Trade Name stringlengths 3 57 ⌀ | Generic/Proper Name(s) stringlengths 4 79 | Active Ingredient(s) stringlengths 4 64 ⌀ | Cardiotoxicity stringclasses 3
values | DICT Concern stringclasses 6
values | Keywords stringlengths 5 112 ⌀ | DIC Severity Level stringclasses 5
values |
|---|---|---|---|---|---|---|
ZYPITAMAG | PITAVASTATIN MAGNESIUM | PITAVASTATIN | null | no | null | null |
BREXAFEMME | IBREXAFUNGERP | IBREXAFUNGERP CITRATE | null | no | not prolong QTc | null |
HIPREX | METHENAMINE HIPPURATE | METHENAMINE HIPPURATE | null | no | null | null |
Tybost | COBICISTAT | COBICISTAT | null | no | null | null |
VERQUVO | VERICIGUAT | VERICIGUAT | Heart Damage | less | Hypotension | mild |
Rozlytrek | ENTRECTINIB | ENTRECTINIB | Mixed | most | congestive heart failure /QT Interval Prolongation | severe |
XIFAXAN | RIFAXIMIN | RIFAXIMIN | null | no | null | null |
PIZENSY | LACTITOL | LACTITOL | Heart Damage | less | Increased blood pressure | mild |
Avandia | ROSIGLITAZONE MALEATE | ROSIGLITAZONE MALEATE | Heart Damage | most | congestive heart failure | severe |
EMFLAZA | DEFLAZACORT | DEFLAZACORT | Heart Damage | less | elevation of blood pressure | mild |
Ketek | TELITHROMYCIN | telithromycin | Arrhythmia | most | torsades de pointes | severe |
Daurismo | GLASDEGIB | GLASDEGIB | Arrhythmia | most | QTc prolongation | moderate |
ORFADIN | NITISINONE | NITISINONE | null | no | null | null |
ZYKADIA | CERITINIB | CERITINIB | Arrhythmia | most | QTc interval prolongation | moderate |
Vumerity | DIROXIMEL FUMARATE | diroximel fumarate | null | no | not prolong the QTc interval | null |
Multaq | DRONEDARONE | Dronedarone | Mixed | most | Class IV heart failure/atrial fibrillatio n | severe |
Cenestin | SYNTHETIC CONJUGATED ESTROGENS, A | ESTROGENS, CONJUGATED SYNTHETIC A | Heart Damage | most | myocardial infarction and strok | severe |
Quazepam | QUAZEPAM | QUAZEPAM | null | no | null | null |
Northera | DROXIDOPA | DROXIDOPA | Heart Damage | most | supine hypertension | mild |
Boniva | IBANDRONATE SODIUM | IBANDRONATE SODIUM | Heart Damage | less | Hypertension | mild |
Livalo | PITAVASTATIN CALCIUM | pitavastatin calcium | null | no | not prolongation of the QTc interval | null |
Olumiant | BARICITINIB | baricitinib | Heart Damage | most | sudden cardiovascular death | severe |
Zokinvy | LONAFARNIB | LONAFARNIB | Heart Damage | less | Hypertension | mild |
ZONTIVITY | VORAPAXAR | VORAPAXAR SULFATE | null | no | no effect on the QTc interval | null |
RYDAPT | RYDAPT | MIDOSTAURIN | Mixed | less | Cardiac failure/QT prolongation | severe |
CALQUENCE | ACALABRUTINIB | ACALABRUTINIB | Arrhythmia | less | atrial fibrillation/atrial flutter | mild |
citalopram | CITALOPRAM | CITALOPRAM HYDROBROMIDE | Arrhythmia | most | QT-Prolongation and Torsade de Pointes | severe |
Alunbrig | BRIGATINIB | brigatinib | Mixed | less | Bradycardia/Hypertension | mild |
FARYDAK | PANOBINOSTAT | PANOBINOSTAT LACTATE | Mixed | most | cardiac ischemic events/severe arrhythmias | severe |
ZEJULA | NIRAPARIB | niraparib | Heart Damage | less | Hypertension | mild |
Jardiance | EMPAGLIFLOZIN | empagliflozin | null | no | null | null |
Fycompa | PERAMPANEL | PERAMPANEL | null | ambiguous | Multiorgan hypersensitivity:myocarditis | null |
