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ATLANTA (AP) — Matt Olson says it's no mystery why he's leading the majors in RBIs.
In Atlanta's powerful lineup, Olson is often hitting with runners on base.
Olson drove in five runs with two homers, including a two-run shot in the eighth, and the Braves beat the Milwaukee Brewers 8-6 on Sunday to cap their sweep of the high-scoring series.
Olson has 35 homers, tops in the NL, and 88 RBIs. The Braves scored 29 runs in the three-game sweep in the matchup of NL contenders.
“There’s always dudes on base,” Olson said. “I feel like I'm rarely taking at-bats with the bases empty.”
The only player in the majors with more homers than Olson is Shohei Ohtani, with 39. Ohtani will bring the Los Angeles Angels into Atlanta for a series beginning Monday night.
With the sweep, the Braves won five of six against the Brewers in the last two weeks, including two of three in Milwaukee on July 21-23.
“You know you're probably not shutting them out,” said Brewers left fielder Christian Yelich, who homered and drove in two runs.
Yelich said a “back-and-forth game” is likely against Atlanta. Sure enough, the Brewers lost despite holding leads of 1-0, 3-2 and 6-5.
“To keep roaring back, it's a testament to how tough these guys are,” Braves manager Brian Snitker said.
Atlanta (67-36) leads the NL East by 11 1/2 games over Miami. Milwaukee’s loss coupled with Cincinnati’s win at the Dodgers dropped the Brewers (57-49) into second in the NL Central.
Orlando Arcia led off the eighth with a double to left against Milwaukee's Joel Payamps (4-2). With one out, Olson's tiebreaking 35th homer landed in the Atlanta bullpen in right-center.
Payamps entered with a string of 17 consecutive scoreless appearances. He had allowed just seven hits in his last 18 innings.
Kirby Yates (5-0) pitched a scoreless eighth for the win. Raisel Iglesias earned his 20th save by striking out the side in the ninth.
Olson's three-run homer lifted the Braves to a 5-3 lead in the third. He drove in Ronald Acuña Jr., who singled and stole second, and Austin Riley, who walked.
Collin McHugh blew the 5-3 lead by giving up three runs in the sixth. William Contreras doubled in two runs for Milwaukee.
Atlanta's Marcell Ozuna tied the game at 6 with his homer off Hoby Milner.
Riley continued his power surge for Atlanta by hitting his eighth homer in the last 11 games in the first, giving him 24 on the year. The two-run shot off Colin Rea carried 463 feet to left-center.
Rea allowed five runs in five innings.
Carlos Santana, acquired from Pittsburgh on Saturday, hit his first homer with the Brewers in the third. The liner over the right-field wall gave Milwaukee a 3-2 lead. Yelich led off the third with his 16th homer.
TRADE
Atlanta added veteran infielder Nicky Lopez in a trade with the Kansas City Royals. The Braves sent left-hander Taylor Hearn to Kansas City for the 28-year-old Lopez, who can play shortstop, second base and third.
ROOKIE RETURNS
Atlanta rookie AJ Smith-Shawver, recalled from Triple-A Gwinnett before the game, allowed three runs and four hits in five innings.
“He's got a great way about him,” Snitker said of the 20-year-old right-hander. “There's no panic in him. ... There's tremendous upside for him as he figures things out.”
FIRST THINGS FIRST
Thanks to Riley's homer, the Braves have scored 109 first-inning runs, the most in the majors by any team in any inning. The Texas Rangers' 90 fourth-inning runs are second on the list.
“We come in ready to swing and ready to do damage,” Ozuna said.
TRAINING ROOM
Brewers: LHP Wade Miley (left elbow) will come off the 15-day injured list to start Wednesday night at Washington. ... RHP Brandon Woodruff (right shoulder) will pitch for Triple-A Nashville on Tuesday. ... RHP Julio Teheran (right hip impingement) was placed on the 15-day IL. RHP Peter Strzelecki was recalled from Nashville.
UP NEXT
Brewers: RHP Corbin Burnes (9-6, 3.46 ERA) is scheduled to pitch Monday night's opener of a three-game series at Washington against RHP Jake Irvin (3-5, 4.96 ERA).
Braves: Atlanta opens an interleague series against the Los Angeles Angels on Monday night. Braves RHP Charlie Morton (10-8, 3.57 ERA) faces RHP Griffin Canning (6-4, 4.46 ERA). Morton is 4-1 with a 3.83 ERA in 10 career starts against the Angels.
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PYEONGTAEK, South Korea (AP) — The dogs bark and stare as Kim Jong-kil approaches the rusty cages housing the large, short-haired animals he sells for their meat. Kim opens a door and pets one dog’s neck and chest.
Kim says he’s proud of the dog meat farm that has supported his family for 27 years, but is upset over growing attempts by politicians and activists to outlaw the business, which he is turning over to his children.
“It’s more than just feeling bad. I absolutely oppose these moves, and we’ll mobilize all our means to resist it,” Kim, 57, said in an interview at his farm in Pyeongtaek city, just south of Seoul.
Dog meat consumption is a centuries-old practice on the Korean Peninsula and has long been viewed as a source of stamina on hot summer days. It's neither explicitly banned nor legalized in South Korea, but more and more people want it prohibited. There's increasing public awareness of animal rights and worries about South Korea’s international image.
The anti-dog meat campaign recently received a big boost when the country’s first lady expressed her support for a ban and two lawmakers submitted bills to eliminate the dog meat trade.
“Foreigners think South Korea is a cultural powerhouse. But the more K-culture increases its international standing, the bigger shock foreigners experience over our dog meat consumption,” said Han Jeoungae, an opposition lawmaker who submitted legislation to outlaw the dog meat industry last month.
Prospects for passage of an anti-dog meat law are unclear because of protests by farmers, restaurant owners and others involved in the dog meat industry. Surveys suggest that one in three South Koreans opposes such a ban, though most people don’t eat dog meat anymore.
Dogs are also eaten in China, Vietnam, Indonesia, North Korea and some African countries, including Ghana, Cameroon, Congo and Nigeria.
Earlier this month, Indonesian authorities announced the end of dog and cat slaughter at an animal market on the island of Sulawesi following a yearslong campaign by local activists and world celebrities. The Tomohon Extreme Market will become the first such market in Indonesia to go dog and cat meat-free, according to the anti-animal cruelty group Humane Society International.
South Korea's dog meat industry receives more international attention because of its reputation as a wealthy, ultra-modern democracy. It is also the only nation with industrial-scale farms. Most farms in South Korea have more than 500 dogs, according to a dog farmers’ association.
During a recent visit, Kim’s farm, one of the country’s largest with 7,000 dogs, appeared relatively clean but there was a strong stench in some areas. All dogs are kept in elevated cages and are fed with food waste and ground chicken. They are rarely released for exercise and typically are sold for meat one year after they are born.
Kim said two of his children, age 29 and 31, are running the farm with him, and that business has been going pretty well. He said the dogs bred for their meat are different from pets, an idea opposed by activists.
It's difficult now to find dog meat restaurants in Seoul’s bustling downtown, though many still exit in the countryside.
“I only earn one-third of the money I used to make. Young people don’t come here. Only ailing old people come for lunch,” said Yoon Chu-wol, 77, the owner of a dog meat restaurant in Seoul’s Kyungdong traditional market. “I tell my elderly customers to come and eat my food more frequently before it’s banned.”
Farmers also face growing scrutiny from officials and increasingly negative public opinion. They complain that officials visit them repeatedly in response to complaints filed by activists and citizens over alleged animal abuse and other wrongdoing. Kim said more than 90 such petitions were filed against his farm during a recent four-month span.
Son Won Hak, general secretary of the dog farmers' association, said many farms have collapsed in recent years because of falling dog meat prices and weaker demand. He thinks that's a result of activist campaigns and unfair media reports focusing on farms with inferior conditions. Some observers, however, say consumption of dog meat was already declining, with younger people staying away from it.
“Quite honestly, I'd like to quit my job tomorrow. We can’t confidently tell our children that we’re raising dogs,” Son said. “When my friends called me, they said ‘Hey, are you still running a dog meat farm? Isn’t it illegal?’”
The number of farms across South Korea has dropped by half from a few years ago to about 3,000 to 4,000, and about 700,000 to 1 million dogs are slaughtered each year, a decline from several million 10 to 20 years ago, according to the dog farmers’ association. Some activists argue that the farmers’ estimates are an exaggeration meant to show their industry is too big to destroy.
In late 2021, South Korea launched a government-civilian task force to consider outlawing dog meat at the suggestion of then-President Moon Jae-in, a pet lover. The committee, whose members include farmers and animal rights activists, has met more than 20 times but hasn’t reached any agreement, apparently because of disputes over compensation issues.
Agriculture officials refused to disclose the discussions in the closed-door meetings. They said the government wants to end dog meat consumption based on a public consensus.
In April, first lady Kim Keon Hee, the wife of current President Yoon Suk Yeol, said in a meeting with activists that she hopes for an end to dog meat consumption. Famers responded with rallies and formal complaints against Kim for allegedly hurting their livelihoods.
Han, the lawmaker, said she “highly positively appraises” influential figures speaking out against dog meat consumption.
Han said her bill offers support programs for farmers who agree to close their farms. They would be entitled to money to dismantle their facilities, vocational training, employment assistance and other benefits, she said.
Ju Yeongbong, an official of the farmers’ association, said farmers want to continue for about 20 more years until older people, their main customers, die, allowing the industry to naturally disappear. Observers say most farmers are also in their 60s to 70s.
Borami Seo, a director of the South Korea office of the Humane Society International, said she opposes the continued killing of millions of dogs for such a prolonged period. “Letting this silent cruelty to (dogs) be committed in South Korea doesn’t make sense,” Seo said.
“(Dog meat consumption) is too anachronistic, has elements of cruelty to animals and hinders our national growth,” said Cheon JinKyung, head of Korea Animal Rights Advocates in Seoul.
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Credit: AP | https://www.springfieldnewssun.com/nation-world/south-korean-dog-meat-farmers-push-back-against-growing-moves-to-outlaw-their-industry/ZDNYR5DNGFGR7NIS2CMMF7EWYY/ | 2023-07-31T05:18:16 | 0 | https://www.springfieldnewssun.com/nation-world/south-korean-dog-meat-farmers-push-back-against-growing-moves-to-outlaw-their-industry/ZDNYR5DNGFGR7NIS2CMMF7EWYY/ |
BANGKOK (AP) — Shares were mostly higher in Asia on Monday after Wall Street got back to climbing following more encouraging profit reports and the latest signal that inflation is loosening its chokehold on the economy.
Sentiment also has been boosted by revived hopes for more stimulus from Beijing for the sluggish Chinese economy. Chinese factory activity contracted in July as export orders shrank, a survey showed, adding to pressure on the ruling Communist Party to reverse an economic slowdown.
A purchasing managers’ index issued by the national statistics agency and an industry group improved to 49.3 from June’s 49 on a 100-point scale but was below the 50-point level that shows activity contracting.
“The PMI surveys suggest that China’s economic recovery continued to lose momentum in July,” Julian Evans-Pritchard of Capital Economics said in a commentary. “Looking forward, policy support is needed to prevent China’s economy from slipping into a recession, not least because external headwinds look set to persist for a while longer."
The Hang Seng in Hong Kong rose 1.5% to 20,208.78 while the Shanghai Composite index advanced 0.6% to 3,296.58.
Tokyo's Nikkei 225 index was up 1.1% at 33,133.39. In Seoul, the Kospi climbed 0.7% to 2,626.86.
Australia's S&P/ASX 200 edged 0.1% lower, to 7,399.00 and the SET in Bangkok was up 0.6%. The Sensex in India was little changed.
On Friday, the S&P 500 rose 1% to 4,582.23, closing out its ninth winning week in the last 11. The Dow added 0.5% to 35,459.29 and the Nasdaq climbed 1.9% to 14,316.66 as Big Tech stocks led the market.
Stocks have been rising recently on hopes high inflation is cooling enough to get the Federal Reserve to stop hiking interest rates. That in turn could allow the economy to continue growing and avoid a long-predicted recession.
A report on Friday bolstered those hopes, saying the inflation measure the Fed prefers to use slowed last month by a touch more than expected. Perhaps just as importantly, data also showed that total compensation for workers rose less than expected during the spring. While that's discouraging for workers looking for bigger raises, investors see it adding less upward pressure on inflation.
The hope among traders is that the slowdown in inflation means Wednesday's hike to interest rates on by the Federal Reserve will be the final one of this cycle. The federal funds rate has leaped to a level between 5.25% and 5.50%, up from virtually zero early last year. High interest rates work to lower inflation by slowing the entire economy and hurting prices for stocks and other investments.
Though critics say the stock market’s rally may have gone too far, too fast, hopes for a halt to rate hikes helped technology stocks and others seen as big beneficiaries from easier rates to rally and lead the market Friday.
Microsoft, Apple and Amazon each rose at least 1.4% and were the three strongest forces pushing upward on the S&P 500.
Companies also continued to deliver stronger profits for the spring than analysts expected. Roughly halfway through the earnings season, more companies than usual are topping profit forecasts, according to FactSet.
Intel rose 6.6% after reporting a profit for the latest quarter, when analysts were expecting a loss.
Food giant Mondelez International climbed 3.7% after reporting stronger results for the spring than expected. The company behind Oreo and Ritz also raised its forecasts for financial results for the full year.
In other trading on Monday, U.S. benchmark crude oil gave up 42 cents to $80.16 a barrel in electronic trading on the New York Mercantile Exchange. It gained 49 cents to $80.58 on Friday.
Brent crude, the international standard, shed 47 cents to $83.94 a barrel.
The U.S. dollar rose to 141.87 Japanese yen from Friday's 141.01 yen. The euro slipped to $1.1012 from $1.1019. ___
AP Business Writer Joe McDonald in Beijing contributed. | https://www.springfieldnewssun.com/nation-world/stock-market-today-asia-shares-gain-after-wall-st-rally-as-investors-pin-hopes-on-china-stimulus/RYDALEXP75CZTDY54V5MVJGJ5U/ | 2023-07-31T05:18:23 | 1 | https://www.springfieldnewssun.com/nation-world/stock-market-today-asia-shares-gain-after-wall-st-rally-as-investors-pin-hopes-on-china-stimulus/RYDALEXP75CZTDY54V5MVJGJ5U/ |
ATLANTA (AP) — A Georgia prosecutor is expected to seek a grand jury indictment in the coming weeks in her investigation into efforts by Donald Trump and his allies to overturn the former president's 2020 election loss.
Fulton County District Attorney Fani Willis began investigating more than two years ago, shortly after a recording was released of a January 2021 phone call Trump made to Georgia's secretary of state.
Willis has strongly hinted that any indictment would come between July 31 and August 18. One of two grand juries seated July 11 is expected to hear the case.
If Trump is indicted by a Georgia grand jury, it would add to a growing list of legal troubles as he campaigns for president. Trump is set to go to trial in New York in March to face state charges related to hush-money payments made during the 2016 presidential campaign. And he has another trial scheduled for May on federal charges related to his handling of classified documents. He has pleaded not guilty in those cases.
The Justice Department is also investigating Trump's role in trying to halt the certification of 2020 election results in the run-up to the Jan. 6, 2021, assault on the U.S. Capitol. Trump said he's been told he's a target of that investigation, which likely has some overlap with the one in Georgia.
Details of the Georgia investigation that have become public have fed speculation that Willis is building a case under the Georgia Racketeer Influenced and Corrupt Organizations Act, which would allow her to charge numerous people in a potentially wide-ranging scheme.
Here are six investigative threads Willis and her team have explored:
THE PHONE CALLS
The Georgia investigation was prompted by the Jan. 2, 2021 phone call Trump made to Georgia Secretary of State Brad Raffensperger. Trump suggested the state's top elections official could help "find" the votes needed to put him ahead of Democrat Joe Biden in the state.
“All I want to do is this: I just want to find 11,780 votes, which is one more than we have,” Trump is heard saying on a recording of the call, which was leaked to news outlets. “Because we won the state.”
Trump has insisted he did nothing wrong and has repeatedly said the call was “perfect.”
Trump also called other top state officials in his quest to overturn his 2020 election loss, including Gov. Brian Kemp, then-House Speaker David Ralston, Attorney General Chris Carr and the top investigator in the secretary of state's office.
U.S. Sen. Lindsey Graham, a South Carolina Republican, also called Raffensperger shortly after the November election. Raffensperger said at the time that Graham asked whether he had the power to reject certain absentee ballots, which Raffensperger has said he interpreted as a suggestion to toss out legally cast votes.
Graham has denied wrongdoing, saying he just wanted to learn about the signature verification process.
FAKE ELECTORS
Biden won Georgia by a margin of fewer than 12,000 votes. Just over a month after the election, on Dec. 14, 2020, a group 16 Georgia Democratic electors met in the Senate chamber at the state Capitol to cast the state's Electoral College votes for him. They each marked paper ballots that were counted and confirmed by a voice roll call.
That same day, in a committee meeting room at the Capitol, 16 prominent Georgia Republicans — a lawmaker, activists and party officials — met to sign a certificate falsely stating that Trump had won and declaring themselves the state’s “duly elected and qualified” electors. They sent that certificate to the National Archives and the U.S. Senate.
Georgia was one of seven battleground states that Trump lost where Republican fake electors signed and submitted similar certificates. Trump allies in the U.S. House and Senate used those certificates to argue for delaying or blocking the certification of the election during a joint session of Congress.
Prosecutors in Fulton County have said in court filings that they believe Trump associates worked with state Republicans to coordinate and execute the plan.
The multi-state effort was ultimately unsuccessful. Despite public pressure from Trump and his supporters, then-Vice President Mike Pence refused on Jan. 6, 2021, to introduce the unofficial pro-Trump electors. After the attack on the U.S. Capitol put a violent halt to the certification process, lawmakers certified Biden's win in the early hours of Jan. 7, 2021.
At least eight of the fake electors have since reached immunity deals with Willis' team. And a judge last summer barred Willis from prosecuting another one, Lt. Gov. Burt Jones, because of a conflict of interest.
FALSE CLAIMS OF ELECTION FRAUD
Republican state lawmakers held several hearings at the Georgia Capitol in December 2020 to examine alleged problems with the November election. During those meetings, former New York mayor Rudy Giuliani and other Trump allies made unproven claims of widespread election fraud.
They alleged that election workers tallying absentee ballots at State Farm Arena in Atlanta had told outside observers to leave and then pulled out “suitcases” of unlawful ballots and began scanning them. The Trump allies played clips of surveillance video from the arena to support their allegations. State and federal officials investigated and said there was no evidence of election fraud at the site.
Some Trump allies also said thousands of people who were ineligible — including people convicted of felonies, people under the age of 18, people who had voted in another state — had cast votes in Georgia. The secretary of state's office has debunked those claims.
ALLEGED ATTEMPTS TO PRESSURE ELECTION WORKER
Two of the election workers seen in the State Farm Arena surveillance video, Ruby Freeman and her daughter Wandrea "Shaye" Moss, said they faced relentless harassment online and in person as a result of the allegations made by Trump and his allies.
Giuliani last week conceded that statements he made about the two election workers were false.
In a bizarre episode detailed by prosecutors in court filings, a woman traveled from Chicago to Georgia and met with Freeman on Jan. 4, 2021. The woman initially said she wanted to help Freeman but then warned that Freeman could go to prison and tried to pressure her into falsely confessing to committing election fraud, prosecutors wrote in court filings last year.
ELECTION EQUIPMENT ACCESSED
Trump-allied lawyer Sidney Powell and others hired a computer forensics team to copy data and software on election equipment in Coffee County, some 200 miles southeast of Atlanta, according to invoices, emails, security video and deposition testimony produced in response to subpoenas in a long-running lawsuit.
The county Republican Party chair at the time — who also served as a fake elector — greeted them when they arrived at the local elections office on Jan. 7, 2021, and some county elections officials were also on hand during the daylong visit. The secretary of state's office has said this amounted to “alleged unauthorized access” of election equipment and the Georgia Bureau of Investigation is looking into it at the secretary of state's request.
Two other men who have been active in efforts to question the 2020 election results also visited Coffee County later that month and spent hours inside.
U.S. ATTORNEY RESIGNATION
U.S. Attorney BJay Pak, the top federal prosecutor in Atlanta, abruptly resigned two days after Trump called Raffensperger and a day after a recording of that call was made public. During that conversation, Trump called Pak a "never-Trumper," implying that he didn't support the president.
In December 2020, then-U.S. Attorney General William Barr asked Pak to investigate allegations by Giuliani and other Trump allies of widespread election fraud. Pak, who had been appointed by Trump in 2017, reported back that he had found no evidence of such fraud.
In August 2021, Pak told the U.S. Senate Judiciary Committee, which was investigating Trump's post-election actions, that he resigned on Jan. 4, 2021, after learning from Department of Justice officials that Trump did not believe enough was being done to investigate allegations of election fraud and wanted him gone as U.S. attorney.
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MINNEAPOLIS (AP) — The Minnesota Vikings have given outside linebacker Danielle Hunter a hefty pay raise, paving the way for the team's best pass rusher to participate in practice after a months-long contract stalemate.
The Vikings announced Sunday on their website that they reached a new deal with Hunter, the three-time Pro Bowl pick with 71 sacks who will turn 29 in three months.
Hunter reported to training camp last week on schedule after skipping the offseason program and mandatory minicamp, but he has yet to join his teammates on the field. Head coach Kevin O'Connell said Saturday that Hunter has been “in the building” and that they've been in “daily dialogue” about his physical and mental preparation.
“Danielle Hunter is a very special player, and as soon as we can get him out here, you guys will see him out here,” O'Connell said.
Hunter's previous contract called for a $4.9 million base salary. According to NFL Network, he'll make $17 million guaranteed this year with an opportunity to earn an additional $3 million in incentives. Hunter will still hit the free agent market after the season, unless he and the team strike a deal on an extension in the meantime.
Hunter's presence will be vital for a Vikings defense that has been one of the NFL's worst over the past three years. They allowed the second-most yards and the fourth-most points in the league in 2022, despite decent production by their primary edge rushers. Hunter had 10 1/2 sacks, Za'Darius Smith had 10 sacks and backups D.J. Wonnum and Patrick Jones had four sacks apiece.
Smith was since traded to Cleveland in a cost-cutting move, leaving Hunter as the only proven pass rusher on the roster. Marcus Davenport was signed as a free agent to push for a starting spot, but this remains one of the biggest questions surrounding the team this season.
“I think Danielle’s a phenomenal player,” said defensive coordinator Brian Flores, who was hired to replace the fired Ed Donatell. “I look forward to working with him.”
Under Donatell, Hunter often found himself as a standup rusher in a three-point stance. The Vikings with Flores are aiming to get back to turning Hunter loose with his hand in the ground more often.
“Veteran players, they’ve seen a lot of defense, coverages, fronts, stunts. I think terminology will probably be the one thing that’s a little bit different, maybe, but some of it, there’s some crossover from some things he’s heard in the past so I don’t think it’ll take long for him to get up to speed," Flores said. “At the end of the day, we’re telling him to go get the quarterback. There’s really not much to that. So I think he’ll be just fine.”
___
AP NFL: https://apnews.com/hub/NFL and https://twitter.com/AP_NFL | https://www.springfieldnewssun.com/nation-world/vikings-end-stalemate-with-danielle-hunter-by-giving-edge-rusher-a-big-pay-raise/TW5F3AW5VVG7DDRF2TSPY5YBMY/ | 2023-07-31T05:18:37 | 0 | https://www.springfieldnewssun.com/nation-world/vikings-end-stalemate-with-danielle-hunter-by-giving-edge-rusher-a-big-pay-raise/TW5F3AW5VVG7DDRF2TSPY5YBMY/ |
“Guardians of the Galaxy Vol. 3,” “The Lost Flowers of Alice Hunt” with Sigourney Weaver and Quavo's album “Rocket Power” are among the new television, movies, music and games headed to a device near you
Among the offerings worth your time as selected by The Associated Press' entertainment journalists are "Mixtape," a Paramount+ documentary celebrating hip-hop, and the return of the acclaimed comedy "Reservation Dogs" for its third and final season on FX on Hulu.
NEW MOVIES TO STREAM
— James Gunn's "Guardians of the Galaxy" reaches an appropriately sincere, satirical and cornball finale in "Guardians of the Galaxy Vol. 3." The film, one of the few non-"Barbie" or "Oppenheimer" summer hits, arrives Wednesday on Disney+ having already grossed $844 million in worldwide ticket sales. Gunn's underdog superhero trilogy culminates with a tale focused on a backstory for Rocket, Bradley Cooper's wise-cracking raccoon, and a showdown with a supervillain (Chukwudi Iwuji) hellbent on repopulating Earth with a "perfect" species. In my review, I praised the conviction of Gunn's soupy sci-fi spectacle, writing: "Whatever this sweet, surreal sci-fi shamble is that Gunn has created, everyone here seems to believe ardently in it."
— "Oppenheimer" isn't the only movie around returning to Los Alamos. Steve James, the acclaimed documentarian of "Hoop Dreams," in "A Compassionate Spy" details the story of physicist Ted Hall, a brilliant 18-year-old Harvard student when he was recruited to work on the Manhattan Project and went on to pass nuclear information to the Soviets. He confessed in 1998, a year before his death. Hall, one of several scientists to leak information from the atom bomb project, maintained he did it for the good of humanity and to prevent a nuclear monopoly. "A Compassionate Spy" debuts Friday, Aug. 4 on video-on-demand and in theaters.
— "Turn Every Page: The Adventures of Robert Caro and Robert Gottlieb," a documentary of the decades-long collaboration between the "Power Broker" author and his revered editor is a stirring and affection portrait of two literary giants. The film, directed by the editor's daughter, Lizzie Gottlieb, will begin streaming Tuesday on the Criterion Channel, just weeks after the death of Gottlieb, who edited novels by Toni Morrison, John Cheever, Joseph Heller and many others. In my review of the film, I wrote: "Civil wars over semicolons and heated debate over the word 'looms' would not, on the face of it, seem like the stuff of a gripping big-screen movie. But make no mistake about it, 'Turn Every Page'... is as much a rock 'em, sock 'em clash of heavyweights as found in any blockbuster."
NEW MUSIC TO STREAM
— Quavo will release "Rocket Power," his first album since fellow Migos member Takeoff was shot and killed outside a bowling alley in November 2022. Quavo introduced the new LP with a trailer that features a massive CGI rocket preparing to launch into space. In a statement, he shared: "Through the process of healing I've learned to turn tragedy into triumph. I had to dig deep into my purpose and find the power to keep striving." This summer, Quavo and Future shared a new song, "Turn Your Clic Up," which followed recent singles "Greatness" and "Honey Bun." Shortly before his death, Quavo and Takeoff had shared their joint LP, "Only Built for Infinity Links."
— Rick Springfield, whose hits include "Human Touch," and, of course, "Jessie's Girl," is putting out his 21st album, "Automatic." Written and produced by Springfield, the collection features 20 new songs. "My goal was solid three-minute tunes with the biggest hooks I could come up with," he said in a news release. Springfield previewed his sound by releasing the title track and "She Walks With the Angels." The album is dedicated to Matty Spindel, a friend and soundman of 25 years who died in 2022. Springfield will be hitting the road this summer on the I Want My '80s Tour.
— AP Entertainment Writer Mark Kennedy
NEW SERIES TO STREAM
— Hip-hop is markings its 50th anniversary and Paramount+ will stream a documentary called "Mixtape" beginning Tuesday. The film explores how before the hip-hop genre had radio play, streaming or social media, its songs were often shared via mixtapes. Lil Wayne, DJ Khaled, Fat Joe, 2 Chainz, Big Boi and KRS-One are just a few of the artists featured in the doc about mixtape culture.
— The half-hour critically acclaimed comedy "Reservation Dogs" returns for its third and final season on Wednesday on FX on Hulu. The series follows four Indigenous teens who, when we first meet them in season one, are reeling from the death of their friend Daniel. Daniel's dream was to leave rural Oklahoma for California. The group decides the best way to honor Daniel is by fulfilling his goal and traveling to this magical state he was enamored with. To get there, they'll steal and scheme but it's not an easy road. In this new season, they've made it to California but don't have the means to return home. Now that the friends have achieved Daniel's wish, they also must decide what to do next with their own lives. The Indigenous representation in "Reservation Dogs" also extends behind-the-camera with each of its writers, directors and crew.
— Netflix's popular British rom-com drama series "Heartstopper," starring Joe Locke and Kit Connor returns for its second season on Wednesday. Locke and Connor play Charlie and Nick, two high school schoolmates who fell in love in season one. The series has been praised for its portrayal of LGTBQ+ characters.
— Sigourney Weaver and Alycia Debnam-Carey co-star in "The Lost Flowers of Alice Hunt" for Prime Video. The story is based on a novel of the same name by Holly Ringland. Debnam-Carey plays Alice, who as a young girl, moved in with her grandmother June – played by Weaver – after a family tragedy. June is a flower farmer and teaches Alice how flowers can be used as a form of self-expression. The story spans two decades and follows Alice into adulthood. The series debuts Friday, Aug. 4 on the streamer.
NEW VIDEO GAMES TO PLAY
— Dungeons & Dragons has seen a boom in popularity over the last few years, with a hit movie, live-streamed games and a major supporting role on "Stranger Things." But it's been a while since we've gotten a true D&D video game. That drought ends with Baldur's Gate 3. You begin as just some poor sap with an evil parasite stuck in your brain, but once you round up the typical gang of wizards, brawlers, clerics and rogues, the fate of D&D's sprawling Forgotten Realms is in your hands. Developer Larian Studios, best known for the terrific Divinity: Original Sin, has shown it has the chops to create stirring role-playing adventures, and has promised that this one could take up to 200 hours to fully explore. You can pick up your sword or wand Thursday on PC, or hold out for the PlayStation 5 version in September.
___
Catch up on AP's entertainment coverage here: https://apnews.com/entertainment.
Credit: Chris Pizzello/Invision/AP
Credit: Chris Pizzello/Invision/AP
Credit: Amy Harris/Invision/AP
Credit: Amy Harris/Invision/AP | https://www.springfieldnewssun.com/nation-world/what-to-stream-this-week-guardians-of-the-galaxy-vol-3-quavo-reservation-dogs-and-mixtape/VUTTPVEW3ZFRFNKAV62BC4EXQA/ | 2023-07-31T05:18:44 | 0 | https://www.springfieldnewssun.com/nation-world/what-to-stream-this-week-guardians-of-the-galaxy-vol-3-quavo-reservation-dogs-and-mixtape/VUTTPVEW3ZFRFNKAV62BC4EXQA/ |
High pressure in the region begins this week and will lead to drier conditions with seasonable temperatures until Wednesday, according to the National Weather Service in Wilmington.
Today will be sunny and warm with a high near 84 degrees. Overnight, expect mostly clear skies with a low around 59 degrees.
Tuesday will be bright sunshine and warm temps with highs in the mid-80s, followed by a partly cloudy night with a low of 60 degrees.
Highs will be in the mid-80s for Wednesday along with mostly sunny skies, followed by a 40% chance of showers and storms overnight. Despite the small chance of rain, it’ll be mostly cloudy and cool with a low of 64 degrees.
More humid airmass will return toward the end of the workweek, bringing with it renewed chances for showers and storms, according to the NWS.
Thursday has a 50% chance of precipitation along with thunderstorms but otherwise will be partly sunny throughout the day. The high will be near 84 degrees.
Thursday night has a chance of showers and storms with a mostly cloudy forecast expected. The low will be around 69 degrees.
Rain is possible Friday with dry conditions and sunny skies returning for the weekend.
About the Author | https://www.springfieldnewssun.com/weather/sunny-skies-sunny-days-ahead-today-and-this-week/EHPTRZD67BESVPNEPKDGCIJZAY/ | 2023-07-31T05:18:50 | 1 | https://www.springfieldnewssun.com/weather/sunny-skies-sunny-days-ahead-today-and-this-week/EHPTRZD67BESVPNEPKDGCIJZAY/ |
CASCO, Maine — One person is in custody after a police incident in Casco Sunday night.
An official with the Cumberland County Sheriff's Office said no one was injured during the incident that happened near the Point Sebago Resort.
Maine State Police and other agencies also responded to the scene Sunday. Officials cleared the area late Sunday night.
This story will be updated when more information becomes available. | https://www.newscentermaine.com/article/news/crime/one-suspect-taken-into-custody-after-a-police-incident-in-casco/97-5d960dd9-7087-4429-9a89-06101bc7f28d | 2023-07-31T05:19:33 | 1 | https://www.newscentermaine.com/article/news/crime/one-suspect-taken-into-custody-after-a-police-incident-in-casco/97-5d960dd9-7087-4429-9a89-06101bc7f28d |
Erratic winds challenge firefighters battling two major California blazes
MOJAVE NATIONAL PRESERVE, Calif. (AP) — A massive wildfire burning out of control in California’s Mojave National Preserve was spreading rapidly amid erratic winds, while firefighters reported progress against another major blaze to the southwest that prompted evacuations.
The York Fire that erupted Friday near the remote Caruthers Canyon area of the vast wildland preserve crossed the state line into Nevada on Sunday and sent smoke further east into the Las Vegas Valley.
Wind-driven flames 20 feet (6 meters) high in some spots charred more than 110 square miles (284 square kilometers) of desert scrub, juniper and Joshua tree woodland, according to an incident update. There was zero containment.
“The dry fuel acts as a ready ignition source, and when paired with those weather conditions it resulted in long-distance fire run and high flames, leading to extreme fire behavior,” the update said. No structures were threatened.
To the southwest, the Bonny Fire was holding steady at about 3.4 square miles (8.8 square kilometers) in rugged hills of Riverside County. More than 1,300 people were ordered to evacuate their homes Saturday near the community of Aguanga that is home to horse ranches and wineries.
Gusty winds and the chance of thunderstorms into Monday will heighten the risk of renewed growth, the California Department of Forestry and Fire Protection said in a statement.
One firefighter was injured in the blaze, which was 5% contained.
Copyright 2023 The Associated Press. All rights reserved. | https://www.kxii.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ | 2023-07-31T05:20:11 | 0 | https://www.kxii.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ |
Tennessee Sports Hall of Fame awards 1958 Oak Ridge football team
Local events planned Aug. 18 at Wildcats' first football game
Even after 65 years, the accolades keep coming for the 1958 Oak Ridge High School football team.
On Saturday night, July 22, the Tennessee Sports Hall of Fame honored the Wildcats with the prestigious 2023 David Williams Significant Historical Achievement Award. The presentation was made before a sell-out crowd of more than 800 people at the Hall of Fame’s annual Induction Award Banquet at Nashville’s Omni Hotel.
