays-golf-roundup-hodges-rolls-to-first-pga-victory-at-3m-more/article_19f0b1ce-2f1a-11ee-9684-13a6604e4d78.html | 2023-07-31T05:04:07 | 0 | https://www.journalgazette.net/sports/golf/sundays-golf-roundup-hodges-rolls-to-first-pga-victory-at-3m-more/article_19f0b1ce-2f1a-11ee-9684-13a6604e4d78.html |
ST. LOUIS – Steven Matz and two relievers combined on a five-hitter, and the St. Louis Cardinals snapped the Chicago Cubs’ eight-game winning streak with a 3-0 victory Sunday.
Tyler O’Neill, Andrew Knizner and Paul Goldschmidt drove in runs in the first two innings for the Cardinals before the pitchers took it from there.
Matz (2-7) allowed four hits in six innings with two strikeouts and no walks. He has not allowed an earned run over his last two starts, covering 12 innings.
Giovanny Gallegos tossed two hitless innings. JoJo Romero threw a scoreless ninth to pick up his first save in his 56th career appearance.
Matz was 0-6 with a 5.72 ERA before being demoted to the bullpen after giving up six earned runs in four innings of a 10-3 loss at Cincinnati on May 24. He made 10 bullpen appearances and was put back into the starting rotation on July 9.
St. Louis salvaged the final game of the four-game set and had lost its previous six home games to the Cubs.
Chicago starter Kyle Hendricks (4-5) allowed three runs on eight hits over seven innings. He entered with a 13-3 career mark against St. Louis.”
Interleague
MARLINS 8, TIGERS 6: At Miami, Garrett Cooper and Jean Segura homered, newly acquired relievers Jorge López and David Robertson played key roles for Miami.
López (5-2) got the last two outs in the seventh and Robertson closed with a perfect ninth in his Marlins debut for his 16th save.
American
GUARDIANS 5, WHITE SOX 0: At Chicago, José Ramírez homered twice and drove in three runs, helping Aaron Civale and Cleveland.
Steven Kwan also homered in manager Terry Francona’s 1,927th win, breaking a tie with Casey Stengel for 13th on the career list. Civale, a potential trade target ahead of Tuesday’s deadline, is 3-0 with a 2.08 ERA in his last seven starts.
National
REDS 9, DODGERS 0: At Los Angeles, Elly De La Cruz, Joey Votto and Matt McLain homered, and Cincinnati took over sole possession of first place in the NL Central.
De La Cruz went 4 for 5 and scored twice as the Reds rapped out 14 hits in taking two of three from the NL West-leading Dodgers.
Cincinnati’s Graham Ashcraft scattered five hits over six innings and struck out two.
BRAVES 8, BREWERS 6: At Atlanta, Matt Olson drove in five runs with two homers, including a go-ahead, two-run blast in the eighth, and Atlanta finished off a sweep of Milwaukee.
Olson has 35 homers, the most in the NL, and 88 RBI, the most in the majors.
METS 5, NATIONALS 2: At New York, Justin Verlander earned his 250th career victory in what could be his final start for New York.
Verlander (6-5) became the 49th major leaguer to reach 250 wins and the first since CC Sabathia for the New York Yankees on June 19, 2019. He is 4-1 with a 1.69 ERA in six starts this month. | https://www.journalgazette.net/sports/professional/mlb/sundays-mlb-roundup-cardinals-stop-cubs-win-streak-more/article_17e76e46-2f19-11ee-a89e-c73992fecb4d.html | 2023-07-31T05:04:14 | 0 | https://www.journalgazette.net/sports/professional/mlb/sundays-mlb-roundup-cardinals-stop-cubs-win-streak-more/article_17e76e46-2f19-11ee-a89e-c73992fecb4d.html |
DUNEDIN, New Zealand – New Zealand outshot Switzerland and even moved goalkeeper Victoria Esson into an attack position several times but failed to break a 0-0 tie Sunday in the Women’s World Cup and became the first host nation to be eliminated in group play in tournament history.
