Trade Name stringlengths 3 57 ⌀ | Generic/Proper Name(s) stringlengths 4 79 | Active Ingredient(s) stringlengths 4 64 ⌀ | Cardiotoxicity stringclasses 3
values | DICT Concern stringclasses 6
values | Keywords stringlengths 5 112 ⌀ | DIC Severity Level stringclasses 5
values |
|---|---|---|---|---|---|---|
Ravicti | GLYCEROL PHENYLBUTYRATE | GLYCEROL PHENYLBUTYRATE | null | no | QTcI) for RAVICTI was below 10 ms | null |
OPSUMIT | MACITENTAN | macitentan | Heart Damage | less | hypotension | mild |
ONGLYZA | SAXAGLIPTIN | saxagliptin hydrochloride | Heart Damage | most | heart failure | severe |
DIFICID; Dificid | FIDAXOMICIN | FIDAXOMICIN | null | no | null | null |
Wakix | PITOLISANT HYDROCHLORIDE | PITOLISANT HYDROCHLORIDE | Arrhythmia | most | QT Interval Prolongation | moderate |
Xadago | SAFINAMIDE MESYLATE | SAFINAMIDE MESYLATE | Heart Damage | less | hypertension | mild |
Turalio | PEXIDARTINIB | PEXIDARTINIB HYDROCHLORIDE | Heart Damage | less | Hypertension | mild |
CAPRELSA | VANDETANIB | VANDETANIB | Mixed | most | prolong the QT interval/Heart failure | severe |
Zydelig | IDELALISIB | IDELALISIB | null | no | not prolong the QT/QTc interval | null |
Benznidazole | BENZNIDAZOLE | BENZNIDAZOLE | null | no | null | null |
Dipentum | OLSALAZINE SODIUM | OLSALAZINE SODIUM | Mixed | less | myocarditis | severe |
PEMAZYRE | PEMIGATINIB | PEMIGATINIB | null | ambiguous | patients with electrocardiogram QT prolonged | null |
Isturisa | OSILODROSTAT | OSILODROSTAT PHOSPHATE | Arrhythmia | most | QT interval prolongation | moderate |
Prograf | TACROLIMUS | anhydrous tacrolimus | Heart Damage | less | Myocardial Hypertrophy | mild |
ONGENTYS | OPICAPONE | OPICAPONE | Heart Damage | less | hypotension | mild |
Priftin | RIFAPENTINE | RIFAPENTINE | Mixed | less | tachycardia/pericarditis | mild |
Matulane | PROCARBAZINE HYDROCHLORIDE | PROCARBAZINE HYDROCHLORIDE | Mixed | less | Hypotension/tachycardia | mild |
Katerzia | AMLODIPINE | Amlodipine Benzoate | Heart Damage | most | acute myocardial infarction | severe |
FACTIVE | GEMIFLOXACIN MESYLATE | GEMIFLOXACIN MESYLATE | Arrhythmia | most | prolong the QT interval | severe |
Juxtapid | LOMITAPIDE MESYLATE | LOMITAPIDE MESYLATE | Mixed | less | Angina pectoris/Palpitations | moderate |
Dibenzyline | PHENOXYBENZAMINE HYDROCHLORIDE | PHENOXYBENZAMINE HYDROCHLORIDE | null | ambiguous | tachycardia(Drug Interactions) | null |
NUBEQA | DAROLUTAMIDE | DAROLUTAMIDE | Mixed | less | cardiac failure/arrest | severe |
Lynparza | OLAPARIB | OLAPARIB | null | no | null | null |
Sovaldi | SOFOSBUVIR | SOFOSBUVIR | null | ambiguous | requiring pacemaker
intervention(Coadministered with Amiodarone) | null |
Edarbi | AZILSARTAN KAMEDOXOMIL | Azilsartan kamedoxomil | null | ambiguous | Hypotens ionin Volume- or Salt-Depleted Patients | null |
PYtest | UREA, C-14 | Urea C-14 | null | no | not prolong the QT/QTc interval | null |
Pranactin-Citric | UREA C-13 | UREA C-13 | null | no | null | null |
Odomzo | SONIDEGIB | SONIDEGIB PHOSPHATE | null | no | not prolong the QT/QTc interval | null |
TEPMETKO | TEPOTINIB HYDROCHLORIDE | Tepotinib Hydrochloride | null | no | not prolong the QT/QTc interval | null |
Keveyis | DICHLORPHENAMIDE | DICHLORPHENAMIDE | Heart Damage | less | cardiac failure | severe |
Fanapt | ILOPERIDONE | ILOPERIDONE | Mixed | most | QTc prolongation/hypotension | moderate |
Agrylin | ANAGRELIDE HYDROCHLORIDE | ANAGRELIDE HYDROCHLORIDE ANHYDROUS | Mixed | most | increases the QTc interval /Hypertension | mild |