While introducing the team, the most historic achievement noted by Mike Keith, voice of the Tennessee Titans and host for the banquet, included that the 1958 Wildcats were the first team in Tennessee high school football history to win a mythical national championship. He also cited the phenomenal success of the players later in life, citing careers in the areas of nuclear physics, architecture, and professions such as doctors, engineers, educators, entrepreneurs, and business owners.
He also noted that one team member served as science and technology advisor to two U.S. presidents and chaired the committee that transformed portions of some obscure internal government communication systems into what eventually became known as the Internet.
Forty-seven players were on the 1958 team led by coaching legends Jack Armstong and Don Bordinger. Seven of the original members attended the Hall of Fame awards banquet. They included Woody Barwick, Mike Brady, Skip Brinkman, Jimmie Culp, Howard Dunnebacke, Sam Owen, and Larry Richards. With other family and friends there to support them, the Oak Ridge team was well represented with more than 60 attendees from throughout the United States.
The honoree award comes 65 years after the team was the first Tennessee high school football team to be selected as national champions. The team led the state in offense and defense and had 16 players play college football, seven of which played Southeastern Conference teams.
Joe Gaddis, Oak Ridge High School athletic director, and Mike Brady, captain of the 1958 Oak Ridge Wildcat team, accepted the award on behalf of the entire team. Phillip Fulmer, former University of Tennessee head coach and athletic director, presented the award. Per Gaddis, the commemorative award cup will soon be on permanent display at an appropriate place of honor within the trophy area adjacent to the high school gym.
'58 ORHS team to be honored Aug. 18 in Oak Ridge
Area sports fans will get another chance to show their appreciation for the 1958 team’s accomplishments on Aug. 18. Members of the 1958 national championship team will be guests at a pre-game tailgate party prior to the opening game of the Oak Ridge Wildcats 2023 season and will be recognized on Blankenship Field either prior to kick-off or at half-time. Organizers of the Aug. 18 activities have had difficulty contacting many team members, especially those who were juniors and sophomores at the time and ask the public’s help in making sure all members of the 1958 team and their families are notified. | https://www.oakridger.com/story/news/local/2023/07/30/1958-oak-ridge-high-football-team-honored-by-state-sports-hall-of-fame/70477089007/ | 2023-07-31T05:20:30 | 1 | https://www.oakridger.com/story/news/local/2023/07/30/1958-oak-ridge-high-football-team-honored-by-state-sports-hall-of-fame/70477089007/ |
Dear Abby: Parents make surprising choice following divorce
Dear Abby: I am 49 and have been divorced for 20 years. When we first separated, my ex moved in with my parents while I struggled to raise my four kids. He stayed there for seven years. He moved out until a year and a half ago. Again, my parents have allowed him back in!
While I understand that they shouldn’t have had to cease contact because of the divorce, I don’t feel it’s right for him to be living there. This has caused an ongoing rift between my family and me because I have let them know that it hurts me.
My parents pretty much told me my feelings don’t matter. I was homeless living in my car for a few weeks while it was bitter cold and snowing. But I’m not supposed to be upset that he’s nice and warm, eating prepared meals, showering and using their vehicles for next to nothing? He has had a full-time job for 10 years.
I feel my parents are disrespectful, hurtful and rude toward me. What are your thoughts about what I should do or how to handle this?
— Perturbed in Pennsylvania
Dear Perturbed: My thought is that when you and your ex-husband divorced, your parents sided with him, and you have every right to your feelings. Being told that your feelings do not matter had to have been devastating.
The way to handle this would be to stay as far from your parents as possible and figure out how to have a rewarding life on your own. Take that path — and spend as little time as possible looking backward because you really have no other choice. Success would be the best revenge.
Dear Abby: I’m 26, and I have never been in a long-term relationship. I have used dating apps and have dated several times, but nothing seems to stick after the third one. This year, I have put myself out there more by going to Meetup groups and to religious services.
When I browse Instagram or Facebook, I see content that makes me feel guilty and disappointed. It’s depressing to see people I know getting engaged or married. When I was in high school, most of my classmates went to prom, while I stayed at home.
I’m beginning to wonder if I’ll never find a good quality life partner or if I’m meant to be single forever. I’m afraid there may be something wrong with me. What can I do to move forward?
— Uncoupled in Minnesota
Dear Uncoupled: You may be focusing too much on your goal and not enough on enjoying the experience. Dating is a sifting process. It can be tedious and depressing, and it doesn’t always result in meeting Prince Charming. Because you haven’t yet met The One doesn’t mean the alternative is winding up in a convent. Move forward by teaching yourself to enjoy the present, and you may find you have better luck.
Contact Dear Abby at www.DearAbby.com. | https://www.detroitnews.com/story/life/advice/2023/07/31/dear-abby-parents-make-surprising-choice-following-divorce/70485829007/ | 2023-07-31T05:20:31 | 1 | https://www.detroitnews.com/story/life/advice/2023/07/31/dear-abby-parents-make-surprising-choice-following-divorce/70485829007/ |
Dr. Roach: Spinal cord injury gets misdiagnosed as ‘blood pressure stroke’
Dear Dr. Roach: Have you ever heard of a “low blood pressure stroke”? That was my husband’s (incorrect) diagnosis several years back when he suddenly could not move his arms and legs. He was told that not enough oxygen was getting to his spine. (His blood pressure is historically low, usually around 90/60.)
That lasted about seven months, and he was bedridden the entire time. He then went to a neurosurgeon and was (correctly) diagnosed with a spinal cord injury. He had C1-C2 surgery and had use of his limbs the next day. After months of physical therapy, he regained a lot of function.
We’ve never heard of that diagnosis before or after his experience. Does it really exist?
— E.S.K.
Dear E.S.K.: The brain has tremendous ability to regulate its own blood flow under a very wide range of blood pressures, but there are some limits. When a person is used to very high blood pressure levels, such as 200/110 for months or years, a sudden drop to 90/60 (or even 120/80, sometimes) can cause a stroke. That’s the main reason we don’t lower blood pressure very quickly in people who have had very high blood pressure levels for a long time. It takes weeks or months for the brain to recover its ability to regulate blood flow.
In a person who has a heart attack, the prolonged low blood pressure (or no blood pressure) will also cause brain damage. That’s why starting CPR as quickly as possible is so critical in order to preserve brain function.
In both of these cases, not enough blood is getting to the central nervous system (the brain, the spinal cord and the retinas), which can lead to cell death — the hallmark of a stroke. But these are extreme cases.
A healthy person whose normal blood pressure is around 90/60 is at risk for fainting when suddenly standing; however, they are at a lower-than-average risk for heart disease and stroke. The diagnosis of “a low blood pressure stroke” for your husband doesn’t make any sense at all to me, and advanced imaging of the brain should have made it abundantly clear that it was not the right diagnosis.
I’m shocked that he wasn’t treated correctly for such a long time. But I’m very happy to hear that his neurosurgeon did not assume the diagnosis of a stroke, and instead made the correct diagnosis and performed the procedure to help him recover. Your husband is fortunate that he still had neurological function to recover after such a long time, since spinal cord injuries generally do better when treated promptly.
Dear Dr. Roach: My primary care physician and blood specialist say there is nothing that will increase white blood cell count. Are there supplements that I can take or foods to eat to improve the low count?
— R.J.L.
R.J.L.: The question is, why is your white blood cell count low? Some people have low white blood cell counts for no reason; it runs in families, so there aren’t any health concerns there. However, there are a large variety of blood diseases that cause low white cell counts. Some affect the lymphocytes, while others affect the granulocytes (the two main types of white cells).
Nutritional deficiencies are extremely rare in North America (vitamin B12, folic acid and copper are the exceptions that should be looked for), so neither diet nor supplements are usually helpful. In absence of blood disease or symptoms, low white blood cell counts usually do not need treatment.
Readers may email questions to ToYourGoodHealth@med.cornell.edu. | https://www.detroitnews.com/story/life/advice/2023/07/31/dr-roach-spinal-cord-injury-gets-misdiagnosed-as-blood-pressure-stroke/70489489007/ | 2023-07-31T05:20:37 | 1 | https://www.detroitnews.com/story/life/advice/2023/07/31/dr-roach-spinal-cord-injury-gets-misdiagnosed-as-blood-pressure-stroke/70489489007/ |
Pontiac doctor convicted in medical fraud scheme tied to citizenship
A Pontiac doctor has been convicted of committing medical fraud to help immigrants obtain U.S. citizenship.
Dr. Muhammad Awaisi, 64, was found guilty of five charges related to the fraud, said federal officials. A federal jury rendered the verdict last week after a four-day trial in U.S. District Court in Detroit.
Awaisi, who is facing up to 35 years in prison, is scheduled to be sentenced on Dec. 4.
Neither he or his attorney, Steven Haney of Eastpointe, were immediately available for comment.
Awaisi conspired with Firoza Van Horn, a psychologist from Bloomfield Hills, to create fraudulent medical documents, said prosecutors. Van Horn has pleaded guilty to conspiracy and is awaiting sentencing.
The fraudulent documents were designed to be used by citizen applicants seeking medical waivers of requirements that they pass a citizenship test and demonstrate a knowledge of the English language, said authorities.
As part of the scheme, Awaisi conducted sham medical examinations that falsely diagnosed citizen applicants with a variety of medical ailments, said prosecutors. He also wrote prescriptions for opioids and other controlled substances that were unnecessary, they said.
He was convicted of one count of conspiring to commit an offense against the United States and to defraud the United States, two counts of attempted procurement of naturalization contrary to law, and two counts of making and using a false document.
U.S. Attorney Dawn Ison said his actions were a slap in the face to immigrants who tried to obtain U.S. citizenship the proper way.
"Dr. Awaisi's fraud is an affront to all those honest immigrants as well as to his most basic ethical requirements as a physician," she said.
The FBI, which handled the case, said Awaisi showed a total disregard for the oath he took as a physician.
"The alleged fraud, scheming and conspiracy in this case is overwhelming," said Devin Kowalski, acting special agent in charge of the FBI office in Detroit. | https://www.detroitnews.com/story/news/local/oakland-county/2023/07/30/pontiac-doctor-muhammad-awaisi-convicted-medical-fraud-scheme-tied-to-citizenship/70495609007/ | 2023-07-31T05:20:43 | 1 | https://www.detroitnews.com/story/news/local/oakland-county/2023/07/30/pontiac-doctor-muhammad-awaisi-convicted-medical-fraud-scheme-tied-to-citizenship/70495609007/ |
HONG KONG, July 31, 2023 /PRNewswire/ -- Akeso Inc. ("Akeso", the "Company"; 9926.HK), a commercial-stage biopharmaceutical company focused on developing and commercializing first-in-class and best-in-class innovative medicines globally, today announced that it is expected that the Company will record a profit of not less than RMB2.3 billion for the six months ended June 30, 2023. This is the first time for the Company to achieve half-year profits.
The turnaround from loss to profit during the Reporting Period was mainly attributable to:
- In respect of Ivonescimab (AK112, PD-1/VEGF) independently developed by the Company, the Company has entered into the collaborative and licensing agreement with Summit Therapeutics (details of which are set out in the announcement of the Company dated December 6, 2022). The Company has received the total upfront payment equivalent to US$500 million in full during the first quarter of 2023 (details of which are set out in the announcements of the Company dated January 26, 2023 and March 6, 2023). Part of such upfront payment was recognized as licensing fee income which significantly contributed to the revenue of the Company for the Reporting Period, and amounted to approximately RMB2.9 billion. The revenue recognition of the remaining portion of the upfront payment will be recognized as revenue in batches going forward.
- In respect of the Company's innovative product 开坦尼® (cadonilimab, PD-1/CTLA-4), since its launch in June 2022, it has recorded significant increase of the patients as well as product sales, which reflects the excellent clinical value of cadonilimab. In addition, 安尼可®(penpulimab, PD-1) also continued to contribute to the growth in the Company's product sales revenue during the Reporting Period.
- The Company has continued to optimise its cost management capabilities in a scientific and efficient way and has achieved better results in cost control while accelerating innovative products development and pipelines advancement.
About Akeso
Akeso (HKEX: 09926) is a commercial-stage biopharmaceutical company committed to the discovery, development, manufacturing, and commercialization of innovative medicines with high unmet medical needs worldwide. Founded in 2012, the Company has established a comprehensive in-house drug development platform (ACE Platform) and know-how, including R&D, clinical development, CMC (Chemistry, Manufacturing, and Controls), and commercialization capabilities.
With fully integrated multi-functional platform, Akeso is internally working on a robust pipeline of over 30 innovative assets in the fields of cancer, autoimmune disease, inflammation, metabolic disease, and other major therapeutic areas. 19 assets have entered clinical stage. Leveraging in-house developed bispecific platform technology ("Tetrabody technology"), the Company has advanced four potential first-in-class bispecific antibody drugs into market or clinical development, including cadonilimab (PD-1/CTLA-4), ivonescimab (PD-1/VEGF), PD-1/LAG-3, TIGIT/TGF-Beta bispecific antibodies. In June 2022, cadonilimab was approved by the NMPA and became the first commercialized PD-1 based bispecific drug globally. Another Akeso internally discovered and developed oncology product, penpulimab (a PD-1 antibody), was granted marketing approval in China in August 2021. In December 2022, the Company out-licensed breakthrough bispecific antibody, ivonescimab (PD-1/VEGF bi-specific antibody, AK112), with up to US$5 Billion total potential deal value to Summit Therapeutics for development and commercialization in the U.S., Canada, Europe, and Japan.
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SOURCE Akeso, Inc. | https://www.kalb.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ | 2023-07-31T05:21:31 | 0 | https://www.kalb.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ |
HONG KONG, July 31, 2023 /PRNewswire/ -- Akeso Inc. ("Akeso", the "Company"; 9926.HK), a commercial-stage biopharmaceutical company focused on developing and commercializing first-in-class and best-in-class innovative medicines globally, today announced that it is expected that the Company will record a profit of not less than RMB2.3 billion for the six months ended June 30, 2023. This is the first time for the Company to achieve half-year profits.
The turnaround from loss to profit during the Reporting Period was mainly attributable to:
- In respect of Ivonescimab (AK112, PD-1/VEGF) independently developed by the Company, the Company has entered into the collaborative and licensing agreement with Summit Therapeutics (details of which are set out in the announcement of the Company dated December 6, 2022). The Company has received the total upfront payment equivalent to US$500 million in full during the first quarter of 2023 (details of which are set out in the announcements of the Company dated January 26, 2023 and March 6, 2023). Part of such upfront payment was recognized as licensing fee income which significantly contributed to the revenue of the Company for the Reporting Period, and amounted to approximately RMB2.9 billion. The revenue recognition of the remaining portion of the upfront payment will be recognized as revenue in batches going forward.
- In respect of the Company's innovative product 开坦尼® (cadonilimab, PD-1/CTLA-4), since its launch in June 2022, it has recorded significant increase of the patients as well as product sales, which reflects the excellent clinical value of cadonilimab. In addition, 安尼可®(penpulimab, PD-1) also continued to contribute to the growth in the Company's product sales revenue during the Reporting Period.
- The Company has continued to optimise its cost management capabilities in a scientific and efficient way and has achieved better results in cost control while accelerating innovative products development and pipelines advancement.
About Akeso
Akeso (HKEX: 09926) is a commercial-stage biopharmaceutical company committed to the discovery, development, manufacturing, and commercialization of innovative medicines with high unmet medical needs worldwide. Founded in 2012, the Company has established a comprehensive in-house drug development platform (ACE Platform) and know-how, including R&D, clinical development, CMC (Chemistry, Manufacturing, and Controls), and commercialization capabilities.
With fully integrated multi-functional platform, Akeso is internally working on a robust pipeline of over 30 innovative assets in the fields of cancer, autoimmune disease, inflammation, metabolic disease, and other major therapeutic areas. 19 assets have entered clinical stage. Leveraging in-house developed bispecific platform technology ("Tetrabody technology"), the Company has advanced four potential first-in-class bispecific antibody drugs into market or clinical development, including cadonilimab (PD-1/CTLA-4), ivonescimab (PD-1/VEGF), PD-1/LAG-3, TIGIT/TGF-Beta bispecific antibodies. In June 2022, cadonilimab was approved by the NMPA and became the first commercialized PD-1 based bispecific drug globally. Another Akeso internally discovered and developed oncology product, penpulimab (a PD-1 antibody), was granted marketing approval in China in August 2021. In December 2022, the Company out-licensed breakthrough bispecific antibody, ivonescimab (PD-1/VEGF bi-specific antibody, AK112), with up to US$5 Billion total potential deal value to Summit Therapeutics for development and commercialization in the U.S., Canada, Europe, and Japan.
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SOURCE Akeso, Inc. | https://www.kbtx.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ | 2023-07-31T05:21:33 | 0 | https://www.kbtx.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ |
SEOUL, South Korea, July 31, 2023 /PRNewswire/ -- J INTS BIO announced the successful dosing of the first patient in its global multi-center Phase 1/2 clinical study of 'JIN-A02' on 31st July at Severance Hospital, Seoul, Korea.
More clinical sites will follow suit, including seven more hospitals in Korea (National Cancer Center, Chungbuk National University Hospital, Samsung Seoul Hospital, Seoul National University Hospital, Seoul St. Mary's Hospital, St. Vincent Hospital, Asan Medical Center), two in the United States, and one in Thailand.
This global phase 1/2 clinical trial seeks to evaluate the safety, pharmacokinetics and anti-tumor activity of "JIN-A02" in advanced NSCLC patients carrying EGFR mutations.
'JIN-A02' is a novel orally administered 4th Generation EGFR TKI, which is highly selective for and strongly inhibits NSCLC with C797S double or triple mutations, showing efficacy even against intracranial tumors by exhibiting high blood-brain barrier penetrance.
Anna Jo, CEO of J INTS BIO, said, "We expect the positive results of 'JIN-A02' in the pre-clinical studies to translate to positive outcomes for patients in the clinical trial" adding that, "We hope also to proceed with the application for designation of orphan drug, and thereby quickly occupy the global NSCLC therapy market through conditional use."
About J INTS BIO
J INTS BIO is a bio company specialized in developing innovative anti-cancer and orphan drugs to realize the goal of changing lives and improving health for patients around the world. J INTS BIO's teams have prior multi-year experience in multinational pharmaceutical companies and CROs and track records in medical, regulatory affairs, drug discovery and development.
About 'JIN-A02'
'JIN-A02' is a novel orally administered 4th Generation EGFR TKI targeting C797S mutations in NSCLC. Although 1st, 2nd, and 3rd Generation EGFR TKIs have been used with some success, recurrence occurs in most patients including those on 3rd Generation TKIs such as Osimertinib. Currently, there are no approved therapies for patients who developed EGFR C797S mutations due to the use of 3rd Generation EGFR TKIs and with the high propensity of these cancers to metastasize to the brain, there is an urgent need to develop an effective drug with high blood-brain barrier permeability as well. 'JIN-A02', a novel oral EGFR TKI, which is effective against C797S double and triple mutations and have a high brain penetrance, is therefore expected to become the most promising Best-in-Class 4th-generation EGFR TKI in NSCLC patients with limited or no viable treatment options.
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SOURCE J INTS BIO | https://www.kalb.com/prnewswire/2023/07/31/j-ints-bio-novel-oral-4th-generation-egfr-tki-jin-a02-dosing-first-patient-global-multi-center-phase-12-clinical-study-began/ | 2023-07-31T05:21:37 | 1 | https://www.kalb.com/prnewswire/2023/07/31/j-ints-bio-novel-oral-4th-generation-egfr-tki-jin-a02-dosing-first-patient-global-multi-center-phase-12-clinical-study-began/ |
SEOUL, South Korea, July 31, 2023 /PRNewswire/ -- J INTS BIO announced the successful dosing of the first patient in its global multi-center Phase 1/2 clinical study of 'JIN-A02' on 31st July at Severance Hospital, Seoul, Korea.
More clinical sites will follow suit, including seven more hospitals in Korea (National Cancer Center, Chungbuk National University Hospital, Samsung Seoul Hospital, Seoul National University Hospital, Seoul St. Mary's Hospital, St. Vincent Hospital, Asan Medical Center), two in the United States, and one in Thailand.
This global phase 1/2 clinical trial seeks to evaluate the safety, pharmacokinetics and anti-tumor activity of "JIN-A02" in advanced NSCLC patients carrying EGFR mutations.
'JIN-A02' is a novel orally administered 4th Generation EGFR TKI, which is highly selective for and strongly inhibits NSCLC with C797S double or triple mutations, showing efficacy even against intracranial tumors by exhibiting high blood-brain barrier penetrance.
Anna Jo, CEO of J INTS BIO, said, "We expect the positive results of 'JIN-A02' in the pre-clinical studies to translate to positive outcomes for patients in the clinical trial" adding that, "We hope also to proceed with the application for designation of orphan drug, and thereby quickly occupy the global NSCLC therapy market through conditional use."
About J INTS BIO
J INTS BIO is a bio company specialized in developing innovative anti-cancer and orphan drugs to realize the goal of changing lives and improving health for patients around the world. J INTS BIO's teams have prior multi-year experience in multinational pharmaceutical companies and CROs and track records in medical, regulatory affairs, drug discovery and development.
About 'JIN-A02'
'JIN-A02' is a novel orally administered 4th Generation EGFR TKI targeting C797S mutations in NSCLC. Although 1st, 2nd, and 3rd Generation EGFR TKIs have been used with some success, recurrence occurs in most patients including those on 3rd Generation TKIs such as Osimertinib. Currently, there are no approved therapies for patients who developed EGFR C797S mutations due to the use of 3rd Generation EGFR TKIs and with the high propensity of these cancers to metastasize to the brain, there is an urgent need to develop an effective drug with high blood-brain barrier permeability as well. 'JIN-A02', a novel oral EGFR TKI, which is effective against C797S double and triple mutations and have a high brain penetrance, is therefore expected to become the most promising Best-in-Class 4th-generation EGFR TKI in NSCLC patients with limited or no viable treatment options.
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SOURCE J INTS BIO | https://www.kbtx.com/prnewswire/2023/07/31/j-ints-bio-novel-oral-4th-generation-egfr-tki-jin-a02-dosing-first-patient-global-multi-center-phase-12-clinical-study-began/ | 2023-07-31T05:21:39 | 0 | https://www.kbtx.com/prnewswire/2023/07/31/j-ints-bio-novel-oral-4th-generation-egfr-tki-jin-a02-dosing-first-patient-global-multi-center-phase-12-clinical-study-began/ |
DHAKA, Bangladesh, July 31, 2023 /PRNewswire/ -- Nagad, a popular mobile money carrier based in Bangladesh, has emerged as a unicorn startup only in four years of its journey – the fastest in Bangladesh to reach this remarkable feat.
In recognition of the achievement, Tanvir A Mishuk, founder and managing director of Nagad Ltd., received the "Fastest to Unicorn Award" from Honourable Prime Minister of People's Republic of Bangladesh Sheikh Hasina at the inaugural ceremony of the two-day "Bangladesh Startup Summit 2023" in Hotel InterContinental Dhaka on 29 July 2023, hosted by Startup Bangladesh Ltd., the flagship venture capital company of the Government of Bangladesh's ICT Division.
Nagad has reshaped the country's MFS industry with one after another disruptive innovation and inspired confidence among people to embrace its products and services that are convenient and affordable. In this way, the state-owned mobile money carrier has established itself as the fastest unicorn startup in Bangladesh.
Presenting a keynote at the startup summit, State Minister for Information and Communication Technology Zunaid Ahmed Palak lauded Nagad's contribution to building a smart economy in Bangladesh.
Founder and Managing Director of Nagad Ltd. Tanvir A Mishuk said, "The way Digital Bangladesh is marching ahead we should have achieved the unicorn status much earlier. Now, our challenge is to take our company's valuation to USD 2 billion."
Increasing the valuation is not Nagad's main target, rather, it has embarked on its journey mainly to bring unbanked people under financial inclusion and get them used to digital payments, he also, adding, "We have already come a long way in meeting our target."
The way payments continue to evolve in keeping with people's changing lifestyle, there is no denying the fact that cashless is the future. Bangladesh government has taken many initiatives to attract people to digital payments. To complement the country's digital vision, Nagad is also working relentlessly to introduce new products and services required to accelerate the country's transition to a cashless society.
To grow into a complete financial solution, the MFS provider is going to establish a digital bank that will make available all financial services on a single platform. The mobile money carrier has already prepared itself accordingly.
"If we get the licence for digital bank, we will introduce collateral-free loans for small informal businesses who now take loans from moneylenders at 40% interest rate per day," said the Nagad MD.
If everything continues to go in the right direction, Bangladesh will emerge as a Smart Nation by 2041, envisioned by PM Sheikh Hasina.
About Nagad Ltd (https://www.nagad.com.bd/)
Nagad Limited is one of the leading MFS operators in Bangladesh's payment industry with 80 million registered customers and an average daily transaction of about USD 112 million. The digital payment platform, known as a successful public-private partnership between Bangladesh Postal Department and the private sector, was inaugurated in 2019 by Prime Minister Sheikh Hasina of the People's Republic of Bangladesh.
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SOURCE Nagad Limited | https://www.kalb.com/prnewswire/2023/07/31/nagad-becomes-bangladeshs-fastest-unicorn/ | 2023-07-31T05:21:44 | 0 | https://www.kalb.com/prnewswire/2023/07/31/nagad-becomes-bangladeshs-fastest-unicorn/ |
DHAKA, Bangladesh, July 31, 2023 /PRNewswire/ -- Nagad, a popular mobile money carrier based in Bangladesh, has emerged as a unicorn startup only in four years of its journey – the fastest in Bangladesh to reach this remarkable feat.
In recognition of the achievement, Tanvir A Mishuk, founder and managing director of Nagad Ltd., received the "Fastest to Unicorn Award" from Honourable Prime Minister of People's Republic of Bangladesh Sheikh Hasina at the inaugural ceremony of the two-day "Bangladesh Startup Summit 2023" in Hotel InterContinental Dhaka on 29 July 2023, hosted by Startup Bangladesh Ltd., the flagship venture capital company of the Government of Bangladesh's ICT Division.
Nagad has reshaped the country's MFS industry with one after another disruptive innovation and inspired confidence among people to embrace its products and services that are convenient and affordable. In this way, the state-owned mobile money carrier has established itself as the fastest unicorn startup in Bangladesh.
Presenting a keynote at the startup summit, State Minister for Information and Communication Technology Zunaid Ahmed Palak lauded Nagad's contribution to building a smart economy in Bangladesh.
Founder and Managing Director of Nagad Ltd. Tanvir A Mishuk said, "The way Digital Bangladesh is marching ahead we should have achieved the unicorn status much earlier. Now, our challenge is to take our company's valuation to USD 2 billion."
Increasing the valuation is not Nagad's main target, rather, it has embarked on its journey mainly to bring unbanked people under financial inclusion and get them used to digital payments, he also, adding, "We have already come a long way in meeting our target."
The way payments continue to evolve in keeping with people's changing lifestyle, there is no denying the fact that cashless is the future. Bangladesh government has taken many initiatives to attract people to digital payments. To complement the country's digital vision, Nagad is also working relentlessly to introduce new products and services required to accelerate the country's transition to a cashless society.
To grow into a complete financial solution, the MFS provider is going to establish a digital bank that will make available all financial services on a single platform. The mobile money carrier has already prepared itself accordingly.
"If we get the licence for digital bank, we will introduce collateral-free loans for small informal businesses who now take loans from moneylenders at 40% interest rate per day," said the Nagad MD.
If everything continues to go in the right direction, Bangladesh will emerge as a Smart Nation by 2041, envisioned by PM Sheikh Hasina.
About Nagad Ltd (https://www.nagad.com.bd/)
Nagad Limited is one of the leading MFS operators in Bangladesh's payment industry with 80 million registered customers and an average daily transaction of about USD 112 million. The digital payment platform, known as a successful public-private partnership between Bangladesh Postal Department and the private sector, was inaugurated in 2019 by Prime Minister Sheikh Hasina of the People's Republic of Bangladesh.
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SOURCE Nagad Limited | https://www.kbtx.com/prnewswire/2023/07/31/nagad-becomes-bangladeshs-fastest-unicorn/ | 2023-07-31T05:21:46 | 1 | https://www.kbtx.com/prnewswire/2023/07/31/nagad-becomes-bangladeshs-fastest-unicorn/ |
NANJING, China, July 31, 2023 /PRNewswire/ -- Nanjing Leads Biolabs Co., Ltd. (hereinafter referred to as "Leads Biolabs" or "Company") announced today that the National Medical Products Administration (NMPA) and the U.S. Food and Drug Administration (FDA) have approved its first-in-human Investigational New Drug (IND) applications for LBL-034, an anti-GPRC5D/CD3 bispecific antibody invented by Leads Biolabs with global intellectual property rights, for the treatment of relapsed/refractory multiple myeloma. Currently, no GPRC5D-targeting antibody has been approved for marketing.
This is a first-in-human, single-arm, multicenter, open-label, dose-escalation and expansion clinical study, and plans to enroll patients with relapsed/refractory multiple myeloma who have failed prior therapies including but not limited to at least one proteasome inhibitor (PI), one immunomodulator (IMiD) as well as other standard treatments. This study aims to evaluate the safety and tolerability of LBL-034, determine the recommended Phase II dose and assess its efficacy in patients with multiple myeloma.
"Despite recent progress and continuous advancements in multiple myeloma, the time between recurrences has been steadily decreasing, particularly as the number of treatment lines increases. This ultimately leads to emergence of relapsed or refractory multiple myeloma, reaffirming its status as an incurable malignant tumor that poses a serious threat to human life. In light of this challenging reality, the urgent need for more effective and innovative treatment options has never been more evident." said Dr. Charles Cai, Chief Medical Officer of Leads Biolabs, "LBL-034 adopts a unique molecular design, which enables the drug to specifically bind to GPRC5D-expressing tumor cells with high affinity, and reduces the risk of non-specific activation of T-cells, thereby enhancing anti-tumor efficacy and reducing potential risk of immunotoxicity. LBL-034 demonstrated robust anti-tumor activities and good safety profile in pre-clinical studies. We adhere to our tradition of innovation and aim to deliver an important, novel and effective treatment option for patients with poor prognosis of relapsed/refractory multiple myeloma."
About GPRC5D:
G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D) is a C-type 7-channel transmembrane receptor protein. GPRC5D is low expressed in normal human tissues but specifically overexpressed in multiple myeloma. The intensity of GPRC5D expression is an independent prognostic factor in multiple myeloma, and its overexpression is significantly associated with reduced overall survival. Therefore, GPRC5D may be an important potential target for the treatment of plasma cell diseases such as multiple myeloma.
About multiple myeloma:
Multiple myeloma is a malignant plasma cell disease caused by abnormal proliferation of clonal plasma cells, accounting for 10-15% of hematologic malignancies and about 1.4% of all malignancies. It is the second most common hematological malignancy in adults after non-Hodgkin's lymphoma and mostly occurs in the elderly. According to the data released by the World Health Organization (WHO), the number of new cases and deaths of multiple myeloma worldwide in 2020 were 176,000 and 117,000 respectively, and the number of new cases and deaths of multiple myeloma in China were 21,000 and 16,000 respectively. Currently, multiple myeloma is still an incurable malignant tumor, and the five-year survival rate of patients is approximately 24.8% in China, 33.3% in Japan, and 46.7% in the United States. In recent years, with the successful development of proteasome inhibitors (PIs), immunomodulatory drugs (IMiDs), selective nuclear output inhibitors, CD38-targeted antibodies, bispecific antibodies, and CAR-T cell therapies, the tumor response rate and survival prognosis have been significantly improved. However, multiple myeloma remains an unmet clinical need for more effective treatments.
About LBL-034:
LBL-034 is a humanized IgG1 subtype asymmetric bispecific antibody targeting both GPRC5D and CD3 and Leads Biolabs fully owns the worldwide intellectual property rights. LBL-034 induces T-cell-mediated killing of myeloma cells by redirecting CD3+ T-cells to myeloma cells expressing GPRC5D.
LBL-034 has the potential to be a transformative best-in-class GPRC5D-targeted immunotherapy for multiple myeloma. Clinical studies are planned to evaluate the safety and efficacy of LBL-034 in patients with relapsed/refractory multiple myeloma.
Nanjing Leads Biolabs Co., Ltd. is a clinical-stage biotechnology company founded in Nanjing by a team of senior U.S.-trained antibody drug developers. Since 2014, Leads Biolabs has been dedicated to the discovery and development of novel antibody drugs with independent intellectual property rights for the treatment of oncology and other major diseases of high unmet medical needs, particularly the challenges in cancer immunotherapy. Our extensive R&D pipeline consist of more than twenty novel tumor immunotherapy molecules based on monoclonal and bispecific antibody technology platforms. Leads Biolabs is committed to providing safe, effective, accessible and affordable new drugs to address the unmet needs of patients around the world.
For more information, please visit: https://www.leadsbiolabs.com
Business contact: bd@leadsbiolabs.com
View original content:
SOURCE LEADS BIOLABS | https://www.kalb.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ | 2023-07-31T05:21:50 | 0 | https://www.kalb.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ |
NANJING, China, July 31, 2023 /PRNewswire/ -- Nanjing Leads Biolabs Co., Ltd. (hereinafter referred to as "Leads Biolabs" or "Company") announced today that the National Medical Products Administration (NMPA) and the U.S. Food and Drug Administration (FDA) have approved its first-in-human Investigational New Drug (IND) applications for LBL-034, an anti-GPRC5D/CD3 bispecific antibody invented by Leads Biolabs with global intellectual property rights, for the treatment of relapsed/refractory multiple myeloma. Currently, no GPRC5D-targeting antibody has been approved for marketing.
This is a first-in-human, single-arm, multicenter, open-label, dose-escalation and expansion clinical study, and plans to enroll patients with relapsed/refractory multiple myeloma who have failed prior therapies including but not limited to at least one proteasome inhibitor (PI), one immunomodulator (IMiD) as well as other standard treatments. This study aims to evaluate the safety and tolerability of LBL-034, determine the recommended Phase II dose and assess its efficacy in patients with multiple myeloma.
"Despite recent progress and continuous advancements in multiple myeloma, the time between recurrences has been steadily decreasing, particularly as the number of treatment lines increases. This ultimately leads to emergence of relapsed or refractory multiple myeloma, reaffirming its status as an incurable malignant tumor that poses a serious threat to human life. In light of this challenging reality, the urgent need for more effective and innovative treatment options has never been more evident." said Dr. Charles Cai, Chief Medical Officer of Leads Biolabs, "LBL-034 adopts a unique molecular design, which enables the drug to specifically bind to GPRC5D-expressing tumor cells with high affinity, and reduces the risk of non-specific activation of T-cells, thereby enhancing anti-tumor efficacy and reducing potential risk of immunotoxicity. LBL-034 demonstrated robust anti-tumor activities and good safety profile in pre-clinical studies. We adhere to our tradition of innovation and aim to deliver an important, novel and effective treatment option for patients with poor prognosis of relapsed/refractory multiple myeloma."
