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Introduction Durability is a key requirement for the broad acceptance of bariatric surgery . We report on durability at and beyond 10 years with a systematic review and meta- analysis of all reports providing data at 10 or more years and a single-centre study of laparoscopic adjustable gastric b and ing ( LAGB )... | [
"Importance Sleeve gastrectomy is increasingly used in the treatment of morbid obesity , but its long-term outcome vs the st and ard Roux-en-Y gastric bypass procedure is unknown . Objective To determine whether there are differences between sleeve gastrectomy and Roux-en-Y gastric bypass in terms of weight ... | 4118a0ae-06ff-11f0-808a-c43d1ab1c353 |
This review examines the effect of a dual task on the gait parameters of older adults with a mean gait speed of 1.0 m/s or greater , and the effect of type and complexity of task . A systematic review of Web of Science , PubMed , SCOPUS , Embase , and PsycINFO was performed in July 2016 . Twenty-three studies ( ... | [
"Background Recent findings suggest that executive function ( EF ) plays a critical role in the regulation of gait in older adults , especially under complex and challenging conditions , and that EF deficits may , therefore , contribute to fall risk . The objective of this study was to evaluate if reduced EF is... | 4118a0f4-06ff-11f0-808a-c43d1ab1c353 |
OBJECTIVES To identify the content and reporting details of r and omised controlled trials of yoga for musculoskeletal conditions through a systematic review of the literature . DESIGN Twenty electronic data bases were search ed to identify r and omised controlled trials ( RCTs ) of yoga interventions for ... | [
"Background The CONSORT statement is intended to improve reporting of r and omised controlled trials and focuses on minimising the risk of bias ( internal validity ) . The applicability of a trial ’s results ( generalisability or external validity ) is also important , particularly for pragmatic trials .... | 4118a130-06ff-11f0-808a-c43d1ab1c353 |
Purpose The aim of this study was to systematic ally review the literature on antibiotic prophylaxis in gynaecologic surgeries to prevent inflammatory complications after gynaecological operations . The study was carried out as a systematic review . Methods Only r and omised controlled trials of women undergoing... | [
"A prospect i ve , r and omized , multicenter study was conducted on the efficacy and safety of two prophylactic antibiotic regimens in both abdominal and vaginal hysterectomy . Patients received three intravenous doses of clindamycin ( 900 mg ) plus either aztreonam ( 1 g ) or cefotaxime ( 1 g ) ; the ... | 4118a16c-06ff-11f0-808a-c43d1ab1c353 |
BACKGROUND Antipsychotics are commonly prescribed for women suffering psychotic illnesses during pregnancy and the postpartum period . The potential adverse consequences of these different options are multiple and complex , impacting on the foetus , neonate , infant and early development of the child as well as the... | [
"This article reports the psychometric properties of two scales for rating positive and negative schizophrenic signs and symptoms . These Positive and Negative Syndrome Scales consist of items selected from the Children 's Psychiatric Rating Scale ( CPRS ) , which contains items covering a wide range of chi... | 4118a1a8-06ff-11f0-808a-c43d1ab1c353 |
AIMS Diabetes mellitus ( DM ) and atrial fibrillation ( AF ) share pathophysiological links , as supported by the high prevalence of AF within DM patients . Catheter ablation of AF ( AFCA ) is an established therapeutic option for rhythm control in drug resistant symptomatic patients . Its efficacy and safety ... | [
"Background — Data regarding the long-term efficacy of atrial fibrillation ( AF ) ablation are still lacking . Methods and Results —Two hundred four consecutive patients symptomatic for paroxysmal or persistent/permanent AF were r and omly assigned to 2 different ablation schemes : pulmonary vein isolation ( P... | 4118a1e4-06ff-11f0-808a-c43d1ab1c353 |
OBJECTIVE To assess the effect of antihypertensive treatment on mortality and cardiovascular morbidity in people with diabetes mellitus , at different blood pressure levels . DESIGN Systematic review and meta-analyses of r and omised controlled trials . DATA SOURCES CENTRAL , Medline , Embase , and BIOSIS were se... | [
"OBJECTIVE Blood pressure control can reduce the risk of coronary heart disease ( CHD ) among diabetic patients ; however , it is not known whether the lowest risk of CHD is among diabetic patients with the lowest blood pressure level . RESEARCH DESIGN AND METHODS We performed a prospect i ve cohort study... | 4118a220-06ff-11f0-808a-c43d1ab1c353 |
Background The aim of this study was to review the effects of developmental care in neonatal intensive care unit ( NICU ) setting on mental and motor development of preterm infants . Method We search ed PubMed , EMBASE , CINAHL , Scopus , Web of Science and Cochrane library until October 8th 2017 , and included r... | [
"OBJECTIVE : To examine whether cycled lighting ( CL ) conditions during neonatal care in very preterm infants ( decrease crying and fussing behavior , improve the consolidation of sleep , and influence activity behavior at 5 and 11 weeks ’ postterm corrected age ( CA ) compared with preterm infants cared... | 4118a25c-06ff-11f0-808a-c43d1ab1c353 |
BACKGROUND AND OBJECTIVE : Fatigue is common in chronic health conditions in childhood , associated with decreased quality of life and functioning , yet there are limited data to compare assessment instruments across conditions and childhood development . Our objective was to describe fatigue assessment instruments ... | [
"PURPOSE / OBJECTIVES To evaluate self-reports of fatigue by young cancer survivors ( aged 11 - 18 years ) , to compare young survivors ' fatigue scores with the scores of a healthy control group and of the parent proxy evaluation , and to analyze whether demographic or disease-related factors are associa... | 4118a298-06ff-11f0-808a-c43d1ab1c353 |