BRILINTA | TICAGRELOR | TICAGRELOR | Arrhythmia | most | ventricular pauses | moderate |
DOPTELET | AVATROMBOPAG MALEATE | AVATROMBOPAG MALEATE | null | no | not prolong the QTc interval | null |
Ibrance | PALBOCICLIB | PALBOCICLIB | null | no | no effect on QTc | null |
Gilenya | FINGOLIMOD HCL | FINGOLIMOD HYDROCHLORIDE | Mixed | most | third-degree AV block/Increased Blood Pressure | severe |
TYKERB | LAPATINIB | LAPATINIB DITOSYLATE | Mixed | most | decrease LVEF/QT Prolongation | moderate |
Cholbam | CHOLIC ACID | CHOLIC ACID | null | no | null | null |
amiloride hydrocloride | AMILORIDE HYDROCLORIDE | AMILORIDE HYDROCHLORIDE | Mixed | less | Angina pectoris/Arrhythmia | mild |
VEMLIDY | TENOFOVIR ALAFENAMIDE | TENOFOVIR ALAFENAMIDE FUMARATE | null | no | not affect the QT/QTc interval | null |
UKONIQ | UMBRALISIB | umbralisib tosylate | null | no | null | null |
TABLOID | THIOGUANINE | THIOGUANINE | null | no | null | null |
azithromycin | AZITHROMYCIN | azithromycin | Mixed | less | Arrhythmias/chest pain | mild |
Vraylar | CARIPRAZINE | CARIPRAZINE | Heart Damage | less | hypotension | mild |
Tasigna | NILOTINIB | NILOTINIB | Arrhythmia | most | prolongs the QT interval | moderate |
Revlimid | LENALIDOMIDE | LENALIDOMIDE | Heart Damage | most | myocardial infarction | severe |
Toviaz | FESOTERODINE FUMARATE | FESOTERODINE FUMARATE | Mixed | less | angina/QT prolongation on ECG | severe |
Lenvima | LENVATINIB | LENVATINIB | Mixed | most | cardiomyopathy/QT Interval Prolongation | severe |
PURINETHOL | MERCAPTOPURINE | MERCAPTOPURINE | null | no | null | null |
Aplenzin | BUPROPION HYDROBROMIDE | BUPROPION HYDROBROMIDE | Heart Damage | less | hypertension | mild |
Chemet | SUCCIMER | SUCCIMER | Arrhythmia | less | Arrhythmia | mild |
Aemcolo | RIFAMYCIN | Rifamycin | null | no | null | null |
COMETRIQ | CABOZANTINIB | cabozantinib s-malate | Heart Damage | less | Hypertension | mild |
Stendra | AVANAFIL | AVANAFIL | Heart Damage | less | angina | moderate |
Cerdelga | ELIGLUSTAT | eliglustat | Arrhythmia | most | increases in ECG intervals (PR, QTc, and QRS) | moderate |
Krintafel | TAFENOQUINE SUCCINATE | TAFENOQUINE SUCCINATE | null | no | not prolong the QTc interval | null |
Kerendia | FINERENONE | FINERENONE | null | no | not prolong the QTc interval | null |
ESBRIET | PIRFENIDONE | PIRFENIDONE | null | no | no evidence that ESBRIET
prolonged the QTc interval | null |
LOKELMA | SODIUM ZIRCONIUM CYCLOSILICATE | SODIUM ZIRCONIUM CYCLOSILICATE | null | no | null | null |
Pomalyst | POMALIDOMIDE | POMALIDOMIDE | Heart Damage | most | myocardial infarction | severe |
Galafold | MIGALASTAT HYDROCHLORIDE | MIGALASTAT HYDROCHLORIDE | null | no | not prolong the QT interval | null |
DYANAVEL XR; Dyanavel XR | AMPHETAMINE | AMPHETAMINE | Mixed | most | myocardial infarction/Heart Rate Increases | severe |
Tasmar | TOLCAPONE | Tolcapone | Mixed | less | heart failure/tachycardia | severe |
RETEVMO | SELPERCATINIB | selpercatinib | Mixed | most | QT Interval Prolongation/Hypertension | moderate |
XTAMPZA ER | OXYCODONE | OXYCODONE | Heart Damage | less | hypotension | mild |
INLYTA | AXITINIB | AXITINIB | Heart Damage | most | cardiac failure | severe |