About GPRC5D:
G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D) is a C-type 7-channel transmembrane receptor protein. GPRC5D is low expressed in normal human tissues but specifically overexpressed in multiple myeloma. The intensity of GPRC5D expression is an independent prognostic factor in multiple myeloma, and its overexpression is significantly associated with reduced overall survival. Therefore, GPRC5D may be an important potential target for the treatment of plasma cell diseases such as multiple myeloma.
About multiple myeloma:
Multiple myeloma is a malignant plasma cell disease caused by abnormal proliferation of clonal plasma cells, accounting for 10-15% of hematologic malignancies and about 1.4% of all malignancies. It is the second most common hematological malignancy in adults after non-Hodgkin's lymphoma and mostly occurs in the elderly. According to the data released by the World Health Organization (WHO), the number of new cases and deaths of multiple myeloma worldwide in 2020 were 176,000 and 117,000 respectively, and the number of new cases and deaths of multiple myeloma in China were 21,000 and 16,000 respectively. Currently, multiple myeloma is still an incurable malignant tumor, and the five-year survival rate of patients is approximately 24.8% in China, 33.3% in Japan, and 46.7% in the United States. In recent years, with the successful development of proteasome inhibitors (PIs), immunomodulatory drugs (IMiDs), selective nuclear output inhibitors, CD38-targeted antibodies, bispecific antibodies, and CAR-T cell therapies, the tumor response rate and survival prognosis have been significantly improved. However, multiple myeloma remains an unmet clinical need for more effective treatments.
About LBL-034:
LBL-034 is a humanized IgG1 subtype asymmetric bispecific antibody targeting both GPRC5D and CD3 and Leads Biolabs fully owns the worldwide intellectual property rights. LBL-034 induces T-cell-mediated killing of myeloma cells by redirecting CD3+ T-cells to myeloma cells expressing GPRC5D.
LBL-034 has the potential to be a transformative best-in-class GPRC5D-targeted immunotherapy for multiple myeloma. Clinical studies are planned to evaluate the safety and efficacy of LBL-034 in patients with relapsed/refractory multiple myeloma.
Nanjing Leads Biolabs Co., Ltd. is a clinical-stage biotechnology company founded in Nanjing by a team of senior U.S.-trained antibody drug developers. Since 2014, Leads Biolabs has been dedicated to the discovery and development of novel antibody drugs with independent intellectual property rights for the treatment of oncology and other major diseases of high unmet medical needs, particularly the challenges in cancer immunotherapy. Our extensive R&D pipeline consist of more than twenty novel tumor immunotherapy molecules based on monoclonal and bispecific antibody technology platforms. Leads Biolabs is committed to providing safe, effective, accessible and affordable new drugs to address the unmet needs of patients around the world.
For more information, please visit: https://www.leadsbiolabs.com
Business contact: bd@leadsbiolabs.com
View original content:
SOURCE LEADS BIOLABS | https://www.kbtx.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ | 2023-07-31T05:21:52 | 1 | https://www.kbtx.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ |
More experienced principals leave the profession at higher rates
WASHINGTON, July 31, 2023 /PRNewswire/ -- Roughly 1 in 10 (11 percent) public school principals left the profession between the 2020-21 and 2021-22 school years, according to data from the National Teacher and Principal Survey (NTPS) released today by the National Center for Education Statistics (NCES), the statistical center within the U.S. Department of Education's Institute of Education Sciences (IES).
"Principal attrition is higher in public schools than it was 5 years ago, and veteran public school leaders with more years of experience leave the profession at higher rates than those with less experience," said NCES Commissioner Peggy G. Carr. "Principals are critical supports for a school's teachers and learners, and the country needs leaders in every school who are committed to the success of each student. These data are a valuable snapshot for those at the district and state levels who must address the issue of principal turnover in their schools."
Approximately 80 percent of 2020-21 public school principals remained at the same school one year later ("stayers"), which was lower than the percentage of 2016-17 public school principals who were still at their school 1 year later (82 percent). Six percent of 2020-21 public school principals moved to a different school ("movers"), and 11 percent left the principalship ("leavers"). For private school principals in 2020-21, approximately 83 percent remained at the same school during the following school year, 2 percent moved to a different school, and 10 percent left the principalship.
Additionally, among 2020-21 public school principals who somewhat or strongly agreed they would leave the principalship as soon as possible if they could get a higher paying job (about 25 percent), approximately 73 percent stayed the following school year, while about 15 percent left the profession.
"These data are critical to understanding patterns of principal attrition," said NCES Associate Commissioner Chris Chapman. "We are able to observe how principal attrition has changed over the years, as well as how principal attrition and mobility vary based on characteristics of the principals and their schools."
The report released today includes selected findings from the Principal Follow-up Survey (PFS), a longitudinal component of the National Teacher and Principal Survey (NTPS), which is a nationally representative survey of public and private K-12 schools, principals, and teachers in the 50 states and the District of Columbia. Data were collected from January 2022 through June 2022. The sample included about 6,500 public school principals and about 1,800 private school principals, for a total sample size of about 8,300 principals.
The data were collected as a follow-up to the 2020-21 NTPS to provide attrition and mobility information about principals in K-12 public and private schools. The purpose was to ascertain how many principals from the 2020-21 school year still worked as a principal in the same school 1 year later ("stayer"), how many had moved to become a principal in another school ("mover"), and how many were no longer working as a principal ("leaver").
Key Findings
- Of all public school principals in 2020-21, 11 percent left the profession by the 2021-22 school year. This was higher than in 2016-17, when 10 percent of all public school principals had left the profession since 2015-16, but not measurably different from the 2012-13 school year, when 12 percent of all public school principals had left the profession since the previous school year, or from 2008-09, when 12 percent of all public schools had left the profession since the previous school year.
- Of all public school principals in 2020-21 with more than 10 years of experience as a principal at any school, 15 percent left the profession by the 2021-22 school year. Of those principals with 10 years or more experience as a principal in their current school, 16 percent left the profession.
- A higher percentage of school principals 55 years of age or older left the profession compared to principals between 45-54 years of age.
- Among the 9 percent of 2020-21 public school principals with a salary of less than $75,000, 76 percent remained at the same school during the 2021–22 school year, 7 percent moved to a different school, and 13 percent left the principalship.
- Among the 33 percent of 2020-21 public school principals with a salary of $115,000 or more, 81 percent remained at the same school during the 2021-22 school year, 6 percent moved to a different school, and 10 percent left the principalship.
- Among the 62 percent of 2020-21 private school principals with a salary of less than $75,000, 81 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 10 percent left the principalship.
- Among the 13 percent of 2020-21 private school principals with a salary of $115,000 or more, 85 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 8 percent left the principalship.
The National Center for Education Statistics, a principal agency of the U.S. Federal Statistical System, is the statistical center of the U.S. Department of Education and the primary federal entity for collecting and analyzing data related to education in the U.S. and other nations. NCES fulfills a congressional mandate to collect, collate, analyze, and report complete statistics on the condition and progress of American education; conduct and publish reports; and review and report on education activities internationally.
Follow NCES on Twitter, Facebook, LinkedIn, and YouTube and subscribe to the NCES Newsflash to receive email notifications when new data is released.
The Institute of Education Sciences (IES) is the independent and nonpartisan statistics, research, and evaluation arm of the U.S. Department of Education. Its mission is to provide scientific evidence on which to ground education practice and policy and to share this information in formats that are useful and accessible to educators, parents, policymakers, researchers, and the public.
CONTACT: Josh Delarosa, National Center for Education Statistics, ARIS.NCES@ed.gov
James Elias, Hager Sharp, jelias@hagersharp.com
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SOURCE National Center for Education Statistics | https://www.kalb.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ | 2023-07-31T05:21:57 | 1 | https://www.kalb.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ |
Partnership adds cryptocurrency as a payment option for merchants using Optty's universal payment platform
SINGAPORE, July 30, 2023 /PRNewswire/ -- Optty, the world's first universal payments platform, today announced a new partnership with Triple-A, a licensed crypto payment gateway, to add cryptocurrency as a payment option on the platform. As the central hub connecting and streamlining a robust global network of Buy Now Pay Later (BNPL) providers, this milestone marks the launch of Optty's sixth payment architecture, further expanding viable payment options for merchants and convenience for their end customers.
Sign-up and integration with Optty is free. To get started, please visit: https://www.optty.com/merchant-account
"As the world's first true universal payments platform, Optty is agnostic and supportive of payments inclusion, a unique position that is designed to help retailers offer more choice than ever at checkout," said Natasha Zurnamer, CEO and founder of Optty. "With one simplified integration, not only can retailers access over 90 BNPLs and local payment methods in over 120 countries — they can now switch on crypto payments, a natural progression in our aim to simplify payments for retailers all over the world."
The first crypto payment gateway to be licensed by the Monetary Authority of Singapore, Triple-A is also licensed in Europe, through Banque de France's ACPR, and registered with the United States Financial Crimes Enforcement Network (FinCEN). Through the collaboration with Triple-A's white label crypto payment gateway, Optty enables retailers and merchants to offer a wide range of payment methods. This allows them to test and learn which payment types best resonate with their customers.
Tapping into diverse consumer payment preferences
With Optty's vast global network of gateways that license the company's unique payment stacks, merchants and retailers can now leverage Triple-A's gateway to accept cryptocurrencies such as Bitcoin (BTC), Ethereum (ETH), Tether (USDT), and USD Coin (USDC). Triple-A's crypto payment gateway is compatible with all crypto wallets, allowing customers to make hassle-free payments using their preferred wallet.
Through real-time crypto-to-fiat conversions facilitated by Triple-A, retailers can receive payments in cryptocurrencies without the need to manage them on their balance sheets and constantly monitor fluctuating exchange rates. Retailers enjoy next-day local currency bank settlements in 50+ currencies, enabling quick access to funds in their preferred currency. Additionally, businesses have the option to offer their customers the convenience of paying through Binance Pay.
Optty already offers Buy Now Pay Later, Debit and Credit, Digital Wallets, Peer to Peer payments, and bank transfer options, and the addition of crypto enables merchants to tap into the spending power of 420 million crypto owners worldwide. Optty plans to further expand payment architectures to a total of nine by the end of 2023.
"We are excited to partner with Optty and bring crypto payments to their merchants," said Eric Barbier, CEO of Triple-A. "This collaboration will help merchants take advantage of the growing demand for cryptocurrency payments, without the hassle of managing crypto assets on their balance sheets."
Disruption through simplification
Previously, retailers and merchants would need to spend a great deal of time and money on complex, one-by-one payment integration processes. Optty changed all this by eliminating it, revolutionizing the way merchants access payments methods globally. Available across ecommerce, IVR, and in-store, it is a true PaaS that offers retailers a simplified integration while providing a seamless and direct commercial partnership channel, enabling an application process with every payment provider in the solution.
About Optty
As a PaaS, Optty is the world's first true universal payments platform that integrates over 90 installment (BNPL) brands — more than any other existing single integration solution globally — and offers six payment architectures, soon to be nine by the end of 2023. Its payments-, partner- and channel-agnostic approach delivers wide payments connectivity globally to schemes, acquirers, gateways and retailers alike and offers a full white-label, customisable interface with hierarchy built in for network expansion ease.
For more information, please visit: https://www.optty.com/
About Triple-A
Triple-A is a licensed crypto payment gateway that helps businesses increase their revenue by enabling crypto payments and payouts, giving them access to the spending power of the fast-growing 420m+ cryptocurrency users.
Triple-A's white label crypto payments solutions allow businesses from all industries to leverage the benefits of the growing crypto market without being exposed to volatility risk or having to handle or convert digital currencies. Their solutions are compatible with all wallets, easy to integrate and offer instant confirmation, locked-in exchange rates and chargeback protection.
Licensed by the Monetary Authority of Singapore (MAS) and trusted by over 15,000 businesses, Triple-A makes accepting crypto payments simple for businesses across the globe.
For more information, please visit https://triple-a.io/.
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SOURCE Optty | https://www.kbtx.com/prnewswire/2023/07/31/optty-partners-with-triple-a-expand-payment-architectures-into-cryptocurrencies/ | 2023-07-31T05:21:59 | 0 | https://www.kbtx.com/prnewswire/2023/07/31/optty-partners-with-triple-a-expand-payment-architectures-into-cryptocurrencies/ |
THUNDER BAY, Ontario, Canada — The Duluth Huskies will go into August and the Northwoods League Great Plains Division All-Star Game on a three-game losing streak after falling 4-3 to the Thunder Bay Border Cats on Sunday afternoon.
Thunder Bay scored three runs on three hits in the first inning off Duluth pitcher Devin Dodson, creating a deficit the Huskies could not quite overcome.
Down 4-1 after four innings, Lucas Kelly's RBI single made it 4-2 in the fifth and a third Duluth run scored on a passed ball in the seventh. However, Duluth stranded the bases loaded in that inning, then grounded into a double play with the bases loaded and one out in the bottom of the ninth to end the game.
Jared Mettam was 2-for-5 to lead Duluth's offense, whose output of three runs equaled their lowest of the season's second half (a 4-3 loss at St. Cloud on July 6).
Dodson took the loss, allowing four runs on six hits in four innings. He struck out four and walked three.
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The NWL Great Plains Division teams are off until Thursday for All-Star festivities in Bismarck, North Dakota, including a Home Run Challenge on Monday night and the All-Star Game on Tuesday.
Duluth goes into the last 10 games of the regular season 16-10 but faces a tough mountain to climb, as Great Plains East opponent La Crosse has gone an eye-popping 20-4 in the second half. The Huskies resume at home vs. Eau Claire on Thursday night. | https://www.duluthnewstribune.com/sports/huskies-lose-third-straight-to-border-cats | 2023-07-31T05:22:03 | 1 | https://www.duluthnewstribune.com/sports/huskies-lose-third-straight-to-border-cats |
HANOI, Vietnam, July 31, 2023 /PRNewswire/ -- SeABank's stock (SSB) has been officially selected by the Ho Chi Minh City Stock Exchange (HOSE) to be included in the VN30-Index basket - an index representing the top 30 stocks with the highest market capitalization and liquidity listed on the HOSE.
At the end of the trading session on July 28, 2023, the closing price of SSB's stock was 29,700 VND per share, bringing SeABank's market capitalization to over 72,875 billion VND, equivalent to nearly 3.07 billion USD.
According to the press release, on July 17, 2023, HOSE announced the portfolio of stocks included in the VN30 and VN-Finlead indexes, which would be effective from August 7, 2023. SSB was chosen to be included in the VN30 basket as it met the requirements set by the HOSE Index Rules. With an average market capitalization of nearly 65,000 billion Vietnamese dongs over the past six months, SSB is one of the largest capitalized stocks among those not included in the previous VN30 basket.
Throughout its operations, SeABank prioritizes transparency by providing information to shareholders, partners, and customers, complying with legal regulations, and following the directives of the Government and the State Bank of Vietnam to stabilize the market, ensure smooth operations, and promote business activities, thereby contributing to the country's socio-economic development.
SeABank's stock (SSB) was officially listed on the HOSE on March 24, 2021, with a reference price of 16,800 Vietnamese dongs per share on its first trading day. It has consistently experienced stable growth since then. In June 2023, SeABank successfully issued shares for dividend payment and additional capital from shareholder funds (bonus shares) with a total ratio of 20.3% to increase its charter capital to 24,537 billion Vietnamese dong.
Previously, SSB was also added to the Morgan Stanley Capital Index (MSCI) Frontier Markets Index starting from March 1, 2023. According to experts, stocks included in the MSCI Frontier Markets Index may be targeted by ETF (Exchange Traded Fund) funds that track frontier market stocks. Some funds use this index as a reference for investment or replicate its portfolio.
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SOURCE SeABank | https://www.kalb.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ | 2023-07-31T05:22:04 | 1 | https://www.kalb.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ |
DULUTH — It's just one of several mountains Joel Johnson of Hugo, Minnesota has tackled in his golf career, but on Sunday at Ridgeview Country Club, Johnson got over the hump, and quickly, to win the Arrowhead Invitational for the first time.
Johnson, the 2022 runner-up, who last month competed in the U.S. Senior Open for the second consecutive year, won the first four holes of the match play final vs. Ryan Bakken before cruising to a 6-and-5 victory in the 97th annual event.
"I've played enough of these where I try not to think too much about what the score is and play golf. Just give it the best on every shot. I know it's a simple formula but if you start thinking too much about, 'Oh I'm way behind or I'm way ahead,' you're not going to be successful," he said.
Earlier in the day, Johnson (the No. 5 seed in the 32-man bracket) prevailed 1-up in a 2022 championship rematch with Matt Mellin, a battle of "par trains," in which the two combined for 17 pars and one bogey on the back nine, Mellin's bogey on 15, which ended up deciding the match.
"This is such a great event, and it's awesome. I'm extremely excited to win this," Johnson said.
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Johnson has yet to make the cut in the Senior Open (the 2023 edition of which took place at SentryWorld in Stevens Point, Wisconsin last month), but competing with some of golf's grandest names has a way of sharpening any player's toolbag.
"You play in front of hundreds and thousands of people on the hardest golf course you've ever seen in your life. It's extremely scary. I don't know how else to put it," he said.
"You never feel completely comfortable on a course like this (Ridgeview), but it (playing at big events like the U.S. Senior Open) does help you."
His early lead might have come as a surprise, looking at earlier rounds of the tournament. Bakken, a Ridgeview player, had been sporting a hot hand. He was one of only three players to break par in the qualifying round, recording three birdies and an eagle in his last five holes to shoot 3-under 67. He had ended three of his four rounds in the match play bracket before the 16th hole.
After defeating Brandon Owen 4-and-3 in a morning semifinal that may not have been that close, putting problems brought his momentum to a screeching halt early in the championship.
"I had been hitting the ball good all week. My game is in a way where it relies on my putting pretty heavily, and I blasted a putt on No. 2 like 30 feet by, and usually if I do that early, it gets in my head. I just really struggled with the putter ever since. Joel drained some long ones and it really took the wind out of my sails," Bakken said.
Bakken recovered to win the fifth hole, but 3-down was as close as he'd get the rest of the way and Johnson closed out the match with a par 5 on 13.
"I got up and down from a lot of places I probably shouldn't have so, overall, so I probably would guess overall my short game was what got me to this," Johnson said.
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Big shot decides senior title
In an all-Northland Country Club duel for the senior division championship, Shane Johnson delivered a shot to remember.
All square with Mike Weinkauf after Johnson lost the 16th and 17th holes, Johnson hit an approach shot from the right rough that trickled to inside 10 feet from the hole.
"It felt great. When it came off the club, I was very fortunate to go that way," he said.
The job wasn't done, though. Weinkauf, whose second shot was just short of the green, took a long birdie putt that came up short, making Johnson earn his championship the hard way, but he did for a 1-up victory.
"That putt was really a big breaker. I was very fortunate to read it a little bit," Johnson said. | https://www.duluthnewstribune.com/sports/johnson-wins-first-arrowhead-title-in-a-rout | 2023-07-31T05:22:04 | 1 | https://www.duluthnewstribune.com/sports/johnson-wins-first-arrowhead-title-in-a-rout |
SUPERIOR — The Lake Superior Sea Dogs held off a comeback effort from the Ashland Merchants to win 6-4 at Morrie Arnovich Field on Sunday in the regular-season and Upper 13 League finale for both squads.
Lake Superior jumped out to a 5-0 lead by the middle innings. Owen Hindermann took advantage of three Ashland errors in the second inning to reach base, advance and later score. Eric Hinnenkamp drove in a second run for Lake Superior in the fourth inning and the home team scored three times in the fifth inning on two hits, two walks, a stolen base, two wild pitches and an error.
Sam Larson's RBI single for Lake Superior re-established some cushion after Ashland drew to within 5-3, before the Merchants made a two-out rally that put the tying run on base and the go-ahead run at the plate before Hindermann shut the game down with a strikeout in relief.
Hinnenkamp earned the win, allowing three runs on nine his with 13 strikeouts in his 8 2/3 innings. Alex Busick and Brock McDermid had two hits apiece.
Lake Superior caps the regular season 6-5 (6-4 in the Upper 13 League). | https://www.duluthnewstribune.com/sports/sea-dogs-hold-off-late-charge-to-win-regular-season-finale | 2023-07-31T05:22:05 | 0 | https://www.duluthnewstribune.com/sports/sea-dogs-hold-off-late-charge-to-win-regular-season-finale |
The smoky haze looks likely for parts of the Northland throughout most of the day ahead. Besides the smoke, the sky will be fairly sunny and with the combination of light winds will make for a mild afternoon. The breeze picks up some out of the southeast Tuesday. I'm seeing high temperatures peak in the upper 70s to lower 80s Tuesday with warmer highs on the way for Wednesday and Thursday. Our next chance of showers and thunderstorms will pass by Tuesday night into early Wednesday. Highs may stay in the 80s through Friday with the forecast this weekend looking to peak in 70s.
Warmer temperatures back midweek
Highs will warm into the 70s again today, but expect more 80s for the Northland midweek.
ADVERTISEMENT | https://www.duluthnewstribune.com/weather/warmer-temperatures-back-midweek | 2023-07-31T05:22:05 | 0 | https://www.duluthnewstribune.com/weather/warmer-temperatures-back-midweek |
More experienced principals leave the profession at higher rates
WASHINGTON, July 31, 2023 /PRNewswire/ -- Roughly 1 in 10 (11 percent) public school principals left the profession between the 2020-21 and 2021-22 school years, according to data from the National Teacher and Principal Survey (NTPS) released today by the National Center for Education Statistics (NCES), the statistical center within the U.S. Department of Education's Institute of Education Sciences (IES).
"Principal attrition is higher in public schools than it was 5 years ago, and veteran public school leaders with more years of experience leave the profession at higher rates than those with less experience," said NCES Commissioner Peggy G. Carr. "Principals are critical supports for a school's teachers and learners, and the country needs leaders in every school who are committed to the success of each student. These data are a valuable snapshot for those at the district and state levels who must address the issue of principal turnover in their schools."
Approximately 80 percent of 2020-21 public school principals remained at the same school one year later ("stayers"), which was lower than the percentage of 2016-17 public school principals who were still at their school 1 year later (82 percent). Six percent of 2020-21 public school principals moved to a different school ("movers"), and 11 percent left the principalship ("leavers"). For private school principals in 2020-21, approximately 83 percent remained at the same school during the following school year, 2 percent moved to a different school, and 10 percent left the principalship.
Additionally, among 2020-21 public school principals who somewhat or strongly agreed they would leave the principalship as soon as possible if they could get a higher paying job (about 25 percent), approximately 73 percent stayed the following school year, while about 15 percent left the profession.
"These data are critical to understanding patterns of principal attrition," said NCES Associate Commissioner Chris Chapman. "We are able to observe how principal attrition has changed over the years, as well as how principal attrition and mobility vary based on characteristics of the principals and their schools."
The report released today includes selected findings from the Principal Follow-up Survey (PFS), a longitudinal component of the National Teacher and Principal Survey (NTPS), which is a nationally representative survey of public and private K-12 schools, principals, and teachers in the 50 states and the District of Columbia. Data were collected from January 2022 through June 2022. The sample included about 6,500 public school principals and about 1,800 private school principals, for a total sample size of about 8,300 principals.
The data were collected as a follow-up to the 2020-21 NTPS to provide attrition and mobility information about principals in K-12 public and private schools. The purpose was to ascertain how many principals from the 2020-21 school year still worked as a principal in the same school 1 year later ("stayer"), how many had moved to become a principal in another school ("mover"), and how many were no longer working as a principal ("leaver").
Key Findings
- Of all public school principals in 2020-21, 11 percent left the profession by the 2021-22 school year. This was higher than in 2016-17, when 10 percent of all public school principals had left the profession since 2015-16, but not measurably different from the 2012-13 school year, when 12 percent of all public school principals had left the profession since the previous school year, or from 2008-09, when 12 percent of all public schools had left the profession since the previous school year.
- Of all public school principals in 2020-21 with more than 10 years of experience as a principal at any school, 15 percent left the profession by the 2021-22 school year. Of those principals with 10 years or more experience as a principal in their current school, 16 percent left the profession.
- A higher percentage of school principals 55 years of age or older left the profession compared to principals between 45-54 years of age.
- Among the 9 percent of 2020-21 public school principals with a salary of less than $75,000, 76 percent remained at the same school during the 2021–22 school year, 7 percent moved to a different school, and 13 percent left the principalship.
- Among the 33 percent of 2020-21 public school principals with a salary of $115,000 or more, 81 percent remained at the same school during the 2021-22 school year, 6 percent moved to a different school, and 10 percent left the principalship.
- Among the 62 percent of 2020-21 private school principals with a salary of less than $75,000, 81 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 10 percent left the principalship.
- Among the 13 percent of 2020-21 private school principals with a salary of $115,000 or more, 85 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 8 percent left the principalship.
The National Center for Education Statistics, a principal agency of the U.S. Federal Statistical System, is the statistical center of the U.S. Department of Education and the primary federal entity for collecting and analyzing data related to education in the U.S. and other nations. NCES fulfills a congressional mandate to collect, collate, analyze, and report complete statistics on the condition and progress of American education; conduct and publish reports; and review and report on education activities internationally.
Follow NCES on Twitter, Facebook, LinkedIn, and YouTube and subscribe to the NCES Newsflash to receive email notifications when new data is released.
The Institute of Education Sciences (IES) is the independent and nonpartisan statistics, research, and evaluation arm of the U.S. Department of Education. Its mission is to provide scientific evidence on which to ground education practice and policy and to share this information in formats that are useful and accessible to educators, parents, policymakers, researchers, and the public.
CONTACT: Josh Delarosa, National Center for Education Statistics, ARIS.NCES@ed.gov
James Elias, Hager Sharp, jelias@hagersharp.com
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SOURCE National Center for Education Statistics | https://www.kbtx.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ | 2023-07-31T05:22:05 | 0 | https://www.kbtx.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ |
HANOI, Vietnam, July 31, 2023 /PRNewswire/ -- SeABank's stock (SSB) has been officially selected by the Ho Chi Minh City Stock Exchange (HOSE) to be included in the VN30-Index basket - an index representing the top 30 stocks with the highest market capitalization and liquidity listed on the HOSE.
At the end of the trading session on July 28, 2023, the closing price of SSB's stock was 29,700 VND per share, bringing SeABank's market capitalization to over 72,875 billion VND, equivalent to nearly 3.07 billion USD.
According to the press release, on July 17, 2023, HOSE announced the portfolio of stocks included in the VN30 and VN-Finlead indexes, which would be effective from August 7, 2023. SSB was chosen to be included in the VN30 basket as it met the requirements set by the HOSE Index Rules. With an average market capitalization of nearly 65,000 billion Vietnamese dongs over the past six months, SSB is one of the largest capitalized stocks among those not included in the previous VN30 basket.
Throughout its operations, SeABank prioritizes transparency by providing information to shareholders, partners, and customers, complying with legal regulations, and following the directives of the Government and the State Bank of Vietnam to stabilize the market, ensure smooth operations, and promote business activities, thereby contributing to the country's socio-economic development.
SeABank's stock (SSB) was officially listed on the HOSE on March 24, 2021, with a reference price of 16,800 Vietnamese dongs per share on its first trading day. It has consistently experienced stable growth since then. In June 2023, SeABank successfully issued shares for dividend payment and additional capital from shareholder funds (bonus shares) with a total ratio of 20.3% to increase its charter capital to 24,537 billion Vietnamese dong.
Previously, SSB was also added to the Morgan Stanley Capital Index (MSCI) Frontier Markets Index starting from March 1, 2023. According to experts, stocks included in the MSCI Frontier Markets Index may be targeted by ETF (Exchange Traded Fund) funds that track frontier market stocks. Some funds use this index as a reference for investment or replicate its portfolio.
View original content to download multimedia:
SOURCE SeABank | https://www.kbtx.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ | 2023-07-31T05:22:12 | 0 | https://www.kbtx.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ |
For more than 20 years, the National Eating Disorders Association (NEDA) has operated a phone line and online platform for people seeking help with anorexia, bulimia, and other eating disorders. Last year, nearly 70,000 individuals used the helpline.
NEDA shuttered that service in May. Instead, the non-profit will use a chatbot called Tessa that was designed by eating disorder experts, with funding from NEDA.
(When NPR first aired a radio story about this on May 24, Tessa was up and running online. But since then, both the chatbot's page and a NEDA article about Tessa have been taken down. When asked why, a NEDA official said the bot is being "updated," and the latest "version of the current program [will be] available soon.")
Paid staffers and volunteers for the NEDA hotline expressed shock and sadness at the decision, saying it could further isolate the thousands of people who use the helpline when they feel they have nowhere else to turn.
"These young kids...don't feel comfortable coming to their friends or their family or anybody about this," says Katy Meta, a 20-year-old college student who has volunteered for the helpline. "A lot of these individuals come on multiple times because they have no other outlet to talk with anybody...That's all they have, is the chat line."
The decision is part of a larger trend: many mental health organizations and companies are struggling to provide services and care in response to a sharp escalation in demand, and some are turning to chatbots and AI, despite the fact that clinicians are still trying to figure out how to effectively deploy them, and for what conditions.
The research team that developed Tessa has published studies showing it can help users improve their body image. But they've also released studies showing the chatbot may miss red flags (like users saying they plan to starve themselves) and could even inadvertently reinforce harmful behavior.
More demands on the helpline increased stresses at NEDA
On March 31, NEDA notified the helpline's five staffers that they would be laid off in June, just days after the workers formally notified their employer that they had formed a union. "We will, subject to the terms of our legal responsibilities, [be] beginning to wind down the helpline as currently operating," NEDA board chair Geoff Craddock told helpline staff on a call March 31. NPR obtained audio of the call. "With a transition to Tessa, the AI-assisted technology, expected around June 1."
NEDA's leadership denies the helpline decision had anything to do with the unionization, but told NPR it became necessary after the COVID-19 pandemic, when eating disorders surged and the number of calls, texts and messages to the helpline more than doubled. Many of those reaching out were suicidal, dealing with abuse, or experiencing some kind of medical emergency. NEDA's leadership contends the helpline wasn't designed to handle those types of situations.
The increase in crisis-level calls also raises NEDA's legal liability, managers explained in an email sent March 31 to current and former volunteers, informing them the helpline was ending and that NEDA would "begin to pivot to the expanded use of AI-assisted technology."
"What has really changed in the landscape are the federal and state requirements for mandated reporting for mental and physical health issues (self-harm, suicidality, child abuse)," according to the email, which NPR obtained. "NEDA is now considered a mandated reporter and that hits our risk profile---changing our training and daily work processes and driving up our insurance premiums. We are not a crisis line; we are a referral center and information provider."
COVID created a "perfect storm" for eating disorders
When it was time for a volunteer shift on the helpline, Meta usually logged in from her dorm room at Dickinson College in Pennsylvania. During a video interview with NPR, the room appeared cozy and warm, with twinkly lights strung across the walls, and a striped crochet quilt on the bed.
Meta recalls a recent conversation on the helpline's messaging platform with a girl who said she was 11. The girl said she had just confessed to her parents that she was struggling with an eating disorder, but the conversation had gone badly.
"The parents said that they 'didn't believe in eating disorders,' and [told their daughter] 'You just need to eat more. You need to stop doing this,'" Meta recalls. "This individual was also suicidal and exhibited traits of self-harm as well...it was just really heartbreaking to see."
Eating disorders are a common, serious, and sometimes fatal illness. An estimated nine percent of Americans experience an eating disorder during their lifetime. Eating disorders also have some of the highest mortality rates among mental illnesses, with an estimated death toll of more than 10,000 Americans each year.
But after the COVID-19 pandemic hit, closing schools and forcing people into prolonged isolation, crisis calls and messages like the one Meta describes became far more frequent on the helpline. That's because the pandemic created a "perfect storm" for eating disorders, according to Dr. Dasha Nicholls, a psychiatrist and eating disorder researcher at Imperial College London.
In the U.S., the rate of pediatric hospitalizations and ER visits surged. For many people, the stress, isolation and anxiety of the pandemic was compounded by major changes to their eating and exercise habits, not to mention their daily routines.
On the NEDA helpline, the volume of contacts increased by more than 100% compared to pre-pandemic levels. And workers taking those calls and messages were witnessing the escalating stress and symptoms in real time.
"Eating disorders thrive in isolation, so COVID and shelter-in-place was a tough time for a lot of folks struggling," explains Abbie Harper, a helpline staff associate. "And what we saw on the rise was kind of more crisis-type calls, with suicide, self-harm, and then child abuse or child neglect, just due to kids having to be at home all the time, sometimes with not-so-supportive folks."
There was another 11-year-old girl, this one in Greece, who said she was terrified to talk to her parents "because she thought she might get in trouble" for having an eating disorder, recalls volunteer Nicole Rivers. On the helpline, the girl found reassurance that her illness "was not her fault."
"We were actually able to educate her about what eating disorders are," Rivers says. "And that there are ways that she could teach her parents about this as well, so that they may be able to help support her and get her support from other professionals."
What personal contact can provide
Because many volunteers have successfully battled eating disorders themselves, they're uniquely attuned to experiences of those reaching out, Harper says. "Part of what can be very powerful in eating disorder recovery, is connecting to folks who have a lived experience. When you know what it's been like for you, and you know that feeling, you can connect with others over that."
Until a few weeks ago, the helpline was run by just 5-6 paid staffers, two supervisors, and depended on a rotating roster of 90-165 volunteers at any given time, according to NEDA.
Yet even after lockdowns ended, NEDA's helpline volume remained elevated above pre-pandemic levels, and the cases continued to be clinically severe. Staff felt overwhelmed, undersupported, and increasingly burned out, and turnover increased, according to multiple interviews with helpline staffers.
The helpline staff formally notified NEDA that their unionization vote had been certified on March 27. Four days later, they learned their positions were being eliminated.
It was no longer possible for NEDA to continue operating the helpline, says Lauren Smolar, NEDA's Vice President of Mission and Education.
"Our volunteers are volunteers," Smolar says. "They're not professionals. They don't have crisis training. And we really can't accept that kind of responsibility." Instead, she says, people seeking crisis help should be reaching out to resources like 988, a 24/7 suicide and crisis hotline that connects people with trained counselors.
The surge in volume also meant the helpline was unable to respond immediately to 46% of initial contacts, and it could take between 6 and 11 days to respond to messages.
"And that's frankly unacceptable in 2023, for people to have to wait a week or more to receive the information that they need, the specialized treatment options that they need," she says.