AIM To evaluate the effect of silymarin on the serum levels of alanine aminotransferase ( ALT ) , aspartate aminotransferase ( AST ) and gamma glutamyl transpeptidase ( γGT ) in patients with liver diseases . METHODS A systematic review with meta- analysis of ramdomized and controlled clinical trials was performe... | [
"Background Nonalcoholic fatty liver disease ( NAFLD ) is one of the most common reasons of enzyme increase in liver . In About 10 percent of patients with NAFLD , the disease progresses toward Non Alcoholic Steatohepatitis ( NASH ) and about one third of them may progress toward cirrhosis , liver dysfunction , and... | 4118a2d4-06ff-11f0-808a-c43d1ab1c353 |
Cancer patients often experience multiple distressing symptoms which are challenging to manage . It would therefore be helpful to find a treatment that alleviates more than one symptom , to avoid polypharmacy : mirtazapine has been used in several studies for this purpose . The objective of this study was to assess... | [
"Cancer patients are commonly associated with various physical and psychological symptoms . In palliative setting , the aims are to relieve those symptoms , improve quality of life , and increase medication adherence among cancer patients . Antidepressants are generally accepted for the treatment of depress... | 4118a310-06ff-11f0-808a-c43d1ab1c353 |
BACKGROUND Psychotic disorders can lead some people to become agitated . Characterised by restlessness , excitability and irritability , this can result in verbal and physically aggressive behaviour - and both can be prolonged . Aggression within the psychiatric setting imposes a significant challenge to clinicia... | [
"Positive psychotic symptoms , such as threat/\"control-override \" delusions or comm and hallucinations , have been related to aggression in patients with schizophrenia . However , retrospective data collection has hampered evaluation of the direct influence of psychopathology on aggressive behavior . In this st... | 4118a34c-06ff-11f0-808a-c43d1ab1c353 |
BACKGROUND Statins have proven efficacy in the reduction of cardiovascular events , but the financial impact of its widespread use can be substantial . OBJECTIVE To conduct a cost-effectiveness analysis of three statin dosing schemes in the Brazilian Unified National Health System ( SUS ) perspective . METHODS We... | [
"BACKGROUND Increased levels of the inflammatory biomarker high-sensitivity C-reactive protein predict cardiovascular events . Since statins lower levels of high-sensitivity C-reactive protein as well as cholesterol , we hypothesized that people with elevated high-sensitivity C-reactive protein levels but withou... | 4118a388-06ff-11f0-808a-c43d1ab1c353 |
The primary objective of this study was to analyze the most up-to- date evidence regarding whether and how blood sugar regulation influences cardiovascular health promotion and disease prevention by carrying out an umbrella review . Three separate , systematic literature search es identified 2,343 papers in total .... | [
"Background —Arterial distensibility measures , generally from pulse-wave velocity ( PWV ) , are widely used with little knowledge of relationships to patient outcome . We tested whether aortic PWV predicts cardiovascular and all-cause mortality in type 2 diabetes and glucose-tolerance – tested ( GTT ) multiet... | 4118a3c4-06ff-11f0-808a-c43d1ab1c353 |
Musculoskeletal disorders in aging and pain are closely connected because of multiple mechanisms leading to loss of mobility and autonomy . Pain is predictive of diability and worsening frailty and the strength of this relationship increases with the severity of pain . This study presents a systematic review of r and o... | [
"This study was design ed to evaluate the effects of enriching an essential amino acid ( EAA ) mixture with leucine on muscle protein metabolism in elderly and young individuals . Four ( 2 elderly and 2 young ) groups were studied before and after ingestion of 6.7 g of EAAs . EAAs were based on the compositio... | 4118a400-06ff-11f0-808a-c43d1ab1c353 |
OBJECTIVE : A retrospective review of appendectomies performed at the University of Kansas Medical Center between January 1 , 1989 , and January 1 , 1994 , was conducted . In addition , the literature evaluating effectiveness of incidental appendectomy in preventing future operation and morbidity from appendiciti... | [
"Reports in the surgical literature are conflicting as to whether appendectomy \" in passing \" during laparotomy for trauma or for some other disease state does or does not significantly increase patient morbidity or mortality . A chart survey of all appendectomies ( 342 for acute appendicitis and 146 as in... | 4118a43c-06ff-11f0-808a-c43d1ab1c353 |
This study aim ed to perform a systematic review of studies that address the influence of physical activity on the quality of life and functional independence of adult individuals with spinal cord injury . The review was performed using data obtained from the MEDLINE , CINAHL , SciELO , LILACS , SPORTD iscus , ... | [
"Study design : Follow-up study of seven individuals with spinal cord injury ( SCI ) who completed a 9-month r and omized control trial ( RCT ) of exercise training . Objective : In a 9-month RCT conducted in our lab , individuals with SCI who participated in a twice-weekly supervised exercise training repo... | 4118a478-06ff-11f0-808a-c43d1ab1c353 |
BACKGROUND The role of oral ascorbic acid ( vitamin C ) in the prevention and treatment of colds remains controversial despite many controlled trials . There have also been a number of efforts to synthesize and /or overview the results of these trials , and controversy over what these overviews tell us . OBJECTIVES... | [