The Football Ferns are co-hosting the World Cup with Australia, which must win today against Canada to avoid its own early elimination.
“Just gutted, I think. Obviously we talked and we were proud of ourselves and what we’ve been able to accomplish, but at the end of the day we wanted to get out of this group stage and we just didn’t. It’s just black and white. So, obviously gutted,” said New Zealand midfielder Malia Steinmetz of the elimination.
Switzerland advanced to the round of 16. The Swiss also played to a scoreless draw against Norway, but won the group with the draw against New Zealand, coupled with the Norwegians’ simultaneous 6-0 rout of the Philippines.
New Zealand controlled the pace for long stretches and had its chances to score, outshooting Switzerland 12-3. Jacqui Hand knocked a shot off the right post in the 24th minute.
COLOMBIA 2, GERMANY 1: In Sydney, Linda Caicedo put the Colombians on course for an upset and Manuela Vanegas clinched the win in the seventh minute of stoppage time against the two-time champions.
Vanegas headed in to settle a thrilling game and put her country on the brink of advancing to the knockout stage.
Alexandra Popp had scored an 89th-minute penalty and seemed to have earned Germany a 1-1 draw after 18-year-old Caicedo had struck an opener for Colombia.
But Vanegas came up with a late twist to huge celebrations among Colombia fans who dominated the crowd.
On Thursday, Germany faces South Korea.
MOROCCO 1, SOUTH KOREA 0: In Adelaide, Australia, the Moroccans made history in multiple ways during their victory.
Defender Nouhaila Benzina became the first player to wear a Hijab in a World Cup game at the senior level and her teammate Ibtissam Jraïdi scored the Atlas Lionesses’ first goal in the global tournament.
Morocco scored in the sixth minute and were able to make it stand up.
After a lopsided loss against Germany, the victory keeps Morocco in contention to advance to the knockout stage.
Morocco plays Colombia on Thursday.
NORWAY 6, PHILIPPINES 0: In Auckland, New Zealand, Sophie Roman Haug’s three goals kick-started a dormant offense that moved the Norweigians to the knockout stage.
The Philippines’ debut run in the tournament came to an end as Norway scored three goals in the first 31 minutes.
Norway’s spot in the round of 16 was secured when Switzerland and New Zealand simultaneously played to a 0-0 draw and the Norwegians advanced on goal differential. | https://www.journalgazette.net/sports/professional/sundays-womens-world-cup-roundup-swiss-advance-with-0-0-draw-with-host-new-zealand/article_b521a090-2f1a-11ee-baa4-83aefe4c0b16.html | 2023-07-31T05:04:20 | 1 | https://www.journalgazette.net/sports/professional/sundays-womens-world-cup-roundup-swiss-advance-with-0-0-draw-with-host-new-zealand/article_b521a090-2f1a-11ee-baa4-83aefe4c0b16.html |
Graham Pauley homered for the third time in the series against West Michigan and Bodi Rascon pitched five hitless innings, but the TinCaps' bullpen let a late-inning lead get away for the second straight day and Fort Wayne lost to the Whitecaps 6-5 Sunday at LMCU Ballpark in Comstock Park, Michigan.
The loss in the series finale meant the TinCaps (49-47, 17-13 second half) split the six-game series against the Whitecaps after winning three of the first four contests and fell into a tie with Dayton in the race for the Midwest League East Division's second-half playoff spot.
Fort Wayne took a 4-2 lead on RBI singles from Kervin Pichardo and Juan Zabala in the seventh, but West Michigan responded with a four-run eighth against Fort Wayne relievers Ethan Routzahn and Adam Smith, raising the TinCaps' bullpen ERA to a league-worst 4.97. The TinCaps led on four separate occasions in the final two games of the series, but were unable to win either game.