After learning in the March 31 email that the helpline would be phased out, volunteer Faith Fischetti, 22, tried the chatbot out on her own. "I asked it a few questions that I've experienced, and that I know people ask when they want to know things and need some help," says Fischetti, who will begin pursuing a master's in social work in the fall. But her interactions with Tessa were not reassuring: "[The bot] gave links and resources that were completely unrelated" to her questions.
Fischetti's biggest worry is that someone coming to the NEDA site for help will leave because they "feel that they're not understood, and feel that no one is there for them. And that's the most terrifying thing to me."
She wonders why NEDA can't have both: a 24/7 chatbot to pre-screen users and reroute them to a crisis hotline if needed, and a human-run helpline to offer connection and resources. "My question became, why are we getting rid of something that is so helpful?"
A chatbot designed to help treat eating disorders
Tessa the chatbot was created to help a specific cohort: people with eating disorders who never receive treatment.
Only 20% of people with eating disorders get formal help, according to Ellen Fitzsimmons-Craft, a psychologist and professor at Washington University School of Medicine in St. Louis. Her team created Tessa after receiving funding from NEDA in 2018, with the goal of looking for ways technology could help fill the treatment gap.
"Unfortunately, most mental health providers receive no training in eating disorders," Fitzsimmons-Craft says. Her team's ultimate goal is to provide free, accessible, evidence-based treatment tools that leverage the power and reach of technology.
But no one intends Tessa to be a universal fix, she says. "I don't think it's an open-ended tool for you to talk to, and feel like you're just going to have access to kind of a listening ear, maybe like the helpline was. It's really a tool in its current form that's going to help you learn and use some strategies to address your disordered eating and your body image."
Tessa is a "rule-based" chatbot, meaning she's programmed with a limited set of possible responses. She is not chatGPT, and cannot generate unique answers in response to specific queries. "So she can't go off the rails, so to speak," Fitzsimmons-Craft says.
In its current form, Tessa can guide users through an interactive, weeks-long course about body positivity, based on cognitive behavioral therapy tools. Additional content about binging, weight concerns, and regular eating are also being developed but are not yet available for users.
There's evidence the concept can help. Fitzsimmons-Craft's team did a small study that found college students who interacted with Tessa had significantly greater reductions in "weight/shape concerns" compared to a control group at both 3- and 6-month follow-ups.
But even the best-intentioned technology may carry risks. Fitzsimmons-Craft's team published a different study looking at ways the chatbot "unexpectedly reinforced harmful behaviors at times." For example, the chatbot would give users a prompt: "Please take a moment to write about when you felt best about your body?"
Some of the responses included: "When I was underweight and could see my bones." "I feel best about my body when I ignore it and don't think about it at all."
The chatbot's response seemed to ignore the troubling aspects of such responses — and even to affirm negative thinking — when it would reply: "It is awesome that you can recognize a moment when you felt confident in your skin, let's keep working on making you feel this good more often."
Researchers were able to troubleshoot some of those issues. But the chatbot still missed red flags, the study found, like when it asked: "What is a small healthy eating habit goal you would like to set up before you start your next conversation?'"
One user replied, "'Don't eat.'"
"'Take a moment to pat yourself on the back for doing this hard work, <<USER>>!'" the chatbot responded.
The study described the chatbot's capabilities as something that could be improved over time, with more inputs and tweaks: "With many more responses, it would be possible to train the AI to identify and respond better to problematic responses."
MIT professor Marzyeh Ghassemi has seen issues like this crop up in her own research developing machine learning to improve health.
Large language models and chatbots are inevitably going to make mistakes, but "sometimes they tend to be wrong more often for certain groups, like women and minorities," she says.
If people receive bad advice or instructions from a bot, "people sometimes have a difficulty not listening to it," Ghassemi adds. "I think it sets you up for this really negative outcome...especially for a mental health crisis situation, where people may be at a point where they're not thinking with absolute clarity. It's very important that the information that you give them is correct and is helpful to them."
And if the value of the live helpline was the ability to connect with a real person who deeply understands eating disorders, Ghassemi says a chatbot can't do that.
"If people are experiencing a majority of the positive impact of these interactions because the person on the other side understands fundamentally the experience they're going through, and what a struggle it's been, I struggle to understand how a chatbot could be part of that."
Copyright 2023 Michigan Radio | https://www.kcbx.org/npr-top-news/2023-05-31/national-eating-disorders-association-phases-out-human-helpline-pivots-to-chatbot | 2023-07-31T05:22:34 | 0 | https://www.kcbx.org/npr-top-news/2023-05-31/national-eating-disorders-association-phases-out-human-helpline-pivots-to-chatbot |
Updated July 24, 2023 at 10:51 AM ET
Elon Musk has finally done it: turned Twitter to X.
While the unveiling of X on a Sunday caught many people unaware, it was not a surprise.
The platform's owner has talked about turning it into "X" for months, while being a bit vague about what that exactly means. Does X represent a major business experiment? A radical new concept for on-line living? Or is it simply one man's obsession with the 24th letter of the alphabet?
Probably it's all of the above.
"X," Musk tweeted in April.
A few days earlier a filing in a federal court case in California confirmed that Twitter had been folded into X Corp.
In announcing the company's new CEO, Linda Yaccarino, this May, Musk wrote on then-Twitter: "Looking forward to working with Linda to transform this platform into X, the everything app."
Yaccarino seems keen to do exactly that, posting on Sunday that "X will be the platform that can deliver, well....everything."
In some ways, the letter "X" frames everything about Musk's ambitions, according to biographers, from where he is headed to where he got his entrepreneurial start.
X.com, the bank where it began
According to Ashlee Vance, the author of Elon Musk: Tesla, SpaceX, and the Quest for a Fantastic Future, Musk's obsession with the letter X began with one of the billionaire's earliest ventures, X.com, which later merged with a competitor to become PayPal.
"Everyone tried to talk him out of naming the company that back then because of the sexual innuendos, but he really liked it and stuck with it," said Vance.
In 2017, Musk repurchased the url "X.com" from PayPal, tweeting that the domain "has great sentimental value."
X, the Tesla model
"X marks the spot in a lot of ways for Elon Musk," said Tim Higgins, a Wall Street Journal reporter and the author of Power Play: Tesla, Elon Musk, and the Bet of the Century. "It's kind of this common theme throughout."
The letter X became the name of Tesla's third model, which debuted in 2015.
"The idea being that the Tesla models would spell out the word 'sexy,'" Higgins said. But Ford owns the right to the Model E, which is why Musk later settled on the Model 3, "kind of a backwards E," he said.
X, the first letter of his youngest son's name
In 2020, Musk and his then-partner, Grimes, welcomed a son via surrogate, naming him X Æ A-12 Musk. (Æ is pronounced "ash," Musk told controversial podcast host Joe Rogan.)
The couple named their second child, a girl, Exa Dark Sideræl Musk. (It's now been changed to "Y.")
X, the everything app
But lately, "X" has referred to Musk's newest ambition, building an "everything app" akin to China's popular WeChat, which doesn't yet have a U.S.-parallel.
"He wants to create an app similar to how WeChat is used in China, where it's part of the fabric of day-to-day life. You use it to communicate, to consume news, to buy things, to pay your rent, to book appointments with your doctor and even to pay fines," said Vance.
Vance says following the WeChat model makes sense with what Musk wants for Twitter. "The company clearly needs a new, bigger business if it's to make the type of money that would justify his investment and satisfy his ambition," he said.
Weeks before he shelled out $44 billion to acquire Twitter in October, Musk tweeted, "Buying Twitter is an accelerant to creating X, the everything app."
X...?
But Musk's obsession with the letter X is still something of a mystery even to his biographers, like Higgins.
"Whether it's kind of mysterious, like something pulled from a comic book, or 'X marks the spot,' it's hard to know with him," Higgins said. "It also just kind of sounds cool."
This story was updated on July 24, 2023, by Lisa Lambert. contributed to this story
Copyright 2023 NPR. To see more, visit https://www.npr.org. | https://www.kcbx.org/npr-top-news/npr-top-news/2023-05-12/a-brief-biography-of-x-the-letter-that-elon-musk-has-plastered-everywhere | 2023-07-31T05:22:40 | 0 | https://www.kcbx.org/npr-top-news/npr-top-news/2023-05-12/a-brief-biography-of-x-the-letter-that-elon-musk-has-plastered-everywhere |
MEDFORD, Ore. – A delegation from Crater Lake National Park’s sister park in Slovenia, just wrapped up a trip to Crater Lake to strengthen the relationship between the two parks.
The visitors from the one and only national park in Slovenia, Triglav National Park, ended their visit Sunday.
They went to Crater Lake National Park to collaborate with park officials, and to share each other’s knowledge and practices, so they can learn from each other.
“Somethings can be transferred from one park to another. You get to see how dedicated they are to their work, and it also gives you the motivation to work harder and to go for your goals even more dedicated,” said Tit Potocnik, Director of Triglav National Park.
Potocnik said he and his team learned a lot on the trip. the main thing they learned from Crater Lake, is how they manage visitors and how visitor fees are used to help park operations.
© 2023 KOBI-TV NBC5. All rights reserved unless otherwise stated. | https://kobi5.com/news/international-park-managers-pay-a-visit-to-crater-lake-to-share-practices-212524/ | 2023-07-31T05:23:55 | 0 | https://kobi5.com/news/international-park-managers-pay-a-visit-to-crater-lake-to-share-practices-212524/ |
MEDFORD, Ore. – Some of the strongest men and women in the valley competed against each other in the WABDL Northwest Powerlifting Championship.
CrossFit Steelhead hosted the championship for the past 25 years as a qualifier for the World Association of Benchers and Deadlifters, World Championship in Las Vegas.
The over 40 competitors competed for a chance to compete in the world championship in Las Vegas, as well as to set both state and national records in the sport.
Organizers said they host the event every year out of love for the sport.
“It’s very gratifying, we put this meet on every year to help keep the sport going. It’s gratifying to see that we’re adding some new blood to the sport,” said Dan Guches, with the WABDL Northwest Championship.
Guches said there were some new and old competitors at this year’s competition, with some competitors in their 60s and 70s going on to set some records at the competition.
© 2023 KOBI-TV NBC5. All rights reserved unless otherwise stated. | https://kobi5.com/news/local-news/athletes-test-their-strength-at-the-northwest-powerlifting-championship-212520/ | 2023-07-31T05:24:01 | 1 | https://kobi5.com/news/local-news/athletes-test-their-strength-at-the-northwest-powerlifting-championship-212520/ |
BONANZA, Ore. – Firefighters are planning to wrap up operations on the Golden Fire Tuesday morning.
The Golden Fire started a week ago Saturday and burned 2,137 acres. The fire is 48% contained.
Firefighters were able to put out some small flare-ups Saturday during the red flag warning in the area.
ODF said they’re confident they can give control of the fire, to the local fire district early this week.
“With those two to three hundred feet of mop up around the perimeter that’s a huge accomplishment, and we’re at 48 percent containment and that containment is going to potentially jump up some more, leaving the local district with confidence from the team that they can handle it,” said Jennifer Case, Information Officer for the Golden Fire.
Firefighters say there’s still a lot of work to be done. They’re starting to remove fire hoses around parts of the fire and starting to repair dozer lines to prepare for winter rain.
© 2023 KOBI-TV NBC5. All rights reserved unless otherwise stated. | https://kobi5.com/news/local-news/firefighters-looking-to-demobilize-from-the-golden-fire-tuesday-morning-212526/ | 2023-07-31T05:24:08 | 0 | https://kobi5.com/news/local-news/firefighters-looking-to-demobilize-from-the-golden-fire-tuesday-morning-212526/ |
Six migrant workers were struck Sunday afternoon by an SUV in a Walmart parking lot in North Carolina from what police are calling "an intentional assault with a vehicle."
"All six were transported to Atrium Health – Lincoln with various injuries. None of the injuries appear to be life threatening," the Lincolnton Police Department said in a Facebook post.
Police say they're still looking for the vehicle and driver involved in the incident, which they said took place at 1:17 pm ET. In the Facebook post, they describe the vehicle as an older model SUV with a luggage rack, and the driver as an older white male.
The motive for the attack is also still under investigation. Police told NPR via telephone late Sunday there is no further information.
Lincolnton is a small city of some 11,800 people located about an hour outside of Charlotte.
Copyright 2023 NPR. To see more, visit https://www.npr.org. | https://www.kunm.org/npr-news/npr-news/2023-07-30/an-suv-strikes-6-migrant-workers-in-walmart-parking-lot-in-north-carolina | 2023-07-31T05:24:33 | 1 | https://www.kunm.org/npr-news/npr-news/2023-07-30/an-suv-strikes-6-migrant-workers-in-walmart-parking-lot-in-north-carolina |
Erratic winds challenge firefighters battling two major California blazes
MOJAVE NATIONAL PRESERVE, Calif. (AP) — A massive wildfire burning out of control in California’s Mojave National Preserve was spreading rapidly amid erratic winds, while firefighters reported progress against another major blaze to the southwest that prompted evacuations.
The York Fire that erupted Friday near the remote Caruthers Canyon area of the vast wildland preserve crossed the state line into Nevada on Sunday and sent smoke further east into the Las Vegas Valley.
Wind-driven flames 20 feet (6 meters) high in some spots charred more than 110 square miles (284 square kilometers) of desert scrub, juniper and Joshua tree woodland, according to an incident update. There was zero containment.
“The dry fuel acts as a ready ignition source, and when paired with those weather conditions it resulted in long-distance fire run and high flames, leading to extreme fire behavior,” the update said. No structures were threatened.
To the southwest, the Bonny Fire was holding steady at about 3.4 square miles (8.8 square kilometers) in rugged hills of Riverside County. More than 1,300 people were ordered to evacuate their homes Saturday near the community of Aguanga that is home to horse ranches and wineries.
Gusty winds and the chance of thunderstorms into Monday will heighten the risk of renewed growth, the California Department of Forestry and Fire Protection said in a statement.
One firefighter was injured in the blaze, which was 5% contained.
Copyright 2023 The Associated Press. All rights reserved. | https://www.wbtv.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ | 2023-07-31T05:24:37 | 0 | https://www.wbtv.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ |
Erratic winds challenge firefighters battling two major California blazes
MOJAVE NATIONAL PRESERVE, Calif. (AP) — A massive wildfire burning out of control in California’s Mojave National Preserve was spreading rapidly amid erratic winds, while firefighters reported progress against another major blaze to the southwest that prompted evacuations.
The York Fire that erupted Friday near the remote Caruthers Canyon area of the vast wildland preserve crossed the state line into Nevada on Sunday and sent smoke further east into the Las Vegas Valley.
Wind-driven flames 20 feet (6 meters) high in some spots charred more than 110 square miles (284 square kilometers) of desert scrub, juniper and Joshua tree woodland, according to an incident update. There was zero containment.
“The dry fuel acts as a ready ignition source, and when paired with those weather conditions it resulted in long-distance fire run and high flames, leading to extreme fire behavior,” the update said. No structures were threatened.
To the southwest, the Bonny Fire was holding steady at about 3.4 square miles (8.8 square kilometers) in rugged hills of Riverside County. More than 1,300 people were ordered to evacuate their homes Saturday near the community of Aguanga that is home to horse ranches and wineries.
Gusty winds and the chance of thunderstorms into Monday will heighten the risk of renewed growth, the California Department of Forestry and Fire Protection said in a statement.
One firefighter was injured in the blaze, which was 5% contained.
Copyright 2023 The Associated Press. All rights reserved. | https://www.wnem.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ | 2023-07-31T05:25:54 | 0 | https://www.wnem.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ |
Flint City Bucks Playoff run ends in National Semi-Finals
The Bucks lost to Ballard FC 1-0 to miss out on a trip to the National Championship
FLINT, Mich. (WNEM) - The Flint City Bucks were already back in playoff soccer action after winning the Central Conference title on Friday. Tonight the Bucks hosted Ballard FC in the National Semi-Finals.
The Bucks were eliminated from this same spot last year. This time they looked to make the National Championship.
In the first half, Ballard FC had a dangerous opportunity early in the game. Taketo Onodera fired from outside of the box and he scores just under 10 minutes in and Flint City trails 1-0.
The Bucks had multiple opportunities to equalize, including a free kick header that hit the crossbar in the 90th minute. Unfortunately the stellar run ends tonight with Ballard FC defeating the Bucks 1-0 to move on to the National Championship game.
Copyright 2023 WNEM. All rights reserved. | https://www.wnem.com/2023/07/31/flint-city-bucks-playoff-run-ends-national-semi-finals/ | 2023-07-31T05:26:00 | 1 | https://www.wnem.com/2023/07/31/flint-city-bucks-playoff-run-ends-national-semi-finals/ |
SAN FRANCISCO (KRON) — Kung Food, a small business near Alamo Square, was broken into recently. This incident marks the seventh time the San Francisco business has been vandalized or broken into since 2020.
Despite reaching out to local leaders and police, owner Andy Yang has not received any help. The business has signs posted outside letting potential criminals know there is no money inside.
“Posting a sign in front of our door is really our last resort. As a way to express our frustration and our discontentment with our city officials,” said Yang.
The store’s video surveillance shows a man breaking the door open and heading straight to the cash register. He managed to get $100 from the register, along with two iPads.
“The repair cost us about $500,” said Yang. “There’s a bus stop right next to us. If people spot that it’s open, they’re just going to come in and trash the place.”
According to Yang, the break-ins have been an ongoing issue. Back in 2019, he appeared on KRON4 after Kung Food’s first break-in. “Tried to contact District 5 Dean Preston, the supervisor of our district, but just no avail,” said Yang.
Dean Preston’s office told KRON4 they sympathize with what has happened but have no record of Yang reaching out to them.
He said after one of the break-ins, police made an arrest, but the case ended up being dismissed after Yang appeared in court. “What can I do right? That’s how the justice system is set up. It’s not for small businesses, especially here in the city,” said Yang.
Kung Food’s lease ends in February 2024. Yang says he does not want to move his business but if the break-ins continue to happen, he might be forced to. | https://www.kron4.com/news/bay-area/san-francisco-small-business-burglarized-7-times-since-pandemic/ | 2023-07-31T05:26:03 | 0 | https://www.kron4.com/news/bay-area/san-francisco-small-business-burglarized-7-times-since-pandemic/ |
Erratic winds challenge firefighters battling two major California blazes
MOJAVE NATIONAL PRESERVE, Calif. (AP) — A massive wildfire burning out of control in California’s Mojave National Preserve was spreading rapidly amid erratic winds, while firefighters reported progress against another major blaze to the southwest that prompted evacuations.
The York Fire that erupted Friday near the remote Caruthers Canyon area of the vast wildland preserve crossed the state line into Nevada on Sunday and sent smoke further east into the Las Vegas Valley.
Wind-driven flames 20 feet (6 meters) high in some spots charred more than 110 square miles (284 square kilometers) of desert scrub, juniper and Joshua tree woodland, according to an incident update. There was zero containment.
“The dry fuel acts as a ready ignition source, and when paired with those weather conditions it resulted in long-distance fire run and high flames, leading to extreme fire behavior,” the update said. No structures were threatened.
To the southwest, the Bonny Fire was holding steady at about 3.4 square miles (8.8 square kilometers) in rugged hills of Riverside County. More than 1,300 people were ordered to evacuate their homes Saturday near the community of Aguanga that is home to horse ranches and wineries.
Gusty winds and the chance of thunderstorms into Monday will heighten the risk of renewed growth, the California Department of Forestry and Fire Protection said in a statement.
One firefighter was injured in the blaze, which was 5% contained.
Copyright 2023 The Associated Press. All rights reserved. | https://www.wbrc.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ | 2023-07-31T05:26:24 | 0 | https://www.wbrc.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ |
Six migrant workers were struck Sunday afternoon by an SUV in a Walmart parking lot in North Carolina from what police are calling "an intentional assault with a vehicle."
"All six were transported to Atrium Health – Lincoln with various injuries. None of the injuries appear to be life threatening," the Lincolnton Police Department said in a Facebook post.
Police say they're still looking for the vehicle and driver involved in the incident, which they said took place at 1:17 pm ET. In the Facebook post, they describe the vehicle as an older model SUV with a luggage rack, and the driver as an older white male.
The motive for the attack is also still under investigation. Police told NPR via telephone late Sunday there is no further information.
Lincolnton is a small city of some 11,800 people located about an hour outside of Charlotte.
Copyright 2023 NPR. To see more, visit https://www.npr.org. | https://www.mainepublic.org/npr-news/2023-07-30/an-suv-strikes-6-migrant-workers-in-walmart-parking-lot-in-north-carolina | 2023-07-31T05:26:48 | 0 | https://www.mainepublic.org/npr-news/2023-07-30/an-suv-strikes-6-migrant-workers-in-walmart-parking-lot-in-north-carolina |
HONG KONG, July 31, 2023 /PRNewswire/ -- Akeso Inc. ("Akeso", the "Company"; 9926.HK), a commercial-stage biopharmaceutical company focused on developing and commercializing first-in-class and best-in-class innovative medicines globally, today announced that it is expected that the Company will record a profit of not less than RMB2.3 billion for the six months ended June 30, 2023. This is the first time for the Company to achieve half-year profits.
The turnaround from loss to profit during the Reporting Period was mainly attributable to:
- In respect of Ivonescimab (AK112, PD-1/VEGF) independently developed by the Company, the Company has entered into the collaborative and licensing agreement with Summit Therapeutics (details of which are set out in the announcement of the Company dated December 6, 2022). The Company has received the total upfront payment equivalent to US$500 million in full during the first quarter of 2023 (details of which are set out in the announcements of the Company dated January 26, 2023 and March 6, 2023). Part of such upfront payment was recognized as licensing fee income which significantly contributed to the revenue of the Company for the Reporting Period, and amounted to approximately RMB2.9 billion. The revenue recognition of the remaining portion of the upfront payment will be recognized as revenue in batches going forward.
- In respect of the Company's innovative product 开坦尼® (cadonilimab, PD-1/CTLA-4), since its launch in June 2022, it has recorded significant increase of the patients as well as product sales, which reflects the excellent clinical value of cadonilimab. In addition, 安尼可®(penpulimab, PD-1) also continued to contribute to the growth in the Company's product sales revenue during the Reporting Period.
- The Company has continued to optimise its cost management capabilities in a scientific and efficient way and has achieved better results in cost control while accelerating innovative products development and pipelines advancement.
About Akeso
Akeso (HKEX: 09926) is a commercial-stage biopharmaceutical company committed to the discovery, development, manufacturing, and commercialization of innovative medicines with high unmet medical needs worldwide. Founded in 2012, the Company has established a comprehensive in-house drug development platform (ACE Platform) and know-how, including R&D, clinical development, CMC (Chemistry, Manufacturing, and Controls), and commercialization capabilities.
With fully integrated multi-functional platform, Akeso is internally working on a robust pipeline of over 30 innovative assets in the fields of cancer, autoimmune disease, inflammation, metabolic disease, and other major therapeutic areas. 19 assets have entered clinical stage. Leveraging in-house developed bispecific platform technology ("Tetrabody technology"), the Company has advanced four potential first-in-class bispecific antibody drugs into market or clinical development, including cadonilimab (PD-1/CTLA-4), ivonescimab (PD-1/VEGF), PD-1/LAG-3, TIGIT/TGF-Beta bispecific antibodies. In June 2022, cadonilimab was approved by the NMPA and became the first commercialized PD-1 based bispecific drug globally. Another Akeso internally discovered and developed oncology product, penpulimab (a PD-1 antibody), was granted marketing approval in China in August 2021. In December 2022, the Company out-licensed breakthrough bispecific antibody, ivonescimab (PD-1/VEGF bi-specific antibody, AK112), with up to US$5 Billion total potential deal value to Summit Therapeutics for development and commercialization in the U.S., Canada, Europe, and Japan.
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SOURCE Akeso, Inc. | https://www.wbtv.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ | 2023-07-31T05:28:16 | 0 | https://www.wbtv.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ |
SEOUL, South Korea, July 31, 2023 /PRNewswire/ -- J INTS BIO announced the successful dosing of the first patient in its global multi-center Phase 1/2 clinical study of 'JIN-A02' on 31st July at Severance Hospital, Seoul, Korea.
More clinical sites will follow suit, including seven more hospitals in Korea (National Cancer Center, Chungbuk National University Hospital, Samsung Seoul Hospital, Seoul National University Hospital, Seoul St. Mary's Hospital, St. Vincent Hospital, Asan Medical Center), two in the United States, and one in Thailand.
This global phase 1/2 clinical trial seeks to evaluate the safety, pharmacokinetics and anti-tumor activity of "JIN-A02" in advanced NSCLC patients carrying EGFR mutations.
'JIN-A02' is a novel orally administered 4th Generation EGFR TKI, which is highly selective for and strongly inhibits NSCLC with C797S double or triple mutations, showing efficacy even against intracranial tumors by exhibiting high blood-brain barrier penetrance.
Anna Jo, CEO of J INTS BIO, said, "We expect the positive results of 'JIN-A02' in the pre-clinical studies to translate to positive outcomes for patients in the clinical trial" adding that, "We hope also to proceed with the application for designation of orphan drug, and thereby quickly occupy the global NSCLC therapy market through conditional use."
About J INTS BIO
J INTS BIO is a bio company specialized in developing innovative anti-cancer and orphan drugs to realize the goal of changing lives and improving health for patients around the world. J INTS BIO's teams have prior multi-year experience in multinational pharmaceutical companies and CROs and track records in medical, regulatory affairs, drug discovery and development.
About 'JIN-A02'
'JIN-A02' is a novel orally administered 4th Generation EGFR TKI targeting C797S mutations in NSCLC. Although 1st, 2nd, and 3rd Generation EGFR TKIs have been used with some success, recurrence occurs in most patients including those on 3rd Generation TKIs such as Osimertinib. Currently, there are no approved therapies for patients who developed EGFR C797S mutations due to the use of 3rd Generation EGFR TKIs and with the high propensity of these cancers to metastasize to the brain, there is an urgent need to develop an effective drug with high blood-brain barrier permeability as well. 'JIN-A02', a novel oral EGFR TKI, which is effective against C797S double and triple mutations and have a high brain penetrance, is therefore expected to become the most promising Best-in-Class 4th-generation EGFR TKI in NSCLC patients with limited or no viable treatment options.
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SOURCE J INTS BIO | https://www.wbtv.com/prnewswire/2023/07/31/j-ints-bio-novel-oral-4th-generation-egfr-tki-jin-a02-dosing-first-patient-global-multi-center-phase-12-clinical-study-began/ | 2023-07-31T05:28:23 | 0 | https://www.wbtv.com/prnewswire/2023/07/31/j-ints-bio-novel-oral-4th-generation-egfr-tki-jin-a02-dosing-first-patient-global-multi-center-phase-12-clinical-study-began/ |
DHAKA, Bangladesh, July 31, 2023 /PRNewswire/ -- Nagad, a popular mobile money carrier based in Bangladesh, has emerged as a unicorn startup only in four years of its journey – the fastest in Bangladesh to reach this remarkable feat.
In recognition of the achievement, Tanvir A Mishuk, founder and managing director of Nagad Ltd., received the "Fastest to Unicorn Award" from Honourable Prime Minister of People's Republic of Bangladesh Sheikh Hasina at the inaugural ceremony of the two-day "Bangladesh Startup Summit 2023" in Hotel InterContinental Dhaka on 29 July 2023, hosted by Startup Bangladesh Ltd., the flagship venture capital company of the Government of Bangladesh's ICT Division.
Nagad has reshaped the country's MFS industry with one after another disruptive innovation and inspired confidence among people to embrace its products and services that are convenient and affordable. In this way, the state-owned mobile money carrier has established itself as the fastest unicorn startup in Bangladesh.
Presenting a keynote at the startup summit, State Minister for Information and Communication Technology Zunaid Ahmed Palak lauded Nagad's contribution to building a smart economy in Bangladesh.
Founder and Managing Director of Nagad Ltd. Tanvir A Mishuk said, "The way Digital Bangladesh is marching ahead we should have achieved the unicorn status much earlier. Now, our challenge is to take our company's valuation to USD 2 billion."
Increasing the valuation is not Nagad's main target, rather, it has embarked on its journey mainly to bring unbanked people under financial inclusion and get them used to digital payments, he also, adding, "We have already come a long way in meeting our target."
The way payments continue to evolve in keeping with people's changing lifestyle, there is no denying the fact that cashless is the future. Bangladesh government has taken many initiatives to attract people to digital payments. To complement the country's digital vision, Nagad is also working relentlessly to introduce new products and services required to accelerate the country's transition to a cashless society.
To grow into a complete financial solution, the MFS provider is going to establish a digital bank that will make available all financial services on a single platform. The mobile money carrier has already prepared itself accordingly.
"If we get the licence for digital bank, we will introduce collateral-free loans for small informal businesses who now take loans from moneylenders at 40% interest rate per day," said the Nagad MD.
If everything continues to go in the right direction, Bangladesh will emerge as a Smart Nation by 2041, envisioned by PM Sheikh Hasina.
About Nagad Ltd (https://www.nagad.com.bd/)
Nagad Limited is one of the leading MFS operators in Bangladesh's payment industry with 80 million registered customers and an average daily transaction of about USD 112 million. The digital payment platform, known as a successful public-private partnership between Bangladesh Postal Department and the private sector, was inaugurated in 2019 by Prime Minister Sheikh Hasina of the People's Republic of Bangladesh.
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SOURCE Nagad Limited | https://www.wbtv.com/prnewswire/2023/07/31/nagad-becomes-bangladeshs-fastest-unicorn/ | 2023-07-31T05:28:29 | 1 | https://www.wbtv.com/prnewswire/2023/07/31/nagad-becomes-bangladeshs-fastest-unicorn/ |
NANJING, China, July 31, 2023 /PRNewswire/ -- Nanjing Leads Biolabs Co., Ltd. (hereinafter referred to as "Leads Biolabs" or "Company") announced today that the National Medical Products Administration (NMPA) and the U.S. Food and Drug Administration (FDA) have approved its first-in-human Investigational New Drug (IND) applications for LBL-034, an anti-GPRC5D/CD3 bispecific antibody invented by Leads Biolabs with global intellectual property rights, for the treatment of relapsed/refractory multiple myeloma. Currently, no GPRC5D-targeting antibody has been approved for marketing.
This is a first-in-human, single-arm, multicenter, open-label, dose-escalation and expansion clinical study, and plans to enroll patients with relapsed/refractory multiple myeloma who have failed prior therapies including but not limited to at least one proteasome inhibitor (PI), one immunomodulator (IMiD) as well as other standard treatments. This study aims to evaluate the safety and tolerability of LBL-034, determine the recommended Phase II dose and assess its efficacy in patients with multiple myeloma.
"Despite recent progress and continuous advancements in multiple myeloma, the time between recurrences has been steadily decreasing, particularly as the number of treatment lines increases. This ultimately leads to emergence of relapsed or refractory multiple myeloma, reaffirming its status as an incurable malignant tumor that poses a serious threat to human life. In light of this challenging reality, the urgent need for more effective and innovative treatment options has never been more evident." said Dr. Charles Cai, Chief Medical Officer of Leads Biolabs, "LBL-034 adopts a unique molecular design, which enables the drug to specifically bind to GPRC5D-expressing tumor cells with high affinity, and reduces the risk of non-specific activation of T-cells, thereby enhancing anti-tumor efficacy and reducing potential risk of immunotoxicity. LBL-034 demonstrated robust anti-tumor activities and good safety profile in pre-clinical studies. We adhere to our tradition of innovation and aim to deliver an important, novel and effective treatment option for patients with poor prognosis of relapsed/refractory multiple myeloma."
About GPRC5D:
G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D) is a C-type 7-channel transmembrane receptor protein. GPRC5D is low expressed in normal human tissues but specifically overexpressed in multiple myeloma. The intensity of GPRC5D expression is an independent prognostic factor in multiple myeloma, and its overexpression is significantly associated with reduced overall survival. Therefore, GPRC5D may be an important potential target for the treatment of plasma cell diseases such as multiple myeloma.
About multiple myeloma:
Multiple myeloma is a malignant plasma cell disease caused by abnormal proliferation of clonal plasma cells, accounting for 10-15% of hematologic malignancies and about 1.4% of all malignancies. It is the second most common hematological malignancy in adults after non-Hodgkin's lymphoma and mostly occurs in the elderly. According to the data released by the World Health Organization (WHO), the number of new cases and deaths of multiple myeloma worldwide in 2020 were 176,000 and 117,000 respectively, and the number of new cases and deaths of multiple myeloma in China were 21,000 and 16,000 respectively. Currently, multiple myeloma is still an incurable malignant tumor, and the five-year survival rate of patients is approximately 24.8% in China, 33.3% in Japan, and 46.7% in the United States. In recent years, with the successful development of proteasome inhibitors (PIs), immunomodulatory drugs (IMiDs), selective nuclear output inhibitors, CD38-targeted antibodies, bispecific antibodies, and CAR-T cell therapies, the tumor response rate and survival prognosis have been significantly improved. However, multiple myeloma remains an unmet clinical need for more effective treatments.
About LBL-034:
LBL-034 is a humanized IgG1 subtype asymmetric bispecific antibody targeting both GPRC5D and CD3 and Leads Biolabs fully owns the worldwide intellectual property rights. LBL-034 induces T-cell-mediated killing of myeloma cells by redirecting CD3+ T-cells to myeloma cells expressing GPRC5D.
LBL-034 has the potential to be a transformative best-in-class GPRC5D-targeted immunotherapy for multiple myeloma. Clinical studies are planned to evaluate the safety and efficacy of LBL-034 in patients with relapsed/refractory multiple myeloma.
Nanjing Leads Biolabs Co., Ltd. is a clinical-stage biotechnology company founded in Nanjing by a team of senior U.S.-trained antibody drug developers. Since 2014, Leads Biolabs has been dedicated to the discovery and development of novel antibody drugs with independent intellectual property rights for the treatment of oncology and other major diseases of high unmet medical needs, particularly the challenges in cancer immunotherapy. Our extensive R&D pipeline consist of more than twenty novel tumor immunotherapy molecules based on monoclonal and bispecific antibody technology platforms. Leads Biolabs is committed to providing safe, effective, accessible and affordable new drugs to address the unmet needs of patients around the world.
For more information, please visit: https://www.leadsbiolabs.com
Business contact: bd@leadsbiolabs.com
View original content:
SOURCE LEADS BIOLABS | https://www.wbtv.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ | 2023-07-31T05:28:36 | 0 | https://www.wbtv.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ |
More experienced principals leave the profession at higher rates
WASHINGTON, July 31, 2023 /PRNewswire/ -- Roughly 1 in 10 (11 percent) public school principals left the profession between the 2020-21 and 2021-22 school years, according to data from the National Teacher and Principal Survey (NTPS) released today by the National Center for Education Statistics (NCES), the statistical center within the U.S. Department of Education's Institute of Education Sciences (IES).