" We analysed self-reported cold data for 95 pairs of identical twins who took part in a double-blind trial of vitamin C tablets . One member of each twin pair took vitamin C and the other took a well matched placebo each day for 100 days . Vitamin C had no significant effect except for shortening the ... | 4118a4b4-06ff-11f0-808a-c43d1ab1c353 |
BACKGROUND Agitated or violent behaviour constitutes 10 % of all emergency psychiatric treatment . Some guidelines do not recommend the use of chlorpromazine for rapid tranquillisation but it is still often used for this purpose . OBJECTIVES To examine the effects of oral or intramuscular chlorpromazine for psychos... | [
"To comprehend the results of a r and omised controlled trial ( RCT ) , readers must underst and its design , conduct , analysis , and interpretation . That goal can be achieved only through total transparency from authors . Despite several decades of educational efforts , the reporting of RCTs needs improvement ... | 4118a4f0-06ff-11f0-808a-c43d1ab1c353 |
BACKGROUND Several studies suggest differences between fibrates and statins in lowering plasma fibrinogen ( Fib ) concentrations , but the evidence is not definitive . Therefore , the aim of this meta- analysis of head-to-head r and omized trials was to compare the efficacy of statins and fibrates on plasm... | [
"OBJECTIVE This study evaluated the effect of a atorvastatin-fenofibrate combination on lipid profile , in comparison to each drug alone , in patients with type 2 diabetes and combined hyperlipidemia ( CHL ) . RESEARCH DESIGN AND METHODS A total of 120 consecutive patients , who were free of coronary artery ... | 4118a52c-06ff-11f0-808a-c43d1ab1c353 |
BACKGROUND Work-related upper limb and neck musculoskeletal disorders ( MSDs ) are one of the most common occupational disorders worldwide . Studies have shown that the percentage of office workers that suffer from MSDs ranges from 20 to 60 per cent . The direct and indirect costs of work-related upper limb MSDs have... | [
"Background Both low back pain ( LBP ) and neck pain ( NP ) are major occupational health problems . In the workplace , participatory ergonomics ( PE ) is frequently used on musculoskeletal disorders . However , evidence on the effectiveness of PE to prevent LBP and NP obtained from r and omised controlled ... | 4118a568-06ff-11f0-808a-c43d1ab1c353 |
Patients with ulcerative colitis , a type of inflammatory bowel disease , report negative impacts of disease symptoms on work-related outcomes , including absenteeism and presenteeism . As a way to better underst and the impact of this disease and its treatment on work-related outcomes , the current review examin... | [
"The efficacy and safety of 4-g 5-aminosalicylic acid enemas were assessed in 153 patients with ulcerative colitis involving up to 50 cm of distal colon . Seventy-six patients received active medication and 77 received a placebo . There were 20 dropouts ( 6 in the active group and 14 in the placebo group ... | 4118a5a4-06ff-11f0-808a-c43d1ab1c353 |
Health risk behaviours ( HRB ) across the lifespan have been associated with higher cumulative physiological burden as measured by allostatic load ( AL ) . This study examines the contribution of HRB and their effects on multisystem biological risk associated with morbidity and early mortality . We systematic ally ... | [
"OBJECTIVE Only a few prospect i ve studies have examined the relationship between the frequency of cigarette smoking and the incidence of diabetes mellitus . The purpose of this study was to determine whether greater frequency of cigarette smoking accelerated the development of diabetes mellitus , and whethe... | 4118a5ea-06ff-11f0-808a-c43d1ab1c353 |
Insufficient amounts of physical activity is a risk factor for ( recurrent ) stroke . People with a stroke or transient ischemic attack ( TIA ) have a high risk of recurrent stroke and have lower levels of physical activity than their healthy peers . Though several review s have looked at the effects of lifestyle in... | [
"Objective : Despite evidence demonstrating that risk-factor management is effective in reducing recurrent cerebrovascular disease , there are very few structured care programmes for stroke survivors . The aim was to implement and evaluate an integrated care programme in stroke . Methods : 186 patients with st... | 4118a626-06ff-11f0-808a-c43d1ab1c353 |
Over the past decade , minimally invasive surgery has gained popularity as a means of optimising early postoperative rehabilitation and increasing patient satisfaction and cosmesis following total hip arthroplasty ( THA ) . However , this surgical exposure has also been associated with increased risk of iatrogen... | [
"Background For total hip arthroplasty ( THA ) , minimally invasive surgery ( MIS ) uses a smaller incision and less muscle dissection than the classic approach ( CLASS ) , and may lead to faster rehabilitation . Questions / purpose sDoes minimally invasive hip arthroplasty result in superior clinical out... | 4118a662-06ff-11f0-808a-c43d1ab1c353 |
Purpose Long-acting growth hormone ( GH ) has been developed to address the noncompliance and decreased efficacy associated with daily GH injections . We aim ed to evaluate the efficacy and safety of long-acting GH replacement therapy in children with short stature . Methods R and omized controlled trials ( RCT... | [
"Context Daily injections are required for growth hormone ( GH ) replacement therapy , which may cause low compliance as a result of inconvenience and distress in patients . Objective C-terminal peptide-modified human GH ( MOD-4023 ) is developed for once-a-week dosing regimen in GH-deficient ( GHD ) adults and ... | 4118a69e-06ff-11f0-808a-c43d1ab1c353 |
BACKGROUND Pain management is integral to the management of hip fracture . PURPOSE To review the benefits and harms of pharmacologic and nonpharmacologic interventions for managing pain after hip fracture . DATA SOURCES 25 electronic data bases ( January 1990 to December 2010 ) , gray literature , trial... | [