Fort Wayne's bullpen, which was short-handed because of Alan Mundo and Aaron Holiday going on the 7-day injured list Saturday, gave up nine runs in 5 1/3 innings over the final two games of the series.
Trailing 6-4, the TinCaps rallied in the top of the ninth. Pichardo led off with his second single of the day and, after a grounder moved him to second, Nerwilian Cedeño singled him home to cut the deficit to 6-5. With the tying run on first and two outs, Nathan Martorella, the league's leading home run and RBI man, lined out to second to end the game.
Pauley gave Fort Wayne the lead with a two-run blast in the top of the first off Detroit Tigers right-hander Spencer Turnbull, who was making a rehab start with West Michigan. It was Pauley's ninth home run in 27 games with Fort Wayne.
Graham Pauley hits another homer this time against rehabbing big league pitcher Spencer Turnbull pic.twitter.com/mnetCGzL4B
— Giannis Auntiegotapoodle (@TooMuchMortons_) July 30, 2023
No one else in the Midwest League has more than six home runs since Pauley debuted with the TinCaps on June 29. He hit four home runs in 62 games with Low-A Lake Elsinore before getting called up. The former Duke Blue Devil added a single and scored twice Sunday. His .906 on-base plus slugging (OPS) would lead the MWL if he had enough at-bats to qualify.
Rascon walked the first two in the second inning and both runs scored on a Martorella error at first with two outs. The Fort Wayne lefty struck out four and walked three without surrendering a hit, but the Whitecaps ended the no-hit bid with a two-out Andre Lipcius single off Smith in the sixth. Rascon has a 1.33 ERA over his last six starts.
Martorella went 0 for 4 and saw a 15-game on-base streak and 10-game hit streak come to an end. His .861 on-base plus slugging (OPS) is third in the league after briefly rising to first Friday.
Leadoff man Jakob Marsee, who took a game off for the first time all season Saturday, went 2 for 5, ending a 1-for-28 stretch. He scored a run to extend his league-leading total in that category to 73, 14 ahead of Martorella and Cedar Rapids' Emmanuel Rodriguez in second. Marsee also stole his 34th base, which is the third-highest total on the circuit. | https://www.journalgazette.net/sports/professional/tincaps/full-count/tincaps-lose-lead-again-fall-to-whitecaps-despite-another-graham-pauley-homer/article_ef8f835e-2f3e-11ee-8a01-771b09c38265.html | 2023-07-31T05:04:26 | 1 | https://www.journalgazette.net/sports/professional/tincaps/full-count/tincaps-lose-lead-again-fall-to-whitecaps-despite-another-graham-pauley-homer/article_ef8f835e-2f3e-11ee-8a01-771b09c38265.html |
ALBUQUERQUE, N.M. (KRQE) – A national television show highlighting Albuquerque and all it has to offer is said to be a hit. Months after the first episode aired the Albuquerque, realtors behind it said the show is doing exactly what they wanted it to do.
Four months ago, the Salcido duo was getting ready to launch Albuquerque into the national spotlight on “American Dream TV” with the show’s second season called “Selling Albuquerque.”
“A lot of things kind of came to light in the last, I don’t know, three months or so.”
Since the season hit the airwaves, the Albuquerque realtors said the show has put the city on the map and their business has exploded because of it.
“We’ve expanded into Las Cruces. We’re looking to expand into Santa Fe, and then we just locking up a deal to expand into Boston as well.”
They said they’re receiving calls from businesses looking to plant their roots right here in the Duke City. While their personal expansion has led them to put a slight pause on their time with the show, it’s not a permanent one.
“I think we’re definitely open, the way that we left it with them was, it was a good problem. We got really busy with everything that’s happening,”
“Selling Albuquerque” has already highlighted places like the Sandias and Mesa del Sol, as well as the company Twilight Homes that build houses here.
They are on a temporary break from the show, but they have big plans for the next episodes when they return.