"Principal attrition is higher in public schools than it was 5 years ago, and veteran public school leaders with more years of experience leave the profession at higher rates than those with less experience," said NCES Commissioner Peggy G. Carr. "Principals are critical supports for a school's teachers and learners, and the country needs leaders in every school who are committed to the success of each student. These data are a valuable snapshot for those at the district and state levels who must address the issue of principal turnover in their schools."
Approximately 80 percent of 2020-21 public school principals remained at the same school one year later ("stayers"), which was lower than the percentage of 2016-17 public school principals who were still at their school 1 year later (82 percent). Six percent of 2020-21 public school principals moved to a different school ("movers"), and 11 percent left the principalship ("leavers"). For private school principals in 2020-21, approximately 83 percent remained at the same school during the following school year, 2 percent moved to a different school, and 10 percent left the principalship.
Additionally, among 2020-21 public school principals who somewhat or strongly agreed they would leave the principalship as soon as possible if they could get a higher paying job (about 25 percent), approximately 73 percent stayed the following school year, while about 15 percent left the profession.
"These data are critical to understanding patterns of principal attrition," said NCES Associate Commissioner Chris Chapman. "We are able to observe how principal attrition has changed over the years, as well as how principal attrition and mobility vary based on characteristics of the principals and their schools."
The report released today includes selected findings from the Principal Follow-up Survey (PFS), a longitudinal component of the National Teacher and Principal Survey (NTPS), which is a nationally representative survey of public and private K-12 schools, principals, and teachers in the 50 states and the District of Columbia. Data were collected from January 2022 through June 2022. The sample included about 6,500 public school principals and about 1,800 private school principals, for a total sample size of about 8,300 principals.
The data were collected as a follow-up to the 2020-21 NTPS to provide attrition and mobility information about principals in K-12 public and private schools. The purpose was to ascertain how many principals from the 2020-21 school year still worked as a principal in the same school 1 year later ("stayer"), how many had moved to become a principal in another school ("mover"), and how many were no longer working as a principal ("leaver").
Key Findings
- Of all public school principals in 2020-21, 11 percent left the profession by the 2021-22 school year. This was higher than in 2016-17, when 10 percent of all public school principals had left the profession since 2015-16, but not measurably different from the 2012-13 school year, when 12 percent of all public school principals had left the profession since the previous school year, or from 2008-09, when 12 percent of all public schools had left the profession since the previous school year.
- Of all public school principals in 2020-21 with more than 10 years of experience as a principal at any school, 15 percent left the profession by the 2021-22 school year. Of those principals with 10 years or more experience as a principal in their current school, 16 percent left the profession.
- A higher percentage of school principals 55 years of age or older left the profession compared to principals between 45-54 years of age.
- Among the 9 percent of 2020-21 public school principals with a salary of less than $75,000, 76 percent remained at the same school during the 2021–22 school year, 7 percent moved to a different school, and 13 percent left the principalship.
- Among the 33 percent of 2020-21 public school principals with a salary of $115,000 or more, 81 percent remained at the same school during the 2021-22 school year, 6 percent moved to a different school, and 10 percent left the principalship.
- Among the 62 percent of 2020-21 private school principals with a salary of less than $75,000, 81 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 10 percent left the principalship.
- Among the 13 percent of 2020-21 private school principals with a salary of $115,000 or more, 85 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 8 percent left the principalship.
The National Center for Education Statistics, a principal agency of the U.S. Federal Statistical System, is the statistical center of the U.S. Department of Education and the primary federal entity for collecting and analyzing data related to education in the U.S. and other nations. NCES fulfills a congressional mandate to collect, collate, analyze, and report complete statistics on the condition and progress of American education; conduct and publish reports; and review and report on education activities internationally.
Follow NCES on Twitter, Facebook, LinkedIn, and YouTube and subscribe to the NCES Newsflash to receive email notifications when new data is released.
The Institute of Education Sciences (IES) is the independent and nonpartisan statistics, research, and evaluation arm of the U.S. Department of Education. Its mission is to provide scientific evidence on which to ground education practice and policy and to share this information in formats that are useful and accessible to educators, parents, policymakers, researchers, and the public.
CONTACT: Josh Delarosa, National Center for Education Statistics, ARIS.NCES@ed.gov
James Elias, Hager Sharp, jelias@hagersharp.com
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SOURCE National Center for Education Statistics | https://www.wbtv.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ | 2023-07-31T05:28:43 | 1 | https://www.wbtv.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ |
HANOI, Vietnam, July 31, 2023 /PRNewswire/ -- SeABank's stock (SSB) has been officially selected by the Ho Chi Minh City Stock Exchange (HOSE) to be included in the VN30-Index basket - an index representing the top 30 stocks with the highest market capitalization and liquidity listed on the HOSE.
At the end of the trading session on July 28, 2023, the closing price of SSB's stock was 29,700 VND per share, bringing SeABank's market capitalization to over 72,875 billion VND, equivalent to nearly 3.07 billion USD.
According to the press release, on July 17, 2023, HOSE announced the portfolio of stocks included in the VN30 and VN-Finlead indexes, which would be effective from August 7, 2023. SSB was chosen to be included in the VN30 basket as it met the requirements set by the HOSE Index Rules. With an average market capitalization of nearly 65,000 billion Vietnamese dongs over the past six months, SSB is one of the largest capitalized stocks among those not included in the previous VN30 basket.
Throughout its operations, SeABank prioritizes transparency by providing information to shareholders, partners, and customers, complying with legal regulations, and following the directives of the Government and the State Bank of Vietnam to stabilize the market, ensure smooth operations, and promote business activities, thereby contributing to the country's socio-economic development.
SeABank's stock (SSB) was officially listed on the HOSE on March 24, 2021, with a reference price of 16,800 Vietnamese dongs per share on its first trading day. It has consistently experienced stable growth since then. In June 2023, SeABank successfully issued shares for dividend payment and additional capital from shareholder funds (bonus shares) with a total ratio of 20.3% to increase its charter capital to 24,537 billion Vietnamese dong.
Previously, SSB was also added to the Morgan Stanley Capital Index (MSCI) Frontier Markets Index starting from March 1, 2023. According to experts, stocks included in the MSCI Frontier Markets Index may be targeted by ETF (Exchange Traded Fund) funds that track frontier market stocks. Some funds use this index as a reference for investment or replicate its portfolio.
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SOURCE SeABank | https://www.wbtv.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ | 2023-07-31T05:28:49 | 1 | https://www.wbtv.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ |
NEW YORK (PIX11) — The New York City area received a much-needed break from the heat and humidity Sunday.
There could be some rain Monday morning. Conditions are expected to remain pleasant for the next few days. The temps will remain in the 80s, and humidity will be on the lower side through the middle of the week.
Temperatures will remain in the 80s through the week. With Thursday and Friday bringing a chance of rain to end the week. | https://pix11.com/weather/ny-nj-forecast-temps-in-the-80s-all-week/ | 2023-07-31T05:28:54 | 0 | https://pix11.com/weather/ny-nj-forecast-temps-in-the-80s-all-week/ |
HONG KONG, July 31, 2023 /PRNewswire/ -- Akeso Inc. ("Akeso", the "Company"; 9926.HK), a commercial-stage biopharmaceutical company focused on developing and commercializing first-in-class and best-in-class innovative medicines globally, today announced that it is expected that the Company will record a profit of not less than RMB2.3 billion for the six months ended June 30, 2023. This is the first time for the Company to achieve half-year profits.
The turnaround from loss to profit during the Reporting Period was mainly attributable to:
- In respect of Ivonescimab (AK112, PD-1/VEGF) independently developed by the Company, the Company has entered into the collaborative and licensing agreement with Summit Therapeutics (details of which are set out in the announcement of the Company dated December 6, 2022). The Company has received the total upfront payment equivalent to US$500 million in full during the first quarter of 2023 (details of which are set out in the announcements of the Company dated January 26, 2023 and March 6, 2023). Part of such upfront payment was recognized as licensing fee income which significantly contributed to the revenue of the Company for the Reporting Period, and amounted to approximately RMB2.9 billion. The revenue recognition of the remaining portion of the upfront payment will be recognized as revenue in batches going forward.
- In respect of the Company's innovative product 开坦尼® (cadonilimab, PD-1/CTLA-4), since its launch in June 2022, it has recorded significant increase of the patients as well as product sales, which reflects the excellent clinical value of cadonilimab. In addition, 安尼可®(penpulimab, PD-1) also continued to contribute to the growth in the Company's product sales revenue during the Reporting Period.
- The Company has continued to optimise its cost management capabilities in a scientific and efficient way and has achieved better results in cost control while accelerating innovative products development and pipelines advancement.
About Akeso
Akeso (HKEX: 09926) is a commercial-stage biopharmaceutical company committed to the discovery, development, manufacturing, and commercialization of innovative medicines with high unmet medical needs worldwide. Founded in 2012, the Company has established a comprehensive in-house drug development platform (ACE Platform) and know-how, including R&D, clinical development, CMC (Chemistry, Manufacturing, and Controls), and commercialization capabilities.
With fully integrated multi-functional platform, Akeso is internally working on a robust pipeline of over 30 innovative assets in the fields of cancer, autoimmune disease, inflammation, metabolic disease, and other major therapeutic areas. 19 assets have entered clinical stage. Leveraging in-house developed bispecific platform technology ("Tetrabody technology"), the Company has advanced four potential first-in-class bispecific antibody drugs into market or clinical development, including cadonilimab (PD-1/CTLA-4), ivonescimab (PD-1/VEGF), PD-1/LAG-3, TIGIT/TGF-Beta bispecific antibodies. In June 2022, cadonilimab was approved by the NMPA and became the first commercialized PD-1 based bispecific drug globally. Another Akeso internally discovered and developed oncology product, penpulimab (a PD-1 antibody), was granted marketing approval in China in August 2021. In December 2022, the Company out-licensed breakthrough bispecific antibody, ivonescimab (PD-1/VEGF bi-specific antibody, AK112), with up to US$5 Billion total potential deal value to Summit Therapeutics for development and commercialization in the U.S., Canada, Europe, and Japan.
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SOURCE Akeso, Inc. | https://www.kxii.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ | 2023-07-31T05:28:54 | 1 | https://www.kxii.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ |
SEOUL, South Korea, July 31, 2023 /PRNewswire/ -- J INTS BIO announced the successful dosing of the first patient in its global multi-center Phase 1/2 clinical study of 'JIN-A02' on 31st July at Severance Hospital, Seoul, Korea.
More clinical sites will follow suit, including seven more hospitals in Korea (National Cancer Center, Chungbuk National University Hospital, Samsung Seoul Hospital, Seoul National University Hospital, Seoul St. Mary's Hospital, St. Vincent Hospital, Asan Medical Center), two in the United States, and one in Thailand.
This global phase 1/2 clinical trial seeks to evaluate the safety, pharmacokinetics and anti-tumor activity of "JIN-A02" in advanced NSCLC patients carrying EGFR mutations.
'JIN-A02' is a novel orally administered 4th Generation EGFR TKI, which is highly selective for and strongly inhibits NSCLC with C797S double or triple mutations, showing efficacy even against intracranial tumors by exhibiting high blood-brain barrier penetrance.
Anna Jo, CEO of J INTS BIO, said, "We expect the positive results of 'JIN-A02' in the pre-clinical studies to translate to positive outcomes for patients in the clinical trial" adding that, "We hope also to proceed with the application for designation of orphan drug, and thereby quickly occupy the global NSCLC therapy market through conditional use."
About J INTS BIO
J INTS BIO is a bio company specialized in developing innovative anti-cancer and orphan drugs to realize the goal of changing lives and improving health for patients around the world. J INTS BIO's teams have prior multi-year experience in multinational pharmaceutical companies and CROs and track records in medical, regulatory affairs, drug discovery and development.
About 'JIN-A02'
'JIN-A02' is a novel orally administered 4th Generation EGFR TKI targeting C797S mutations in NSCLC. Although 1st, 2nd, and 3rd Generation EGFR TKIs have been used with some success, recurrence occurs in most patients including those on 3rd Generation TKIs such as Osimertinib. Currently, there are no approved therapies for patients who developed EGFR C797S mutations due to the use of 3rd Generation EGFR TKIs and with the high propensity of these cancers to metastasize to the brain, there is an urgent need to develop an effective drug with high blood-brain barrier permeability as well. 'JIN-A02', a novel oral EGFR TKI, which is effective against C797S double and triple mutations and have a high brain penetrance, is therefore expected to become the most promising Best-in-Class 4th-generation EGFR TKI in NSCLC patients with limited or no viable treatment options.
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SOURCE J INTS BIO | https://www.kxii.com/prnewswire/2023/07/31/j-ints-bio-novel-oral-4th-generation-egfr-tki-jin-a02-dosing-first-patient-global-multi-center-phase-12-clinical-study-began/ | 2023-07-31T05:29:01 | 0 | https://www.kxii.com/prnewswire/2023/07/31/j-ints-bio-novel-oral-4th-generation-egfr-tki-jin-a02-dosing-first-patient-global-multi-center-phase-12-clinical-study-began/ |
DHAKA, Bangladesh, July 31, 2023 /PRNewswire/ -- Nagad, a popular mobile money carrier based in Bangladesh, has emerged as a unicorn startup only in four years of its journey – the fastest in Bangladesh to reach this remarkable feat.
In recognition of the achievement, Tanvir A Mishuk, founder and managing director of Nagad Ltd., received the "Fastest to Unicorn Award" from Honourable Prime Minister of People's Republic of Bangladesh Sheikh Hasina at the inaugural ceremony of the two-day "Bangladesh Startup Summit 2023" in Hotel InterContinental Dhaka on 29 July 2023, hosted by Startup Bangladesh Ltd., the flagship venture capital company of the Government of Bangladesh's ICT Division.
Nagad has reshaped the country's MFS industry with one after another disruptive innovation and inspired confidence among people to embrace its products and services that are convenient and affordable. In this way, the state-owned mobile money carrier has established itself as the fastest unicorn startup in Bangladesh.
Presenting a keynote at the startup summit, State Minister for Information and Communication Technology Zunaid Ahmed Palak lauded Nagad's contribution to building a smart economy in Bangladesh.
Founder and Managing Director of Nagad Ltd. Tanvir A Mishuk said, "The way Digital Bangladesh is marching ahead we should have achieved the unicorn status much earlier. Now, our challenge is to take our company's valuation to USD 2 billion."
Increasing the valuation is not Nagad's main target, rather, it has embarked on its journey mainly to bring unbanked people under financial inclusion and get them used to digital payments, he also, adding, "We have already come a long way in meeting our target."
The way payments continue to evolve in keeping with people's changing lifestyle, there is no denying the fact that cashless is the future. Bangladesh government has taken many initiatives to attract people to digital payments. To complement the country's digital vision, Nagad is also working relentlessly to introduce new products and services required to accelerate the country's transition to a cashless society.
To grow into a complete financial solution, the MFS provider is going to establish a digital bank that will make available all financial services on a single platform. The mobile money carrier has already prepared itself accordingly.
"If we get the licence for digital bank, we will introduce collateral-free loans for small informal businesses who now take loans from moneylenders at 40% interest rate per day," said the Nagad MD.
If everything continues to go in the right direction, Bangladesh will emerge as a Smart Nation by 2041, envisioned by PM Sheikh Hasina.
About Nagad Ltd (https://www.nagad.com.bd/)
Nagad Limited is one of the leading MFS operators in Bangladesh's payment industry with 80 million registered customers and an average daily transaction of about USD 112 million. The digital payment platform, known as a successful public-private partnership between Bangladesh Postal Department and the private sector, was inaugurated in 2019 by Prime Minister Sheikh Hasina of the People's Republic of Bangladesh.
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SOURCE Nagad Limited | https://www.kxii.com/prnewswire/2023/07/31/nagad-becomes-bangladeshs-fastest-unicorn/ | 2023-07-31T05:29:08 | 0 | https://www.kxii.com/prnewswire/2023/07/31/nagad-becomes-bangladeshs-fastest-unicorn/ |
We hit an afternoon high of 102 degrees once again here in San Angelo. We have seen a few clouds develop throughout the area, but mostly sunny skies continued on our Sunday afternoon. Winds have been out of the south southeast around 10 mph. As we go into the evening our temps will gradually cool back to the low and mid 70s for our overnight lows. Skies will be mostly clear and winds will be out of the southeast at 5-10 mph though as we pass midnight they will shift out of the southwest.
As we start our workweek we will see another afternoon with temps mixing in the upper 90s and lower triple digits. A slight increase in our temps is possible. Skies will be mostly sunny once again with few clouds developing through the later afternoon hours. Winds will be out of the southwest at 5-10 mph and transitioning out of the south southeast as we transition into the evening. As we follow through into the evening our temps will gradually decrease back to the mid 70s for our overnight lows. Skies will be mostly clear through the night and our winds will continue out of the south southeast around 10 mph. | https://www.conchovalleyhomepage.com/weather/klst-evening-forecast-sunday-july-30th-2023-2/ | 2023-07-31T05:29:13 | 0 | https://www.conchovalleyhomepage.com/weather/klst-evening-forecast-sunday-july-30th-2023-2/ |
NANJING, China, July 31, 2023 /PRNewswire/ -- Nanjing Leads Biolabs Co., Ltd. (hereinafter referred to as "Leads Biolabs" or "Company") announced today that the National Medical Products Administration (NMPA) and the U.S. Food and Drug Administration (FDA) have approved its first-in-human Investigational New Drug (IND) applications for LBL-034, an anti-GPRC5D/CD3 bispecific antibody invented by Leads Biolabs with global intellectual property rights, for the treatment of relapsed/refractory multiple myeloma. Currently, no GPRC5D-targeting antibody has been approved for marketing.
This is a first-in-human, single-arm, multicenter, open-label, dose-escalation and expansion clinical study, and plans to enroll patients with relapsed/refractory multiple myeloma who have failed prior therapies including but not limited to at least one proteasome inhibitor (PI), one immunomodulator (IMiD) as well as other standard treatments. This study aims to evaluate the safety and tolerability of LBL-034, determine the recommended Phase II dose and assess its efficacy in patients with multiple myeloma.
"Despite recent progress and continuous advancements in multiple myeloma, the time between recurrences has been steadily decreasing, particularly as the number of treatment lines increases. This ultimately leads to emergence of relapsed or refractory multiple myeloma, reaffirming its status as an incurable malignant tumor that poses a serious threat to human life. In light of this challenging reality, the urgent need for more effective and innovative treatment options has never been more evident." said Dr. Charles Cai, Chief Medical Officer of Leads Biolabs, "LBL-034 adopts a unique molecular design, which enables the drug to specifically bind to GPRC5D-expressing tumor cells with high affinity, and reduces the risk of non-specific activation of T-cells, thereby enhancing anti-tumor efficacy and reducing potential risk of immunotoxicity. LBL-034 demonstrated robust anti-tumor activities and good safety profile in pre-clinical studies. We adhere to our tradition of innovation and aim to deliver an important, novel and effective treatment option for patients with poor prognosis of relapsed/refractory multiple myeloma."
About GPRC5D:
G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D) is a C-type 7-channel transmembrane receptor protein. GPRC5D is low expressed in normal human tissues but specifically overexpressed in multiple myeloma. The intensity of GPRC5D expression is an independent prognostic factor in multiple myeloma, and its overexpression is significantly associated with reduced overall survival. Therefore, GPRC5D may be an important potential target for the treatment of plasma cell diseases such as multiple myeloma.
About multiple myeloma:
Multiple myeloma is a malignant plasma cell disease caused by abnormal proliferation of clonal plasma cells, accounting for 10-15% of hematologic malignancies and about 1.4% of all malignancies. It is the second most common hematological malignancy in adults after non-Hodgkin's lymphoma and mostly occurs in the elderly. According to the data released by the World Health Organization (WHO), the number of new cases and deaths of multiple myeloma worldwide in 2020 were 176,000 and 117,000 respectively, and the number of new cases and deaths of multiple myeloma in China were 21,000 and 16,000 respectively. Currently, multiple myeloma is still an incurable malignant tumor, and the five-year survival rate of patients is approximately 24.8% in China, 33.3% in Japan, and 46.7% in the United States. In recent years, with the successful development of proteasome inhibitors (PIs), immunomodulatory drugs (IMiDs), selective nuclear output inhibitors, CD38-targeted antibodies, bispecific antibodies, and CAR-T cell therapies, the tumor response rate and survival prognosis have been significantly improved. However, multiple myeloma remains an unmet clinical need for more effective treatments.
About LBL-034:
LBL-034 is a humanized IgG1 subtype asymmetric bispecific antibody targeting both GPRC5D and CD3 and Leads Biolabs fully owns the worldwide intellectual property rights. LBL-034 induces T-cell-mediated killing of myeloma cells by redirecting CD3+ T-cells to myeloma cells expressing GPRC5D.
LBL-034 has the potential to be a transformative best-in-class GPRC5D-targeted immunotherapy for multiple myeloma. Clinical studies are planned to evaluate the safety and efficacy of LBL-034 in patients with relapsed/refractory multiple myeloma.
Nanjing Leads Biolabs Co., Ltd. is a clinical-stage biotechnology company founded in Nanjing by a team of senior U.S.-trained antibody drug developers. Since 2014, Leads Biolabs has been dedicated to the discovery and development of novel antibody drugs with independent intellectual property rights for the treatment of oncology and other major diseases of high unmet medical needs, particularly the challenges in cancer immunotherapy. Our extensive R&D pipeline consist of more than twenty novel tumor immunotherapy molecules based on monoclonal and bispecific antibody technology platforms. Leads Biolabs is committed to providing safe, effective, accessible and affordable new drugs to address the unmet needs of patients around the world.
For more information, please visit: https://www.leadsbiolabs.com
Business contact: bd@leadsbiolabs.com
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SOURCE LEADS BIOLABS | https://www.kxii.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ | 2023-07-31T05:29:14 | 0 | https://www.kxii.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ |
More experienced principals leave the profession at higher rates
WASHINGTON, July 31, 2023 /PRNewswire/ -- Roughly 1 in 10 (11 percent) public school principals left the profession between the 2020-21 and 2021-22 school years, according to data from the National Teacher and Principal Survey (NTPS) released today by the National Center for Education Statistics (NCES), the statistical center within the U.S. Department of Education's Institute of Education Sciences (IES).
"Principal attrition is higher in public schools than it was 5 years ago, and veteran public school leaders with more years of experience leave the profession at higher rates than those with less experience," said NCES Commissioner Peggy G. Carr. "Principals are critical supports for a school's teachers and learners, and the country needs leaders in every school who are committed to the success of each student. These data are a valuable snapshot for those at the district and state levels who must address the issue of principal turnover in their schools."
Approximately 80 percent of 2020-21 public school principals remained at the same school one year later ("stayers"), which was lower than the percentage of 2016-17 public school principals who were still at their school 1 year later (82 percent). Six percent of 2020-21 public school principals moved to a different school ("movers"), and 11 percent left the principalship ("leavers"). For private school principals in 2020-21, approximately 83 percent remained at the same school during the following school year, 2 percent moved to a different school, and 10 percent left the principalship.
Additionally, among 2020-21 public school principals who somewhat or strongly agreed they would leave the principalship as soon as possible if they could get a higher paying job (about 25 percent), approximately 73 percent stayed the following school year, while about 15 percent left the profession.
"These data are critical to understanding patterns of principal attrition," said NCES Associate Commissioner Chris Chapman. "We are able to observe how principal attrition has changed over the years, as well as how principal attrition and mobility vary based on characteristics of the principals and their schools."
The report released today includes selected findings from the Principal Follow-up Survey (PFS), a longitudinal component of the National Teacher and Principal Survey (NTPS), which is a nationally representative survey of public and private K-12 schools, principals, and teachers in the 50 states and the District of Columbia. Data were collected from January 2022 through June 2022. The sample included about 6,500 public school principals and about 1,800 private school principals, for a total sample size of about 8,300 principals.
The data were collected as a follow-up to the 2020-21 NTPS to provide attrition and mobility information about principals in K-12 public and private schools. The purpose was to ascertain how many principals from the 2020-21 school year still worked as a principal in the same school 1 year later ("stayer"), how many had moved to become a principal in another school ("mover"), and how many were no longer working as a principal ("leaver").
Key Findings
- Of all public school principals in 2020-21, 11 percent left the profession by the 2021-22 school year. This was higher than in 2016-17, when 10 percent of all public school principals had left the profession since 2015-16, but not measurably different from the 2012-13 school year, when 12 percent of all public school principals had left the profession since the previous school year, or from 2008-09, when 12 percent of all public schools had left the profession since the previous school year.
- Of all public school principals in 2020-21 with more than 10 years of experience as a principal at any school, 15 percent left the profession by the 2021-22 school year. Of those principals with 10 years or more experience as a principal in their current school, 16 percent left the profession.
- A higher percentage of school principals 55 years of age or older left the profession compared to principals between 45-54 years of age.
- Among the 9 percent of 2020-21 public school principals with a salary of less than $75,000, 76 percent remained at the same school during the 2021–22 school year, 7 percent moved to a different school, and 13 percent left the principalship.
- Among the 33 percent of 2020-21 public school principals with a salary of $115,000 or more, 81 percent remained at the same school during the 2021-22 school year, 6 percent moved to a different school, and 10 percent left the principalship.
- Among the 62 percent of 2020-21 private school principals with a salary of less than $75,000, 81 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 10 percent left the principalship.
- Among the 13 percent of 2020-21 private school principals with a salary of $115,000 or more, 85 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 8 percent left the principalship.
The National Center for Education Statistics, a principal agency of the U.S. Federal Statistical System, is the statistical center of the U.S. Department of Education and the primary federal entity for collecting and analyzing data related to education in the U.S. and other nations. NCES fulfills a congressional mandate to collect, collate, analyze, and report complete statistics on the condition and progress of American education; conduct and publish reports; and review and report on education activities internationally.
Follow NCES on Twitter, Facebook, LinkedIn, and YouTube and subscribe to the NCES Newsflash to receive email notifications when new data is released.
The Institute of Education Sciences (IES) is the independent and nonpartisan statistics, research, and evaluation arm of the U.S. Department of Education. Its mission is to provide scientific evidence on which to ground education practice and policy and to share this information in formats that are useful and accessible to educators, parents, policymakers, researchers, and the public.
CONTACT: Josh Delarosa, National Center for Education Statistics, ARIS.NCES@ed.gov
James Elias, Hager Sharp, jelias@hagersharp.com
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SOURCE National Center for Education Statistics | https://www.kxii.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ | 2023-07-31T05:29:21 | 0 | https://www.kxii.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ |
HANOI, Vietnam, July 31, 2023 /PRNewswire/ -- SeABank's stock (SSB) has been officially selected by the Ho Chi Minh City Stock Exchange (HOSE) to be included in the VN30-Index basket - an index representing the top 30 stocks with the highest market capitalization and liquidity listed on the HOSE.
At the end of the trading session on July 28, 2023, the closing price of SSB's stock was 29,700 VND per share, bringing SeABank's market capitalization to over 72,875 billion VND, equivalent to nearly 3.07 billion USD.
According to the press release, on July 17, 2023, HOSE announced the portfolio of stocks included in the VN30 and VN-Finlead indexes, which would be effective from August 7, 2023. SSB was chosen to be included in the VN30 basket as it met the requirements set by the HOSE Index Rules. With an average market capitalization of nearly 65,000 billion Vietnamese dongs over the past six months, SSB is one of the largest capitalized stocks among those not included in the previous VN30 basket.
Throughout its operations, SeABank prioritizes transparency by providing information to shareholders, partners, and customers, complying with legal regulations, and following the directives of the Government and the State Bank of Vietnam to stabilize the market, ensure smooth operations, and promote business activities, thereby contributing to the country's socio-economic development.
SeABank's stock (SSB) was officially listed on the HOSE on March 24, 2021, with a reference price of 16,800 Vietnamese dongs per share on its first trading day. It has consistently experienced stable growth since then. In June 2023, SeABank successfully issued shares for dividend payment and additional capital from shareholder funds (bonus shares) with a total ratio of 20.3% to increase its charter capital to 24,537 billion Vietnamese dong.
Previously, SSB was also added to the Morgan Stanley Capital Index (MSCI) Frontier Markets Index starting from March 1, 2023. According to experts, stocks included in the MSCI Frontier Markets Index may be targeted by ETF (Exchange Traded Fund) funds that track frontier market stocks. Some funds use this index as a reference for investment or replicate its portfolio.
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SOURCE SeABank | https://www.kxii.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ | 2023-07-31T05:29:27 | 0 | https://www.kxii.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ |
Monsoon season is finally blowing through the Valley putting Arizona utility companies on high alert for possible power outages.
Salt River Project (SRP) and Arizona Public Service (APS) prepare many months in advance for the summer. Both heat and monsoon storms pose a threat to the state’s utilities.
“Whether it’s making sure our power plants are able to generate the electricity or our transmission system is working in the best way possible,” SRP spokesperson Patty Garcia-Likens said.
Garcia-Likens said SRP also clears vegetation leading up to severe storms to limit obstructive objects from blowing into power lines.
“It’s the wind that does the most damage,” Garcia-Likens said.
Thousands of customers between SRP and APS lost power during the first monsoon storm of the season on Wednesday.
All outages were restored by the following day.
Both SRP and APS have similar restoration plans, including keeping personnel on stand-by when storms light up the radar.
“We have people and equipment spread throughout the Valley in order to respond quickly,” APS Distribution Operation Center Manager Wesley Horne said.
Crews immediately head into the operation center once outages occur to reroute power from unaffected areas to communities where the lines are down.
“You may see a power line down in your neighborhood, but you still have your lights on, that’s because we’re able to reroute that power pretty quickly from other areas of the territory,” Garcia-Likens said.
Linemen head to fix broken lines as soon as it’s safe to be outside.
“There are times where the storm does blow through rather quickly but can be violent,” Horne said. “We get right behind the storm, and we can start restoring power and cleaning up the mess as quickly as possible.”
Restoration response times vary depending on the severity of the storms and damage.
“We’re dealing with storms that may be unpredictable,” Horne said.
Garcia-Likens said it’s possible for homeowners to minimize the potential for damage by securing or bringing in loose outdoor items ahead of storms.
“We always encourage our customers to look around your back yard, look around your front yard at things that could caught up in the winds during these storms,” Garcia-Likens said.
Both SRP and APS recommend having a safety plan in place if the power goes out.
Up to Speed
Catch up on the latest news and stories on the 12News YouTube channel. Subscribe today. | https://www.12news.com/article/weather/monsoon/power-crews-on-call-247-during-monsoon-season/75-d361d6c8-4708-4b5a-9827-016a74290ea7 | 2023-07-31T05:30:45 | 1 | https://www.12news.com/article/weather/monsoon/power-crews-on-call-247-during-monsoon-season/75-d361d6c8-4708-4b5a-9827-016a74290ea7 |
Erratic winds challenge firefighters battling two major California blazes
MOJAVE NATIONAL PRESERVE, Calif. (AP) — A massive wildfire burning out of control in California’s Mojave National Preserve was spreading rapidly amid erratic winds, while firefighters reported progress against another major blaze to the southwest that prompted evacuations.
The York Fire that erupted Friday near the remote Caruthers Canyon area of the vast wildland preserve crossed the state line into Nevada on Sunday and sent smoke further east into the Las Vegas Valley.
Wind-driven flames 20 feet (6 meters) high in some spots charred more than 110 square miles (284 square kilometers) of desert scrub, juniper and Joshua tree woodland, according to an incident update. There was zero containment.
“The dry fuel acts as a ready ignition source, and when paired with those weather conditions it resulted in long-distance fire run and high flames, leading to extreme fire behavior,” the update said. No structures were threatened.
To the southwest, the Bonny Fire was holding steady at about 3.4 square miles (8.8 square kilometers) in rugged hills of Riverside County. More than 1,300 people were ordered to evacuate their homes Saturday near the community of Aguanga that is home to horse ranches and wineries.
Gusty winds and the chance of thunderstorms into Monday will heighten the risk of renewed growth, the California Department of Forestry and Fire Protection said in a statement.
One firefighter was injured in the blaze, which was 5% contained.
Copyright 2023 The Associated Press. All rights reserved. | https://www.kttc.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ | 2023-07-31T05:32:38 | 0 | https://www.kttc.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ |
Six migrant workers were struck Sunday afternoon by an SUV in a Walmart parking lot in North Carolina from what police are calling "an intentional assault with a vehicle."
"All six were transported to Atrium Health – Lincoln with various injuries. None of the injuries appear to be life threatening," the Lincolnton Police Department said in a Facebook post.
Police say they're still looking for the vehicle and driver involved in the incident, which they said took place at 1:17 pm ET. In the Facebook post, they describe the vehicle as an older model SUV with a luggage rack, and the driver as an older white male.
The motive for the attack is also still under investigation. Police told NPR via telephone late Sunday there is no further information.
Lincolnton is a small city of some 11,800 people located about an hour outside of Charlotte.
Copyright 2023 NPR. To see more, visit https://www.npr.org. | https://www.kcbx.org/npr-top-news/2023-07-30/an-suv-strikes-6-migrant-workers-in-walmart-parking-lot-in-north-carolina | 2023-07-31T05:33:16 | 1 | https://www.kcbx.org/npr-top-news/2023-07-30/an-suv-strikes-6-migrant-workers-in-walmart-parking-lot-in-north-carolina |
Erratic winds challenge firefighters battling two major California blazes
MOJAVE NATIONAL PRESERVE, Calif. (AP) — A massive wildfire burning out of control in California’s Mojave National Preserve was spreading rapidly amid erratic winds, while firefighters reported progress against another major blaze to the southwest that prompted evacuations.
The York Fire that erupted Friday near the remote Caruthers Canyon area of the vast wildland preserve crossed the state line into Nevada on Sunday and sent smoke further east into the Las Vegas Valley.
Wind-driven flames 20 feet (6 meters) high in some spots charred more than 110 square miles (284 square kilometers) of desert scrub, juniper and Joshua tree woodland, according to an incident update. There was zero containment.
“The dry fuel acts as a ready ignition source, and when paired with those weather conditions it resulted in long-distance fire run and high flames, leading to extreme fire behavior,” the update said. No structures were threatened.
To the southwest, the Bonny Fire was holding steady at about 3.4 square miles (8.8 square kilometers) in rugged hills of Riverside County. More than 1,300 people were ordered to evacuate their homes Saturday near the community of Aguanga that is home to horse ranches and wineries.
Gusty winds and the chance of thunderstorms into Monday will heighten the risk of renewed growth, the California Department of Forestry and Fire Protection said in a statement.
One firefighter was injured in the blaze, which was 5% contained.