" A series of 80 patients with cervical , trochanteric or subtrochanteric hip fractures were r and omized to either treatment without traction , skin traction , or skeletal traction during the 1883 h between admission and operation . The institution of skin or skeletal traction was not particularly painfu... | 4118a6da-06ff-11f0-808a-c43d1ab1c353 |
Background : Nonalcoholic fatty liver disease ( NAFLD ) has become prevalent in recent decades , especially in developed countries , and approaches for the prevention and treatment of NAFLD are not clear . The aim of this research was to analyze and summarize r and omized controlled trials that investigated the effec... | [
"BACKGROUND According to previous studies , probiotic and prebiotic supplementation have desirable effects on glycemic parameters . Thus far , the effect of supplementation on the glycemic parameters and adipokines in non-alcoholic fatty liver disease ( NAFLD ) has not been assessed . Therefore , the aim of t... | 4118a716-06ff-11f0-808a-c43d1ab1c353 |
BACKGROUND Sedentary behaviour and its association with dietary intake in young people and adults are important topics and were systematic ally review ed in 2011 . There is a need to up date this evidence given the changing nature of sedentary behaviour and continued interest in this field . This review aims to a... | [
"BACKGROUND Sedentary activities , such as watching television , may disrupt habituation to food cues , thereby increasing motivation to eat and energy intake . OBJECTIVE These experiments were design ed to examine the effect of television watching on habituation of ingestive behavior in children . DE... | 4118a752-06ff-11f0-808a-c43d1ab1c353 |
OBJECTIVE To provide a broader evidence summary to inform dietary guidelines of the effect of tree nuts on criteria of the metabolic syndrome ( MetS ) . DESIGN We conducted a systematic review and meta- analysis of the effect of tree nuts on criteria of the MetS. DATA SOURCES We search ed MEDLINE , EMBASE , CINAHL ... | [
"Almonds , together with other nuts , reduce serum cholesterol levels and may reduce the risk of coronary heart disease . There is much current interest in the relation of coronary heart disease to postpr and ial events . We have therefore assessed the effects of varying amounts of almonds on the postpr ... | 4118a78e-06ff-11f0-808a-c43d1ab1c353 |
BACKGROUND Gait speed is a quick , inexpensive , reliable measure of functional capacity with well-documented predictive value for major health-related outcomes . Numerous epidemiological studies have documented gait speed in healthy , community-dwelling older people . The purpose of this study is to undertake ... | [
"OBJECTIVES To identify the most responsive method of measuring gait speed , to estimate the responsiveness of other outcome measures , and to determine whether gait speed predicts discharge destination in acute stroke . DESIGN A prospect i ve cohort study . SETTING Five acute-care hospitals . PATIENTS Fifty s... | 4118a7ca-06ff-11f0-808a-c43d1ab1c353 |
CONTEXT : Several studies have suggested an association between functional defecation disorders ( FDDs ) and overweight/obesity in children . OBJECTIVE : To synthesize current evidence evaluating the association between FDDs and overweight/obesity in children . DATA SOURCES : PubMed , Medline , and Embase were se... | [
"The purpose of this study was to investigate the prevalence , clinical characteristics , and management of functional constipation at pediatric gastroenterology clinics . A prospect i ve survey using the Rome III criteria was distributed to a group of parents of children with a constipation history and its ... | 4118a806-06ff-11f0-808a-c43d1ab1c353 |
Background Obesity-related dyslipidaemia comprises hypercholesterolaemia , hypertriglyceridaemia , low HDL-cholesterol and normal to raised LDL-cholesterol levels . 40 % of morbidly obese surgical patients have dyslipidaemia . Roux-en-Y gastric bypass ( RYGB ) surgery has many beneficial metabolic effects , but t... | [
"Background —Recent clinical trials have demonstrated that aggressive lipid lowering by statins could prevent recurrent events after acute coronary syndrome ( ACS ) . We hypothesized that this efficacy was caused by a significant reduction in plaque volume by aggressive LDL cholesterol ( LCL-C ) lowering . Th... | 4118a842-06ff-11f0-808a-c43d1ab1c353 |
Field walking tests are commonly employed to evaluate exercise capacity , assess prognosis and evaluate treatment response in chronic respiratory diseases . In recent years , there has been a wealth of new literature pertinent to the conduct of the 6-min walk test ( 6MWT ) , and a growing evidence base desc... | [
"BACKGROUND AND OBJECTIVE Cycle ergometer training is an important component of pulmonary rehabilitation for patients with COPD . However , incremental cycle tests from which individualized cycle training intensity can be prescribed may not be readily available to clinicians . The aims of the study were to ( ... | 4118a87e-06ff-11f0-808a-c43d1ab1c353 |
CONTEXT Prostate cancer patients , especially those on and rogen deprivation therapy ( ADT ) , experience many symptoms that make it difficult to maintain their independence and quality of life . Because ADT acts by means of reducing testosterone production , exercise may offset many of the ADT side effects and tho... | [
"Goals of workProstate cancer patients receiving and rogen deprivation therapy ( ADT ) are vulnerable to a number of potentially debilitating side effects , which can significantly impact quality of life . The role of alternate therapies , such as physical activity ( PA ) , in attenuating these side effec... | 4118a8ba-06ff-11f0-808a-c43d1ab1c353 |
There is substantial interest in the therapeutic potential of cannabidiol ( CBD ) , a nonpsychoactive cannabinoid found in plants of the genus Cannabis . The goal of the current systematic review was to characterize the existing literature on this topic and to evaluate the credibility of CBD as a c and i date pharm... | [