“I’d like to kind of go in with like Meow Wolf, for, you know, some of the more fun attractions that Albuquerque has to offer, or New Mexico, has to offer because we’re kind of looking to go all over the state and kind of bring in all that.”
The season “Selling Albuquerque” can be found on the travel channel as well as other streaming services. | https://www.krqe.com/news/albuquerque-metro/local-company-on-national-tv-show-says-business-is-booming/ | 2023-07-31T05:04:29 | 0 | https://www.krqe.com/news/albuquerque-metro/local-company-on-national-tv-show-says-business-is-booming/ |
Fort Wayne’s swim clubs have a new champion.
Autumn Ridge Swim Team wrapped up the Fort Wayne City Swim Meet at Helen P. Brown Natatorium with 2,861.5 points on Sunday. Pocahontas Swim Club was second with 2,512 points, and Pine Valley had its seven-year title streak ended, taking third place with 2,357.5 points. Orchard Ridge was fourth and Arlington Park was fifth.
“It feels really good. I’ve been on the team since 2015, and it’s been a long time coming, I’m really happy about it,” said Maddy McIntosh, who is the co-head coach of Autumn Ridge alongside Jorie Rodenbeck.
“I’m really excited for them. They’ve wanted this for a very long time. So we’re excited that the kids swam fast and were able to bring it home,” Rodenbeck added.
Autumn Ridge had 11 swimmers finish among the top-three scorers in their respective age groups. The club dominated three age groups in particular – Maris Williams and Kate Fetters each scored 57 points to top the 13-14 girls division, while Naomi Bowland was third with 52 points; James Hench took first in the 13-14 boys group with 57 points while Eli Baker was third with 54; and Evan Bushong was the high-point scorer for 15-and-over boys with 58.5 points and Mason Crews was second with 54.
Josie Trent scored 60 points for Autumn Ridge to lead the 11-12 girls division. The other swimmers who earned 60 points for their teams were Eme Dommer of Pine Valley (8-and-under girls), Austin Young of Pine Valley (9-10 boys), Breckin Luckett of Blackhawk Swim and Dive (11-12 boys) and Luca McGee of Pocahontas (15-over girls).
The Autumn Ridge coaches said their youngest swimmers had made a concerted effort to strictly follow the rules and avoid disqualifications, which in recent years had been a common but frustrating experience for the city’s least-experienced swimmers at the summer’s biggest meet.
“I would say our 10-and-unders were really focused on getting legal. The league really cracked down on being legal this year, and our 10-and-unders really wanted to be able to do that. That’s a lot of City, so I think they were a huge key to this,” Rodenbeck said. “We were blown away by the 8-and-under session, how few DQs, so many kids in events doing well. Across the board, everyone worked really hard at it.”
The conclusion of the three-day championship came when Autumn Ridge accepted the enormous City Swim trophy and jumped all together with the trophy into the warm-up pool, the coaches still in their street clothes, the older boys splashing each other, the older girls lifting their youngest teammates onto their shoulders.
“It’s been really exciting, we’ve had a couple older kids step up this year and become coaches as swimmers, so seeing them excel in that leadership role has been really exciting,” McIntosh said, referencing a group that includes Bushong and Natalie Marshall, who scored 47 points in the 15-over girls division.
“And they get excited about the younger kids, and then their friends get excited about the kids they coach,” Rodenbeck added. “It was really cool this year.” | https://www.journalgazette.net/sports/recreation/autumn-ridge-wins-fort-wayne-city-swim-meet/article_86b9fa8c-2f37-11ee-9d03-3b49e3f0331d.html | 2023-07-31T05:04:32 | 0 | https://www.journalgazette.net/sports/recreation/autumn-ridge-wins-fort-wayne-city-swim-meet/article_86b9fa8c-2f37-11ee-9d03-3b49e3f0331d.html |
Climatological and precipitation information provided by the National Weather Service at 7 p.m. daily.