Copyright 2023 The Associated Press. All rights reserved. | https://www.wibw.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ | 2023-07-31T05:33:19 | 1 | https://www.wibw.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ |
HONG KONG, July 31, 2023 /PRNewswire/ -- Akeso Inc. ("Akeso", the "Company"; 9926.HK), a commercial-stage biopharmaceutical company focused on developing and commercializing first-in-class and best-in-class innovative medicines globally, today announced that it is expected that the Company will record a profit of not less than RMB2.3 billion for the six months ended June 30, 2023. This is the first time for the Company to achieve half-year profits.
The turnaround from loss to profit during the Reporting Period was mainly attributable to:
- In respect of Ivonescimab (AK112, PD-1/VEGF) independently developed by the Company, the Company has entered into the collaborative and licensing agreement with Summit Therapeutics (details of which are set out in the announcement of the Company dated December 6, 2022). The Company has received the total upfront payment equivalent to US$500 million in full during the first quarter of 2023 (details of which are set out in the announcements of the Company dated January 26, 2023 and March 6, 2023). Part of such upfront payment was recognized as licensing fee income which significantly contributed to the revenue of the Company for the Reporting Period, and amounted to approximately RMB2.9 billion. The revenue recognition of the remaining portion of the upfront payment will be recognized as revenue in batches going forward.
- In respect of the Company's innovative product 开坦尼® (cadonilimab, PD-1/CTLA-4), since its launch in June 2022, it has recorded significant increase of the patients as well as product sales, which reflects the excellent clinical value of cadonilimab. In addition, 安尼可®(penpulimab, PD-1) also continued to contribute to the growth in the Company's product sales revenue during the Reporting Period.
- The Company has continued to optimise its cost management capabilities in a scientific and efficient way and has achieved better results in cost control while accelerating innovative products development and pipelines advancement.
About Akeso
Akeso (HKEX: 09926) is a commercial-stage biopharmaceutical company committed to the discovery, development, manufacturing, and commercialization of innovative medicines with high unmet medical needs worldwide. Founded in 2012, the Company has established a comprehensive in-house drug development platform (ACE Platform) and know-how, including R&D, clinical development, CMC (Chemistry, Manufacturing, and Controls), and commercialization capabilities.
With fully integrated multi-functional platform, Akeso is internally working on a robust pipeline of over 30 innovative assets in the fields of cancer, autoimmune disease, inflammation, metabolic disease, and other major therapeutic areas. 19 assets have entered clinical stage. Leveraging in-house developed bispecific platform technology ("Tetrabody technology"), the Company has advanced four potential first-in-class bispecific antibody drugs into market or clinical development, including cadonilimab (PD-1/CTLA-4), ivonescimab (PD-1/VEGF), PD-1/LAG-3, TIGIT/TGF-Beta bispecific antibodies. In June 2022, cadonilimab was approved by the NMPA and became the first commercialized PD-1 based bispecific drug globally. Another Akeso internally discovered and developed oncology product, penpulimab (a PD-1 antibody), was granted marketing approval in China in August 2021. In December 2022, the Company out-licensed breakthrough bispecific antibody, ivonescimab (PD-1/VEGF bi-specific antibody, AK112), with up to US$5 Billion total potential deal value to Summit Therapeutics for development and commercialization in the U.S., Canada, Europe, and Japan.
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SOURCE Akeso, Inc. | https://www.wibw.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ | 2023-07-31T05:33:31 | 1 | https://www.wibw.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ |
JONESBORO, Ga. — Parents were scrambling to find uniforms the weekend before school starts in Clayton County.
Some parents are saying it's harder this year due to price, color specifics, and other requirements from schools.
In Jonesboro, uniforms were flying off the shelves at Furniture, Linen, & More.
However, Ashley Neeland says she's been searching Facebook groups for other affordable options.
"It was difficult trying to budget and find things that are feasible for my pockets," Neeland said. "For the two shirts, I'm probably spending about 40-something dollars."
Neeland's children go to a charter school that requires polos of a specific color with the school logo.
"These shirts, they require logos. So, (I'm) not able to use what I have," Neeland said, "(I) pretty much have to start all the way over."
Neeland even tried to find ways to save a penny to no avail.
"I was hoping they could just find the logo," Neeland said, "And I could get it added on to the plain shirts because those are cheaper, but this school only has one vendor."
Other issues parents tell 11Alive about are that their kids wear adult sizes and can't fit into the clothes commonly sold in uniform stores.
King Traylor's child's school has specifics about the color polos students can wear, making finding it a tough task.
"It's very hard to find the gold," Traylor said. "It's been a little difficult at the popular places— like Walmart, K-Marts."
Kesha Matthews said she has to spend money at the beginning of the school year and during the year because her kids grow so fast.
"Over $100," Matthews said, "Yea, because they kind of go through them and then they grow."
Luckily, Clayton County Schools said there are resources. Parents can notify the school counselor and school social worker before and throughout the school year for help with uniforms. | https://www.11alive.com/article/news/education/clayton-county-parents-challenges-school-uniforms/85-2bd38c18-33cc-45ae-8c7f-07a5d50f2dad | 2023-07-31T05:33:35 | 1 | https://www.11alive.com/article/news/education/clayton-county-parents-challenges-school-uniforms/85-2bd38c18-33cc-45ae-8c7f-07a5d50f2dad |
SEOUL, South Korea, July 31, 2023 /PRNewswire/ -- J INTS BIO announced the successful dosing of the first patient in its global multi-center Phase 1/2 clinical study of 'JIN-A02' on 31st July at Severance Hospital, Seoul, Korea.
More clinical sites will follow suit, including seven more hospitals in Korea (National Cancer Center, Chungbuk National University Hospital, Samsung Seoul Hospital, Seoul National University Hospital, Seoul St. Mary's Hospital, St. Vincent Hospital, Asan Medical Center), two in the United States, and one in Thailand.
This global phase 1/2 clinical trial seeks to evaluate the safety, pharmacokinetics and anti-tumor activity of "JIN-A02" in advanced NSCLC patients carrying EGFR mutations.
'JIN-A02' is a novel orally administered 4th Generation EGFR TKI, which is highly selective for and strongly inhibits NSCLC with C797S double or triple mutations, showing efficacy even against intracranial tumors by exhibiting high blood-brain barrier penetrance.
Anna Jo, CEO of J INTS BIO, said, "We expect the positive results of 'JIN-A02' in the pre-clinical studies to translate to positive outcomes for patients in the clinical trial" adding that, "We hope also to proceed with the application for designation of orphan drug, and thereby quickly occupy the global NSCLC therapy market through conditional use."
About J INTS BIO
J INTS BIO is a bio company specialized in developing innovative anti-cancer and orphan drugs to realize the goal of changing lives and improving health for patients around the world. J INTS BIO's teams have prior multi-year experience in multinational pharmaceutical companies and CROs and track records in medical, regulatory affairs, drug discovery and development.
About 'JIN-A02'
'JIN-A02' is a novel orally administered 4th Generation EGFR TKI targeting C797S mutations in NSCLC. Although 1st, 2nd, and 3rd Generation EGFR TKIs have been used with some success, recurrence occurs in most patients including those on 3rd Generation TKIs such as Osimertinib. Currently, there are no approved therapies for patients who developed EGFR C797S mutations due to the use of 3rd Generation EGFR TKIs and with the high propensity of these cancers to metastasize to the brain, there is an urgent need to develop an effective drug with high blood-brain barrier permeability as well. 'JIN-A02', a novel oral EGFR TKI, which is effective against C797S double and triple mutations and have a high brain penetrance, is therefore expected to become the most promising Best-in-Class 4th-generation EGFR TKI in NSCLC patients with limited or no viable treatment options.
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SOURCE J INTS BIO | https://www.wibw.com/prnewswire/2023/07/31/j-ints-bio-novel-oral-4th-generation-egfr-tki-jin-a02-dosing-first-patient-global-multi-center-phase-12-clinical-study-began/ | 2023-07-31T05:33:38 | 1 | https://www.wibw.com/prnewswire/2023/07/31/j-ints-bio-novel-oral-4th-generation-egfr-tki-jin-a02-dosing-first-patient-global-multi-center-phase-12-clinical-study-began/ |
DHAKA, Bangladesh, July 31, 2023 /PRNewswire/ -- Nagad, a popular mobile money carrier based in Bangladesh, has emerged as a unicorn startup only in four years of its journey – the fastest in Bangladesh to reach this remarkable feat.
In recognition of the achievement, Tanvir A Mishuk, founder and managing director of Nagad Ltd., received the "Fastest to Unicorn Award" from Honourable Prime Minister of People's Republic of Bangladesh Sheikh Hasina at the inaugural ceremony of the two-day "Bangladesh Startup Summit 2023" in Hotel InterContinental Dhaka on 29 July 2023, hosted by Startup Bangladesh Ltd., the flagship venture capital company of the Government of Bangladesh's ICT Division.
Nagad has reshaped the country's MFS industry with one after another disruptive innovation and inspired confidence among people to embrace its products and services that are convenient and affordable. In this way, the state-owned mobile money carrier has established itself as the fastest unicorn startup in Bangladesh.
Presenting a keynote at the startup summit, State Minister for Information and Communication Technology Zunaid Ahmed Palak lauded Nagad's contribution to building a smart economy in Bangladesh.
Founder and Managing Director of Nagad Ltd. Tanvir A Mishuk said, "The way Digital Bangladesh is marching ahead we should have achieved the unicorn status much earlier. Now, our challenge is to take our company's valuation to USD 2 billion."
Increasing the valuation is not Nagad's main target, rather, it has embarked on its journey mainly to bring unbanked people under financial inclusion and get them used to digital payments, he also, adding, "We have already come a long way in meeting our target."
The way payments continue to evolve in keeping with people's changing lifestyle, there is no denying the fact that cashless is the future. Bangladesh government has taken many initiatives to attract people to digital payments. To complement the country's digital vision, Nagad is also working relentlessly to introduce new products and services required to accelerate the country's transition to a cashless society.
To grow into a complete financial solution, the MFS provider is going to establish a digital bank that will make available all financial services on a single platform. The mobile money carrier has already prepared itself accordingly.
"If we get the licence for digital bank, we will introduce collateral-free loans for small informal businesses who now take loans from moneylenders at 40% interest rate per day," said the Nagad MD.
If everything continues to go in the right direction, Bangladesh will emerge as a Smart Nation by 2041, envisioned by PM Sheikh Hasina.
About Nagad Ltd (https://www.nagad.com.bd/)
Nagad Limited is one of the leading MFS operators in Bangladesh's payment industry with 80 million registered customers and an average daily transaction of about USD 112 million. The digital payment platform, known as a successful public-private partnership between Bangladesh Postal Department and the private sector, was inaugurated in 2019 by Prime Minister Sheikh Hasina of the People's Republic of Bangladesh.
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SOURCE Nagad Limited | https://www.wibw.com/prnewswire/2023/07/31/nagad-becomes-bangladeshs-fastest-unicorn/ | 2023-07-31T05:33:44 | 0 | https://www.wibw.com/prnewswire/2023/07/31/nagad-becomes-bangladeshs-fastest-unicorn/ |
NANJING, China, July 31, 2023 /PRNewswire/ -- Nanjing Leads Biolabs Co., Ltd. (hereinafter referred to as "Leads Biolabs" or "Company") announced today that the National Medical Products Administration (NMPA) and the U.S. Food and Drug Administration (FDA) have approved its first-in-human Investigational New Drug (IND) applications for LBL-034, an anti-GPRC5D/CD3 bispecific antibody invented by Leads Biolabs with global intellectual property rights, for the treatment of relapsed/refractory multiple myeloma. Currently, no GPRC5D-targeting antibody has been approved for marketing.
This is a first-in-human, single-arm, multicenter, open-label, dose-escalation and expansion clinical study, and plans to enroll patients with relapsed/refractory multiple myeloma who have failed prior therapies including but not limited to at least one proteasome inhibitor (PI), one immunomodulator (IMiD) as well as other standard treatments. This study aims to evaluate the safety and tolerability of LBL-034, determine the recommended Phase II dose and assess its efficacy in patients with multiple myeloma.
"Despite recent progress and continuous advancements in multiple myeloma, the time between recurrences has been steadily decreasing, particularly as the number of treatment lines increases. This ultimately leads to emergence of relapsed or refractory multiple myeloma, reaffirming its status as an incurable malignant tumor that poses a serious threat to human life. In light of this challenging reality, the urgent need for more effective and innovative treatment options has never been more evident." said Dr. Charles Cai, Chief Medical Officer of Leads Biolabs, "LBL-034 adopts a unique molecular design, which enables the drug to specifically bind to GPRC5D-expressing tumor cells with high affinity, and reduces the risk of non-specific activation of T-cells, thereby enhancing anti-tumor efficacy and reducing potential risk of immunotoxicity. LBL-034 demonstrated robust anti-tumor activities and good safety profile in pre-clinical studies. We adhere to our tradition of innovation and aim to deliver an important, novel and effective treatment option for patients with poor prognosis of relapsed/refractory multiple myeloma."
About GPRC5D:
G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D) is a C-type 7-channel transmembrane receptor protein. GPRC5D is low expressed in normal human tissues but specifically overexpressed in multiple myeloma. The intensity of GPRC5D expression is an independent prognostic factor in multiple myeloma, and its overexpression is significantly associated with reduced overall survival. Therefore, GPRC5D may be an important potential target for the treatment of plasma cell diseases such as multiple myeloma.
About multiple myeloma:
Multiple myeloma is a malignant plasma cell disease caused by abnormal proliferation of clonal plasma cells, accounting for 10-15% of hematologic malignancies and about 1.4% of all malignancies. It is the second most common hematological malignancy in adults after non-Hodgkin's lymphoma and mostly occurs in the elderly. According to the data released by the World Health Organization (WHO), the number of new cases and deaths of multiple myeloma worldwide in 2020 were 176,000 and 117,000 respectively, and the number of new cases and deaths of multiple myeloma in China were 21,000 and 16,000 respectively. Currently, multiple myeloma is still an incurable malignant tumor, and the five-year survival rate of patients is approximately 24.8% in China, 33.3% in Japan, and 46.7% in the United States. In recent years, with the successful development of proteasome inhibitors (PIs), immunomodulatory drugs (IMiDs), selective nuclear output inhibitors, CD38-targeted antibodies, bispecific antibodies, and CAR-T cell therapies, the tumor response rate and survival prognosis have been significantly improved. However, multiple myeloma remains an unmet clinical need for more effective treatments.
About LBL-034:
LBL-034 is a humanized IgG1 subtype asymmetric bispecific antibody targeting both GPRC5D and CD3 and Leads Biolabs fully owns the worldwide intellectual property rights. LBL-034 induces T-cell-mediated killing of myeloma cells by redirecting CD3+ T-cells to myeloma cells expressing GPRC5D.
LBL-034 has the potential to be a transformative best-in-class GPRC5D-targeted immunotherapy for multiple myeloma. Clinical studies are planned to evaluate the safety and efficacy of LBL-034 in patients with relapsed/refractory multiple myeloma.
Nanjing Leads Biolabs Co., Ltd. is a clinical-stage biotechnology company founded in Nanjing by a team of senior U.S.-trained antibody drug developers. Since 2014, Leads Biolabs has been dedicated to the discovery and development of novel antibody drugs with independent intellectual property rights for the treatment of oncology and other major diseases of high unmet medical needs, particularly the challenges in cancer immunotherapy. Our extensive R&D pipeline consist of more than twenty novel tumor immunotherapy molecules based on monoclonal and bispecific antibody technology platforms. Leads Biolabs is committed to providing safe, effective, accessible and affordable new drugs to address the unmet needs of patients around the world.
For more information, please visit: https://www.leadsbiolabs.com
Business contact: bd@leadsbiolabs.com
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SOURCE LEADS BIOLABS | https://www.wibw.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ | 2023-07-31T05:33:50 | 1 | https://www.wibw.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ |
More experienced principals leave the profession at higher rates
WASHINGTON, July 31, 2023 /PRNewswire/ -- Roughly 1 in 10 (11 percent) public school principals left the profession between the 2020-21 and 2021-22 school years, according to data from the National Teacher and Principal Survey (NTPS) released today by the National Center for Education Statistics (NCES), the statistical center within the U.S. Department of Education's Institute of Education Sciences (IES).
"Principal attrition is higher in public schools than it was 5 years ago, and veteran public school leaders with more years of experience leave the profession at higher rates than those with less experience," said NCES Commissioner Peggy G. Carr. "Principals are critical supports for a school's teachers and learners, and the country needs leaders in every school who are committed to the success of each student. These data are a valuable snapshot for those at the district and state levels who must address the issue of principal turnover in their schools."
Approximately 80 percent of 2020-21 public school principals remained at the same school one year later ("stayers"), which was lower than the percentage of 2016-17 public school principals who were still at their school 1 year later (82 percent). Six percent of 2020-21 public school principals moved to a different school ("movers"), and 11 percent left the principalship ("leavers"). For private school principals in 2020-21, approximately 83 percent remained at the same school during the following school year, 2 percent moved to a different school, and 10 percent left the principalship.
Additionally, among 2020-21 public school principals who somewhat or strongly agreed they would leave the principalship as soon as possible if they could get a higher paying job (about 25 percent), approximately 73 percent stayed the following school year, while about 15 percent left the profession.
"These data are critical to understanding patterns of principal attrition," said NCES Associate Commissioner Chris Chapman. "We are able to observe how principal attrition has changed over the years, as well as how principal attrition and mobility vary based on characteristics of the principals and their schools."
The report released today includes selected findings from the Principal Follow-up Survey (PFS), a longitudinal component of the National Teacher and Principal Survey (NTPS), which is a nationally representative survey of public and private K-12 schools, principals, and teachers in the 50 states and the District of Columbia. Data were collected from January 2022 through June 2022. The sample included about 6,500 public school principals and about 1,800 private school principals, for a total sample size of about 8,300 principals.
The data were collected as a follow-up to the 2020-21 NTPS to provide attrition and mobility information about principals in K-12 public and private schools. The purpose was to ascertain how many principals from the 2020-21 school year still worked as a principal in the same school 1 year later ("stayer"), how many had moved to become a principal in another school ("mover"), and how many were no longer working as a principal ("leaver").
Key Findings
- Of all public school principals in 2020-21, 11 percent left the profession by the 2021-22 school year. This was higher than in 2016-17, when 10 percent of all public school principals had left the profession since 2015-16, but not measurably different from the 2012-13 school year, when 12 percent of all public school principals had left the profession since the previous school year, or from 2008-09, when 12 percent of all public schools had left the profession since the previous school year.
- Of all public school principals in 2020-21 with more than 10 years of experience as a principal at any school, 15 percent left the profession by the 2021-22 school year. Of those principals with 10 years or more experience as a principal in their current school, 16 percent left the profession.
- A higher percentage of school principals 55 years of age or older left the profession compared to principals between 45-54 years of age.
- Among the 9 percent of 2020-21 public school principals with a salary of less than $75,000, 76 percent remained at the same school during the 2021–22 school year, 7 percent moved to a different school, and 13 percent left the principalship.
- Among the 33 percent of 2020-21 public school principals with a salary of $115,000 or more, 81 percent remained at the same school during the 2021-22 school year, 6 percent moved to a different school, and 10 percent left the principalship.
- Among the 62 percent of 2020-21 private school principals with a salary of less than $75,000, 81 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 10 percent left the principalship.
- Among the 13 percent of 2020-21 private school principals with a salary of $115,000 or more, 85 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 8 percent left the principalship.
The National Center for Education Statistics, a principal agency of the U.S. Federal Statistical System, is the statistical center of the U.S. Department of Education and the primary federal entity for collecting and analyzing data related to education in the U.S. and other nations. NCES fulfills a congressional mandate to collect, collate, analyze, and report complete statistics on the condition and progress of American education; conduct and publish reports; and review and report on education activities internationally.
Follow NCES on Twitter, Facebook, LinkedIn, and YouTube and subscribe to the NCES Newsflash to receive email notifications when new data is released.
The Institute of Education Sciences (IES) is the independent and nonpartisan statistics, research, and evaluation arm of the U.S. Department of Education. Its mission is to provide scientific evidence on which to ground education practice and policy and to share this information in formats that are useful and accessible to educators, parents, policymakers, researchers, and the public.
CONTACT: Josh Delarosa, National Center for Education Statistics, ARIS.NCES@ed.gov
James Elias, Hager Sharp, jelias@hagersharp.com
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SOURCE National Center for Education Statistics | https://www.wibw.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ | 2023-07-31T05:33:57 | 0 | https://www.wibw.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ |
HANOI, Vietnam, July 31, 2023 /PRNewswire/ -- SeABank's stock (SSB) has been officially selected by the Ho Chi Minh City Stock Exchange (HOSE) to be included in the VN30-Index basket - an index representing the top 30 stocks with the highest market capitalization and liquidity listed on the HOSE.
At the end of the trading session on July 28, 2023, the closing price of SSB's stock was 29,700 VND per share, bringing SeABank's market capitalization to over 72,875 billion VND, equivalent to nearly 3.07 billion USD.
According to the press release, on July 17, 2023, HOSE announced the portfolio of stocks included in the VN30 and VN-Finlead indexes, which would be effective from August 7, 2023. SSB was chosen to be included in the VN30 basket as it met the requirements set by the HOSE Index Rules. With an average market capitalization of nearly 65,000 billion Vietnamese dongs over the past six months, SSB is one of the largest capitalized stocks among those not included in the previous VN30 basket.
Throughout its operations, SeABank prioritizes transparency by providing information to shareholders, partners, and customers, complying with legal regulations, and following the directives of the Government and the State Bank of Vietnam to stabilize the market, ensure smooth operations, and promote business activities, thereby contributing to the country's socio-economic development.
SeABank's stock (SSB) was officially listed on the HOSE on March 24, 2021, with a reference price of 16,800 Vietnamese dongs per share on its first trading day. It has consistently experienced stable growth since then. In June 2023, SeABank successfully issued shares for dividend payment and additional capital from shareholder funds (bonus shares) with a total ratio of 20.3% to increase its charter capital to 24,537 billion Vietnamese dong.
Previously, SSB was also added to the Morgan Stanley Capital Index (MSCI) Frontier Markets Index starting from March 1, 2023. According to experts, stocks included in the MSCI Frontier Markets Index may be targeted by ETF (Exchange Traded Fund) funds that track frontier market stocks. Some funds use this index as a reference for investment or replicate its portfolio.
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SOURCE SeABank | https://www.wibw.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ | 2023-07-31T05:34:04 | 1 | https://www.wibw.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ |
LOS ANGELES — When viewed through a wide lens, renters across the U.S. finally appear to be getting some relief, thanks in part to the biggest apartment construction boom in decades.
Median rent rose just 0.5% in June, year over year, after falling in May for the first time since the pandemic hit the U.S. Some economists project U.S. rents will be down modestly this year after soaring nearly 25% over the past four years.
A closer look, however, shows the trend will likely be little comfort for many U.S. renters who’ve had to put an increasing share of their income toward their monthly payment. Renters in cities such as Cincinnati and Indianapolis are still getting hit with increases of 5% or more. Much of the new construction is located in just a few metro areas, and many of the new units are luxury apartments, which rent for well north of $2,000.
Median U.S. rent has risen to $2,029 this June from $1,629 in June 2019, according to rental listings company Rent, which tracks rents in 50 of the largest U.S. metropolitan areas. Demand for apartments exploded during the pandemic as people who could work remotely sought more space or decided to relocate to another part of the country.
The steep rent increases have left tenants like Melissa Lombana, a high school teacher who lives in the South Florida city of Miramar, with progressively less income to spend on other needs.
The rent on her one-bedroom apartment jumped 13% last year to $1,700. It climbed another 6% to $1,800 this month when she renewed her lease.
“Even the $1,700 was a stretch for me,” said Lombana, 43, who supplements her teaching income with a side job doing educational testing. “In a year, I will not be able to afford living here at all.”
Lombana’s rent is now gobbling up nearly half her monthly income. That puts her in a category referred to as “cost-burdened” by the U.S. Department of Housing and Urban Development, denoting households that pay 30% or more of their income toward rent. Last year, the average rent-to-income ratio per household rose to 30%. This March, it was 29.6%.
Lombana hasn’t had any luck finding a more affordable apartment. While South Florida is one of the metropolitan areas seeing a rise in apartment construction, the units are mostly high-end and not a viable option.
That scenario is playing out across the nation. Developers are rushing to complete projects that were green-lit during the pandemic-era surge in demand for rentals or left in limbo by delays in supplies of fixtures and building materials. Nearly 1.1 million apartments are currently under construction, according to the commercial real estate tracker CoStar, a pace not seen since the 1970s.
Increasing the supply of apartments tends to moderate rent increases over time and can give tenants more options on where to live. But more than 40% of the new rentals to be completed this year will be concentrated in about 10 high job growth metropolitan areas, including Austin, Nashville, Denver, Atlanta and New York, according to Marcus & Millichap. In many areas, the boost to overall inventory will be barely noticeable.
Even within metros where there’ll be a notable increase in available apartments, such as Nashville, most of it will be in the luxury category, where rents average $2,270, nationally. Some 70% of the new rental inventory will be the luxury class, said Jay Lybik, national director of multifamily analytics at CoStar.
That will leave most tenants unlikely to see a big enough reduction in rent to make a difference, industry experts and economists say.
“I think we’re in a period of rent flattening for 12 or 18 months, but it’s certainly not a big rent decline,” said Hessam Nadji, CEO of commercial real estate firm Marcus & Millichap.
“We’re building a multi-decade record number of units,” Nadji said. “It’s going to cause some softening and some pockets of overbuilding, but it’s not going to fundamentally resolve the housing shortage or the affordability problem for renters across the U.S.”
The surge in rents has made it difficult for workers to keep up with inflation despite solid wage gains the past few years and exacerbated a long-term trend. Between 1999 and 2022, U.S. rents soared 135%, while income grew 77%, according to data from Moody’s Analytics.
Realtor.com is forecasting that rents will drop an average of 0.9% this year. But while down nationally, rents are still rising in many markets around the country, especially those where hiring remains robust.
In the New York metro area, the median rent climbed 4.7% in June from a year earlier to $2,899, according to Realtor.com. In the Midwest, rents surged 5.6% in the Cincinnati metro area to $1,188, and 6.9% to $1,350 in the Indianapolis metro area.
The current spike in apartment construction alone isn’t going to be enough to address how costly renting has become for many Americans.
“For the rest of the 2020s rents will continue to grow because millennials are such a big generation and we’re very much in the hole in terms of building housing for that generation,” said Daryl Fairweather, chief economist at Redfin. “It will take many good years of new construction to build adequate housing for millennials.”
The bigger challenge is building more work force housing, because the cost of land, labor and navigating the government approval process incentivize developers to put up luxury apartments buildings.
Expanding the supply of modestly priced rentals would help alleviate the strain from so many new apartments targeting renters with high incomes, “although additional subsidies will be needed to make housing affordable to households with the lowest incomes,” researchers at Harvard University’s Joint Center for Housing Studies wrote in a recent report.
Despite the overall pullback in U.S. rents, Joey Di Girolamo, in Pembroke Pines, Florida, worries that he’ll face more sharp rent increases in coming years.
Last year, the web designer left a two-bedroom, two-bath townhome he rented for $2,200 a month to avoid a $600 a month increase. This year, his rent went up by $200, a nearly 10% jump.
“That blew me away,” said Di Girolamo, 50. “I’m just kind of dreading what it’s going to be like next year, but especially 3 or 4 years from now.” | https://www.kens5.com/article/money/some-renters-may-get-relief-from-biggest-apartment-construction-boom-in-decades-but-not-all-landlord-tenant/507-2fda036b-0bb9-449c-8000-bc5b9c73122e | 2023-07-31T05:34:36 | 1 | https://www.kens5.com/article/money/some-renters-may-get-relief-from-biggest-apartment-construction-boom-in-decades-but-not-all-landlord-tenant/507-2fda036b-0bb9-449c-8000-bc5b9c73122e |
BOWIE, Maryland — With back to school season right around the corner, you may be wondering is it too late to pursue a higher education? A 72-year-old woman from Maryland is proving it's never too late.
Diane Allen Tate went back to school at age 65, but kept her education journey a secret from even her family and friends for the last seven years.
In those years, Tate served as a primary caregiver for her mother while secretly balancing higher education classes online.
But now the secret is out of the bag--and Tate's family couldn't be prouder of her.
Tate graduated with honors and a PsyD in Behavioral Health Leadership from Walden University on Saturday.
This was the first time Tate attended an official graduation despite having an undergraduate and masters degree. She gradated Boston University in 1972 with a psychology degree. Three years later, she took home a masters degree in development psychology from Boston University. But because of the Vietnam War and her romantic pursuits, Tate was unable to walk across the stage.
Dr. Tate's family shared a few photos from the celebration, which they said they wanted to "make a big deal out of" since she kept it a secret for so long. | https://www.kens5.com/article/news/community/senior-citizen-receives-doctorate-keeps-education-secret-from-family/65-d1b76026-8705-42ba-a4d0-a6288ce7c023 | 2023-07-31T05:34:42 | 1 | https://www.kens5.com/article/news/community/senior-citizen-receives-doctorate-keeps-education-secret-from-family/65-d1b76026-8705-42ba-a4d0-a6288ce7c023 |
COLLEGE STATION, Texas — Nearly 3.5 hours after the Texas A&M Board of Regents began a special meeting Sunday, they picked a new interim president and made a decision on potential settlement claims, according to the university.
Mark Welsh III, Dean of A&M's Bush School, was named the interim president.
The board also OK'd settlement negotiations with Dr. Kathleen McElroy, a professor at the University of Texas, after a botched hiring process that would have made her the new director of the journalism school, according to a Bryan-College Station Eagle report. Texas A&M initially celebrated the hiring of McElroy but then watered down her contract after some people criticized her prior work on diversity and inclusion. She ultimately turned down the job.
Also, Katherine Banks, Texas A&M's president at the time, would resign over the fallout.
The board also reportedly will release finding from the General Counsel's Office investigation into the hiring to the general public.
Sunday night's meeting immediately went into closed session and no part of it was streamed online.
Who is Welsh?
- Has been acting president since July 21, 2023
- Previously was dean of Bush School of Government and Public Service
- Retired from U.S. Air Force
- Has a BS from U.S. Air Force Academy and Masters of Science in computer resource management from Webster University.
- Became 20th Chief of Staff of the Air Force in August of 2012. | https://www.kens5.com/article/news/education/texas-am-new-interim-president/285-e6e7e0ab-232e-4084-8fc6-3bff5db4507f | 2023-07-31T05:34:48 | 0 | https://www.kens5.com/article/news/education/texas-am-new-interim-president/285-e6e7e0ab-232e-4084-8fc6-3bff5db4507f |
SAN ANTONIO — The family of the 4-year-old girl SAPD said drowned in a pool Wednesday night on the Southwest side is raising money to pay for the funeral.
The family held a plate sale Sunday afternoon at their family business, Little Fish Factory.
Across the restaurant’s counter were photos of Jazida Hernandez Cervera.
“We’re trying to stay strong, for her,” Cassandra Cervera said.
Cassandra and Terri Cervera are Jazida’s aunts. They said Jazida’s mother was at work Wednesday night when she got a call that her daughter had gone missing.
“She has to work, she’s a single mom with two children,” Terri Cervera said. “She’d rather die than her own daughter.”
San Antonio Police said the family, who was watching the four-year-old in a backyard, called them around 8 p.m. that night. Police said the family told them Jazida had only been missing for 30 minutes before they called.
Once police got to the home off Ocean Gate, they found her face down in an above the ground pool. She was pronounced dead at the hospital, according to police.
“She was mama’s best friend,” Cassandra Cervera said. “Mama loved her very much took care of her very much.”
The family is now focused on planning and paying for a funeral. Along with the plate sale, they set up a GoFundMe.
“She’s going to need the prayers for many many years to come, that’s her only daughter,” Terri Cervera said.
Police said the drowning appears to be accidental, but they are investigating. So far, no charges have been filed. | https://www.kens5.com/article/news/local/family-four-police-drowned-pool-funeral/273-98a2fc60-6a93-4aab-98d1-8b9aa29c6dee | 2023-07-31T05:34:54 | 0 | https://www.kens5.com/article/news/local/family-four-police-drowned-pool-funeral/273-98a2fc60-6a93-4aab-98d1-8b9aa29c6dee |
SAN ANTONIO — The owner of San Antonio’s only brick and mortar magic shop is looking to retire, which leaves the fate of the store uncertain if he can’t find someone to buy it.
He'll be the first to admit: it's a fun job.
"It's a very unique art.” Julio said, “It can be fun, it can be mysterious."
But he stresses that it is still a job, and that it comes with its own unique challenges.
“I don't think I ever took a solid weeks’ vacation off,” he said.
Julio announced he was putting the business up for sale on July 27th. Posting the announcement to the store’s Facebook page and its website.
“I'm ready to retire,” he said. “I don’t feel so bad that I have to. But I want to.”
Julio got into the magic business in 1997 after another magic store went up for sale. He said the owner showed him a simple trick that blew him away.
He didn't buy that shop, but months later it did inspire him to open his own. He said he set his shop apart by having it open and accessible. He said many of the stores at the time had all of the tricks hidden away, so people wouldn't be able to buy something unless they already knew what they were looking for.
In 2018, Julio was featured on Great Day SA. When Paul Mireles asked him about the future of his shop, Julio said to keep going until "whenever." Whenever, it appears, has arrived.
"It's been amazing for our family,” said Julio’s Son David Ramirez.
“I mean, I started when I was 12, I was demoing. I had that was like my first job. He was paying me."
David said he was conflicted when he found out his dad put the store up for sale.
know, my dad's been doing it for a long time,” he said. “And so, it's kind of his time."
he said taking over the shop himself has crossed his mind, but he worries juggling it with his full-time job and his six-month-old baby will be too much to handle.
"There's plenty of thoughts that kind of go through my mind," said David. "Haven’t got a chance to really kind of vet them or, ... even get close to making this sort of decision on that."
"for me, it was great, it was a turning point,” said JCR Magic regular Kevin Bryan.
Bryan has been coming to Julio's store for twenty years. The Vietnam Veteran said performing magic has helps him with his PTSD.
"I got to where I could interact with people by performing. By becoming…” Bryan paused to put on a brown bowler hat before deepening his voice.
“…Professor Baffle," he proclaimed.
For Professor Baffle, the Ramirez's and everyone involved, the future of JCR Magic remains an open question. But Julio is hopeful that the magic won't have to disappear.
"Hopefully I can get a buyer that will continue the magic shop in San Antonio," he said. | https://www.kens5.com/article/news/local/owner-san-antonios-magic-shop-buyer/273-e2133863-4129-446c-b4f5-bf99fee05984 | 2023-07-31T05:35:00 | 1 | https://www.kens5.com/article/news/local/owner-san-antonios-magic-shop-buyer/273-e2133863-4129-446c-b4f5-bf99fee05984 |
SAN ANTONIO — For so many families, access to child care isn't easy and it isn't cheap.