"CONTEXT Hypothetically , topiramate can improve drinking outcomes among alcohol-dependent individuals by reducing alcohol 's reinforcing effects through facilitation of gamma-aminobutyric acid function and inhibition of glutaminergic pathways in the corticomesolimbic system . OBJECTIVE To determine if topiram... | 4118a8f6-06ff-11f0-808a-c43d1ab1c353 |
BACKGROUND Palm oil contains a high amount of saturated fat compared with most other vegetable oils , but studies have reported inconsistent effects of palm oil on blood lipids . OBJECTIVE We systematic ally review ed the effect of palm oil consumption on blood lipids compared with other cooking oils using da... | [
"We have compared the effects of three different margarines , one based on palm oil ( PALM-margarine ) , one based on partially hydrogenated soybean oil ( TRANS-margarine ) and one with a high content of polyunsaturated fatty acids ( PUFA-margarine ) , on serum lipids in 27 young women . The main purpose of the... | 4118a932-06ff-11f0-808a-c43d1ab1c353 |
Objectives : To summarise quantitatively the available evidence relating to pretraumatic , peritraumatic and posttraumatic characteristics that may increase or decrease the risk of developing posttraumatic stress disorder ( PTSD ) following spinal cord injury ( SCI ) . Study design : Systematic review . Methods : Se... | [
"OBJECTIVE To conduct a prospect i ve study of the occurrence of psychological disorders and comorbidities after spinal cord injury ( SCI ) , determine psychotropic medication usage , and establish predictors of psychological disorders after transition to the community . DESIGN Longitudinal design with multiple... | 4118a96e-06ff-11f0-808a-c43d1ab1c353 |
Background Total hip or knee arthroplasty is an elective procedure that is usually accompanied by substantial blood loss , which may lead to acute anemia . As a result , almost half of total joint arthroplasty patients receive allogeneic blood transfusions ( ABT ) . Many studies have shown that post-operative au... | [
"BACKGROUND AND OBJECTIVES Red cell transfusion is commonly used in orthopaedic surgery . Evidence suggests that a restrictive transfusion strategy may be safe for most patients . However , concern has been raised over the risks of anaemia in those with ischaemic cardiac disease . Perioperative silent myocar... | 4118a9aa-06ff-11f0-808a-c43d1ab1c353 |
PURPOSE Blue-blocking ( BB ) spectacle lenses , which attenuate short-wavelength light , are being marketed to alleviate eyestrain and discomfort when using digital devices , improve sleep quality and potentially confer protection from retinal phototoxicity . The aim of this review was to investigate the relative ben... | [
"To evaluate the effects of filtering short wavelength light on visual performance under intense light conditions among pseudophakic patients previously implanted with a clear intraocular lens ( IOL ) . This was a patient-masked , r and omized crossover study conducted at 6 clinical sites in the United Sta... | 4118a9f0-06ff-11f0-808a-c43d1ab1c353 |
BACKGROUND When used as an adjunctive with antipsychotics , certain vitamins and minerals may be effective for improving symptomatic outcomes of schizophrenia , by restoring nutritional deficits , reducing oxidative stress , or modulating neurological pathways . METHOD We conducted a systematic review of all r an... | [
"BACKGROUND Vitamin B6 , or pyridoxine , plays an intrinsic role in the synthesis of certain neurotransmitters that take part in development of psychotic states . Several reports indicate that vitamin B6 may be a factor in a number of psychiatric disorders and related conditions , such as autism , Alzheimer 's ... | 4118aa2c-06ff-11f0-808a-c43d1ab1c353 |
OBJECTIVE To present the essential guidelines for non-pharmacological management of patients with psychomotor agitation in Brazil . METHODS These guidelines were developed based on a systematic review of articles published from 1997 to 2017 , retrieved from MEDLINE ( PubMed ) , Cochrane Data base of Systematic Re... | [
"Background Patient aggression is a common problem in acute psychiatric wards and calls for preventive measures . The timely use of preventive measures presupposes a preceded risk assessment . The Norwegian Brøset-Violence-Checklist ( BVC ) is one of the few instruments suited for short-time prediction of viole... | 4118aa68-06ff-11f0-808a-c43d1ab1c353 |
Abstract Purpose We tested whether short-term vitamin D supplementation improves insulin resistance in patients with kidney disease , a condition with little intrinsic vitamin D activity . Methods PubMed , EMBASE and CENTRAL were search ed for relevant observational studies and r and omized clinical trials ( RC... | [
"The effects of intravenous 1,25 dihydroxycholecalciferol [ (OH)2D3 ] on glucose tolerance and insulin secretion were studied in eleven uremic patients on regular hemodialysis and compared with eleven healthy controls . Intravenous glucose tolerance tests ( IVGTT ) were used to assess glucose tolerance , an... | 4118aaa4-06ff-11f0-808a-c43d1ab1c353 |
OBJECTIVE This study aim ed to verify whether the saddle seat provides lower ergonomic risk than conventional seats in dentistry . METHODS This review followed the PRISMA statement and a protocol was created and registered in PROSPERO ( CRD42017074918 ) . Six electronic data bases were search ed as primary study ... | [
"Aims : To identify the work factors that predict intense low back pain ( LBP ) and LBP related sick leaves in nurses ’ aides . Methods : The sample comprised 4266 r and omly selected Norwegian nurses ’ aides , not bothered or only a little bothered by LBP during the previous three months , and not on sick lea... | 4118aae0-06ff-11f0-808a-c43d1ab1c353 |
This systematic review and meta- analysis aim ed to evaluate the survival rate of ceramic and resin inlays , onlays , and overlays and to identify the complication types associated with the main clinical outcomes . Two review ers search ed PubMed , EMBASE , and the Cochrane Central Register of Controlled Trials ... | [