Sunday records
High temperature 83
High one year ago 81
Normal 83
Record: 1999 100
Low temperature 62
Low one year ago 56
Normal 63
Record: 1904 48
Maumee stage 5.5 feet
Cooling degree-days
The difference between the day’s average temperature and a base of 65 degrees.
For Sunday 8
For July 272
Rainfall
For Sunday none
For July 5.28 inches (1.35)
For the year 24.46 inches (0.32)
Relative humidity
Highest 97% at 4 a.m.
Lowest 54% at 3 p.m.
Average 76%
Skywatch
Sunrise 6:35 a.m.
Sunset 8:58 p.m.
Moonrise 8:47 p.m.
Moonset 5:58 a.m. Tuesday
Full Moon
Aug. 1
Last Quarter
Aug. 8
New Moon
Aug. 16
First Quarter
Aug. 24 | https://www.journalgazette.net/weather/weather-journal/article_7af8cd46-2eeb-11ee-aca2-67f59e2dd836.html | 2023-07-31T05:04:38 | 1 | https://www.journalgazette.net/weather/weather-journal/article_7af8cd46-2eeb-11ee-aca2-67f59e2dd836.html |
Erratic winds challenge firefighters battling two major California blazes
MOJAVE NATIONAL PRESERVE, Calif. (AP) — A massive wildfire burning out of control in California’s Mojave National Preserve was spreading rapidly amid erratic winds, while firefighters reported progress against another major blaze to the southwest that prompted evacuations.
The York Fire that erupted Friday near the remote Caruthers Canyon area of the vast wildland preserve crossed the state line into Nevada on Sunday and sent smoke further east into the Las Vegas Valley.
Wind-driven flames 20 feet (6 meters) high in some spots charred more than 110 square miles (284 square kilometers) of desert scrub, juniper and Joshua tree woodland, according to an incident update. There was zero containment.
“The dry fuel acts as a ready ignition source, and when paired with those weather conditions it resulted in long-distance fire run and high flames, leading to extreme fire behavior,” the update said. No structures were threatened.
To the southwest, the Bonny Fire was holding steady at about 3.4 square miles (8.8 square kilometers) in rugged hills of Riverside County. More than 1,300 people were ordered to evacuate their homes Saturday near the community of Aguanga that is home to horse ranches and wineries.
Gusty winds and the chance of thunderstorms into Monday will heighten the risk of renewed growth, the California Department of Forestry and Fire Protection said in a statement.
One firefighter was injured in the blaze, which was 5% contained.
Copyright 2023 The Associated Press. All rights reserved. | https://www.kmvt.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ | 2023-07-31T05:05:03 | 1 | https://www.kmvt.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ |
HONG KONG, July 31, 2023 /PRNewswire/ -- Akeso Inc. ("Akeso", the "Company"; 9926.HK), a commercial-stage biopharmaceutical company focused on developing and commercializing first-in-class and best-in-class innovative medicines globally, today announced that it is expected that the Company will record a profit of not less than RMB2.3 billion for the six months ended June 30, 2023. This is the first time for the Company to achieve half-year profits.
The turnaround from loss to profit during the Reporting Period was mainly attributable to:
- In respect of Ivonescimab (AK112, PD-1/VEGF) independently developed by the Company, the Company has entered into the collaborative and licensing agreement with Summit Therapeutics (details of which are set out in the announcement of the Company dated December 6, 2022). The Company has received the total upfront payment equivalent to US$500 million in full during the first quarter of 2023 (details of which are set out in the announcements of the Company dated January 26, 2023 and March 6, 2023). Part of such upfront payment was recognized as licensing fee income which significantly contributed to the revenue of the Company for the Reporting Period, and amounted to approximately RMB2.9 billion. The revenue recognition of the remaining portion of the upfront payment will be recognized as revenue in batches going forward.