Livmarli | MARALIXIBAT CHLORIDE | maralixibat chloride | null | no | null | null |
Lucemyra | LOFEXIDINE HYDROCHLORIDE | LOFEXIDINE HYDROCHLORIDE | Mixed | most | prolongs the QT interval/hypotension | severe |
SYMPROIC | NALDEMEDINE | naldemedine tosylate | null | no | not prolong the QT/QTc interval | null |
Otezla | APREMILAST | APREMILAST | null | no | null | null |
Invirase | SAQUINAVIR MESYLATE | SAQUINAVIR MESYLATE | Mixed | most | Torsade de pointes | severe |
Inrebic | FEDRATINIB HYDROCHLORIDE | FEDRATINIB HYDROCHLORIDE | Heart Damage | most | myocardial infarction | severe |
Idhifa | ENASIDENIB MESYLATE | ENASIDENIB MESYLATE | Heart Damage | most | pericardial effusion | severe |
VIIBRYD | VILAZODONE HYDROCHLORIDE | VILAZODONE HYDROCHLORIDE | Arrhythmia | less | Palpitations | mild |
Hepsera | ADEFOVIR DIPIVOXIL | adefovir dipivoxil | null | no | null | null |
ANZEMET | DOLASETRON MESYLATE | DOLASETRON MESYLATE | Arrhythmia | most | prolongs the QT interval | severe |
TABRECTA | CAPMATINIB | CAPMATINIB | null | no | not prolong the QT/QTc interval | null |
JANUVIA | SITAGLIPTIN | SITAGLIPTIN PHOSPHATE | Heart Damage | most | heart failure | severe |
Corlanor | IVABRADINE | IVABRADINE HYDROCHLORIDE | Arrhythmia | most | heart block | moderate |
Radiogardase | PRUSSIAN BLUE INSOLUBLE CAPSULES | FERRIC FERROCYANIDE | null | no | null | null |
Trintellix | VORTIOXETINE | VORTIOXETINE HYDROBROMIDE | null | ambiguous | QTc was below 10 ms | null |
TAVALISSE | FOSTAMATINIB | FOSTAMATINIB | Heart Damage | most | increases the QTc interval /Hypertension | mild |
Alinia | NITAZOXANIDE | NITAZOXANIDE | null | no | null | null |
Vyvanse | LISDEXAMFETAMINE DIMESYLATE | LISDEXAMFETAMINE DIMESYLATE | Mixed | most | Sudden death/myocardial infarction/Heart rate | severe |
Hetlioz; Hetlioz LQ | TASIMELTEON | TASIMELTEON | null | no | null | null |
Pradaxa | DABIGATRAN ETEXILATE MESYLATE | DABIGATRAN ETEXILATE MESYLATE | Heart Damage | most | myocardial infarction | severe |
TPOXX | TECOVIRIMAT MONOHYDRATE | TECOVIRIMAT MONOHYDRATE | null | no | not prolong the QT/QTc interval | null |
IRESSA | GEFITINIB | GEFITINIB | null | no | null | null |
Mycapssa | OCTREOTIDE | Octreotide | Arrhythmia | most | QT prolongation | moderate |
Orenitram | TREPROSTINIL | treprostinil | null | ambiguous | not been evaluated in a
thorough QTc study. | null |
Ruzurgi | AMIFAMPRIDINE | Amifampridine | null | no | not prolong the QTc interval | null |
Adempas | RIOCIGUAT | RIOCIGUAT | Heart Damage | less | Hypotension | mild |
MAYZENT | SIPONIMOD | SIPONIMOD | Mixed | less | atrioventricular conduction delays /Hypertension | mild |
Savella | MILNACIPRAN HYDROCHLORIDE | MILNACIPRAN HYDROCHLORIDE; milnacipran hydrochloride | Mixed | less | Elevated Heart Rate/Elevated Blood Pressure | mild |
Sapropterin Dihydrochloride | SAPROPTERIN DIHYDROCHLORIDE | SAPROPTERIN DIHYDROCHLORIDE | Heart Damage | less | myocardial infarction | severe |
BELVIQ XR; Belviq | LORCASERIN HYDROCHLORIDE HEMIHYDRATE | LORCASERIN HYDROCHLORIDE HEMIHYDRATE | Mixed | most | Regurgitant cardiac valvular disease/Heart Rate Decreases | severe |
SPRYCEL | DASATINIB | dasatinib | Mixed | most | cardiac ischemic events/QT Prolongation | severe |
SOLOSEC | SECNIDAZOLE | SECNIDAZOLE | null | no | no clinically relevant increase in the QTc | null |
DURLAZA | ACETYLSALICYLIC ACID | Aspirin | null | no | reduce the risk of death and myocardial infarction | null |
Diacomit | STIRIPENTOL | Stiripentol | null | no | null | null |