"PURPOSE The present follow-up study was carried out to evaluate the performance of Class II Cerec inlays after 10 years of clinical service . MATERIAL S AND METHODS Sixty-six Class II CAD/CAM ceramic inlays were placed in 27 patients . Each patient received at least one inlay luted with a dual-cured resin com... | 4118ab1c-06ff-11f0-808a-c43d1ab1c353 |
Background Although psychological interventions are recommended for the management of coronary heart disease ( CHD ) , there remains considerable uncertainty regarding their effectiveness . Design Systematic review and meta- analysis of r and omised controlled trials ( RCTs ) of psychological interventions for CH... | [
"& NA ; The feasibility of altering a Type A style of life was investigated in 1012 nonsmoking predominantly male postinfa rct ion volunteers in the San Francisco Bay area . A total of 862 were r and omly allocated into an experimental section receiving a combination of Type A and cardiac counseling , or a con... | 4118ab58-06ff-11f0-808a-c43d1ab1c353 |
BACKGROUND AND METHODS The author conducted a systematic review of the literature to evaluate the efficacy of antigingivitis and antiplaque products in six-month trials . He search ed electronic data bases for six-month r and omized clinical studies that evaluated both antiplaque and antigingivitis properties of ... | [
"The effects of a stabilized 0.454 % stannous fluoride dentifrice , currently marketed as Crest Gum Care , on supragingival plaque , gingivitis , gingival bleeding and oral soft tissue condition were studied in 328 adult male and female subjects who completed a six-month , double blind clinical study . Follow... | 4118ab94-06ff-11f0-808a-c43d1ab1c353 |
The objective of this study was to perform a systematic review on training outcomes influencing physical fitness , activity of daily living performance , and quality -of-life in institutionalized older people . We review ed 27 studies on older people ( age , ≥70 yrs ) in long-term care facilities and nursing homes... | [
"OBJECTIVE To use two different exercise programs over a 2-year period to reduce falls and their sequelae among residents of two long-term care facilities . DESIGN R and omized , controlled trial . SETTING The study took place at two long-term care facilities with services ranging from independent living t... | 4118abda-06ff-11f0-808a-c43d1ab1c353 |
Objective Functional dyspepsia ( FD ) is a chronic gastroduodenal disorder . Individuals with FD demonstrate visceral hypersensitivity , abnormal central pain processing , and low mood , but it is unclear whether psychotropic drugs are an effective treatment for the condition . We performed a systematic review and ... | [
"BACKGROUND & AIMS The Rome III criteria for functional dyspepsia have been changed to include 2 distinct syndromes : postpr and ial distress syndrome and epigastric pain syndrome . We investigated risk factors for functional dyspepsia among the functional dyspepsia subgroups defined by the Rome III criteria . ME... | 4118ac20-06ff-11f0-808a-c43d1ab1c353 |
Abstract The introduction of new technologies for diagnosis and screening programs led to an increasing rate of early detection of colorectal cancer . This , associated with the evolution of endoscopic techniques of local excision , led to the assessment of new strategies to reduce morbidity related to treatmen... | [
"Purpose We design ed American College of Surgeons Oncology Group ( ACOSOG ) Z6041 , a prospect i ve , multicenter , single-arm , phase II trial to assess the efficacy and safety of neoadjuvant chemoradiation ( CRT ) and local excision ( LE ) for T2N0 rectal cancer . Here , we report tumor response , CRT-r... | 4118ac5c-06ff-11f0-808a-c43d1ab1c353 |
STUDY QUESTION Does fertility treatment influence cognitive ability in school aged children , and does the impact vary with the type of treatment ? SUMMARY ANSWER The available high- quality evidence indicates that specific treatments may give rise to different effects on cognitive development , with certain ... | [
"BACKGROUND As a continuation of two large-scale , multicentre studies on the development of 5-year-old ICSI children , we present results of the follow-up study undertaken on the cognitive and motor development of 8-year-old ICSI children . METHODS Developmental outcomes of 151 8-year-old singletons born thro... | 4118ac98-06ff-11f0-808a-c43d1ab1c353 |
Background : Patient-reported outcome measures ( PROMs ) are important tools for assessing outcomes following injuries to the h and and wrist . Many commonly used PROMs have no evidence of reliability , validity , and responsiveness in a h and and wrist trauma population . This systematic review examines the PROM... | [
"BACKGROUND Outcome measurement following surgery is increasingly the focus of attention in current health-care debates because of the rising costs of medical care and the large variety of operative options . The purpose of the present study was to correlate quality of life after volar locked plate fixation o... | 4118ace8-06ff-11f0-808a-c43d1ab1c353 |
Background Subacromial shoulder pain is a common clinical presentation with much diagnostic uncertainty . Some of this uncertainty relates to the involvement of the cervical spine as a source or contribution to subacromial shoulder pain . Currently , there is no accepted method of screening of the cervical spine in t... | [
"BACKGROUND While physical therapy is an effective element in the rehabilitation of rotator cuff ( RC ) disease , the most effective sequence of exercise training interventions has not been defined . HYPOTHESIS/ PURPOSE The purpose of this study is to determine if there is a difference in pain or function ... | 4118ad24-06ff-11f0-808a-c43d1ab1c353 |
OBJECTIVE The current study was performed to assess the evidence for effects of therapeutic intervention with mobile device applications ( apps ) for individuals with autism spectrum disorder ( ASD ) . DESIGN The main methodology of the current study was systematic review with meta- analysis . SETTING Only r and ... | [