- In respect of the Company's innovative product 开坦尼® (cadonilimab, PD-1/CTLA-4), since its launch in June 2022, it has recorded significant increase of the patients as well as product sales, which reflects the excellent clinical value of cadonilimab. In addition, 安尼可®(penpulimab, PD-1) also continued to contribute to the growth in the Company's product sales revenue during the Reporting Period.
- The Company has continued to optimise its cost management capabilities in a scientific and efficient way and has achieved better results in cost control while accelerating innovative products development and pipelines advancement.
About Akeso
Akeso (HKEX: 09926) is a commercial-stage biopharmaceutical company committed to the discovery, development, manufacturing, and commercialization of innovative medicines with high unmet medical needs worldwide. Founded in 2012, the Company has established a comprehensive in-house drug development platform (ACE Platform) and know-how, including R&D, clinical development, CMC (Chemistry, Manufacturing, and Controls), and commercialization capabilities.
With fully integrated multi-functional platform, Akeso is internally working on a robust pipeline of over 30 innovative assets in the fields of cancer, autoimmune disease, inflammation, metabolic disease, and other major therapeutic areas. 19 assets have entered clinical stage. Leveraging in-house developed bispecific platform technology ("Tetrabody technology"), the Company has advanced four potential first-in-class bispecific antibody drugs into market or clinical development, including cadonilimab (PD-1/CTLA-4), ivonescimab (PD-1/VEGF), PD-1/LAG-3, TIGIT/TGF-Beta bispecific antibodies. In June 2022, cadonilimab was approved by the NMPA and became the first commercialized PD-1 based bispecific drug globally. Another Akeso internally discovered and developed oncology product, penpulimab (a PD-1 antibody), was granted marketing approval in China in August 2021. In December 2022, the Company out-licensed breakthrough bispecific antibody, ivonescimab (PD-1/VEGF bi-specific antibody, AK112), with up to US$5 Billion total potential deal value to Summit Therapeutics for development and commercialization in the U.S., Canada, Europe, and Japan.
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SOURCE Akeso, Inc. | https://www.kmvt.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ | 2023-07-31T05:05:09 | 0 | https://www.kmvt.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ |
SEATTLE, July 30, 2023 /PRNewswire/ -- Monport Laser has been at the forefront of laser engraving innovation, spearheading the development of cutting-edge laser engravers and cutters. Building upon its world-leading expertise in the laser engraving industry, the company is now ready to captivate the market with its latest breakthroughs. In August, Monport Laser is scheduled to announce a range of new laser engraving machines, specifically engineered to handle various materials.
After six months of relentless effort from Monport's development technical team, their eagerly anticipated product will finally be revealed to all laser creators in early August of this year. The development of this innovative machine began with thousands of customer survey questionnaires for laser marking machines, rigorous testing, and product designer assessments. Engineers conducted over a dozen rounds of machine sample screening and in the final design stage, they took the unusual step of bringing in external senior personnel and engraving novices to carry out engraving tests for an entire month. This dedication to improvement and openness to feedback ensures a professional and user-friendly final fiber laser.
Monport GP Fiber Laser Series is not only Lightweight but Compact
Laser engraving machines have long faced difficulties when it comes to laser focusing, causing technical support headaches. Monport's latest innovation in marking machine can answer all these troubles. The new product boasts an electric and manual double lifting focus method, designed to make laser focusing seamless and improve the final engraving result. With this cutting-edge technology, users can operate without any barriers, and achieve the perfect, professional engraving effect.The electric lifting focus is suitable for beginners while the manual focus is the best for experienced users. This new integrated fiber laser is truly versatile in achieving any special engraving effects needed.