This is especially true for those in the military.
Too often, military families are asked to front thousands of dollars for child care because there's not enough room on base.
As KENS 5 learned, a new amendment aims to ease this burden.
To gain better perspective on how tough child care is to find for military families, Shealynn O'Bar shared her story. She just moved with her family from North Dakota to San Antonio where her husband is stationed at Randolph Air Force Base.
"We found out we were coming here in March," said O'Bar, who immediately began looking for child care for her 7-month-old daughter.
O'Bar had four months to find a day care in San Antonio, preferably where her husband would be stationed.
"We put our daughter on the CDC, the Child Development Center on base in March. They gave us a timeframe of December, January of next year. So we have to wait a year for day care," said O'Bar, who, like her husband, has a full-time job.
Child care is a neccesity for the O'Bar family, so Shealynn expanded her search.
"We called about 20 day cares and every single daycare recalled had a year to two year waitlist. So we we were like, what do we do?"
She says by using Child Care Aware of America, her child care options are limited. To pay the same price as she would on base, only certain day cares within a 15-mile radius from Randolph qualify.
"We looked into day care outside of San Antonio, about 45 minutes away, but that would have been directly out of pocket," O'Bar explained. "The day cares we were finding were like $1,500 a month. That's just not feasible for a military family."
After a week without child care and her husband missing mandatory work functions, O'Bar was able to find a day care where she's paying the same amount as she would on the military base.
According to the Department of Defense's 2020 Report to Congress on Child Development Programs: 9,000 military children are currently stuck on a waitlist, 135 child care facilities are in “Poor” or “Failing” condition due to deferred maintenance and 124 priority Child Development Center projects don’t have funds to move forward.
"78.8% of our respondents had a hard time accessing childcare," said Shannon Razsadin, President & Executive Director of the Military Family Advisory Network. The organization conducted a survey in 2021, inquiring military families about obstacles they face with child care.
Razsadin says too often families are forced to miss job commitments for child care.
"Often also, we're living in locations where we don't have an extended network of support, so we don't have grandparents and family and friends nearby who can lean in and pinch hit for us," she said.
July 11, Congressman Joaquin Castro and Greg Casar introduced an amendment to the National Defense Authorization Act (NDAA).
It would give the Department of Defense more flexibility to reallocate Congressionally-appropriated program and weapons funding that exceeds the Pentagon's budget request to expand child care programs for military families.
The U.S. House of Representatives passed the NDAA. The Senate passed its own version of the bill, too. What happens next is lawmakers must negogiate to come up with a new version that can pass both chambers. | https://www.kens5.com/article/news/national/military-news/funding-for-military-child-care-programs/273-9d4b888f-2d56-448e-9642-d85f9fe18f31 | 2023-07-31T05:35:06 | 1 | https://www.kens5.com/article/news/national/military-news/funding-for-military-child-care-programs/273-9d4b888f-2d56-448e-9642-d85f9fe18f31 |
CALLAWAY, Fla. — One Florida woman is missing a piece of her ear after getting into a fight over alleged stolen vape pens and alcohol, according to the Bay County Sheriff's Office.
Macy Regan, 23, was attending a Fourth of July party in Callaway, Florida, when a fight involving several men broke out in the yard, deputies said. She then attempted to leave the party to walk back home, which was a few doors down the street.
As she was leaving, 18-year-old Dixie Stiles confronted her and accused her of stealing alcohol and vape pens, deputies said.
Regan then reportedly pulled out a 9MM handgun from her waistband, but Stiles was able to shove it away — a fight then ensured between the two Florida women. As they were fighting, deputies said Regan bit the top of Stiles’ ear off.
Stiles’ ear was unable to be re-attached, deputies said.
Both women face charges and an investigation into this incident is ongoing. | https://www.kens5.com/article/news/regional/florida-woman-bites-ear-off/67-82445da9-dcd3-4175-b886-24045b69de8c | 2023-07-31T05:35:12 | 0 | https://www.kens5.com/article/news/regional/florida-woman-bites-ear-off/67-82445da9-dcd3-4175-b886-24045b69de8c |
When viewed through a wide lens, renters across the United States finally appear to be getting some relief, thanks in part to the biggest apartment construction boom in decades.
Median rent rose just 0.5% in June, year over year, after falling in May for the first time since the pandemic hit the U.S. Some economists project U.S. rents will be down modestly this year after soaring nearly 25% over the past four years.
A closer look, however, shows the trend will likely be little comfort for many U.S. renters who’ve had to put an increasing share of their income toward their monthly payment. Renters in cities such as Cincinnati and Indianapolis are still getting hit with increases of 5% or more. Much of the new construction is located in just a few metro areas, and many of the new units are luxury apartments, which rent for well north of $2,000.
Median U.S. rent has risen to $2,029 this June from $1,629 in June 2019, according to rental listings company Rent, which tracks rents in 50 of the largest U.S. metropolitan areas. Demand for apartments exploded during the pandemic as people who could work remotely sought more space or decided to relocate to another part of the country.
The steep rent increases have left tenants like Melissa Lombana, a high school teacher who lives in the South Florida city of Miramar, with progressively less income to spend on other needs.
The rent on her one-bedroom apartment jumped 13% last year to $1,700. It climbed another 6% to $1,800 this month when she renewed her lease.
“Even the $1,700 was a stretch for me,” said Lombana, 43, who supplements her teaching income with a side job doing educational testing. “In a year, I will not be able to afford living here at all.”
Lombana’s rent is now gobbling up nearly half her monthly income. That puts her in a category referred to as “cost-burdened” by the U.S. Department of Housing and Urban Development, denoting households that pay 30% or more of their income toward rent. Last year, the average rent-to-income ratio per household rose to 30%. This March, it was 29.6%.
Lombana hasn’t had any luck finding a more affordable apartment. While South Florida is one of the metropolitan areas seeing a rise in apartment construction, the units are mostly high-end and not a viable option.
That scenario is playing out across the nation. Developers are rushing to complete projects that were green-lit during the pandemic-era surge in demand for rentals or left in limbo by delays in supplies of fixtures and building materials. Nearly 1.1 million apartments are currently under construction, according to the commercial real estate tracker CoStar, a pace not seen since the 1970s.
Increasing the supply of apartments tends to moderate rent increases over time and can give tenants more options on where to live. But more than 40% of the new rentals to be completed this year will be concentrated in about 10 high job growth metropolitan areas, including Austin, Nashville, Denver, Atlanta and New York, according to Marcus & Millichap. In many areas, the boost to overall inventory will be barely noticeable.
Even in metros where there’ll be a notable increase in available apartments, such as Nashville, most of it will be in the luxury category, where rents average $2,270, nationally. Some 70% of the new rental inventory will be the luxury class, said Jay Lybik, national director of multifamily analytics at CoStar.
That will leave most tenants unlikely to see a big enough reduction in rent to make a difference, industry experts and economists say.
“I think we’re in a period of rent flattening for 12 or 18 months, but it’s certainly not a big rent decline,” said Hessam Nadji, CEO of commercial real estate firm Marcus & Millichap.
“We’re building a multi-decade record number of units,” Nadji said. “It’s going to cause some softening and some pockets of overbuilding, but it’s not going to fundamentally resolve the housing shortage or the affordability problem for renters across the U.S.”
The surge in rents has made it difficult for workers to keep up with inflation despite solid wage gains the past few years and exacerbated a long-term trend. Between 1999 and 2022, U.S. rents soared 135%, while income grew 77%, according to data from Moody’s Analytics.
Realtor.com is forecasting that rents will drop an average of 0.9% this year. But while down nationally, rents are still rising in many markets around the country, especially those where hiring remains robust.
In the New York metro area, the median rent climbed 4.7% in June from a year earlier, to $2,899, according to Realtor.com. In the Midwest, rents surged 5.6% in the Cincinnati metro area, to $1,188, and 6.9%, to $1,350, in the Indianapolis metro area.
The current spike in apartment construction alone isn’t going to be enough to address how costly renting has become for many Americans.
“For the rest of the 2020s rents will continue to grow because millennials are such a big generation and we’re very much in the hole in terms of building housing for that generation,” said Daryl Fairweather, chief economist at Redfin. “It will take many good years of new construction to build adequate housing for millennials.”
The bigger challenge is building more work force housing, because the cost of land, labor and navigating the government approval process incentivize developers to put up luxury apartments buildings.
Expanding the supply of modestly priced rentals would help alleviate the strain from so many new apartments targeting renters with high incomes, “although additional subsidies will be needed to make housing affordable to households with the lowest incomes,” researchers at Harvard University’s Joint Center for Housing Studies wrote in a recent report.
Despite the overall pullback in U.S. rents, Joey Di Girolamo, in Pembroke Pines, Florida, worries that he’ll face more sharp rent increases in coming years.
Last year, the web designer left a two-bedroom, two-bath townhome he rented for $2,200 a month to avoid a $600 a month increase. This year, his rent went up by $200, a nearly 10% jump.
“That blew me away,” said Di Girolamo, 50. “I’m just kind of dreading what it’s going to be like next year, but especially 3 or 4 years from now.”
Please enable JavaScript to view this content. | https://www.ibj.com/articles/some-renters-might-get-relief-from-biggest-apartment-construction-boom-in-decades | 2023-07-31T05:35:30 | 0 | https://www.ibj.com/articles/some-renters-might-get-relief-from-biggest-apartment-construction-boom-in-decades |
RB Jonathan Taylor refutes reports that he suffered back injury away from Colts
Colts running back Jonathan Taylor issued a stark rebuttal Sunday night to multiple reports that he’d suffered a back injury working out while away from the team this offseason, an injury that could lead to Indianapolis placing him on the non-football injury list.
If placed on NFI, the Colts could withhold Taylor’s pay under the NFL’s collective bargaining agreement.
Taylor, who has not spoken publicly about his desire for a contract extension since mid-June and hasn’t been available to the media since training camp began, broke his silence in response to the report.
Doyel:Jonathan Taylor joins Andrew Luck, Victor Oladipo as star athletes receiving bad advice
“1) Never had a back pain,” Taylor wrote on Twitter. “2.) Never reported back pain. … Not sure who ‘sources’ are, but find new ones.”
Taylor reported to training camp Tuesday and was placed on the active/physically unable to perform list, a designation for players who suffered an injury while playing, practicing or training with their teams.
Players on the PUP list still get paid.
A player on the NFI list is “not entitled to receive his salary, and his contract will continue to run while in such status,” according to the NFL. “That said, the team and player can negotiate a rate of payment for the player on this list.”
Fox59 and ESPN reported Sunday night that Taylor had suffered a back injury while working out away from the team this offseason, and that the Colts were contemplating moving the running back to NFI, a decision that would be a significant escalation in the increasingly tense standoff between Taylor and the team over the state of his contract.
More:Jim Irsay holds hour-long bus chat with Jonathan Taylor amid contract and trade requests
Taylor is headed into the final year of his rookie contract, and NFL teams typically try to extend key players before that final season begins. Indianapolis has extended several other drafted stars before the final season of their rookie contracts started in recent years, including left guard Quenton Nelson, linebacker Shaquille Leonard, right tackle Braden Smith, center Ryan Kelly and another running back, former Colt Nyheim Hines.
But Colts owner Jim Irsay has made it clear this week that the team does not plan to sign Taylor until after the season, and the team has not entered contract negotiations with the running back who has rushed for 3,841 yards and 33 touchdowns in his first three seasons with the team.
Taylor responded by requesting a trade last week.
The two men met Saturday night in Irsay’s bus while the rest of the team practiced, but no resolution to the situation was reached, and news of Taylor’s trade request broke shortly after the end of Irsay’s comments to reporters. With news of Taylor’s trade request public, Irsay responded by stating that the Colts would not trade Taylor, either now or in October. | https://www.indystar.com/story/sports/nfl/colts/2023/07/30/colts-jonathan-taylor-refutes-reports-of-injury-suffered-away-from-team/70495992007/ | 2023-07-31T05:35:38 | 1 | https://www.indystar.com/story/sports/nfl/colts/2023/07/30/colts-jonathan-taylor-refutes-reports-of-injury-suffered-away-from-team/70495992007/ |
NEWPORT TOWNSHIP, LUZERNE COUNTY (WBRE/WYOU) — Investigators are looking into a crash between a car and ATV in Luzerne County.
A viewer provided 28/22 News video of the scene on the 100 block of Alden Road in Alden, Newport Township.
Luzerne County Communications Center told 28/22 News first responders from Nanticoke and Newport were dispatched around 7:30 p.m. Sunday evening for a reported hit-and-run.
Someone on the ATV was injured, and the car that collided with the vehicle fled the scene.
The extent of the injuries is unknown. 28/22 News left messages with Nanticoke police and fire departments and are waiting to hear back. | https://www.pahomepage.com/news/first-responders-rush-to-newport-township-crash/ | 2023-07-31T05:35:38 | 0 | https://www.pahomepage.com/news/first-responders-rush-to-newport-township-crash/ |
TUPELO, Miss. - A local barbershop helped kids start school in style Sunday. Vanzant Barbershop Lounge gave free haircuts for kids from 1 to 4PM.
Barbers donated a total of 50 free cuts. Owner Steven Vanzant said inflation has put a dent in a lot of family budgets. He wanted to relieve some stress for parents and boost kids’ confidence before they hit the halls.
“A lot of parents are struggling right now because we're in a trying time with the economy,” Vanzant said. “And for us to give back, It's really important just to help out for them, you know, knock a couple of dollars off their budget so they can get other things for their kids. So, if we get haircuts for the kids for free, maybe that'll give confidence to the young man as well and shorten the budget for the parents.”
Children and their parents left the barbershop with smiles and fresh fades. | https://www.wtva.com/news/local-barbershop-donates-free-haircuts-to-children-for-back-to-school/article_4f6fb1fa-2f25-11ee-8a8c-7f310f550bde.html | 2023-07-31T05:35:38 | 0 | https://www.wtva.com/news/local-barbershop-donates-free-haircuts-to-children-for-back-to-school/article_4f6fb1fa-2f25-11ee-8a8c-7f310f550bde.html |
(NewsNation) — While questions remain about a mystery company buying 52,000 acres of land near an Air Force base, a congressman says farmers in the area are being targeted in a lawsuit.
Rep. John Garamendi, D-Calif., has been speaking out over the past five years about the $800 million in land acquisitions by Flannery Associates near Travis Air Force Base in Northern California.
In an interview with NewsNation, Garamendi said he’s been in contact with the families of farmers who handed over their land to Flannery. He said they didn’t want to sell in the first place.
Since no California laws require them to sell, the land was bargained for by both parties at a much higher price. But now, Flannery is suing those families for $510 million, accusing them of conspiring together to inflate the value of the land.
“It’s a suit designed to force the farmers to lawyer up, spend tens of thousands of dollars on lawyering and maybe at the end of the day, bankrupt themselves,” Garamendi said. “In fact, that has happened to at least one family that I know of and I’ve heard rumors that another family simply said we can’t afford the lawyers.”
NewsNation reviewed a copy of the lawsuit. Attorneys for Flannery said they believe “this is a simple case about a group of wealthy landowners who saw an opportunity to conspire, collude, price fix and illegally overcharge Flannery.”
But Garamendi said there was no viable economic reason to justify spending several times more than what the land is worth in the first place.
The suit comes as companies with ties to China have been ramping up efforts to buy American farmland in recent years.
Public records show “Flannery Associates” has invested more than $800 million on more than 50,000 acres of land surrounding the Travis Air Force Base since 2018.
Legal representation for Flannery said the group is controlled by U.S. citizens, with 97% of its capital coming from U.S.-based investors. But after eight months of investigation, federal officials can’t confirm or deny this to be true and have not been able to determine exactly who is backing the company.
The Air Force’s Foreign Investment Risk Review office is currently investigating Flannery Associates. Garamendi said there are valid concerns that Flannery’s land acquisitions could be tied to foreign enemies.
“The fact they chose to buy all three sides of the Travis Air Force Base even raises immediate questions about national security,” Garamendi said. “So, is this Chinese money? We don’t know, but we do know that the Chinese money was being used in North Dakota and we have a very deep suspicion, given the amount of money, given the lack of attention to values, that they simply want to acquire all of this land.”
NewsNation investigated the now thwarted deal with a Chinese-owned company in Grand Forks, North Dakota. Last year, 300 acres of farmland were purchased near the Grand Forks Air Force Base in North Dakota by Chinese-owned Fufeng – a deal that raised red flags about potential spying.
After pushback from the community, the city council ultimately voted to end the project, citing national security risks.
Garamendi said local residents near Travis Air Force Base are riled up, just like the residents in Grand Forks, due to how critical the area is for the U.S. military.
“Travis Air Force Base is absolutely essential. It is the gateway to the Pacific,” Garamendi said, later adding, “A good deal of the munitions that are going to Ukraine also passed through Travis Air Force Base.”
China has been buying up American farmland for years. Nearly 384,000 acres of agricultural land in the U.S. is controlled by China, and the rate at which they are purchasing land is growing, the USDA reports.
Chinese ownership of American farmland has increased 55% in the past five years, with almost 75% of it located in the South and about 16% on the West Coast. | https://www.pahomepage.com/news/national-news/mystery-group-buying-land-near-air-force-base-is-suing-farmers-congressman-says/ | 2023-07-31T05:35:44 | 0 | https://www.pahomepage.com/news/national-news/mystery-group-buying-land-near-air-force-base-is-suing-farmers-congressman-says/ |
TUPELO, Miss. - The summer heat is a threat to some outdoor plans this summer. But, some locals won’t let the hot temperatures keep them from having fun in the sun. One group still plays soccer every Sunday at Ballard Park.
Players take precautions to stay safe in the sun. Soccer player Glendy Jax shared tips for people wanting to stay active this summer.
“I think the best thing to do first is like, practice everyday because you get used to it,” Jax said. “And, like drinking water being healthy and like taking some breaks too because then you will get tired.”
Other tips include being out in the later hours of the day, using cool sweat rags, and wearing light weight clothes. | https://www.wtva.com/news/staying-safe-while-being-active-in-the-heat/article_e7c33306-2f51-11ee-a3fe-cf64c495f66f.html | 2023-07-31T05:35:45 | 1 | https://www.wtva.com/news/staying-safe-while-being-active-in-the-heat/article_e7c33306-2f51-11ee-a3fe-cf64c495f66f.html |
Much of the Orioles’ rebuild was spent out of the national spotlight, though that’s likely where they preferred their recurrent defeats, the all-too-common games where the opposing team put them in an insurmountable hole.
On Sunday, they returned the favor to one of the frequent deliverers of those challenging nights, beating the New York Yankees, 9-3, in front of a national audience on ESPN’s “Sunday Night Baseball,” while setting a franchise record by striking out 18 opposing batters in a nine-inning game. By winning Sunday, the Orioles claimed the season series against the Yankees for the first time since 2016, the season of their most recent playoff berth. They entered this year 20-47 against New York under manager Brandon Hyde, including a 2-17 record in his first season in 2019.
“I have a little bit more competitive roster, so that makes it nice,” Hyde said. “It’s a little bit more fair fight than it has been in the past. We’re able to pitch to them — we didn’t in the past — and we’re able to score some runs, and we had a tough time in that in the past. We’re a lot more talented than my first few years here, and so it’s a little bit more fair.”
The last time Camden Yards hosted a “Sunday Night Baseball” was also against New York, with that Aug. 26, 2018, defeat one of the many in a four-year span in which the Orioles lost 36 more games than any other organization.
But Baltimore (64-41) has come out the other side as one of baseball’s best teams. They lead the Tampa Bay Rays by 1 1/2 games in the American League East, with the Yankees (55-50) in last and nine games behind Baltimore despite having a record that would put them atop the AL Central.
The Orioles’ improved play is beginning to show in the Camden Yards stands. With an announced crowd of 37,429 on Sunday, the weekend series represented Baltimore’s best draw for a three-game set since July 2016.
“When it’s packed out and you hear the crowd getting into it, there’s no better feeling,” Orioles All-Star catcher Adley Rutschman said. “Everyone gets that much more excited and just feels like the atmosphere that you dream about playing in. And it’s here.”
Hyde treated the game as dicier than the score indicated it was, but the Orioles led comfortably throughout thanks to a seven-run first inning. Baltimore’s first six batters reached against Yankees right-hander Luis Severino, who they had likewise pummeled in a start earlier this month in New York.
After singles by Adley Rutschman and Gunnar Henderson, doubles from Anthony Santander and Ryan O’Hearn, and a walk from Austin Hays, Adam Frazier highlighted the frame with a three-run home run. Batting leadoff for the second straight game, Rutschman came back around for a second time and singled again, driving in Jordan Westburg for the frame’s final run. It was the third time this season the Orioles scored seven runs in an inning against the Yankees.
Rutschman, Baltimore’s first pick in the 2019 draft, added a walk and another single as he continued reaching base while moving one spot up the order. The 25-year-old figured these past two games were his first time batting leadoff since he was a sophomore in high school.
“I kind of just show up and do what they tell me,” Rutschman said. “I feel like there’s a mental stigma behind batting in different positions, but I’m just trying to do the same exact thing, just in the leadoff spot.”
Added Hyde: “When I talked to him about it, I said, ‘Don’t change. Just because you’re leading off the game, your at-bats are exactly the same. You’re just hitting above Gunnar instead of hitting after him.’”
Baltimore starter Dean Kremer struck out two in a perfect top of the first, but struggled to work efficiently once provided the large lead. He left the bases loaded in the second and surrendered two deep flyballs to open the third, the first from Jake Bauers landing in the Orioles’ bullpen for a home run and the second hitting the top of Camden Yards’ deep left field wall for a double by Gleyber Torres. Kremer recovered to strike out New York’s next three batters, but Bauers’ double off Kremer in the fourth plated another run.
The Orioles answered with RBI doubles by Henderson and O’Hearn, chasing Severino and leaving him with 16 earned runs allowed and 18 outs recorded across two starts against them this month. But Kremer did not outlast him by much. On his 90th pitch, Giancarlo Stanton singled to center, eventually coming home with Mike Baumann on the mound to leave Kremer with three runs surrendered over four-plus innings. Hyde was unsure whether the long first inning factored into Kremer’s performance, but the right-hander didn’t bemoan it.
“You can’t complain when the team puts up a touchdown and the extra point,” Kremer said. “Our team, when they get going, they’re pretty fun to watch.”
Baltimore’s bullpen was otherwise spotless over its five innings of work. After an early defensive substitution from Hyde — taking out second baseman Jordan Westburg as part of a series of moves to get Ryan McKenna in center and Frazier out of left field — Shintaro Fujinami, the Orioles’ lone trade acquisition thus far ahead of Tuesday’s deadline, worked two scoreless innings, giving him 4 2/3 scoreless frames and seven strikeouts in his past three outings, and Danny Coulombe followed with a shutout eighth.
Although the Orioles led by six runs throughout, All-Star setup man Yennier Cano warmed up in the bullpen three times, then entered for the ninth, with Hyde acknowledging he would have preferred to avoid using him in that situation but that Kremer’s short start left him with limited options. Cano struck out the side for 18 total strikeouts by Baltimore pitching, the team’s most for a nine-inning game and tied for its third most for a game of any length.
“I love the way our guys play,” Rutschman said. “I think we’re really talented, and we play together. I’m excited to see what we can do.” | https://www.capitalgazette.com/sports/bs-sp-orioles-yankees-sunday-night-baseball-20230731-ayetyvojjzhbdffghebxqvx474-story.html | 2023-07-31T05:36:05 | 0 | https://www.capitalgazette.com/sports/bs-sp-orioles-yankees-sunday-night-baseball-20230731-ayetyvojjzhbdffghebxqvx474-story.html |
RICHMOND, Va. — Chris Buescher was already in good position to qualify for NASCAR’s playoffs.
Now, even something remarkable over the last four races of the regular season won’t keep him out.
Buescher pulled away on a restart with three laps to go to win at Richmond Raceway on Sunday and snag one of the final spots in NASCAR’s playoff field.
Buescher led 88 laps and was ahead by nearly 6 seconds when a caution came out with under 10 laps to go. That erased his lead over Virginia native Denny Hamlin, who was booed by his hometown crowd before the race.
But Hamlin got a poor final restart and Buescher easily pulled away for his first Cup Series win of the season, third of his career.
“I knew that last restart was going to be tough, but I knew we had the speed in this thing,” Buescher said.
He and RFK Racing teammate Brad Keselowski led a combined 190 of the 400 laps in their Fords. Keselowski, now a part owner of the team, led 102 laps on the 0.75-mile oval.
Buescher started 26th and had to drive through the field for the win that locked him into the 16-driver playoff field. Buescher became the 13th race winner this year and there are three playoff spots up for grabs over the next month.
It was the 139th Cup win for primary team owner Jack Roush, second since Keselowski joined the ownership group.
Ford now has 723 wins in NASCAR’s top Cup Series.
“Everybody at RFK Racing who has worked so hard to get us to this point,” said Buescher.
Hamlin, winner last week at Pocono, finished second in a Toyota for Joe Gibbs Racing. Kyle Busch was third in a Chevrolet for Richard Childress Racing, followed by the Fords of Joey Logano from Team Penske and Ryan Preece of Stewart-Haas Racing.
“One win is good, but you get three or four or five and then you feel a lot better,” Keselowski said. “It sure beats not having any at all, but we want to keep going. It’s nice to have one car locked in the playoffs. We need to get both cars locked in the playoffs. We have a good points gap, but we want wins and this is where we need to be.”
Keselowski, despite being winless this season, is still mathematically in contention for the playoffs.
The race was slowed just three times by caution flags, with the final yellow sending the leaders to pit road for four tires with eight laps to go. When the green flag was shown again, Buescher used the inside line to pull away for his third career victory.
Hamlin’s bid for the victory ended on the second lap of the final sprint when he drove in too deep in the first turn and slid up the track. He finished 0.549-seconds behind Buescher.
“I got a bad restart,” Hamlin said. “I had to recover too much ground from what I lost on the front stretch. Almost got to the outside, and then in turn four, almost got to the outside again, and then in turn one, I was like ‘I’m just going to ship it in there and try to get to the outside one more time’ and I just carried way too much speed and locked up the left front tires.”
Larson-Hamlin
Kyle Larson, angered last week when Hamlin caused him to hit the wall while leading while Hamlin went on to win, was running a few laps down when he nudged Hamlin out of the way with 70 laps to go during Sunday’s race.
Larson, who won at Richmond in April, finished 19th.
“I think he was having a frustrating day,” Hamlin said. “It’s all good.”
Scorcher
With temperatures in the mid-80s, it was about 15 degrees cooler than Saturday, when the temperature approached 100 and the heat index was at least 105.
Nevertheless, points leader Martin Truex Jr. still struggled.
“It was definitely really, really hot,” he said. “It felt longer than 400 laps. I’ll be honest, when we got to the end of stage two —– I thought there was no way. I thought that was the checkered flag. It just felt really, really long.”
Truex finished seventh.
Clean race
All 36 cars that started the race were still running at the end.
Up next
The series moves to Michigan where Kevin Harvick, winless so far in this his final season, is the defending champion. | https://www.capitalgazette.com/sports/ct-ap-nascar-richmond-20230731-76sa5ydnr5h77dcd2luloaesfu-story.html | 2023-07-31T05:36:06 | 1 | https://www.capitalgazette.com/sports/ct-ap-nascar-richmond-20230731-76sa5ydnr5h77dcd2luloaesfu-story.html |
HONG KONG, July 31, 2023 /PRNewswire/ -- Akeso Inc. ("Akeso", the "Company"; 9926.HK), a commercial-stage biopharmaceutical company focused on developing and commercializing first-in-class and best-in-class innovative medicines globally, today announced that it is expected that the Company will record a profit of not less than RMB2.3 billion for the six months ended June 30, 2023. This is the first time for the Company to achieve half-year profits.
The turnaround from loss to profit during the Reporting Period was mainly attributable to:
- In respect of Ivonescimab (AK112, PD-1/VEGF) independently developed by the Company, the Company has entered into the collaborative and licensing agreement with Summit Therapeutics (details of which are set out in the announcement of the Company dated December 6, 2022). The Company has received the total upfront payment equivalent to US$500 million in full during the first quarter of 2023 (details of which are set out in the announcements of the Company dated January 26, 2023 and March 6, 2023). Part of such upfront payment was recognized as licensing fee income which significantly contributed to the revenue of the Company for the Reporting Period, and amounted to approximately RMB2.9 billion. The revenue recognition of the remaining portion of the upfront payment will be recognized as revenue in batches going forward.
- In respect of the Company's innovative product 开坦尼® (cadonilimab, PD-1/CTLA-4), since its launch in June 2022, it has recorded significant increase of the patients as well as product sales, which reflects the excellent clinical value of cadonilimab. In addition, 安尼可®(penpulimab, PD-1) also continued to contribute to the growth in the Company's product sales revenue during the Reporting Period.
- The Company has continued to optimise its cost management capabilities in a scientific and efficient way and has achieved better results in cost control while accelerating innovative products development and pipelines advancement.
About Akeso
Akeso (HKEX: 09926) is a commercial-stage biopharmaceutical company committed to the discovery, development, manufacturing, and commercialization of innovative medicines with high unmet medical needs worldwide. Founded in 2012, the Company has established a comprehensive in-house drug development platform (ACE Platform) and know-how, including R&D, clinical development, CMC (Chemistry, Manufacturing, and Controls), and commercialization capabilities.
With fully integrated multi-functional platform, Akeso is internally working on a robust pipeline of over 30 innovative assets in the fields of cancer, autoimmune disease, inflammation, metabolic disease, and other major therapeutic areas. 19 assets have entered clinical stage. Leveraging in-house developed bispecific platform technology ("Tetrabody technology"), the Company has advanced four potential first-in-class bispecific antibody drugs into market or clinical development, including cadonilimab (PD-1/CTLA-4), ivonescimab (PD-1/VEGF), PD-1/LAG-3, TIGIT/TGF-Beta bispecific antibodies. In June 2022, cadonilimab was approved by the NMPA and became the first commercialized PD-1 based bispecific drug globally. Another Akeso internally discovered and developed oncology product, penpulimab (a PD-1 antibody), was granted marketing approval in China in August 2021. In December 2022, the Company out-licensed breakthrough bispecific antibody, ivonescimab (PD-1/VEGF bi-specific antibody, AK112), with up to US$5 Billion total potential deal value to Summit Therapeutics for development and commercialization in the U.S., Canada, Europe, and Japan.
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SOURCE Akeso, Inc. | https://www.wistv.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ | 2023-07-31T05:37:38 | 0 | https://www.wistv.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ |
Brittney Griner will not travel with the Phoenix Mercury for their next two games to focus on her mental health, the organization said Saturday.
The All-Star center returned to the WNBA this year after her release from a Russian prison. She was arrested and jailed over a drug charge in Russia that resulted in the U.S. conducting a prisoner swap for her. Convicted arms dealer Viktor Bout was sent back to Russia as part of the deal.
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In her return, Griner has averaged 18.2 points and 6.7 rebounds in 20 games. She missed the entire 2022 season while she was imprisoned overseas.
"The Mercury fully support Brittney and we will continue to work together on a timeline for her return," the Mercury said.
WNBA CHAMP RIQUNA WILLIAMS ARRESTED AFTER ALLEGED DOMESTIC INCIDENT INVOLVING WIFE, EXPLOSIVE DETAILS EMERGE
Griner's success on the court hasn’t translated into much winning. Phoenix is 6-17 on the year and fired coach Vanessa Nygaard earlier in the season.
Griner and her Mercury teammates were also confronted at the Dallas airport by a so-called "provocateur." Additionally, the center has been dealing with a hip issue.
Phoenix is on the road against the Chicago Sky and the Indiana Fever.
Without Griner on Sunday, the Mercury fell to the Sky, 104-85.
The Associated Press contributed to this report. | https://www.foxbangor.com/sports/national-sports/brittney-griner-away-from-road-tripping-mercury-due-to-mental-health-reasons/article_4d40f91c-2b31-56a5-a75e-034324cd1e3f.html | 2023-07-31T05:37:40 | 1 | https://www.foxbangor.com/sports/national-sports/brittney-griner-away-from-road-tripping-mercury-due-to-mental-health-reasons/article_4d40f91c-2b31-56a5-a75e-034324cd1e3f.html |
SEOUL, South Korea, July 31, 2023 /PRNewswire/ -- J INTS BIO announced the successful dosing of the first patient in its global multi-center Phase 1/2 clinical study of 'JIN-A02' on 31st July at Severance Hospital, Seoul, Korea.
More clinical sites will follow suit, including seven more hospitals in Korea (National Cancer Center, Chungbuk National University Hospital, Samsung Seoul Hospital, Seoul National University Hospital, Seoul St. Mary's Hospital, St. Vincent Hospital, Asan Medical Center), two in the United States, and one in Thailand.
This global phase 1/2 clinical trial seeks to evaluate the safety, pharmacokinetics and anti-tumor activity of "JIN-A02" in advanced NSCLC patients carrying EGFR mutations.
'JIN-A02' is a novel orally administered 4th Generation EGFR TKI, which is highly selective for and strongly inhibits NSCLC with C797S double or triple mutations, showing efficacy even against intracranial tumors by exhibiting high blood-brain barrier penetrance.
Anna Jo, CEO of J INTS BIO, said, "We expect the positive results of 'JIN-A02' in the pre-clinical studies to translate to positive outcomes for patients in the clinical trial" adding that, "We hope also to proceed with the application for designation of orphan drug, and thereby quickly occupy the global NSCLC therapy market through conditional use."
About J INTS BIO
J INTS BIO is a bio company specialized in developing innovative anti-cancer and orphan drugs to realize the goal of changing lives and improving health for patients around the world. J INTS BIO's teams have prior multi-year experience in multinational pharmaceutical companies and CROs and track records in medical, regulatory affairs, drug discovery and development.
About 'JIN-A02'
'JIN-A02' is a novel orally administered 4th Generation EGFR TKI targeting C797S mutations in NSCLC. Although 1st, 2nd, and 3rd Generation EGFR TKIs have been used with some success, recurrence occurs in most patients including those on 3rd Generation TKIs such as Osimertinib. Currently, there are no approved therapies for patients who developed EGFR C797S mutations due to the use of 3rd Generation EGFR TKIs and with the high propensity of these cancers to metastasize to the brain, there is an urgent need to develop an effective drug with high blood-brain barrier permeability as well. 'JIN-A02', a novel oral EGFR TKI, which is effective against C797S double and triple mutations and have a high brain penetrance, is therefore expected to become the most promising Best-in-Class 4th-generation EGFR TKI in NSCLC patients with limited or no viable treatment options.