PROCYSBI | CYSTEAMINE BITARTRATE | Cysteamine bitartrate | null | ambiguous | Benign Intracranial Hypertension | null |
Auryxia | FERRIC CITRATE | TETRAFERRIC TRICITRATE DECAHYDRATE | null | no | null | null |
Synthroid | LEVOTHYROXINE SODIUM | LEVOTHYROXINE | Mixed | less | myocardial infarction/ cardiac arrest | severe |
TIBSOVO | IVOSIDENIB | ivosidenib | Arrhythmia | most | QT (QTc) prolongation | severe |
MYTESI | CROFELEMER | CROFELEMER | null | no | not prolong the QTc interval | null |
Livtencity | MARIBAVIR | MARIBAVIR | null | no | not prolong the QTc interval | null |
ALECENSA | ALECTINIB HYDROCHLORIDE | ALECTINIB HYDROCHLORIDE | Arrhythmia | less | bradycardia | mild |
Xcopri; Xcopri Maintenance Pack; Xcopri Titration Pack | CENOBAMATE | CENOBAMATE | Arrhythmia | most | QT Shortening | moderate |
Cevimeline | CEVIMELINE | CEVIMELINE HYDROCHLORIDE | Mixed | less | tachycardia, bradycardia/ hypotension, hypertension | mild |
Orgovyx | RELUGOLIX | RELUGOLIX | Arrhythmia | most | prolong the QT/QTc interval | severe |
Rayaldee | CALCIFEDIOL | CALCIFEDIOL | Heart Damage | less | congestive heart failure | severe |
Tetracycline Hydrochloride | TETRACYCLINE HYDROCHLORIDE | TETRACYCLINE HYDROCHLORIDE | null | ambiguous | Intracranial hypertension | null |
AUSTEDO; Austedo | DEUTETRABENAZINE | DEUTETRABENAZINE | Arrhythmia | most | prolong the QT interval | severe |
SIRTURO | BEDAQUILINE FUMARATE | Bedaquiline Fumarate | Arrhythmia | most | QT Prolongation | moderate |
Lorbrena | LORLATINIB | LORLATINIB | Mixed | most | 3 degree atrioventricular (AV) block/Hypertension | severe |
QELBREE | VILOXAZINE HYDROCHLORIDE | VILOXAZINE HYDROCHLORIDE | Mixed | less | Increase in Heart Rate or Blood Pressure | mild |
Trecator | ETHIONAMIDE | ETHIONAMIDE | null | no | null | null |
TAVNEOS | AVACOPAN | AVACOPAN | Heart Damage | less | Hypertension | null |
XELJANZ; XELJANZ XR | TOFACITINIB | TOFACITINIB CITRATE | Heart Damage | most | myocardial infarction | severe |
Moxidectin | MOXIDECTIN | MOXIDECTIN | Heart Damage | less | symptomatic orthostatic hypotension | mild |
Desvenlafaxine | DESVENLAFAXINE | DESVENLAFAXINE | Heart Damage | less | increases in blood pressure | mild |
NUPLAZID | PIMAVANSERIN TARTRATE | pimavanserin tartrate | Arrhythmia | most | QT Interval Prolongation | moderate |
Venclexta | VENETOCLAX | Venetoclax | null | no | no large effect on QTc interval | null |
SLYND | DROSPIRENONE | DROSPIRENONE | null | no | null | null |
Linzess | LINACLOTIDE | LINACLOTIDE | null | ambiguous | hypotension and electrolyte abnormalities (hypokalemia and hyponatremia) | mild |
Myrbetriq | MIRABEGRON | MIRABEGRON | Heart Damage | less | increase blood pressure | mild |
STEGLATRO | ERTUGLIFLOZIN | ERTUGLIFLOZIN PIDOLATE | null | no | not prolong QTc | null |
RAZADYNE | GALANTAMINE HYDROBROMIDE | galantamine hydrobromide | Arrhythmia | most | heart block | moderate |
Daypro | OXAPROZIN | OXAPROZIN | Heart Damage | most | myocardial infarction | severe |
Stivarga | REGORAFENIB | REGORAFENIB MONOHYDRATE | Heart Damage | most | myocardial ischemia and infarction | severe |
ACCRUFER | FERRIC MALTOL | FERRIC MALTOL | null | no | null | null |
LAMPIT | NIFURTIMOX | NIFURTIMOX | null | ambiguous | Hypersensitivity reaction:hypotension | null |
PEXEVA | PAROXETINE MESYLATE | PAROXETINE MESYLATE | Mixed | less | tachycardia/angina pectoris | mild |
GEMTESA | VIBEGRON | vibegron | null | no | not prolong QTc | null |
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