"Background Web-based and mobile health interventions ( also called “ Internet interventions ” or \" eHealth/mHealth interventions \") are tools or treatments , typically behaviorally based , that are operationalized and transformed for delivery via the Internet or mobile platforms . These include electronic to... | 4118ad6a-06ff-11f0-808a-c43d1ab1c353 |
Background Selective serotonin reuptake inhibitors ( SSRIs ) are the most commonly prescribed antidepressants for the treatment of depression in patients with Parkinson 's Disease ( PD ) but data on their efficacy are controversial . Methods We conducted a systematic review and meta- analysis of r and omized contro... | [
"INTRODUCTION On average 40 % of all patients suffering from Parkinson s disease ( PD ) undergo bouts of depression . It is thought that this is due to a dysfunction in the orbitofrontal and dorsolateral circuits , together with hypometabolism in the orbital , cau date nucleus and frontal dorsolateral tract regio... | 4118ada6-06ff-11f0-808a-c43d1ab1c353 |
Aim / objective The objective of this study was to provide a meta- analysis examining the effects of football heading . Design Meta-analytical review on football heading effects on neurocognitive performance , cognition and symptom reports . Data sources Combinations of the key terms were entered into the following... | [
"Head impacts are common in contact sports , but only recently has there been a rising awareness of the effects of subconcussive impacts in adolescent athletes . A better underst and ing of how to attenuate head impacts is needed and therefore , this study investigated the relationship between neck strength , im... | 4118ade2-06ff-11f0-808a-c43d1ab1c353 |
BACKGROUND Reducing high blood cholesterol , a risk factor for cardiovascular disease ( CVD ) events in people with and without a past history of CVD is an important goal of pharmacotherapy . Statins are the first-choice agents . Previous review s of the effects of statins have highlighted their benefits in people... | [
"Background — Prior primary prevention trials of statin therapy that used cholesterol criteria for enrollment have not reported significant decreases in stroke risk . We evaluated whether statin therapy might reduce stroke rates among individuals with low levels of cholesterol but elevated levels of high-sen... | 4118ae1e-06ff-11f0-808a-c43d1ab1c353 |
Background and aims The Nordic diet ( ND ) , is supposed to be associated with a reduced cardiovascular risk ; however , clinical trials have led to inconsistent results regarding the effect of this diet on cardio-metabolic markers . Using systematic review and meta- analysis of r and omized controlled trials ( R... | [
"BACKGROUND Effects of diet on blood lipids are best known in white men , and effects of type of carbohydrate on triacylglycerol concentrations are not well defined . OBJECTIVE Our goal was to determine the effects of diet on plasma lipids , focusing on subgroups by sex , race , and baseline lipid concentra... | 4118ae5a-06ff-11f0-808a-c43d1ab1c353 |
Background Research has been conducted to assess the effectiveness of weight management , dietary and physical activity interventions in military setting s. However , a recent and comprehensive overview is lacking . The aim of this systematic review is to examine the evidence and describe key components of effectiv... | [
"Thirty-nine U.S. Air Force enlisted men participated in a r and omized controlled study that evaluated an experimental program design ed to enhance fitness . Subjects were assigned to either a treatment ( access to the program ) or control ( no access to program ) group for 6 months . To improve treatment gr... | 4118ae96-06ff-11f0-808a-c43d1ab1c353 |
Background Postoperative delirium is a common preventable complication experienced by older adults undergoing elective surgery . In this systematic review and meta- analysis , we identified prognostic factors associated with the risk of postoperative delirium among older adults undergoing elective surgery . M... | [
"Aim The aim of the present study was to investigate the occurrence of postoperative delirium ( POD ) in elderly patients undergoing transurethral resection of prostate ( TURP ) and to identify those factors associated with delirium . Methods From July 2010 to February 2015 , 358 patients , aged ≥65 years an... | 4118aedc-06ff-11f0-808a-c43d1ab1c353 |
It is often assumed that patients with pain-related disability due to low back pain ( LBP ) will have reduced physical activity levels , but recent studies have provided results that challenge this assumption . The aim of our systematic review was to examine the relationship between physical activity and disabil... | [
"Background Chronic low back pain remains a major health problem in Australia and around the world . Unfortunately the majority of treatments for this condition produce small effects because not all patients respond to each treatment . It appears that only 25–50 % of patients respond to exercise . The two mos... | 4118af18-06ff-11f0-808a-c43d1ab1c353 |
BACKGROUND Atrial fibrillation ( AF ) is a major cause of stroke . Although st and ard investigations after an event include electrocardiographic monitoring , the optimal duration to detect AF is unclear . We performed a systematic review and meta- analysis to determine whether the duration of electrocardiographic... | [
"Background and Purpose — Cardioembolism in paroxysmal atrial fibrillation ( pxAF ) is a frequent cause of ischemic stroke . Sensitive detection of pxAF after stroke is crucial for adequate secondary stroke prevention ; the optimal diagnostic modality to detect pxAF on stroke units is unknown . We compared 24-hou... | 4118af5e-06ff-11f0-808a-c43d1ab1c353 |