Thiola EC | TIOPRONIN | TIOPRONIN | Heart Damage | less | congestive heart failure | severe |
SCEMBLIX | ASCIMINIB | ASCIMINIB HYDROCHLORIDE | Mixed | most | cardiac failure/QTc prolongation, | severe |
Mekinist | TRAMETINIB | TRAMETINIB DIMETHYL SULFOXIDE | Heart Damage | most | cardiac failure | severe |
FIBRICOR | FENOFIBRIC ACID | Fenofibric Acid | null | no | null | null |
KISQALI | RIBOCICLIB | RIBOCICLIB SUCCINATE | Arrhythmia | most | prolong the QT interval | severe |
GOCOVRI | AMANTADINE | AMANTADINE | Heart Damage | less | hypotension | mild |
Aptiom | ESLICARBAZEPINE ACETATE | ESLICARBAZEPINE ACETATE | null | ambiguous | Multiorgan hypersensitivity:myocarditis | null |
Tafinlar | DABRAFENIB | DABRAFENIB MESYLATE | Heart Damage | most | cardiomyopathy | severe |
Osphena | OSPEMIFENE | OSPEMIFENE | Heart Damage | most | myocardial infarction | severe |
Enablex | DARIFENACIN | DARIFENACIN | Arrhythmia | less | palpitations | mild |
Trimethoprim | TRIMETHOPRIM | TRIMETHOPRIM | null | no | null | null |
BRUKINSA | ZANUBRUTINIB | ZANUBRUTINIB | Arrhythmia | less | Atrial fibrillation | mild |
UBRELVY | UBROGEPANT | UBROGEPANT | null | no | not prolong the QT interval | null |
TRUSELTIQ | INFIGRATINIB | INFIGRATINIB | null | no | not prolong the QT interval | null |
Nexavar | SORAFENIB | SORAFENIB | Mixed | most | cardiac ischemia/infarction/QT Prolongation | severe |
QINLOCK | RIPRETINIB | Ripretinib | Heart Damage | most | cardiac failure | severe |
Primsol | TRIMETHOPRIM HYDROCHLORIDE | TRIMETHOPRIM HYDROCHLORIDE | null | no | null | null |
Nerlynx | NERATINIB | NERATINIB MALEATE | null | no | not prolong the QT interval | null |
XARELTO; Xarelto | RIVAROXABAN | rivaroxaban | null | no | null | null |
Afinitor; Afinitor Disperz | EVEROLIMUS | EVEROLIMUS | Mixed | less | congestive cardiac failure /Tachycardia | severe |
Viramune | NEVIRAPINE | NEVIRAPINE | null | no | null | null |
VIRACEPT | NELFINAVIR MESYLATE | NELFINAVIR MESYLATE | Arrhythmia | less | torsades de pointes | moderate |
Iclusig | PONATINIB HYDROCHLORIDE | ponatinib hydrochloride | Mixed | most | fatal myocardial infarction/cardiac arrhythmias | severe |
Xenical | ORLISTAT | ORLISTAT | null | no | null | null |
HYCAMTIN | TOPOTECAN | TOPOTECAN HYDROCHLORIDE | null | no | null | null |
Xtandi | ENZALUTAMIDE | ENZALUTAMIDE | Heart Damage | most | ischemic heart disease | severe |
SUNOSI | SOLRIAMFETOL | SOLRIAMFETOL | Mixed | less | Blood Pressure Heart Rate Increases | mild |
ELMIRON | PENTOSAN POLYSULFATE SODIUM | PENTOSAN POLYSULFATE SODIUM | null | no | null | null |
PIFELTRO | DORAVIRINE | doravirine | null | no | not prolong the QT interval | null |
Plaquenil | HYDROXYCHLOROQUINE SULFATE | HYDROXYCHLOROQUINE SULFATE | Mixed | most | Cardiomyopathy/QT prolongation | severe |
BRAFTOVI | ENCORAFENIB | ENCORAFENIB | Arrhythmia | most | QTc interval prolongation | moderate |
ENJUVIA | SYNTHETIC CONJUGATED ESTROGENS, B | ESTROGENS, CONJUGATED SYNTHETIC B | Heart Damage | most | myocardial infarction | severe |
Firdapse | AMIFAMPRIDINE PHOSPHATE | amifampridine phosphate | Heart Damage | less | Hypertension | mild |
Xermelo | TELOTRISTAT ETHYL | telotristat ethyl | null | no | not prolong the QT interval | null |
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