Breaking away from the conventional split type designs flooding the market, Monport introduces a game-changing one-piece design for their latest marking machine. This ingenious development not only saves valuable space but also ensures portability becomes a breeze. Bella, a senior developer at Monport Laser, proudly declared, "Our exceptional team of female developers has personally experienced the convenience of this machine. They effortlessly moved it from one studio to another, adjusting the base's height for easy handling right off the table. The commitment to a user-friendly experience is not just a mere claim."
In striking comparison to other conventional 33kg machines, Monport GP Series Fiber Series introduces their groundbreaking 20-22 kg all-in-one machine, setting a new industry standard for its exceptional lightness. The machine boasts rounded leading corners, diligently crafted to prevent unwanted bumps and damage during handling and transportation. Monport's thoughtful consideration extends further with the addition of a dustproof board, ensuring optimal performance and longevity. Endowed with an exceptional user-friendly experience and multifunctional capabilities, this machine embodies Monport Laser's unwavering dedication to continuous upgrades, always keeping the user at the forefront.
Monport GI Series MOPA Lasers Redefine Color Fast Marking
Monport's exciting product launch not only includes the highly anticipated new additions to the GP Series but also showcases the cutting-edge GI Series color engraving fiber machine. This JPT MOPA fiber laser is built to last, offering precision, durability, and longevity that surpasses expectations. With its remarkable laser cutting capability, it can effortlessly cut up to 0.05 mm with each pass, achieving an astonishing accuracy of ±0.1 microns.
Extensive Support and Remarkable Fiber Accessories
Complementing the multitude of advantages offered by their cutting-edge machine, Monport Laser goes above and beyond by providing customers with comprehensive support and unparalleled expandability. The new fiber series from Monport introduces a range of accessories designed to elevate the engraving experience. One notable addition is the safety shells, embedded with radiation protection and noise reduction functions, creating a secure and tranquil environment for users.
As a testament to their commitment to customer satisfaction, Monport Laser also includes 10 different test materials, ranging from metal rings to key chains and cards made from various metal materials, enabling users to explore and experiment with ease.
By empowering businesses and industries, expanding the creative landscape for maker spaces, unleashing innovation, and creating opportunities for growth, Monport Laser is at the forefront of revolutionizing the laser engraving field.
Company: Monport Laser
Contact email: official@monportlaser.com
Pre-sales Phone: (+1)332-251-1208
Monport Laser Website: https://monportlaser.com/
Monport Adress: Monport Tech Inc. 300 LENORA ST 878, SEATTLE, WA, 98121-2411, UNITED STATES
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SOURCE Monport Laser | https://www.kmvt.com/prnewswire/2023/07/31/monport-laser-unveils-new-gp-series-gi-series-fiber-lasers-redefine-precision-performance/ | 2023-07-31T05:05:15 | 0 | https://www.kmvt.com/prnewswire/2023/07/31/monport-laser-unveils-new-gp-series-gi-series-fiber-lasers-redefine-precision-performance/ |
NANJING, China, July 31, 2023 /PRNewswire/ -- Nanjing Leads Biolabs Co., Ltd. (hereinafter referred to as "Leads Biolabs" or "Company") announced today that the National Medical Products Administration (NMPA) and the U.S. Food and Drug Administration (FDA) have approved its first-in-human Investigational New Drug (IND) applications for LBL-034, an anti-GPRC5D/CD3 bispecific antibody invented by Leads Biolabs with global intellectual property rights, for the treatment of relapsed/refractory multiple myeloma. Currently, no GPRC5D-targeting antibody has been approved for marketing.
This is a first-in-human, single-arm, multicenter, open-label, dose-escalation and expansion clinical study, and plans to enroll patients with relapsed/refractory multiple myeloma who have failed prior therapies including but not limited to at least one proteasome inhibitor (PI), one immunomodulator (IMiD) as well as other standard treatments. This study aims to evaluate the safety and tolerability of LBL-034, determine the recommended Phase II dose and assess its efficacy in patients with multiple myeloma.