Many public health interventions provide benefits that extend beyond their direct recipients and impact people in close physical or social proximity who did not directly receive the intervention themselves . A classic example of this phenomenon is the herd protection provided by many vaccines . If these ' spillover eff... | [
"Propensity score based methods are used increasingly to evaluate the effectiveness of treatments when evidence from r and omised trials is not available . However , users need to be aware of their strengths and",
"Vaccination of one person may prevent the infection of another either because the vaccine p... | 4118af9a-06ff-11f0-808a-c43d1ab1c353 |
BACKGROUND & AIMS Previous studies have supported positive roles of antioxidant supplements on weight-loss . One antioxidant supplement is Alpha-lipoic acid . However , recommending ALA as an anti-obesity supplement remains controversial . Accordingly , the purpose of the present study was to perform a meta- ... | [
"OBJECTIVE To evaluate the potential body weight-lowering effects of dietary supplementation with eicosapentaenoic acid ( EPA ) and α-lipoic acid separately or combined in healthy overweight/obese women following a hypocaloric diet . METHODS This is a short-term double-blind placebo-controlled study with pa... | 4118afd6-06ff-11f0-808a-c43d1ab1c353 |
BACKGROUND Currently , there is no evidence -based definition for concussion that is being uniformly applied in clinical and research setting s. OBJECTIVE To conduct a systematic review of the highest- quality literature about concussion and to assemble evidence about the prevalence and associations of key indicators o... | [
"Background Neurocognitive testing has been endorsed as a “ cornerstone ’ of concussion management by recent Vienna and Prague meetings of the Concussion in Sport Group . Neurocognitive testing is important given the potential unreliability of athlete self-report after injury . Relying only on athletes'ormalities... | 4118b012-06ff-11f0-808a-c43d1ab1c353 |
Aim The purpose of this work is to give practical guidelines for radiotherapy of locally advanced , inflammatory and metastatic breast cancer at first presentation . Methods A comprehensive survey of the literature using the search phrases “ locally advanced breast cancer ” , “ inflammatory breast cancer ” , “ b... | [
"Background The role of postoperative radiotherapy in breast-conserving therapy is undisputed . However , optimal timing of adjuvant radiotherapy is an issue of ongoing debate . This retrospective clinical cohort study was performed to investigate the impact of a delay in surgery – radiotherapy intervals on... | 4118b04e-06ff-11f0-808a-c43d1ab1c353 |
The purpose of this quantitative systematic review was to appraise the evidence on the caries-preventive effect of glass ionomer cement ( GIC ) in relation to resin-based fissure sealants . Nine English and two Portuguese data bases were search ed ( 15 January 2008 ) . R and omized clinical trials and systema... | [
"The aim of the present study was to compare intraindividually a type III fissure-sealant , glass ionomer cement with a resin-based sealant . One hundred and forty-eight first permanent molars were sealed in forty-seven children . After three years 20.8 percent of the resin and 34.7 percent of the glass iono... | 4118b08a-06ff-11f0-808a-c43d1ab1c353 |
OBJECTIVE This systematic review aim ed to ( a ) identify and categorize techniques used to modify or manage impulsive processes associated with unhealthy eating behavior , ( b ) describe the mechanisms targeted by such techniques , and ( c ) summarize available evidence on the effectiveness of these techniques . MET... | [
"The majority of adults in the UK and US are overweight or obese due to multiple factors including excess energy intake . Training people to inhibit simple motor responses ( key presses ) to high-energy density food pictures reduces intake in laboratory studies . We examined whether online response inhibition trai... | 4118b0c6-06ff-11f0-808a-c43d1ab1c353 |
The aim of this paper was to conduct a systematic review of body fat distribution before and after partial and complete weight restoration in individuals with anorexia nervosa . Literature search es , study selection , method development and quality appraisal were performed independently by two authors , and data... | [
"Background / Objectives : Restrictive Anorexia nervosa ( ANR ) is an eating disorder ( ED ) characterized by a low bone mineral content ( BMC ) and by an alteration in body composition ( reduction and abnormal distribution of fat mass — FM and lean mass — LM ) . The aim of our study was to address whether bone ... | 4118b102-06ff-11f0-808a-c43d1ab1c353 |
BACKGROUND Zinc deficiency is a significant public health problem in low- and middle-income countries . Zinc is essential for the formation and migration of neurons along with the formation of neuronal synapses . Its deficiency could interfere with the formation of neural pathways and with neurotransmission , thus af... | [
"BACKGROUND Low birth weight infants have been noted to have low zinc concentrations in cord blood , and zinc deficiency in childhood is associated with reduced immunocompetence and increased infectious disease morbidity . This study investigates whether zinc supplementation of infants born full term and small... | 4118b13e-06ff-11f0-808a-c43d1ab1c353 |
INTRODUCTION Obesity is a top public health priority but interventions to reverse the condition have had limited success . About one-in-three obese adults are free of metabolic risk factor clustering and are considered ' healthy ' , and much attention has focused on the implication s of this state for obesity managem... | [
"Associations between modifiable exposures and disease seen in observational epidemiology are sometimes confounded and thus misleading , despite our best efforts to improve the design and analysis of studies . Mendelian r and omization-the r and om assortment of genes from parents to offspring that occurs during ga... | 4118b17a-06ff-11f0-808a-c43d1ab1c353 |
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