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SOURCE J INTS BIO | https://www.wistv.com/prnewswire/2023/07/31/j-ints-bio-novel-oral-4th-generation-egfr-tki-jin-a02-dosing-first-patient-global-multi-center-phase-12-clinical-study-began/ | 2023-07-31T05:37:44 | 0 | https://www.wistv.com/prnewswire/2023/07/31/j-ints-bio-novel-oral-4th-generation-egfr-tki-jin-a02-dosing-first-patient-global-multi-center-phase-12-clinical-study-began/ |
Pat McAfee, ESPN’s newest broadcaster, came under fire Sunday after he referenced disgraced sports doctor Larry Nassar in a joke about Michigan State football’s uniforms.
McAfee was responding to one of his producers commenting on the Spartans’ very green uniforms with "STATE" emblazoned across the chest. The former Indianapolis Colts punter, who has built a major brand hosting his own radio show, reacted with an apparent joke in reference to Nassar.
"I think Nassar was in on the design team actually," McAfee tweeted.
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When one person responded with a GIF that contained a screencap that read, "I think you’d better delete that one," McAfee responded with a GIF of his own.
"For what? For what?" McAfee’s GIF read.
Still, McAfee came under fire on social media.
ESPN declined to comment. The company announced in May that McAfee was moving his show to the company.
ESPN gave the Arthur Ashe Courage Award to the survivors of Nassar's assaults.
Nassar is serving decades in prison for sexually assaulting gymnasts, including Olympic medalists. He admitted sexually assaulting athletes when he worked at Michigan State University and USA Gymnastics.
He also pleaded guilty to possessing child pornography.
During victim impact statements in 2019, several athletes testified that over the course of Nassar’s more than two decades of sexual abuse, they had told coaches and trainers and other adults what was occurring, but it went unreported.
AARON RODGERS TORCHES SEAN PAYTON OVER NATHANIEL HACKETT REMARKS, GIVES STERN WARNING
Nassar is likely to spend the rest of his life behind bars.
More than 150 victims spoke or submitted statements during the seven-day hearing, including Simone Biles. The women sought more than $1 billion from the federal government over the FBI’s failure to stop Nassar when agents became aware of the allegations against him in 2015.
A final appeal from Nassar was rejected by the Michigan Supreme Court last month. Attorneys for Nassar said he was treated unfairly in 2018 and deserved a new hearing based on the judge calling him a "monster," among other remarks.
"I just signed your death warrant," Ingham County Judge Rosemarie Aquilina said of Nassar’s 40-year sentence.
While the Michigan Supreme Court said it had concerns over the judge’s conduct, officials noted Aquilina stuck to the sentencing agreement worked out by the lawyers on the case.
"We decline to expend additional judicial resources and further subject the victims in this case to additional trauma where the questions at hand present nothing more than an academic exercise," the court said.
The Associated Press contributed to this report. | https://www.foxbangor.com/sports/national-sports/pat-mcafees-larry-nassar-joke-about-michigan-state-football-leads-to-backlash/article_4d529c1b-95b7-52b4-98c7-cb804e49aeca.html | 2023-07-31T05:37:46 | 1 | https://www.foxbangor.com/sports/national-sports/pat-mcafees-larry-nassar-joke-about-michigan-state-football-leads-to-backlash/article_4d529c1b-95b7-52b4-98c7-cb804e49aeca.html |
DHAKA, Bangladesh, July 31, 2023 /PRNewswire/ -- Nagad, a popular mobile money carrier based in Bangladesh, has emerged as a unicorn startup only in four years of its journey – the fastest in Bangladesh to reach this remarkable feat.
In recognition of the achievement, Tanvir A Mishuk, founder and managing director of Nagad Ltd., received the "Fastest to Unicorn Award" from Honourable Prime Minister of People's Republic of Bangladesh Sheikh Hasina at the inaugural ceremony of the two-day "Bangladesh Startup Summit 2023" in Hotel InterContinental Dhaka on 29 July 2023, hosted by Startup Bangladesh Ltd., the flagship venture capital company of the Government of Bangladesh's ICT Division.
Nagad has reshaped the country's MFS industry with one after another disruptive innovation and inspired confidence among people to embrace its products and services that are convenient and affordable. In this way, the state-owned mobile money carrier has established itself as the fastest unicorn startup in Bangladesh.
Presenting a keynote at the startup summit, State Minister for Information and Communication Technology Zunaid Ahmed Palak lauded Nagad's contribution to building a smart economy in Bangladesh.
Founder and Managing Director of Nagad Ltd. Tanvir A Mishuk said, "The way Digital Bangladesh is marching ahead we should have achieved the unicorn status much earlier. Now, our challenge is to take our company's valuation to USD 2 billion."
Increasing the valuation is not Nagad's main target, rather, it has embarked on its journey mainly to bring unbanked people under financial inclusion and get them used to digital payments, he also, adding, "We have already come a long way in meeting our target."
The way payments continue to evolve in keeping with people's changing lifestyle, there is no denying the fact that cashless is the future. Bangladesh government has taken many initiatives to attract people to digital payments. To complement the country's digital vision, Nagad is also working relentlessly to introduce new products and services required to accelerate the country's transition to a cashless society.
To grow into a complete financial solution, the MFS provider is going to establish a digital bank that will make available all financial services on a single platform. The mobile money carrier has already prepared itself accordingly.
"If we get the licence for digital bank, we will introduce collateral-free loans for small informal businesses who now take loans from moneylenders at 40% interest rate per day," said the Nagad MD.
If everything continues to go in the right direction, Bangladesh will emerge as a Smart Nation by 2041, envisioned by PM Sheikh Hasina.
About Nagad Ltd (https://www.nagad.com.bd/)
Nagad Limited is one of the leading MFS operators in Bangladesh's payment industry with 80 million registered customers and an average daily transaction of about USD 112 million. The digital payment platform, known as a successful public-private partnership between Bangladesh Postal Department and the private sector, was inaugurated in 2019 by Prime Minister Sheikh Hasina of the People's Republic of Bangladesh.
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SOURCE Nagad Limited | https://www.wistv.com/prnewswire/2023/07/31/nagad-becomes-bangladeshs-fastest-unicorn/ | 2023-07-31T05:37:50 | 1 | https://www.wistv.com/prnewswire/2023/07/31/nagad-becomes-bangladeshs-fastest-unicorn/ |
NANJING, China, July 31, 2023 /PRNewswire/ -- Nanjing Leads Biolabs Co., Ltd. (hereinafter referred to as "Leads Biolabs" or "Company") announced today that the National Medical Products Administration (NMPA) and the U.S. Food and Drug Administration (FDA) have approved its first-in-human Investigational New Drug (IND) applications for LBL-034, an anti-GPRC5D/CD3 bispecific antibody invented by Leads Biolabs with global intellectual property rights, for the treatment of relapsed/refractory multiple myeloma. Currently, no GPRC5D-targeting antibody has been approved for marketing.
This is a first-in-human, single-arm, multicenter, open-label, dose-escalation and expansion clinical study, and plans to enroll patients with relapsed/refractory multiple myeloma who have failed prior therapies including but not limited to at least one proteasome inhibitor (PI), one immunomodulator (IMiD) as well as other standard treatments. This study aims to evaluate the safety and tolerability of LBL-034, determine the recommended Phase II dose and assess its efficacy in patients with multiple myeloma.
"Despite recent progress and continuous advancements in multiple myeloma, the time between recurrences has been steadily decreasing, particularly as the number of treatment lines increases. This ultimately leads to emergence of relapsed or refractory multiple myeloma, reaffirming its status as an incurable malignant tumor that poses a serious threat to human life. In light of this challenging reality, the urgent need for more effective and innovative treatment options has never been more evident." said Dr. Charles Cai, Chief Medical Officer of Leads Biolabs, "LBL-034 adopts a unique molecular design, which enables the drug to specifically bind to GPRC5D-expressing tumor cells with high affinity, and reduces the risk of non-specific activation of T-cells, thereby enhancing anti-tumor efficacy and reducing potential risk of immunotoxicity. LBL-034 demonstrated robust anti-tumor activities and good safety profile in pre-clinical studies. We adhere to our tradition of innovation and aim to deliver an important, novel and effective treatment option for patients with poor prognosis of relapsed/refractory multiple myeloma."
About GPRC5D:
G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D) is a C-type 7-channel transmembrane receptor protein. GPRC5D is low expressed in normal human tissues but specifically overexpressed in multiple myeloma. The intensity of GPRC5D expression is an independent prognostic factor in multiple myeloma, and its overexpression is significantly associated with reduced overall survival. Therefore, GPRC5D may be an important potential target for the treatment of plasma cell diseases such as multiple myeloma.
About multiple myeloma:
Multiple myeloma is a malignant plasma cell disease caused by abnormal proliferation of clonal plasma cells, accounting for 10-15% of hematologic malignancies and about 1.4% of all malignancies. It is the second most common hematological malignancy in adults after non-Hodgkin's lymphoma and mostly occurs in the elderly. According to the data released by the World Health Organization (WHO), the number of new cases and deaths of multiple myeloma worldwide in 2020 were 176,000 and 117,000 respectively, and the number of new cases and deaths of multiple myeloma in China were 21,000 and 16,000 respectively. Currently, multiple myeloma is still an incurable malignant tumor, and the five-year survival rate of patients is approximately 24.8% in China, 33.3% in Japan, and 46.7% in the United States. In recent years, with the successful development of proteasome inhibitors (PIs), immunomodulatory drugs (IMiDs), selective nuclear output inhibitors, CD38-targeted antibodies, bispecific antibodies, and CAR-T cell therapies, the tumor response rate and survival prognosis have been significantly improved. However, multiple myeloma remains an unmet clinical need for more effective treatments.
About LBL-034:
LBL-034 is a humanized IgG1 subtype asymmetric bispecific antibody targeting both GPRC5D and CD3 and Leads Biolabs fully owns the worldwide intellectual property rights. LBL-034 induces T-cell-mediated killing of myeloma cells by redirecting CD3+ T-cells to myeloma cells expressing GPRC5D.
LBL-034 has the potential to be a transformative best-in-class GPRC5D-targeted immunotherapy for multiple myeloma. Clinical studies are planned to evaluate the safety and efficacy of LBL-034 in patients with relapsed/refractory multiple myeloma.
Nanjing Leads Biolabs Co., Ltd. is a clinical-stage biotechnology company founded in Nanjing by a team of senior U.S.-trained antibody drug developers. Since 2014, Leads Biolabs has been dedicated to the discovery and development of novel antibody drugs with independent intellectual property rights for the treatment of oncology and other major diseases of high unmet medical needs, particularly the challenges in cancer immunotherapy. Our extensive R&D pipeline consist of more than twenty novel tumor immunotherapy molecules based on monoclonal and bispecific antibody technology platforms. Leads Biolabs is committed to providing safe, effective, accessible and affordable new drugs to address the unmet needs of patients around the world.
For more information, please visit: https://www.leadsbiolabs.com
Business contact: bd@leadsbiolabs.com
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SOURCE LEADS BIOLABS | https://www.wistv.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ | 2023-07-31T05:37:57 | 1 | https://www.wistv.com/prnewswire/2023/07/31/nmpa-fda-approved-first-in-human-clinical-trial-applications-evaluate-lbl-034-an-anti-gprc5dcd3-bispecific-antibody-developed-by-leads-biolabs-relapsedrefractory-multiple-myeloma/ |
More experienced principals leave the profession at higher rates
WASHINGTON, July 31, 2023 /PRNewswire/ -- Roughly 1 in 10 (11 percent) public school principals left the profession between the 2020-21 and 2021-22 school years, according to data from the National Teacher and Principal Survey (NTPS) released today by the National Center for Education Statistics (NCES), the statistical center within the U.S. Department of Education's Institute of Education Sciences (IES).
"Principal attrition is higher in public schools than it was 5 years ago, and veteran public school leaders with more years of experience leave the profession at higher rates than those with less experience," said NCES Commissioner Peggy G. Carr. "Principals are critical supports for a school's teachers and learners, and the country needs leaders in every school who are committed to the success of each student. These data are a valuable snapshot for those at the district and state levels who must address the issue of principal turnover in their schools."
Approximately 80 percent of 2020-21 public school principals remained at the same school one year later ("stayers"), which was lower than the percentage of 2016-17 public school principals who were still at their school 1 year later (82 percent). Six percent of 2020-21 public school principals moved to a different school ("movers"), and 11 percent left the principalship ("leavers"). For private school principals in 2020-21, approximately 83 percent remained at the same school during the following school year, 2 percent moved to a different school, and 10 percent left the principalship.
Additionally, among 2020-21 public school principals who somewhat or strongly agreed they would leave the principalship as soon as possible if they could get a higher paying job (about 25 percent), approximately 73 percent stayed the following school year, while about 15 percent left the profession.
"These data are critical to understanding patterns of principal attrition," said NCES Associate Commissioner Chris Chapman. "We are able to observe how principal attrition has changed over the years, as well as how principal attrition and mobility vary based on characteristics of the principals and their schools."
The report released today includes selected findings from the Principal Follow-up Survey (PFS), a longitudinal component of the National Teacher and Principal Survey (NTPS), which is a nationally representative survey of public and private K-12 schools, principals, and teachers in the 50 states and the District of Columbia. Data were collected from January 2022 through June 2022. The sample included about 6,500 public school principals and about 1,800 private school principals, for a total sample size of about 8,300 principals.
The data were collected as a follow-up to the 2020-21 NTPS to provide attrition and mobility information about principals in K-12 public and private schools. The purpose was to ascertain how many principals from the 2020-21 school year still worked as a principal in the same school 1 year later ("stayer"), how many had moved to become a principal in another school ("mover"), and how many were no longer working as a principal ("leaver").
Key Findings
- Of all public school principals in 2020-21, 11 percent left the profession by the 2021-22 school year. This was higher than in 2016-17, when 10 percent of all public school principals had left the profession since 2015-16, but not measurably different from the 2012-13 school year, when 12 percent of all public school principals had left the profession since the previous school year, or from 2008-09, when 12 percent of all public schools had left the profession since the previous school year.
- Of all public school principals in 2020-21 with more than 10 years of experience as a principal at any school, 15 percent left the profession by the 2021-22 school year. Of those principals with 10 years or more experience as a principal in their current school, 16 percent left the profession.
- A higher percentage of school principals 55 years of age or older left the profession compared to principals between 45-54 years of age.
- Among the 9 percent of 2020-21 public school principals with a salary of less than $75,000, 76 percent remained at the same school during the 2021–22 school year, 7 percent moved to a different school, and 13 percent left the principalship.
- Among the 33 percent of 2020-21 public school principals with a salary of $115,000 or more, 81 percent remained at the same school during the 2021-22 school year, 6 percent moved to a different school, and 10 percent left the principalship.
- Among the 62 percent of 2020-21 private school principals with a salary of less than $75,000, 81 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 10 percent left the principalship.
- Among the 13 percent of 2020-21 private school principals with a salary of $115,000 or more, 85 percent remained at the same school during the 2021-22 school year, 3 percent moved to a different school, and 8 percent left the principalship.
The National Center for Education Statistics, a principal agency of the U.S. Federal Statistical System, is the statistical center of the U.S. Department of Education and the primary federal entity for collecting and analyzing data related to education in the U.S. and other nations. NCES fulfills a congressional mandate to collect, collate, analyze, and report complete statistics on the condition and progress of American education; conduct and publish reports; and review and report on education activities internationally.
Follow NCES on Twitter, Facebook, LinkedIn, and YouTube and subscribe to the NCES Newsflash to receive email notifications when new data is released.
The Institute of Education Sciences (IES) is the independent and nonpartisan statistics, research, and evaluation arm of the U.S. Department of Education. Its mission is to provide scientific evidence on which to ground education practice and policy and to share this information in formats that are useful and accessible to educators, parents, policymakers, researchers, and the public.
CONTACT: Josh Delarosa, National Center for Education Statistics, ARIS.NCES@ed.gov
James Elias, Hager Sharp, jelias@hagersharp.com
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SOURCE National Center for Education Statistics | https://www.wistv.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ | 2023-07-31T05:38:03 | 0 | https://www.wistv.com/prnewswire/2023/07/31/roughly-one-ten-public-school-principals-left-profession-2021-22-school-year/ |
HANOI, Vietnam, July 31, 2023 /PRNewswire/ -- SeABank's stock (SSB) has been officially selected by the Ho Chi Minh City Stock Exchange (HOSE) to be included in the VN30-Index basket - an index representing the top 30 stocks with the highest market capitalization and liquidity listed on the HOSE.
At the end of the trading session on July 28, 2023, the closing price of SSB's stock was 29,700 VND per share, bringing SeABank's market capitalization to over 72,875 billion VND, equivalent to nearly 3.07 billion USD.
According to the press release, on July 17, 2023, HOSE announced the portfolio of stocks included in the VN30 and VN-Finlead indexes, which would be effective from August 7, 2023. SSB was chosen to be included in the VN30 basket as it met the requirements set by the HOSE Index Rules. With an average market capitalization of nearly 65,000 billion Vietnamese dongs over the past six months, SSB is one of the largest capitalized stocks among those not included in the previous VN30 basket.
Throughout its operations, SeABank prioritizes transparency by providing information to shareholders, partners, and customers, complying with legal regulations, and following the directives of the Government and the State Bank of Vietnam to stabilize the market, ensure smooth operations, and promote business activities, thereby contributing to the country's socio-economic development.
SeABank's stock (SSB) was officially listed on the HOSE on March 24, 2021, with a reference price of 16,800 Vietnamese dongs per share on its first trading day. It has consistently experienced stable growth since then. In June 2023, SeABank successfully issued shares for dividend payment and additional capital from shareholder funds (bonus shares) with a total ratio of 20.3% to increase its charter capital to 24,537 billion Vietnamese dong.
Previously, SSB was also added to the Morgan Stanley Capital Index (MSCI) Frontier Markets Index starting from March 1, 2023. According to experts, stocks included in the MSCI Frontier Markets Index may be targeted by ETF (Exchange Traded Fund) funds that track frontier market stocks. Some funds use this index as a reference for investment or replicate its portfolio.
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SOURCE SeABank | https://www.wistv.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ | 2023-07-31T05:38:10 | 1 | https://www.wistv.com/prnewswire/2023/07/31/seabanks-stock-ssb-has-been-selected-by-hose-be-included-vn30-index-basket/ |
BISMARCK, N.D. — On day three of the Class A state tournament, Wahpeton stays undefeated after a win over Kindred, while the Dickinson Volunteers and Bismarck Senators seasons come to an end.
Baseball: Wahpeton stays undefeated in Class A state tournament
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Subscribe Now | https://www.kxnet.com/sports/local-sports/baseball-wahpeton-stays-undefeated-in-class-a-state-tournament/ | 2023-07-31T05:38:57 | 0 | https://www.kxnet.com/sports/local-sports/baseball-wahpeton-stays-undefeated-in-class-a-state-tournament/ |
BISMARCK, N.D. — This week’s state tournament action brought out the best in the athletes. With that being said, let’s take a look at this week’s top plays.
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Subscribe Now | https://www.kxnet.com/sports/local-sports/top-plays-july-30/ | 2023-07-31T05:39:03 | 0 | https://www.kxnet.com/sports/local-sports/top-plays-july-30/ |
We’ve seen quite a bit of rainfall in the past 48 hours. Learn more about how much we saw and the start of the work week in your full forecast.
We’ve seen quite a bit of rainfall in the past 48 hours. Learn more about how much we saw and the start of the work week in your full forecast. | https://www.kxnet.com/weather/carolyns-full-forecast-at-10pm-7-30/ | 2023-07-31T05:39:09 | 1 | https://www.kxnet.com/weather/carolyns-full-forecast-at-10pm-7-30/ |
Luzerne County’s allotment of American Rescue Plan money is almost depleted, after county council approved $6 million in Rescue Plan funding for improvement projects at Wyoming Valley Airport last week.
The county received
$112.9 million in federal Rescue Plan economic stimulus funding.
Over the past year, council allotted those funds to organizations, nonprofits, businesses and governmental entities that applied for a share of the funding to complete projects that meet guidelines established by the U.S. Treasury Department.
Council also approved funding requests for several internal projects from county departments and divisions.
Prior to council’s vote to approve the Wyoming Valley Airport projects on July 25, county Manager Romilda Crocamo told council members about $7.4 million in Rescue Plan funds remained.
After the $6 million allotment for the county-owned airport in Forty Fort, that number sits at about $1.4 million.
Councilman Tim McGinley said he was concerned that is a thin cushion in case council wants to approve Rescue Plan funding for other uses.
Last week, he proposed an amendment to cut the airport’s funding in half, to
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$3 million. However, no other council member supported the amendment.
Councilmen Brian Thornton and Kevin Lescavage said the airport has been neglected for years, and needs the funding for upgrades that will improve public safety.
Crocamo said the county has accrued interest on the Rescue Plan funds since around the start of the year. That will boost the amount available for council to allot, she said, though no hard figures were provided.
On Sunday, McGinley said he is worried about what will happen if projected costs increase for projects that council approved for Rescue Plan funding. Inflation is still high, McGinley said.
If that were to happen, very little Rescue Plan funding remains for council to allot, assuming additional funding would meet federal guidelines, he said.
Crocamo reiterated that council could use interest revenue in addition to the Rescue Plan funds that remain. Also, applications for projects were thoroughly vetted by the county’s Rescue Plan consultant as well as by council members, so major cost increases are not likely, she said.
“I don’t foresee any overages to a great extent,” Crocamo said.
A list of projects scheduled to be completed at the airport by 2026 is included with the agenda packet for the July 25 council meeting at https://is.gd/POEuGV. | https://www.citizensvoice.com/news/luzerne-countys-rescue-plan-funds-nearly-depleted-after-council-approves-airport-projects/article_97b5ebab-2998-53b4-89fe-94a30a67769c.html | 2023-07-31T05:39:27 | 0 | https://www.citizensvoice.com/news/luzerne-countys-rescue-plan-funds-nearly-depleted-after-council-approves-airport-projects/article_97b5ebab-2998-53b4-89fe-94a30a67769c.html |
Erratic winds challenge firefighters battling two major California blazes
MOJAVE NATIONAL PRESERVE, Calif. (AP) — A massive wildfire burning out of control in California’s Mojave National Preserve was spreading rapidly amid erratic winds, while firefighters reported progress against another major blaze to the southwest that prompted evacuations.
The York Fire that erupted Friday near the remote Caruthers Canyon area of the vast wildland preserve crossed the state line into Nevada on Sunday and sent smoke further east into the Las Vegas Valley.
Wind-driven flames 20 feet (6 meters) high in some spots charred more than 110 square miles (284 square kilometers) of desert scrub, juniper and Joshua tree woodland, according to an incident update. There was zero containment.
“The dry fuel acts as a ready ignition source, and when paired with those weather conditions it resulted in long-distance fire run and high flames, leading to extreme fire behavior,” the update said. No structures were threatened.
To the southwest, the Bonny Fire was holding steady at about 3.4 square miles (8.8 square kilometers) in rugged hills of Riverside County. More than 1,300 people were ordered to evacuate their homes Saturday near the community of Aguanga that is home to horse ranches and wineries.
Gusty winds and the chance of thunderstorms into Monday will heighten the risk of renewed growth, the California Department of Forestry and Fire Protection said in a statement.
One firefighter was injured in the blaze, which was 5% contained.
Copyright 2023 The Associated Press. All rights reserved. | https://www.newschannel6now.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ | 2023-07-31T05:39:27 | 0 | https://www.newschannel6now.com/2023/07/31/erratic-winds-challenge-firefighters-battling-two-major-california-blazes/ |
Eligible Supplemental Nutrition Assistance Program recipients whose benefits were electronically stolen on or after Oct. 1, 2022 in Pennsylvania can now have the benefits replaced through federal funds, the state Department of Human Services announced.
“SNAP is the nation’s most important food security program, helping more than 1.9 million Pennsylvanians put food on their tables to help them stay safe, healthy and fed. But too often, bad actors attempt to take advantage of SNAP recipients by engaging in scams and theft of these benefits,” Department of Human Services Secretary Dr. Val Arkoosh said. “I am incredibly pleased that we can now restore these benefits to the people who need them most. I encourage anyone who may qualify to reach out to DHS right away so you can restore the benefits you’re entitled to.”
SNAP benefits are eligible for replacement if they were stolen due to electronic fraudulent activity such as skimming, card cloning, phishing scams or scamming.
The Department of Human Services announced it cannot replace benefits if the client gave their physical EBT card and PIN to someone who then stole the benefits or if a physical EBT card was lost or stolen.
The maximum amount a household can receive in a single reimbursement is up to two months’ worth of their regular SNAP payments or the amount that was stolen, whichever is less, according to the Department of Human Services.
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Benefits lost to electronic fraud cannot be replaced more than two times in a federal fiscal year, which runs from Oct. 1 to Sept. 30.
SNAP recipients whose benefits were electronically stolen can go to www.dhs.pa.gov to fill out a benefit theft claim form and submit it at forms.office.com or by calling the customer service center at 1-877-395-8930.
Reports of electronic benefit theft must be reported within 60 days of the discovery of the theft.
Applications for public assistance programs, including SNAP, can be submitted at dhs.pa.gov/COMPASS. On-site CAO services are available if clients cannot access online services or need assistance that cannot be accessed through the COMPASS website, the MyCOMPASS PA mobile app or by calling the customer service center at 1-877-395-8930. | https://www.citizensvoice.com/news/stolen-snap-benefits-to-be-replaced/article_e3ae2611-2fc3-5133-8822-5e3b91be815d.html | 2023-07-31T05:39:33 | 0 | https://www.citizensvoice.com/news/stolen-snap-benefits-to-be-replaced/article_e3ae2611-2fc3-5133-8822-5e3b91be815d.html |
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BEIJING (AP) — Chinese factory activity contracted in July as export orders shrank, a survey showed Monday, adding to pressure on the ruling Communist Party to reverse an economic slowdown.
A purchasing managers’ index issued by the national statistics agency and an industry group improved to 49.3 from June’s 49 on a 100-point scale but was below the 50-point level that shows activity contracting.
“China’s manufacturing PMI remained in contraction, albeit a softer pace, as the drag from the external sector deepened,” Erin Xin of HSBC said in a report. That puts “more pressure on Beijing to support growth through both fiscal and monetary measures.”
Chinese leaders are trying to revive economic activity by promising to support entrepreneurs who generate jobs and wealth. But they have yet to give details possible tax cuts or spending and have avoided announcing a large-scale stimulus.
Demand for Chinese exports weakened after U.S. and European interest rates were raised to cool record-breaking inflation. At home, consumers are uneasy about possible job losses and are putting off big purchases. Real estate sales, an economic engine, are weak after the government tightened control on the industry’s use of debt.
An index of export orders weakened to 46.3 from June’s 46.4, well below the 50-point contraction level, according to the statistics bureau and the China Federation of Logistics & Purchasing.
Economic growth slid to 0.8% over the previous quarter in the three months ending in June from 2.2% in the January-March period. That is equal to annual growth of 3.2%, which would be among China’s weakest in decades. | https://www.seattletimes.com/business/china-factory-activity-shrinks-in-july-adding-to-pressure-to-reverse-economic-slump/?utm_source=RSS&utm_medium=Referral&utm_campaign=RSS_all | 2023-07-31T05:39:51 | 1 | https://www.seattletimes.com/business/china-factory-activity-shrinks-in-july-adding-to-pressure-to-reverse-economic-slump/?utm_source=RSS&utm_medium=Referral&utm_campaign=RSS_all |
HONG KONG, July 31, 2023 /PRNewswire/ -- Akeso Inc. ("Akeso", the "Company"; 9926.HK), a commercial-stage biopharmaceutical company focused on developing and commercializing first-in-class and best-in-class innovative medicines globally, today announced that it is expected that the Company will record a profit of not less than RMB2.3 billion for the six months ended June 30, 2023. This is the first time for the Company to achieve half-year profits.
The turnaround from loss to profit during the Reporting Period was mainly attributable to:
- In respect of Ivonescimab (AK112, PD-1/VEGF) independently developed by the Company, the Company has entered into the collaborative and licensing agreement with Summit Therapeutics (details of which are set out in the announcement of the Company dated December 6, 2022). The Company has received the total upfront payment equivalent to US$500 million in full during the first quarter of 2023 (details of which are set out in the announcements of the Company dated January 26, 2023 and March 6, 2023). Part of such upfront payment was recognized as licensing fee income which significantly contributed to the revenue of the Company for the Reporting Period, and amounted to approximately RMB2.9 billion. The revenue recognition of the remaining portion of the upfront payment will be recognized as revenue in batches going forward.
- In respect of the Company's innovative product 开坦尼® (cadonilimab, PD-1/CTLA-4), since its launch in June 2022, it has recorded significant increase of the patients as well as product sales, which reflects the excellent clinical value of cadonilimab. In addition, 安尼可®(penpulimab, PD-1) also continued to contribute to the growth in the Company's product sales revenue during the Reporting Period.
- The Company has continued to optimise its cost management capabilities in a scientific and efficient way and has achieved better results in cost control while accelerating innovative products development and pipelines advancement.
About Akeso
Akeso (HKEX: 09926) is a commercial-stage biopharmaceutical company committed to the discovery, development, manufacturing, and commercialization of innovative medicines with high unmet medical needs worldwide. Founded in 2012, the Company has established a comprehensive in-house drug development platform (ACE Platform) and know-how, including R&D, clinical development, CMC (Chemistry, Manufacturing, and Controls), and commercialization capabilities.
With fully integrated multi-functional platform, Akeso is internally working on a robust pipeline of over 30 innovative assets in the fields of cancer, autoimmune disease, inflammation, metabolic disease, and other major therapeutic areas. 19 assets have entered clinical stage. Leveraging in-house developed bispecific platform technology ("Tetrabody technology"), the Company has advanced four potential first-in-class bispecific antibody drugs into market or clinical development, including cadonilimab (PD-1/CTLA-4), ivonescimab (PD-1/VEGF), PD-1/LAG-3, TIGIT/TGF-Beta bispecific antibodies. In June 2022, cadonilimab was approved by the NMPA and became the first commercialized PD-1 based bispecific drug globally. Another Akeso internally discovered and developed oncology product, penpulimab (a PD-1 antibody), was granted marketing approval in China in August 2021. In December 2022, the Company out-licensed breakthrough bispecific antibody, ivonescimab (PD-1/VEGF bi-specific antibody, AK112), with up to US$5 Billion total potential deal value to Summit Therapeutics for development and commercialization in the U.S., Canada, Europe, and Japan.
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SOURCE Akeso, Inc. | https://www.wsaz.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ | 2023-07-31T05:39:51 | 0 | https://www.wsaz.com/prnewswire/2023/07/31/akeso-inc-published-2023-interim-results-positive-profit-alert/ |
BANGKOK (AP) — Shares were mostly higher in Asia on Monday after Wall Street got back to climbing following more encouraging profit reports and the latest signal that inflation is loosening its chokehold on the economy.
Sentiment also has been boosted by revived hopes for more stimulus from Beijing for the sluggish Chinese economy. Chinese factory activity contracted in July as export orders shrank, a survey showed, adding to pressure on the ruling Communist Party to reverse an economic slowdown.
A purchasing managers’ index issued by the national statistics agency and an industry group improved to 49.3 from June’s 49 on a 100-point scale but was below the 50-point level that shows activity contracting.
“The PMI surveys suggest that China’s economic recovery continued to lose momentum in July,” Julian Evans-Pritchard of Capital Economics said in a commentary. “Looking forward, policy support is needed to prevent China’s economy from slipping into a recession, not least because external headwinds look set to persist for a while longer.”
The Hang Seng in Hong Kong rose 1.5% to 20,208.78 while the Shanghai Composite index advanced 0.6% to 3,296.58.
Tokyo’s Nikkei 225 index was up 1.1% at 33,133.39. In Seoul, the Kospi climbed 0.7% to 2,626.86.
Australia’s S&P/ASX 200 edged 0.1% lower, to 7,399.00 and the SET in Bangkok was up 0.6%. The Sensex in India was little changed.
On Friday, the S&P 500 rose 1% to 4,582.23, closing out its ninth winning week in the last 11. The Dow added 0.5% to 35,459.29 and the Nasdaq climbed 1.9% to 14,316.66 as Big Tech stocks led the market.
Stocks have been rising recently on hopes high inflation is cooling enough to get the Federal Reserve to stop hiking interest rates. That in turn could allow the economy to continue growing and avoid a long-predicted recession.
A report on Friday bolstered those hopes, saying the inflation measure the Fed prefers to use slowed last month by a touch more than expected. Perhaps just as importantly, data also showed that total compensation for workers rose less than expected during the spring. While that’s discouraging for workers looking for bigger raises, investors see it adding less upward pressure on inflation.
The hope among traders is that the slowdown in inflation means Wednesday’s hike to interest rates on by the Federal Reserve will be the final one of this cycle. The federal funds rate has leaped to a level between 5.25% and 5.50%, up from virtually zero early last year. High interest rates work to lower inflation by slowing the entire economy and hurting prices for stocks and other investments.
Though critics say the stock market’s rally may have gone too far, too fast, hopes for a halt to rate hikes helped technology stocks and others seen as big beneficiaries from easier rates to rally and lead the market Friday.
Microsoft, Apple and Amazon each rose at least 1.4% and were the three strongest forces pushing upward on the S&P 500.
Companies also continued to deliver stronger profits for the spring than analysts expected. Roughly halfway through the earnings season, more companies than usual are topping profit forecasts, according to FactSet.
Intel rose 6.6% after reporting a profit for the latest quarter, when analysts were expecting a loss.
Food giant Mondelez International climbed 3.7% after reporting stronger results for the spring than expected. The company behind Oreo and Ritz also raised its forecasts for financial results for the full year.
In other trading on Monday, U.S. benchmark crude oil gave up 42 cents to $80.16 a barrel in electronic trading on the New York Mercantile Exchange. It gained 49 cents to $80.58 on Friday.
Brent crude, the international standard, shed 47 cents to $83.94 a barrel.
The U.S. dollar rose to 141.87 Japanese yen from Friday’s 141.01 yen. The euro slipped to $1.1012 from $1.1019. ___
AP Business Writer Joe McDonald in Beijing contributed. | https://www.seattletimes.com/business/stock-market-today-asia-shares-gain-after-wall-st-rally-as-investors-pin-hopes-on-china-stimulus/?utm_source=RSS&utm_medium=Referral&utm_campaign=RSS_all | 2023-07-31T05:39:52 | 0 | https://www.seattletimes.com/business/stock-market-today-asia-shares-gain-after-wall-st-rally-as-investors-pin-hopes-on-china-stimulus/?utm_source=RSS&utm_medium=Referral&utm_campaign=RSS_all |