"Despite recent progress and continuous advancements in multiple myeloma, the time between recurrences has been steadily decreasing, particularly as the number of treatment lines increases. This ultimately leads to emergence of relapsed or refractory multiple myeloma, reaffirming its status as an incurable malignant tumor that poses a serious threat to human life. In light of this challenging reality, the urgent need for more effective and innovative treatment options has never been more evident." said Dr. Charles Cai, Chief Medical Officer of Leads Biolabs, "LBL-034 adopts a unique molecular design, which enables the drug to specifically bind to GPRC5D-expressing tumor cells with high affinity, and reduces the risk of non-specific activation of T-cells, thereby enhancing anti-tumor efficacy and reducing potential risk of immunotoxicity. LBL-034 demonstrated robust anti-tumor activities and good safety profile in pre-clinical studies. We adhere to our tradition of innovation and aim to deliver an important, novel and effective treatment option for patients with poor prognosis of relapsed/refractory multiple myeloma."
About GPRC5D:
G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D) is a C-type 7-channel transmembrane receptor protein. GPRC5D is low expressed in normal human tissues but specifically overexpressed in multiple myeloma. The intensity of GPRC5D expression is an independent prognostic factor in multiple myeloma, and its overexpression is significantly associated with reduced overall survival. Therefore, GPRC5D may be an important potential target for the treatment of plasma cell diseases such as multiple myeloma.
About multiple myeloma:
Multiple myeloma is a malignant plasma cell disease caused by abnormal proliferation of clonal plasma cells, accounting for 10-15% of hematologic malignancies and about 1.4% of all malignancies. It is the second most common hematological malignancy in adults after non-Hodgkin's lymphoma and mostly occurs in the elderly. According to the data released by the World Health Organization (WHO), the number of new cases and deaths of multiple myeloma worldwide in 2020 were 176,000 and 117,000 respectively, and the number of new cases and deaths of multiple myeloma in China were 21,000 and 16,000 respectively. Currently, multiple myeloma is still an incurable malignant tumor, and the five-year survival rate of patients is approximately 24.8% in China, 33.3% in Japan, and 46.7% in the United States. In recent years, with the successful development of proteasome inhibitors (PIs), immunomodulatory drugs (IMiDs), selective nuclear output inhibitors, CD38-targeted antibodies, bispecific antibodies, and CAR-T cell therapies, the tumor response rate and survival prognosis have been significantly improved. However, multiple myeloma remains an unmet clinical need for more effective treatments.
About LBL-034:
LBL-034 is a humanized IgG1 subtype asymmetric bispecific antibody targeting both GPRC5D and CD3 and Leads Biolabs fully owns the worldwide intellectual property rights. LBL-034 induces T-cell-mediated killing of myeloma cells by redirecting CD3+ T-cells to myeloma cells expressing GPRC5D.
LBL-034 has the potential to be a transformative best-in-class GPRC5D-targeted immunotherapy for multiple myeloma. Clinical studies are planned to evaluate the safety and efficacy of LBL-034 in patients with relapsed/refractory multiple myeloma.
Nanjing Leads Biolabs Co., Ltd. is a clinical-stage biotechnology company founded in Nanjing by a team of senior U.S.-trained antibody drug developers. Since 2014, Leads Biolabs has been dedicated to the discovery and development of novel antibody drugs with independent intellectual property rights for the treatment of oncology and other major diseases of high unmet medical needs, particularly the challenges in cancer immunotherapy. Our extensive R&D pipeline consist of more than twenty novel tumor immunotherapy molecules based on monoclonal and bispecific antibody technology platforms. Leads Biolabs is committed to providing safe, effective, accessible and affordable new drugs to address the unmet needs of patients around the world.
For more information, please visit: https://www.leadsbiolabs.com
Business contact: bd@leadsbiolabs.com
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SOURCE LEADS BIOLABS | https://www.kmvt.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ | 2023-07-31T05:05:22 | 0 | https://www.kmvt.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ |